Proof of the efficacy of dermatological products is a prerequisite for clinical testing and registration. Now, efficacy claims for cosmetics must be equally substantiated. This book provides a concise, practical but comprehensive overview of experimental models used to screen, develop and select dermatological and cosmetic formulations. The authors are recognized specialists in their field and use a standardized approach to the projects facilitating the reading for the stressed scientist, for the R+D managers general view as well as for the beginners in the field.

Written by two leaders in the field of pediatric dermatology, this classic text provides both detailed content for the specialist and easily accessible information for the non-dermatologist and less experienced clinician. Paller and Mancini - Hurwitz Clinical Pediatric Dermatology, 6th Edition, comprehensively covers the full range of skin disorders in children, offering authoritative, practical guidance on diagnosis and treatment in a single volume. This award-winning, evidence-based text has been fully revised and updated, and is an essential resource for anyone who sees children with skin disorders. Features new content outline boxes for faster navigation, hundreds more clinical images, and authors' tips for the diagnosis and treatment of pediatric skin diseases. Contains updated, evidence-based guidance and the latest drug developments and disease classifications. Provides a careful balance of narrative text, useful tables, and 1,300 high-quality clinical photographs, helping you recognize virtually any skin condition you're likely to see. Includes a greatly expanded discussion of atopic dermatitis and psoriasis and new therapeutic approaches for treating genetic disorders and systemic diseases such as ichthyoses and rheumatologic disorders. Discusses new tests for subclassifying disease, such as the myositis-specific antibodies of juvenile dermatomyositis, genotyping, and immunophenotypes of inflammatory skin disorders. Contains new and updated tables on psoriasis co-morbidities, genetic syndrome classifications, acne therapies, pediatric histiocytoses, PHACE syndrome criteria, HSV therapies and juvenile dermatomyositis. Features updated sections on infections, exanthems, vascular disorders, dermatoses and genodermatoses. Discusses hot topics such as the use of stem cell and cell therapy, as well as recombinant protein, for treating epidermolysis bullosa; the resurgence of measles; congenital Zika virus infections; and much more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Optical imaging is a rapidly emerging imaging technique that has been successfjully translated into biomedical applications ranging from clinical diagnosis to molecular biology. This book includes an introductory section to explore various optical imaging devices and their functionality and roles for biomedical applications such as dermatology and ophthalmology. Recent developments as exemplified with the authors research are explored in detail. In depth discussion of other disease conditions and their diagnosis with optical imaging techniques are also covered.

The skin is often the first organ to show that a serious disease exists in the body. Too often, clues from the skin are missed or neglected when examining a patient. From dog bites that don't heal to the dermatological effects of a vegan diet, 50 Cases in Dermatological Medicine demonstrates the astonishing variety of cutaneous responses that occur in a range of underlying pathologies. This fascinating treatise presents fifty cases from King's College Hospital that show the important relationship between dermatology and other medical disciplines.

The day-to-day responsibility for wound management is a role usually undertaken by nurses. It includes assessing the wound, selecting an appropriate treatment, and evaluating the patients' progress. In order to do this effectively the nurse needs to understand the healing process, recognize the factors which may delay wound healing, understand how wound healing can be optimized, know how to recognize complications if they arise and know how to treat them.

This text, specifically written for community nurses, including practice nurses, provides a picture of wound healing for both acute and chronic wounds that may be encountered in a community setting. An overview of the function of the skin and phases of wound healing are examined prior to looking at the relationship between wound healing and the patients' health and lifestyle.

The reference is written in a question-and-answer format, and includes relevant case studies.

