'Year Book of Dermatology and Dermatologic Surgery 2010' brings you abstracts of articles carefully selected from more than 100 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice.

This issue of Dermatologic Clinics is the first of a two-part series examining Epidermolysis Bullosa. Guest Editor Dedee Murrell has assembled a panel of experts to pen articles on topics covering pathogenesis, clinical features, diagnosis, treatment, and international perspectives on EB.

As a result to the recent significant developments, both in the field of cutaneous pathology and clinical dermatology, many cutaneous neural tumors s are now being diagnosed by specialists like dermatopathologists, and treated by dermatologists or dermatologic surgeons. Cutaneous Neural Neoplasms provides an essential aid in diagnosis by discussing the cardinal clinico-pathologic features of cutaneous tumors relevant to these specialists. It covers detailed pathologic features, and their differential diagnosis. Applicable special diagnostic techniques are extensively illustrated. Whenever relevant, key therapeutic recommendations are provided. Unique topics covered include; Discussion of plexiform neural tumors and their imitators, with special relevance to neurofibromatosis Neoplasms with atypical microscopic features, but benign clinical behavior, which are often misdiagnosed as malignant tumors New developments in cutaneous neural tumor diagnosis and recently described neural tumors The authors approach each entity by presenting clinical and/or gross photographs when relevant with discussion of the clinical features, followed by the tabulated list of key pathologic features with corresponding histopathologic illustrations. Therapeutic recommendations are summarized. This book is intended to fill a major gap in the currently available resources for practicing physicians, and will provide them with an appropriate knowledge base to handle these challenging tumors in the most up-to-date fashion.

Providing the most comprehensive, up-to-date coverage of this exciting biomedical field, Handbook of Photomedicine gathers together a large team of international experts to give you a complete account of the application of light in healthcare and medical science. The book progresses logically from the history and fundamentals of photomedicine to diverse therapeutic applications of light, known collectively as phototherapies. It facilitates your understanding of human diseases caused by light, the rationale for photoprotection, and major applications of phototherapy in clinical practice. The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression. The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.

This new reference covers the top 100 pearls in cutaneous oncologic, nail and cosmetic dermatologic surgery, giving you at-a-glance access to some of the best know-how in the field. Organized in a consistent format, and illustrated with full color photographs and explanatory line drawings, this is the perfect tool to help you improve the level of care you offer your patients. Whether you're new to the field or you've been practicing dermatologic surgery for years, you'll consider this book one of your most valuable resources. Fills a gap in the field by bringing together material that is rarely gathered in one book. Includes expert hints and tips on avoiding common pitfalls in cosmetic and dermatologic surgery. Illustrates each pearl with line drawings and photographs to put it into clinical context.

The role of Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology provides current and concise scientific appraisal of the efficacy of foods, nutrients, herbs, and dietary supplements in preventing dermal damage and cancer as well as improving skin health. This important new volume reviews and presents new hypotheses and conclusions on the effects of different bioactive foods and their components derived particularly from vegetables, fruits, and herbs. Primary emphasis is on treatment and prevention of dermal damage focusing on skin cancers with significant health care costs and mortality. Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology brings together expert clinicians and researchers working on the different aspects of supplementation, foods, and plant extracts and nutrition and skin health. Their expertise provides the most current knowledge in the field and will serve as the foundation for advancing future research.

The thoroughly updated 3rd Edition of this highly regarded text continues to provide the latest therapeutic and surgical information on nail disease. A new signs-oriented section guides you to disease-specific information and simplifies diagnosis. The new, streamlined format includes bullet lists . cross-references . "Therapy" and Key points" highlights for easy reference . and full-color artwork throughout, as well as a larger page size that accommodates bigger photographs. In addition, many illustrations have been added to elucidate complex basic science. Provides the most reliable and comprehensive treatment information available-fully revised to include the latest therapeutic and surgical knowledge. Uses a disease-oriented chapter format. Presents a new signs-oriented section that quickly guides you to disease-specific information. Provides new coverage of the diagnosis and treatment of onycholysis and chronic paronychia. Ranks therapy according to the available evidence, allowing you to treat your patients with confidence. Includes essential new information on genetics and future developments. Features outstanding new full-color photographs and illustrations-many new to this edition-that clearly depict nail disease and basic science concepts. Uses a more streamlined format for easier readability and access to important points. Features 4 new associate editors, presenting fresh perspectives and new, expert contributions to nail disease and treatment. With 4 additional associate editors and 15 contributing experts.

Molecular Diagnostics in Dermatology and Dermatopathology presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with traditional histologic approaches, and discussions of regulatory, ethical, legal, economic issues and newer technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists."

The diagnosis and treatment of common dermatologic problems is a critical area of skill and knowledge for primary care physicians. According to the US Department of 1 Health and Human Services, patients present to their physicians a skin rash as their chief concern for nearly 12 million office visits each year. In 73% of these office visits, patients see their internist, family physician, or pediatrician. In this respect, astonishingly, primary care clinicians see far more skin disease in their offices than dermatologists. Dermatology Skills for Primary Care: An Illustrated Guide advances the targeted skill and knowledge base of primary care physicians, as well as the collaboration between dermatologists and primary care physicians, by its wise choice of organization, scope, and approach. Dermatology Skills for Primary Care: An Illustrated Guide by Drs. Trozak, Tennenhouse, and Russell is an important addition to the dermatology literature because it has been written collaboratively by a skilled dermatologist and two excellent academic family physicians. As such, the book superbly targets the depth and scope of needs of primary care practitioners in the field of dermatology.

