This issue of Clinics in Chest Medicine focuses on Pulmonary Complications of Non-Pulmonary Malignancy. Editors Guang-Shing Cheng and Jennifer Possick have assembled an expert team of authors on topics such as: Pulmonary manifestations of non-pulmonary solid malgnancies; Pulmonary manifestations of leukemia and lymphoma; Radiation pneumonitis; Toxicities from conventional chemotherapy; Toxicities from novel targeted therapies; Bacterial pneumonia; Fungal pneumonia; Viral pneumonia; IPS and other early onset non-infectious pulmonary syndromes; Pulmonary GVHD and other late-onset non-infectious pulmonary syndromes; Pulmonary function and pre-transplant risk assessment; Diagnostic Evaluation of Pulmonary Abnormalities in Hematologic Malignancy and HCT; Acute respiratory failure in patients with non-pulmonary malignancy; Critical care prognosis and outcomes in patients with non-pulmonary malignancy; and Palliative and end-of-life care.

Clinically focused and designed to provide a to-the-point overview, Interstitial Lung Disease, by Drs. Talmadge King, Harold Collard, and Luca Richeldi, bring you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides pulmonologists, intensivists, internal medicine physicians, and researchers with a dependable source of information on current treatment options and patient care. . Evidence for current treatment options for interstitial pneumonia, idiopathic pulmonary fibrosis, and smoking-related interstitial lung diseases. . Approach to diagnosis of interstitial lung diseases, such as sarcoidosis, hypersensitivity pneumonitis, and Churg-Strauss syndrome. . Genetic markers for inherited interstitial lung diseases such as dyskeratosis congenita, tuberous sclerosis/LAM, and hyper-IgE syndrome. . Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Dr. Goldsworthy has created a state-of-the-art issue that emphasizes the nurse's role in mechanical ventilation. Pertinent clinical topics include the following: basics of mechanical ventilation for nurses; current modes for mechanical ventilation; best practices for managing pain, sedation, and delirium in the mechanically ventilated patient; mobilization of and optimal oxygenation for the mechanicaly ventilated patient; managing complications; and effective weaning strategies. Authors also address mechanical ventilation in both children and neonates. The current content in this issue will leave nurses with the clinical information they need to effectively manage mechanically ventilated patients.

This issue of World Clinics: Pulmonary & Critical Care Medicine focuses on respiratory critical care, presenting an up-to-date collection of articles on the latest developments in the field, authored by internationally renowned experts. The book begins with an introduction to respiratory critical care and assisted ventilation. The following chapters discuss different disorders including acute COPD and asthma, acute respiratory distress syndrome, pulmonary thromboembolism, and chronic respiratory failure. The final sections cover critical care in poisoning cases, nutritional management in the ICU, interpretation of arterial blood gases and acid-base abnormalities, and ICU infections and antibiotics. Each article concludes with comments by the editor highlighting their own experience and summarising the chapter. The book is enhanced by images, table and figures. Key Points Evidence-based review of respiratory critical care topics providing an overview of the latest advances in the field Part of the World Clinics: Pulmonary & Critical Care Medicine series Each article concludes with comments by the editor Comprehensive text enhanced by images, tables and figures

