This detailed book presents a technical overview and practical methodology of a variety of antibody array formats and technologies. As advantages and disadvantages of antibody array types are explored, the volume also delves into practical applications of antibody arrays pertaining to investigations of specific research topics and biological processes as well as guidance on the methods of processing, analysis, and storage of array data. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Antibody Arrays: Methods and Protocols aims to empower the reader with the information required to select the most appropriate array for their research application, with the technical knowledge to use and process the array, and with the knowledge to perform analysis that realizes the maximum benefit from the data generated.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects - properties, synthesis, reactions, physiological and industrial significance - of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

This volume gathers a selection of original articles and reviews on timely topics about the application of Taurine in human health written by members of the International Taurine Society, including COVID-19, cancer, heart disease, and diabetes, among others. Chapters are written by Taurine experts across the globe in North and South America, Asia, and Europe. A majority of the articles are based on original studies recently carried out in individual laboratories worldwide. The book is divided into eight parts, each covering a unique aspect of Taurine. Each section will highlight new research findings on Taurine and its application in various human systems, including the nervous system, immune system, and cardiovascular system, to combat disease. The first section covers COVID-19, the dominant health event of 2020. Experts will explore and clarify the potential therapeutic effectiveness of Taurine against COVID-19. The volume will promote further research into the application of Taurine in human health, and will be of use to a wide audience, including basic and clinical scientists, pharmaceutical and nutraceutical companies, and libraries.

The book offers advanced students, in 7 volumes, successively characterization tools phases, the study of all types of phase, liquid, gas and solid, pure or multi-component, process engineering, chemical and electrochemical equilibria, the properties of surfaces and phases of small sizes. Macroscopic and microscopic models are in turn covered with a constant correlation between the two scales. Particular attention was given to the rigor of mathematical developments. Besides some very specialized books, the vast majority of existing works are intended for beginners and therefore limited in scope. There is no obvious connection between the two categories of books, general books does not go far enough in generalizing concepts to enable easy reading of advanced literature. The proposed project aims to give readers the ability to read highly specialized publications based on a more general presentation of the different fields of chemical thermodynamics. Consistency is ensured between the basic concepts and applications. So we find, in the same work, the tools, their use and comparison, for a more general macroscopic description and a microscopic description of a phase.

Covers potential energy storage (rechargeable batteries and supercapacitors) and energy conversion (solar cells and fuel cells) materials. Develops theoretical predictions and experimental observations under a unified quasi-particle framework. Illustrate up-to-date calculation results and experimental measurements. Describes successful synthesis, fabrication, and measurements, as well as potential applications and near future challenges.

This book covers the simulation of evaporating saltwater falling films with and without turbulence wires. The methods presented within can be applied to a variety of applications including the food and pharmaceutical industry, as well as in nuclear technology. This topic is ideal for researchers in chemical engineering.

The first accessible text on the topic of animals as environmental predictors, bringing together the literature from as far back as 18th century through to the present day. - Covers wider terrain than other titles in a relatively unexplored subject area. The text discusses climate change (highly topical) and how animals may be able to be used to predict future weather and climatic events. There is international potential as the climate challenge is global, and the examples span worldwide case studies. The sources used include myths, anecdotes, news articles and stories backed up by relevant scientific literature in international peer-reviewed journals. Each chapter starts with a short fictitious story to set the scene and anecdotes from indigenous cultures are especially interesting. The author draws on his vast expertise in biochemistry and cell biology. The science does not impede the less technical reader, due to the engaging mix of stories, anecdotes, personal observations and scientific underpinnings.

This detailed volume presents a series of protocols dealing with different aspects of inclusion body (IB) processing, from cloning procedures to purification of refolded product. Commencing with chapters on upstream processing, looking into different expression strategies for IB production, the book continues with downstream applications, highlighting early protein purification and subsequent analytics, as well as success stories of IB-based processes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Inclusion Bodies: Methods and Protocols serves as an ideal resource for facilitating diverse aspects of IB processing.

My professional interest in antimicrobial agents and contamination control goes back 50 years to my tour as a microbiologist in a field hospital in Europe during World War II. With no experience and relying solely on a military handbook, I prepared thermometer trays with jars of blue bichloride of mercury and pink isopropyl alcohol. A preliminary typhoid diagnosis of one of our cooks resulted in the need for lab testing. His stool specimen and its subsequent disposal was my problem. My handbook said bum it. So burn it T did, in a five-gallon can with gasoline. Flames shot up almost six feet, and my next mistake was to extinguish them with carbon tetrachloride. This resulted in the production of lethal phosgene gas. The hospital had a near disaster. I could say that at that moment I vowed to write a how-to book so that such stupidities could be avoided. Nevertheless, when I was offered the opportunity to edit this book I thought back on the need for a real, practical treatment of my subject. This book, then, is a practical handbook for technical service personnel and scientists who are not necessarily specialists in microbiology. It provides information on suitable antimicrobial agents appropriate to their particular problem-solving needs and information on the microbial groups contributing to the specific problem, their ecologies, and strategies for controlling their access to the area or material of interest.

