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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > General

Ethical, Social and Psychological Impacts of Genomic Risk Communication (Hardcover): Ulrik Kihlbom, Mats G. Hansson, Silke... Ethical, Social and Psychological Impacts of Genomic Risk Communication (Hardcover)
Ulrik Kihlbom, Mats G. Hansson, Silke Schicktanz
R3,907 Discovery Miles 39 070 Ships in 12 - 17 working days

This volume presents the ethical implications of risk information as related to genetics and other health data for policy decisions at clinical, research and societal levels. Ethical, Social and Psychological Impacts of Genomic Risk Communication examines the introduction of new types of health risk information based on faster, cheaper and larger sets of genetic or genomic analysis. Synthesizing the results of a five-year interdisciplinary project, it explores the unsolved ethical and social questions around the sharing of this data, such as: What is best practice in risk communication? What are the normative presumptions and ethical consequences of an increased individual responsibility for ones' health? And how does one deal with the gap between the knowledge of risk and the lack of therapeutic options which often exist for complex diseases, such as dementia or some types of cancer? Drawing on contributions from over 20 experts in the field, this collection examines these questions from a liberal bioethics' perspective, advocating for contextual and cultural-sensitive ethical discussions. This book will be of great interest to students and scholars of theoretical and clinical medical ethics, medical sociology, risk communication and ethics of risk, as well as professionals in clinical genetics.

Genetic Ancestry - Our Stories, Our Pasts (Hardcover): Jada Benn Torres, Gabriel A. Torres Colon Genetic Ancestry - Our Stories, Our Pasts (Hardcover)
Jada Benn Torres, Gabriel A. Torres Colon
R1,529 Discovery Miles 15 290 Ships in 12 - 17 working days

Genetic Ancestry focuses on the scientific nature and limitations of genetic ancestry testing. Co-authored by a genetic anthropologist and a cultural anthropologist, it examines the social, historical, and cultural dimensions of how people interpret genetic ancestry data. Utilizing examples from popular culture around the world and case studies from the Caribbean, the chapters highlight how genetic technology can sometimes bolster racial thinking and serve as tool of resistance and social justice.

Stem Cells in the Lung - Development, Repair and Regeneration (Hardcover, 1st ed. 2015): Ivan Bertoncello Stem Cells in the Lung - Development, Repair and Regeneration (Hardcover, 1st ed. 2015)
Ivan Bertoncello
R5,527 Discovery Miles 55 270 Ships in 12 - 17 working days

This book presents a comprehensive overview of the current understanding of the organization of endogenous lung stem and progenitor cell compartments during fetal lung development, postnatal lung growth and in adulthood. Progressing stage by stage, the chapters on fetal lung development emphasize the integrated role of epithelial, stromal, vascular and neural cell elements in building a functional lung, while the subsequent chapters on adult lung regeneration describe the nature and properties of adult lung stem/progenitor cells distributed along the proximal-distal axis of the airway tree. The chapters on regulation of lung regeneration and repair discuss how regenerative cells interact with their niche microenvironment and how regulation of lung regeneration and repair in the steady state and following injury recapitulates ontogeny. And, lastly, the chapters on cellular therapies for lung disease and bioengineering the lung focus on promising emerging therapies and approaches in lung regenerative medicine. The scope of this volume of the Stem Cell Biology and Regenerative Medicine series focuses on exploring the topic of building and rebuilding the lung from a cellular rather than a molecular perspective. Thus, the section on cellular therapies does not include extensive coverage of each of the numerous lung diseases, including cancer, which could be amenable to stem cell-based therapies, although the final chapter does include some discussion on the future prospects and challenges. All of the contributors are working on the cutting edge of the lung stem cell field, making this book essential reading for those with an interest in the field of lung stem cell biology and the potential role of cellular therapies and tissue bioengineering approaches in lung regenerative medicine, including biomedical scientists, graduate students, post-graduate researchers and respiratory clinicians.

