Post-burn scar contractures are a commonly encountered problem in the field of plastic and reconstructive surgery. Nevertheless, many physicians still lack adequate knowledge on beneficial treatments. In this up-to-date atlas, leading specialists in post-burn treatment and the reconstruction of post-burn scar contractures depict in detail not only surgical techniques but also a variety of advantageous wound treatments. Many new methods invented by the authors are presented. Operative techniques are depicted in detail, and clear guidance is provided on selection of the most appropriate flap surgery. Advice is also given on how to prevent permanently disabling restriction of joint movement as a result of contractures and how to achieve good aesthetic reconstruction. This atlas is designed to appeal to a wide audience, from beginners to specialists. It will prove invaluable for doctors of every kind who deal with wound management.

The decade that has passed since publication of the second edition of this textbook has not only witnessed a tremendous increase in knowledge within the ? eld of and- logy, but also seen the ? eld itself achieve a newfound status within the medical p- fession. Knowledge and status have been of mutual bene? t to the ? eld and the growing critical mass of diagnostic and therapeutic possibilities have caused andrology to be recognized as a medical subspecialty in some countries such as Germany, Poland, and Estonia. The European Academy of Andrology (EAA) served as a pacemaker for this development and continues to strive for establishment of andrology as a clinical ? eld. Well-designed curricula and qualifying examinations have contributed to the of? cial recognition of andrology as a speciality. This recognition of the ? eld helps patients with andrological problems to ? nd the specialist they seek. This textbook summarizes the current state of knowledge in the ? eld of andrology. It is a source of knowledge to all those who are or want to become andrologists. In addition, as andrology is clearly an interdisciplinary ? eld, this book may serve as a compendium and source of reference for all those physicians and biologists active in neighboring areas, who want to obtain an overview of andrology and who require information on special problems. The extensive references are timely and up to date.

This comprehensive guide covers all aspects of mastopexy and breast reduction, ranging from anatomy to the variety of procedures in mastopexy, mastopexy/breast reduction, and breast reduction, preoperative care, complications, breast tumors (benign and malignant), and medicolegal aspects.

The demand for cosmetic procedures is increasing worldwide. This book presents all the potential side-effects and complications of the most frequently used procedures in aesthetic dermatology and provides sound practical advice on their management. It will be helpful not only to beginners but also to experienced dermatologists who want to start performing new procedures. The text is fully illustrated and very simple to consult. For each procedure, the book discusses both common and uncommon side-effects and complications, provides tips on how to avoid them, and explains clearly how they are best treated.

Autoimmune disorders of the skin remain an enigma for many clinicians and scientists not familiar with these mostly severe and chronic diseases. The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The third edition has been thoroughly updated and extended by chapters on paraneoplastic cutaneous syndromes, atopic dermatitis and autoimmunity and Skin manifestations of rheumatic diseases.

This volume compiles the perspectives of a multi-author team examining the entire spectrum of burn reconstruction and long-term treatment. Individual chapters cover basic aspects of wound healing and scarring, and those of plastic surgery relating to tissue rearrangement and the use of flaps, as well as the long-term use of skin and skin substitutes. Furthermore, topics such as rehabilitation and scar management are addressed in detail. This part provides detailed reconstruction guidelines divided by anatomic region (e.g. face, hands,...), as well as aspects of future trends and prospects in burn reconstruction, among which are e.g. allotransplantation and bionics.

Of all the techniques used to treat non melanoma skin cancer, the highest cure rates belong to the Mohs surgical procedure. Critical to this technique is optimal preparation and interpretation of frozen sections. With more than 400 high resolution figures, the Atlas of Mohs and Frozen Section Cutaneous Pathology is the premier textbook on the topic, serving as a highly practical guide to microscopic analysis, diagnosis, and discrimination of common and problematic cutaneous neoplasms. Highlights of the Atlas include diagnosis of basic and routine dermatologic entities, diagnosis and distinction of rare and/or deadly neoplasms such as dermatofibrosarcoma protuberans and merkel cell carcinoma, a troubleshooting guide dealing with quality control of the frozen section technique, and discussion of new techniques including immunohistochemistry. Comprehensive and presented in full color, the Atlas of Mohs and Frozen Section Cutaneous Pathology is an indispensable reference for anyone involved with the Mohs procedure, including dermatologic surgeons, Mohs cutaneous surgeons, as well as pathologists and dermatopathologists who perform frozen section analysis of cutaneous specimens.

