THIS VOLUME, WHICH IS DESIGNED FOR STAND-ALONE USE IN TEACHING AND RESEARCH, FOCUSES ON QUANTUM CHEMISTRY, AN AREA OF SCIENCE THAT MANY CONSIDER TO BE THE CENTRAL CORE OF COMPUTATIONAL CHEMISTRY. TUTORIALS AND REVIEWS COVER

1. HOW TO OBTAIN SIMPLE CHEMICAL INSIGHT AND CONCEPTS FROM DENSITY FUNCTIONAL THEORY CALCULATIONS,
2. HOW TO MODEL PHOTOCHEMICAL REACTIONS AND EXCITED STATES, AND
3. HOW TO COMPUTE ENTHALPIES OF FORMATION OF MOLECULES.

A FOURTH CHAPTER TRACES CANADIAN RESEARCH IN THE EVOLUTION OF COMPUTATIONAL CHEMISTRY. ALSO INCLUDED WITH THIS VOLUME IS A SPECIAL TRIBUTE TO QCPE.FROM REVIEWS OF THE SERIES

"Reviews in Computational Chemistry proves itself an invaluable resource to the computational chemist. This series has a place in every computational chemist’s library."—Journal of the American Chemical Society

New trends in solid-phase extraction for analytical use—a practical introduction.

Owing to its low cost, ease of use, and nonpolluting means of preparing samples for analysis, solid-phase extraction (SPE) is fast overtaking traditional liquid—liquid methods in clinical, pharmaceutical, agricultural, and industrial applications. This book describes what analytical scientists and technicians need to know about this emerging procedure: how it works, how to choose from available techniques, how to utilize it effectively in the laboratory. Along with the historical perspective and fundamental principles, this practical book reviews the latest literature on solid-phase materials, equipment, and applications—including EPA-endorsed techniques. Special features include:

• Coverage of separation and uptake methods.
• Promising developments in the use of membrane disks.
• The advantages of using polymeric resins over silica materials.
• Mechanism and use of ion-exchange materials for SPE.
• A remarkably complete chapter on the extraction of metal ions.
• Groundbreaking research in the miniaturized SPE technique.

SOLID-PHASE MICROEXTRACTION Theory and Practice Janusz Pawliszyn 1997 (0-471-19034-9) 264 pp.

In Laser Physics the interaction of radiation and matter, and the principles of laser operation are treated at a level suitable for fourth-year undergraduate courses or introductory graduate courses in physics, chemistry or engineering. The factors which determine efficiency, wavelength coverage, output power, and beam quality of the different classes of laser are treated both in terms of fundamental theory and practical construction aspects. Details of established types of solid-state, semiconductor, and gas lasers are examined together with the techniques that enable their output to be converted widely across the spectrum. The latest advances in high power fibre lasers, femtosecond lasers, and X-ray lasers are explained. The text is liberally illustrated with more than 300 diagrams. An extensive bibliography is provided, together with numerical problems in each chapter. Solutions are available via the web.
To request a copy of the Solutions Manual, visit: http: //global.oup.com/uk/academic/physics/admin/solutions

A complete guide to choosing and using the best analytical technique for the job at hand

Today's new generation of spectroscopic instrumentation allows for more accurate and varied measurements than ever before. At the same time, increasingly powerful, user-friendly PC hardware and software make running those instruments relative child's play. However, although they may have solved many of the problems traditionally associated with conducting molecular spectroscopic analyses, these refinements tend to obscure inherent technical challenges which, if not taken into consideration, can seriously undermine a research initiative. Modern Techniques in Applied Molecular Spectroscopy gives scientists and technicians the knowledge they need to address those challenges and to make optimal selection and use of contemporary molecular spectroscopic techniques and technologies.

While editor Francis Mirabella and contributors provide ample background information about how and why individual techniques work, they concentrate on practical considerations of crucial concern to researchers working in industry. For each technique covered, they provide expert guidance on method selection, sample preparation, troubleshooting, data handling and analysis, and more. Adhering principally to mid-IR molecular spectroscopic techniques, they clearly describe the guiding principles behind, characteristics of, and suitable applications for transmission spectroscopy, reflectance spectroscopies, photoacoustic spectroscopy, infrared and Raman microspectroscopy, fiber optic techniques, and emission spectroscopy.

