Increased industrial capacity, manufacturing output, and manufacturing technology all contribute significantly to a country's GDP. Manufacturing is the foundation of industrial production, so improving its methods and infrastructure is crucial for progress. Recent years have seen the introduction of a wide range of energy- and resource-efficient, environmentally friendly, and occupationally safe manufacturing techniques, and this book focuses on these latest techniques, as well as continuous advancement, in order to meet current challenges. The book is divided into three sections: (1) subtractive manufacturing, (2) additive manufacturing, and (3) the use of artificial intelligence in manufacturing. It discusses micromaching, metal-based additive manufacturing, polymer-based additive manufacturing, hybrid additive manufacturing, and finally artificial intelligence in manufacturing. Futuristic Manufacturing: Perpetual Advancement and Research Challenges connects modern manufacturing methods and emerging trends in the industry. It adds a thorough examination of modern manufacturing techniques and modifications that may be implemented in the future, and is an excellent resource of information for undergraduate and graduate students in manufacturing.

This book, first published in 1966, reports the results of a pilot study devoted to understanding the middle-term resource situation for one metal - manganese. Two factors bring the different parts of the manganese supply-demand picture together, one economic and the other political, both of which are examined in detail in this report. Low-Grade and Nonconventional Sources of Manganese will be of interest to students of environmental studies.

This volume takes an in-depth look at various biological and chemical hazards in food and food products that pose health threats. It also outlines methods and practices for the diagnosis, prevention, and management of these hazards in food production processes. The new scientific research and case studies presented in the volume cover mycotoxins, foodborne pathogens, antibiotic residues from dairy animals, pesticide residues, the presence of heavy metals in food, and more. Chapters also address food allergy management and offer lessons and practices in food recall situations. The authors discuss the various food toxins, their sources, as well as management, mitigation, and prevention strategies. Also addressed are the specific adverse effects on people with health problems such as diabetes, hypertension, cancer, neurodegenerative diseases, and more. This book is organized in such a way that each chapter treats one major food safety hazard and offers novel control methods for health, food safety, and quality enhancement through various means. Biological and Chemical Hazards in Food and Food Products: Prevention, Practices, and Management will aid researchers and policymakers as it illustrates the various aspects of food safety hazards and how to analyze and control these potential health threats.

Authenticity Food Traceability Applied Techniques and Methods Foods of Plant Origin

In light of the rapidity increasing incidence rate of bacterial and fungal infections with multi-resistant pathogens, the metabolic changes associated with host-pathogen interactions offer one of the most promising starting points for developing novel antibiotics. . Part one of this comprehensive guide describes the metabolic adaptation of pathogenic microbes in humans, while part two points to routes for the development of novel antibiotics. This is volume six of the book series on drug discovery in infectious diseases by Paul Selzer.

Producing and Consuming the Craft Beer Movement is an ethnographic analysis of the craft beer movement and its rapid development as an industry that articulated a different set of values: celebrating, quality, community, and good taste. This book will provide an excellent foundation for considering craft beer and an entrepreneurial practice that produces other forms of value beyond monetary value. The craft beer movement has been an important movement for thinking about contemporary consumer culture, and how that consumer culture might develop a very different set of values and priorities from those of the dominant consumer culture that is created by large-scale industries focused on the instrumental values of profit and efficiency. Located in one site, the ethnography is situated within the larger context of the rise of digital media, the evolution of cities, and the latest stage of the capitalist marketplace. The book is distinctive as it is ethnographic in its methodology. It is focused on one locale, the metropolitan area around Philadelphia. Philadelphia, along with Boston, Denver, San Diego, and a few other cities, was a central location for the early development of the craft beer industry. With its interdisciplinary approach, individuals with interests in digital and social media, consumer culture, political economy, ethnography, and contemporary cultural theory will find this an interesting case study of an important industry that developed from the homebrewing movement to become an important craft industry that is now a global phenomenon. This book is directed to a broad range of readers interested in new media, consumer culture, craft, and contemporary capitalist culture. The book embeds the local in the larger historical and political economic context. Readers would include faculty members in communication, media studies, cultural studies, sociology, and anthropology. Students at a graduate and upper level undergraduate level would be interested as well.

Handbook of Thermoset Plastics, Fourth Edition provides complete coverage of the chemical processes, manufacturing techniques and design properties of each polymer, along with its applications. This new edition has been expanded to include the latest developments in the field, with new chapters on radiation curing, biological adhesives, vitrimers, and 3D printing. This detailed handbook considers the practical implications of using thermoset plastics and the relationships between processing, properties and applications, as well as analyzing the strengths and weakness of different methods and applications. The aim of the book is to help the reader to make the right decision and take the correct action on the basis of informed analysis - avoiding the pitfalls the authors' experience has uncovered. In industry, the book supports engineers, scientists, manufacturers and R&D professionals working with plastics. The information included will also be of interest to researchers and advanced students in plastics engineering, polymer chemistry, adhesives and coatings.

