With a large number of clinical photographs, Making Decisions and Avoiding Complications in Skin Flaps is an atlas intended for the surgeon who already has a grasp of the fundamentals and mechanics of flap repair, but may need additional ideas on selecting an appropriate flap for a given defect. Divided into three sections, the book begins with a section on repairs organized by location on the body. Rather than an exhaustive list of all flaps ever used, the book focuses on the ones the authors have successfully used on a routine basis. The second section contains repairs organized by flap type and the third section contains clinical photographs of suboptimal results with a discussion of what may have gone wrong and what could have been done differently to obtain a better result. The intent of this text is not to showcase results but to present flap options for different defects and anatomic sites. Each example includes a photograph showing the defect and a second showing the repair. When available and/or of educational value, illustrations of the flap or long-term follow-up photos are supplied. Throughout the text, surgical pearls are presented in bold text which can help optimize a particular flap's success rate and/or aesthetic outcome. These pearls have also been compiled into an addendum at the end of the book.

This book focusses on the clinical aspects and management of pediatric skin disorders, especially seen in darker skin types. It includes unique conditions that the authors have encountered in their lifetime with their independent observations and approach to management. Original high-quality images are used to illustrate most dermatoses described in the book enabling a strong visual impression of the discussed diseases. It hopes to provide readers with a blend of evidence and experience based pediatric dermatology. This book aims to be a hands-on manual that can be referred to during a busy practice as it discusses the practical approach to dermatoses. Key Features Focusses on darker skin types. Examines unusual presentations with detailed clinical features. Discusses the ways to differentiate between similar-appearing diseases. Explores approaches to therapy, especially in resource-poor settings. Covers topics with high quality illustrations.

The new edition of Dermatological Signs of Systemic Disease helps you identify a full range of common and rare systemic diseases early on so they can be managed as effectively as possible. Formerly titled Dermatological Signs of Internal Disease, it takes an evidence-based approach to diagnosis and treatment, offering dependable clinical recommendations that enable you to attain definitive diagnoses of internal diseases that manifest on the skin. Allows you to attain definitive diagnoses of internal diseases that manifest on the skin. Uses a consistent, user-friendly format for easy reference. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Covers hot topics such as lupus erythematosus, dermatomyositis, autoinflammatory diseases, eosinophilic and neutrophilic dermatoses, and psoriasis therapies and co-morbidities. Highlights newer therapies and treatment options for most diseases. Includes over 500 full-color illustrations - 200 new to this edition - that provide the best possible representations of diseases as they appear in the clinic. Features more viewpoints from an expanded team of nationally recognized experts in their respective fields.

Marine Cosmeceuticals: Trends and Prospects is a consolidated overview of the marine environment as a productive source of novel cosmeceuticals. It accumulates the latest research in this field from around the globe, highlighting the potential of marine micro and macro flora and fauna as effective agents for the development of novel cosmeceuticals.

• Part I overviews the biological activities of different marine sources and the class of cosmeceutical agents that they may deliver
• Part II describes the chemical properties of marine cosmeceuticals, with special emphasis on chitosan as a cosmeceutical agent
• Part III covers the range of biological properties and bioactive promise that the oceanic environment holds in the field of cosmetology, with a focus on marine fish and sponge derived collagens
• Part IV presents different strategies for enhanced cosmeceutical production via biotechnology
• Part V wraps up with the industrial applications of marine cosmeceuticals, including information on aquatic and marine bioactive antimicrobial peptides

With contributions from Korea, Japan, China, India, Spain, Chile, Malaysia, Canada, Italy, Sri Lanka, and Taiwan, Marine Cosmeceuticals: Trends and Prospects holds great insights for cosmetologists in particular and marine researchers in general. This book offers comprehensive knowledge on novel marine cosmeceutical agents, their biological and chemical properties, and industrial applications.

Topics include: Skin histology, physiology, and pathology, aging; Laser wavelength interface with the skin; Photography for skin's surface; CO2 ablative lasers; YSGG ablative lasers; Erbium ablative lasers; Photodynamic therapy; Treatment of Acne Scarring; Treatment of Skin Texture and Fine Line Etching; Cutaneous facial vascular lesions; Treatment of hyperpigmentation; Treatment of facial hair and body hair; RadioFreqency: Ellman; RadioFrequency: Thermage; Infrared (Titan); SmartLifting; Lasers in Latino skin; Lasers in Black skin; Lasers in Asian skin; Complications in the use of laser skin technologies.

