Authored by experts in the field, this brand-new reference presents a systematic approach to which flap or graft to use in which clinical situation and how to cut and move the skin. More than 350 full-color photographs and line drawings offer you step-by-step guidance. And, a DVD containing high-quality video clips demonstrates reconstructive procedures, including cutting, positioning, and suturing of flaps and grafts. Describes which flap or graft to choose in specific clinical situations, how to execute each repair (with a multitude of images and diagrams), and how to minimize the risks as well as manage potential complications. Provides algorithms to assist with flap and graft choices, as well as hundreds of superb full-color illustrations throughout. Includes an all-new chapter on Surgical Complications and Scar Revisions. Includes access to high-quality videos showing exactly how the flap/graft is incised, moved, and sutured. New videos include the Rhomboid Transposition Flap for Defect on the Lower Lid, the Island Pedicle Flap with Canthal Suspension, and the Primary Lid Repair with Diagonal Tarsal Suture Sine Marginal Sutures. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods, Fifth Edition supplies new chapters on topics currently impacting the field including cutaneous metabolism, skin contamination, exposure to protein allergens, in vitro absorption methodology and the percutaneous absorption of chemical mixtures. Complete with studies on the role of the skin as a key portal of entry for chemicals into the body, this book serves as a detailed reference source for recent advances in the field, as well as an experimental guide for laboratory personnel. Key Features: Details in vivo and in vitro methods for measuring absorption, dermal decontamination, mechanisms of transdermal delivery, and the relationship of transepidermal water loss to percutaneous absorption Considers a range of mathematical models, the safety evaluation of cosmetic ingredients, the absorption of hair dyes, nanoparticles for drug delivery, and other novel methods of drug delivery Discusses topics including skin metabolism, the skin reservoir, and the effects of desquamation on absorption

Dressings for Advanced Wound Care focuses on helping the reader better understand advanced wound care and relevant technologies. It explains how different types of wounds may require different environments to heal and how dressings can help in creating the right environment. It gives an overview of the various dressing technologies that are available to help manage wounds that are difficult to heal. Finally, this book highlights the current trends that may be directing the future of the advanced wound dressing sector. FEATURES: Relates technologies with commercially available end-products, giving the reader a more specific overview of the advanced wound dressing sector Provides a realistic overview of the process of developing an advanced wound care dressing Summarises recent clinical evidence on advanced wound dressings Explains how dressings differ and what works best for which wound type Examines clinical evidence on technologies and on-market products Describes the requirements for launching a new advanced wound dressing This book is aimed at medical clinicians and professionals in the fields of biomedical engineering, textile science, and materials engineering.

This book provides a current experience in the diagnostic techniques and treatment approaches available for unusual cutaneous lymphomas. It features concise case-based chapters with a particular emphasis on instances of mature T-cell and NK-cell neoplasms, mature B-cell neoplasms, immature hematopoietic malignancies, and other lymphoproliferative disorders. Clinically-oriented cases emphasize the importance of physical examination along with modern tests of laboratory diagnostics and clinico-pathological correlations. Cutaneous Lymphomas: Unusual Cases 3 presents a range of difficult and rare cases, which would be uncommon even to the specialists in this field. Therefore, it is a vital reference source for dermatologists, dermatophatologists, cutaneous oncologists, hematooncologists, pathologists, oncologists, and other medical professionals who treat these patients.

Lernen Sie von den Fachleuten und verbessern Sie Ihre diagnostische Genauigkeit, indem Sie mit diesem gut bebilderten Leitfaden uber die Dermatopathologie infektioeser und parasitarer Dermatosen die UEbereinstimmung klinischer Studien mit histopathologischen Untersuchungen uberprufen, inbegriffen tropische Hautkrankheiten Dieses neue Buch: - betont geradlinige muster-basierte Ansatze fur die dermatologischen Diagnose. - pruft die Passung klinischer Funktionsstoerungen mit histopathologischen Verfahren zur Gewinnung eines vollstandigen diagnostischen Bildes. - enthalt mehr als 250 herausragende Bilder mit Kommentaren zur Unterstutzung einer genauen Diagnose. - ist ein pragnanter Leitfaden mit diagnostischen Hinweisen. - stammt von weltweit anerkannten Autoren. Dieses Buch ist das ideale Referenzwerk zur Vorbereitung von Abschlussprufungen und zur Anleitung von Klinikarzten und Pathologen in der dermatopathologischen Praxis.

