This book covers the principles of cryopreservation as they relate the preservation of viable cells and cell materials being developed for biopharmaceutical applications. Topics include: the principles of freezing and thawing cells, physiochemical phenomena, process and system design options, method selection considerations, preservation procedures, cryoprotectant additives, freeze-drying human live virus vaccines, and transport system selection criteria. Contributions from well-known experts such as Steven S. Lee, Thomas C. Pringle, William H. Siegel, Richard Wisniewski, and Fangdong Yin make this the single most important study available.

The petrochemical industry is a scientific and engineering field that encompasses the production of a wide range of chemicals and polymers. The purpose of this book is not only to provide a follow-on to form the later chapters of the highly successful Chemistry and Technology of Petroleum 5th Edition but also provides a simplified approach to a very diverse chemical subject dealing with the chemistry and technology of various petroleum and petrochemical process. Following from the introductory chapters, this book provides the readers with a valuable source of information containing insights into petrochemical reactions and products, process technology, and polymer synthesis. Provides readers with a valuable source of information containing insights into petrochemical reactions and products, process technology, and polymer synthesis Introduces the reader to the various petrochemical intermediates are generally produced by chemical conversion of primary petrochemicals to form more complicated derivative products The reactions and processes involved in transforming petroleum-based hydrocarbons into the chemicals that form the basis of the multi-billion dollar petrochemical industry are reviewed and described The book includes information on new process developments for the production of raw materials and intermediates for petrochemicals Includes a description of the origin of the raw materials for the petrochemicals industry - including an overview of the coal chemicals industry

This book is a compilation of the engineering data on mixing, which have appeared in the major technical journals of chemical engineering and bioengineering since 1975. That year marked the beginning of a period of rapid advancement in the science and technology of mixing, with rather reliable results for both theoretical and experimental studies. In addition, some important earlier articles which have been, and still are being referred to, are included.
Designs of both agitators and tanks still depend primarily on art and experience. In light of this it was felt that the data on mixing should be compiled and presented in a systematic manner to assist in design and analysis of agitated tanks, and to provide easier access to mixing data for various engineering activities. Although computer-aided searches of pertinent data bases can be of assistance to chemical engineers and bioengineers in their studies, they are sometimes time-consuming and often costly. Furthermore inadequate selection of key words can jeopardize the searches. This book offers an alternative method of surveying mixing data which interests readers.
The first chapter presents a variety of results for the experimental measurements of flow patterns in stirred tanks. Most of the measurements were made by using modern Laser-Doppler techniques. This chapter is useful for the prediction of flow patterns in tanks with many different geometries, various types of agitators, and fluids of diverse physical and rheological properties, plus valuable data for the validation of results obtained by CFD simulations. Chapters 2 through 5 deal with data for traditional chemical engineering subjects and Chapter 6 summarizes a number of scale-up relations developed over the years for various systems. These include liquid, solid-liquid, liquid-liquid, gas-liquid, and solid-liquid-gas systems. Chapter 7 provides data related to multiphase processes, and most importantly, drop size and drop-size distributions and bubble-size distributions. These two subjects have not been treated systematically either in text books or in handbooks on stirred-tank mixing, although the results of both experimental and theoretical investigations have been reported on many occasions. Finally gas-inducing mechanically agitated systems are dealt with. The applications of this type of agitation system will become increasingly attractive from the standpoint of rationalization of stirred-tank operations as well as environmental protection.

Editors: V.B. Fainerman, G. Loglio, E.H. Lucassen-Reynders, R. Miller and P. Petrov

This monograph provides a comprehensive introduction into the fast developing research field of dynamic processes at liquid/gas and liquid/liquid interfaces to postgraduate students, scientists and engineers interested in the fundamentals of non-equilibrium interfacial properties. It also addresses to some extent application fields, such as foams and emulsions. Theory and experiments on dynamic adsorption layers are considered systematically and discussed with respect to processes at interfaces.
It is both an introduction for beginners in the present field as well as a systematic preparation of a vast range of the current scientific investigations generalised, together with accumulated knowledge for those already being an insider. It is the first extensive review available on the subject of dynamics of adsorption and gives a general summary of the current state of adsorption kinetics theory and experiments. The book also reviews recent progress in new-designed set-ups and improved and generalised known methods for studying interfacial relaxations.

"Serves as a comprehensive introduction to the preparation, uses, and physical chemistry of silicone surfactants--focusing on silicone polyoxyalkylene copolymers that are surface active in both aqueous and nonaqueous systems. Covers applications in the manufacture of polyurethane foam, coatings, wetting agents, fabric finishes, and polymer surface modifiers."

Intended primarily for undergraduate chemical-engineering students, this book also includes material which bridges the gap between undergraduate and graduate requirements. The introduction contains a listing of the principal types of reactors employed in the chemical industry, with diagrams and examples of their use. There is then a brief exploration of the concepts employed in later sections for modelling and sizing reactors, followed by basic information on stoichiometry and thermodynamics, and the kinetics of homogeneous and catalyzed reactions. Subsequent chapters are devoted to reactor sizing and modelling in some simple situations, and more detailed coverage of the design and operation of the principal reactor types.