Preterm birth interrupts the normal developmental progression of most organs, particularly when birth occurs at the lowest level of viability. An immediate task is to successfully transition to a post-natal life without a placental circulation. To do this demands careful management of the cardiorespiratory systems. To best help the fragile preterm infant at this demanding time, care-givers must remember two most pressing goals. These are first to maintain adequacy of gas exchange and delivery, while simultaneously minimizing any secondary injury to the fragile preterm lung. However, after these immediate priorities in the delivery room, the longer term effects of an immature lung development and its associated problems come to the forefront. These problems include the inflammation of perinatal infection, oxygen, and invasive mechanical ventilation. Both the immaturity itself, and secondary lung injury and its inflammation - collectively will often lead to the condition termed bronchopulmonary dysplasia (BPD). Although many of these infants may eventually be discharged to home without a need for oxygen supplementation or pulmonary medications, the long-term impact of interrupted lung development and secondary lung injury remain serious concerns. It is now well recognized that mechanical ventilation is pivotal to developing secondary lung injury and BPD. Consequently, a great deal of time and effort has been put into the development and application of non-invasive ventilator (NIV) approaches to supporting respiratory function in neonates. Since the landmark publication by Gregory and colleagues in 1967, nasal continuous positive airway pressure (nCPAP) has been the most commonly applied approach to NIV. This approach has been supported by the recent generation of randomized controlled trials. However, cumulatively these trials have shown only a small reduction in rates of BPD. Outside of the trial data, despite the wider application of nCPAP, rates of BPD remain relatively unchanged over recent years. This has led to investigations of other NIV approaches including nasal ventilation and high flow nasal cannula therapy. Not only have available modes increased, but so have the interfaces through which these modes may be applied. In the issue of Clinic in Perinatology, readers will find an up-to-date review of non-invasive approaches to supporting preterm respiratory function. This draws on the expertise of leading investigators in the field. This issue reviews the physiologic mechanisms by which the various approaches to NIV may support respiratory function; the evidence base supporting different NIV approaches; and adjunctive aspects of NIV therapy including their use during neonatal transport and the application of other supportive therapies such as inhaled NO.

Written by some of the world's leading practitioners - and pioneers - in the field, "Thoracic Endoscopy" is the first up-to-the-minute, expert reference for clinicians with a solid foundation in diagnostic bronchoscopy and chest medicine needing to extend their clinical expertise in response to two decades of rapid development.

"Thoracic Endoscopy" covers four key areas of practice:
advanced diagnostic bronchoscopy
the latest techniques for interventional bronchoscopy -- including the traditional rigid bronchoscopy techniques, ablative instruments and stents -- and a discussion of endobronchial lung reduction and gene therapy
a window to the pleura, covering the field of pleuroscopy and the advances in diagnosis and treatment
clinical problems and methodologies, and strategies for solving them using interventional techniques

"Thoracic Endoscopy" presents the only coherent guide to the full range of techniques and practice patterns, and is the essential reference for both experienced interventional pulmonologists and students beginning to practice in this rapidly-developing field.

This issue of Immunology and Allergy Clinics, guest edited by Dr. Andrew A. White, is devoted to Aspirin-Exacerbated Respiratory Disease. Articles in this issue include: An Overview of Non-Steroidal Anti-inflammatory Drug Reactions; The Clinical Presentation of Aspirin-Exacerbated Respiratory Disease; Diagnostic Evaluation in Aspirin-Exacerbated Respiratory Disease; Aspirin-Exacerbated Respiratory Disease as an Endotype of Chronic Rhinosinusitis; Pathogenesis of Aspirin Reactions in Aspirin-Exacerbated Respiratory Disease; Performing Aspirin Desensitization; Clinical Trials in Aspirin-Exacerbated Respiratory Disease Treatment; Eosinophils and Mast Cells in Aspirin-Exacerbated Respiratory Disease; Mechanisms of Benefit with Aspirin Therapy; Lipid Mediators in Aspirin-Exacerbated Respiratory Disease; and Epigenetic and Genetic Components of Aspirin-Exacerbated Respiratory Disease.

This issue of Clinics in Chest Medicine focuses on Advances in Mechanical Ventilation. Articles include: Mechanical Ventilation Design Features; Assessing Respiratory System Mechanical Function; Ventilator Induced Lung Injury; Managing Acute Lung Injury; Patient-Ventilator Interactions; Extracorporeal Gas Exchange; Preventing Ventilator Associated Infections; Ventilator Discontinuation Process; Ventilator Management of the Non-injured Lung; Non-invasive Ventilation; and more!

