This invaluable little pocketbook takes the reader through the basics of chest X-ray examination and interpretation. It covers the range of conditions clinicians are likely to encounter on the wards, and guides the reader through the diagnostic process based on the appearance of the abnormality shown. Suitable for medical students, junior doctors and other health professionals who interpret chest X-rays, including radiographers, nurses and physiotherapists, this text is the ideal solution to increasing your skills and boosting your confidence in using chest X-rays for diagnosis and management. Chest X-Ray Made Easy has garnered international praise as the ideal quick and simple guide to understanding chest X-rays. Concise and succinct - makes interpretation of chest X-rays as simple as possible Comprehensive but easy to understand Specifically designed for junior doctors and students New chapter on what and when to request, and how to do that New images throughout, including obvious and subtle examples of abnormalities Includes CT images and how they correlate with chest X-rays Sections on radiation doses and indications for chest X-rays Sections on chest X-ray appearances in COVID-19 Updated section on imaging in pregnancy Features interpretation of placement of lines, tubes, and of complications Quiz section to test knowledge Established title that is trusted internationally

Respiratory Neurobiology: Physiology and Clinical Disorders, Part Two, Volume 189 is one of two volumes on the neurology of breathing. This volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases, while volume one focuses on the neurophysiology of breathing.

Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.

This volume provides a comprehensive and multi-disciplinary overview of the aging lung, written by the main researchers in the field. Current physiological, cellular and molecular understanding of how the lungs age and the relationship to age-associated lung diseases will be presented. The contents are aimed at a broad audience of scientists and clinicians with an interest in the respiratory system, pathogenesis of age-associated lung diseases and clinical implications.

Mitochondria, often referred to as the "powerhouses" of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.

Bundled with Lippincott® Connect, The Vascular System is more informative and approachable than ever. By using multimedia content and customizable assignments, this edition strengthens comprehension and prepares you for success in your course. Part of the highly regarded Diagnostic Medical Sonography series, Ann Marie Kupinski’s The Vascular System, 3rd Edition, thoroughly covers the core content students need to master in today’s rigorous sonography programs. Careful, collaborative editing ensures consistency across all three titles in this series: The Vascular System, Abdomen and Superficial Structures, and Obstetrics and Gynecology, providing the right content at the right level for both students and instructors.  Features up-to-date sonograms and relevant content throughout, including new coverage of ergonomics  Reflects today’s best practices with up-to-date coverage of diagnostic criteria  Provides key terms for quick reference, pathology boxes with tables of relevant pathologies, a complete glossary to help students master vocabulary of the sonography profession, and updated references that reflect the latest research in the field    Student ancillaries include: self-assessment questions • videos • internet resources  Instructor ancillaries include: eBook  • PowerPoint presentations • image bank • syllabus conversion guide    Also available: Workbook for Diagnostic Medical Sonography-The Vascular System, 3rd Edition, ISBN 978-1-9751-7707-2  This hands-on, full-color workbook (available separately for each series title) provides a variety of custom-designed exercises to help students master each objective and get the most out of their study time. Diagnostic Medical Sonography: The Vascular System, 3rd Edition, is now available with Lippincott® Connect! Lippincott® Connect enables you to personalize your teaching and enhance your students’ course experience in a customizable, all-in-one learning solution combining assessment, multimedia content, and an interactive eBook. Instructors can create assignments, assess students’ knowledge, and track their progress. Students maximize efficiency through valuable feedback and remediation. Key performance insights are reported in a user-friendly dashboard that allows instructors and students to tailor their teaching and learning experiences.  If you would like to use Diagnostic Medical Sonography: The Vascular System, 3rd Edition, in your course, please contact [email protected].    Enrich Your eBook Reading Experience  Read directly on your preferred device(s), such as computer, tablet, or smartphone.  Easily convert to audiobook, powering your content with natural language text-to-speech.  Lippincott® Connect enhances your student experience in an all-in-one learning solution combining an interactive eBook, multimedia content, and assessment. Instructors can customize the course, create assignments, and track your progress. Students maximize efficiency through valuable feedback and remediation. Key performance insights are reported in a user-friendly dashboard that allows you to tailor your learning experiences.

This book provides a comprehensive overview of how to use MRI for the imaging of lung disease. Special emphasis is placed on routine applications and the clinical impact of MRI in each setting. In addition, current technological developments are reviewed and information presented on dedicated applications of MRI in preclinical and translational research, clinical trials, and specialized institutions. During the past two decades, significant advances in the technology have enabled MRI to enter and mature in the clinical arena of chest imaging. Standard protocols are now readily available on MR scanners, and MRI is recommended as the first- or second-line imaging modality for a variety of lung diseases, not limited to cystic fibrosis, pulmonary hypertension, and lung cancer. The benefits and added value of MRI originate from its ability to both visualize lung structure and provide information on different aspects of lung function, such as perfusion, respiratory motion, ventilation, and gas exchange. On this basis, novel quantitative surrogates for lung function and therapy control (imaging biomarkers) are generated. The second edition of MRI of the Lung has been fully updated to take account of recent advances. It is written by an internationally balanced team of renowned authors representing all major groups in the field.

Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Therefore, nanoparticles, compared to larger (e.g., micrometer) particles, are considered to behave differently when they interact with cells. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery provides a better understanding of how inhaled nanoparticles behave in the human lungs and body. Featuring contributions from renowned subject-matter experts, this authoritative text describes the sequence of events that nanoparticles encounter in the lungs when moving from the air into the bloodstream. This includes deposition, interactions with the alveolar surface and epithelium, translocation across the air-blood tissue barrier, and accumulation in the body. In addition, the book addresses practical considerations for drug delivery to the respiratory tract, drug and gene delivery in the lungs, and bio-nanocapsules. It considers the physicochemical, colloidal, and transport properties of nanoparticles, and presents cutting-edge research on special issues such as dosimetry for in vitro nanotoxicology, nanoparticle deposition in the developing lungs, and the potential for nose-to-brain delivery of drugs. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery offers the most updated and comprehensive knowledge of the risks and benefits associated with nanoparticle inhalation-to protect humans from any harmful effects and to explore the utility of nanoparticles as drug delivery carriers.

This is the only book dedicated solely to frontal sinus disorders. It is a richly illustrated and comprehensive mine of information on the anatomy and management of these disorders. This updated second edition offers much new information. Additional topics include balloon dilation, frontal surgery as part of skull base surgery, and advances in endoscopic techniques and tools that have occurred since 2004 and have made open osteoplastic procedures almost obsolete. The anatomy and surgery of the supraorbital ethmoid cell and its significance in the pathology of frontal sinus disease are also covered. Throughout the book, particularly important areas of text are highlighted and core messages, emphasized. Videos of described procedures are available online.

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems

"Pulmonary Sarcoidosis: A Guide for the Practicing Clinician" is a valuable resource for clinicians of varied disciplines concerning the care of the sarcoidosis patient. Sarcoidosis is a multi-system disorder and represents a major challenge to physicians. Although any organ may be involved with sarcoidosis, the lung is the most common organ affected. Chapters are written by distinguished authors who have extensive experience in caring for these patients. Detailed figures and tables are provided to guide the practicing clinician through all aspects of the condition, from clinical manifestations to treatment options. "Pulmonary Sarcoidosis: A Guide for the Practicing Clinician" is fully comprehensive and evidence-based and will be an essential addition to the bookshelves of all whose practice involves the care and treatment of patients with sarcoidosis.

Respiration is an area of the medical study that undergoes fast developments. A better understanding of the neural and cellular mechanisms underlying respiratory disorders and lung function is essential for the evidence-based pharmacotherapy and for optimizing the patient care and prophylactic measures to improve the health and quality of life. This comprehensive book is a blend of basic and clinical research. The book is thought to promote the translation of science into clinical practice. The book presents an update on the areas of current research and clinical interest in the neurobiology of the respiratory system. Recent innovations in detection and management of respiratory diseases are described. The book will be a base of reference in the field of respiration for years to come and a source of future research ideas. This book is a required text for respiratory scientists, neuropathologists, and for clinicians searching for 'bench to bedside' treatments of lung diseases.

This Workbook is designed to reinforce the essential concepts presented in Clinical Application of Mechanical Ventilation, and give learners practice with questions written in NRBC format. With a concise and easy-to-read approach, the new edition of this book integrates the essential concepts of respiratory physiology with the clinical application of mechanical ventilation. Extensive coverage of airway management and weaning criteria, and a concise view of pharmacotherapy for mechanical ventilation are included. This edition features new material on special procedures in mechanical ventilation, chest tubes and placement, proportional pressure support, airway management, and ventilator waveform analysis.

The book blends basic and clinical research on respiratory carcinogensis. The contributions tackle a variety of respiratory-related cancers, notably non-small cell lung carcinoma, pleural mesothelioma, mediastinal tumors, or larynx cancer. The focus is on the search for novel molecular markers, derived from easily accessible tissues in clinical settings, such as the serum or bronchoalveolar lavage fluid, which could help diagnose cancer at an early stage and have a prognostic therapeutic value. The transcriptional mechanisms which endow cells with the capacity for unlimited proliferation are considered, with silencing of tumor suppressor genes is the exemplar. Chapters provide insight into a variety of cancer-related disorders of the respiratory tract, novel ways of differential diagnosis and treatment. The aim is to bring the current clinical procedures into alignment with the latest basic research findings. The book is a text for respiratory researchers, clinicians, and pathologists.

