We are honoured to present this collection of selected papers from the International Conference on Mixing and Crystallization, held at the Tioman Island, Malaysia in April, 1998. We are grateful to the editorial board comprising five eminent researchers in the field of mixing and crystallization for their thoughtful review and suggestions. In order to make this book as current as possible some of the papers have been thoroughly revised, which caused some delay in bringing out this edited version. We received necessary support from the Institute of Post Graduate Studies and Research, the University of Malaya and the Special Research Centre for Multiphase Processes, and the University of Newcastle, Australia in organizing this conference. We are indebted to the Institute of Chemical Engineers, United Kingdom, and the Institution of Engineers, Malaysia for their sponsorship. We would like to thank K.C. Lim, Dr. C. Ramakanth and Ms. Zubaidah for their help at the various stages of editing. We would also like to express our gratitude to Professor Mohd. Ali Hashim and Dr. Nafis Ahmed for their help and encouragement. Finally, I would like to thank Kluwer Academic Publishers for publishing this book. Bhaskar Sen Gupta Shaliza Ibrahim University of Malaya, Kuala Lumpur xi CFD MODELLING OF HYDRODYNAMIC CONDITIONS WITHIN THE WAKE OF MIXING IMPELLER BLADES 1 G.D. RIGByl., G. LANE . AND G.M. EVANSl.

The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers!

Microinjection (G. Sczakiel et al.). How to Make Glass Microtools for the Injection of Isolated Plant Sperm Cells into Embryo Sac Cells Using a Microforge (C.J. Keijzer). Application of Confocal Microscopy for the Study of Neuronal Organization in Human Cortical Areas after Microinjection of Lucifer Yellow (P.V. Belichenko et al.). Flourescent Probes (R.W. Horobin, F. RashidDoubell). Flourescent Phospholipids in Membrane and Lipoprotein Research (A. Hermetter et al.). Selection of Flourescent Golgi Complex Probes Using StructureActivity Relationship Models (F. RashidDoubell, R.W. Horobin). WholeCell PatchClamping (B. Van Duijn et al.). Flourescent Analysis of Replication and Intermediates of Chromatin Folding in Nuclei of Mammalian Cells (G. Banfalvi). Autoflourescence in Potato Tuber Phellem (T. Hendriks et al.). Quantitative Localization of HIV Proteins in Mammalian Cells (L.E.A. Amet et al.). Concepts of the Cytometric Approach (S.C. Brown). 14 additional articles. Index.

Encapsulation is a topic of interest across a wide range of scientific and industrial areas, from pharmaceutics to food and agriculture, for the protection and controlled release of various substances during transportation, storage, and consumption. Since encapsulated materials can be protected from external conditions, encapsulation enhances their stability and maintains their viability. This book offers a comprehensive review of conventional and modern methods for encapsulation. It covers various thermal and nonthermal encapsulation methods applied across a number of industries, including freeze drying, spray drying, spray chilling and spray cooling, electrospinning/electrospraying, osmotic dehydration, extrusion, air-suspension coating, pan coating, and vacuum drying. The book presents basic fundamentals, principles, and applications of each method, enabling the reader to gain extended knowledge. The choice of the most suitable encapsulation technique is based on the raw materials, the required size, and the desirable characteristics of the final products.

This book surveys reliability, availability, maintainability and safety (RAMS) analyses of various engineering systems. It highlights their role throughout the lifecycle of engineering systems and explains how RAMS activities contribute to their efficient and economic design and operation. The book discusses a variety of examples and applications of RAMS analysis, including: * software products; * electrical and electronic engineering systems; * mechanical engineering systems; * nuclear power plants; * chemical and process plants and * railway systems. The wide-ranging nature of the applications discussed highlights the multidisciplinary nature of complex engineering systems. The book provides a quick reference to the latest advances and terminology in various engineering fields, assisting students and researchers in the areas of reliability, availability, maintainability, and safety engineering.

