The Oxford Handbook of the History of Physics brings together cutting-edge writing by more than twenty leading authorities on the history of physics from the seventeenth century to the present day. By presenting a wide diversity of studies in a single volume, it provides authoritative introductions to scholarly contributions that have tended to be dispersed in journals and books not easily accessible to the general reader. While the core thread remains the theories and experimental practices of physics, the Handbook contains chapters on other dimensions that have their place in any rounded history. These include the role of lecturing and textbooks in the communication of knowledge, the contribution of instrument-makers and instrument-making companies in providing for the needs of both research and lecture demonstrations, and the growing importance of the many interfaces between academic physics, industry, and the military.

A classic brought up to date with new experiments using the latest methods.
Modern spectroscopic techniques and current research topics make this an incomparable resource for undergraduate and graduate students, presenting a fascinating approach to inorganic chemistry by providing experiments that resemble real research. As a result, students learn to think in a research-oriented fashion and to research together in a group.
The experiments have been thoroughly tested and safety instructions are included, while hazardous substances are replaced by less harmful ones. This new edition also has a special focus on environmentally friendly experiments.

Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.

THIS VOLUME, WHICH IS DESIGNED FOR STAND-ALONE USE IN TEACHING AND RESEARCH, FOCUSES ON QUANTUM CHEMISTRY, AN AREA OF SCIENCE THAT MANY CONSIDER TO BE THE CENTRAL CORE OF COMPUTATIONAL CHEMISTRY. TUTORIALS AND REVIEWS COVER

1. HOW TO OBTAIN SIMPLE CHEMICAL INSIGHT AND CONCEPTS FROM DENSITY FUNCTIONAL THEORY CALCULATIONS,
2. HOW TO MODEL PHOTOCHEMICAL REACTIONS AND EXCITED STATES, AND
3. HOW TO COMPUTE ENTHALPIES OF FORMATION OF MOLECULES.

A FOURTH CHAPTER TRACES CANADIAN RESEARCH IN THE EVOLUTION OF COMPUTATIONAL CHEMISTRY. ALSO INCLUDED WITH THIS VOLUME IS A SPECIAL TRIBUTE TO QCPE.FROM REVIEWS OF THE SERIES

"Reviews in Computational Chemistry proves itself an invaluable resource to the computational chemist. This series has a place in every computational chemist’s library."—Journal of the American Chemical Society

New trends in solid-phase extraction for analytical use—a practical introduction.

Owing to its low cost, ease of use, and nonpolluting means of preparing samples for analysis, solid-phase extraction (SPE) is fast overtaking traditional liquid—liquid methods in clinical, pharmaceutical, agricultural, and industrial applications. This book describes what analytical scientists and technicians need to know about this emerging procedure: how it works, how to choose from available techniques, how to utilize it effectively in the laboratory. Along with the historical perspective and fundamental principles, this practical book reviews the latest literature on solid-phase materials, equipment, and applications—including EPA-endorsed techniques. Special features include:

• Coverage of separation and uptake methods.
• Promising developments in the use of membrane disks.
• The advantages of using polymeric resins over silica materials.
• Mechanism and use of ion-exchange materials for SPE.
• A remarkably complete chapter on the extraction of metal ions.
• Groundbreaking research in the miniaturized SPE technique.

SOLID-PHASE MICROEXTRACTION Theory and Practice Janusz Pawliszyn 1997 (0-471-19034-9) 264 pp.