'Dermatological Emergencies' aims to cover aspects of situations and their management when they present in a Dermatology setup. This includes severe drug reactions, bullous disorders, erythroderma, infections, vasculitis and systemic emergencies presenting with skin signs. This book guides the reader to recognize such emergencies, helps to approach the initial phase of management, identifies the investigations, thus leading to a holistic management of the scene. Case scenarios are used in all chapters with logical flow of text, flowcharts, algorithms and representative clinical and laboratory images for better understanding of the readers. Key Features Details all dermatological emergencies Discusses manifestation of these emergencies with unique algorithms and flowcharts Examines case scenarios for first-hand experience Consists of Do's and Don'ts for effective management of cases Uses high quality clinical images for clarity

Our skin changes as we age. It becomes thinner and loses fat, making it less plump and smooth. Clinically, aged skin is characterized by wrinkles, sagging, age spots and dryness. Emphasizing laboratory and clinical research, this book comprehensively describes the molecular mechanisms of human skin-aging and age-related skin diseases. This includes molecular understanding of the development of aging skin and its prevention as well as mechanisms-based clinical rejuvenation. The book also focuses on research to develop mechanisms-based anti-skin-aging products.

In the first volume of this two part issue devoted to Autoimmune Blistering Diseases (AIBD), diagnosis and clinical features of these diseases are covered by an internationally recognized group of authors.? Topics include Pemphigus Vulgaris, Pemphigus Foliaceus, Linear IgA Bullous Disease, and Hair and Nail Loss in AIBD.

Laser has been used in dermatology for over four decades. The concept of selective photothermolysis has transformed our understanding of laser tissue interactions, and there has been an explosive interest in laser treatment for both skin diseases and aesthetic indications over the past decade or more. Asian skin differs from Caucasian skin because of the higher amount of epidermal melanosomes and the higher level of melanin production. Laser- and light-based procedures in darker skin types have a significantly higher risk of complications, including scarring and pigmentary changes as compared with lighter skin types. This book has been highly anticipated as there are not many titles addressing these issues in Asian skin. It includes effective treatment paradigms as well as advice on complications and how to treat them. The book reflects the tremendous progress in the field of laser dermatology. The contributors to this textbook are clinicians with extensive experience in treating Asian skin. The book offers a comprehensive guide to treatment of Asian skin and will be of great value to dermatologists, plastic surgeons, pediatricians and general practitioners, who will benefit from the clinical wisdom that has been distilled from the extensive experience of the editors and contributors.

A comprehensive practical guide to all types of nail surgery, including some cosmetic procedures, this is a master-class for those wishing to perform nail surgery, with clear descriptions of each stage involved and of any complications and how to deal with them.

Tropical Dermatology is reviewed in this issue of Dermatologic Clinics, guest edited by Drs. Scott Norton and Aisha Sethi. Drs. Norton and Sethi have gathered a panel of experts to pen articles on topics including Buruli ulcer, Outbreaks of atypical mycobacterial disease, Streptococcal pyoderma and acute rheumatic fever, Treating MRSA in the tropics, Mosquito-borne hemorrhagic fevers, Dermatologic cases at the National Zoo, Arsenical keratoses, Chagas disease, The AAD's Botswana elective, Gentian violet and similar products used to treat pyodermas, Dermatology in Mali: Leishmaniasis, Albinism in Africa, Female genital mutilation, Use of toxic skin lightening compounds, AIDS and leprosy, and Innate immunity and anti-parasitic vaccine strategies.

Guest Editor Dr. Libby Edwards has gathered a team of expert contributors to pen articles on a challenging area of Dermatology: Vulvar Disease. This issue of Dermatologic Clinics includes articles on Vulvodynia, Pigmented Diseases, Contact Dermatitis, Vulvar Ulcers, Hidradenitis Suppurativum, Desquamative Inflammatory Vaginitis, Histology of the Vulva, Vulvar Pruritus and LSC, Vulvar Erosions, Lichen Planus, Lichen Sclerosus, Vulvar Paget's Disease, and Vulvar Edema.