Modern Techniques in Applied Molecular Spectroscopy is an indispensable working resource for analytical scientists and technicians working in an array of industries.

At this very moment the most ambitious scientific experiment of all time is beginning, and yet its precise aims are little understood by the general public. This book aims to provide an everyman's guide for understanding and following the discoveries that will take place within the next few years at the Large Hadron Collider project at CERN. The reader is invited to share an insider's view of the theory of particle physics, and is equipped to appreciate the scale of the intellectual revolution that is about to take place. The technological innovations required to build the LHC are among the most astonishing aspects of this scientific adventure, and they too are described here as part of the LHC story. The book culminates with an outline of the scientific aims and expectations at the LHC. Does the mysterious Higgs boson exist? Does space hide supersymmetry or extend into extra dimensions? How can colliding protons at the LHC unlock the secrets of the origin of our universe? These questions are all framed and then addressed by an expert in the field. While making no compromises in accuracy, this highly technical material is presented in a friendly, accessible style. The book's aim is not just to inform, but to give the reader the physicist's sense of awe and excitement, as we stand on the brink of a new era in understanding the world in which we all live.

The measurement of metabolic rates is central to important questions in many areas of physiological research. Unfortunately these measurements are anything but straightforward, with numerous pitfalls awaiting both the novice and even the experienced investigator. The original edition of this work, published in 2008, quickly became the principle "how to" manual for the field. It successfully de-mystified the topic, explaining every common variation of metabolic rate measurement. Background information on different analyzer and equipment types allowed users to choose the best instruments for their application. Respirometry equations, normally a topic of terror and confusion to researchers, were derived and described in sufficient detail to facilitate their selection and use. In this new edition, the content has been thoroughly updated and a decade of new literature incorporated. New chapters on room calorimetry, human metabolic measurement, and metabolic phenotyping have also been added.

Best-selling author Theodore Gray is back with all-new, spectacular experiments that demonstrate basic principles of chemistry and physics in thrilling, and memorable ways.

For nearly a decade, Theodore Gray has been demonstrating basic principles of chemistry and physics through exciting, sometimes daredevil experiments that he executes, photographs, and writes about for his monthly Popular Science column "Gray Matter."

Theo Gray's Mad Science: Experiments You Can Do at Home, But Probably Shouldn't, published by Black Dog in 2009, collected Gray's Popular Science columns, along with hundreds of photographs, many of which were not published with the original columns.

Now comes the second volume of mad-scientist experiments, which includes more dramatic, enlightening, and sometimes daring demonstrations in which Gray dips his hand into molten lead to demonstrate the Leidenfrost effect; crushes a tomato between two small magnets to demonstrate the power of neodymium-iron-boron magnets; and creates trinkets out of solid mercury to demonstrate how the state of matter depends very much on the temperature at which it exists.

Other experiments include:

A foil boat floating on an invisible sea

DIY X-ray photos

A bacon lance that cuts steel

Charging a smart phone with apples and pennies

And dozens more

Proven and tested guidelines for designing ideal labs for scientific investigations

Now in its "Fourth Edition, Guidelines for Laboratory Design "continues to enable readers to design labs that make it possible to conduct scientific investigations in a safe and healthy environment. The book brings together all the professionals who are critical to a successful lab design, discussing the roles of architects, engineers, health and safety professionals, and laboratory researchers. It provides the design team with the information needed to ask the right questions and then determine the best design, while complying with current regulations and best practices.

"Guidelines for Laboratory Design" features concise, straightforward advice organized in an easy-to-use format that facilitates the design of safe, efficient laboratories. Divided into five sections, the book records some of the most important discoveries and achievements in: Part IA, Common Elements of Laboratory Design, sets forth technical specifications that apply to most laboratory buildings and modulesPart IB, Common Elements of Renovations, offers general design principles for the renovation and modernization of existing labsPart II, Design Guidelines for a Number of Commonly Used Laboratories, explains specifications, best practices, and guidelines for nineteen types of laboratories, with three new chapters covering nanotechnology, engineering, and autopsy labsPart III, Laboratory Support Services, addresses design issues for imaging facilities, support shops, hazardous waste facilities, and laboratory storeroomsPart IV, HVAC Systems, explains how to heat, cool, and ventilate labs with an eye towards energy conservationPart V, Administrative Procedures, deals with bidding procedures, final acceptance inspections, and sustainability

The final part of the book features five appendices filled with commonly needed data and reference materials.