While science and technology have been moving at speed in the last decade and major investments have been placed in Artificial Intelligence, blockchain technology, 3D printing, and gene editing, medical practice, including cutaneous medicine (otherwise known as Dermatology), is only just starting to follow these technological advances. This book is a timely intellectual investment for cutaneous medicine, addressing these particularly needed areas. It is written for medical educators, dermatology residents, practicing dermatologists, and medical researchers in the area of skin diseases, to alert them all to medical advances and up-and-coming technology and in the hope, it will inspire further novel methodology for the future of cutaneous medicine, in diagnosis and therapy.

This second volume in an exciting and detailed series on contact allergens provides monographs of all 181 fragrances and 79 essential oils which have caused contact allergy / allergic contact dermatitis, including the indicators for fragrance allergy (fragrance mixes I and II and Myroxylon pereirae resin [Balsam of Peru]) and non-fragrance allergens in botanical products used in the perfume industry. The monographs present: Identification section; Contact allergy (general population, patients with dermatitis, case reports and case series); Cross-reactions; Patch test sensitization; Presence in products and chemical analyses; Other side effects (irritant contact dermatitis, photosensitivity, immediate-type reactions, systemic side effects) and more. Key Features: Presents monographs of all known fragrance chemicals and essential oils which have caused contact allergy / allergic contact dermatitis Provides a full literature review of relevant topics of allergenic fragrances and essential oils Identifies INCI and IUPAC names, synonyms, CAS and EC numbers, structural formulas, RIFM and Merck Index monographs, SCCS opinions, IFRA and EU restrictions and advises on patch testing Presents an alphabetical list of all synonyms indicating their INCI names Covers an extensive amount of information to benefit dermatologists, allergists, and non-medical professionals involved with the research, development and marketing of fragrances and essential oils

Dressings for Advanced Wound Care focuses on helping the reader better understand advanced wound care and relevant technologies. It explains how different types of wounds may require different environments to heal and how dressings can help in creating the right environment. It gives an overview of the various dressing technologies that are available to help manage wounds that are difficult to heal. Finally, this book highlights the current trends that may be directing the future of the advanced wound dressing sector. FEATURES: Relates technologies with commercially available end-products, giving the reader a more specific overview of the advanced wound dressing sector Provides a realistic overview of the process of developing an advanced wound care dressing Summarises recent clinical evidence on advanced wound dressings Explains how dressings differ and what works best for which wound type Examines clinical evidence on technologies and on-market products Describes the requirements for launching a new advanced wound dressing This book is aimed at medical clinicians and professionals in the fields of biomedical engineering, textile science, and materials engineering.

Psoriasis is a life-long chronic autoimmune disease characterized by thick scaly skin lesions and often associated with severe arthritis. In psoriasis, lesions skin cells, keratinocytes, grow too quickly, resulting in thick, white, silvery or red patches on skin. Normal skin cells grow gradually and flake off about every four weeks, but psoriasis causes new skin cells to move rapidly to the surface of the skin in days rather than weeks. Psoriasis symptoms often appear on the elbows, scalp, feet, knees, hands, or lower back, or as flaking or patches on the skin. It is most common in adults, but teenagers and children can also suffer from psoriasis. Psoriasis is not only a skin condition; it is a chronic disease of the immune system. Chronic psoriasis is associated with other health conditions such as psoriatic arthritis, several inflammatory disorders, type 2 diabetes, and cardiovascular disease. This book provides extensive coverage of psoriasis and psoriatic arthritis. It features information on epidemiology and etiology of psoriasis, pathogenesis, genetics of psoriasis, clinical manifestations, and treatment options using cutting-edge drugs including adalimumab and tofacitinib. Natural phytochemicals and nutraceuticals have demonstrated efficacy in ameliorating psoriasis. The book dedicates comprehensive coverage of nutraceutical therapeutic options including antioxidants, bioactive peptides, carotenoids, alpha lipoic acid, curcumin, and whey protein. These inexpensive natural therapeutics are not associated with any known adverse side effects.