Over 300 kitchen-tested recipes designed for the psoriasis, eczema, and psoriatic-arthritic patient, plus the latest nutritional facts for everyone

Foreword by Annemarie Colbin, C.H.E.S. and Founder of The Natural Gourmet Institute, New York

Statistics show that more than 100 million people worldwide suffer from the chronic skin disease psoriasis. In his first book, "HEALING PSORIASIS: The Natural Alternative, " Dr. Pagano presented a report of his natural, drug-free treatment regimen that has alleviated, controlled, and even healed psoriasis without the use of steroid creams, tar baths, injections, or ultraviolet treatments.

"Dr. John's Healing Psoriasis Cookbook "is the companion book to "Healing Psoriasis." The cookbook consists of three parts:
Part I - Basic Principles - gives technical data which includes the six principles behind the regimen: 1) Detoxification; 2) Diet and Nutrition; 3) Herb Teas; 4) Spinal Adjustments; 5) External Applications; and 6) Right Thinking
Part II - The Recipes - consists of over 300 original recipes specifically designed for the psoriatic patient
Part III - Eye on Nutrition - is loaded with general nutritional information and advice good for all readers.
There is also a helpful Color Photographic Portfolio of case histories which give undeniable proof of the efficacy of the Pagano regimen.

This issue of Dermatologic Clinics, guest edited by Dr. Ted Rosen, covers the innovative management of dermatologic disorders including Severe Hand Eczema, Pruritus, Furunculosis, Lupus Erythematosus, CTCL, Hidradenitis Suppurativa. Innovative uses of Topical Metronidazole, Topical Calcineurin Inhibitors, Rituximab, TNF-alpha Inhibitors, Thalidomide, Zinc, Dapsone, Spironolactone as an antiandrogen in the treatment of female pattern hair loss, and Therapeutics in Pediatric Dermatology are also reviewed.

Postgraduates studying dermatology can face a lack of appropriate revision aids: reference books are often too exhaustive or out-of-date, while undergraduate and introductory texts lack the necessary detail and depth. This book is specifically designed for postgraduate examinations, and is the perfect accompaniment for the diploma in dermatology.

This book covers all major areas of interest in the rapidly expanding field of in vitro methods for percutaneous absorption studies. Specific areas discussed include diffusion cell design, receptor fluid, preparation of skin, and temperature. The book covers experimental methodology, as well as the underlying principles and fundamentals that help professionals and students gain an understanding of the basis for currently used methodology.

This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barrier may result in damage to the skin or may alter absorption. With contributions from over 40 international experts in the field of skin biology, the book presents the central role of the skin barrier to health and disease reviewing; The skin's anatomy and physiology, with focus on the stratum corneum as a barrier to foreign substances. Dermal absorption, cutaneous metabolism, and epidermal transporters. Altered barriers, racial skin types, aged skin, photoaged skin, cosmetics and skin sensitization. Modern approaches to drug delivery across the skin barrier, including liposomes, microneedle technology, active and passive transdermal delivery. Examples and case studies of chemical toxicity after topical exposures ranging from arsenic, metal working fluids, bromine, jet fuel, sulfur mustard and including the emerging area of nanomaterial penetration. Toxicology of the Skin is essential reading for drug delivery pharmacologist, formulation scientists, dermatologists, toxicologists, molecular biologists, engineers, surgeons, students and anyone interested in skin irritation and skin absorption.

This issue of the Medical Clinics of North America brings the practicing clinician up to date on diagnosis and treatment of dermatologic conditions he may encounter in his daily practice. Guest Edited by preeminent dermatologist, Neil Sadick, this issue covers topics including psoriasis, rosacea, acne, Cutaneous manifestation of systemic diseases, Cutaneous markers of malignancy, diseases of the hair and nails, vasculity, allergic disorders, eczema, urticaria, infectious diseases, skin neoplasms, Cutaneous manifestations of venous disease, and disorders of pigmentation.

Cosmetic Dermatology is reviewed in this issue of Dermatologic Clinics. Dr. Vic Narukar has assembled a panel of experts to pen articles on topics including Cosmeceuticals, Botulinum Toxins, Dermal Fillers, Permanent Fillers, Fillers on the Horizon, Photorejuvenation, Acne Treatments, Non Ablative Fractional Lasers, Ablative and Fractional Ablative Lasers, Tissue Tightening Technologies, Leg Vein Treatments, Medicolegal Issues, Complications, New Research in Aesthetics, and Skin Classification and Aesthetic Procedures in Global Skin.