Discussing the technology and its applications, Membrane Processes: A Technology Guide investigates the differing requirements of industry today. Driven by increasing water quality demands, the technological spotlight is now on the application of membranes to potable water, and several significant examples of filtration processes are given. Encompassing the fundamentals of design and operation of membranes, feasibility of use and economics as well as applications in water, paint and other industries, this coverage of the key aspects of membrane technology will be welcomed by technologists, engineers and scientists in a variety of disciplines.

This edited volume focuses on comprehensive state-of-the-art information about the practical aspects of cultivation, harvesting, biomass processing and biofuel production from algae. Chapters cover topics such as synthetic ecological engineering approaches towards sustainable production of biofuel feedstock, and algal biofuel production processes using wastewater. Readers will also discover more about the role of biotechnological engineering in improving ecophysiology, biomass and lipid yields. Particular attention is given to opportunities of commercialization of algal biofuels that provides a realistic assessment of various techno-economical aspects of pilot scale algal biofuel production. The authors also explore the pre-treatment of biomass, catalytic conversion of algal lipids and hydrothermal liquefaction with the biorefinery approach in detail. In a nut shell, this volume will provide a wealth of information based on a realistic evaluation of contemporary developments in algal biofuel research with an emphasis on pilot scale studies. Researchers studying and working in the areas of environmental science, biotechnology, genetic engineering and biochemistry will find this work instructive and informative.

Volume I contains a brief review of adsorption history and its development for practical purposes up until now. It also presents some important information on adsorbents and catalysts as well as on the methods of their characterization. The part of this volume dealing with practical industrial applications includes chapters presenting advanced technical tools for high capacity adsorption separation of liquid and gas mixtures, development of new adsorbents for removal of hazardous contaminants from combustion flue gases and wastewaters, degasification of coal seams and fabrication of inorganic membranes and their applications. A comprehensive review is also included on contemporary utility of self-assembled monolayers, adsorption proteins and their role in modern industry, adsorption methods in technology of optical fibre glasses, sol-gel technology, solid desiccant dehumidification systems, etc. The articles give both the scientific backgrounds of the phenomena discussed and emphasize their practical aspects.

The chapters give not only brief current knowledge about the studied problems, but are also a source of topical literature on the subject. A comprehensive bibliography on adsorption principles, design data and adsorbent materials for industrial applications for the period 1967-1997 concludes the book.

This new edition follows the original format, which combines a detailed case study - the production of phthalic anhydride - with practical advice and comprehensive background information. Guiding the reader through all major aspects of a chemical engineering design, the text includes both the initial technical and economic feasibility study as well as the detailed design stages. Each aspect of the design is illustrated with material from an award-winning student design project.
The book embodies the "learning by doing" approach to design. The student is directed to appropriate information sources and is encouraged to make decisions at each stage of the design process rather than simply following a design method. Thoroughly revised, updated, and expanded, the accompanying text includes developments in important areas and many new references.

"Viscosity, Heavy Oils to Waste, Hazardous, Legislation"

The proceedings of the VIIth International Symposium on the "Scientific Bases for the Preparation of Heterogeneous Catalysts," are in line with the general scope of this series of events. Emphasis in all Symposia has been on the scientific aspects of the preparation of new and industrial catalysts, or on new methods of preparation, rather than on the catalytic reactions in which such solids are ultimately used. In the present context, the catalytic event itself has only been considered as another, though often decisive, method of catalyst characterization.

Soon after its publication in 1987, the first edition of Ultrafiltration Handbook became recognized as the leading handbook on ultrafiltration technology. Reviews in professional journals praised it as an authoritative and substantive information resource on this technology. Now a completely, updated and expanded edition is available under the title, Ultrafiltration and Microfiltration Handbook.
This practical handbook systematically covers the basics of this technology from its scientific fundamentals to a wide range of industrial applications. The presentation is clear and concise with the emphasis on practical use. Many schematics and micrographs illustrate membranes, equipment and processes. Numerous tables and graphs provide useful data on specifications and performance.
The updated information is useful to all those involved in the use of separation and filtration in industrial processes.

Discusses the laboratory and industrial synthesis of nonionic surfactants. Furnishes exhaustive coverage of the most recent advances in nonionic surfactant organic chemistry. Analyzes a novel class of catalysts for the production of surfactants with highly narrow distributions.

From explanations of laws and regulations to hands-on design and operation-the Handbook has it covered!

Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

This book provides recent developments in sustainable manufacturing ranging from product designing to product delivery. It focuses on key challenges and solutions at various stages such as product design, material selection, material processing, manufacturing and energy consumption to ensure sustainability at every stage of product lifecycle. It further offers solutions to build sustainable product by responsible consumption and production. The role of advanced technologies in sustainable manufacturing is also covered in this book. Given the topics covered, this book will be useful for the researchers and professionals working in the area of mechanical engineering, especially industrial and production engineering.

Gas Separation by Adsorption Processes is a complete treatise on all aspects of adsorptive processes. It covers all fundamental principles as well as process design and simulation of gas adsorption processes for separation and purification. This highly popular book in the field has now been reprinted and made available in paperback form.

