Sleep Apnea: Implications in Cardiovascular and Cerebrovascular Disease specifically addresses the cardiovascular and cerebrovascular consequences of sleep apnea and is geared toward a broad readership of physicians that will ultimately aid patients suffering from sleep apnea.

The Second Edition ensures that there is a critical synthesis of existing literature and new information, linking sleep apnea to the major disease burdens faced by developed and developing nations. This synthesis includes both new basic and epidemiological data and published clinical trials linking sleep apnea to:

• inflammation
• the metabolic syndrome
• stroke
• hypertension and heart failure

Written by internationally recognized experts, Pulmonary Hypertension bridges the gap between pulmonology and cardiology to provide clinicians in both disciplines with knowledge of the signs, symptoms, diagnosis, and pharmacologic and surgical treatments for pulmonary hypertension (PH). Through the use of clinical trials, this ground-breaking text supplies a comprehensive review of both the primary and secondary clinical and investigative aspects of this condition.

Discussing controversies and concepts in PH diagnosis and management, this guide explores:

• classification and epidemiology, pathology, pathogenesis, genetics, and diagnosis of PH
• causes of the condition, such as idiopathic pulmonary arterial hypertension (IPAH)
• PAH-complicating connective tissue diseases (CTD), congenital heart diseases, human immunodeficiency virus (HIV), and other disorders
• the mechanisms, toxicities, and efficacy of therapeutic agents
• the role of combination therapies, novel agents, and future directions
• PH in specific patient populations such as pregnant and critically-ill patients in the ICU

This volume is dedicated to multidisciplinary research at the interface between basic biomedicine and clinical practice. This book guides best practice in the diagnosis and therapy while dealing with difficult-to-treat disorders of yet unclear etiology. Chapters address such disorders as granulomatosis with polyangiitis causing autoimmune-related multiorgan inflammation of blood vessels, increasingly widespread allergy to peanuts, occupational exposure to zinc oxide, and immunogenic responses to pneumococcal and influenza vaccination underlying their preventive effectiveness. Other hot issues deal with the proper use of fluid therapy in the perioperative period and a cognitive decline in lung transplant patients. A new physiotherapeutic approach of treating key myofascial trigger points in low-back pain appears highly beneficial in reducing patients' disability, advancing physiotherapy of this overwhelming condition. Finally, other chapters consider ways to streamline medical management to increase the number of physicians and their availability for patients, a particularly sensitive issue in the current COVID-19 pandemic. The dissemination of clinical knowledge about high-risk and hardly controllable conditions is an inalienable part of progress in medical practice. The book is a resource for clinical specialists, general practitioners, and allied healthcare professionals.

Concise yet comprehensive, this textbook of clinical pulmonology provides pulmonologists and respiratory disease physicians with all the key information that they need to know to manage the patient through the diagnosis and treatment journeys. From the most common condition to the rarest, each disease is consistently presented and comprehensively covered giving the reader just the key facts. Building upon the basic sciences and integrating these with clinical practice, each chapter has a consistent approach, is highly designed and visually appealing. Numerous illustrations, colour photographs, scans, bullet points, tables and algorithms ensure that the key information is available at a glance. The keynote sections serve as a useful revision aid as do the multiple choice questions. A truly international and highly experienced editorship with expert contributors from around the world ensure that the book remains a trusted source of information. Set at the level between the definitive reference work and the clinical manual, Essentials of Clinical Pulmonology is an invaluable cornerstone for all pulmonologists whether trainees or experienced clinicians.

The health-related effects of asbestos have long been mired in controversy, with industry and plaintiff attorneys playing a significant role. This comprehensive book provides a balanced and extensive evidence-based critical analysis of the literature concerning asbestos-related diseases, from a scientific and historical perspective. The book presents a carefully referenced review of the medical literature on the health effects of asbestos, and reflects the extensive experience of the author in evaluating patients with asbestos-related disorders.

