This book describes various aspects of current scientific interest in clinical developments and management of pulmonary pathologies. Non-communicable and communicable disorders are tackled. Chronic disorders of an inflammatory background, such as COPD and asthma, often overlapping, diagnostically and therapeutically misguided and always difficult to manage, are in focus due to an increasing prevalence across the age range. The authors dwell on the disease management, exacerbations, care and therapy, taking into account all too often overlooked psychosomatic determinants. Novel markers of pulmonary sarcoidosis, also an inflammatory disease, albeit of unknown etiology, are described. The outstanding lung images of cystic fibrosis are presented in another chapter. Finally, there are reports on the extent of the influenza scourge in Poland during the past 2016/2017 epidemic season. The book is addressed to clinicians, family physicians, medical scholars, and all professionals engaged in the preservation of respiratory health.

This book discusses normal sex-related differences in lung structure and function and the role these differences play in lung disease. New research on the effects of sex hormone signaling on specific cell types of the lung has begun to reveal how these hormones may drive or prevent lung disease. Expertly written chapters examine the effects of sex hormones on normal pulmonary structure and function, hormone signaling in lung health, and specific diseases such as chronic obstructive pulmonary disease, asthma, pulmonary hypertension, and lung cancer. Gender, Sex Hormones, and Respiratory Disease: A Comprehensive Guide focuses on our current understanding and the gaps in research, with suggestions for future directions and implications for therapy. This book is a useful reference for pulmonologists and researchers and will prompt further inquiry aimed at improving overall lung health.

Respiratory function is a major determinant of the overall quality of health and well-being of an individual. This book runs the gamut of chapters devoted to chronic cough-related conditions in children and adults, health care quality and safety, environmental pollution health effects, efficiency of therapeutic approaches and a mutual dependence of respiratory and non-respiratory illnesses. An integrated approach to the investigation and treatment of sleep disordered breathing as well as the use of new and more efficient diagnostic strategies for pleural tuberculosis are presented. Chapters focus on translating science into practice, with an eye on presymptomatic identification of serious ailments for which there could be more effective therapy, leading to improved general health outcomes. This book includes chapters about disorders which will be of interest to clinicians, family practitioners and medical researchers.

The impairment of lung function caused by environmental exposure to pollutants and toxicants is a rising health problem, particularly in highly industrialized parts of the world. The problem is urgently calling for the development of new methodologies to assess both the level of elemental exposure and the effects for quality of health and longevity. This volume provides state-of-the-art information about the recent advances in occupational and non-occupational pollutant-related disorders of the respiratory tract, and the assessment of a threat they pose for the health-span. Heavy traffic-related air pollution, unnoticeable but salient health detriment, is dealt with at length.

This comprehensive book thoroughly covers the spectrum of rhinitis conditions and related comorbidities. Rhinitis and Related Upper Respiratory Conditions is a unique resource that delivers essential clinical information, addressing the varying patient populations which might be encountered in different types of clinical settings. Chapters range from topics such as pediatric, adult, geriatric, and occupational rhinitis, while also covering the full array of rhinitis subtypes and their complications. Later chapters address secondary causes of rhinitis such as systemic diseases manifesting as rhinitis, drug-induced rhinitis, and CSF leak. Written by experts in the field, every chapter is structured to contain clinical cases which illustrate the typical patient presentation, and their diagnostic work-up and treatment, providing the knowledge needed to further improve diagnosis and care for the patient with rhinitis. Rhinitis and Related Upper Respiratory Conditions is an ideal resource for allergists, primary care physicians, and health care extenders, to help them recognize and further improve care of patients with rhinitis.

Presenting the basic concepts and clinical implications of respiratory infection, with special emphasis on the role of the immune system, the field's leading researchers contribute detailed chapters on most of the major pathogenic and opportunistic bacteria, fungi, and viruses. Their work will stimulate new research by microbiologists and immunologists, teach clinicians the interaction between microorganisms and the host, and provide health professionals with information necessary to evaluate public health procedures.

