La consapevolezza che l atopia sia l espressione di una piu facile suscettibilita della cute e delle mucose (oculari, respiratorie, digestive) agli agenti esterni in senso lato, porta alla logica conseguenza che i professionisti della salute che se ne debbano occupare siano vari e necessariamente coordinati. La nozione di atopia allarga il concetto tradizionale di allergia, perche in molti pazienti atopici non sono dimostrabili le classiche alterazioni immunologiche dell allergia. Questi due fatti hanno quindi portato alla creazione di Dipartimenti dell Atopia nelle strutture sanitarie di vari paesi.

Lo scopo di questa pubblicazione e quello di "tradurre" e schematizzare gli argomenti svolti in maniera accademica nella prima edizione della Scuola dell Atopia e che si sono condensati nel libro omonimo. Questo libro, invece, si propone di essere uno strumento sintetico e di rapida consultazione, destinato a chi si trovi di fronte a questi pazienti nel quotidiano, sia essi un medico o un pediatra di base ma anche un infermiere o un farmacista.

Il libro comprende un atlante fotografico cronologico ed annotato delle principali manifestazioni dell atopia cui segue la sezione degli algoritmi commentati su ciascuno dei principali capitoli. La terza parte, infine, offre un elenco critico dei "prodotti" per l atopia disponibili in Italia ed include, oltre ai farmaci topici, una selezione dei dermocosmetici utili nella gestione dei questi pazienti."

Organ transplantation has been successfully performed over the last 35 years and the number of organ allograft recipients is steadily increasing. Long-term immunosuppression, necessary for good graft function, inevitably induces undesired effects (particularly infectious and neoplastic ones) among which cutaneous ones are very frequent and potentially life-threatening. This book deals with all aspects of cutaneous disorders that may be encountered in the setting of organ transplantation. It reflects the pioneering work performed since long by Dermatologists in Lyon, in collaboration with teams specialised in kidney, heart, lung, liver and pancreas transplantation.

Melanocytic neoplasms are of capital importance for all surgical pathologists and dermatopathologists. These tumors span a huge range of morphologic expression and biologic behavior, are potentially of the highest medical significance and are often fraught with diagnostic pitfalls and high litigation risk.

"Pathology of Challenging Melanocytic Neoplasms "offers a dynamic text where readers will encounter a broad spectrum of challenging melanocytic lesions, both benign and malignant and will thereby acquire a solid, working knowledge that they can immediately apply to daily diagnosis. The authors aim to clarify this often thorny field, keeping a steady focus on patient-related issues. The volume emphasizes the practical application of basic morphologic principles, immunohistochemistry and molecular methods in order to secure a confident diagnosis. Abundant illustrations display the characteristic features of the most important disease entities.

Rather than being yet another encyclopedic work of reference, this volume takes a fresh approach as it resembles a series of stimulating seminars employing exemplary case material to highlight, illustrate, and succinctly discuss the key points. To this end, the reader will be guided through a series of paired cases that pose a significant diagnostic challenge. By comprehensively comparing and contrasting two related entities, each such chapter will illuminate an intellectual pathway through which an important diagnostic puzzle can be solved. To broaden the differential diagnosis even further, additional illustrative cases are added to each discussion. Algorithms and tables summarize key points. Clinically relevant, up-to-date references will be provided to guide further study. Written by experts in the field, this novel text will be of great value to surgical pathologists in practice and dermatologists as well as residents and fellows training in these specialties.

Dieses Praxisbuch ermoglicht den Einstieg in die Technik der Photoepilation. Nach der Erlauterung der notwendigen Grundlagen der Indikationsstellung und Therapievoraussetzungen werden die verschiedenen Lasersysteme in ihren Anwendungsgebieten erlautert. Zusatzlich sind auch praxisnahe Tipps zur Organisation, dem Investitionsaufwand, Hinweise zu Therapievereinbarungen mit den Patienten und Antworten auf mogliche rechtliche Fragen enthalten.

Fur alle, die in ihrer Praxis dieses Verfahren zur Haarentfernung anbieten.

Das Buch zum Kurs -aus der Praxis - fur die Praxis-."