In Laser Physics the interaction of radiation and matter, and the principles of laser operation are treated at a level suitable for fourth-year undergraduate courses or introductory graduate courses in physics, chemistry or engineering. The factors which determine efficiency, wavelength coverage, output power, and beam quality of the different classes of laser are treated both in terms of fundamental theory and practical construction aspects. Details of established types of solid-state, semiconductor, and gas lasers are examined together with the techniques that enable their output to be converted widely across the spectrum. The latest advances in high power fibre lasers, femtosecond lasers, and X-ray lasers are explained. The text is liberally illustrated with more than 300 diagrams. An extensive bibliography is provided, together with numerical problems in each chapter. Solutions are available via the web.
To request a copy of the Solutions Manual, visit: http: //global.oup.com/uk/academic/physics/admin/solutions

A complete guide to choosing and using the best analytical technique for the job at hand

Today's new generation of spectroscopic instrumentation allows for more accurate and varied measurements than ever before. At the same time, increasingly powerful, user-friendly PC hardware and software make running those instruments relative child's play. However, although they may have solved many of the problems traditionally associated with conducting molecular spectroscopic analyses, these refinements tend to obscure inherent technical challenges which, if not taken into consideration, can seriously undermine a research initiative. Modern Techniques in Applied Molecular Spectroscopy gives scientists and technicians the knowledge they need to address those challenges and to make optimal selection and use of contemporary molecular spectroscopic techniques and technologies.

While editor Francis Mirabella and contributors provide ample background information about how and why individual techniques work, they concentrate on practical considerations of crucial concern to researchers working in industry. For each technique covered, they provide expert guidance on method selection, sample preparation, troubleshooting, data handling and analysis, and more. Adhering principally to mid-IR molecular spectroscopic techniques, they clearly describe the guiding principles behind, characteristics of, and suitable applications for transmission spectroscopy, reflectance spectroscopies, photoacoustic spectroscopy, infrared and Raman microspectroscopy, fiber optic techniques, and emission spectroscopy.

Modern Techniques in Applied Molecular Spectroscopy is an indispensable working resource for analytical scientists and technicians working in an array of industries.

Soaring Gothic cathedrals, violent crusades, the Black Death: these are the dramatic forces that shaped the medieval era. But the so-called Dark Ages also gave us the first universities, eyeglasses, and mechanical clocks. As medieval thinkers sought to understand the world around them, from the passing of the seasons to the stars in the sky, they came to develop a vibrant scientific culture. In The Light Ages, Cambridge science historian Seb Falk takes us on a tour of medieval science through the eyes of one fourteenth-century monk, John of Westwyk. Born in a rural manor, educated in England's grandest monastery, and then exiled to a clifftop priory, Westwyk was an intrepid crusader, inventor, and astrologer. From multiplying Roman numerals to navigating by the stars, curing disease, and telling time with an ancient astrolabe, we learn emerging science alongside Westwyk and travel with him through the length and breadth of England and beyond its shores. On our way, we encounter a remarkable cast of characters: the clock-building English abbot with leprosy, the French craftsman-turned-spy, and the Persian polymath who founded the world's most advanced observatory. The Light Ages offers a gripping story of the struggles and successes of an ordinary man in a precarious world and conjures a vivid picture of medieval life as we have never seen it before. An enlightening history that argues that these times weren't so dark after all, The Light Ages shows how medieval ideas continue to color how we see the world today.

Dealing with the principles of calibration—both the theoretical and mathematical constructs which relate features of calibration equations to the physical phenomena that affect instruments and samples used on generating information. Among derivations in leading spectroscopic and statistical literature, numerous necessary mathematical derivations have been specifically designed for this book. Covers the practical aspects of generating a calibration equation including how to recognize and deal with various types of problems affecting calibration dataset, relating theoretical ideas, and their affect on data and how to deal with unusual situations.

Now in full color, "Hematology Techniques and Concepts for Veterinary Technicians, Second Edition" is a thorough update to this introduction to the fundamental concepts of collecting, handling, and preparing hematology samples. Covering the basics of blood composition, cell morphology, and sample collection, handling, and preparation, the book is designed specifically for veterinary technicians and students to gain a full understanding of why each test is performed and ensure accurate test results. In addition to addressing advances in technology, equipment, and test techniques throughout, a new chapter covers automated testing, and a companion website provides review questions and images from the book for download at www.wiley.com/go/voigt.