The COPD chart presents a detailed overview of the symptoms and causes of Chronic Obstructive Pulmonary Disorder (COPD). Sections help explain the two related respiratory diseases that constitute COPD - emphysema and chronic bronchitis. Heavy cover stock with protective varnish for durability.

Bronchitis and emphysema affect some three million people in the UK, and kill 30,000 people each year. They account for more loss of time from work than any other form of illness, and are usually caused by smoking, which leads to inflammation of the bronchi. As the lungs become increasingly damaged, shortness of breath develops even on moderate exertion, such as climbing stairs. As the condition worsens, simple tasks such as washing or shaving cause marked shortness of breath, and eventually fighting for breath occurs even at rest. The condition cannot be cured. However, further deterioration can be prevented, and this new edition brings us up to date with changes in treatment, though stopping smoking is still key. Difficulty in breathing can be eased by using inhalers or nebulisers which deliver drugs that open up the airways called bronchodilators (eg Ventolin'). Inhaled steroids (eg Becotide') are useful in reducing inflammation of the air tubes. Many people need to have oxygen several times a day, and dust, fumes and pollution should be avoided. Lifestyle changes may also help, such as losing weight and taking exercise.

An intensive-care doctor reveals the long-term problems caused by ICUs, and how these can be prevented. Thousands of people are admitted to intensive-care units (ICUs) every day, and this is only increasing with the Covid-19 pandemic. Most of these admissions will be sudden, unexpected, and harrowing - an experience that can alter patients and their families in physical, emotional, and spiritual ways, with effects that endure for years. But there is hope. Dr Ely is a leading ICU doctor. His unconventional methods minimise patients being harmed by the cutting-edge technologies that are saving their lives; post-intensive care syndrome (PICS) is a well-established complication that millions of ICU survivors battle, which Dr Ely aims to eradicate. His cutting-edge studies have convinced doctors around the world to change their ICU practices for the better. Through captivating stories, Dr Ely shows how he and colleagues from around the world have re-introduced humanity into the ICU, creating pathways that bring hope and healing to healthcare. This is the future of medicine, and is a must-read for healthcare professionals, patients, and their families.

Master the equipment, devices, and techniques used in respiratory therapy! Mosby's Respiratory Care Equipment, 11th Edition provides a comprehensive guide to treating patients with cardiopulmonary dysfunction. Using a how-to approach, this text helps you learn to identify and select equipment, understand its operation, and apply your knowledge to clinical practice. It also discusses assessment, testing, protocols, and troubleshooting of the devices used in airway management. Written by noted educator J. M. Cairo and a team of expert contributors, this leading text provides the skills that will help you breathe easier as you prepare for NBRC examinations. Unique! Clinical approach provides a "how to" approach to identifying equipment, understanding how it works, and applying the information in clinical practice. Unique! Organization of ventilators by application area and manufacturer makes it easier to learn, review, and locate ventilator information. Unique! Infection Control chapter reviews microbiology and infection control, a topic that RTs must understand to prevent healthcare-associated infections, and discusses infection control in mass casualty situations. Unique! Clinical Scenario boxes address problems that may be encountered during actual use of equipment and raise clinically relevant questions, with suggested answers on the Evolve companion website. Learning features include chapter outlines, learning objectives, key terms, chapter introductions, and bulleted key point summaries to identify and reinforce the most important material in each chapter. Chapter review questions at the end of every chapter reinforce your comprehension, using NBRC-style multiple-choice or critical-thinking questions to match the types of questions covered on the NBRC exams. Unique! Historical Notes boxes highlight clinically relevant and valuable historical information on respiratory care equipment. Excerpts of Clinical Practice Guidelines (CPGs), statements of care developed by the AARC, provide important information regarding indications/contraindications, hazards and complications, assessment of need, assessment of outcome, and monitoring. Glossary of key terms is listed in the back of the book for quick reference. NEW! Updated clinical scenarios are added throughout the text, which incorporate clinical practice guidelines (AARC, AECC, CCM) and reflect NBRC exam outlines. NEW! Updated end-of-chapter questions include additional clinical data, which also incorporate clinical practice guidelines (AARC, AECC, CCM) and reflect NBRC exam outlines. NEW! Coverage of infant and pediatric ventilators is now included in the Mechanical Ventilators: General Use Devices chapter. NEW! Updated Transport, Home Care, and Noninvasive Devices chapter includes the use of mechanical ventilators in alternative sites, e.g., air transport and long-term acute care (LTAC) facilities.

Recognizing the increasing importance of ultrasonography in the evaluation and management of patients across a range of medical disciplines, this guide provides illustrative instruction on the performance and interpretation of ultrasound examinations in emergency, critical care, hospital, and outpatient settings.

Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies. The final integrated strategies section draws the major points from the applications for disease targets and drug products.

The use of stem cells to help with lung regeneration and repair is a novel therapy which could help phase out the need for conventional surgical or pharmacological approaches currently employed to treat diseases of the lung or other organs. The present book explores all avenues of this new form of medical care, moving swiftly, but in depth, from the basic science of lung development, to the analyses of different stem cell types available for regeneration and on to the application of this knowledge base in initial clinical trials. In this volume a stellar group of researchers converge, from different angles, to help towards clarifying the basic mechanisms of lung repair. These range from basic concepts of regeneration and lung development, the analyses of a variety of cell types that may be involved in lung repair, to ways of creating complex lung structures, including artificial and bioartificial lungs. The book offers an insight into repair mechanisms of the diseased lung, the role of specific lung niches and provides information on initial clinical trials as well as the use of stem cells as vehicles for gene therapy. Ingenious technological aspects of assessing stem cell engraftment of stem cell bioprocessing are also included in this volume.

We start life with a breath, and the process continues automatically for the rest of our lives. Because breathing continues on its own, without our awareness, it does not necessarily mean that it is always functioning for optimum mental and physical health. The opposite is true often. The problem with breathing is that it seems so easy and natural that we rarely give it a second thought. We breathe: we inhale, we exhale. What could be simpler? But behind that simple act lies a process that affects us profoundly. It affects the way we think and feel, the quality of what we create, and how we function in our daily life. Breathing affects our psychological and physiological states, while our psychological states affect the pattern of our breathing. For example, when anxious, we tend to hold our breath and speak at the end of inspiration in a high-pitched voice. Depressed people tend to sigh and speak at the end of expiration in a low-toned voice. A child having a temper tantrum holds his or her breath until blue in the face. Hyperven tilation causes not only anxiety but also such a variety of symptoms that patients can go from one specialty department to another until a wise clinician spots the abnormal breathing pattern and the patient is successfully trained to shift from maladaptive to normal breathing behavior."

Sleep Apnea: Implications in Cardiovascular and Cerebrovascular Disease specifically addresses the cardiovascular and cerebrovascular consequences of sleep apnea and is geared toward a broad readership of physicians that will ultimately aid patients suffering from sleep apnea.

The Second Edition ensures that there is a critical synthesis of existing literature and new information, linking sleep apnea to the major disease burdens faced by developed and developing nations. This synthesis includes both new basic and epidemiological data and published clinical trials linking sleep apnea to:

• inflammation
• the metabolic syndrome
• stroke
• hypertension and heart failure

Written by internationally recognized experts, Pulmonary Hypertension bridges the gap between pulmonology and cardiology to provide clinicians in both disciplines with knowledge of the signs, symptoms, diagnosis, and pharmacologic and surgical treatments for pulmonary hypertension (PH). Through the use of clinical trials, this ground-breaking text supplies a comprehensive review of both the primary and secondary clinical and investigative aspects of this condition.

Discussing controversies and concepts in PH diagnosis and management, this guide explores:

• classification and epidemiology, pathology, pathogenesis, genetics, and diagnosis of PH
• causes of the condition, such as idiopathic pulmonary arterial hypertension (IPAH)
• PAH-complicating connective tissue diseases (CTD), congenital heart diseases, human immunodeficiency virus (HIV), and other disorders
• the mechanisms, toxicities, and efficacy of therapeutic agents
• the role of combination therapies, novel agents, and future directions
• PH in specific patient populations such as pregnant and critically-ill patients in the ICU

This volume is dedicated to multidisciplinary research at the interface between basic biomedicine and clinical practice. This book guides best practice in the diagnosis and therapy while dealing with difficult-to-treat disorders of yet unclear etiology. Chapters address such disorders as granulomatosis with polyangiitis causing autoimmune-related multiorgan inflammation of blood vessels, increasingly widespread allergy to peanuts, occupational exposure to zinc oxide, and immunogenic responses to pneumococcal and influenza vaccination underlying their preventive effectiveness. Other hot issues deal with the proper use of fluid therapy in the perioperative period and a cognitive decline in lung transplant patients. A new physiotherapeutic approach of treating key myofascial trigger points in low-back pain appears highly beneficial in reducing patients' disability, advancing physiotherapy of this overwhelming condition. Finally, other chapters consider ways to streamline medical management to increase the number of physicians and their availability for patients, a particularly sensitive issue in the current COVID-19 pandemic. The dissemination of clinical knowledge about high-risk and hardly controllable conditions is an inalienable part of progress in medical practice. The book is a resource for clinical specialists, general practitioners, and allied healthcare professionals.