As the prevalence of allergic diseases and asthma has increased in recent years, scientists have intensified research efforts to understand the pathogenesis of these sometimes debilitating conditions. Indeed, researchers have provided key insights-and new concepts-that have changed therapeutic strategies. Moreover, allergic inflammation has served as something of a model in furthering our understanding of regulatory mechanisms of inflammation in general. Presented in an encyclopedic format, the CRC Desk Reference for Allergy and Asthma provides the latest scientific information on allergic diseases and asthma. It combines knowledge from clinical immunology with basic immunology, pharmacology, biochemistry, and molecular biology to examine new treatment strategies for allergic diseases and asthma. Highlights of the CRC Desk Reference for Allergy and Asthma include: oEASE OF USE. This desk reference presents topics in alphabetical order so that they are easy to find. oCROSS-REFERENCING. Utilizes cross-referencing to aid in the rapid switch between basic and clinical science. oUNIFIED NOMENCLATURE. Greatly assists those readers who are new in the field. oHIGHLIGHTS VITAL INFORMATION. Vital information is highlighted in boxes, allowing rapid identification of key concepts. Written by leading authorities in the field, the CRC Desk Reference for Allergy and Asthma serves as a timely reference for anyone interested in this area of research. Not only does it present information in an easy-to-use format, but it addresses many hot topics and views that will have sustaining value for years to come.

Whatever affects one part of the respiratory system may affect all other parts. It's common for an allergy that festers to lead to sinusitis and then to asthma. But all these conditions involve your whole body. That's why you need to learn how to engage the healing attributes of your entire body to cure the full range of respiratory problems. As a longtime, highly regarded practitioner, Dr. Grossan has adopted a holistic methodology for allergy and sinus health in addition to conventional medical practices. He advocates what he calls the "Whole Body Approach" (WBA) that includes "tools needed to take charge of your own healing." For instance, to promote natural healing in the nose, Dr. Grossan recommends humming, because "the vibration of the sound stimulates your nasal cilia [tiny hairs] to move faster" which "breaks up thick mucus that may impede cilia movement" following an allergy season. Humming loudly and in a low frequency - such as ooommmm - doesn't allow harmful bacteria to build up which can produce the toxins that cause sinus disease. Dr. Grossan, also, recommends using pulse-wave nasal irrigation and drinking hot lemon/lime drinks or teas with honey for positive cilia movement and allergy relief. Dr. Grossan bases his WBA on new discoveries about how the body heals, particularly psychoneuroimmunology, the study of the interaction between psychological processes and the nervous and immune systems. Relaxation, smiling, humour, biofeedback and five-sensory visualisation are in this tool kit. Some WBA activities he suggests are common-sense practices. For instance, when dealing with a seasonal allergy, avoid getting chilled and get good sleep. While Dr. Grossan discusses sound, time-tested medical practices for everything from sinus headaches to postnasal drip, chronic obstructive pulmonary disease, pollution-induced bronchial inflammation, asthma, snoring, loss of smell or taste, surgery and paediatric issues, he raises WBA for every issue. Lacing the text with humorous examples of how unconventional healing techniques cured people, Dr. Grossan has written a comprehensive review of the latest treatments, both holistic and medical, for the full range of respiratory ailments.

Edited by cancer rehabilitation specialist Dr. Adrian Cristian, Lung Cancer Rehabilitation provides clinicians with a concise and accessible resource covering the holistic rehabilitation of lung cancer patients. Beginning with the epidemiology, genetics, and pathophysiology of lung cancer, it then covers clinical assessment and treatment options before providing comprehensive coverage of rehabilitation. Offering practical information, best practices and the latest advances and research, this book is a valuable reference for physical medicine and rehabilitation physicians and residents, as well as occupational therapists and physical therapists. Provides a clear understanding of the current medical, surgical and radiation treatments for lung cancer. Covers the whole spectrum of lung cancer rehabilitation, including the role of physical and occupational therapy, the treatment of anxiety and depression, integrative care, pain management, nutritional rehabilitation and more. Offers a timely and convenient resource written by leading experts in lung cancer and rehabilitation.