This book addresses several burning issues concerning diseases involving the lungs and respiratory tract. It discusses the epidemiology, mechanisms, prevention, and diagnosis of chest conditions such as chronic obstructive pulmonary disease, sleep apnea and respiratory infections. Further, it examines the intertwined connection between oxidative stress, cardiovascular disorders such as hypertension, and the occurrence and course of obstructive sleep apnea. It also provides pulmonologists with valuable information on the diagnosis and treatment of patients with severe airway obstruction or respiratory tract infections. Other topics covered include viral infections of the airways, such as influenza, particularly in high-risk groups like pediatric populations, as well as psychosocial aspects, e.g., quality of life in lung cancer patients. Combining basic science and clinical practice, the articles provide key insights and highlight the areas of still limited understanding of disease processes. Stimulating new directions in clinical practice, this collection of articles is intended for respiratory physicians, clinical experts, family practitioners, and all allied healthcare professionals.

This book examines a range of contemporary ideas and arguments concerning the core yet unsettled clinical issues. Important aspects of pulmonary disorders are tackled such as occupational and environmental respiratory health hazards, the role of vitamin D supplementation in airway allergy, or nutritional aspects of care for lung cancer patients. Metabolic disorders affecting the processes of atherogenesis and systemic inflammation also are tackled. Attention is directed to rare but severe pediatric disease entities. Articles give readers practice at analyzing clinical data. The practical insights emphasize the role of science in transforming biomedical knowledge and care. This volume will be essential reading for clinicians, researchers, and other healthcare professionals engaged in effective patient care and therapy.

This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early severe sepsis. Care of these patients and clinical conditions can be quite complex, and materials are collected from the most current, evidence-based resources. Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis. This review summarizes the evidence for the international consensus guidelines for the identification and management of sepsis. The latter part of this book reviews emerging concepts and approaches in the diagnosis and management of sepsis that may significantly reduce mortality in the future. Sepsis: Pathophysiology, Definitions and the Challenge of Bedside Management represents a collaboration between authors drawn from a variety of disciplines and contributions from basic scientists and highly recognized clinical opinion leaders with expertise in clinical trials.

Master the principles and skills of respiratory care for neonates, infants, and children! Neonatal and Pediatric Respiratory Care, 6th Edition provides a solid foundation in the assessment and treatment of respiratory disorders in children. Clear, full-color coverage simplifies the concepts of respiratory care while emphasizing clinical application. Reflecting the changing face of this profession, this edition unpacks care strategies with coverage of the newest treatment algorithms, interventions, mechanical ventilation technologies, and more. From an expert team of contributors led by Brian K. Walsh, an experienced respiratory therapist and researcher, this text is an excellent study tool for the NBRC's Neonatal/Pediatric Specialty examination. Authoritative, evidence-based content covers all of the major topics of respiratory care for neonates, infants, and children, including both theory and application, with an emphasis on an entry-level BS degree. Nearly 500 full-color illustrations - plus clear tables and graphs - make it easier to understand key concepts. Case studies include a brief patient history and questions for each, showing how concepts apply to the more difficult areas of care for neonatal and pediatric disorders. Complete test preparation is provided through coverage of all the content in the matrix for the 2020 NBRC neonatal/pediatric specialty (NPS) credentialing exam. Learning Objectives at the beginning of each chapter break down key content into measurable behaviors, criteria, and conditions. Key Points at the end of each chapter summarize the more important information in a bulleted format. Assessment Questions at the end of each chapter are written in the NBRC multiple-choice style as found on the Neonatal/Pediatric Specialty (NPS) exam, helping you become familiar with the NBRC testing format. Glossary makes it easy to find definitions of all of the book's key terminology. Answers to assessment and case study questions are provided on the Evolve website. NEW! Logical, easy-to-use organization divides the content into three sections of 1) Neonatal, 2) Pediatrics, and 3) Neonatal and Pediatric combined, mirroring the academic approach of most respiratory care programs. NEW! Updated content reflects the new matrix for the 2020 NBRC Neonatal/Pediatric Specialty (NPS) exam. NEW! Assessment Questions at the end of each chapter are updated to reflect the changes to the 2020 NBRC exam. NEW! Additional treatment algorithms of care are added to relevant chapters.

