Nail disorders are a specialized group of disorders which are often neglected during post graduate teaching. This book aims to provide a comprehensive review covering the diagnostic and therapeutic aspects of nail disorders. It discusses the basics of nail unit, common conditions like infections, tumors and genetic diseases, diagnostic armamentarium involved in nail diseases like KOH mount, onychoscopy, imaging and surgical management of nail diseases which includes anesthesia of nail unit, nail biopsy and advanced nail procedures including video demonstration of such procedures. This book elaborates on nails in systemic diseases and briefly covers nail cosmetics and nail photography. Key Features Comprehensively reviews nail disorders Includes diagnosis, therapeutic and surgical aspect Discusses Onychoscopy Reviews the importance of nail photography

Approaches skin disorders morphologically. Emphasises on key diagnostic clinical points. Includes different presentations of common skin conditions. Emphasises on common clinical conditions presenting in a routine OPD. Includes good quality clinical photographs.

Highly visual and uniquely convenient, Pediatric Dermatology DDX Deck, 3rd Edition, Is the quickest, easiest way to compare and contrast 164 of the most common pediatric dermatologic diagnoses. Each card in this swatch-style deck includes full-color images and information about a particular diagnosis, as well as cross-references (DDx refs) to other potential diagnoses. Designed with the busy practitioner in mind, it's the perfect pocket-sized reference for front-line pediatric dermatologic diagnosis. Compare potential diagnoses visually, side by side, with more than 600 full-color clinical images - no more flipping back and forth between different diagnostic possibilities. Concise descriptions of clinical features and treatment for each condition, as well as clear cross-references to other possible diagnoses. New topics include mycoplasma mucositis, acute eruptive generalized pustulosis (AGEP), periarteritis nodosa, mosaic hypopigmentation, Waardenburg's syndrome, congenital atrichia with papules, and more. New coverage of biologics throughout, plus new content on erythema toxicum. Arranged according to skin appearance, helping you find the most relevant condition more quickly. An ideal, pocket-sized guide to diagnosis of children of all ages, including newborns.

Phototherapy, or the usage of light to treat diseases, is an important modality in a physician's therapeutic armamentarium. It is effective for a number of common skin conditions like atopic dermatitis, psoriasis and vitiligo. The accurate diagnosis of a photodermatosis or light-related skin disorder relies on a good clinical history and physical examination, supported by diagnostic investigations such as phototesting.Phototherapy and Photodiagnostic Methods for the Practitioner is the first published set of practical guidelines for Asian skin, drawing upon our cumulative clinical experience with phototherapy for various conditions at the National Skin Centre in Singapore, amalgamated with up-to-date evidence from the scientific literature. It is designed to serve as a concise and comprehensive reference manual for dermatologists, as well as clinicians, medical physicists and nurses with an interest in photodiagnostic investigations and phototherapy for the evaluation and treatment of skin disorders.

Despite being a relatively straightforward clinical diagnosis, recognition of hidradenitis suppurativa (HS) is highly variable, and clinical management is challenging and complex. Written by the world's leading experts in HS, A Comprehensive Guide to Hidradenitis Suppurativa brings together up-to-date scientific evidence on the diagnosis, patho-mechanisms, comorbidities, and multi-faceted medical and surgical interventions for this debilitating condition-in one convenient reference. Covers every aspect of this complex skin disorder: etiology, pathophysiology, epidemiology, medical, alternative therapies, a range of surgical options, laser treatments, and comorbidities. Discusses specific patient populations such as children, women of childbearing potential, and pregnant and breastfeeding women. Because HS has higher prevalence in people of skin of color, this patient population is well-documented in the text. Offers insights into multi-disciplinary care, patient support and education, patients at risk for rapid disease progression, and clinical and translational research. Features procedural videos covering laser therapies, de-roofing procedures, excision techniques, cryoinsufflation techniques, and special wound care material selection and techniques. Includes promising future drugs and therapies that are under investigation. Identifies evidence gaps that provide a springboard to the future innovations in HS care to come. Edited and authored by global experts who have helped co-author U.S., Canadian, and European guidelines on HS. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Assembling, reviewing, and synthesizing state-of-the-art information on translational research and therapies of melanoma into one convenient source, Melanoma: Translational Research and Emerging Therapies provides clinicians and researchers the necessary context and perspective to intergrate and effectively deploy cutting-edge therapies into daily practice. This source: synthesizes the scientific principles, clinical trial results, and clinical implications of emerging and translational melanoma therapies covers the entire range of translational research and therapies, including pathogenesis, progression pathways, immunotherapy, gene therapy, adjuvant therapy, surgical staging, and metastatic disease provides context and perspective to enable the clinician to select and use new therapies effectively and knowledgeably