L'esigenza di chiarire i concetti attuali dell'atopia, che per troppo tempo hanno oscillato tra una primitiva visione squisitamente clinica ed una successiva unicamente immunologica, era matura da tempo. L'avere compreso che il ruolo delle immunoglobuline E non e esaustivo ed avere accettato la salomonica divisione tra atopia intrinseca ed estrinseca, sono stati i primi due passi fondamentali. Le recenti scoperte del ruolo dell'immunita innata, e quindi dei peptidi antimicrobici, hanno aperto dei fondamentali spazi di comprensione nell'atopia e non solo. Quello che ora appare chiaro e che l'atopia non e la malattia di un organo ma piuttosto un difetto delle membrane che delimitano il nostro "self." Il fatto che queste membrane si chiamino pelle, intestino, congiuntiva, bronchi o quant'altro ha artificialmente frammentato la comprensione ed il trattamento di un fenomeno unitario. Questo libro vuole cercare di fare una sintesi delle diverse esperienze ma soprattutto essere uno stimolo a far si che la medicina si focalizzi costruttivamente sullo stesso bersaglio. Se cosi sara, non assisteremo piu a"guerre di religione" tra scienziati e medici pratici o, peggio ancora, tra i differenti specialisti che si contendono il paziente. Se l'atopia, come noi crediamo, e un problema globale, esso puo essere adeguatamente affrontato solo in un contesto pluridisciplinare e in clima collaborativo, non solo tra medico e medico ma anche tra medico e paziente.

Reflectance confocal microscopy enables lesions in skin to be examined without excision, but with improved diagnostic accuracy, assessment of dermoscopic-histologic correlation, assessment of surgical margins, as well as speed and convenience for the physician and patient. This extensively enlarged and updated text reviews the current and future state of the art for those involved with the diagnosis and treatment of skin tumors, with a greatly increased amount of material on the expected normal patterns of skin throughout life and on non-melanocytic tumors.

This second edition of the Oxford Handbook of Medical Dermatology provides practical and accessible advice on how to reach a diagnosis or create a management plan when faced with patients with a range of skin conditions. Giving concise and clear guidance on investigation and treatment, this Handbook helps doctors adopt a step-by-step approach at the bedside to make sense of skin problems by analysing clinical signs. Illustrated and in full colour, it covers skin physiology, an overview of common skin conditions, and skin problems commonly seen in a broad range of specialities, from rheumatology to psychiatry, as well as children and the elderly. Now comprehensively updated with new clinical pictures, references, and extensively reworked chapters on skin in infancy and childhood, cutaneous reactions to drugs, skin tumours, and rheumatology. This second edition now includes a brand new chapter on skin and genetics, detailing this fast-growing and important area of dermatology, promoting good communication with a patient-centred and practical common-sense approach for trainees in dermatology, junior doctors, GPs, and medical students.

A unique compilation of expertise on anatomy, physiology, clinical issues, and current research, this textbook analyzes the range of presentation with age, ethnicity, symptoms, disorders, diagnoses, and toxicity. The second edition of this essential resource for anyone taking care of female patients has been doubled in scope to include additional chapters. All physicians, whether dermatologists or gynaecologists, as well as those researching the scientific evidence and symptoms, will benefit from the experience of the expert contributors and editors gathered here.

Since the first edition of this book was published in 2004, to much acclaim, the pace of innovation in the field of skin metrology has increased and various new technologies have become available. This new, revised edition reflects these advances by presenting the current theory and practice of noninvasive investigation and measurement of the skin and its appendices in health and disease. The first, extensive part of this authoritative work is devoted to the physiology and metrology of the various structural components of the skin. Skin functions and their measurement are then discussed in detail, with sections on mechanical protection, photoprotection, barrier function, immune function, thermoregulation, and sensory function. In addition, careful consideration is given to skin disease rating and skin maps, and a unique list of physical and biological constants and units is provided. Not only is this new edition the first comprehensive, practical handbook in this domain - it will also serve as a manual of skin physiology and collates anatomical, functional, and physical quantitative data that would otherwise be arduous to retrieve because of their dispersal throughout the literature. It will prove a valuable resource for dermatologists, cosmetologists, bioengineers, physiologists, pharmacists, and all others who deal with the skin in their work.

Aktinische Keratosen gehoren zu den haufigsten Malignomen des Menschen. Durch die Zunahme der Lebenserwartung wird ihre Inzidenz in den nachsten Jahren weiter steigen. Mikroskopisch und tumorbiologisch handelt es sich bei aktinischen Keratosen um Carcinomata in situ, deren Dynamik einer Summe von individuellen Uberwachungsfaktoren unterliegt (tumor surveillance).

Die vorliegende Arbeit erortert die Historie, Klinik, Histologie und Pathophysiologie dieser epithelialen Neoplasien und stellt neueste therapeutische Strategien vor.