Using a unique, case-based approach, Pleural Diseases: Clinical Cases and Real-World Discussions brings you up to date with the latest advances in this fast-moving subspecialty. A wide variety of real-world challenges are presented along with multiple perspectives from expert pulmonologists who discuss and analyze each case collaboratively, replicating actual patient experiences and outcomes. This first-of-its-kind resource is ideal for practicing pulmonologists and fellows, interventional pulmonologists, critical care physicians, and others who are interested in an interactive approach to everyday clinical problems related to pleural disease. Provides a unique, interactive approach to understanding the nuances and complexities of patient cases for both invasive and non-invasive therapies, drawing from real clinical cases and accompanying case discussions. Describes the approach taken by experts for each case, presenting the clinical reasoning on the most appropriate approaches and the possible therapies. Offers easy-to-read, templated information for every case: onset of symptoms, the entire diagnostic-therapeutic path including clinical and laboratory findings, and discussions on the clinical choices made in accordance with evidence-based medical procedures. Includes both positive and negative outcomes for a broader experience. Features more than 200 illustrations including x-rays, procedural photos, ultrasound, CT scans, and histopathology specimens, as well as video procedures for thoracentesis, chest tube placing, medical thoracoscopy, and insertion of indwelling pleural catheter. Addresses other common clinical issues such as the management of multimorbid elderly patients, the optimization of fluid balance, and the need to discontinue antiplatelet or anticoagulant therapy before invasive procedures. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Key Features Comprehensive coverage of all aspects of work-related asthma, including historical aspects, epidemiology and risk factors, mechanisms and genetics, other types of work-related asthma conditions and variants, hypersensitivity pneumonitis, occupational urticaria and dermatitis Assessment of the worker and workplace along with management of the worker, prevention and medicolegal aspects Of interest not only to pulmonologists, but also for industrial hygienists, researchers, lawyers and other health professionals in the field of work-related conditions Detailed information about specific agents, including a variety of high- and low-molecular weight agents

Prepare for a career as a leading respiratory therapist with the solid foundation in anatomy and physiology found in Des Jardins' best-selling CARDIOPULMONARY ANATOMY & PHYSIOLOGY: ESSENTIALS OF RESPIRATORY CARE, 7E. This extremely reader-friendly presentation delivers the most complete, accurate information about the structure and function of the respiratory system. Clear and concise coverage presents even complicated concepts in an understandable format using full-color design and proven learning features that guide you in applying what you've learned to your professional career. Thirteen new Clinical Connections add to the book's total 141 Clinical Connections that link chapter content to today's clinical setting and highlight actual situations that respiratory therapists encounter every day. These features also direct meaningful discussion and strengthen your critical-thinking skills.

Arthur McIvor and Ronald Johnston explore the experience of coal miners' lung diseases and the attempts at voluntary and legal control of dusty conditions in British mining from the late nineteenth century to the present. In this way, the book addresses the important issues of occupational health and safety within the mining industry; issues that have been severely neglected in studies of health and safety in general. The authors examine the prevalent diseases, notably pneumoconiosis, emphysema and bronchitis, and evaluate the roles of key players such as the doctors, management and employers, the state and the trade unions. Throughout the book, the integration of oral testimony helps to elucidate the attitudes of workers and victims of disease, their 'machismo' work culture and socialisation to very high levels of risk on the job, as well as how and why ideas and health mentalities changed over time. This research, taken together with extensive archive material, provides a unique perspective on the nature of work, industrial relations, the meaning of masculinity in the workplace and the wider social impact of industrial disease, disability and death. The effects of contracting dust disease are shown to result invariably in seriously prescribed lifestyles and encroaching isolation. The book will appeal to those working on the history of medicine, industrial relations, social history and business history as well as labour history.

Responding to the substantial growth that has taken place in the field over the past decade, this reference provides an in-depth overview of current thought on the genetics and genomics of asthma and COPD in relation to their pathogenesis and treatment. With contributions by an esteemed team of international authorities on the topic, this source spans the latest developments in the utilization of microarray techniques, linkage and association studies, mapping strategies, comparative genetics, microarray techniques, proteomics, and pharmacogenomics.

This timely Second Edition of a landmark reference furnishes in-depth examinations of the latest developments in the physiology, pathophysiology, and clinical relevance of the respiratory muscles and chest wall-reflecting the explosion of information that has occurred since the publication of the previous edition.