There is a great need for a visual resource to document, with clarity, the possible outcomes of surgery, including side effects and complications, and how these outcomes vary from individual to individual. Using a straightforward approach, Outcomes of Skin Surgery: A Concise Visual Aid is an easy-to-consult and highly illustrated reference for surgeons and patients alike. This text takes a major step forward in establishing a realistic basis for the decision-making process during a consultation. Procedures highlighted in the text include: the excision of benign and malignant tumors diagnostic biopsies cryosurgery curettage for superficial lesions photodynamic therapy

This exceptional reference examines current and emerging topical and transdermal drug delivery systems and their influence on the uptake, absorption, and potency of released compounds. It presents detailed information on such important topics as the kinetic properties and chemical interactions of the skin, drug candidate, and transport vehicle to avoid skin irritation and inflammation, and enhance drug performance and distribution. Containing more than 1,700 references, tables, and equations. Transdermal drug delivery, 2nd Ed. is a timely source for industrial, clinical, and research pharmacists.

This book presents a wide variety of cutaneous features of systemic sclerosis under one cover as cutaneous manifestations are often the first to appear and help in diagnosing this condition early. It has a multidisciplinary approach as systemic sclerosis is a multi-system disorder which comes under the purview of various medical specialties like dermatology, rheumatology and nephrology. Numerous cutaneous features are illustrated with explanatory notes. This book would help the students, teachers and professionals in identification, followed by subsequent treatment and management at an early stage. Key Features Focuses exclusively on systemic sclerosis Includes diagnostic tips Explores systemic sclerosis in dark skinned people Consists of key points at the end of each chapter Discusses diagnostic algorithms and flow charts

Raynaud's Phenomenon is an auto-immune disorder which causes poor circulation in the digits and may affect up to 10% of all women. It is characterized by episodic blanching or cyanosis of one or more digits on exposure to cold; the phenomenon may occur with or without an underlying disease. This monograph presents the most up-to-date knowledge concerning Raynaud's Phenomenon, both as a primary disease and as the secondary result of an underlying disease, drug therapy or occupational exposure. The book reviews anatomy, physiology, the clinical picture, prevalance of the disease, diagnosis, prognosis, physiology and pathophysiology, and treatment.

Contains current American Association of Pharmaceutical Scientists/Food and Drug Administration (AAPS/FDA) guidelines for the experimentation and analysis of in vivo and in vitro percutaneous absorption This up-to-the-minute reference provides comprehensive coverage of the latest advances in the development, preparation, and application of topical and transdermal therapeutic systems-exploring the biochemistry and treatment of various skin diseases as well as the structure and function of the skin, adverse dermal responses to drug formulations, mechanisms of drug transport through barrier membranes, and methods for measuring and modulating percutaneous permeation. Offers contemporary discussions on the bioequivalence of dermatological and transdermal dosage forms With more than 1800 useful references and 350 illustrations, tables, and equations, Dermatological and Transdermal Formulations is an essential source for cosmetic and pharmaceutical scientists, dermatologists, toxicologists, agrochemists, regulatory agency personnel, and upper-level undergraduate and graduate students in these disciplines.

Ranging from the Egypt of the Pharaohs to the present day, Historical Atlas of Dermatology and Dermatologists offers a unique insight into the history of dermatology and the influences that led to present practice. It sheds new light on the emergence of dermatology as a separate medical speciality and on some of the key players who have contributed to its development. Arranged as an illustrated time-line this volume features an exceptional range of historical plates such as 'Molluscum contagiosum', from Thomas Bateman's Delineations of Cutaneous Diseases, 1817, an 1869 painting of ichthyosis hystrix by Carl Heitzmann, and early experiments in ultraviolet therapy by Finsen and colleagues in 1903. The authors have selected individuals representative of each era, workers who dealt seriously with the dermatologic concerns of the day, or who through their opinions or behavior project the color and ambience of the period in which they lived. They have included typical examples of the books, journals, instruments, and devices that made up the annals and paraphernalia of the speciality as it evolved. In order to know where you are going, you have to know where you've been. The field of dermatology has been fragmented in the last 30 years. It is becoming increasingly difficult to answer the simple questions: What is dermatology and what is a dermatologist? Research dermatology, dermato-histopathology, pediatric dermatology, and the explosion of surgical techniques have all made their mark on how dermatology is practiced. Historical Atlas of Dermatology and Dermatologists explores the development of this field and where it may be going in the future.