From Proteins to Proteomics - Basic Concepts, Techniques, and Applications (Hardcover): Sanjeeva Srivastava From Proteins to Proteomics - Basic Concepts, Techniques, and Applications (Hardcover)
Sanjeeva Srivastava
R3,467 Discovery Miles 34 670 Ships in 12 - 17 working days

Basics of proteins and proteomics techniques In-depth understanding of mass-spectrometry and quantitative proteomics An overview of interactomics and its application for translational research. Advancement in the field of proteomics and challenges in clinical applications.

Diagnostics and Gene Therapy for Human Genetic Disorders (Hardcover): K. V. Chaitanya Diagnostics and Gene Therapy for Human Genetic Disorders (Hardcover)
K. V. Chaitanya
R3,494 Discovery Miles 34 940 Ships in 12 - 17 working days

1. Blend of classical human genetics with molecular and genome-based applications 2. Techniques applied for the diagnosis of the genetic disorders 3. Diagnostics of 19 genetic disorders including symptoms, etiology, diagnosis, and treatment. 4. Role of gene therapy in the amelioration of disorders 5. Type studies describing the role of diagnostics in conserving the human health.

Biological Identity - Perspectives from Metaphysics and the Philosophy of Biology (Hardcover): Anne Sophie Meincke, John Dupre Biological Identity - Perspectives from Metaphysics and the Philosophy of Biology (Hardcover)
Anne Sophie Meincke, John Dupre
R4,054 Discovery Miles 40 540 Ships in 12 - 17 working days

Analytic metaphysics has recently discovered biology as a means of grounding metaphysical theories. This has resulted in long-standing metaphysical puzzles, such as the problems of personal identity and material constitution, being increasingly addressed by appeal to a biological understanding of identity. This development within metaphysics is in significant tension with the growing tendency amongst philosophers of biology to regard biological identity as a deep puzzle in its own right, especially following recent advances in our understanding of symbiosis, the evolution of multi-cellular organisms and the inherently dynamical character of living systems. Moreover, and building on these biological insights, the broadly substance ontological framework of metaphysical theories of biological identity appears problematic to a growing number of philosophers of biology who invoke process ontology instead. This volume addresses this tension, exploring to what extent it can be dissolved. For this purpose, the volume presents the first selection of essays exclusively focused on biological identity and written by experts in metaphysics, the philosophy of biology and biology. The resulting cross-disciplinary dialogue paves the way for a convincing account of biological identity that is both metaphysically constructive and scientifically informed, and will be of interest to metaphysicians, philosophers of biology and theoretical biologists.

Phylogenomics - A Primer (Paperback, 2nd edition): Rob Desalle, Michael Tessler, Jeffrey Rosenfeld Phylogenomics - A Primer (Paperback, 2nd edition)
Rob Desalle, Michael Tessler, Jeffrey Rosenfeld
R2,604 Discovery Miles 26 040 Ships in 12 - 17 working days

Phylogenomics: A Primer, Second Edition is for advanced undergraduate and graduate biology students studying molecular biology, comparative biology, evolution, genomics, and biodiversity. This book explains the essential concepts underlying the storage and manipulation of genomics level data, construction of phylogenetic trees, population genetics, natural selection, the tree of life, DNA barcoding, and metagenomics. The inclusion of problem-solving exercises in each chapter provides students with a solid grasp of the important molecular and evolutionary questions facing modern biologists as well as the tools needed to answer them.

An Interplay of Cellular and Molecular Components of Immunology (Hardcover): Indrakant Kumar Singh, Poonam Sharma An Interplay of Cellular and Molecular Components of Immunology (Hardcover)
Indrakant Kumar Singh, Poonam Sharma
R3,499 Discovery Miles 34 990 Ships in 12 - 17 working days

Key Features of the book: Simple, direct, and lucid language. Comprehensive coverage of concepts for better understanding. Well labeled illustrations, flowcharts, and tables for enhanced learning. Every chapter is followed up with a detailed summary and questionnaire. Detailed Glossary at end of the book for users to know the right words. Chapters contributed/reviewed by experienced experts in this field.