Over the decades, research has demonstrated that in categories of life deemed to be important, beautiful people achieve more desirable outcomes, are judged more favorably, and receive preferential treatment. An understanding of the historical aspects, science, and implications of what the human mind finds aesthetically pleasing is quintessential for dermatologists, plastic surgeons, and others who practice aesthetic medicine as the importance of beauty in today's society is what brings patients into clinics. While an element of dissatisfaction with one's appearance is commonplace, clinicians should remain vigilant for individuals who seek cosmetic procedures to quell excessive body image concerns that are out of proportion to objective physical findings. Body dysmorphic disorder (BDD) is a disorder of self-perception; it is the impairing preoccupation with a nonexistent or minimal flaw in appearance. According to recent statistics, BDD occurs in 0.7-2.4% of the general population; however, multiple studies have suggested an incidence of 6-16% in patients seeking aesthetic medical treatments. Moreover, a vast majority will at some point seek dermatologic treatment and cosmetic surgery. Such patients are unlikely to be satisfied with corrective procedures, and only 15% of dermatologists surveyed thought that they could successfully treat BDD. Therefore, Beauty and Body Dysmor phic Disorder aims to assist dermatologists, plastic surgeons, and other aesthetic providers in recognizing key characteristics as well as providing treatment strategies to help in caring for those with BDD.

Written by a leading dermatologist, The Blue Man and Other Stories of the Skin provides a compelling and accessible introduction to the life of our largest organ, while also recounting the author's experiences with memorable patients he has treated who suffer from mysterious skin conditions. Robert Norman begins by highlighting the qualities of the skin, tracing the history of its conditions and diseases, then examining the cultural, social and psychological impact of both color and irregularity. The book also features an absorbing collection of stories about some of his most intriguing patients: from a man whose skin mysteriously turned blue, to a hypochondriacal woman who begins to show signs of a life-threatening disease. This is a fascinating account of the dynamic nature of the skin, and the people who inhabit it.

Histamine is an important mediator of allergic diseases, but knowledge of histamine as a cause of numerous non-allergic symptoms and signs is limited. This book offers wide-ranging coverage of histamine intolerance. There is extensive background discussion of the origin of histamine, its content in food and alcoholic beverages and intolerance to red wine. Diagnosis of histamine intolerance is explained and the various symptoms of histamine intolerance are clearly described. Subsequent chapters cover the relation of histamine to a wide variety of conditions, including drug intolerance, atopic dermatitis, seasickness and osteoporosis. This book will prove of value in clinical practice by facilitating differential diagnosis, which is by no means straightforward given the multiplicity of symptoms of histamine intolerance and by assisting in the selection of therapeutic measures.

As a result to the recent significant developments, both in the field of cutaneous pathology and clinical dermatology, many cutaneous neural tumors are now being diagnosed by specialists like dermatopathologists, and treated by dermatologists or dermatologic surgeons. Cutaneous Neural Neoplasms: A Practical Guide provides an essential aid in diagnosis by discussing the cardinal clinico-pathologic features of cutaneous tumors relevant to these specialists. It covers detailed pathologic features, and their differential diagnosis. Applicable special diagnostic techniques are extensively illustrated. Whenever relevant, key therapeutic recommendations are provided. The authors approach each entity by presenting clinical and/or gross photographs when relevant with discussion of the clinical features, followed by the tabulated list of key pathologic features with corresponding histopathologic illustrations. Therapeutic recommendations are summarized. Cutaneous Neural Neoplasms: A Practical Guide is an important new volume that fills a major gap in the currently available resources for practicing physicians, and provides them with an appropriate knowledge base to handle these challenging tumors in the most up-to-date fashion.

Mohs surgery is microscopically controlled surgery used to treat common types of skin cancer and allows for the removal of a skin cancer with a very narrow surgical margin and a high cure rate. However, for those involved with the Mohs procedure, it is critical to understand the optimal preparation and interpretation of frozen sections. Complete with hundreds of high resolution figures, Atlas of Practical Mohs Histopathology is written by leading experts in the field and discusses everything from normal skin histology and rare tumors to pitfalls and incidental findings. Dermatologic surgeons, Mohs cutaneous surgeons, dermatopathologists and pathologists alike will find this book to be a comprehensive and indispensable reference.

This is the first and only book on the diagnosis and treatment of cicatricial alopecia, written by leading experts in the field. This highly illustrated and practical text helps residents and practicing dermatologists to accurately diagnose and treat the scarring alopecias.

