This book provides a comprehensive overview of how to use MRI for the imaging of lung disease. Special emphasis is placed on routine applications and the clinical impact of MRI in each setting. In addition, current technological developments are reviewed and information presented on dedicated applications of MRI in preclinical and translational research, clinical trials, and specialized institutions. During the past two decades, significant advances in the technology have enabled MRI to enter and mature in the clinical arena of chest imaging. Standard protocols are now readily available on MR scanners, and MRI is recommended as the first- or second-line imaging modality for a variety of lung diseases, not limited to cystic fibrosis, pulmonary hypertension, and lung cancer. The benefits and added value of MRI originate from its ability to both visualize lung structure and provide information on different aspects of lung function, such as perfusion, respiratory motion, ventilation, and gas exchange. On this basis, novel quantitative surrogates for lung function and therapy control (imaging biomarkers) are generated. The second edition of MRI of the Lung has been fully updated to take account of recent advances. It is written by an internationally balanced team of renowned authors representing all major groups in the field.

Guest editor Terence K. Trow has assembled an expert team of authors on the topic of Pulmonary Arterial Hypertension. Articles include: Epidemiology of Pulmonary Arterial Hypertension, Pathology of Pulmonary Hypertension, Genetics of Pulmonary Arterial Hypertension, Diagnosis of Pulmonary Arterial Hypertension, Pulmonary Hypertension Owing to Left Heart Disease, Pulmonary Hypertension due to Lung Disease and/or Hypoxia, Pulmonary Arterial Hypertension Associated with Congenital Heart Disease, World Health Organization Group 5 Pulmonary Hypertension, and more!

Guest edited by Sandra Anderson this issue of Immunology and Allergy Clinics covers all aspects of exercise-induced bronchospasm, including treatment through pharmacologic agents, patient assessments, and biomarkers.

This issue focuses on three disease sections: Diabetes, Hematology and Coagulation, and covers diagnostic and management issues during pregnancy of selected topics in each section. The chapters cover new concepts, evolving management and important impacts on the mother and unborn child.

This issue of Clinics in Chest Medicine is Guest Edited by Kristina Crothers, MD from the University of Washington and will focus on HIV and Respiratory Disease. Article topics include Abnormalities in Host Defense, Antiretroviral Therapy and Lung Immunology, HIV associated Pneumonia, HIV associated Tuberculosis, HIV associated lung malignancies, and HIV associated COPD.

This issue of Thoracic Surgery Clinics covers the screening for and diagnosis and staging of lung cancer. Expert authors review the most current information available about fluorescence and navigational bronchoscopy, integrated PET/CT for mediastinal nodal staging, contraindications to pulmonary resection, approach to patients with multiple lung nodules, and more. Keep up-to-the-minute with the latest developments in this important aspect of thoracic surgery practice.

This issue of Clinics in Chest Medicine is Guest Edited by Jon Puchalski, MD, from Yale and will focus on Pleural Disease. Article topics include Obtaining Pleural Fluid, Analyzing Pleural Fluid, Pleural Interventions and Genetic Therapy and Biomarkers.

This issue of Immunology and Allergy Clinics provides the latest essential updates in interstitial lung diseases and autoimmune lung diseases. This comprehensive issue covers causes, symptoms, diagnosis, and treatment.

This issue of Clinics in Chest Medicine, Guest Edited by Carrie A. Redlich, MD, MPH, Paul Blanc, MD, MSPH, Mridu Gulati, MD, and Ware Kuschner, MD, will focus on Occupational and Environmental Lung Diseases, with article topics including: asthma, hypersensitivity pneumonitis, and other immune-mediated lung disease; Work-exacerbated asthma; Occupational COPD; Indoor fuel exposure and the lung in both the developed and developing worlds; New (and newly recognized) occupational and environmental causes of selected chronic parenchymal and terminal airway diseases; Occupational rhinitis and other work-related upper respiratory tract conditions; Military service and lung disease; Ambient air pollution; Protecting the lungs from microbes, particles and other inhalational exposures; and Exhaled breath and induce sputum analysis in assessing the effects of occupational and environmental exposures.