Fluid Inclusion Effect in the Flotation of Sulfide Minerals gives a detailed introduction to how fluid inclusions affect the flotation of sulfide minerals. The book introduces the various fluids found in geology, detailing the properties of fluid inclusions and how to identify and analyze their composition. It gives the common chemical compositions of fluid inclusions, investigates the release of fluid inclusions in sulfide materials and some gangues, and presents the concentrations and solution chemistry of the released ions. Finally, the book considers the absorption mechanism and the interaction of some typical metal ions from fluid inclusions on the surface of sulfide minerals.

Access state-of-the-art research about trace element contamination and its impact on human health in "Trace Elements as Contaminants and Nutrients: Consequences in Ecosystems and Human Health." In this ground-breaking guide, find exhaustive evidence of trace element contamination in the environment with topics like the functions and essentiality of trace metals, bioavailability and uptake biochemistry, membrane biochemistry and transport mechanisms, and enzymology. Find case studies that will reinforce the fundamentals of mineral nutrition in plants and animals and current information about fortified foods and nutrient deficiencies.

Medicinal Plant Responses to Stressful Conditions discusses the effects of multiple biotic and abiotic stressors on medicinal plants. It features information on biochemical, molecular, and physiological strategies used to mitigate or alleviate detrimental effects of biotic and abiotic stressors. The book contains chapters featuring medicinal plants of importance covering subjects including genomics, functional genomics, metabolomics, phenomics, proteomics, and transcriptomics under biotic and abiotic stress of medicinal plants and their molecular responses. It suggests exogenous application of different types of stimulants to enhance medicinal plant production in such conditions. Features: * Details all aspects of biotic and abiotic stressors in various important medicinal plant species. * Chapters cover evidence-based approaches in the diagnosis and management of medicinal plants under stressful conditions. * Includes information on ways to mitigate effects from high salinity, drought, temperature extremes, waterlogging, wind, high light intensity, UV radiation, heavy metals, or mineral deficiencies. A volume in the Exploring Medicinal Plants series, this book is an essential resource for plant scientists, botanists, environmental scientists, and anyone with an interest in herbal medicine

This book provides a comprehensive overview of current biosurfactant research and applications. Public awareness of environmental issues has increased significantly over the last decade, a trend that has been accompanied by industry demands for climate-friendly and environmentally friendly renewable raw materials. In the context of household products, biosurfactants could potentially meet this demand in the future due to their low ecotoxicity, excellent biodegradability, and use of renewable raw materials. The diversity of this class of molecules, which has only been marginally tapped to date, offers only an inkling of their future application potential. However, there are two main obstacles to their widespread commercial use on the growing surfactant market: the lack of attractive and competitive production technologies, and the limited structural diversity of commercially available biosurfactants. Addressing both of these core issues, this book will provide readers with a deeper understanding of the role of biosurfactants, including future opportunities and challenges. Chapter "Environmental Impacts of Biosurfactants from a Life Cycle Perspective: A Systematic Literature Review" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

With a history that reaches back some 90 years, the Hume-Rothery rules were developed to provide guiding principles in the search for new alloys. Ultimately, the rules bridged metallurgy, crystallography, and physics in a way that led to the emergence of a physics of the solid state in 1930s, although the physical implications of the rules were never fully resolved. Even today, despite a revived interest brought about by the 1984 discovery of quasicrystals, much about the rules remains an enigma. Now almost a century after the rules were put forward, Hume-Rothery Rules for Structurally Complex Alloy Phases provides researchers with an insightful and applicable interpretation of the Hume-Rothery electron concentration rule. Invoking first-principle band calculations, the book emphasizes the stability of structurally complex metallic alloys (CMAs).Written by Uichiro Mizutani, long considered the most knowledgeable expert on both the history and science of Hume-Rothery, this seminal work - Offers a unified interpretation of phase stabilization mechanism of CMAs in different classes Explains how to determine the effective valency of transition metal elements Details establishment of d-states-mediated-FsBz interactions in strongly orbital-hybridizing systems Covers the contrast between e/a and VEC, two notions of electron concentration parameters and includes a way to differentiate between them in designing new alloys Explores strengths and shortcomings for the theory on alloy phase stability Discusses the latest take on electron concentration for gamma-brass This work summarizes the ongoing history of Hume-Rothery and reflects the theoretical studies that Professor Mizutani embarked upon to gain deeper understanding of the basic physics behind stabilizing effects related to electron concentration. It describes how metallic and coval

• Explores novel membrane materials and systems from preparation methods, materials selection, and their application in monitoring, fouling control, and performance enhancement. • Examines the mechanism of fouling prevention and cleaning in various electrically conductive materials. • Evaluates the scalability of antifouling materials and coatings, as well as electrically enhanced processes for monitoring and control in membrane separation technology • Assesses advantages and limitations of applying electrically conductive membrane systems to fouling control for specific water treatment applications. • Provides a critical review of scientific literature in the specialized area of electrical conductive materials and systems for membrane technology.