Mustard Lung: Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients brings together the details regarding pathophysiology, medication, and protective issues to provide a comprehensive look at health problems associated with sulfur mustard injury. It provides a bench-to-bedside look at the long term complications of vesicant exposure in humans as well as how mustard gas exposure affects lung function. By providing guidelines and approaches for the diagnosis, pathogenesis, and treatment of SM injury cases, this book is helpful for a wide range of medical researchers and clinicians. For decades, chemical respiratory disorders were diagnosed and managed traditionally similar to other chronic respiratory diseases. However, the exact nature of chemical respiratory disorders is different and needs to be treated as such.

Use this all-in-one reference in the lab - and to prepare for PFT credentialing exams! Ruppel's Manual of Pulmonary Function Testing, 12th Edition provides comprehensive coverage of common pulmonary function tests, testing techniques, and the pathophysiology that may be evaluated by each test. It also includes information on equipment, measurement software, reference values, and quality assurance, so you can develop the testing skills you need to find and assess lung abnormalities and conditions such as asthma, COPD, and emphysema. Written by Carl D. Mottram, a well-known expert in pulmonary function procedures, this bestselling guide helps you get accurate test results every time. Entry- and Advanced-Level objectives prepare you for success on the NBRC's Pulmonary Function Technologist credentialing examinations and follow the content guidelines of the CPFT and RPFT exam matrices from the National Board for Respiratory Care. How To boxes provide step-by-step guidelines to performing pulmonary function tests, taking the guesswork out of completing accurate and result-producing tests. Case studies provide problem-solving challenges for real-life patient scenarios, including each case history, PFT testing results, a technologist's comments, and questions and answers. PFT Tips highlight and reinforce the most important pulmonary function testing information in every chapter. Convenient study features include key terms, chapter outlines, learning objectives, chapter summary points, suggested readings, a glossary, and self-assessment questions. Authoritative, all-in-one resource eliminates the need to search for information in other sources. Criteria for acceptability and repeatability are included in each test section, as well as interpretive strategies to help you adhere to recognized testing standards. NEW! Indications for Pulmonary Function Testing chapter Includes updates in alignment with the 2019 ATS-ERS Spirometry Standards. NEW! Spirometry chapter adds updated Information per the new 2019 ATS-ERS Spirometry Technical Standard. NEW! Diffusing Capacity Tests chapter is aligned with the 2014 ERS-ATS Technical Standard and the 2017 Global Lung Initiative (GLI) DLCO reference set. NEW! Bronchoprovocation Challenge Testing chapter is updated with the 2017 ERS Methacholine Challenge Technical Standard and 2018 ERS Indirect Bronchial Challenge Testing (e.g., mannitol, exercise, hyperventilation, cold air). NEW! Specialized Test Regimens chapter includes 2018 ATS Reference Values in Children. NEW! Pulmonary Function Testing Equipment chapter is updated with new equipment and vendors. NEW! Quality Systems in the Pulmonary Function Laboratory chapter is updated with the newest version of the Clinical and Laboratory Standards Institutes (CLSI) Quality Management System (QMS01), which is the basis for any laboratory quality program, and a new table of recommended target CVs for Biological control (BioQC). NEW! Reference Values and Interpretation Strategies chapter adds new GLI (Global Lung Function Initiative) reference sets for Diffusing of the Lung and Lungs Volumes.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Vitamin D deficiency is a worldwide problem and many associations with diseases are being discovered. Recently, there has been an interest in the role that vitamin D plays in the inception and progression of lung disease. Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders. Divided into three sections, the first section of the book delivers a review of how vitamin D deficiency emerged in human populations, and gives a perspective on how humans evolved to maximize the efficiency of production of vitamin D. The second section of the book reviews aspects of vitamin D mechanisms on different immune cells, lung tissue, and genetics that have potential impact on lung disease. The third section follows with chapters on associations of vitamin D with the risk for viral infections, asthma and allergies, chronic obstructive pulmonary disease, cystic fibrosis, tuberculosis, and finally, lung cancer with an emphasis on ongoing research and clinical issues and needs for future research in each field. Written by an international group of expert authors, Vitamin D and the Lung: Mechanisms and Disease Associations is an essential text for researchers in the respiratory field and practicing clinicians including internists, pulmonologists, and primary care personnel.

