Not so many years ago little attention was paid to non-parasitic respiratory diseases of cattle because they seemed of minor importance. However, in the past twenty years, as the number of cattle kept on any farm unit increased under economic pressures, there has been a concomitant rise in the prevalence of respiratory illness. Investigations into cattle respiratory diseases have become a significant part of the research effort in most countries of Europe. Initially much work went into finding, like the alchemist's stone, the orgdnism responsible for causing cattle respiratory disease. Many viruses were isolated and over the years a long list of those recovered from the respiratory tract of cattle has been prepared. Unfortunately, few of these viruses on their own are recognised as proven pathogens and no single virus provides the complete aetiological answer to bovine respiratory disease. More recently, perhaps in despair, g~eater attention has been directed to the role of mycoplasma and, additionally. a revival of interest has taken place in the significant part played by bacteria in the later stages of res piratory disease. Now, phrases such as "multifactorial disease" are being commonly used to describe the complex situation with respiratory disease.

"Endocrine-Immune Mechanisms in Animals and Human Health Implications," looks at the relationship of the hormone regulation of the immune system. His collection of articles and writings that have appeared in numerous publications explains the relationship between the endocrine and immune systems. He explains to readers how this endocrine-immune imbalance can be the cause of allergies, auto-immunity and cancer in animals and how these imbalances also apply to humans. By explaining this delicate imbalance, Plechner seeks to help his fellow health care professionals to identify the causes of certain diseases as opposed to only treating the effects of these diseases which cause specific clinical signs and symptoms. He states that there may be a reason to believe that his treatment in animals can be successful for treatment in humans also. "Over the years, I have discovered new ways to diagnose and treat the cause of many diseases and illnesses that cripple the quality of life for a patient," Plechner says. "It all stems from a hormone imbalance that leads to the disruption of the immune system." Written for fellow practitioners, biomedical researchers and pet owners, Dr. Plechner believes that readers will end this book with a new perspective on many illnesses like allergy, auto-immunity and cancer that occur in animals and in people. He hopes his research will inspire health care professionals to delve further into medical research in regards to not only treating the medical effects in animals and humans, but at the same time, identify the cause of the disease. "My hope," says the author, "is that my research will help animals and people live a better life free from disease."

This research addressed two important issues concerning conservation of orang-utans in Indonesia, the prevalence of diseases in orang-utans at reintroduction centres and the extent of intra-subspecific genetic variation between isolated populations of Bornean orang-utans. The research was conducted at the Wanariset Orang-utan Reintroduction Centre in East Kalimantan from 1994 to 1997, and at the Biomedical Primate Research Centre in the Netherlands in 1998. Studies were designed to identify and determine the prevalence of diseases, specifically gastro-intestinal parasites, tuberculosis and certain viral diseases. Further studies defined the factors associated with mortalities of orang-utans at the reintroduction centre. A molecular study using mitochondrial DNA was undertaken to determine whether there was significant genetic diversity between six isolated populations of wild orang-utans within Borneo. It was concluded that there are at least four genetically distinct populations of Bornean orang-utans. The findings of this research are discussed in terms of the implications for management policies for reintroduction centres, as well as for the conservation of wild populations.

1910. An introductory text to the study of veterinary physiology for the student and practitioner. Contents: The Blood; The Heart; The Blood vessels; Respiration; Digestion; The Liver and Pancreas; Absorption; Ductless Glands and Internal Secretions; The Skin; The Urine; Nutrition; Animal Heat; The Muscular System; The Nervous System; The Senses; The Locomotor Apparatus; The Foot; Generation and Development; Growth, Decay and Death; and The Chemical Constituents of the Body.