This important new book covers recent advancements, innovations, and technologies in industrial biotechnology, specifically addressing the application of various biomolecules in industrial production and in cleaning and environmental remediation sectors. The goal of industrial biotechnology is to develop new techniques and technologies to transform renewable raw materials into chemicals, materials, and fuels by the substitution of fossil fuels. With the increase in the world's population and the resultant growing energy demand, the need for more energy can be successfully met with the advancements in industrial biotechnology. Currently across the globe significant research has been undertaken in the production of cleaner fuels, materials, and semi-synthetic chemicals, with environmental benefits. Developing countries have huge agricultural resources that could be utilized for production of value-added byproducts for the sustainable development of bio-based economy. The book opens with the chapter on the production of exopolysaccharides from halophilic microorganisms, a polymer that is normally very useful in various production sectors of the food, pharmaceutical, and petroleum industries. The book goes on to cover: The production of antimicrobial compounds from alkaliphilic bacteria Thermophilic actinomycetes Food, agro, and pharmaceutical potential and biotechnological applications of biosurfactants, halophiles, cyclodextrin glycosyl transferease, fungal chitinase, proteases, yeasts and yeast products Also covered in the book are the environmental aspects of industrial biotechnology such as the genetic enhancement for biofuel production, the production of biodegradable thermoplastics, advancements in the synthesis of bio-oil, ecofriendly treatment of agro-based lignocelluloses, and anaerobic bio reactors for hydrocarbon remediation. The international roster of chapter authors have been chosen for their renowned expertise and contribution to the various fields of industrial biotechnology. This book is suitable to chemists, biotechnologists from research institutes, academia, and students as well as for industry professionals

This indispensable book describes lubricant additives, their synthesis, chemistry, and mode of action. All important areas of application are covered, detailing which lubricants are needed for a particular application. Laboratory and field performance data for each application is provided and the design of cost-effective, environmentally friendly technologies is fully explored. This edition includes new chapters on chlorohydrocarbons, foaming chemistry and physics, antifoams for nonaqueous lubricants, hydrogenated styrene-diene viscosity modifiers, alkylated aromatics, and the impact of REACh and GHS on the lubricant industry.

PEM Fuel Cell Failure Mode Analysis presents a systematic analysis of PEM fuel cell durability and failure modes. It provides readers with a fundamental understanding of insufficient fuel cell durability, identification of failure modes and failure mechanisms of PEM fuel cells, fuel cell component degradation testing, and mitigation strategies against degradation. The first several chapters of the book examine the degradation of various fuel cell components, including degradation mechanisms, the effects of operating conditions, mitigation strategies, and testing protocols. The book then discusses the effects of different contamination sources on the degradation of fuel cell components and explores the relationship between external environment and the degradation of fuel cell components and systems. It also reviews the correlation between operational mode, such as start-up and shut-down, and the degradation of fuel cell components and systems. The last chapter explains how the design of fuel cell hardware relates to failure modes. Written by international scientists active in PEM fuel cell research, this volume is enriched with practical information on various failure modes analysis for diagnosing cell performance and identifying failure modes of degradation. This in turn helps in the development of mitigation strategies and the increasing commercialization of PEM fuel cells.

This textbook presents a general multi-objective optimization framework for optimizing chemical processes by implementing a link between process simulators and metaheuristic techniques. The proposed approach is general and shows how to implement links between different process simulators such as Aspen Plus (R), HYSIS (R), Super Pro Designer (R) linked to a variety of metaheuristic techniques implemented in Matlab (R), Excel (R), C++, and others, eliminating the numerical complications through the optimization process. Furthermore, the proposed framework allows the use of thermodynamic, design and constitutive equations implemented in the process simulator to implement any process. Aimed at graduate and undergraduate students, it presents introductory chapters for process simulators and metaheuristic optimization techniques and provides several worked exercises as well as proposed exercises. In addition, accompanying tutorial videos clearly explaining the implemented methodologies are available online. Also, some Matlab (R) routines are included as electronic supporting material.

In the past decades, the scan rate range of calorimeters has been extended tremendously at the high end, from approximately 10 up to 10 000 000 DegreesC/s and more. The combination of various calorimeters and the newly-developed Fast Scanning Calorimeters (FSC) now span 11 orders of magnitude, by which many processes can be mimicked according to the time scale(s) of chemical and physical transitions occurring during cooling, heating and isothermal stays in case heat is exchanged. This not only opens new areas of research on polymers, metals, pharmaceuticals and all kinds of substances with respect to glass transition, crystallization and melting phenomena, it also enables in-depth study of metastability and reorganization of samples on an 1 to 1000 ng scale. In addition, FSC will become a crucial tool for understanding and optimization of processing methods at high speeds like injection molding. The book resembles the state-of-the art in Thermal Analysis & Calorimetry and is an excellent starting point for both experts and newcomers in the field.

