Current Status and Future Scope of Microbial Cellulases not only explores the present and future of cellulase production, it also compares solid state fermentation (SSF) and submerged fermentation (SMF) for cellulase production. Chapters explore bioprocess engineering, metabolic engineering and genetic engineering approaches for enhanced cellulase production, including the application of cellulase for biofuel production. This important resource presents current technical status and the future direction of advances in cellulase production, including application of cellulases in different sectors.

Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences brings together two very important fields in pharmaceutical sciences that have been mostly seen as diverging from each other: chemoinformatics and bioinformatics. As developing drugs is an expensive and lengthy process, technology can improve the cost, efficiency and speed at which new drugs can be discovered and tested. This book presents some of the growing advancements of technology in the field of drug development and how the computational approaches explained here can reduce the financial and experimental burden of the drug discovery process. This book will be useful to pharmaceutical science researchers and students who need basic knowledge of computational techniques relevant to their projects. Bioscientists, bioinformaticians, computational scientists, and other stakeholders from industry and academia will also find this book helpful.

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine.

The depletion of fossil fuels is a major issue in energy generation; hence, biomass and renewable energy sources, especially bioenergy, are the solution. The dependence on bioenergy has many benefits to mitigate environmental pollution. It is imperative that the global society adopts these alternative, sustainable energy sources in order to mitigate the constant growth of climate change. Biomass and Bioenergy Solutions for Climate Change Mitigation and Sustainability highlights the challenges of energy conservation and current scenarios of existing fossil fuel uses along with pollution potential of burning fossil fuel. It further promotes the inventory, assessment, and use of biomass, pollution control, and techniques. This book provides the solution for climate change, mitigation, and sustainability. Covering topics such as biofuel policies, economic considerations, and microalgae biofuels, this premier reference source is an essential resource for environmental scientists, environmental engineers, government officials, business leaders, politicians, librarians, students and faculty of higher education, researchers, and academicians.

Carbon Fiber, Second Edition, brings together available information on the production, properties, application and future of carbon fibers. This book will be of interest to those involved in the investigation of carbon fiber, carbon fiber manufacturing, and users. In addition, the recycling of carbon fiber reinforced polymers and the manufacturing of composites from recycled carbon fiber reinforced polymers are discussed. The book offers in-depth coverage on the production of carbon fiber and the global carbon fiber market, demand and major growth drivers. Carbon structures from biowaste, waste lignin and novel processes to obtain high purity lignin are presented, along with future directions.

Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications.

Biomass, Biofuels, Biochemical: Circular Bioeconomy: Current Developments and Future Outlook presents the views of experienced academicians and researchers working in the area of the circular bioeconomy. This book presents an assortment of Resource recovery, Waste Biorefineries, Bio-electrochemical systems, Biopolymers and Green solvents, Bio-adsorbents, and Technology transfer topics. Environmental engineers, biotechnologists, science graduates, chemical engineers, industrial experts and policymakers working in these areas will find the information on the circular economy and its important part in developing low carbon and resource-productive economies very informative. Methodologies and beneficial strategic approaches to address the usage of wastes from agriculture, co-products, and by-products are also discussed.

The Era of Artificial Intelligence, Machine Learning and Data Science in the Pharmaceutical Industry examines the drug discovery process, assessing how new technologies have improved effectiveness. Artificial intelligence and machine learning are considered the future for a wide range of disciplines and industries, including the pharmaceutical industry. In an environment where producing a single approved drug costs millions and takes many years of rigorous testing prior to its approval, reducing costs and time is of high interest. This book follows the journey that a drug company takes when producing a therapeutic, from the very beginning to ultimately benefitting a patient's life. This comprehensive resource will be useful to those working in the pharmaceutical industry, but will also be of interest to anyone doing research in chemical biology, computational chemistry, medicinal chemistry and bioinformatics.

