This superbly illustrated book is the most comprehensive available guide to adnexal neoplasms of the skin. More than 70 entities are described in individual chapters that follow a uniform structure: historical review, clinical features, histopathology, histogenesis, immunohistochemistry, molecular anomalies, and treatment. Readers will find state of the art knowledge on all aspects, including the cytogenetic and chromosomal abnormalities associated with each neoplasm. Without exception, the illustrations are high-quality, full-color, original digital pictures. The histopathology images are taken from perfectly cut and stained sections and the immunohistochemistry illustrations are of an unrivalled quality among textbooks of dermatology and dermatopathology. A complete list of references from original description to the present day is also supplied for each neoplasm. Cutaneous adnexal neoplasms are a large and heterogeneous group of benign and malignant lesions. This book will assist the reader in early and correct recognition, which is essential for appropriate choice of treatment and prognostic assessment.

Taking advantage of the accessibility of the skin "in vivo," non-invasive methods were developed about 40 years ago, which have now developed as accurate sources to measure skin properties and structures at the microscopic and macroscopic levels. However, even at the dawn of the twenty-first century, the mechanisms involved in these properties are still only partly understood. As in many domains, including biomedical engineering, numerical modeling has appeared as a complementary key actor for improving our knowledge on skin physiology.

This book gathers, for the first time, chapters describing scientific computing and numerical modeling for a deeper understanding of mechanisms involved in skin physiology. The book is structured around some skin properties and functions, including optical and biomechanical properties, skin barrier function, and homeostasis, covered through several chapters describing either biological or physical models at different scales.

This series is intended particularly for young doctors working in hospitals and in primary care and for those involved in training them. The series has been designed to cover growing points in medicine and the authors have been chosen, not just because of their expertise, but also because they are working both in hospitals and the community and are thus sensitive to the problems and needs of doctors in both areas.

The book is not intended to be an all-encompassing atlas or textbook but rather a foundation of principles in dermatopathology, highlighting key elements in the field for trainees and will also serve as a basic resource for the pathologist in general practice. In addition to the sketches and minimal text, we envision accompanying high resolution histopathologic micrographs for ultimate correlation as well.

This is an invaluable collection of information designed to help residents, fellows, and students - as well as any already qualified medical professional interested in revising the essentials of skin conditions - to master the basics of skin pathology. Using the principle of pattern recognition, it simplifies the multitude of dermatopathologic signs by using easy-to-memorize images of what the key features look like - photomnemonics. There are also helpful sections on the technical aspects of dermatopathology and on the key findings at each level of the skin. Organized simply and abundantly illustrated, this text will be an indispensable guide to revision for all its readers.

A must-have reference for any researcher or scientist interested in cutaneous protective mechanisms, this guide provides expertly researched chapters on every aspect of stratum corneum structure, function, and development, as well as detailed sections on barrier-repair strategies and the role of barrier function in diseases such as atopic dermatitis, psoriasis, and ichthyosis.

Achieving the best aesthetic results in Mohs and other cutaneous surgery requires proper patient selection, careful surgical technique, and meticulous postoperative care. Yet despite the best efforts of both surgeon and patient, complications may develop, sometimes resulting in suboptimal or objectionable scarring. Mohs and Cutaneous Surgery: Maximizing Aesthetic Outcomes describes in detail the techniques and procedures that help achieve the most aesthetic results in cutaneous surgery. The book covers wound healing, surgical planning, intraoperative techniques, and complications. Also covered are surgical scar revision, dermabrasion, laser scar revision, neuromodulators and fillers, as well as topical and intralesional therapies for the improvement of scars.

This comprehensive, definitive, and long overdue reference deals specifically with all the manifestations of latex intolerance including irritation, allergic contact dermatitis, and contact urticaria. Each chapter presents the latest research in skin irritation, contact dermatitis, and contact urticaria. The well-illustrated textbook also covers in-depth basic science and clinically relevant practical issues such as the management of latex intolerance and hand dermatitis. Experts with a special interest in this area from the UK, Europe, and the US provide a balanced international perspective to this first major book dedicated to latex intolerance.

Presents authoritative state-of-the-art discussions of the key issues pertinent to transdermal drug delivery, examining those topics necessary to enable a critical evaluation of a drug candidate's potential to be delivered across the skin; from physical chemistry and assessment of drug permeability to available enhancement technolgies, to regulatory approval.

This truly comprehensive reference, in a mini-series format with five volumes, offers a detailed description of both well-known and recently introduced methods for percutaneous penetration enhancement. The first three volumes are devoted to the broad range of chemical methods used to enhance the skin delivery of drugs, including the vast variety of chemical penetration enhancers, drug and vehicle manipulation strategies, nanocarriers, and many others. The fourth volume discusses the diverse physical methods used in penetration enhancement, such as sonophoresis, iontophoresis, electroporation, microporation, laser ablation, and microneedles. Determination of drug penetration is covered in the final volume, with a focus especially on mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. This edition of Percutaneous Penetration Enhancers will be an invaluable resource for researchers, pharmaceutical scientists, practitioners, and also students.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

It is estimated that 80 percent of women have some degree of cellulite. Although there are no permanent solutions for cellulite, dermatologists recognize that this is an issue of importance for many women. This guide reviews current research on the pathophysiology and treatment of cellulite, as well as the many recent developments in medical therapy, liposculpture, and pharmacy to combat the appearance of cellulite in the female figure.