Nursing Clinics of North America Nursing Clinics of North America

It is commonly accepted that "exercise is good for children" but, considering the number of children worldwide exercising, we know comparatively little, compared to adults, about how specific mechanisms influence health and sports performance. There are considerable obstacles that challenge the progress of paediatric research, not least in relation to ethical and methodological considerations. Therefore, advances in the science and clinical application of paediatric exercise physiology, psychology and biomechanics have not reached their potential. Paediatric clinical exercise physiology has application to the role of exercise in the assessment and treatment of paediatric chronic diseases, the utilization of physical activity in preventing illness and enhancing wellbeing and can enhance our understanding of how sports can be made safer and more enjoyable for our young athletes. Exercise and Respiratory Diseases in Paediatrics highlights research by various methodologies, including literature reviews, experimental research and innovations, applied to children and adolescents with respiratory diseases. Chronic conditions such as asthma, bronchiectasis (e.g., cystic fibrosis), and those associated with prematurity and medical complexity are worldwide health problems for young people and although management includes pharmaceutical medications, physiotherapy, nutritional and psychological support, exercise has a role in optimising multidisciplinary care. There has been unprecedented acceleration in new technologies and methodologies that promise to facilitate paediatric research and these are explained and discussed as future research directions. This is reading for post graduate students, researchers, academics and policy makers within the field of paediatric healthcare, physical activity, physiology and the related disciplines.

Key Features Comprehensive coverage of all aspects of work-related asthma, including historical aspects, epidemiology and risk factors, mechanisms and genetics, other types of work-related asthma conditions and variants, hypersensitivity pneumonitis, occupational urticaria and dermatitis Assessment of the worker and workplace along with management of the worker, prevention and medicolegal aspects Of interest not only to pulmonologists, but also for industrial hygienists, researchers, lawyers and other health professionals in the field of work-related conditions Detailed information about specific agents, including a variety of high- and low-molecular weight agents

Nutrition in Pediatric Pulmonary Disease is a much needed resource for practitioners that provides a basic understanding of nutrition and nutritional supplements; their impact on physiologic function and how this can be applied for general health maintenance as well as a supplemental treatment for pulmonary diseases. This book provides information on (1) basics of nutrition, supplements and herbs and how they influence physiology (2) their application and potential use for various pulmonary diseases along with evidence regarding efficacy and safety. Also examined are (3) how diet, dietary supplements and herbs are integrated together for treatment and prevention of pulmonary disease. Finally (4) several health promoting diets and their potential benefits to patients with pulmonary diseases will be discussed. Nutrition in Pediatric Pulmonary Disease is an excellent new resource for practicing physicians who are interested in incorporating more nutritional approaches to treating their patients.

Over the last decade the science and medicine of high altitude and hypoxia adaptation has seen great advances. "High Altitude: Human Adaptation to Hypoxia "addresses the challenges in dealing with the changes in human physiology and the particular medical conditions that arise from exposure to high altitude. In-depth and comprehensive chapters cover both the basic science and the clinical consequences of exposure to high altitude. Genetic, cellular, organ and whole body system responses to high altitudes are covered and chapters discuss these effects on a wide range of diseases. Expert authors provide insight into the care of patients with pre-existing medical conditions that fail in some cases to adapt as well as offer insights into how high altitude research can help critically ill patients. "High Altitude: Human Adaptation to Hypoxia" is an important new volume that offers a window into greater understanding and more successful treatment of hypoxic human diseases."