NANOTECHNOLOGY IN MEDICINE Discover thorough insights into the toxicology of nanomaterials used in medicine In Nanotechnology in Medicine: Toxicity and Safety, an expert team of nanotechnologists delivers a robust and up-to-date review of current and future applications of nanotechnology in medicine with a special focus on neurodegenerative diseases, cancer, diagnostics, nano-nutraceuticals, dermatology, and gene therapy. The editors offer resources that address nanomaterial safety, which tends to be the greatest hurdle to obtaining the benefits of nanomedicine in healthcare. The book is a one-stop resource for recent and comprehensive information on the toxico logical and safety aspects of nanotechnology used in human health and medicine. It provides readers with cutting-edge techniques for delivering therapeutic agents into targeted cellular compartments, cells, tissues, and organs by using nanoparticulate carriers. The book also offers methodological considerations for toxicity, safety, and risk assessment. Nanotechnology in Medicine: Toxicity and Safety also provides readers with: A thorough introduction to the nanotoxicological aspects of nanomedicine, including translational nanomedicine and nanomedicine personalization Comprehensive introductions to nanoparticle toxicity and safety, including selenium nanoparticles and metallic nanoparticles Practical discussions of nanotoxicology and drug delivery, including gene delivery using nanocarriers and the use of nanomaterials for ocular delivery applications In-depth examinations of nanotechnology ethics and the regulatory framework of nanotechnology and medicine Perfect for researchers, post-doctoral candidates, and specialists in the fields of nanotechnology, nanomaterials, and nanocarriers, Nanotechnology in Medicine: Toxicity and Safety will also prove to be an indispensable part of the libraries of nanoengineering, nanomedicine, and biopharmaceutical professionals and nanobiotechnologists.

Current Developments in Biotechnology and Bioengineering: Sustainable Food Waste Management: Resource Recovery and Treatment covers the latest methods of food waste management and resource recovery from a sustainability perspective and is suitable for universities, municipalities, and companies working in the field. This book provides a comprehensive account of food waste chemistry, the latest techniques for food waste treatment and recycling, sustainability assessment (social, economic, environmental), and challenges in food waste management. The book explores recycling to value-added products using sustainable concepts and methodologies, and is useful as a course or reference book for biochemical engineering, environmental sustainability, and waste management.

Cell Instructive Materials to Control and Guide Cell Function: Programmable Bioactive Interfaces looks at the key determinants of the dynamic interface between cell and materials and how this can be applied in developing new, bioactive biomaterials surfaces. The interface between cell and synthetic materials has attracted considerable scientific and technological interest, leading to the awareness that functional interfaces can actively guide and control specific adhesion and recognitions events.

Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering.

Osseoconductive Surface Engineering for Orthopedic Implants provides a comprehensive overview of the state of the art of osseointegration based on surface-mediated engineering. It offers a practical approach to the design and development of implant surface engineering, by reviewing and discussing the usability and efficacy of each processing technique. The reader can learn about the variety, characteristics, advantages, challenges, and optimum parameters for each process-enabling targeted selection of coatings and technologies to enhance long-term implant-bone integration.

Modeling, Optimization and Control of Zinc Hydrometallurgical Purification Process provides a clear picture on how to develop a mathematical model for complex industrial processes, how to design the optimization strategy, and how to apply control methods in order to achieve desired production target. This book shares the authors' recent ideas/methodologies/algorithms on the intelligent manufacturing of complex industry processes, e.g., how to develop a descriptive framework which could enable the digitalization and visualization of a process and how to develop the controller when the process model is not available.

Computational Intelligence and Its Applications in Healthcare presents rapidly growing applications of computational intelligence for healthcare systems, including intelligent synthetic characters, man-machine interface, menu generators, user acceptance analysis, pictures archiving, and communication systems. Computational intelligence is the study of the design of intelligent agents, which are systems that act intelligently: they do what they think are appropriate for their circumstances and goals; they're flexible to changing environments and goals; they learn from experience; and they make appropriate choices given perceptual limitations and finite computation. Computational intelligence paradigms offer many advantages in maintaining and enhancing the field of healthcare.