This book presents specific key natural and artificial systems that are promising biocatalysts in the areas of health, agriculture, environment and energy. It provides a comprehensive account of the state of the art of these systems and outlines the significant progress made in the last decade using these systems to develop innovative, sustainable and environmentally friendly solutions. Chapters from expert contributors explore how natural enzymes and artificial systems tackle specific targets such as: climate change, carbon footprint and economy and carbon dioxide utilisation; nitrogen footprint and fixation and nitrous oxide mitigation; hydrogen production, fuel cells and energy from bacteria; biomass transformation and production of added-value compounds, as well as biosensors development. This book provides an important and inspiring account for the designing of new natural and artificial systems with enhanced properties, and it appeals not only to students and researchers working in the fields of energy, health, food and environment, but also to a wider audience of educated readers that are interested in these up-to-date and exciting subjects.Chapter "Carbon Dioxide Utilisation-The Formate Route" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Due to an increase in the wide-range of chemicals in petrochemical processing industries, as well as frequency of use, there has been a steady rise in flammability problems and other hazards. Hazardous Area Classification in Petroleum and Chemical Plants: A Guide to Mitigating Risk outlines the necessities of explosion protection in oil, gas and chemical industries, and discusses fire and occupancy hazards, extinguishing methods, hazard identification, and classification of materials. This book addresses these issues and concerns and presents a simple hazard identification system to help offset future problems. It offers information on the hazards of various materials and their level of severity as it relates to fire prevention, exposure, and control. The system provides an alerting signal and on-the-spot information to help protect lives in an industrial plant or storage location during fire emergencies. Understanding the hazard helps to ensure that the process equipment is properly selected, installed, and operated to provide a safe operating system. This text also includes a summary of the rules, methods, and requirements for fighting a fire, introduces various hazard identification systems. * Includes a summary of the rules, methods, and requirements needed to extinguish a fire * Introduces various hazard identification systems * Includes concepts for layout and spacing of equipment in process plants The book serves as resource for plant design engineers as well as plant protection and safety personnel in planning for effective firefighting operations.

Hydrostatic Testing, Corrosion, and Microbiologically Influenced Corrosion: A Field Manual for Control and Prevention teaches industry professionals, managers, and researchers how to combat corrosion failure associated with hydrotesting. It discusses how a test liquid must be selected, how corrosion by bacteria should be controlled, and how to eliminate the risk of leakage. Rather than teaching how hydrotests should be conducted, it helps the reader evaluate the quality of a hydrotest that's already been conducted in terms of oxygen scavenger use, biocide testing, inhibitor addition, and water quality and explains the tasks that top and middle management must ensure are taken with respect to corrosion assessment of hydrotesting. The manual also discusses microbiologically influenced corrosion (MIC) as the main corrosion mechanism related to post-hydrotesting and offers essential knowledge on combating this corrosion process. In addition to being a manual for top and middle management on how to deal with corrosion, this book also:

In "Different Dispatches", David Humphries brings together in a new way a diverse group of well-known American writers of the inter-war period including: Willa Cather, Sherwood Anderson, Ernest Hemmingway, Zora Neale Hurston, James Agee and Robert Penn Warren. He demonstrates how these writers engage journalism in creating innovative texts that address mass culture as well as underlying cultural conditions. The book will be of interest to readers approaching these well-known authors for the first time or for scholars grappling with larger issues of cultural production and reception.

Besides being one of the best Clean Coal Technologies, fluidized beds are also proving to be the most practical option for biomass conversion. Although the technology is well established, the field lacks a comprehensive guide to the design and operating principles of fluidized bed boilers and gasifiers. With more than 30 years of research and industrial experience, Prabir Basu answers this pressing need with Combustion and Gasification in Fluidized Beds.

This book is a versatile resource that explains how fluidized bed equipment works and how to use the basic principles of thermodynamics and fluid mechanics in design while providing insight into planning new projects, troubleshooting existing equipment, and appreciating the capabilities and limitations of the process. From hydrodynamics to construction and maintenance, the author covers all of the essential information needed to understand, design, operate, and maintain a complete fluidized bed system. It is a must for clean coal technology as well as for biomass power generation.