Advances in Plant Nitrogen Metabolism (Hardcover): Peerzada Yasir Yousuf, Peerzada Arshid Shabir, Khalid Rehman Hakeem Advances in Plant Nitrogen Metabolism (Hardcover)
Peerzada Yasir Yousuf, Peerzada Arshid Shabir, Khalid Rehman Hakeem
R3,190 Discovery Miles 31 900 Ships in 12 - 17 working days

1. Discusses the effects of environmental stresses on nitrogen metabolism 2. Useful for people doing research in plant physiologists, plant biochemists, geneticists, molecular biologists, agronomists, environmental researchers 3. Details the significant advances that have been made in understanding the physiological, biochemical, and molecular aspects of nitrogen metabolism and its regulation in plants

Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R (Paperback): Hongmei Zhang Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R (Paperback)
Hongmei Zhang
R2,054 Discovery Miles 20 540 Ships in 12 - 17 working days

Analyzing high-dimensional gene expression and DNA methylation data with R is the first practical book that shows a ``pipeline" of analytical methods with concrete examples starting from raw gene expression and DNA methylation data at the genome scale. Methods on quality control, data pre-processing, data mining, and further assessments are presented in the book, and R programs based on simulated data and real data are included. Codes with example data are all reproducible. Features: * Provides a sequence of analytical tools for genome-scale gene expression data and DNA methylation data, starting from quality control and pre-processing of raw genome-scale data. * Organized by a parallel presentation with explanation on statistical methods and corresponding R packages/functions in quality control, pre-processing, and data analyses (e.g., clustering and networks). * Includes source codes with simulated and real data to reproduce the results. Readers are expected to gain the ability to independently analyze genome-scaled expression and methylation data and detect potential biomarkers. This book is ideal for students majoring in statistics, biostatistics, and bioinformatics and researchers with an interest in high dimensional genetic and epigenetic studies.

Reinforcement Sensitivity Theory - A Metatheory for Biosocial Criminology (Paperback): Anthony Walsh Reinforcement Sensitivity Theory - A Metatheory for Biosocial Criminology (Paperback)
Anthony Walsh
R1,240 Discovery Miles 12 400 Ships in 12 - 17 working days

Some of the brightest minds in criminology who were nurtured on the strictly environmentalist paradigm of the 20th century have declared that biosocial criminology is the paradigm for the 21st century. This book attempts to unite this ever-growing field with the premier neurobiological theory of personality, otherwise known as reinforcement sensitivity theory (RST). Anthony Walsh places the highly variable number of biosocial approaches under a single theoretical umbrella, whilst providing a unique integrative framework. As the leading neurobiological theory of personality and behavior in psychology today, RST focuses around the age-old question of how naturally selfish social animals can achieve their wants and needs without alienating others in their social groups. RST posits that evolution has built into humans three interacting systems: the behavioral approach system; the behavioral inhibition system; and the fight/flight/freeze system. RST identifies the neurobiological and genetic functions underlying each system and has found a cascade of supporting evidence. Throwing new light on many areas of concern to criminologists, such as psychopathy, violence, ADHD, and schizophrenia, this book will be of interest to scholars and upper-level students in the field. Additional features such as Focus Boxes and diagrams delve into measurement techniques and brain areas.

Biotechnology - the Science, the Products, the Government, the Business (Hardcover): Ronald P. Evens Biotechnology - the Science, the Products, the Government, the Business (Hardcover)
Ronald P. Evens
R5,079 Discovery Miles 50 790 Ships in 12 - 17 working days

The over-riding premise for biotechnology in this book is bringing novel products to market to substantially advance patient care and disease mitigation. Biotechnology, over its relatively brief existence of 40 years, has experienced a mercurial growth. The vast educational need for biotechnology information in this rapidly burgeoning field is a basic rationale here. However a more prominent underpinning is that, bringing biotech products to market for patient care involves success in the following four areas of engagement simultaneously - scientific advances for healthcare technologies, novel and varied products for untreated diseases, regulatory authorities, and biotech companies. Features Comprehensive coverage of biotechnology science topics used in development and manufacturing Addresses all the scientific technologies within biotechnology responsible for products on the market and the pipeline Presents business issues such as marketing and sales of the products, as well as companies engaged, and how biotech business has evolved