This new volume provides exhaustive knowledge on a wide range of natural products and holistic concepts that have provided promising in the treatment of leishmaniasis. Including the major natural therapies as well as traditional formulations, over 300 medicinal plants and 150 isolated compounds that are reported to have beneficial results in the treatment of the disease are explored in this comprehensive work. This book also acts as an important resource on various anti-inflammatory plants used to treat various inflammatory conditions of the disease.

New developments in the field of the commonly used photodiagnostic and phototherapeutic methods help to continuously improve the results in the daily practise. Edited by internationally renowned experts, the new edition offers up-to-date, comprehensive and clinically relevant information on every aspect of photodiagnostic and phototherapy. The book is structured in following parts: Photochemotherapy in daily practice, special phototherapeutic modalities and photoprotection in daily practice. Due to the detailed structure this new edition is even more reader-friendly and has a strong focus on clinical aspects. It includes: Guidelines for the treatment selections of specific diseases, practical guidelines for phototherapy with information about basic principles of photobiology, standardized test protocols for photodermatoses and diagnosis for skin tumors.

This textbook presents the current (and near-future) state of affairs of molecular testing as it pertains to the dermatology patient. It focuses on practical applications of molecular diagnostics over a cross-section of dermatologic disease, including melanoma, lymphoma, soft tissue tumors, genodermatoses, and infectious disease. It includes practical advice to those ordering molecular tests as well as to those considering performing such tests, providing a potential template for a comprehensive dermatologic molecular diagnostics test menu. Pitfalls of interpretation and algorithmic approaches to testing are included. The textbook is directed towards all readers - clinicians, pathologists, laboratorians, and other inquisitive minds - independent of their level of molecular expertise, to provoke thought or perhaps even change practice. The context for the book is the rapid evolution of the field of molecular diagnostics, which is becoming more pervasive in all disciplines of medicine, including dermatology. This is indeed an exciting time in dermatology. Molecular testing is now incorporated into all aspects of patient management, including diagnostics (identifying and classifying disease), prognostics (predicting disease course), and theranostics (predicting response to therapy). For example, molecular tests are now used to detect germline mutations that result in genodermatoses, somatic genetic events that characterize tumors such as melanoma and sarcomas, and genetic material of otherwise undetectable infectious organisms. For melanoma and lymphoma, testing can potentially predict tumor behavior and modify patient staging. Regarding theranostics, molecular tests that identify specific mutations in proto- oncogenes, such as BRAF and others, are now used to predict which patients will respond to designer targeted therapies. Molecular theranostics has revolutionized the entire treatment paradigm for patients with advanced melanoma, repla

Practical Guide to Botulinum Toxin Injections is the perfect solution for trainees and novice injectors looking for technical guidance performing chemodenervation procedures using botulinum toxin. This high-yield pocket book provides a visual roadmap for procedural targets with illustrations of each muscle and labeled injection sites and includes dosing recommendations for all clinically-available toxins.The manual walks readers through a brief introduction to toxin use before diving into applications muscle by muscle. Each body region gives a closer look at the individual muscles involved, detailing muscle action, injection localization, recommended dosing and injection sites, and pearls and pitfalls where relevant. Later sections address other clinical applications including cervical dystonia, migraine, blepharospasm, hyperhidrosis, and special clinical syndromes such as writer's cramp. Complete with original illustrations detailing anatomy and suggested injection localization for targeted muscles, this "one-stop-shop" reference will appeal to anyone in physical medicine and rehabilitation, neurology, dermatology, pain management, and other fields seeking to acquire or reinforce skills. Key Features: Over 135 detailed anatomic illustrations with suggested injection points Dosing recommendations for 95 muscles throughout the upper and lower limbs and axial muscle groups Coverage of clinical applications and syndromes to help providers recognize common patterns of muscle involvement Purchase includes digital access for use on most mobile devices or computers