Publications on aesthetic rejuvenation often start with the treatment-such as fillers or lasers-and then work back to the patient problem. Comprehensive Aesthetic Rejuvenation: A Regional Approach starts from the perspective of what the patient perceives as the problem region of the body. It then moves to the appropriate range of treatments that can be offered and discusses how outcomes can be improved. Topics include: The new growth agent for eyelashes Multimodal approaches to healthy skin Aesthetic considerations in ethnic skin Hair loss and transplantation New developments in less invasive fat and cellulite treatments Body contouring surgery Enhanced with more than 200 color illustrations, this volume is an essential resource for all aesthetic and plastic surgeons.

Expertly distinguish viral diseases from other infectious or noninfectious diseases and choose the most effective treatment with this definitive Second Edition. The only existing text to address issues of skin manifestations of viral disease, Mucocutaneous Manifestations of Viral Diseases explores the diagnosis, treatment, and pathogenesis of viral diseases that infiltrate the skin and affiliated mucous membranes. Readers will find new information on: the new controversial HPV vaccines the latest laboratory finding diseases previously known only in developing countrie ocular and oral manifestations of viral diseas manifestations of prion infection common diseases (all variations of human herpes, hepatitis, pox, etc. rare diseases (Crimean-Congo virus, Junin, Dengue fever, etc.) Organized by specific disease, each chapter in this user-friendly text includes: a timeline of infection and pathogenesis of the diseas a brief taxonomy and history of the diseas tabular information to be used for quick reference by the physician color illustrations of epidermal and cellular manifestation methods of differential diagnosi disease incidence among gender and age groups by geographical regio specific antiviral and prophylaxis recommendations laboratory findings and lab tests used to confirm diagnosis and specific antiviral drugs and vaccines treatment/prophylaxis methods

This issue of Dermatologic Clinics, guest edited by Drs. Shari Lipner will cover a number of important topics related to Nail Disorders. This issue is one of four each year selected by longtime series Consulting Editor, Dr. Bruce Thiers. Topics discussion include, but are not limited to: Nails and Systemic Disease, Pediatric Nail Disorders, Bacterial and Viral Infections of the Nail Unit, Nail Psoriasis, Lichen Planus, Diagnosis of Melanonychia, Management of Nail Unit Melanoma, Nail Tumors, Dermoscopy of the Nail Unit, Nail Surgery, Pathology of the Nail Unit, Nail Imaging, Nail Cosmetics, and Nail psoriasis in the elderly, among others.

In this issue of Dermatologic Clinics, guest editor Dr. Kelly M. Cordoro brings her considerable expertise to the topic of Pediatric Dermatology. Top experts in the field cover key topics such as neutrophilic dermatoses in children; laser surgery for dermatologic conditions in pediatric patients; managing children/families with delusions of infestation/parasitosis; counterfeit medications; and more. Contains 11 relevant, practice-oriented topics including clinical relevance of the cutaneous microbiome in pediatric skin disease; systemic therapy for vascular malformations and the status of genotype-guided management; systemic therapy for pediatric atopic dermatitis; update on biologic therapy for pediatric psoriasis; hormonal treatment of acne in adolescent patients; and more. Provides in-depth clinical reviews on pediatric dermatology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Dermatologic Clinics, guest edited by Drs. Victoria Williams and Carrie Kovarik, will cover a number of important topics in Global Dermatology and Telemedicine. This issue is one of four each year selected by long-time series Consulting Editor, Dr. Bruce Thiers. Topics discussion include, but are not limited to: Patterns of Skin Disease in the Context of a High Prevalence HIV Population in Botswana; Telemedicine and Community Health Projects in Asia; Utilizing Technology for Dermatology Care in Tajikistan: A Health Systems Perspective; Community Outreach Projects to Increase Dermatology Education and Access to Care in Argentina; Challenges and Successes of Dermatology Training Programs in Africa; Developing an Electronic Platform for Global Dermatology Mentorship and Collaboration; Novel Diagnostics for Kaposi Sarcoma and Other Skin Diseases in Resource Poor Settings; Implementing a Locally Made Low-Cost Intervention for Wound and Lymphedema Care in Western Kenya; Challenges of Managing Skin Disease in Migrants and Refugees; Factors Affecting Quality of Life for People Living with Albinism in Botswana; and Integration of Management Strategies for Neglected Tropical Diseases Affecting the Skin