Discover tools to perform Life Cycle Analysis (LCA) and develop sustainable chemical technologies in this valuable guide for chemists, engineers and practitioners. Tackling one of the key challenges of modern industrial chemical engineering, this book introduces tools to assess the environmental footprint and economics of key chemical processes that make the ingredients of everyday products such as plastics, synthetic fibers, detergents and fuels. Describing diverse industrial processes in detail, it provides process flow diagrams including raw material sourcing, catalytic reactors, separation units, process equipment and recycle streams. The book clearly explains elements of LCA and how various software tools, available in the public domain and commercially, can be used to perform LCA. Supported by real-world practical examples and case studies provided by industrial and academic chemists and chemical engineers, this is an essential tool for readers involved in implementing LCA, and developing next-generation sustainable chemical technologies.

The replacement of fossil-derived compounds by bio-based fuels and chemicals is crucial for the implementation of a sustainable bioeconomy. In this context, microorganisms are key players for biofuels' production from renewable sources. Biotechnological biofuel production processes require conversion microorganisms capable of both efficiently assimilating renewable low-cost carbon sources and diverting their metabolisms towards the specific biofuel. Exploring the wide diversity of microorganisms available on Earth will surely aid to make the production of green fuels a reality. This book gives a wide overview of different microbial-based processes for green fuels production. The book also includes techno-economic analysis and highlights strategic, commercial and environmental interests in promoting green fuels. All these facts make this book very valuable not only for the scientific community but also for biofuel companies and policy makers.

Currently, change is the new normal. As change grows, so does risk. But how will leaders understand the risk if they don't measure it? In short, they won't. The reality is that ignorance is never bliss. What leaders and their organizations don't know will eventually impact them and their customers. Thus, situational awareness, forethought, and preparation are now key competencies for leaders to survive in high-risk environments. In this book, readers will learn the basics of leadership time management, the disruptability quotient, the leadership "canary" and why it's just as important to leaders as it was to coal miners, and the slippery slope of change management (do we improve, change, or model the current state?), signals of leadership maturity and false positives, mastering the art of organizational knowledge, the pearls, and pitfalls of leadership rebranding, and the risk of non-utilized talent. Why aren't current leaders required to undergo "storm proofing" from an operational perspective? As many of us experienced in various academic programs, the main foci are technical skills in management, organizational theory, data analysis, and many of the traditional leadership training courses. But, what happens when a leadership storm appears such as an unprecedented pandemic or supply chain crisis, or talent gaps where workers are not available to complete the basic services humanity relies on daily? Most leaders were not and are not prepared for today's storms. The result is reactive leadership, higher-than-expected risk propositions, and disruptive transformations that force leaders from their perches to find the next best role their skillsets will buy. This book is for leaders and professionals who are currently, or will be leading teams, divisions, and organizations. Its purpose is to provide practical guidance on how leaders can "stormproof" their portfolios. Thus, they will be able to survive, thrive in, and outlast high-risk leadership storms that will overwhelm their less-prepared peers.

The Handbook of Membrane Separations: Chemical, Pharmaceutical, Food, and Biotechnological Applications, Second Edition provides detailed information on membrane separation technologies from an international team of experts. The handbook fills an important gap in the current literature by providing a comprehensive discussion of membrane applications in the chemical, food, pharmaceutical, and biotechnology industries as well as in the treatment of toxic industrial effluents. This revised second edition has been updated and expanded with discussions of new membrane products and processes and novel applications in engineering, life sciences, and energy conversion. It also includes new chapters in the field of membrane science and technology covering recent advances in RO and UF, ionic liquids, nanotechnology, roles of membrane in power generation, updates on fuel cells, new membrane extraction configuration, and other important topics. The handbook is equally suited for the newcomer to the field as it is for process engineers and research scientists (membranologists/membrane experts) who are interested in obtaining more advanced information about specific applications. It provides readers with a comprehensive and well-balanced overview of the present state of membrane science and technology.