Yeast Functional Genomics - Methods and Protocols (Hardcover, 1st ed. 2016): Frederic Devaux Yeast Functional Genomics - Methods and Protocols (Hardcover, 1st ed. 2016)
Frederic Devaux
R4,553 Discovery Miles 45 530 Ships in 10 - 15 working days

This volume provides a collection of protocols for the study of DNA-DNA contact maps, replication profiles, transcription rates, RNA secondary structures, protein-RNA interactions, ribosome profiling and quantitative proteomes and metabolomes. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Yeast Functional Genomics: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Evolution, Development and Ecology of Anemonefishes - Model Organisms for Marine Science (Hardcover): Vincent Laudet, Timothy... Evolution, Development and Ecology of Anemonefishes - Model Organisms for Marine Science (Hardcover)
Vincent Laudet, Timothy Ravasi
R3,492 Discovery Miles 34 920 Ships in 12 - 17 working days

Contains basic and up-to-date information on an emerging fish model Allows non-specialist readers to grasp the relevance of a wide research area Provides accurate and easy to access information on each of the 30 species Includes guidance for establishing a breeding colony Documents that Anemonefishes are useful model organisms for ecological, developmental and climate research

Stem Cells: Basics and Clinical Translation (Hardcover, 1st ed. 2015): Robert Chunhua Zhao Stem Cells: Basics and Clinical Translation (Hardcover, 1st ed. 2015)
Robert Chunhua Zhao
R5,712 Discovery Miles 57 120 Ships in 12 - 17 working days

This book provides a comprehensive review of the properties of various stem cell types, the mechanisms of their behaviors and their potential clinical application. Stem cells have a great capacity of self-renewal and differentiation. They represent new paradigms for disease treatment in the field of regenerative medicine since the day they were discovered. As stem cell research is complicated and making progress rapidly, it is important to have expertise in this field to share their views and perspectives. This book provides a wonderful platform for those who are interested in stem cells to learn from and communicate with experts. Particularly, it highlights the roles of stem cell based therapy for a variety of diseases. Furthermore, this book gives a detailed introduction to the great works related to stem cells in China. The readers could gain a profound knowledge of the state-of-art research done by scientists in the field of stem cells. Overall, this book will be a valuable reference resource for both experienced investigators pursuing stem cell research as well as those are just entering into this field. Dr. Robert Chunhua Zhao, a Cheung Kong Professor of Stem Cell Biology, is Professor of Cell Biology at the Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College (PUMC), Beijing, China. He is Director of the Center for Tissue Engineering, PUMC and Chief Scientist of the National Basic Research Program of China ("973 Program"). He also serves as Regional Editor of Stem Cells and Development.

Gene-Mapping Techniques and Applications (Paperback): Lawrence B. Schook Gene-Mapping Techniques and Applications (Paperback)
Lawrence B. Schook
R1,284 Discovery Miles 12 840 Ships in 12 - 17 working days

This book explains current strategies for mapping genomes of higher organisms and explores applications of gene mapping to agriculturally important species of plants and animals. It also explores the experimental techniques used for genetic and physical mapping of genes.

Transcription Factors (Paperback): Joseph Locker Transcription Factors (Paperback)
Joseph Locker
R1,870 Discovery Miles 18 700 Ships in 12 - 17 working days

Transcription factors are important in regulating gene expression, and their analysis is of paramount interest to molecular biologists studying this area. This book looks at the basic machinery of the cell involved in transcription in eukaryotes and factors that control transcription in eukaryotic cells. It examines the regulatory systems that modulate gene expression in all cells,a s well as the more specialized systems that regulate localized gene expression throughout the mammalian organism. Transcription Factors updates classical knowledge with recent advances to provide a full and comprehensive coverage of the field for postgraduates and researchers in molecular biology involved in the study of gene regulation.