Since skin forms the interface between the human body and the environment, its mechanical properties are important in health and disease. Bioengineering of the Skin: Skin Biomechanics gives a thorough introduction in the biological basis of skin biomechanics. It explains the non-invasive methods that allow measurement of the mechanical properties of the skin focusing on commercially available instruments.

Written by internationally leading experts in the field of non-invasive measurement technology of the skin, this volume describes the anatomy, biochemistry, physiology, and pathology of skin biomechanics. It explains in detail how to measure skin mechanic properties and how to use these measurements in the development of drugs and cosmetics.

""Sun Protection in Man"" looks at the beneficial and harmful effects of solar radiation. The physiological consequences of sun exposure have been systematically studied starting at the end of the nineteenth century and we now have accumulated knowledge about how Caucasian and Asian skins reacts to solar radiation. The chemical effects of solar ultraviolet radiation have been analyzed with particular emphasis during the second half of the twentieth century. Research on micro-organisms has allowed us to understand the mechanisms of UV-induced mutagenesis and photosensitization. Studies with laboratory rodents have opened the path to the understanding of UV-induced immune-depression, carcinogenesis, photo-damage and photo-aging. The results of these studies have enabled other scientists to investigate the same phenomena in human organs such as the skin and the eye. UV radiation damages hair, as well. The present knowledge in these fields is summarized in some of the chapters of this monograph.
Mass phenomenon in Europe with the generalization of summer vacations which were a consequence of social reforms introducing the concept of "paid vacations." This created a need for protection and opened a market for sunscreens.
This monograph is concerned with sun protection as a whole and is not just "another book on sunscreens." Nonetheless, in these days of general concern, it is important to learn about the efficiency of sunscreens. Several authors discuss how to reduce the number of impinging photons and explain why sunscreens seem to offer less protection than expected. Guidelines are given on how to use sunscreens in everyday life, which are expressed rigorously though clearly, for access to the common reader.
Our knowledge on the relationship between sun and humans is at the early stages of development. Industrial and commercial activities are concerned by the development of this knowledge, and rules have been and will be promulgated to guarantee efficacy and safety of sun-products. It is hoped that this monograph will be of interest to the scholar, the layman and the legislator.

This book is designed to help develop a GPs skill in disease recognition and treatment. For this reason it approaches the subject from a symptoms-specific rather than a disease-specific angle.
It contains approximately 60 high-quality illustrations and explanatory text. It is ideal for use as an instant reference in day-to-day clinical practice or as part of ongoing CME. It would be ideally suited for those studying for the Diploma in Practical Dermatology

This book makes reference to all the main skin conditions - eczema, acne, vitiligo, psoriasis, dermatitis and alopecia amongst others - and makes extensive use of case studies and vignettes. It is this blend of theory and practical experience that is the hallmark of the book. All those concerned with dermatological problems will find something of value in it and should find it a valuable addition to their resources.

Chemotherapy and radiotherapy for cancer can have devastating side effects on the skin of a patient. This innovative guide for both dermatologists and oncologists gives a good introduction both to therapy regimes and to dermatological management for medical professionals treating their patients.

Skin lesions are often the first sign for an endocrine disease. Their description is thus of relevance for early diagnosis and treatment of endocrine disease for specialists in endocrinology as well as in dermatology.

Lavishly illustrated, this book describes the clinical and histological features of skin lesions observed in endocrine diseases. All features are reader-friendly structured and written in the language of dermatologists in order to enable a simple association between the features observed and the endocrine etiology.

This book includes 200 clinical cases which present as emergencies. Congenital and acquired conditions affecting all body systems in infants and children are covered, including allergy, abuse, burns, fractures and other trauma, feeding problems, foreign bodies, genetic disorders, infections, poisoning, haematology, oncology, and much more. Cases appear in random order, reflecting actual practice in emergency medicine, and reinforcing skills in investigation, diagnosis, and treatment. It is superbly illustrated with high-quality radiographic images and photographs and is indispensable for all health professionals dealing with emergencies involving children.

