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Dendrimers in Nanomedicine - Concept, Theory and Regulatory Perspectives (Hardcover)
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Dendrimers in Nanomedicine - Concept, Theory and Regulatory Perspectives (Hardcover)
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Dendrimers, hyperbranched macromolecules, emerged just few decades
ago but show promising potential as drug delivery nanocarriers,
theranostic agents and gene vectors; in the pharmaceutical research
and innovation area as well as in other healthcare applications.
Although tremendous advancements have been made in dendrimer
chemistry and their applications since their emergence, the
synthesis, development and design of pure and safe dendrimer-based
products have been a major challenge in this area. This book,
edited by well-known researchers in the area of nanomaterials and
drug-based drug delivery applications, exhaustively covers the
nanotechnological aspects, concepts, properties, characterisation,
application, biofate and regulatory aspects of dendrimers. It
includes sixteen vivid chapters by renowned formulators,
researchers and academicians from all over the world, highlighting
their specialised areas of interest in the fields of chemistry,
biology, pharmacy and nanomedicine. Features: * Highlights
dendrimers' advancements in nanomedicine in the development of safe
healthcare and biotechnological products * Covers physicochemical
aspects, biofate, drug delivery aspects and gene therapy using
dendrimers * Covers biomedical application of dendrimers in the
field of biological sciences * Gives examples of dendrimer-guest
interaction chemistry Dendrimers in Nanomedicine: Concept, Theory
and Regulatory Perspectives provides the comprehensive overview of
the latest research efforts in designing, optimising, development
and scale-up of dendrimer-mediated delivery systems. It analyses
the key challenges of synthesis, design, molecular modelling,
fundamental concepts, drug delivery aspects, analytical tools and
biological fate as well as regulatory consideration to the
practical use of dendrimer application. Dr. Neelesh Kumar Mehra
Assistant Professor of Pharmaceutics in the Department of
Pharmaceutics at the National Institute of Pharmaceutical Education
& Research (NIPER), Hyderabad, India. He has authored more than
sixty peer-reviewed publications in highly reputed international
journals, as well as book chapters and contributions on two
patents. Dr. Mehra has 11 years of rich research and teaching
experience in the formulation and development of complex,
innovative biopharmaceutical products including micro- and
nanotechnologies for regulated markets. Dr. Keerti Jain Assistant
Professor of Pharmaceutics in the Department of Pharmaceutics,
NIPER, Raebareli, India. For more than 10 years, she has been
actively engaged in formulation and development of nanomedicines.
Dr. Jain has supervised masters and doctoral pharmaceutics students
in their research works which have been published in high quality,
good impact factor journals. She has also authored more than 60
international manuscripts in peer reviewed high impact journals. In
2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.
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