This issue of Dermatologic Clinics, guest edited by Drs. Victoria Williams and Carrie Kovarik, will cover a number of important topics in Global Dermatology and Telemedicine. This issue is one of four each year selected by long-time series Consulting Editor, Dr. Bruce Thiers. Topics discussion include, but are not limited to: Patterns of Skin Disease in the Context of a High Prevalence HIV Population in Botswana; Telemedicine and Community Health Projects in Asia; Utilizing Technology for Dermatology Care in Tajikistan: A Health Systems Perspective; Community Outreach Projects to Increase Dermatology Education and Access to Care in Argentina; Challenges and Successes of Dermatology Training Programs in Africa; Developing an Electronic Platform for Global Dermatology Mentorship and Collaboration; Novel Diagnostics for Kaposi Sarcoma and Other Skin Diseases in Resource Poor Settings; Implementing a Locally Made Low-Cost Intervention for Wound and Lymphedema Care in Western Kenya; Challenges of Managing Skin Disease in Migrants and Refugees; Factors Affecting Quality of Life for People Living with Albinism in Botswana; and Integration of Management Strategies for Neglected Tropical Diseases Affecting the Skin

This updated edition provides research scientists, microbiologists, process engineers, and plant managers with an authoritative resource on basic microbiology, manufacturing hygiene, and product preservation. It offers a contemporary global perspective on the dynamics affecting the industry, including concerns about preservatives, natural ingredients, small manufacturing, resistant microbes, and susceptible populations. Professional researchers in the cosmetic as well as the pharmaceutical industry will find this an indispensable textbook for in-house training that improves the delivery of information essential to the development and manufacturing of safe high-quality products

This updated edition provides research scientists, microbiologists, process engineers, and plant managers with an authoritative resource on basic microbiology, manufacturing hygiene, and product preservation. It offers a contemporary global perspective on the dynamics affecting the industry, including concerns about preservatives, natural ingredients, small manufacturing, resistant microbes, and susceptible populations. Professional researchers in the cosmetic as well as the pharmaceutical industry will find this an indispensable textbook for in-house training that improves the delivery of information essential to the development and manufacturing of safe high-quality products