This timely volume brings together the latest basic and clinical insights on the cellular and mediator mechanisms involved in the induction and persistence of airway dysfunction of asthma by over 90 experts in the field-paving the way for developing novel and more effective antiinflammatory therapeutic agents and strategies.
Furnishing a comprehensive and up-to-date view of the expanding and interrelated components underlying asthma pathogenesis, Inflammatory Mechanisms in Asthma
describes how evidence on airway inflammation is obtained with invasive and noninvasive procedures, such as bronchoalveolar lavage and sputum analysis
reviews the complex interactions of inflammatory cells that contribute to chronic inflammation and bronchial hyperreactivity, including eosinophils, basophils, neutrophils, fibroblasts, epithelial cells, and macrophages
considers mast cells, cytokines, neural factors, leukotrienes, kinins, and other mediators that regulate the development, establishment, or resolution of asthma exacerbations
presents new information suggesting that airway changes in asthma can lead to remodeling or airway fibrosis
and more
Enhanced with over 4700 references, tables, drawings, and photographs, this compelling investigation into the pathophysiology of asthma is an indispensable resource for pulmonologists, physiologists, immunologists, allergists, epidemiologists, biochemists, molecular biologists, and graduate and medical school students in these disciplines.

Selected as a Doody's Core Title for 2022! Lippincott (R) Connect Featured Title Purchase the new print edition of this Lippincott (R) Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. Reflecting the trusted expertise of Dr. John B. West and Dr. Andrew M. Luks, West's Pulmonary Pathophysiology: The Essentials, Tenth Edition offers accessible explanations of disease processes that affect the respiratory system. This best-selling companion to West's Respiratory Physiology: The Essentials, 11th Edition, has served generations of students and practitioners who work with respiratory patients, presenting vital knowledge in a concise, straightforward manner that's easy to understand. Building on this legacy of success, the tenth edition is updated throughout with the latest clinical perspectives, new images, clinical vignettes, and enhanced USMLE-style review questions to help students excel in today's changing healthcare practice. UPDATED! Clinical Vignettes with open-ended questions demonstrate the real-world application of basic science and strengthen students' self-assessment. UPDATED! Radiographs, CT images, and color histopathologic sections clarify diagnostic and therapeutic approaches. UPDATED! USMLE-style multiple-choice questions, with answers, at the end of each chapter reveal areas requiring further study and boost students' test-taking confidence. Clinical features/notes boxes provide efficient, bulleted review for key diseases. End-of-chapter Key Concepts reviews reinforce essential chapter information at a glance. Appendices provide fast access to symbols, units, and normal values; further readings; and answers to multiple-choice and Clinical Vignette questions. Online video lectures, available via YouTube, engage students in the material and clarify challenging textbook concepts. Lippincott (R) Connect features: Full access to the digital version of the book with the ability to highlight and take notes on key passages for a more personal, efficient study experience. Carefully curated resources, such as interactive diagrams, audio and video tutorials, and self-assessment, all designed to facilitate further comprehension. Lippincott (R) Connect also allows users to create Study Collections to further personalize the study experience. With Study Collections you can: Pool content from books across your entire library into self-created Study Collections based on discipline, procedure, organ, concept or other topics. Display related text passages, video clips and self-assessment questions from each book (if available) for efficient absorption of material. Annotate and highlight key content for easy access later. Navigate seamlessly between book chapters, sections, self-assessments, notes and highlights in a single view/page.

This book aims to help the reader confused by a multiplicity of diseases responsible for similar symptoms in different patients. Consequently, the chapters are noticeably sign-oriented rather than disease-oriented, each dealing with one of the four cardinal modalities of HRCT presentation, namely the reticular, nodular, alveolar and cystic patterns. Each chapter is introduced by a list of diseases, immediately followed by a detailed description of each disease. All the chapters are thoroughly illustrated with high-quality, enlarged images which, like a counterpoint, provide the rhythm to the written text.

When dealing with the diseases within each pattern, only the pertinent manifestations are taken into account. This is a feature unique to this book, which sees the same disease being introduced more than once. This distinction is not artificial, since different phases in the progression of a process not only have different clinical features, but also dissimilar pathological findings, and therefore different radiological aspects.

Often, clinical presentation, history and HRCT are sufficient for making a diagnosis and defining disease management; in other cases, further investigation is required to obtain a more confident diagnosis or to determine the activity of the disease more precisely. Consequently, the contributions of other techniques involved in diagnostic refinement are also highlighted (bronchoalveolar lavage, bronchoscopic or thoracovideoscopic biopsy, open chest surgery).

Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure. The success of RSV immune prophylaxis and the availability of ever more powerful tools to study the immune response and pathogenesis of disease, combined with the ability to construct a wide variety of vaccines using different vaccine platforms, give us grounds to believe that an RSV vaccine is within reach. This book brings together in one source what is currently known about the virus: its clinical and epidemiologic features; the host response and pathogenesis of the disease; vaccines, vaccine platforms, and treatment; and animal and tissue culture models of RSV infection. It is designed to organize the critical information relevant to RSV vaccine development, facilitate the assimilation of data, and speed progress toward producing a safe and effective vaccine.

Written by world authorities, this reference explores the utilization and advancement of state-of-the-art imaging modalities for the analysis of pulmonary function-providing an up-to-date and global perspective of imaging applications with detailed contributions from experts in Europe, North America, Japan, and Australia.

Inflammatory Cells and Mediators in Bronchial Asthma provides reviews and summaries regarding state-of-the-art articles that examine the role of various inflammatory cells and their mediators in the pathogenesis of asthma. Topics include pharmacological and biochemical regulation of the airways; involvement of key inflammatory cells and the release and effect of their mediators in airway function; and the characteristics of receptors for leukotriene B4, C4, and D4, adenosine, platelet-activating factor, sensory and inflammatory peptides, and the effect of various anti-asthmatic drugs on airway inflammation. Physicians, allergists, immunologists, and pulmonary disease research scientists will find this book to be an invaluable reference resource.

Key Features * Sets the standard for training and competency of this emerging, yet scientifically approved non-invasive technique of ultrasound with all the essential information on how to perform ultrasound and interpret the images obtained. * Features clear and didactic images demonstrating echo findings in various situations along with videos of diaphragmatic ultrasound offering a unique "window" on mechanically ventilated patients, allowing to take important clinical decisions on ventilatory modes and assistance by pulmonologists, critical care specialists, thoracic surgeons, emergency medicine specialists as well as trainees. * Includes a chapter on pediatric ultrasound along with ultrasound of other respiratory muscles (i.e., intercostal and abdominal) which is emerging as a useful complementary tool.

Gastroesophageal Reflux and the Lung provides a comprehensive review of current knowledge concerning normal deglutition and foregut digestive processes and examines how abnormalities of swallowing or excessive/abnormal GER can lead to respiratory tract dysfunction and lung disease. In-depth Chapters deliver a concise review of the prevalence of GER in patients with lung disease and synthesize the current evidence regarding its diagnosis and management. Each chapter includes key points and a summary. In addition to outlining the current state of knowledge, each chapter provides a summary of ongoing research in the field and identifies the need for future research. Written by an international group of authors who are experts in their respective fields, Gastroesophageal Reflux and the Lung is a valuable resource for practicing clinicians, internists, pulmonologists and primary care personnel.

Over the past 20 years, diagnostic tests for pediatric pulmonologists have revolutionized care of children afflicted with respiratory disorders. These tests have been used to not only help in diagnosis, but also in the management and treatment of these children. Bronchoscopic, imaging and physiologic advances have improved clinical care of these children and have been used as outcome measures in research trials. Diagnostic Tests in Pediatric Pulmonology: Applications and Interpretation describes the various diagnostic modalities (especially the newer ones) that are available for the evaluation of pediatric respiratory disorders. It also provides an understanding of the advantages and limitations of each test so that the clinician may choose the most appropriate ones. An internationally renowned group of authors describe how best to interpret the key findings in a variety of tests as well as the possible pitfalls in incorrect interpretation. This volume focuses on the main diagnostic modalities used in the evaluation of pediatric patients with respiratory disorders and presents up-to-date information on the advantages and limitations of each test for a variety of conditions encountered in the practice of pediatric pulmonology. Clinical utility of these tests is also highlighted. This valuable resource is well suited to practicing clinicians, including pediatric pulmonologists, pediatricians and primary care practitioners, as well as trainees, respiratory therapists and clinical researchers.

Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies.