This "Fourth Edition" is indispensable for all laboratory design teams, whether constructing a new laboratory or renovating an old facility to meet new objectives.

Dealing with the principles of calibration—both the theoretical and mathematical constructs which relate features of calibration equations to the physical phenomena that affect instruments and samples used on generating information. Among derivations in leading spectroscopic and statistical literature, numerous necessary mathematical derivations have been specifically designed for this book. Covers the practical aspects of generating a calibration equation including how to recognize and deal with various types of problems affecting calibration dataset, relating theoretical ideas, and their affect on data and how to deal with unusual situations.

Starting from first principles, this book introduces the closely related phenomena of Bose condensation and Cooper pairing, in which a very large number of single particles or pairs of particles are forced to behave in exactly the same way, and explores their consequences in condensed matter systems. Eschewing advanced formal methods, the author uses simple concepts and arguments to account for the various qualitatively new phenomena which occur in Bose-condensed and Cooper-paired systems, including but not limited to the spectacular macroscopic phenomena of superconductivity and superfluidity. The physical systems discussed include liquid 4-He, the BEC alkali gases, "classical" superconductors, superfluid 3-He, "exotic" superconductors and the recently stabilized Fermi alkali gases. The book should be accessible to beginning graduate students in physics or advanced undergraduates.

If you're taking a basic course in classical physics, or have a healthy curiosity for the way things work in the physical world, the Illustrated Guide to Home Physics Experiments provides an ideal hands-on introduction to physics lab techniques and data analysis. With this book and a few simple (and inexpensive) tools and materials, you'll learn to conduct experiments that answer questions about our world, make demonstrations to show off physical principles, and do theoretical lab work to discover how the world works. Perfect for do-it-yourselfers, home-schooled high school students, and college students, this book will help you: Learn everything from the basics of motion all the way to particle physics - including energy, thermodynamics, magnetic fields, optics, and much more Take careful measurements of physical phenomena and conduct data analysis Build and perform physics demonstrations that are fascinating and fun Construct computer models to represent aspects of the physical world It's easy to get started. You can build most of the experiments and demonstrations in this book with ordinary household tools, using materials that you can scrounge, borrow, or get free. The most important thing is your willingness to enter the door of discovery that awaits you. The Illustrated Guide to Home Physics Experiments is your key.

Now in full color, "Hematology Techniques and Concepts for Veterinary Technicians, Second Edition" is a thorough update to this introduction to the fundamental concepts of collecting, handling, and preparing hematology samples. Covering the basics of blood composition, cell morphology, and sample collection, handling, and preparation, the book is designed specifically for veterinary technicians and students to gain a full understanding of why each test is performed and ensure accurate test results. In addition to addressing advances in technology, equipment, and test techniques throughout, a new chapter covers automated testing, and a companion website provides review questions and images from the book for download at www.wiley.com/go/voigt.

Key concepts have also been added to each chapter to better promote learning, and terms are now defined throughout the text, with the definitions collected into a glossary. User-friendly and well-illustrated with charts, reference values, algorithms and photomicrographs, "Hematology Techniques and Concepts for Veterinary Technicians, Second Edition" is a key reference for veterinary technicians and veterinary technology students.

Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting. The text first describes good laboratory practices, including quality management, design control of tests and FDA guidelines for laboratory developed tests, and pre-clinical validation study designs. The second focus of the book describes best practices for staffing and training, including cost of testing, staffing requirements, process improvement using Six Sigma techniques, training and competency guidelines and complete training programs for cytogenetic and molecular genetic technologists. The third part of the text provides step-wise standard operating procedures for chromosomal, FISH and microarray-based tests, including pre-analytic, analytic and post-analytic steps in testing, and divided into categories by specimen type, and test-type. All three sections of the book include example worksheets, procedures, and other illustrative examples that can be downloaded from the Wiley website to be used directly without having to develop prototypes in your laboratory. Providing both a wealth of information on laboratory management and molecular and cytogenetic testing, Cytogenetic Laboratory Management will be an essential tool for laboratorians world-wide in the field of laboratory testing and genetics testing in particular. This book gives the essentials of: * Developing and implementing good quality management programs in laboratories * Understanding design control of tests and pre-clinical validations studies and reports * FDA guidelines for laboratory developed tests * Use of reagents, instruments and equipment * Cost of testing assessment and process improvement using Six Sigma methodology * Staffing training and competency objectives * Complete training programs for molecular and cytogenetic technologists * Standard operating procedures for all components of chromosomal analysis, FISH and microarray testing of different specimen types This volume is a companion to Cytogenetic Abnormalities: Chromosomal, FISH and Microarray-Based Clinical Reporting. The combined volumes give an expansive approach to performing, reporting and interpreting cytogenetic laboratory testing and the necessary management practices, staff and testing requirements.

Special Details: Equipment Testing Procedure. Softcover Member and other discounts do not apply to this title.

Kari Byron-former host of the wildly popular, iconic cult classic MythBusters-shows how to crash test your way through life, no lab coat required. Kari Byron's story hasn't been a straight line. She started out as a broke artist living in San Francisco, writing poems on a crowded bus on the way to one of her three jobs. Many curve balls, unexpected twists, and yes, literal and figurative explosions later, and she's one of the world's most respected women in science entertainment, blowing stuff up on national television and getting paid for it! In Crash Test Girl, Kari reveals her fascinating life story on the set of MythBusters and beyond. With her signature gusto and roll-up-your-sleeves enthusiasm, she invites readers behind the duct tape and the dynamite, to the unlikely friendships and low-budget sets that turned a crazy idea into a famously inventive show with a rabid fanbase. The truth is, Mythbusters was never meant to be a science show. But attaching a rocket to a car, riding a motorcycle on water, or lighting 500 pounds of coffee creamer on fire requires a decent understanding of chemistry, physics, and engineering. Thus, the cast and crew brought in the scientific method to work through each problem: Question. Hypothesize. Experiment. Analyze. Conclude. And as Kari came to learn in her own life, not only is the scientific method the best approach for busting myths, it's also the perfect tool for solving everyday issues, including: Career * Love * Creativity * Setbacks * Money * Sexuality * Depression * Bravery Crash Test Girl reminds us that science is for everyone, as long as you're willing to strap in, put on your safety goggles, hit a few walls, and learn from the results. Using a combination of methodical experimentation and unconventional creativity, you'll come to the most important conclusion of all: In life, sometimes you crash and burn, but you can always crash and learn.

Die rasante Entwicklung der Informationstechnologien forciert den Wandel im Gesundheitswesen und damit die neuen Rollenverstandnisse von Patient, Arzt, Gesundheitsdienstleister und Life-Science-Industrie. Die sich anbahnenden Chancen und Risiken im Gesundheitswesen sind so vielseitig, wie das Verstandnis des Begriffes e-Health. In kompakter und verstandlicher Form werden sowohl fundierte Basiskenntnisse vermittelt als auch Praxis-Perspektiven mit Fallbeispielen fur e-Health aufgezeigt.

Spark scientific curiosity from a young age with this six-level course through an enquiry-based approach and active learning. Collins International Primary Science fully meets the requirements of the Cambridge Primary Science Curriculum Framework from 2020 and has been carefully developed for a range of international contexts. The course is organised into four main strands: Biology, Chemistry, Physics and Earth and Space and the skills detailed under the ‘Thinking and Working Scientifically’ strand are introduced and taught in the context of those areas. For each Teacher’s Guide at Stages 1 to 6, we offer: A comprehensive Teacher’s Guide is easy to follow with a clear and consistent lesson plan layout, including built in continuous assessment The Teacher’s Guide Plus ebook includes components such as slideshows, video clips, additional photographs and interactive activities Earth and Space content covers the new curriculum framework Thinking and Working Scientifically deepens and enhances the delivery of Science skills Includes practical activities that don’t require specialist equipment or labs Scaffolding allows students of varying abilities to work with common content and meet learning objectives Supports Cambridge Global Perspectives™ with activities that develop and practise key skills Provides teacher support as part of a set of resources for the Cambridge Primary Science curriculum framework (0097) from 2020 This series is endorsed by Cambridge Assessment International Education to support the new curriculum framework 0097 from 2020.