Aseptic arthritis of the knee joint was induced in 12 healthy donkeys, weighing 60 to 85kg by intra- articular injection of 0.3ml of turpentine oil. The animals were randomly divided into 2 groups A and B of 6 animals each. Group A served as a control whereas in Group B anti-arthritic drug, diclofenac sodium (Diclocare 5%) was administered intramuscularly at the dose rate of 2.5mg/kg body weight daily for 5-6 days starting one day after the induction of arthritis. In group B, the joint circumference became normal on 6th day after induction of arthritis while in group A (control), the joint circumference took 16 to 20 days to become normal. According to this trial, diclofenac sodium provided an early return to normal stance and weight bearing in treated group B, taking longer time in control group A. No significant change in blood Haemoglobin, Total erythrocyte count, Total leukocyte count, Erythrocyte sedimentation rate and Packed cell volume was observed in control and treated animals. It is concluded that diclofenac sodium is an effective treatment for arthritis in donkeys.

In the tradition of James Herriot, Bruce R. Coston's first book is a warm, funny, and amazingly fulfilling celebration of the wonderful world of animals as seen through the eyes of a small-town veterinarian. The patients are an eclectic and surprising cast of characters who display incredible bravery and nobility at times, and unbelievable goofiness at other times. There's the dog that resurrected itself from death. There's Daphne, the transvestite cat who taught Bruce to be a cat person. And the owners are no less engaging, ranging from the angelic to the squeamish, teaching Bruce what it really means to be an animal doctor.

Readers will gain insight into the pathos and passion, the mundane and incredible, the thigh-slapping humor and the crushing sadness of a vet's life as he seeks to mend and restore people's treasured companions. Written with great warmth, this book imparts a deeper understanding of the pets that enrich our daily lives.

The response of (laboratory) animals to anaesthetics and analgesics shows intraspecies variability. Besides environmental influences, genetic factors might be involved in this phenomenon. In the studies described in this book, rabbit and rat inbred strains were used to identify differences in response to anaesthetics and analgesics. Parameters for a genetic analysis were thus provided to identify candidate genes involved in this variability. Both in the rat and rabbit,significant strain differences were observed in the response to a variety of commonly used anaesthetics and analgesics in (laboratory animal) medicine. The difference in response to medetomidine between two rabbit strains was linked to differences in the anaesthetic's biotransformation rate. This response was then genetically analyzed and candidate genes were identified on the rabbit genetic map. In the rats it was demonstrated that buprenorphine administration did not only result in strain-specific responses to its analgesic but also to its behavioural effects. This book will aid medical and veterinary researchers in the development of tailored anaesthesia.

After leading a regional office in Africa that studied ticks and tick-borne diseases, Rupert Pegram received a call in 1994 that changed his life. His higher ups wanted him to lead a new program in the Caribbean. The Caribbean Amblyomma Program, known as the CAP, sought to eliminate the Amblyomma tick from the Caribbean region. The stakes were high because ticks transmit terrible diseases. Today, the tropical pest introduced from Africa threatens to invade large areas of the south and central parts of North America. By learning about the progress, setbacks, political and financial constraints, and final heartbreak of failure in the Caribbean, the rest of world can discover how to fight the growing problem. Learn why the CAP program failed and how the Caribbean farmers who were let down by the program suffered. This history and analysis conveys the need to re-establish vigorous research to eradicate tick-borne illnesses. Ticks are invading the larger world, and there are serious implications. They found much of their strength during Thirteen Years of Hell in Paradise.

Camels as productive animals are considered one of the primary fundamental constituents of animal population. Healthiness of this part of animal populations required healthy respiratory, urinary, skin, reproductive and musculoskeletal systems with especial attention to digestive system because camel to be productive animal needs healthy alimentary tract. The prevention of the diseases rather than treatment becomes the main aim in the veterinary medicine. Therefore, general clinical examination (temperature, pulse, respiration, mucous membranes and lymphnodes), ruminal and blood constituents were found to be the most important diagnostic and prognostic measures for health and disease conditions.