"Skin Cancer: A Practical Approach" presents a comprehensive and up to date overview on skin cancer. With an emphasis on practical aspects that will set the basis for guidelines of treatment, the volume presents different diagnostic tools to help physicians obtain the proper diagnosis.

Written by a worldwide base of experts selected on their recognized expertise on the different themes discussed, "Skin Cancer: A Practical Approach" is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, dermatologists, general surgeons, and veterinary oncologists

Fatty acids play an important role in the barrier function of skin and represent a major source of proinflammatory mediators such as prostaglandins, leukotrienes and other lipids in inflammatory skin disorders. This book combines the two major functions of fatty acids in skin biology. In the first part the biosynthesis of fatty acids in skin with its role in barrier function as well as the role of dietary fatty acids on skin cell function and in the treatment of inflammatory skin diseases is presented. The second part deals with skin as a source of proinflammatory eicosanoids, especially with the keratinocyte as a major cellular source. Metabolism of eicosanoids in skin, its role in psoriasis and atopic dermatitis as well as pharmacological inhibition of eicosanoid biosynthesis is reviewed. The book finishes with a chapter describing the methods used for quantification of fatty acids and derivatives in skin inflammation. Anyone interested in skin physiology would benefit from the overviews about the two sites of fatty acids' function in skin integrity and in skin inflammation.

Epidermolysis bullosa (EB) is a heterogenous group of genodermatoses characterized by the formation of blisters and erosions on skin and mucous membrans from birth on. The cause are mutations in the genes of structural proteins of the junction between epidermis and dermis. This book deals with the treatment of this skin disease itself and its many extracutaneous complications. There is no previous book which has been focused on the therapy and it will be based on evidence-based data derived from the worlds largest cohort of inherited EB-patients, the American EB Registry. An important chapter will discuss gene therapy in hereditary EB which has been recently successfully performed within a localized skin site on a single EB patient as a proof-of-principle test. Given its unique collective contents, the monograph will provide the primary source for clinical informations of this oftentimes severe multiorgan disease."

In the past decade it has become increasingly clear that psoriatic disease, both of the skin and joints, can be a significant diagnostic and therapeutic challenge for the physician and a debilitating illness for the patient. At the same time, advances in genetics and immunology have increased our understanding of the pathophysiology of psoriasis and psoriatic arthritis. This text contains a comprehensive discussion by an international group of experts in psoriatic disease of the pathomechanisms, genetics, diagnosis, and treatment of psoriasis and psoriatic arthritis. The information is presented in parallel in order to emphasize the similarities and differences between these two diseases that so commonly occur together. We believe that this approach will make this text an important resource for all practitioners who treat patients with psoriasis and psoriatic arthritis.

Hair transplantation is in demand worldwide, but because Asian hair tends to be more sparse and coarse than Caucasian hair, transplantation procedures need to be adapted to Asian patients. This book, exclusively devoted to Asian hair, is a complete and comprehensive text written by a group of authors sharing their experience in their specialized fields of hair restoration. Included are many practical tips as well as chapters on regional transplantation such as eyebrows, eyelashes, sideburns, beards, and mustaches, in addition to the usual scalp hair restoration. With its many illustrations, the book gives readers a complete knowledge of hair restoration surgery and provides a quick, easy-to-use reference on Asian hair and the differences in patients' demands. With an influx of new physicians in this challenging field of medicine, further education and training are imperative and must be available to provide a high standard of medical practice. This compilation meets that objective and ultimately makes the valuable contribution of restoring patients' self-confidence.

This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF inhibitors are effective for a short period of time, but there is little hope that this drugs as single agents will lead to durable benefit in a majority of patients. Among scientists and researchers who work in drug discovery, there is a lot of interest in the development of molecularly targeted cancer agents. Namely, the identification of a molecular target, the selection of molecules which effectively inhibit this target. What is starkly different about the development of this class of compounds, however, is that the mechanism of action of these agents are not as straightforward as was once previously assumed and the mechanisms of resistance that tumor cells employ to evade complete destruction are unlike any that have been described before. These discoveries in addition to utilization of modern molecular biology techniques have led to a series of hypotheses regarding which other types of molecules could be used in combination with BRAF-inhibitors in hopes of revolutionizing the potential of therapeutics in melanoma.

Melanoma is one of the most types of cancer. When melanoma is detected at an early stage, treatment is highly successful, but outcomes can be poor when the disease is advanced. There has been significant progress in our understanding of the molecular biology, genetics, and immunology of melanoma over the past decade. This has been accompanied by rapid advances in therapeutic strategies for patients with melanoma. This book provides the clinician and the researcher with a broad understanding of the molecular and cellular pathogenesis of melanoma, explores the clinical characteristics and criteria for clinical and pathological staging of the disease, and provides an overview of current and evolving treatment strategies in the adjuvant, metastatic, and preventive settings. The treatment of special populations and rare variants of melanoma that often present particular clinical challenges is also covered. Authored by international experts in melanoma biology and clinical management, this volume concisely explains how to diagnose, treat, and prevent melanoma while reviewing advances in basic science and providing an overview of innovative approaches still under development.

Strong body odor is a condition for which, until now, there have been few treatment methods. The Japanese authors, encouraged by the willingness of Oriental patients to undergo radical treatment, have developed the subcutaneous tissue shaving method, which eliminates the condition in a very short period of time without ugly scarring. The book Human Body Odor not only introduces the completely new subcutaneous tissue shaving method, it also questions conventional theories on the hair cycle itself and throws a new hypothesis about the process of hair generation and regeneration into the scientific arena. This could even lead in the future to a formula for retarding hair loss! Developed over the past twenty years, the authors' new surgical method for the radical treatment of bromidrosis represents a landmark in cosmetic surgery and dermatology!