This textbook helps you to prepare for your next exams and practical courses by combining theory with virtual lab simulations. The "Labster Virtual Lab Experiments" series gives you a unique opportunity to apply your newly acquired knowledge in a learning game that simulates exciting laboratory experiments. Try out different techniques and work with machines that you otherwise wouldn't have access to.In this book, you'll learn the fundamental concepts of basic biochemistry focusing on: Ionic and Covalent Bonds Introduction to Biological Macromolecules Carbohydrates Enzyme Kinetics In each chapter, you'll be introduced to one virtual lab simulation and a true-to-life challenge. Following a theory section, you'll be able to play the relevant simulation that includes quiz questions to reinforce your understanding of the covered topics. 3D animations will show you molecular processes not otherwise visible to the human eye. If you have purchased a printed copy of this book, you get free access to five simulations for the duration of six months. If you're using the e-book version, you can sign up and buy access to the simulations at www.labster.com/springer. If you like this book, try out other topics in this series, including "Basic Biology", "Basic Genetics", and "Genetics of Human Diseases". Please note that the simulations in the book are not virtual reality (VR) but 2D virtual experiments.

This Primer provides an authoritative and easy to read overview of computers and their use in chemistry. It presents the essential basic ideas required to understand and exploit computers as encountered by chemistry students in their studies and in the laboratory at all stages up to and including research level. It gives its readers an insight into the workings of computers and so helps them to use the facilities more effectively.

Cellular immunology is a rapidly moving field in which recent advances have made significant contributions to our understanding of the immune response to infection and malignancy. These in turn, have given rise to new therapeutic opportunities in areas such as vaccines and immunotheraphy. Many investigators have been discourages by the complicated protocols involved in cellular immunological studies, as illustrated, by the meticulous care required for the generation of antigen-specific T-cells. Lymphocytes: A Practical Approach (second edition) contains straight-forward protocols for well- established procedures in the study of lymphocytes including preparation and identification of lymphocytes, immortalization, cell and organ culture, and quantification assays. It also covers the recent technological advances which have revolutionised the field, such as the use of the Interferon-gamma ELISpot assay and peptide-HLA tetrameric assays to quantify antigen-specifidc T-cells directly from peripheral blood, without the need for in vitro culture, and molecular methods for accurate HLA typing.

It has been recognised for many years that power ultrasound has great potential for uses in a wide variety of processes in the chemical and allied industries. Reported applications include cleaning, sterilisation, flotation, drying, degassing, defoaming, soldering, plastic welding, drilling, filtration, homogenisation, emulsification, dissolution, deaggregation of powder, biological cell disruption, extraction, crystallisation and, more recently, as a stimulus for chemical reactions. With the increasing use of power ultrasound in chemistry comes the need for specialist text books covering this emerging discipline. This book is suitable for chemists and chemical engineers at all levels who wish to gain a rapid insight into what is becoming a standard method in the chemical laboratory. It is designed to answer the following questions: What is sonochemistry? Why is it important? What systems are affected by sonochemistry? What are the major applications of this technique? What types of ultrasonic equipment are available? How do the different types of equipment compare? How is the equipment best configured for chemical applications? What parameters can be changed to optimise sonochemical results? What equipment is available for the scale-up of sonochemistry?

As molecular and cellular biologists move toward nano-techniques for performing experiments on single molecules rather than on populations of molecules, a comprehensive manual on how (and why) to carry out such experiments is needed. Single-Molecule Techniques: A Laboratory Manual fills this requirement - it is the first to take researchers who know nothing about single-molecule analyses to the point where they can successfully design and execute appropriate experiments. Geared toward research scientists in structural and molecular biology, biochemistry, and biophysics, the manual will be useful to all who are interested in observing, manipulating, and elucidating the molecular mechanisms and discrete properties of macromolecules. Techniques range from in vivo and in vitro fluorescent-based methods to the use of atomic force microscopy, optical and magnetic tweezers, and nanopores. The book is edited by Paul R. Selvin and Taekjip Ha, two pioneers in the field of experimental biophysics who have made significant contributions to the development and application of single-molecule technologies.