Lung function testing has evolved over the years from a tool purely used for research and is now a commonly utilised form of clinical investigation. This new book is clear, concise and easy to read, providing both the essential scientific information as well as focusing on the practical aspects of lung function testing. The book is designed so that different chapters can be read as stand-alone sections, but cross-referencing to the other chapters completes the picture for the interested reader. The book begins with an outline of lung structure and anatomy, and then proceeds to basic functional considerations before discussing the tests themselves. Particular attention is given to spirometry and lung volume measurements. The text covers the functional assessment of exercise capacity, respiratory muscle strength and concludes with preoperative evaluation and recommendations. The text emphasises practical problems, including controversies associated with lung function testing. Boxes emphasise important topics throughout the text. Highlighted questions can be used for short tutorials or problem-based learning

Bronchoscopy and Central Airway Disorders provides the guidance you need to plan and implement the most effective bronchoscopy procedure for every patient. Through specifically-designed case scenarios with correlating review questions and videos, this practical respiratory medicine reference leads you through the decision-making process and execution of these sometimes complex procedures, as well as the optimal long-term management of your patients. Master various bronchoscopic approaches and techniques necessary to treat a variety of malignancies that may occur in the trachea or lungs. Consider the rationale and weigh the consequences of each approach. Case resolutions at the end of each chapter --with commentary and alternative approaches from 36 key experts in interventional bronchoscopy -- illustrate the decision-making process from patient evaluation through long-term management. Reinforce learning by correlating key concepts and practice through study questions related to each clinical scenario. See exactly how to proceed with high-quality videos online that capture crucial teaching moments and provide a walkthrough of sometimes complex procedures including the placement of airway stents via bronchoscopy for a variety of diseases and complications, such as airway collapse due to COPD. Systematically think through diagnostic and interventional (therapeutic) bronchoscopic procedures using Dr. Colt's unique "Four Box" approach: Initial Evaluation; Procedural Techniques and Results; Procedural Strategies; and Long-term Management Plan. Access the full text online at www.expertconsult.com, along with image and video libraries, review questions, and more! The case-based guidance you need to work through the decision-making process behind bronchoscopy and ultimately improve patient care.

This issue gives the general radiologist a solid overview of lung cancer imaging techniques. CT screening for lung cancer is discussed, and the evaluation and management of indeterminate pulmonary nodules is reviewed. Revised TNM lung cancer staging, as well as the optimal imaging protocols for lung cancer staging (CT, MR and PET) are thoroughly examined. A multidisciplinary approach to tissue sampling and updated histopathologic classification of lung cancer are discussed. Image-guided ablative therapies for lung cancer are reviewed. Finally, future trends in lung cancer diagnosis and staging and genetics are reviewed, as well as novel biomarkers for lung cancer detection.

This issue of Clinics in Chest Medicine, Guest Edited by Pascal Chanez MD PhD, will focus on Asthma, with article topics including: Compliance ; Epidemics in asthma ; Genotypes of asthma ; diagnose and phenotype asthma ; Unbiased biomarkers in asthma ; Asthma as a chronic infectious disease ; Childhood Asthma Management ; Occupational Asthma ; Corticosteroid Treatments ; Airway Smooth Muscle ; Resolution of Inflammation ; and Immunological Therapeutic Interventions in Asthma.

Top authors were selected to write clinical review articles devoted to Advances in Respiratory Care of the Newborn. Articles are devoted to: Effects of chorioamnionitis on lung function and growth; Delivery room respiratory management of the term and preterm infant; CPAP or INSURE for initial respiratory support; Which CPAP is best?; Non-invasive respiratory support; Volume limited and volume targeted ventilation; Weaning from mechanical ventilation; Predictors of bronchopulmonary dysplasia; Brain Injury in Chronically Ventilated Preterm Neonates: Collateral Damage Related to Ventilation Strategy; The Pulmonary Circulation in Respiratory Failure; Novel methods for assessment of right heart structure and function in pulmonary hypertension; Control of oxygenation; Non-invasive monitoring by photoplethysmography; Cell-based strategies to reconstitute lung function in infants with severe bronchopulmonary dysplasia; Permissive Hypercapnea; Prevention of BPD with Nitric Oxide; and Aero-digestive pulmonary disorders in the neonate.

This issue of Critical Care Nursing Clinics will include articles on the following topics: Non-invasive ventilation; Modes of mechanical ventilation; Mechanical ventilation effect on heart/lung interactions; Effect of ventilation on the lungs; VAP; Liberation/weaning & Sedation/pain control; Self/unplanned extubation; Communication; recovery and rehab post ICU; Airway protection with aging; home ventilation; monitoring of the mechanical vent patient; and Dyspnea.

This issue of Medical Clinics of North America provides the latest essential updates on COPD.? The following topics are covered: pathobiological mechanisms; genes and the disease (alpha-l-antitrypsin); the environment, phenotype, and comorbidity; the role and potential of imaging; pulmonary function and its importance; exercise in testing and therapy; patients' perception and quality of life; exacerbations, causes, prevention, and treatment; an integrated approach to the medical treatment; meducal pneumoplasty, surgical resection, or lung transplant; and smoking cessation and environmental hygiene.