"All My Patients Have Tales" is a charming, funny, and engaging collection of stories in the great tradition of All Creatures Great and Small by the late James Herriot. Jeff Wells works in a mixed practice where he treats both farm animals and house pets, with the occasional exotic thrown in. Among the many uplifting, life-altering, life-threatening, and hilarious episodes Wells relates are stories featuring a turkey attack, porcupine-quill covered terriers, a pregnant male cat, a heavy-metal Chihuahua with road burn, an ornery pygmy donkey, a giant hog, a constipated cow, and many others.

This perfect little gem of a book will appeal to anyone who has pets, all animal lovers, and anyone who has ever toyed with the idea of becoming a vet.

Creature Comfort: Veterinary Medicine for Pet Lovers and Future Doctors.The basics of veterinary medicine for anyone who loves animals, for those who aspire to become a veterinarian, or for pet lovers who just want the inside scoop.Do you know someone who has always wanted to be a veterinarian? Is it you?Whether you´re ten years old or seventy, pet-lovers of all ages will enjoy this reader-friendly handbook on the basics of veterinary medicine. What does it take to become a veterinarian? Do I have to get straight A´s in school? How many years does it take?What do veterinarians do? What´s the difference between a small animal and a large animal veterinarian, or those who specialize in exotic animals, or reptiles, or birds, or emergency?Why do we spay and neuter? How are surgeries performed for animals? Why do they need vaccinations? Why do they need their teeth cleaned?Whether you´re planning a career in veterinary medicine or you´re just curious and you love animals, Creature Comfort: Veterinary Medicine for Pet Lovers and Future Doctors explains the basics in an engaging format with plenty of photos of our furry, four-legged friends. A portion of the proceeds from this book is donated to animal welfare organizations.

This practical manual and reference book for Veterinary and Medical students, teachers and researchers deals with diagnosis of infectious diseases. Agglutination, Precipitation,Immunoelectrophoresis, Haemagglutination, Complement Fixation, ELISA, Western Blotting, Lymphocyte Assays, Immunofluorescence, Flow Cytometry, Nucleic Acid isolation, PCR, RT-PCR, Real time PCR, gene cloning and sequencing, Avian Influenza, Rabies, Brucellosis, Plague, Anthrax, Leptospirosis, Burkholderia, Orientia and Parasitic infections, Differentiation of Infected and Vaccinated Animals in FMD and Bacteriophages are covered. Authors include Dr HV Batra, a consultant to WHO & FAO who has developed many diagnostic kits, Prof R Sharma, who heads a Reference Laboratory on FMD and has developed a DIVA kit, Dr M Rawat, who has cloned the lysin gene of a bacteriophage, Prof H M Saxena, an Immunologist, who has introduced novel modifications to enhance the sensitivity of Agglutination Test, Prof C K Singh, trained at Institut Pasteur, Paris and an expert in Rabies diagnosis, Prof Ramneek, a Virologist trained at New Zealand and Dr Debjani, a Cytometry specialist.

"After three years working as a young vet in rural Aberdeenshire, Hugh Cran decided that it was time for a change. He got it. He took a post in Kenya and, forty years later, he's still there, still working, still loving every exasperating, challenging, unexpected moment.This is a page-turning account of working as a vet at the sharp end.Cattle owned by the Maasai herdsmen or the white settlers might take up most of Hugh's time, but these cattle are assailed by lightning strike, snake bites, disease passed on by zebra and wildebeest. He's up against sun cancer, witch doctors - who knows what to expect next?Travelling miles on rough roads, Hugh never knows if he will be peforming surgery on dirty sacks, beseiged by every species of Kenyan insect, by the light of a failing car-headlamp But the colourful people who frequent Hugh's Nukuru practice, the sheer vitality of the Kenyan scene and the rewarding nature of the grinding task in hand, keep him answering that persistent phone, day and night, and heading off into the unknown."