Filling a gap in the literature, this book comprehensively reviews catalytic addition reactions of (hetero)aromatic hydrocarbons across carbon-carbon multiple bonds. In so doing, it summarizes both the scope as well as the limitations of different catalyst systems and building blocks, while highlighting their application to the synthesis of pharmaceuticals. Focusing on the latest developments, the team of authors comprising leaders in the field covers such topics as the hydroarylation of olefins, alkyne hydroarylation in the presence of transition metal catalysts, reaction of alkynes with arylboronic acids, and allene hydroarylation, as well as the synthesis of functionalized arenes and heteroaromatics. A must-have for synthetic chemists in academia and industry dealing with catalysis, organometallic chemistry, the synthesis of natural products, fine chemicals, pharmaceuticals, and organic materials.

Inorganic membrane science and technology is a new field of membrane separation technology which until recently was dominated by the earlier field of polymer membranes. Currently the subject is undergoing rapid development and innovation.

The present book describes the fundamental principles of both synthesis of inorganic membranes and membrane supports and also the associated phenomena of transport and separation in a semi-quantitative form.

Features of this book:

- Examples are given which illustrate the state-of-the-art in the synthesis of membranes with controlled properties

- Future possibilities and limitations are discussed

- The reader is provided with references to more extended treatments in the literature

- Potential areas for future innovation are indicated.

By combining aspects of both the science and technology of inorganic membranes this book serves as a useful source of information for scientists and engineers working in this field. It also provides some observations of important investigators who have contributed to the development of this subject.

Offers information necessary for the development of mathematical models and numerical techniques to solve specific drying problems. The book addresses difficult issues involved with the drying equations of numerical analysis, including mesh generation, discretinization strategies, the nonlinear equation set and the linearized algebraic system, convergance criteria, time step control, experimental validation, optimum methods of visualization results, and more.

Contents:
Part 1: myths about technology; pressure vessels must be fitted with relief valves (or bursting discs); if a vessel is exposed to fire, it should be emptied as quickly as possible; accidents are due to human failing, so we should eliminate the human element when we can; if a flammable material has a high flashpoint, it is safe and will not explode; blast walls provide the ultimate protection against explosions; we can remove hazards; the public believe we are making the world a better place; fire is worse than smoke; accidents are due to a coincidence of unlikely events; computers introduce new problems; the most valuable writings on safety are codes and standards. Part 2: myths about management; engineers should respond to market needs; many questions can be answered by substituting numbers in well-established equations; policies lead to action; treating employees, customers and suppliers well is good business in the long run; stress is a major cause of ill-health today. Part 3: myths about toxicology and the environment; we should look for the effects of substances that have not yet been studied; the causes of cancer are environmental; scientists should be held responsible for the results of their actions; we should recycle whenever possible; entropy is increasing all the time; myths in other walks of life; afterthoughts.

Examines all known industrial processes using shape selective zeolites, relating the fundamental principles of zeolite catalysis to their practical application-detailing present and potential uses of shape selective catalysis in petroleum processing, aromatics processing, and alternate fuels. Second Edition contain new, up-to-date, and expanded coverage of: the specific features that make zeolites shape selective the role shape selective catlysis can play providing environmentally clean fuels 12-membered oxygen ring systems mesopore systems catalytic characterization tests acid/metal catalysis selective oxidation catalysis with titanium zeolites the synthesis of ethers the production of hetero-compounds, such as alcohols and glycols paraselective alkylation of basic nitrogen compounds the effects of adding ZSM-5 to the diet of live animals and more.

"Covers all areas of computer-based data acquisition--from basic concepts to the most recent technical developments--without the burden of long theoretical derivations and proofs. Offers practical, solution-oriented design examples and real-life case studies in each chapter and furnishes valuable selection guides for specific types of hardware."

Selenium (Se) is a chemical element of concern due to its toxicity and increasing anthropogenic release to the environment. Se oxyanions, selenite and selenate, are water-soluble, bioavailable and toxic, whereas elemental selenium, Se(0), is solid and less toxic. Nevertheless, Se(0) is potentially harmful as particulate Se(0) has been reported to be bioavailable to bivalves, to fish and also prone to re-oxidation. In the current work we investigated the reduction of selenite and selenate using pure and mixed microbial cultures. A novel strain of Pseudomonas moraviensis showing high Se tolerance was isolated, classified and characterized for the first time. Biogenic Se(0) shows colloidal properties due to its nanosize scale and negatively-charged biopolymer coating. To address the need for efficient solid-liquid separation of biogenic Se(0) prior to environmental discharge, we tested and compared several physical-chemical separation methods. Centrifugation and filtration can be efficiently used for Se(0) separation but they are not feasible at the industrial scale due to prohibitive costs. Alternatively, chemical coagulation by metal salts, e.g. aluminum sulfate and ferric chloride, resulted in high removal rates around 90%. Electrocoagulation reached the highest colloidal Se(0) removal efficiency of 97% when using iron electrodes. In conclusion, biogenic Se(0) must be removed in a biological post-treatment step and several approaches described in this work could be successfully used.