This book focuses on the use and significance of in vivo reflectance confocal microscopy (RCM) for non-invasive high-resolution imaging of the skin. All of the chapters in this hands-on guide are generously illustrated with numerous confocal images and structured in a reader-friendly way. The contents include detailed information on the most relevant and up-to-date aspects of RCM, schematic drawings summarizing and explaining the most important RCM criteria, and a chapter specifically devoted to bridging the gap between dermoscopy, RCM, and histopathology. At the end of each chapter, core messages recapitulate the most pertinent aspects. Reflectance Confocal Microscopy for Skin Diseases will be a valuable resource for all physicians involved in the diagnosis and treatment of neoplastic and inflammatory skin diseases.

This volume covers the entire spectrum of acute burn treatment. Individual chapters deal with basic aspects of different burn mechanisms as well as the acute care of burn patients. Pre-hospital management, critical care and basic concepts of burn surgery related to the acute phase, as well as the use of skin and skin substitutes in early stages of therapy are addressed in this volume. Chapters on supportive therapies such as optimizing nutrition and fluid homeostasis, infection control and treatment, respiratory support and pain management complete the comprehensive approach to the patient in this early stage of treatment, while chapters on epidemiology, prevention and disaster management enable the reader to evaluate the given information in a broader context.

This reader-friendly and unique compendium on all aspects of non-invasive facial rejuvenation shows the current approach to the issue. It describes when and how to use laser and laser-like technology, the variety of superficial and deep peels which can be used by themselves or in conjunction with lasers. Last but not least, it also covers the variety of dermal fillers and skin volume enhancement agents and the increasing cosmetic uses of botulinum toxin. Novices as well as experts will benefit from the wealth of experience and expert practical information of the authors who are world-renowned experts in their field.

The majority of tropical diseases manifest themselves through the skin, and while many can be diagnosed on physical examination, dermatopathologic results are often of critical importance to the diagnostic process. However, general dermatopathology texts lack images of diseases endemic in the developing world; they also lack clinical correlates linking the pathology to the clinical entity. This is a problem, because greater movement between countries where tropical diseases are prevalent and Europe, North America and other developed nations makes it essential for physicians to be able to recognize, diagnose and treat these diseases. Dermatopathology of Tropical Diseases covers the pathology and clinical correlations of the most important tropical diseases. Each entity is described using brief text that summarises its epidemiology, pathogenesis and clinical features. The diagnostic process is then described and illustrated using both clinical and histopathologic images. Wherever possible, different examples are shown of the same disease, in order to illustrate as wide a variety of presentations as possible. Extensively illustrated with almost 600 photographs, Dermatopathology of Tropical Diseases is an invaluable resource for dermatopathologists, pathologists and dermatologists based in the developing world as well as those in developed countries who see tropical diseases in returned travellers and immigrant populations. Key features Includes chapters on all major tropical diseases, with both clinical and histopathological images provided for each entity, allowing the reader to correlate pathological characteristics with the clinical presentation of each disease Wherever possible, different examples of the same disease are shown, to illustrate the variety of presentations Lavishly illustrated with almost 600 colour photographs

This fully revised and updated second edition of Sexual Health and Genital Medicine in Clinical Practice covers the range of conditions seen in genitourinary medicine, sexual health and sexually transmitted infection clinics, making it a useful and practical guide to all health practitioners in this area. This book is aimed at medical practitioners who require a quick reference guide to help with diagnosis and management of genital problems. In addition, it provides essential guidance on what to do next when faced with a patient presenting with a genital complaint, whether the patient can be successfully treated with a drug regimen or needs to be referred up to the Sexual Health and Genital Medicine specialist. Sexual Health and Genital Medicine in Clinical Practice will be of particular interest to residents on their rotations through this field of medicine, doctors in training, specialist nurses, and primary care practitioners.

Melanoma is one of the most types of cancer. When melanoma is detected at an early stage, treatment is highly successful, but outcomes can be poor when the disease is advanced. There has been significant progress in our understanding of the molecular biology, genetics, and immunology of melanoma over the past decade. This has been accompanied by rapid advances in therapeutic strategies for patients with melanoma. This book provides the clinician and the researcher with a broad understanding of the molecular and cellular pathogenesis of melanoma, explores the clinical characteristics and criteria for clinical and pathological staging of the disease, and provides an overview of current and evolving treatment strategies in the adjuvant, metastatic, and preventive settings. The treatment of special populations and rare variants of melanoma that often present particular clinical challenges is also covered. Authored by international experts in melanoma biology and clinical management, this volume concisely explains how to diagnose, treat, and prevent melanoma while reviewing advances in basic science and providing an overview of innovative approaches still under development.