Beginning with a general introduction to fossil or biofuel conversion choices, the book surveys hydrodynamics, fundamentals of gasification, combustion of solid fuels, pollution aspects including climate change mitigation, heat transfer in fluidized beds, the design and operation of bubbling and circulating fluidized bed boilers, and various supporting components such as distributor grates, feeding systems, and gas-solid separators.

Industrial Catalysis: Chemistry and Mechanism is an essential textbook for upper-level undergraduate and graduate students with an interest in the underlying concepts of catalysis, industrial organic chemistry and the mechanism of catalysis. For undergraduates it provides an introduction to the basic catalytic principles and industrial processes. Graduate students will find that the book gives an in-depth understanding of the mechanism of catalytic surface intermediates and the practice of modern catalysis research. For the post graduate and industrial chemist involved in catalysis research, it is a valuable reference text as a compendium of mechanisms by which major industrial catalytic processes operate.This unique book fills the gap between basic organic chemistry and fundamental chemical principles of catalysis, and is a must read for students and researchers in the field.

Industrial Catalysis: Chemistry and Mechanism is an essential textbook for upper-level undergraduate and graduate students with an interest in the underlying concepts of catalysis, industrial organic chemistry and the mechanism of catalysis. For undergraduates it provides an introduction to the basic catalytic principles and industrial processes. Graduate students will find that the book gives an in-depth understanding of the mechanism of catalytic surface intermediates and the practice of modern catalysis research. For the post graduate and industrial chemist involved in catalysis research, it is a valuable reference text as a compendium of mechanisms by which major industrial catalytic processes operate.This unique book fills the gap between basic organic chemistry and fundamental chemical principles of catalysis, and is a must read for students and researchers in the field.

Pressure Swing Adsorption is the first book that provides a coherent and concise summary of the underlying science and technology of pressure swing adsorption (PSA) processes at a level understandable to the practising engineer.
PSA has achieved widespread commercial acceptance as the technology of choice for hydrogen purification, air separation and small scale air driers. However, PSA has numerous other actual and potential uses such as the recovery of methane from landfill gas, the production of carbon dioxide and other large scale applications.
Since the design and optimization of a PSA process requires a somewhat mathematical model, two chapters of the book provide in-depth information on equilibrium theory and dynamic numerical simulation. However, this mathematical material will also help the general reader develop an understanding of the principles and strenghts and limitations of various approaches.
PSA engineers, chemical engineers, environmental chemists, academicians and managers who must make informed decisions about purchasing costly PSA systems will find Pressure Swing Adsorption of particular value.

This book provides insight into domino effects in industrial chemical sites and process industries. It is about the integration of safety and security resources to prevent and mitigate domino effects in the process industries. It explains how chemical industrial areas, comprised of various hazardous installations, are susceptible to a chain of undesired events, or domino effects, triggered by accidental events or intentional attacks and then presents solutions to prevent them. Firstly, the book provides a dynamic graph approach to model the domino effects induced by accidental fire or intentional fire, considering the spatial-temporal evolution of fires. Then, a dynamic risk assessment method based on a discrete dynamic event tree is proposed to assess the likelihood of VCEs and the vulnerability of installations, addressing the time dependencies in vapor cloud dispersion and the uncertainty of delayed ignitions. A dynamic methodology based on dynamic graphs and Monte Carlo is provided to assess the vulnerability of individuals and installations exposed to multi-hazards, such as fire, explosion and toxic release during escalation events. Based on these domino effect models, an economic approach is developed to integrate safe and security resources, obtaining the most cost-benefit protection strategy for preventing domino effects. Finally, a resilience-based approach is provided to find out the most cost-resilient way to protect chemical industrial areas, addressing possible domino effects. This integrated approach will be of interest to researchers, industrial engineers, chemical engineers and safety managers and will help professionals to new solutions in the area of safety and security.