In 1882, Robert Koch discovered the TB bacillus, signaling a redirection of medical thinking from the trial and error guesswork of individual experience toward medical care based upon science. Professor Ellison uses the career of Edward Livingston Trudeau (1848-1915), a recognized leader in the American crusade against tuberculosis, to examine the development of medical science as a human process. Ellison asks how the germ theory influenced the thinking of physicians like Trudeau; how it affected the sanitorium treatment of patients, and even the development of laboratory studies. During Trudeau's lifetime, physicians confronted a killer disease with contradictory knowledge that was largely empirical, based on their clinical experience. Koch's discovery of the cause of tuberculosis raised the hope that a cure was within easy reach. But, in the end, a cure eluded Trudeau. Despite this, he adopted a method of caring for patients in the early stages of tuberculosis, he legitimated that system to the public, and he defended it before his fellow physicians. Trudeau's story has lessons for the way society looks at medicine specifically and all sciences in general. As such, this book will be of great interest to historians of medicine and science.

The Right Ventricle in Health and Disease provides a comprehensive and up-to-date database and collection of the available information which describes the structure and function of the normal right ventricle. The right ventricular performance and function reserve has now finally moved to the center of the stage as clinicians recognize that the drugs presently used to treat patients with severe pulmonary hypertension do not necessarily improve the performance of the right ventricle and because the survival depends on the right ventricular function that treatment strategies need to be developed to primarily protect the right ventricle from failing. In-depth chapters discuss right heart function and failure in patients with congenital heart diseases, review modern imaging techniques used to describe right ventricular form and function in patients with right heart failure (including cardiac MRI and PET scanning), describe ventricular interdependence: the left ventricle in pulmonary hypertension and discuss the concept of the sick lung circulation and its contribution to right heart failure. Treatment strategies of chronic right heart failure including drugs and mechanical devices are also discussed.

Quick, one-stop guide to neonatal resuscitation steps. Printed on flexible plastic with self-adhesive mounting strips. Size: 22" x 34

Organisms need to be able to maintain nearly constant internal environments in order to survive, grow and function effectively and efficiently. By maintaining homeostasis, humans remain healthy, strong and protected from the invasion of foreign organisms, such as viruses, bacteria and fungi. This practical pocket guide covers: * the anatomy and physiology of cardiovascular system vital signs * recognition of common arrhythmias and important skills for cardiovascular health cannulation and venepuncture * the anatomy and physiology of the respiratory system * skills related to addressing respiratory problems. This competency-based text covers relevant key concepts, anatomy and physiology, lifespan matters, assessment and nursing skills. To support your learning, it also includes learning outcomes, concept map summaries, activities, questions and scenarios with sample answers and critical reflection thinking points. Quick and easy to reference, this short, clinically-focused guide is ideal for use on placements or for revision. It is suitable for pre-registration nurses, students on the nursing associate programme and newly qualified nurses.

Reflecting recent major advances in the field of artificial intelligence, Developing the Digital Lung, From First Lung CT to Clinical AI, by Dr. John Newell, is your go-to reference for all aspects of applied artificial intelligence in lung disease development, including application to clinical medicine. It provides a unique overview of the field, beginning with a review of the origins of artificial intelligence in the mid-1970s and progressing to its application to clinical medicine in the early 2020s. Organized based on the four stages of development, this practical, easy-to-use resource helps you effectively apply artificial intelligences to lung imaging. Traces the development of precise quantitative CT of diffuse lung disease through the use of applied AI, leading to faster effective diagnosis of patients with lung disease. Reviews CT manufacturers, models and scanning protocol used to produce the 3D digital maps of the lungs. Discusses how the data processed by AI algorithms can produce measures of emphysema, air trapping, and airway wall thickening in subjects with COPD and measures of pulmonary fibrosis and traction bronchiectasis in idiopathic pulmonary fibrosis (IPF). Demonstrates the differences between reactive machine AI and limited memory AI methods. Includes comprehensive case studies and current information on cloud computing. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.