From anti-aging creams to make-up, surfactants play a key role as delivery systems for skin care and decorative cosmetic products. Surfactants in Personal Care Products and Decorative Cosmetics, Third Edition presents a scientific basis in surfactant science and recent advances in the industry necessary for understanding, formulating, and testing surfactant-based cosmetics and cosmeceuticals. Presenting a new perspective from the previous edition, this book details the function of emulsions, microemulsions, micelles, and nanostructures in the formulation of personal care products and decorative cosmetics and examines their ability to deliver specific benefits to the skin. This edition begins by describing new research into skin structure and cellular processes. Then it presents the latest methods and techniques for substantiating claims and assessing the effectiveness of moisturizers, anti-aging treatments, and sunscreens. Subsequent chapters focus on surfactant solution properties, surfactant emulsions, nanotechnology, cleanser/conditioner systems, and pigment dispersions. Following a detailed examination on the role of surfactants in finished pigmented products, this edition also discusses optimal formulation strategies and surfactant raw materials for enhancing pigmented products. The third edition of Surfactants in Personal Care Products and Decorative Cosmetics, Third Edition helps formulators identify and overcome the challenges involved in developing new applications and enhancing the benefits of cosmetic and cosmeceutical products.

This book is devoted exclusively to differential diagnosis in pediatric dermatology. It covers the full range of relevant conditions: inherited skin disorders; nevi; viral, bacterial, fungal, and parasitic infections; acne; allergic diseases; autoimmune skin disorders; connective tissue diseases; tumors; and miscellaneous conditions. Each comparison addresses the differential diagnosis between two (or occasionally three or four) dermatological conditions, containing between two and six images and a short text emphasizing the clinical differences between the diseases in question. At the end of each chapter, a summary highlights one or two characteristics essential for the differential diagnosis. The author is an expert who, since 1982, has been responsible for a column devoted to the differential diagnosis of pediatric dermatology in the European Journal of Pediatric Dermatology. The volume will represent an ideal tool for pediatric dermatologists, pediatricians, and GPs, and will help them in the diagnostic process.

Laser has been used in dermatology for over four decades. The concept of selective photothermolysis has transformed our understanding of laser tissue interactions, and there has been an explosive interest in laser treatment for both skin diseases and aesthetic indications over the past decade or more. Asian skin differs from Caucasian skin because of the higher amount of epidermal melanosomes and the higher level of melanin production. Laser- and light-based procedures in darker skin types have a significantly higher risk of complications, including scarring and pigmentary changes as compared with lighter skin types. This book has been highly anticipated as there are not many titles addressing these issues in Asian skin. It includes effective treatment paradigms as well as advice on complications and how to treat them. The book reflects the tremendous progress in the field of laser dermatology. The contributors to this textbook are clinicians with extensive experience in treating Asian skin. The book offers a comprehensive guide to treatment of Asian skin and will be of great value to dermatologists, plastic surgeons, pediatricians and general practitioners, who will benefit from the clinical wisdom that has been distilled from the extensive experience of the editors and contributors.

This issue of Dermatologic Clinics, guest edited by Dr. Christen M. Mowad, will cover a number of important topics related to Allergic Contact Dermatitis. This issue is one of four each year selected by longtime series Consulting Editor, Dr. Bruce Thiers. Topics discussion include, but are not limited to: Occupational Contact Dermatitis; Considerations When Performing Pediatric Allergic Contact Dermatitis; The Importance of Education When Patch Testing; The Concern Over Implants and Metal Patch Testing; Atopic Dermatitis and Allergic Contact Dermatitis; Allergen of the Year; Allergic Contact Dermatitis in Healthy and Chronically Inflamed Skin; Systemic Contact Dermatitis; Fragrance Allergy; and Plant Allergic Contact Dermatitis, among others.