Atopic dermatitis (eczema) is one of the most common and most challenging skin conditions, for patients and practitioners alike. Uniquely organized by intrinsic and extrinsic etiologies, Atopic Dermatitis: Inside Out or Outside In? examines a myriad of causes that start from both the inside of the body and from the external environment, offering physicians practical ways to design treatments that specifically address these causes. Drs. Lawrence S. Chan and Vivian Y. Shi, along with a team of expert contributing authors, examine the etiology of this complex disorder and provide targeted, comprehensive solutions and the most useful therapeutic plans based on pathophysiology, including evidence-based integrative management. Analyzes the pathophysiology of atopic dermatitis from two distinct fronts: inside out and outside in-an approach that is unique in the field. Begins with an overview of the disease, then delves into both internal and external pathogenic factors, followed by the Clinician's Corner, which offers practical recommendations for treatment. Organizes therapeutic discussions by corresponding pathophysiology rather than a one-size-fits-all approach. Covers recently FDA-approved and emerging medications, as well as atopic comorbidities. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Despite being a relatively straightforward clinical diagnosis, recognition of hidradenitis suppurativa (HS) is highly variable, and clinical management is challenging and complex. Written by the world's leading experts in HS, A Comprehensive Guide to Hidradenitis Suppurativa brings together up-to-date scientific evidence on the diagnosis, patho-mechanisms, comorbidities, and multi-faceted medical and surgical interventions for this debilitating condition-in one convenient reference. Covers every aspect of this complex skin disorder: etiology, pathophysiology, epidemiology, medical, alternative therapies, a range of surgical options, laser treatments, and comorbidities. Discusses specific patient populations such as children, women of childbearing potential, and pregnant and breastfeeding women. Because HS has higher prevalence in people of skin of color, this patient population is well-documented in the text. Offers insights into multi-disciplinary care, patient support and education, patients at risk for rapid disease progression, and clinical and translational research. Features procedural videos covering laser therapies, de-roofing procedures, excision techniques, cryoinsufflation techniques, and special wound care material selection and techniques. Includes promising future drugs and therapies that are under investigation. Identifies evidence gaps that provide a springboard to the future innovations in HS care to come. Edited and authored by global experts who have helped co-author U.S., Canadian, and European guidelines on HS. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Assembling, reviewing, and synthesizing state-of-the-art information on translational research and therapies of melanoma into one convenient source, Melanoma: Translational Research and Emerging Therapies provides clinicians and researchers the necessary context and perspective to intergrate and effectively deploy cutting-edge therapies into daily practice. This source: synthesizes the scientific principles, clinical trial results, and clinical implications of emerging and translational melanoma therapies covers the entire range of translational research and therapies, including pathogenesis, progression pathways, immunotherapy, gene therapy, adjuvant therapy, surgical staging, and metastatic disease provides context and perspective to enable the clinician to select and use new therapies effectively and knowledgeably

From anti-aging creams to make-up, surfactants play a key role as delivery systems for skin care and decorative cosmetic products. Surfactants in Personal Care Products and Decorative Cosmetics, Third Edition presents a scientific basis in surfactant science and recent advances in the industry necessary for understanding, formulating, and testing surfactant-based cosmetics and cosmeceuticals. Presenting a new perspective from the previous edition, this book details the function of emulsions, microemulsions, micelles, and nanostructures in the formulation of personal care products and decorative cosmetics and examines their ability to deliver specific benefits to the skin. This edition begins by describing new research into skin structure and cellular processes. Then it presents the latest methods and techniques for substantiating claims and assessing the effectiveness of moisturizers, anti-aging treatments, and sunscreens. Subsequent chapters focus on surfactant solution properties, surfactant emulsions, nanotechnology, cleanser/conditioner systems, and pigment dispersions. Following a detailed examination on the role of surfactants in finished pigmented products, this edition also discusses optimal formulation strategies and surfactant raw materials for enhancing pigmented products. The third edition of Surfactants in Personal Care Products and Decorative Cosmetics, Third Edition helps formulators identify and overcome the challenges involved in developing new applications and enhancing the benefits of cosmetic and cosmeceutical products.

This issue of Dermatologic Clinics, guest edited by Dr. Christen M. Mowad, will cover a number of important topics related to Allergic Contact Dermatitis. This issue is one of four each year selected by longtime series Consulting Editor, Dr. Bruce Thiers. Topics discussion include, but are not limited to: Occupational Contact Dermatitis; Considerations When Performing Pediatric Allergic Contact Dermatitis; The Importance of Education When Patch Testing; The Concern Over Implants and Metal Patch Testing; Atopic Dermatitis and Allergic Contact Dermatitis; Allergen of the Year; Allergic Contact Dermatitis in Healthy and Chronically Inflamed Skin; Systemic Contact Dermatitis; Fragrance Allergy; and Plant Allergic Contact Dermatitis, among others.