Respiratory infections constitute a major public health concern. The goal of this book is to share knowledge on the best advances in influenza and influenza-like viral infections, and new molecular-based diagnostic methods that discern the antigenic shift enabling viruses to constantly evolve and elude the host immune response. Co-infections, co-morbidities, persistently meager anti-flu vaccination coverage, and infection complications are dealt with. The chapters also further insight into such topics as the effects of sex hormones, and socioeconomic and anthropometric measures on respiratory and immune functions underlying the severity of asthma and respiratory allergy. Psychological functioning in respiratory disorders, taking into account quality of life, illness acceptance, and depressive symptoms is also reviewed as it is all too often underestimated by healthcare providers. The book is intended for clinicians, researchers, students, and all other actors in health-related issues.

Specifically focusing on the immediate management and diagnosis of patients in the intensive care unit, this reference contains expert reviews and practical care recommendations for patients with acute respiratory failure. Packed with detailed descriptions of treatment procedures and quality figures throughout each chapter, Practical Pulmonary and Critical Care Medicine will stand as a must-have armamentarium of protocols and guidelines for efficient and effective patient care.

Interstitial lung diseases comprise a significant part of any respiratory medicine practice. This timely second edition of Diffuse Lung Disease is a practical clinically-oriented resource, covering all the major advances in diagnostic techniques and therapies. Authored by world authorities in the field, this book provides clear and specific recommendations for the management of all forms of interstitial lung diseases. This book is divided into two sections. The first section addresses the general aspects of diagnosis and management, including clinical approach, radiographic approach, physiological changes, and classification. The second section details each individual form of interstitial lung disease. Organized in an easy to follow format, each disease specific chapter includes tables outlining diagnostic approach, differential diagnosis, disease monitoring, and treatment. Illustrative cases, replete with high quality HRCT images, bring an added dimension to this outstanding book.

Filling a gap in the literature, this reference provides concise and practical guidelines for the diagnosis and management of sinusitis and furnishes an authoritative outline of our current understanding of the pathophysiology of this condition. Addressing a wide spectrum of issues related to the identification, epidemiology, and etiology of sinusitis, this guide presents detailed illustrations and flowcharts to clarify the interactions between the pathological and physiological processes of sinusitis and illustrate current treatment practices.

Alan B. Weitberg, MD, and a panel of internationally recognized basic scientists and clinicians present a comprehensive discussion of lung cancer, including a practice-oriented review of its diagnosis, evaluation, and treatment. The contributors offer not only an understandable description of its molecular origins-an essential key to developing future therapies and preventive measures-but also rigorously discuss well-tested approaches, as well as those that are currently being evaluated for future use in both the laboratory and clinic. The book also elucidates the creation and effective deployment of treatment guidelines introduced by third party payers to improve clinical outcomes, even while lowering healthcare costs.

Providing a solid foundation for specialists in asthma treatment and control, this guide illustrates the importance of asthma monitoring practices for up-to-date assessments of disease levels in specific population groups; the identification of social, geographical, and environmental factors that may influence the development of asthma; and the design of improved and cost-effective prevention and management strategies for optimal patient care.

The book presents a comprehensive overview of the various disease processes affecting the chest and related abnormalities. It discusses biopsy and bronchography, as well as a variety of imaging techniques including radiography, fluoroscopy, tomography, and ultrasound.

Written by world authorities, this reference explores the utilization and advancement of state-of-the-art imaging modalities for the analysis of pulmonary function-providing an up-to-date and global perspective of imaging applications with detailed contributions from experts in Europe, North America, Japan, and Australia.

Emphasizing the impact of air toxins and contaminants on human health, this Second Edition examines the latest research from the epidemiology to the cellular mechanisms underlying cardiopulmonary responses to air pollution. This guide offers chapters that address the basic biology, techniques, and clinical practices used to monitor and assess acute and chronic pollutant responses; the effects of specific air toxins and contaminants on various populations chronically exposed to these compounds; and the complex issues associated with translating science to public health policy. This Second Edition offers a current and timely review of the effects of ambient air pollution on the human cardiopulmonary system provides new chapters on particulate matter (PM) air pollution, including particulate dosimetry of the respiratory system, genetic factors in the cardiopulmonary response to PM, PM-induced airway remodeling, and combustion emissions and their relation to cancer furnishes sections by chapter contributors with in-depth expertise in various areas of indoor and outdoor air pollution research maintains a balance between traditional topics and the review of current information showcasing the growing interest in the neuronal and cardiovascular effects that result from the exposure of human populations to PM air pollution crosses several scientific disciplines including epidemiology, toxicology, physiology, and public health presents the evolution of federal legislation and standards for air pollution emissions including the scientific rationale for these regulations

The only source to describe the lung surfactant as a complex membranous system, this guide analyzes lung surfactant function from the aspects of molecular biology, biophysics, membrane science, and surface and interface analysis and reviews the latest basic and clinical issues relating to lung disease and (dys)function.