Histopathology of Bronchial Asthma; P.K. Jeffery. Airway Neuropeptides; P. Barnes. Potential Role of Mast Cell Proteases in Asthma; J. Nadel. Human Mast Cells, Basophils, and their Mediators; V. Casolaro, et al. Platelets and Asthma; J. Morley, et al. Leukotrienes and Asthma; J. Rokach, et al. Plasma Exudation in Asthma and its Pharmacological Control; C. Persson. Synthesis and Regulation of IgE in Asthma; G. Del Prete. Osmotic and Ionic Factors in Bronchial Responsiveness; S. Bianco, et al. Airway Responsiveness, Late-Phase Response, and Inflammation in Allergic Asthma; V. Brusasco, et al. Injury and Repair of the Airway Epithelium in Asthma; S. Rennard, et al. Bronchial Asthma and Pulmonary Gas Exchange; R.R. Rodriguez. Asthma Management; A. Tattersfield. The National Asthma Education Program; S. Hurd. Management of Asthmatic Children; K.F. Kerrebijn. 12 additional articles. Index.

This comprehensive resource brings together the most current theories, evidence and best practice parameters for the use of nocturnal non-invasive ventilation (nNIV). Chapters focus on the application of acute and chronic nNIV in patients with cardio-respiratory disorders over a range of major medical settings. Updates on past and recent research in this field are highlighted. Authored by leading clinicians and investigators, Nocturnal Non-Invasive Ventilation provides practical and cutting-edge knowledge to physicians, researchers and allied health professionals on the front lines of treating cardio-respiratory and sleep disorders.

Complete Guide to Respiratory Care in Athletes introduces the respiratory system and its function during exercise. It considers the main respiratory conditions affecting athletes and delivers practical advice for the management of respiratory issues in athletic populations. With contributions from leading international experts, the book discusses fundamental scientific principles and provides pragmatic 'hands-on' clinical guidance to enable practical application. Each chapter includes useful pedagogical features such as case studies and guides for carrying out assessments. The book covers wide a range of topics, including: respiratory system function during exercise impact of the environment on the upper and lower airways asthma related issues in athletes allergic rhinitis in athletes exercise induced laryngeal obstruction exercise induced dysfunctional breathing paterns respiratory muscle training role of screening for respiratory issues in athletes assessing and dealing with respiratory infections in athletes. This text is key reading for both newly qualified and established medical, scientific and therapy practitioners who are working with athletes with respiratory issues. It is also a valuable resource for students of sports medicine, sports therapy, and sport and exercise science courses.

Compiled by an internationally recognized team of contributors, this reference spans methods to effectively identify, diagnose, and treat this frequently challenging group of rhinopathies. Addressing both generic and disease-specific issues, this source spans possible causes of nonallergic rhinitis such as fumes, odors, temperature, atmospheric changes, smoke, and other nasal irritants, while highlighting critical scientific and clinical issues.

Respiratory Care Clinical Competency Lab Manual provides the practical skills needed to apply classroom theory to clinical practice. This text has the flexibility to be used in conjunction with all other respiratory care titles, as well as in other disciplines that require competencies in respiratory therapy. With detailed, step-by-step procedures, supporting procedural illustrations, hands-on lab exercises, case studies, and critical thinking questions, this text helps you understand and apply theoretical knowledge by demonstrating specific skills. Procedural competency evaluation forms help you to assess your progress and performance of specific procedures. Detailed, structured lab activities provide hands-on opportunities to assess psychomotor and patient communication skills in a controlled environment. Content correlation to NBRC combined CRT/RRT exam content outlines helps you better prepare for credentialing exams. Step-by-step procedural competencies prepare you for the RT competency areas established by the American Association of Respiratory Care (AARC) and meet the national practice standards for patient care. Up-to-date coverage of current technology, equipment, Clinical Practice Guidelines (CPGs), CPR guidelines, and CDC recommendations, and mass casualty/disaster management equips you with the most state-of-the-art training for respiratory care. Integration of case-based questions within the lab activities helps you develop and promote your critical thinking abilities. UNIQUE! Coverage of polysomnography addresses clinical evaluation in this expanding specialty area. Over 200 images provide visual guidance on how to perform procedures. UNIQUE! Reality Check boxes arm you with practical knowledge on real-world application of various procedures. UNIQUE! Tip boxes supply you with helpful pointers for the clinical arena. Glossary of terms offers quick reference to terms presented in the text.