This comprehensive volume provides a balanced and easily readable account of the rise of modern sleep medicine, its history and developmental milestones. Authored by an international group of experts, the remarkable progress and fascinating evolution from rudimentary concepts of the ancient prehistoric and early classical periods to our contemporary knowledge are covered in detail. These examples and their relationship to modern therapies offer neurologists, psychiatrists, respiratory specialists, clinicians, researchers and those interested in sleep medicine an important perspective to the origins of current practice.

Collaboratively authored by international experts and innovators, this book serves as a comprehensive introduction to flexible bronchoscopy in children, a guide to normal and abnormal bronchoscopy findings, and as the first pediatric bronchoscopy text to describe the array of innovative technologies now being utilized in advanced diagnostic and interventional bronchoscopy programs. Flexible bronchoscopy is a core clinical service provided by academic pediatric pulmonary medicine programs and a critical skill that trainees are expected to develop. The role of flexible bronchoscopy in the care of children with disorders of the respiratory tract has evolved rapidly over the past decade due to technological advances in diagnostic and therapeutic instruments. While many of these tools were designed for adult patients, pediatric pulmonologists have adapted them to meet the unique needs of children. The book is organized into three sections: the history and fundamentals of flexible bronchoscopy; the role of flexible bronchoscopy in evaluation of pediatric respiratory tract disorders; and advanced diagnostic and interventional bronchoscopy. Throughout, images and videos enhance the text and provide invaluable perspective. This is an ideal guide for practicing pediatric pulmonologists and trainees, and will also prove useful to pediatric anesthesiologists, intensivists, otolaryngologists and respiratory therapists.

Prepare for success on respiratory therapy credentialing exams! Updated to reflect the 2009 National Board of Respiratory Care (NBRC) content outlines, Sills' The Comprehensive Respiratory Therapist's Exam Review, 5th Edition helps you review for both entry and advanced level credentialing exams. It covers every testable subject, providing content review, self-assessment questions, and study hints. The new Evolve website contains electronic testing offering realistic practice for the entry-level credentialing exam and the advanced-level credentialing Written Registry Exam (WRE) and Clinical Simulation Exam (CSE). Self-study questions at the end of each chapter include an answer key with rationales to help you analyze your strengths and weaknesses in content learned. UNIQUE! Exam Hint boxes point out point out subjects that are frequently tested, helping you study, plan your time, and improve your test-taking skills. Rationales for each question provide feedback for correct and incorrect answers so you understand why an answer is correct or incorrect and retain information better. Difficulty level codes (recall, application, analysis) for each question on Evolve help you prepare for questions in the way that is most appropriate (e.g., memorization for recall or synthesis for analysis). Special NBRC coding of topics corresponds to every topic covered in the NBRC Detailed Content Outline (DCO) so you can easily review each of the testable topics. Secure Evolve website lets you experience the actual NBRC testing environment in a computerized format. NEW! Therapist Multiple Choice Exam (TM-CE) practice test aligns with the new 2015 NBRC Written Exam. UPDATED! Revised content reflects the 2015 NBRC Detailed Content Outline and examination matrix so you know exactly what to expect on the exams - and can review each of the areas covered on the matrix. NEW! More analysis-type questions added to the end-of-chapter self-study questions reflect changes in the matrix content outlines. NEW! Greater consistency in formulas, abbreviations, and equations achieved through aligning the text and Evolve site to comprehensive Abbreviation and Equation Glossaries. EXPANDED! 22 clinical simulations feature shortened sections and align with the new 2015 NBRC Clinical Simulation Exam in both study mode and exam mode, giving you the opportunity to practice this difficult portion of the Registry Exam on Evolve. NEW! Standard Normal Range Guide features reference tables with normal values of various parameters used in respiratory care assessment. EXPANDED! New practice exams on Evolve, including one 140-question TM-CE with automatic scoring to delineate entry and advanced credentialing levels, let you assess your understanding in both study (untimed) and exam (timed) modes.