Selected as a Doody's Core Title for 2022! Lippincott (R) Connect Featured Title Purchase the new print edition of this Lippincott (R) Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. Reflecting the trusted expertise of Dr. John B. West and Dr. Andrew M. Luks, West's Pulmonary Pathophysiology: The Essentials, Tenth Edition offers accessible explanations of disease processes that affect the respiratory system. This best-selling companion to West's Respiratory Physiology: The Essentials, 11th Edition, has served generations of students and practitioners who work with respiratory patients, presenting vital knowledge in a concise, straightforward manner that's easy to understand. Building on this legacy of success, the tenth edition is updated throughout with the latest clinical perspectives, new images, clinical vignettes, and enhanced USMLE-style review questions to help students excel in today's changing healthcare practice. UPDATED! Clinical Vignettes with open-ended questions demonstrate the real-world application of basic science and strengthen students' self-assessment. UPDATED! Radiographs, CT images, and color histopathologic sections clarify diagnostic and therapeutic approaches. UPDATED! USMLE-style multiple-choice questions, with answers, at the end of each chapter reveal areas requiring further study and boost students' test-taking confidence. Clinical features/notes boxes provide efficient, bulleted review for key diseases. End-of-chapter Key Concepts reviews reinforce essential chapter information at a glance. Appendices provide fast access to symbols, units, and normal values; further readings; and answers to multiple-choice and Clinical Vignette questions. Online video lectures, available via YouTube, engage students in the material and clarify challenging textbook concepts. Lippincott (R) Connect features: Full access to the digital version of the book with the ability to highlight and take notes on key passages for a more personal, efficient study experience. Carefully curated resources, such as interactive diagrams, audio and video tutorials, and self-assessment, all designed to facilitate further comprehension. Lippincott (R) Connect also allows users to create Study Collections to further personalize the study experience. With Study Collections you can: Pool content from books across your entire library into self-created Study Collections based on discipline, procedure, organ, concept or other topics. Display related text passages, video clips and self-assessment questions from each book (if available) for efficient absorption of material. Annotate and highlight key content for easy access later. Navigate seamlessly between book chapters, sections, self-assessments, notes and highlights in a single view/page.

During the past decades, "Dynamics of the singing voice" has successfully been established as a reference text for teachers of singing, singers, choral conductors and organists, speech and voice therapists, laryngologists and other health professionals, psychologists and those in linguistics. It discusses the physiological, psychological, musical and emotional aspects of the voice, particularly as they relate to singing but also to speaking. The book provides a greater understanding of how the voice works and the many factors involved in singing as well as an objective discussion of singing without reference to specific techniques.

In this fifth edition, the author has now updated and rearranged the content. Furthermore she has added a new chapter on vocal pedagogic aspects in order to meet the requirements of the art of singing of the 21st century. Thus this new book provides the reader with the established concepts in combination with the latest knowledge about modern approaches to the singing voice.

Many international experts collaborated in creating this groundbreaking work, a principal-coding system, and in developing reference films and imaging parameters for the" "International Classification of HRCT for Occupational and Environmental Respiratory Diseases. The book is an authoritative guide to the recognition of dust diseases of the lung, using radiological imaging techniques, with special emphasis on high-resolution computerized tomography (CT). The classification is a powerful, essential tool for recording patient data on CT in a globally standardized semiquantitative way. The system is also applicable to surveillance and screening for occupational and environmental respiratory diseases. The book is a valuable resource not only for radiologists but for all who work in occupational medicine and public health.

This text analyses the pathophysiology, diagnosis, treatment and control of respiratory disorders in the newborn infant. It explores the mechanisms, patterns and factors influencing respiratory activity and dysfunction, as well as the aetiology, management and evaluation of conditions such as respiratory distress syndrome, bronchopulmonary dysplasia, airway disorders, and congenital hypoventilation syndromes.