Nail disorders are a specialized group of disorders which are often neglected during post graduate teaching. This book aims to provide a comprehensive review covering the diagnostic and therapeutic aspects of nail disorders. It discusses the basics of nail unit, common conditions like infections, tumors and genetic diseases, diagnostic armamentarium involved in nail diseases like KOH mount, onychoscopy, imaging and surgical management of nail diseases which includes anesthesia of nail unit, nail biopsy and advanced nail procedures including video demonstration of such procedures. This book elaborates on nails in systemic diseases and briefly covers nail cosmetics and nail photography. Key Features Comprehensively reviews nail disorders Includes diagnosis, therapeutic and surgical aspect Discusses Onychoscopy Reviews the importance of nail photography

This book, written by very well-known opinion leaders in the field, covers all aspects of periodic and non -periodic fevers, and related disorders. The expression refers to several different auto-inflammatory diseases, showing similar symptoms-the primary symptom being a recurrent fever for an infectious cause cannot be found. The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications in both pediatric and adult patients. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area. The book is part of Springer's series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. Autoinflammatory diseases are hereditary disorders that are caused by single-gene defects in innate immune regulatory pathways and are characterized by a clinical and biological inflammatory syndrome in which there is limited, if any, evidence of autoimmunity. Periodic and Non-Periodic Fevers will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these disease.

Botulinum Toxins in Dermatology: Cosmetic and Clinical Applications provides a comprehensive and in-depth review of the use of botulinum toxin for aesthetic procedures and medical applications as a stand-alone treatment and as part of combination therapy. Now a mainstay of cosmetic dermatologic practice, the range of available toxins and their varied applications has grown considerably in recent years requiring the practitioner to carefully consider what approach best suits the needs of their patient. This new book, written by international expert authors, provides guidance to help you refine your technique, add new procedures to your practice, and provide optimal results. This book: Offers guidance on best-practice approaches with botulinum toxin, helping create cutting edge, tailored treatment plans for each patient Benefits from a wealth of color images, procedural videos, and expert tips and tricks Takes a region oriented approach, providing guidance on treatment of the; glabella, forehead, periocular and perioral areas, and contouring of the lower face and lower leg and calf, and neck rejuvenation Contains a thorough review of non-cosmetic treatments such as correction of facial asymmetry, and treatment of axillary hyperhidrosis, plus palm, sole, and craniofacial hyperhidrosis Covers exciting new topics, such as future injectables, topical botulinum toxin, and facial contouring including treatment for benign masseter hypertrophy Discusses combination therapy of botulinum toxin with other non-surgical procedures such as hyaluronic acid (HA) or filler substances, light and laser sources, and other energy-based therapies Includes considerations for darker skin types Offer your patients the best care, stay on top of cutting edge techniques, and avoid pitfalls with coverage of practical tips and real cases. Botulinum Toxins in Dermatology: Cosmetic and Clinical Applications provides best-practice guidance on the contemporary use of botulinum toxin in isolation and in combination.

In this issue of Dermatologic Clinics, Guest Editor Kelly M. Cordoro brings considerable expertise to the topic of Pediatric Dermatology. Top experts in the field cover key topics such as Epidermal Nevi in Children, Pigmented Lesions in Children, Normal Skin Findings in Pediatric Patients with Skin of Color, and more. Provides in-depth, clinical reviews on pediatric dermatology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 11 relevant, practice-oriented topics including Presentation of common skin disorders in pediatric patients with skin of color; Tips, Tricks and Pearls to Expertly Treating Common Skin Conditions in Pediatric Patients; Climate and Environmental Health as it Relates to Pediatric Dermatology; and more.

Visible scarring may be a daily reminder of disease long after active acne has subsided. Frequently, it is a cause of distress for the patient and a leading cause for visiting medical professionals. This updated and expanded edition of an acclaimed pioneering text will be invaluable for both general and cosmetic dermatologists, plastic surgeons, and primary care physicians with a specialist interest in the skin as an invaluable guide through the complexities of treatment.

Designed with practicing dermatologists, dermatology trainees, physicians, and scientists interested in photoprotection in mind, this concise and highly illustrated guide provides the latest knowledge of photoprotection in dermatology and cosmetic science. Clinical Guide to Sunscreens and Photoprotection also addresses recent important international and domestic regulatory activity and requirements on the use of novel sun protective chemicals and proper labeling of products to ensure increased consumer awareness. This concisely written, problem-oriented text explores:

Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.

Since skin forms the interface between the human body and the environment, its mechanical properties are important in health and disease. Bioengineering of the Skin: Skin Biomechanics gives a thorough introduction in the biological basis of skin biomechanics. It explains the non-invasive methods that allow measurement of the mechanical properties of the skin focusing on commercially available instruments. Written by internationally leading experts in the field of non-invasive measurement technology of the skin, this volume describes the anatomy, biochemistry, physiology, and pathology of skin biomechanics. It explains in detail how to measure skin mechanic properties and how to use these measurements in the development of drugs and cosmetics.