This issue of Dermatologic Clinics examines Contact Dermatitis. Guest Editor Susan Nedorost has assembled a panel of world-class experts who offer reviews on topics, including Patient education to enhance contact dermatitis evaluation and testing, Recognizing and testing new allergens, Determining relevance of patch tests and avoidance strategies, Hand/face/neck localized pattern: sticky problems-resins, Hand dermatitis: a focus on allergic contact dermatitis to biocides, Run-off pattern or perioral facial dermatitis due to hair and lip products, Clinical patterns of hand and foot dermatitis: emphasis on rubber and chromate allergens, Unusual patterns: medicaments, Clinical patterns of phytodermatitis, Factors associated with textile pattern dermatitis due to contact allergy to dyes, finishes, foams and preservatives, Acute and recurrent vesicular hand dermatitis, Systemic contact dermatitis, Management of occupational dermatitis, and Public health challenges in contact dermatitis.

The field of melanoma biology has experienced a remarkable surge in recent years, owing to progress which has ranged from the most basic laboratory/preclinical discoveries to clinical developments that have begun to transform the management and prognosis for at least certain melanoma patients. Among the key areas that have contributed to this progress are studies relating to signaling and transcriptional pathways that regulate control over differentiation and survival of the melanocyte lineage. The identification of recurring activating mutations in specific signaling factors (B-RAF, N-Ras, c-KIT), amplification of other melanoma oncogenes (MITF, NEDD9), and the crucial recognition that certain of these genomic events occur within melanomas arising with specific clinical features (eg mucosal or acral origin) have led to clear recognition that melanoma is indeed "many different diseases.? While the various subclasses of melanoma may share common features, such as profound invasive and metastatic propensity, it is also likely that sharply focused therapeutic strategies may exploit the functionally critical molecular engines, which distinguish these subclasses. Certain strategies focus upon the immunogenicity and striking clinical opportunities afforded by immune modulation, while others focus more directly on tumor-specific targeting. This issue brings together some of the leaders who have contributed significant insights from basic melanoma biology to progress in the clinic.

Melanoma; Pressure Ulcers; Wound Healing and Biology of the Skin; Local anesthetics-uses and toxicities; Approach to excision and closure of the skin; Unusual Skin Tumors; Dermatologic considerations for the General Surgeon; Suture choice and other skin closure methods; Benign and subcutaneous lesions; Common skin cancers and their precursors; Pilonidal cyst and benign perianal skin conditions

This issue of Dermatologic Clinics examines Dermatologic Epidemiology and Public Health. Guest Editor Robert Dellavalle has assembled a panel of world-class experts who offer reviews on topics including The Neglected Epidemiology and Public Health Problem of Dermatologic Disease, Health Disparities in Dermatology, Survey Research in Dermatology, Guidelines Development in Dermatology, Behavioral Research in Dermatology, Dermatologic Comorbidities, Registry Research in Dermatology, Teledermatology, Occupational Dermatology, Contact Dermatitis, Melanoma, and Interdisciplinary Dermatologic Public Health and Epidemiology Research.

Vitiligo is a disorder having a significant impact in dark-skinned individuals. Along with the historical, cultural, and psychological aspects of the disease the multifactorial pathogenesis of this disorder is discussed in detail with special emphasis on the newer hypotheses proposed in the causation. Descriptions of the clinical aspects of the disease are supplemented with clinical photographs covering the latest therapeutic and surgical treatment options. Nonconventional treatments such as cosmetic camouflage and tattooing are also discussed. Topics of controversy such as the role of diet, patient selection for surgery, and so on, are covered in depth. Key Features Discusses the recent advances in treatment Evidence-based approach Quality of life and psychological aspects covered Nonconventional treatment options included with practical tips on vitiligo surgery Controversial topics covered

Microneedles provide an artificial pathway across the skin barrier for medical and cosmetic applications. This technology has seen a significant increase in popularity over the past years; as an example, the use of multiple small needles mounted on a roller to pierce the skin, prompting it to stimulate collagen production, has undergone a resurgence of interest as an adjunctive procedure for a number of skin disorders. This monograph draws together what is known about how to integrate microneedle technology into clinical dermatologic practice.