Doctors and the general public are increasingly recognising diseases of the vulva and vagina as a cause of sexual dysfunction, morbidity and death, yet the wide but sometimes rare range of conditions involving this area are poorly represented in most textbooks of pathology. As the first volume in the Essentials of Diagnostic Gynecological Pathology series sponsored by the British Association of Gynecological Pathologists, Pathology of the Vulva and Vagina is one of the very few dealing wholly with this subject. Pathology of the Vulva and Vagina introduces the topic with a stylishly illustrated description of the embryology and development which is fundamental to understanding the pathogenesis and symptomatology. Subsequent chapters cover infections and non- infectious dermatoses, specifying those that can predispose to cancer. The precancerous conditions of vulval intraepithelial neoplasia, melanocytic proliferations and extra-mammary Paget's disease are integrated respectively with accounts of human papilloma virus, malignant melanoma and recent awareness of ano- genital mammary-like glands. Advances in the recognition of potentially confusing benign conditions, prognosis and staging update the pathology of squamous and adenocarcinoma in these organs. The difficulties of sentinel node biopsy are explored and a comprehensive chapter clearly highlights the difficult differential diagnosis of mesenchymal lesions. As most histopathology departments receive many gynecological specimens, Pathology of the Vulva and Vagina has been written to be useful diagnostically to general as well as specialist gynecological histopathologists and pathologists in training. Gynecologists, oncologists, dermatologists, genitourinary physicians and cancer nurse specialists will find expert insights here that will help in treatment and counselling of their patients.

This issue of Dermatologic Clinics, guest edited by Drs. Lauren Meshkov Bonati and Jared Jagdeo, is devoted to Lesbian, Gay, Bisexual, and Transgender Dermatology. Articles in this timely issue include: Historical Perspective on the Dermatologic Care of Sexual and Gender Minority Populations; Healthcare Inequities and Resultant Morbidity in the Sexual and Gender Minority Population; Editorial: Transgender Patients' Experiences in Healthcare; Medical Dermatology and Multidisciplinary Care for Lesbian, Gay, Bisexual, Transgender, and Questioning Patients; Skin Cancer and Risk Factors in the Lesbian, Gay, Bisexual, Transgender, and Questioning Population; Acne and the Lesbian, Gay, Bisexual, and Transgender Teenager; Penile, Scrotal, and Anal Dermatitides in Male Sexual and Gender Minority Patients; What Every Dermatologist Should Know About PrE P; Where Do We Stand Now? A Survey of Physicians Involved in Gender Affirming Care; Androgenetic Alopecia in Gender Minority Patients; Minimally Invasive Procedures for Gender Affirmation; Surgical Facial Aesthetics for Gender Affirmation; Ways to Improve Sexual and Gender Minority Care in the Office and Institution; and How to Start a Resident Clinic for Lesbian, Gay, Bisexual, and Transgender Patients.

This book intends to investigate the broad spectrum of genetic changes in immunological processes involved in cutaneous diseases. One of the main goals of immunogenetic studies is finding susceptibility genes for complex diseases. This can provide an insight into the pathogenesis of the condition in a way that is not easily achievable through other kinds of studies. Thus they are a rational initial step for generating hypotheses about disease pathogenesis. This may especially benefit dermatology, a field notorious for having too many diseases with unknown etiologies. Immunogenetic investigations have made targeted treatment strategies possible for diseases such as psoriasis and pemphigus. Even though these strategies have revolutionized the management of chronic dermatological conditions such as psoriasis, still there are a lot of unanswered questions. For instance, psoriasis patients respond very differently to each of the commercially available biological agents. This diversity could be partially explained by the differences in the sets of genes responsible for disease induction in each individual. Thus whole genome sequencing strategies, if feasible at individual levels, might help in tailoring these targeted treatments based on specific genetic backgrounds. Our intention in preparing this book was to explore the broad spectrum of the genetic aspects of immunological processes involved in cutaneous diseases. We have tried to cover most areas of dermatology where enough studies were available to gather a chapter. Still, there is a substantial lack of knowledge on the immunogenetics of many dermatological conditions. We hope that this book would encourage the investigators to fill these gaps of knowledge.