Human hair is the subject of a remarkably wide range of scientific investigations. Its chemical and physical properties are of importance to the cosmetics industry, forensic scientists and to biomedical researchers. The fifth edition of this book confirms its position as the definitive monograph on the subject. Previous editions were recognized as "concise and thorough" (Journal of the American Chemical Society), "an invaluable resource" (Canadian Forensic Science Society Journal), and "highly recommended" (Textile Research Journal). Chemical and Physical Behavior of Human Hair is a teaching guide and reference volume for cosmetic chemists and other scientists in the hair products industry, academic researchers studying hair and hair growth, textile scientists and forensic specialists. Features of the Fifth Edition: Recent advances in the classification and characterization of the different proteins and genes in IF and keratin associated proteins in human hair are described. The mechanism and incidence of hair growth and loss and hair density vs. age of males & females are described for Asians, Caucasians and Africans in different scalp regions. Details of hair surface lipids and cuticle membranes provide a better understanding of the surface and organization of the CMC and its involvement in stress strain is presented. Recent evidence demonstrates a more bilateral structure in curly hair and a more concentric arrangement of different cortical proteins in straighter hair. SNPs involved in hair form (curl and coarseness) and pigmentation and genes in alopecia and hair abnormalities are described. The latest biosynthetic scheme for hair pigments and structures for these and the different response of red versus brown-black pigments to photodegradation is described. A new method for curvature on 2,400 persons from different countries and groups is used to assign curvature throughout this book. Additional data for age and effects on diameter, ellipticity, elastic modulus, break stress and other parameters are presented with much larger data sets featuring statistical analyses. Hair conditioning, strength, breakage, split ends, flyaway, shine, combing ease, body, style retention, manageability and feel parameters are defined and described. A new section of different life stages by age groups considering collective and individual changes in hair fiber properties with age and how these affect assembly properties.

Inflammatory Dermatopathology: A Pathologist's Survival Guide provides expert guidance for the reader to develop a systematic approach to the diagnosis of inflammatory disorders of the skin. It covers the most common and clinically important inflammatory disorders of the skin through an image-rich easy to read format. Each section includes practical tips to help navigate the differential diagnosis. Microscopic features are listed as bullet points to enhance readability. Examples of diagnostic comments that practicing pathologists can utilize in their own reports are also provided. Demonstrating a global understanding of inflammatory dermatoses in a quick and efficient manner, Inflammatory Dermatopathology: A Pathologist's Survival Guide will both guide the reader in how to approach inflammatory dermatoses, as well as provide a tool that will help with the writing of surgical pathology reports.

This user-friendly reference tool presents clinical scenarios and discusses some practical complementary and alternative therapies available in dermatology. It focuses on peer-reviewed data that are suitable for use in a conventional dermatology practice and helps dermatologists guide their patients when faced with questions regarding integrative dermatology using an evidence-based, reader-friendly, and case-focused approach. Within the field of dermatology, there is a marked void in the understanding of complementary and alternative approaches, though dermatologists frequently use off-label therapies to manage chronic conditions. They do so, however, with a range of success and potentially considerable side effect profiles. Handbook of Integrative Dermatology is a must-have tool for any practicing dermatologist.

Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2-30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs.

This book is dedicated to our readers with the intention of providing an informative exposition of the myositis syndromes. It is also presented in the hope that perhaps it may serve to inspire and stimulate discussion and research into these disabling disorders. Included are descriptions of clinical features, differential diagnosis, pathogenetic mechanisms, and approaches to therapy. Current concepts of classi- cation and diagnostic techniques are also presented. The production staff at Humana Springer, especially Ms. F. Louie and Ms. C. Walsh, have been instrumental and invaluable in allowing this work to see the light of day. Above all, the scholarly essays of the contributing authors are acknowledged with gratitude. They have given this volume its character and existence. New York, NY Lawrence J. Kagen v Contents Preface ...v Contributors ...ix 1 Evaluation of the Patient ...1 Lawrence J. Kagen 2 Classification of Idiopathic Inflammatory Myopathies ...15 Frederick W. Miller 3 The Inflammatory Milieu: Cells and Cytokines...29 Ann M. Reed and Thomas A. Griffin 4 Juvenile Dermatomyositis: An Update on Clinical and Laboratory Findings ...55 Lauren M. Pachman 5 Inclusion Body Myositis ...87 Lawrence J. Kagen 6 The Role of Muscle Biopsy in the Diagnosis of Inflammatory Myopathy ...95 Sakir Humayun Gultekin 7 Electromyography ...1 1 1 Hans L. Carlson 8 Magnetic Resonance Imaging of Myopathies and Myositis ...127 Carolyn M. Sofka 9 Ultrasound in the Evaluation of the Inflammatory Myopathies ...147 Ronald S. Adler and Giovanna Garofalo vii viii Contents 10 Serological Findings ...165 Ira N.