This book intends to investigate the broad spectrum of genetic changes in immunological processes involved in cutaneous diseases. One of the main goals of immunogenetic studies is finding susceptibility genes for complex diseases. This can provide an insight into the pathogenesis of the condition in a way that is not easily achievable through other kinds of studies. Thus they are a rational initial step for generating hypotheses about disease pathogenesis. This may especially benefit dermatology, a field notorious for having too many diseases with unknown etiologies. Immunogenetic investigations have made targeted treatment strategies possible for diseases such as psoriasis and pemphigus. Even though these strategies have revolutionized the management of chronic dermatological conditions such as psoriasis, still there are a lot of unanswered questions. For instance, psoriasis patients respond very differently to each of the commercially available biological agents. This diversity could be partially explained by the differences in the sets of genes responsible for disease induction in each individual. Thus whole genome sequencing strategies, if feasible at individual levels, might help in tailoring these targeted treatments based on specific genetic backgrounds. Our intention in preparing this book was to explore the broad spectrum of the genetic aspects of immunological processes involved in cutaneous diseases. We have tried to cover most areas of dermatology where enough studies were available to gather a chapter. Still, there is a substantial lack of knowledge on the immunogenetics of many dermatological conditions. We hope that this book would encourage the investigators to fill these gaps of knowledge.

This book is devoted exclusively to differential diagnosis in pediatric dermatology. It covers the full range of relevant conditions: inherited skin disorders; nevi; viral, bacterial, fungal, and parasitic infections; acne; allergic diseases; autoimmune skin disorders; connective tissue diseases; tumors; and miscellaneous conditions. Each comparison addresses the differential diagnosis between two (or occasionally three or four) dermatological conditions, containing between two and six images and a short text emphasizing the clinical differences between the diseases in question. At the end of each chapter, a summary highlights one or two characteristics essential for the differential diagnosis. The author is an expert who, since 1982, has been responsible for a column devoted to the differential diagnosis of pediatric dermatology in the European Journal of Pediatric Dermatology. The volume will represent an ideal tool for pediatric dermatologists, pediatricians, and GPs, and will help them in the diagnostic process.

This issue of Dermatologic Clinics, guest edited by Drs. Lauren Meshkov Bonati and Jared Jagdeo, is devoted to Lesbian, Gay, Bisexual, and Transgender Dermatology. Articles in this timely issue include: Historical Perspective on the Dermatologic Care of Sexual and Gender Minority Populations; Healthcare Inequities and Resultant Morbidity in the Sexual and Gender Minority Population; Editorial: Transgender Patients' Experiences in Healthcare; Medical Dermatology and Multidisciplinary Care for Lesbian, Gay, Bisexual, Transgender, and Questioning Patients; Skin Cancer and Risk Factors in the Lesbian, Gay, Bisexual, Transgender, and Questioning Population; Acne and the Lesbian, Gay, Bisexual, and Transgender Teenager; Penile, Scrotal, and Anal Dermatitides in Male Sexual and Gender Minority Patients; What Every Dermatologist Should Know About PrE P; Where Do We Stand Now? A Survey of Physicians Involved in Gender Affirming Care; Androgenetic Alopecia in Gender Minority Patients; Minimally Invasive Procedures for Gender Affirmation; Surgical Facial Aesthetics for Gender Affirmation; Ways to Improve Sexual and Gender Minority Care in the Office and Institution; and How to Start a Resident Clinic for Lesbian, Gay, Bisexual, and Transgender Patients.

In her informative new book, WHAT'S STRESSING YOUR FACE, the author outlines every possible reason for a person to develop a problem that appears symptomatically on the face. The book discusses a number of stress-related conditions, including rashes, psoriasis, rosacea and eczema, plus aging-related issues, hair problems and nerve-related troubles. There are, also, individual treatment chapters, from simple massages to psychotherapy, that explore the most effective healing solutions and how each type works. Also included are innovative treatments, such as light-emitting diode treatments for worry wrinkles and electrical stimulation, along with over-the-counter products and non-invasive procedures. Throughout, there are case histories from the doctor's practice that richly illustrate the conditions. Anyone who has a troubling facial malady would do well to take advantage of the detailed healing techniques this knowledgeable book provides and put themselves on the path to recovery.