Genetic Engineering Fundamentals - An Introduction to Principles and Applications (Paperback): John Kammermeyer Genetic Engineering Fundamentals - An Introduction to Principles and Applications (Paperback)
John Kammermeyer
R1,794 Discovery Miles 17 940 Ships in 12 - 17 working days

This important reference/text provides technologists with the basic informationnecessary to interact scientifically with molecular biologists and get involved in scalinguplaboratory procedures and designing and constructing commercial plants.Requiring no previous training or experience in biology, Genetic EngineeringFundamentals explains the biological and chemical principles of recombinant DNAtechnology ... emphasizes techniques used to isolate and clone specific genes frombacteria, plants, and animals, and methods of scaling-up the formation of the geneproduct for commercial applications ... analyzes problems encountered in scaling-upthe microprocessing of biochemical procedures . .. includes an extensive glossary andnumerous illustrations ... identifies other resource materials in the field ... and more.Presenting the fundamentals of biochemistry and molecular biology to workers andstudents in other fields, this state-of-the-art reference/text is essentiai reading fortechnologists in chemistry and engineering; biomedical, chemical, electrical andelectronics, industrial, mechanical, manufacturing, design, plant, control, civil, genetic,and environmental engineers; chemists, botanists, and zoologists; and advancedundergraduate and graduate courses in engineering, biotechnology, and industrialmicrobiology.

DNA Methyltransferases - Role and Function (Hardcover, 1st ed. 2016): Albert Jeltsch, Renata Z. Jurkowska DNA Methyltransferases - Role and Function (Hardcover, 1st ed. 2016)
Albert Jeltsch, Renata Z. Jurkowska
R7,952 Discovery Miles 79 520 Ships in 12 - 17 working days

DNA methyltransferases are important enzymes in a broad range of organisms. Dysfunction of DNA methyltransferases in humans leads to many severe diseases, including cancer. This book focuses on the biochemical properties of these enzymes, describing their structures and mechanisms in bacteria, humans and other species, including plants, and also explains the biological processes of reading of DNA methylation and DNA demethylation. It covers many emerging aspects of the biological roles of DNA methylation functioning as an essential epigenetic mark and describes the role of DNA methylation in diseases. Moreover, the book explains modern technologies, like targeted rewriting of DNA methylation by designed DNA methyltransferases, as well as technological applications of DNA methyltransferases in DNA labelling. Finally, the book summarizes recent methods for the analysis of DNA methylation in human DNA. Overall, this book represents a comprehensive state-of-the-art- work and is a must-have for advanced researchers in the field of DNA methylation and epigenetics.

Population Genetics 2e (Hardcover, 2nd Edition): M.B. Hamilton Population Genetics 2e (Hardcover, 2nd Edition)
M.B. Hamilton
R2,442 Discovery Miles 24 420 Ships in 12 - 17 working days

Now updated for its second edition, Population Genetics is the classic, accessible introduction to the concepts of population genetics. Combining traditional conceptual approaches with classical hypotheses and debates, the book equips students to understand a wide array of empirical studies that are based on the first principles of population genetics. Featuring a highly accessible introduction to coalescent theory, as well as covering the major conceptual advances in population genetics of the last two decades, the second edition now also includes end of chapter problem sets and revised coverage of recombination in the coalescent model, metapopulation extinction and recolonization, and the fixation index.

Protein Arrays, Biochips and Proteomics - The Next Phase of Genomic Discovery (Paperback): Joanna S. Albala, Ian Humphery-Smith Protein Arrays, Biochips and Proteomics - The Next Phase of Genomic Discovery (Paperback)
Joanna S. Albala, Ian Humphery-Smith
R1,883 Discovery Miles 18 830 Ships in 12 - 17 working days

From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein-protein interactions, structural proteomics, and the proteomic marketplace for comprehensive understanding of past, present, and future proteomic research. Offering an abundance of figures and charts, the book compiles a wide variety of technologies and applications ranging from functionalized chip surfaces to strategies for protein expression.