Key concepts have also been added to each chapter to better promote learning, and terms are now defined throughout the text, with the definitions collected into a glossary. User-friendly and well-illustrated with charts, reference values, algorithms and photomicrographs, "Hematology Techniques and Concepts for Veterinary Technicians, Second Edition" is a key reference for veterinary technicians and veterinary technology students.

* Internet exercises available on the Web.
* Topics and approach emphasize the development of scientific literacy.
* Written in a clear, easy-to-read style.
* Numerous experiments to choose from cover all topics typically covered in prep chemistry courses.
* Avoids the use of known carcinogens and toxic metal salts.
* Chemical Capsules demonstrate the relevance and importance of chemistry.

Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting. The text first describes good laboratory practices, including quality management, design control of tests and FDA guidelines for laboratory developed tests, and pre-clinical validation study designs. The second focus of the book describes best practices for staffing and training, including cost of testing, staffing requirements, process improvement using Six Sigma techniques, training and competency guidelines and complete training programs for cytogenetic and molecular genetic technologists. The third part of the text provides step-wise standard operating procedures for chromosomal, FISH and microarray-based tests, including pre-analytic, analytic and post-analytic steps in testing, and divided into categories by specimen type, and test-type. All three sections of the book include example worksheets, procedures, and other illustrative examples that can be downloaded from the Wiley website to be used directly without having to develop prototypes in your laboratory. Providing both a wealth of information on laboratory management and molecular and cytogenetic testing, Cytogenetic Laboratory Management will be an essential tool for laboratorians world-wide in the field of laboratory testing and genetics testing in particular. This book gives the essentials of: * Developing and implementing good quality management programs in laboratories * Understanding design control of tests and pre-clinical validations studies and reports * FDA guidelines for laboratory developed tests * Use of reagents, instruments and equipment * Cost of testing assessment and process improvement using Six Sigma methodology * Staffing training and competency objectives * Complete training programs for molecular and cytogenetic technologists * Standard operating procedures for all components of chromosomal analysis, FISH and microarray testing of different specimen types This volume is a companion to Cytogenetic Abnormalities: Chromosomal, FISH and Microarray-Based Clinical Reporting. The combined volumes give an expansive approach to performing, reporting and interpreting cytogenetic laboratory testing and the necessary management practices, staff and testing requirements.

Special Details: Equipment Testing Procedure. Softcover Member and other discounts do not apply to this title.

Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.

Die rasante Entwicklung der Informationstechnologien forciert den Wandel im Gesundheitswesen und damit die neuen Rollenverstandnisse von Patient, Arzt, Gesundheitsdienstleister und Life-Science-Industrie. Die sich anbahnenden Chancen und Risiken im Gesundheitswesen sind so vielseitig, wie das Verstandnis des Begriffes e-Health. In kompakter und verstandlicher Form werden sowohl fundierte Basiskenntnisse vermittelt als auch Praxis-Perspektiven mit Fallbeispielen fur e-Health aufgezeigt.

How do scientists impact society in the twenty-first century? Many scientists are increasingly interested in the impact that their research will have on the public. Scientists likewise must answer the question above when applying for funding from government agencies, particularly as part of the 'Broader Impacts' criterion of proposals to the US National Science Foundation. This book equips scientists in all disciplines to do just that, by providing an overview of the origins, history, rationale, examples, and case studies of broader impacts, primarily drawn from the author's experiences over the past five decades. Beyond including theory and evidence, it serves as a 'how to' guide for best practices for scientists. Although this book primarily uses examples from the NSF, the themes and best practices are applicable to scientists and applications around the world where funding also requires impacts and activities that benefit society.