Principles of Polymer Science and Technology in Cosmetics and Personal Care

This concise, comprehensive guide is divided into two sections; nails and the skin. Each section includes information on the types of infections, aetiology, diagnostic procedures, such as sampling techniques, and therapy, including topical, systemic and adjunctive.

Skin reactions to drugs are a ubiquitous problem-the most commonly observed drug sensitivity observed in a wide range of specialties. Skin Reactions to Drugs emphasizes the mechanisms and clinical and laboratory proof of a cause-and-effect relationship between drugs and adverse reactions. It discusses the technique of drug challenge, which has been extensively developed in Finland, but not commonly practiced in the rest of the world.
In this textbook, 12 of the most common drug eruptions are described both clinically and histologically. It features a chapter on systemic contact dermatitis and also addresses cutaneous adverse drug reactions that appear in HIV-infected patients. 40 full-color photographs provide vivid examples of the reactions being discussed. A highly practical resource for practicing physicians and other health care workers, Skin Reactions to Drugs represents the platinum standard of research conducted on the causation of certain adverse reactions of skin.

There are many changes in the skin, hair, and nails during and after pregnancy. Patients are certainly aware that those changes are occurring, but few physicians and even fewer patients know how to predict the course of those changes. Pigmentary changes occur, but are they permanent? Can they be prevented or reversed? Hair may become thicker during pregnancy, only to fall out in the postpartum period. When will hair stop falling out? Will it grow back? What hormonal changes are occurring to produce these effects on the skin, hair, and nails? Will those hormonal changes affect other organs? Some cutaneous manifestations of pregnancy are common and recognized by most physicians. Abdominal striae, for example, are easily identified, but physicians have many questions about them. Why do they develop? Can they be prevented or treated? Other cutaneous manifestations of pregnancy are less common and recognized by few. For example, pruritic urticarial papules and plaques of pregnancy is a debilitating condition that is treatable once diagnosed. Even more important than the treatment, the knowledge imparted to a worried mother that her child will be fine and that the condition is se- limited is priceless; but the condition must first be recognized by the patient's physician. All of these questions and conditions are addressed in this extraordinary book. Pigm- tary disorders are addressed in detail in Chap. 2.

Botulinum toxin injections are the most used and best-known aesthetic treatment internationally, but there remain a number of problematic topics and suboptimal results. Here an internationally known expert and his contributors explain the scientific background and aesthetic principles that can help clinicians achieve better results in problem cases.

This unique reference provides concise, single-source coverage of the clinical, research, and therapeutic aspects of dermatological problems associated with bacteria, fungi, and viruses.
Introduces many novel antifungal, antibacterial, and antiviral agents
Highlighting the molecular biology as well as risk - benefit ratios of new diagnostic and treatment modalities, Cutaneous Infection and Therapy
evaluates the role of antimicrobial soaps in personal hygiene and research on preoperative skin preparation and infection rates
discusses reasons for the reduced risk of infection using occlusive wound dressings
explains the epidemiology, presentation, pathophysiology, and treatment of athlete's foot and fungal diseases of the scalp
presents new oral antifungals for the treatment of onychomycosis
examines the advantages and disadvantages of preparations to treat superficial fungal infections
addresses oral candidiasis in HIV infection and the resistance to antifungal therapy in AIDS patients
reviews the patterns of candidiasis in children and current approaches to antifungal therapy
covers the epidemiology, implications, and management of herpes in pregnant women and newborns
and much more

This book demonstrates evidence of a new microorganism infecting a person complaining of a dermopathy and fibers spontaneously exiting the dermis who was diagnosed with delusional parasitosis. The organism is likely a fungus that lives beneath the epidermis with the ability to infect common fibers including cotton, feathers and hair follicles.