Patienten und ihre behandelnden Arzte werden zunehmend zu Partnern im diagnostischen und therapeutischen Prozess. Bei vielen allergischen Erkrankungen hangt der Therapieerfolg direkt von der Mitarbeit des informierten Patienten ab. Vorliegendes Buch + CD-ROM stellt effiziente Hilfsmittel fur die Allergie-Patienteninformation bereit. Wahrend der umfangreiche lexikalische Teil (mit vielen auf der CD anklickbaren Verweisen) die Praxishelfer fundiert uber allergologische Sachverhalte informiert, bietet eine Bibliothek von Informationsblattern Tipps und Informationen fur jede relevante allergische Indikation. Sie konnen zum Mitgeben fur die Patienten von der CD nach Bedarf ausgedruckt werden. Eine umfassende Bibliographie sowie eine gut strukturierte Linkliste, jeweils differenziert nach Informationsbedurfnis von Arzt bzw. Patient helfen, den Rahmen des Buchs sprengende Fragen zu beantworten. Der so verbesserte Wissenstransfer entlastet das arztliche Zeitbudget nachhaltig.

Dieser kompetente Praxisleitfaden enthalt alles, was man uber die Arzneimitteltherapie von Venenerkrankungen wissen muss. Dabei wird nicht nur auf die Wirkstoffe, sondern auch auf die Grundlagen eingegangen. Anerkannte Indikationen werden ebenso dargestellt wie die unerwunschten Wirkungen. Nutzen-Risiko-Relation und Aufwand-Nutzen-Relation sind die zentralen Parameter fur die Arzneimittelauswahl. Hinweise fur die Betreuung von Patienten und Patiententipps runden das Werk ab.

Textbook of Psoriasis is a comprehensive and highly illustrated guide to this dermatological disorder. This book is divided into twelve chapters, covering all aspects of psoriasis, from clinical, pathological and therapeutic, to the psychological impact of the condition. A general introduction is followed by chapters on epidemiology, aetiopathogenesis, paediatric psoriasis, pregnancy, HIV, and systemic disease. Later chapters include information on treatment and potential complications. Textbook of Psoriasis is enhanced by over 300 full colour images and illustrations. The inclusion of several recent dermatology research studies pertaining to psoriasis make this book and authoritative and up to date resource for dermatologists. Key Points Comprehensive and highly illustrated guide to psoriasis Updated with new research study findings 302 full colour images and illustrations

This volume outlines and examines current understanding of botulinum toxin and its various therapeutic applications. It presents therapeutic uses across a variety of medical subspecialties and patient populations. Each chapter focuses on a particular symptom and explains how botulinum toxin is currently used for treatment. Coverage also examines questions of immunity and explores economic issues. Written by leaders in their fields respected for their progressive approach to treatment, the book encourages responsible research into new and novel uses of botulinum toxin.

The book will educate and decode the role of vitamins, essential fatty acids and other nutraceuticals on skin health and their tremendous impact to the current needs of the skin care industry. Focus on conditions, as acne, dermatitis, dry scaly skin or alopecia will provide a comprehensive knowledge of the relationship of nutrition and skin as well as the current attempts in nutritional or dermatological research. It will stimulate food professionals to brainstorm for new products and opportunities that will target the emerging antiaging and wellness trends and modern consumer needs.

Im Rahmen der Veranderungen innerhalb des Gesundheitswesens gewinnt die Laserbehandlung z. B. auch fur ambulante Eingriffe zunehmend an Bedeutung. Diese praxisorientierte, kompakte Darstellung der gegenwartig zur Verfugung stehenden Laserbehandlungsmassnahmen im Kopf-Hals-Bereich kommt dem Bedarf nach einheitlichen Empfehlungen zum Einsatz bestimmter Lasertypen fur spezifische Regionen nach. Fur die einzelnen Subgebiete der Kopf-Hals-Region wurden Spezialisten nicht nur aus der HNO-Heilkunde sondern auch aus benachbarten Disziplinen herangezogen."

Die Diagnose und Therapie sexuell ubertragbarer Erkrankungen bestimmen zunehmend den Alltag der arztlichen Praxis. Ferntourismus und die Reisewut der Patienten sorgen fur neuartige Krankheiten, die erst einmal erkannt werden mussen. Zudem muss sich der Arzt mit unterschiedlichen Therapieschemata auseinandersetzen. Gibt es Leitlinien zu diesem wichtigen Thema? Ja, bei Springer: Die Leitlinien 2001 der deutschen STD-Gesellschaft klaren kompakt und ubersichtlich uber jedes einzelne Krankheitsbild auf und erlautern Dosierungsvorschlage sowie individuelle therapeutische Massnahmen. In erganzenden Kapiteln werden die Grundzuge der Epidemiologie, der Pravention und der gesetzlichen Grundlagen dargestellt.