Cellular immunology is a rapidly moving field in which recent advances have made significant contributions to our understanding of the immune response to infection and malignancy. These in turn, have given rise to new therapeutic opportunities in areas such as vaccines and immunotheraphy. Many investigators have been discourages by the complicated protocols involved in cellular immunological studies, as illustrated, by the meticulous care required for the generation of antigen-specific T-cells. Lymphocytes: A Practical Approach (second edition) contains straight-forward protocols for well- established procedures in the study of lymphocytes including preparation and identification of lymphocytes, immortalization, cell and organ culture, and quantification assays. It also covers the recent technological advances which have revolutionised the field, such as the use of the Interferon-gamma ELISpot assay and peptide-HLA tetrameric assays to quantify antigen-specifidc T-cells directly from peripheral blood, without the need for in vitro culture, and molecular methods for accurate HLA typing.

As molecular and cellular biologists move toward nano-techniques for performing experiments on single molecules rather than on populations of molecules, a comprehensive manual on how (and why) to carry out such experiments is needed. Single-Molecule Techniques: A Laboratory Manual fills this requirement - it is the first to take researchers who know nothing about single-molecule analyses to the point where they can successfully design and execute appropriate experiments. Geared toward research scientists in structural and molecular biology, biochemistry, and biophysics, the manual will be useful to all who are interested in observing, manipulating, and elucidating the molecular mechanisms and discrete properties of macromolecules. Techniques range from in vivo and in vitro fluorescent-based methods to the use of atomic force microscopy, optical and magnetic tweezers, and nanopores. The book is edited by Paul R. Selvin and Taekjip Ha, two pioneers in the field of experimental biophysics who have made significant contributions to the development and application of single-molecule technologies.

This book makes life easier for those developing a computerized experiment. It is full of information to enable scientists and engineers to find their way through the many computing and electronics topics associated with computerized measurement. It draws together the knowledge of several fields in an easy to understand manner, and comes complete with a disk containing all the many useful examples of software and other information listed in the text.

This essential laboratory handbook dispels the mystery surrounding organocopper compounds and offers expert guidance on how to overcome the many problems associated with their use. Authored by leading researchers, the book features clear, practical descriptions of key procedures used in the preparation and application of these highly specific reagents. In addition, the book contains a succinct historical overview of the field's development. Beginning and established researchers alike will find Organocopper Reagents: A Practical Approach an invaluable source of information on an exciting, fast-growing field.

An ideal introduction to this fast growing area, this Primer describes the many computational methods currently used by practising chemists. The authors describe the various techniques available, and how they can be applied to single molecules, to assemblies of molecules, and to molecules undergoing reaction. An introductory chapter outlines hardware and software options, as well as investigating some applications and developments. Subsequent chapters cover quantum mechanics, molecular mechanics, statistical mechanics, the modelling of biomolecules, and drug design.

Plant cell culture techniques are being increasingly used in basic research and for plant exploitation in industry (genetic engineering, micropropagation). In this book, internationally recognized experts describe the techniques in use in their laboratories for isolating and manipulating cell cultures, and their central importance in plant biotechnology.

Die nichtinvasive Erfassung des arteriellen Pulswellensignals erlaubt Pulsmessung, Pulsoximetrie bis hin zu Gefassrisikobewertung direkt am Unterarm. Robert Couronne beschreibt zwei Modellsimulationen der Photonenausbreitung im Unterarmgewebe. Anhand gemessener Intensitaten verifiziert der Autor die erweiterte Lambert-Beer-Beziehung eines planaren Schichtenmodells und untersucht mithilfe eines Zylindermodells die Intensitatsverteilung entlang des Unterarmumfangs, wobei bevorzugte Ableitregionen identifiziert werden. Zum experimentellen Nachweis stellt der Autor den Prototyp eines optisch-transmissiven Mehrkanalsensorsystems vor und zeigt anhand von Probandenmessungen die technische Signalgewinnung und praktische Anwendbarkeit. Mit einem Klassifikationsverfahren kann die automatische Signalidentifikation sowie eine Qualitatsbewertung im Realzeitbetrieb erreicht werden. Die vorgestellten Verfahren sind dabei auf gangigen Mikrocontroller-Plattformen lauffahig."