This handbook provides an in-depth review of information across the developmental spectrum of gene and cell therapy products. From introductory information to state-of-the-art technologies and concepts, the book provides insights into upstream processes such as vector design and construction, purification, formulation and fill/finish as well as delivery options. Planning steps for compliance with current good manufacturing practice (CGMP) to readiness for chemistry, manufacturing, and controls (CMC) are also discussed.This book wraps up with examples of successes and pitfalls addressed by experts who have navigated the multiple challenges that are part of any innovative endeavor. Features Intended as a one-stop resource for availability of state-of-the-art information related to cell and gene therapy products for researchers, scientists, management and other academic and research institutions. Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing. Discusses siRNA, mRNA, and plasmid manufacturing. Describes the importance of supplier-sponsor synergies on the path to commercialization. Diverse audience with a large number of individuals in the core technologies and supportive practices.

As the broad challenges around energy and the environment have become the focus of much research, scientists and experts have dedicated their efforts to developing more active and selective catalytic systems for key chemical transformations. For many decades environmentally viable protocols for the synthesis of fine chemicals have been the crux of academic and industrial research. Heterogeneous Catalysis in Organic Transformations serves as an overview of this work, providing a complete description of role of heterogeneous catalysis in organic transformations and offering a review of the current and near future technologies and applications. Discusses the fundamentals of catalysis and compares the advantages and disadvantages of different types of catalyst systems Examines oxide nanoparticles and noble metal nanoparticles Consider organometallic compounds, solid-supported catalysts, and mesoporous materials Describes recent advances in metal-based heterogeneous catalysts and new reactions with possible mechanistic pathways Providing a comprehensive review of heterogeneous catalysis from the basics through recent advances, this book will be of keen interest to undergraduates, graduates, and researchers in chemistry, chemical engineering, and associated fields.

Presents reasons for the supply chain disruption from various perspective and includes case studies along with an historical perspective for guidance Explores how the supply chain will take shape post COVID-19 Discusses likely future scenarios of new and emerging supply chains Describes various MCDM tools used to make complex decisions by companies to stay ahead Offers domain experts' opinions and views to help in formulating real-time strategies

Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare-i.e., personalized medicine. Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text: Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination.

In Leading Lean by Living Lean, Philip Holt details and explains what is probably the most important part of becoming a Lean Leader -- living and practicing what you preach. To do this you must believe in what you're doing, understand what it means and what you need to do, and do it every day. The author, through his engineering background, has fully embraced the Plan-Do-Check-Act (PDCA) model of Deming / Shewhart but has adapted David Bovis' Believe-Think-Feel-Act (BTFA) model to understand why logic and facts are very often not the principal players in the game of change. In this book, Holt author describes how you can take both the PDCA and BTFA models into account and has sectioned the book into three prime parts: 1. Head -- How you learn and understand the Lean principles and their application. 2. Hands -- How you practice Lean Leadership daily. 3. Heart -- How you internalize and believe in Lean Leadership. Through this book, you, the Lean practitioner, whether aspiring or experienced, will have everything that you need to "lead it," "do it," and "live it." The nature of this book is more "why to" than "how to" - the author knows that he cannot tell you how to lead, do, or live Lean; he can only explain why it is so important and share his knowledge, experiences, failures, and successes. This book isn't so much a self-help book as a self-reflection book and it can point you in the proper direction, but... the book won't change you; only you can change you! Essentially, with this book, the author wants those who think of Lean as a toolkit, who believe that Lean can be project managed, or who argue about Lean versus Six Sigma and misunderstand the fundamental depth of impact that true Lean Leadership has on an organization to be disabused of any or all of those notions. This book is aimed at those leaders who seek to experience the full transformative effects of Lean in their organizations and want to practice it at the principle level of deployment. Holt's aim is to help business leaders enhance who they are by changing what they do and the way that they do it

This new book, Advances in Energy Materials and Environment Engineering, covers the timely issue of green applications of materials. It covers the diverse usages of carbon nanotubes for energy, for power, for the protection of the environment, and for new energy applications. The diverse topics in the volume include energy saving technologies, renewable energy, clean energy development, nuclear engineering and hydrogen energy, advanced power semiconductors, power systems and energy and much more. This timely book addresses the need of the hour and will prove to be valuable for environmentally conscious industry professionals, faculty and students, and researchers in materials science, engineering, and environment with interest in energy materials.