Chemical and Process Plant Commissioning Handbook: A Practical Guide to Plant System and Equipment Installation and Commissioning, Second Edition, winner of the 2012 Basil Brennan Medal from the Institution of Chemical Engineers, is a guide to converting a newly constructed plant or equipment into a fully integrated and operational process unit. The book is supported by detailed, proven and effective commission templates and includes extensive commissioning scenarios that enable the reader to good commissioning practices. Sections focus on the critical safety assessment and inspection regimes necessary to ensure that new plants are compliant with OSHA and environmental requirements. Martin Killcross has comprehensively brought together the theory of textbooks and technical information obtained from sales literature to provide engineers with what they need to know before initiating talks with vendors regarding equipment selection.

Millets and Pseudo Cereals is the first comprehensive resource to focus on the potential crop improvements through genetic enhancements. The choice of food crop for a region is primarily determined by the conditions of climate and soil. Once labelled as orphan crops, millets and pseudo-cereals are now known as miracle grains due to their adaptation to harsh conditions and high nutritional quality. Small millets and pseudo-cereals are now seen to occupy special niches through their ability to adapt to challenging conditions. These crops have a comparative advantage in marginal lands where they withstand stress conditions and contribute to sustainable production. They also contribute to the diversity-richness and production stability of agro-ecosystems. Millets include sorghum, pearl millet, finger millet, foxtail millet, proso millet, barnyard millet, little millet and kodo millet while the other group which are not cereals but consumed as cereals and generally referred as pseudo-cereals comprises of grain amaranths, buckwheat and chenopods. Millets and Pseudo Cereals presents current information on the genetic architecture of important economic traits and the genomic resources for gene enabled breeding. This compilation contains information on the global status, available germplasm resources, nutritional value, breeding advancements, genomics applications and sustainability of agriculture through millets and pseudo-cereals cultivation. This book is a valuable resource for those conducting research and exploring new areas for advancing crop genetic understanding.

New and Future Developments in Microbial Biotechnology and Bioengineering presents an account of recent developments and applied aspects of fungi and its metabolites for human welfare. The fungi and its metabolites are employed in diverse fields of agri-food, biochemistry, chemical engineering, diagnostics, pharmaceuticals and medical device development. The book contains chapters by the eminent researchers working with fungi and fungal metabolites who explain their importance and potential in manifold prospects. The book includes a description of various fungal metabolites and their chemistry and biotechnology.

Improving Cereal Productivity through Climate Smart Practices is based on the presentations of the 4th International Group Meeting on "Wheat productivity enhancement through climate smart practices," and moves beyond the presentations to provide additional depth and breadth on this important topic. Focused specifically on wheat, and with chapters contributed by globally renowned pioneers in the field of cereal science, the book helps readers understand climate change and its effects on different aspects of wheat production in different parts of the world. This book will be important for those in research and industry seeking to contribute to the effective feeding of the world's population.

Microbial Biotechnology in Food and Health Science, volume one in the Applied Biotechnology Reviews series, offers two unique sections within the theme of genomics and bioprocessing and the bioengineering of microorganisms in the role of food science and human health. This volume provides review articles as the basis supporting biotechnological research useful to a wide scope of research initiatives. Important relevant information on genomics, proteomics and metabolomics are included as well as the emerging interdisciplinary area of synthetic biology which enables the metabolic engineering of microorganisms to produce pharmaceuticals. Applied Biotechnology Reviews is a series aimed at bringing all aspects of biotechnology as it is applied to food science - from agriculture through product processing into focus through topical volumes. Each volume will cover a relevant application approach in industrial biotechnology.

In the age of data science, the rapidly increasing amount of data is a major concern in numerous applications of computing operations and data storage. Duplicated data or redundant data is a main challenge in the field of data science research. Data Deduplication Approaches: Concepts, Strategies, and Challenges shows readers the various methods that can be used to eliminate multiple copies of the same files as well as duplicated segments or chunks of data within the associated files. Due to ever-increasing data duplication, its deduplication has become an especially useful field of research for storage environments, in particular persistent data storage. Data Deduplication Approaches provides readers with an overview of the concepts and background of data deduplication approaches, then proceeds to demonstrate in technical detail the strategies and challenges of real-time implementations of handling big data, data science, data backup, and recovery. The book also includes future research directions, case studies, and real-world applications of data deduplication, focusing on reduced storage, backup, recovery, and reliability.