The first issue of Clinics in Chest Medicine to be published with this focus, this issue reviews bronchiectasis from numerous angles to provide comprehensive coverage on this important subject.? Epidemiology, airway defense mechanisms, pathogenesis, imaging and genetic causes of bronchiectasis are discussed.? Allergic bronchopulmonary aspergillosis is addressed, as well as non-tuberculous mycobacteria as a cause of bronchiectasis.? Authors examine how to evaluate the success of therapy for bronchiectasis (what endpoints to use) and then discuss a variety of therapy options: inhaled and systemic antibiotic treatment, chest physiotherapy, pharmacologic agents for mucous clearance, antipinflammatory therapy and macrolides.? Pulmonary resection and lung transplantation for bronchiectasis are reviewed. Recent advances in Cystic Fibrosis are also discussed.

The Year Book of Pulmonary Disease brings you abstracts of the articles that reported the year's breakthrough developments in pulmonary disease carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. Topics such as Asthma and Cystic Fibrosis, Chronic Obstructive Pulmonary Disease, Lung Cancer, Community-Acquired Pneumonia, Lung Transplantation, Sleep Disorders, and Critical Care Medicine are represented highlighting the most current and relevant articles in the field.

The guest editors for this issue, Talmadge King, Harold Collard, celebrated pulmonary specialists from UCSF, and Luca Richeldi, renowned visiting professor to UCSF from University of Modena, Italy, bring together a state-of-the-art issue on the important topic of Interstitial Lung Diseases (ILD).? This comprehensive issue reviews the approach to diagnosis of ILD, radiology if ILD, pathology of ILD.? Idiopathic pulmonary fibrosis is discussed, including phenotypes and comorbidities, acute exacerbation and accelerated decline, management, and pathobiology of novel approaches to therapy.? Connective Tissue ILD, Chronic Hypersensitivity Pneumonitis, familial ILD and smoking-related ILD, and non-specific interstitial pneumonia are reviewed.? In the final article, lung transplantation is discussed.

Carcinoma of the lung is one of the most prevalent and aggressive types of cancer, and rates of lung cancer are on the rise.? This issue gives a comprehesive review of the most recent advances in Lung Cancer.? Epidemiology, etiology, and prevention of lung cancer is first discussed, followed by articles on pre-invasive evaluation and management, screening, pathology and molecular biology.? There is an article on the approach to the ground glass nodule.? Of great importance is the revised staging classification of Lung Cancer, which is discussed here in detail.? Articles on PET imaging, interventional pulmonary, and functional evaluation before Lung Resection are also included.? The issue then focuses on advances in treatment for early stage lung cancer, hgih risk patients with early stage lung cancer, advances in the treatment of Advanced Stage Lung Cancer, Small Cell Lung Cancer, and gene therapy for lung neoplasms.

In this issue of Surgical Oncology Clinics of North America, Guest Editor Mark Krasna and colleagues discuss a wide range of topics devoted to lung cancer.? Articles focus on pathology; updated staging systems; epidemiology of lung cancer - smoking, second hand smoke, and genetics; molecular markers for incidence, prognosis, and response to therapy; screening; diagnostic work-up; non-invasive staging techniques; surgical resection; the role of surgery following induction therapy for stage III NSCLC; the role of adjuvant chemotherapy in NSCLC (stages I-III); and much more.

This issue of Medical Clinics of North America provides general internists with the most essential timely information for the diagnosis and treatment of the pulmonary diseases that they see regularly. Topics covered include lung cancer, pleural diseases, interstitial lung disease, interventional pulmonology, asthma, chronic obstructive lung disease, community-acquired pneumonia, eosinophilic lung diseases, hypoventilation syndromes, pulmonary embolism and pulmonary hypertension, and sarcoidosis.

This issue of Immunology and Allergy Clinics of North America brings the clinician up to date on essential topics in occupational asthma.? Articles cover definition; classification; epidemiology; old and new causes; pathogenesis and disease mechanisms; clinical assessment including differential diagnosis; and management of work-related asthma and related conditions.? Other subject matter includes occupational rhinitis; irritant-induced asthma and reactive airways dysfunction; hypersensitivity pneumonitis and related conditions; and evaluation of impairment and disability.

This issue of Critical Care Clinics will focus on Severe Acute Respiratory DIstress Syndrome and dealing with it in the ICU. Topics will include: Challenges and Successes in ARDS Research;Mechanical ventilation with Lung Protective Strategies: What works?; Gene therapy for ALI/ARDS;High Frequency Oscillatory Ventilation in ALI/ARDS;Prone positioning therapy in ARDS;Recovery and Long-term outcome in ARDS; and Experimental models and emergeing hypotheses for ALI and ARDS

The Year Book of Pulmonary Disease brings you abstracts of the articles that reported the year's breakthrough developments in pulmonary disease carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. Topics such as Asthma and Cystic Fibrosis, Chronic Obstructive Pulmonary Disease, Lung Cancer, Community-Acquired Pneumonia, Lung Transplantation, Sleep Disorders, and Critical Care Medicine are represented highlighting the most current and relevant articles in the field.