Comparative Genomics and Proteomics in Drug Discovery - Vol 58 (Paperback): Kevin Coward, John Parrington Comparative Genomics and Proteomics in Drug Discovery - Vol 58 (Paperback)
Kevin Coward, John Parrington
R1,848 Discovery Miles 18 480 Ships in 12 - 17 working days

Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds.

Virus Detection (Paperback): Charles H. Wick Virus Detection (Paperback)
Charles H. Wick
R1,113 Discovery Miles 11 130 Ships in 9 - 15 working days

Viruses do not behave as other microbes; their life cycles require infecting healthy cells, commandeering their cellular apparatus, replicating and then killing the host cell. Methods for virus detection and identification have been developed only in the past few decades. These recently developed methods include molecular, physical, and proteomic techniques. All these approaches (Electron Microscopy, Molecular, Direct Counting, and Mass Spectrometry Proteomics) to detection and identification are reviewed in this succinct volume. It is written in approachable language with enough detail for trained professionals to follow and want to recommend to others. Key Features Covers common detection methods Reviews the history of detection from antiquity to the present Documents the strengths and weaknesses of various detection methods Describes how to detect newly discovered viruses Recommends specific applications for clinical, hospital, environmental, and public health uses

Protecting Traditional Knowledge - The WIPO Intergovernmental Committee on Intellectual Property and Genetic Resources,... Protecting Traditional Knowledge - The WIPO Intergovernmental Committee on Intellectual Property and Genetic Resources, Traditional Knowledge and Folklore (Paperback)
Daniel F. Robinson, Ahmed Abdellatif, Pedro Roffe
R1,278 Discovery Miles 12 780 Ships in 12 - 17 working days

This is the first comprehensive review of the Intergovernmental Committee (IGC) of the World Intellectual Property Organization (WIPO) established in 2000. It provides an in-depth consideration of the key thematic areas within WIPO discussions - genetic resources (GRs), traditional knowledge (TK) and traditional cultural expressions (TCEs) through the perspectives of a broad range of experts and stakeholders, including indigenous peoples and local communities. It also looks at how these areas have been treated in a number of forums and settings (including national systems and experiences, and also in trade agreements) and the interface with WIPO discussions. Furthermore, the book analyses the process and the negotiation dynamics since the IGC received a mandate from WIPO members, in 2009, to undertake formal text-based negotiations towards legal instruments for the protection of GR, TK and TCEs. While there has been some progress in these negotiations, important disagreements persist. If these are to be resolved, the adoption of these legal instruments would be a significant development towards resolving key gaps in the modern intellectual property system. In this regard, the book considers the future of the IGC and suggests options which could contribute towards achieving a consensual outcome.

Our Animal Connection - What Sapiens Can Learn from Other Species (Hardcover): Michael Hehenberger, Zhi Xia Our Animal Connection - What Sapiens Can Learn from Other Species (Hardcover)
Michael Hehenberger, Zhi Xia
R1,935 Discovery Miles 19 350 Ships in 12 - 17 working days

This book covers the many ways humans benefit from interactions with other living species. By studying animals of all kinds and sizes, from microbial organisms to elephants and whales, we can learn about their adaptations to extreme conditions on the planet Earth, about the evolutionary development of specialized capabilities, and about their ways of defending themselves against predators and diseases. The authors discuss the strengths and weaknesses of Homo sapiens, and how the study of animals can make us stronger and healthier. To deepen our knowledge of genetics, molecular and cell biology, physiology and medicine, we need to study model organisms. To cure human disease, we can learn from animals how they have evolved ways to protect themselves. To improve human performance, we can study the animal kingdom's top performers and learn from their successes. Considering these important pointers, the authors review genetic engineering techniques that can translate our existing and future animal connections into benefits for human health and performance.

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