"Examines all known industrial processes using shape selective zeolites. Second Edition contains new, up-to-date information on the specific features that make zeolites shape selective, the role shape selective catalysis can play providing environmentally clean fuels, 12-membered oxygen ring systems, mesopore systems, and more."

The symposium on which this book is based originated after Tom Strom organized a successful American Chemical Society (ACS) symposium in March 2016, on the Posthumous Nobel Prize in Chemistry. Afterward, Vera Mainz pointed out that the chemists represented in that symposium and its subsequent symposium volume were "all dead white guys." The fact that only white men were included in the first symposium partly reflects the prevailing past (and continuing) gender imbalance in chemistry, but it also shows the power of the Matilda effect, first articulated by Matilda Joslyn Gage (1826-1898). The Matilda effect is an implicit bias against acknowledging the achievements of women scientists, whose work is often attributed to their male colleagues. An implicit bias is one which is not conscious or deliberate, but nevertheless real. The gender imbalance in the previous symposium was also noted in the on-line comments for the Chemical and Engineering News article that reported on it. Redressing that imbalance was the purpose of the current symposium entitled "Ladies in Waiting for the Nobel Prize in Chemistry. Overlooked Accomplishments of Women Chemists." This symposium, which took place in August 2017, was sponsored by the ACS History of Chemistry Division (HIST), the Women Chemists Committee (WCC), and ACS President Allison Campbell. In the Preface to The Posthumous Nobel Prize in Chemistry, Volume 1: Correcting the Errors and Oversights of the Nobel Prize, Mainz and Strom noted that "any chemist with a decent background in chemical history could readily add other deserving chemists to our list." Undoubtedly, this is also the case for the current symposium: There are other women as well as noteworthy scientists of color who could have been included. These men and women should be the topic of a future symposium. By highlighting this group of extraordinary women scientists, this book raises awareness of the Matilda effect, but more importantly, it honors them and their accomplishments.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects - properties, synthesis, reactions, physiological and industrial significance - of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Presents a comprehensive look at atmospheric corrosion, combining expertise in corrosion science and atmospheric chemistry * Is an invaluable resource for corrosion scientists, corrosion engineers, and anyone interested in the theory and application of Atmospheric Corrosion * Updates and expands topics covered to include, international exposure programs and the environmental effects of atmospheric corrosion * Covers basic principles and theory of atmospheric corrosion chemistry as well as corrosion mechanisms in controlled and uncontrolled environments * Details degradation of materials in architectural and structural applications, electronic devices, and cultural artifacts * Includes appendices with data on specific materials, experimental techniques, atmospheric species

The "greening" of industry processes, i.e. making them more sustainable, is a popular and often lucrative trend which has emerged over recent years. The 4th volume of Green Chemical Processing considers sustainable chemistry in the context of education and explores didactic approached. The American Chemical Society's 12 Principles of Green Chemistry are woven throughout this text as well as the series to which this book belongs.

This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of the volume focuses on small organic molecules with drug-like characteristics, while the second half delves into the cellular pharmacokinetics of biologics and other macromolecules, including peptide therapeutics, cyclotides, antibodies, as well as nanoparticles, thus creating a comprehensive treatise that approaches cellular pharmacokinetics from the different perspectives of pharmaceutical scientists, chemical biologists, medicinal chemists, and protein engineers dealing with very different chemical agents spanning a wide range of sizes, physicochemical properties, and targeting mechanisms. Written for the Methods in Pharmacology and Toxicology series, chapters provide the kind of key detail and expert implementation advice that leads to excellent results in the lab. Synthetic biologists, biophysicists, and bioengineers are amongst the long list of scientists who could benefit from reading this book or from using it as a textbook. Authoritative and practical, Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery builds on a long history of drug development and the adding of quantitative methods at the cellular scale in order to inspire new approaches to drug development that are better able to take advantage of phenomena such as soluble-to-insoluble phase transitions or bispecific targeting, which could ultimately be exploited for the development of more effective drug delivery systems and therapeutic agents.

Key Features: Describes feedstock evaluation and the effects of elemental, chemical and fractional composition. Details reactor types and bed types. Explores the process options and parameters involved. Assesses coke formation and additives. Considers next generation processes and developments.