Humanhairisananocompositebiological?ber. Maintainingthehealth,feel,shine, color,softness,andoverallaestheticsofthehairishighlydesired. Haircarepr- ucts such as shampoos and conditioners, along with damaging processes such as chemical dyeing and permanent wave treatments, affect the maintenance and groomingprocessandareimportanttostudybecausetheyaltermanyhairprop- ties. Nanoscalecharacterizationofthecellularstructure,mechanicalproperties,and morphological, frictional,andadhesive properties(tribologicalproperties)ofhair areessentialtoevaluateanddevelopbettercosmeticproductsandtoadvancethe understandingofbiologicalandcosmeticscience. Theatomic/frictionforcemic- scope(AFM/FFM)andnanoindenterhavebecomeimportanttoolsforstudyingthe micro/nanoscalepropertiesofhumanhair. Inthisbook,wepresentacomprehensive review of structural, nanomechanical, and nanotribological properties of various hairandskinasafunctionofethnicity,damage,conditioningtreatment,andvarious environments. Variouscellularstructuresofhumanhairand?nesublamellarstr- turesofthecuticleareidenti?edandstudied. Nanomechanicalpropertiessuchas hardness,elasticmodulus,tensiledeformation,fatigue,creep,andscratchresistance arediscussed. Nanotribologicalpropertiessuchasroughness,friction,andadhesion are presented, as well as investigations of conditioner distribution, thickness, and bindinginteractions. Tounderstandtheelectrostaticchargebuilduponhair,surface potentialstudiesarealsopresented. Thebookshouldserveasareferencebookonthebiophysicsofhumanhairand hairtreatments. TheresearchreportedinthisbookwassupportedbyProcter&GambleCo. in Cincinnati,Ohio,andKobe,Japan. IwouldliketothankCarmenLaTorrewhohad assistedinvariouspublicationsonhairresearch. Iwouldalsoliketothankmywife Sudha,whohasbeenforbearingduringthepreparationofthisbook. Powell,OH BharatBhushan November2010 v Contents 1 Introduction-Human Hair, Skin, and Hair Care Products...1 1. 1 HumanHair ...1 1. 1. 1 TheCuticle ...3 1. 1. 2 TheCortexandMedulla...6 1. 2 Skin...7 1. 3 HairCare:CleaningandConditioningTreatments,andDamaging Processes ...10 1. 3. 1 CleaningandConditioningTreatments:Shampoo andConditioner...13 1. 3. 2 DamagingProcesses...18 1. 4 OrganizationoftheBook ...19 2 Experimental Methods...21 2. 1 ExperimentalApparatuses...23 2. 2 ExperimentalProcedure ...26 2. 2. 1 StructuralCharacterizationUsinganAFM...26 2. 2. 2 SurfacePotentialStudiesUsingAFM-Based KelvinProbeMicroscopy...29 2. 2. 3 NanomechanicalCharacterizationUsingNanoindentation ...30 2. 2. 4 InSituTensileDeformationCharacterizationUsingAFM ...32 2. 2. 5 Macroscale Tribological Characterization UsingaFrictionTestApparatus...33 2. 2. 6 Micro/nanotribologicalCharacterizationUsinganAFM...35 2. 3 HairandSkinSamples ...41 3 Structural Characterization Using an AFM ...45 3. 1 StructureofHairCrossSectionandLongitudinalSection ...45 3. 1. 1 CrossSectionofHair...45 3. 1. 2 LongitudinalSectionofHair...45 3. 2 StructureofVariousCuticleLayers...48 3. 2. 1 VirginHair...48 vii viii Contents 3. 2. 2 ChemicallyDamagedHair...50 3. 2. 3 Conditioner-TreatedHair...52 3. 2. 4 EffectofHumidityonMorphologyandCellularStructure ofHairSurface...54 3. 3 Summary...55 4 Nanomechanical Characterization Using Nanoindentation, Nanoscratch, and AFM...57 4. 1 Hardness,Young'sModulus,andCreep...

This book summarizes the authority of regulatory agencies and programs as they pertain to the cosmetic industry, offers practical advice on how to operate within the regulatory environment, and introduces scientific and regulatory issues that are likely to have an impact on cosmetic manufacturers.

With malpractice insurance premiums on the rise, and insurance rates for the practicing anesthesiologist at an all time high, it is important, now more than ever, to have a single source reference related to both anesthesia and analgesia and how they both relate to dermatologic surgery. This book provides comprehensive coverage on the therapeutic usage of anesthesia and analgesia during dermatologic surgical procedures, providing basic concepts, as well as step-by-step descriptions of the various techniques involved. Written by an international group of contributors, Anesthesia and Analgesia in Dermatologic Surgery: is the first book of its kind to present both anesthesia and analgesia techniques in a single source volume covers the basic principles of regional and local anesthesia with respect to anatomy, local anesthetic agents, and techniques examines new eutectic mixtures that penetrate through the skin's membrane, enabling doctors to use analgesia over anesthesia for a wide range of superficial surgical procedures, including the harvesting of split skin grafts, laser surgery, electrosurgery, epilation, and skin biopsy discusses the use of nerve blocks as safer alternatives to local anesthesia contains a full chapter dedicated to the pediatric patient, and the specific concerns when relating anesthesia to the pediatric patient