1910. An introductory text to the study of veterinary physiology for the student and practitioner. Contents: The Blood; The Heart; The Blood vessels; Respiration; Digestion; The Liver and Pancreas; Absorption; Ductless Glands and Internal Secretions; The Skin; The Urine; Nutrition; Animal Heat; The Muscular System; The Nervous System; The Senses; The Locomotor Apparatus; The Foot; Generation and Development; Growth, Decay and Death; and The Chemical Constituents of the Body.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

Aim of this study was to select environmental E. coli isolates that produced colicins against the swine pathogen E. coli K88+. In initial evaluation using a modified plate method with 18 colicinogenic E. coli constructs, colicins E3, E4, E5, E9, Ia, K and N were found to possess inhibitory activity against 12 ETEC K88+ strains. A total of 463 environmental isolates from cattle rumen, cattle feces, pig feces and hog manure-amended soil were screened for colicin production by a modified plate test. Further, colicinogenic isolates were screened for five toxin genes LT, STa, STb, VT1 and VT2 as well as K88 (F4) fimbriae using PCR reactions. Fourteen non-pathogenic isolates were subjected to characterization of colicin genes by PCR using 9 new primer sequences, antibiotic susceptibilities and substrate utilization. Two potential probiotic strains of E. coli, UM-2 and UM-7 which produced colicins that could utilize potato starch and inulin were selected for in-vitro competition with E. coli K88+ strain 2-12. In vitro competition between the synbiotics and E. coli K88+ revealed inhibition of E. coli K88+. Animal testing of these strains is currently being undertaken.

This book includes a review of the pathophysiology of acute colitis in the adult horse and discussion of the more common etiologies for this condition and treatment options available to the equine clinician. The aim of the clinical study performed and documented was to evaluate the use of a hyperimmunized plasma containing high concentration of antibodies against Clostridium difficile, Clostridium perfringens and Salmonella sp in a referral population of equine colitis cases.Forty two horses were enrolled and 38 horses completed the study. At study admission clinical and clinicopathological parameters, other than fecal frequency score were comparable between the groups. Fecal frequency score was significantly different between the treatment groups (p=0.003). The mean duration of diarrhea was 40.79.8 hours (mean SEM), 119.256.1 hours and 72.024.5 hours for the hyperimmunized plasma, normal plasma and control groups respectively. This data confirms the hyperimmunized plasma used in this study decreased the time to resolution of diarrhea.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

Globally, dairy and beef production has become an extremely competitive industry. While the world milk production is predicted to grow significantly by 2020 with the emergence of new consumers in developing countries, milk and meat production in the more establish markets now has to fulfil new societal needs beside the simple product supply: animal health, food safety, and production environmental impact are some of them. At the same time, the recent extreme increase in feed costs emphasizes again the key role of rumen and gut efficiency management in production economics. All these new thematic topics are central to the proper management of ruminant digestive process.Producers must endeavour to seek new technologies to improve production efficiency, animal health and production costs while keeping in mind the environmental impact these changes make. "Gut Efficiency; The Key Ingredient in Ruminant Production" brings together some of the world's leading authorities in the field of ruminant nutrition and production. It considers the importance of digestive health in performance achievement together with novel strategies to manage it. It is aimed at nutritionists, veterinarians and animal producers as well as students and researchers studying animal and applied biological sciences.

This completely revised new edition is presented in three parts. Common presenting problems are considered in Part 1, using sufficient background physiology and/or anatomy of the system in a succinct way to enable the reader to understand what goes wrong with the urinary system to allow the presenting problem to occur. Differential diagnosis is considered and useful case examples illustrate the points made. Part 2 features details of how to perform and interpret both standard diagnostic techniques, such as imaging and urinalysis, and less common but very useful tests, such as staging of chronic kidney disease. More advanced techniques are also discussed to help the clinician decide when to refer cases. Part 3 deals with management of common urological syndromes, including complications and what to do if treatment fails. The emphasis is on medical management. Throughout the book, use is made of tables and flow charts as well as high-quality colour photographs.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.