This book presents a large number of organic reactions performed under green conditions, which were earlier performed using anhydrous conditions and various volatile organic solvents. The conditions used involve green solvents like water, super critical carbon dioxide, ionic liquids, polymer-supported reagents, polyethylene glycol and perfluorous liquids. A number of reactions have been conducted in solid state without using any solvent. Most of the reactions have been conducted under microwave irradiations and sonication. In large number of reactions, catalysts like phase transfer catalysts, crown ethers and biocatalysts have been used. Providing the protocols that every laboratory should adopt, this book elaborates the principles of green chemistry and discusses the planning and preparations required to convert to green laboratory techniques. It includes applications relevant to practicing researchers, students and environmental chemists. This book is useful for students (graduate and postgraduate), researchers and industry professionals in the area of chemical engineering, chemistry and allied fields.

Chiral titanium complexes are low-cost, low-toxicity and high-efficiency catalysts. Impressive progress on enantioselective titanium-catalysed transformations has been achieved in the past seven years, with exciting new discoveries ranging from basic reactions to novel methodologies. Despite this, the field has not been substantially reviewed since 2008.This book contains up to date research and covers all types of enantioselective transformations using chiral titanium catalysts. It illustrates the economic, health, and environmental benefits of chiral titanium catalysts, showing the types of highly enantioselective reactions that they are able to induce are unlimited.Work presented here is aimed at researchers in organic and catalytic chemistry, and has been carefully curated to encourage future research possibilities.

Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting is the first proprietary manual for cleaning and rehabilitation through pressure-washing, hydro-blasting and ultra high pressure water jetting (UHP). It examines the cleaning, restoration and rehabilitation of statuary and historical structures; manufacturing hardware; and application technologies for residential, commercial and industrial areas, structures and buildings. Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting contains over 450 applications from agricultural, marine, municipal, food processing, paper-pulp, pharmaceutical and cosmetic, industrial and power generating maintenance areas. It includes gear lists to help readers easily identify the appropriate tooling and equipment for each specific application and industry. Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting supplies readers with the tools to create a successful business model for retaining and safeguarding corporate application itineraries. It is a valuable guide for maintenance superintendents, buyers of maintenance services, contractors, field technicians, engineers and architects involved in commercial-industrial cleaning.

Chemical reaction engineering is at the core of chemical engineering education. Unfortunately, the subject can be intimidating to students, because it requires a heavy dose of mathematics. These mathematics, unless suitably explained in the context of the physical phenomenon, can confuse rather than enlighten students. Bearing this in mind, Reaction Engineering Principles is written primarily from a student's perspective. It is the culmination of the author's more than twenty years of experience teaching chemical reaction engineering. The textbook begins by covering the basic building blocks of the subject-stoichiometry, kinetics, and thermodynamics-ensuring students gain a good grasp of the essential concepts before venturing into the world of reactors. The design and performance evaluation of reactors are conveniently grouped into chapters based on an increasing degree of difficulty. Accordingly, isothermal reactors-batch and ideal flow types-are addressed first, followed by non-isothermal reactor operation, non-ideal flow in reactors, and some special reactor types. For better comprehension, detailed derivations are provided for all important mathematical equations. Narrative of the physical context in which the formulae work adds to the clarity of thought. The use of mathematical formulae is elaborated upon in the form of problem solving steps followed by worked examples. Effects of parameters, changing trends, and comparisons between different situations are presented graphically. Self-practice exercises are included at the end of each chapter.

This book introduces several observer-based methods, including: * the sliding-mode observer * the adaptive observer * the unknown-input observer and * the descriptor observer method for the problem of fault detection, isolation and estimation, allowing readers to compare and contrast the different approaches. The authors present basic material on Lyapunov stability theory, HY control theory, sliding-mode control theory and linear matrix inequality problems in a self-contained and step-by-step manner. Detailed and rigorous mathematical proofs are provided for all the results developed in the text so that readers can quickly gain a good understanding of the material. MATLAB (R) and Simulink (R) codes for all the examples, which can be downloaded from http://extras.springer.com, enable students to follow the methods and illustrative examples easily. The systems used in the examples make the book highly relevant to real-world problems in industrial control engineering and include a seventh-order aircraft model, a single-link flexible joint robot arm and a satellite controller. To help readers quickly find the information they need and to improve readability, the individual chapters are written so as to be semi-independent of each other. Robust Oberserver-Based Fault Diagnosis for Nonlinear Systems Using MATLAB (R) is of interest to process, aerospace, robotics and control engineers, engineering students and researchers with a control engineering background.