Covering the entire array of photodermatological topics necessary to stand at the head of this burgeoning discipline, this source contains expertly written chapters that offer recommendations and guidelines from opinion-forming international authorities. Reviewing the entire range of photodermatoses, as well as the management, treatment, identification, and assessment of these conditions, this source includes discussions of narrow and broadband UVB, PUVA, photopheresis, UVA1 therapy, and photodynamic therapy, the principles and medical and cosmetic uses of lasers and similar sources, and appendices on phototesting, photopatch testing, and the development of phototherapy units to stand at the forefront of this burgeoning dermatological subject.

Filling a gap in the literature, this atlas stands as a unique authoritative source to thoroughly review the many immunofluorescence patterns seen in immunodermatology for conditions such as immunobullous diseases, connective tissue diseases, vasculitis, and other miscellaneous dermatologic disorders.

Treating patients with facial dermatoses is an important aspect of dermatological practice, and this color-illustrated monograph on the most important disorders and their current management will be of value to all dermatologists in training, as well as those who are established in the profession and in allied specialties.

This concise, comprehensive guide is divided into two sections; nails and the skin. Each section includes information on the types of infections, aetiology, diagnostic procedures, such as sampling techniques, and therapy, including topical, systemic and adjunctive.

Containing 350 illustrations, tables, and equations and covering AAPS/FDA guidelines for the experimentation and analysis of in vivo and in vitro percutaneous absorption, this reference provides comprehensive coverage of the development, preparation, and application of topical and transdermal therapeutic systems. Recognized international experts discuss the bioequivalence of dermatological and transdermal dosage forms. They explore the biochemistry and treatment of skin diseases, the structure and function of the skin, adverse dermal responses to drug formulations, mechanisms of drug transport through barrier membranes, and methods for measuring and modulating percutaneous permeation.

Key Features: 1. Provides inclusive and consolidated contents on disorders of female genital skin and mucosa. 2. Features high-quality illustrations and impressive treatment algorithms, making it a ready reckoner for dermatologists, gynaecologists, and general physicians. 3. Facilitates diagnosis and further management of vulvar disease in the skin of colour, thus optimizing patient care.

Shows how to validate scientifically the marketing claims of chemically stable and well-balanced products to withstand adequately the challenge of competitors and government regulators. The book describes techniques for substantiating properties, such as moisturization, mildness, conditioning and cleansing, as well as the performance of deodorants and antiperspirants, and the effectiveness of acne products. It discusses technologies that help eliminate animal testing in product development.

- Not only written by experts but the content of each of the chapters has also been peer-reviewed.

- Presents a step-by-step approach to the treatment of chronic wounds.

- For dermatologists, but also many other medical disciplines such as general practitioners and family physicians who also treat chronic wounds.

Dermatology: An Illustrated Colour Text is an ideal resource for today's medical student, hospital resident, specialty registrar in dermatology or internal medicine, specialist nurse or family doctor. It presents the subject as a series of two page 'learning units', each covering important aspects of clinical dermatology. These units use an unsurpassed collection of colour clinical photographs of all major dermatological conditions, concise yet comprehensive text and Key Point boxes to aid quick access to information and examination preparation. They incorporate summaries of the essential skin biology and associated basic sciences that underpin clinical practice, as well as advice on established and emerging dermatological treatments. Guidance is also given to dermatological emergencies, and to the most useful online resources for updates and further reference. Building on previous success, this seventh edition has been fully revised throughout. The accompanying interactive eBook version completes this superb learning package. New and enhanced coverage of key and emerging areas - including biologic therapies, dermoscopy, skin surgery, cosmetic surgery, skin cancer, pigmented skin, male and female genital dermatoses, lymphomas of the skin, paediatric dermatology, psychodermatology, rosacea, benign skin tumours, immunological tests, molecular genetics, connective tissue diseases of the skin and skin procedures New line drawings and photographs incorporated throughout to further improve clarity and ensure comprehensive visual coverage of important dermatological conditions (Printed book) Includes downloadable eBook version with bonus material - incorporating self-test flashcards and multiple Information is presented in easy to access text layouts. Highly illustrated with over 400 colour photographs and drawings. Summary boxes are included for revision purposes. Covers the subject from basic molecular mechanisms through to the principles of medical and surgical treatment