Dieser kompetente Praxisleitfaden enthalt alles, was man uber die Arzneimitteltherapie von Dermatomykosen wissen muss. Dabei wird nicht nur auf die Wirkstoffe, sondern auch auf die Grundlagen eingegangen. Anerkannte Indikationen werden ebenso dargestellt wie die unerwunschten Wirkungen. Nutzen-Risiko-Relation und Aufwand-Nutzen-Relation sind die zentralen Parameter fur die Arzneimittelauswahl. Hinweise fur die Betreuung von Patienten und Patiententips runden das Werk ab."

Die Photobiologie untersucht die komplexen Auswirkungen der Sonnenstrah lung auf biologische Systeme. Der Haut kommt in diesem Kontext als Grenz organ zu unserer Umwelt eine ganz besondere Rolle zu. So hat das Teilgebiet der Photodermatologie einerseits als Grundlagenwissenschaft, andererseits als klinische Spezialitat in den letzten Jahren enorm an Bedeutung gewonnen. Durch die Ermittlung von selektiven therapeutischen Aktionsspektren lassen sich heute mit geeigneten Strahlenquellen eine Reihe von Hauterkrankungen sehr gezielt und effektiv therapieren und unter Kontrolle halten. Anderseits vermag die Sonnenstrahlung eine grosse Anzahl von Dermatosen zu induzie ren - die Photodermatosen. Photodermatosen werden haufig diagnostiziert. Skandinavische und amerikanische Untersuchungen konnten zeigen, dass z. B. die polymorphe Lichtdermatose bei ca. 15% der jungeren weissen Bevolke rung vorkommt. Da Patienten mit Photodermatosen sich haufig im erschei nungsfreien Intervall vorstellen und spezifische laborchemische Parameter bei den meisten Photodermatosen nicht zu erheben sind, kommt den Photopro vokationstestungen eine besondere Bedeutung zu. 1983 wurde an der Hautklinik der Heinrich-Heine-Universitat Dusseldorf ein Labor fur photodiagnostische Testverfahren eingerichtet, in dem in der Folgezeit alle Patienten mit Verdacht auf eine Photodermatose getestet wur den. Ziel dieser Testverfahren ist es, die Diagnose mittels Reproduktion in einem Testareal auf der Haut zu sichern und die auslosenden Strahlen, das sog. Aktionsspektrum, zu ermitteln. Fur jede Photodermatose musste dafur ein spezifisches Provokationsprotokoll aufgrund von Literaturangaben und Voruntersuchungen entwickelt werden, da akzeptierte Regeln hierfur nicht existieren."

Die klassische Magistralrezeptur hat eine lange Tradition und stutzt sich vorwiegend auf Empirie. In der Praxis sind nahezu 50% der durch Dermatologen verordneten Externa Magistralrezepturen. Es ist unumganglich, dass die Magistralrezeptur dem gegenwartigen Stand des wissenschaftlichen Fortschrittes angepasst wird. Obsolete Wirkstoffe mussen vermieden werden. Die Galenik soll optimalisiert werden. Ahnlich wie bei Spezialitaten soll sich der verordnende Arzt darauf verlassen konnen, dass bei empfohlenen Magistralrezepturen die pharmakologische Wirkung des Wirkstoffes in der Grundlage gesichert oder zumindest sehr wahrscheinlich ist. Externagrundlagen fur bestimmte Indikationen sollen gezielt unter wissenschaftlichen Gesichtspunkten zusammengestellt werden. Hauptanliegen des Buches sind gezielte therapeutische Empfehlungen unter diesen Gesichtspunkten."

Challenging Cases in Allergic and Immunologic Diseases of the Skin offers clinicians a wide range of challenging cases that are certain to provide hours of thoughtful and instructive review. Using a case study format and including excellent quality color images, Challenging Cases in Allergic and Immunologic Diseases of the Skin consists of five parts and 20 chapters. The chapters cover such areas as allergic rhinitis, allergic diseases of the eye, drug-induced urticaria, cosmetic allergy, drug allergy, latex allergy, atopic dermatitis, vasculitis, and a range of other commonly seen disorders of the skin. Each chapter comprises at least two cases that are followed by a differential diagnosis, discussion, and five multiple choice questions for thoughtful stimulation and excellent value as a teaching tool. Comprehensive, concise, and well-designed in presentation, Challenging Cases in Allergic and Immunologic Diseases of the Skin is a one-of-a-kind resource that will become a standard resource for all clinicians who care for patients with allergic and immunologic diseases of the skin.