Coaching is a necessary skill for managers. It is important as a fundamental part of an organization's talent efforts-including talent acquisition, development and retention strategies. For a coaching program to succeed in an organization, it should be recognized as a useful approach throughout the organization and become part of the fabric of the corporate culture. Performance Coaching for Managers provides an important tool for organizations to use to train their managers on coaching. This book differs significantly from other books in the coaching market. Many books on coaching cast coaches as facilitators who question their clients (the coachees), helping them to articulate their own problems, formulate their own solutions, develop their own action plans to solve problems, and measure the success of efforts to implement those plans. That is called a nondirective approach. But this book adopts a directive approach by casting the coach as a manager who diagnoses the problems with worker job performance and offers specific advice on how to solve those problems. While there is nothing wrong with a nondirective approach, it does not always work well in job performance reviews in which the manager must inform the worker about gaps between what is needed (the desired) and what is performed (the actual). The significant difference between what is currently available in the market and what is offered in this book is the authors' collective experience of over 70 combined years of hands-on research and delivery experiences in the Human Resources Development field. According to the Harvard Business Review (2015), workers generally expect their immediate supervisors to give them honest feedback on how well they do their jobs-and specific advice on what to do if they are not performing in alignment with organizational expectations. When workers do not receive advice-but instead are questioned about their own views-they regard their managers as either incompetent or disingenuous. Effective managers should be able to offer direction to their employees. After all, managers are responsible for ensuring that their organizational units deliver the results needed by the organization. If they fail to do that, the organization does not achieve its strategic goals. This book gives managers direction in how to offer directive coaching to their workers.

First volume selling primarily in the United States, push for more global promotion. "non-invasivel" related healing modalities and environmental medicine are both very hot topics. There are not any existing books with this dual focus that have an accompanying successful volume on nutrition and integrative medicine.

Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josic, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljevic Pavelic, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain

"Algae are mysterious and fascinating organisms that hold great potential for discovery and biotechnology." -Dr. Thierry Tonon, Department of Biology, University of York "Science is a beautiful gift to humanity; we should not distort it." -A.P.J. Abdul Kalam In this book, we emphasize the importance of algal biotechnology as a sustainable platform to replace the conventional fossil-based economy. With this focus, Volume 2 summarizes the up-to-date literature and knowledge and discusses the advances in algal cultivation, genetic improvement, wastewater treatment, resource recovery, commercial operation, and technoeconomic analysis of algal biotechnology. FEATURES Discusses in detail recent developments in algae cultivation and biomass harvesting Provides an overview of genetic engineering and algal-bacteria consortia to improve productivity Presents applications of algae in the area of wastewater treatment and resource recovery Provides case studies and technoeconomic analysis to understand the algal biorefinery Shashi Kant Bhatia, PhD, is an Associate Professor in the Department of Biological Engineering, Konkuk University, Seoul, South Korea. Sanjeet Mehariya, PhD, is a Postdoctoral Researcher at the Department of Chemistry, Umea University, Umea, Sweden. Obulisamy Parthiba Karthikeyan, PhD, is a Research Scientist and Lecturer (Adjunct) in the Department of Civil and Environmental Engineering, South Dakota School of Mines and Technology, Rapid City, South Dakota, USA.

Despite 40 years of aggressive pharmaceutical and surgical interventions, coronary artery disease remains the number one killer of women and men in Western civilization. Cardiovascular disease, more than ever, demonstrates the landscape has changed so significantly, that new information must be given to the young and old health professionals seeing patients on a day to day basis. Dr. Sinatra has 40 plus years of experience in cardiovascular disease and is board-certified in internal medicine and cardiology. Dr. Mark Houston practices integrative nutritional preventive cardiology and has superb expertise in hypertension, and dyslipidemia which are major factors in the genesis of cardiovascular disease. The information in this book will give doctors-to-be, and even doctors-that-are the overlooked information they need for a balanced approach to cardiovascular treatment that includes a healing/healthy diet, nutritional supplementation, exercise and weight management. Those are crucial and powerful additions to the toolbox with which to maintain health and fix problems. That's the integrative approach that Dr. Sinatra, Dr Houston and his fellow authors, have been using with great success for decades. The Table of Contents shows a true revision - all new material - this is more of a companion volume to the original edition.

This book introduces a powerful system that explains how to run a company with a focus on continuous improvement. The results are a satisfied customer base, evolving products and an increase in revenue and profits. These factors determine the success for any company because business transformation involves making fundamental changes in how business is conducted to cope with shifts in the market environment. This a comprehensive book for valuable guidance on framing strategy and overcoming challenges for successful and sustainable implementation of a lean production system, daily management system and lean accounting system in companies to empower the managers to serve their customers with timely delivery of quality products while maximizing profits and easing workloads. The main challenge is ensuring operations colleagues in different functions understand the link between their daily work and the profit and loss statement. In addition, it illustrates how finance personnel can assist the operations team and be a part of the transformation journey. This book is not meant to impart theoretical knowledge of the lean production system, daily management and lean accounting, as there are many books already available that focus on the methodology instead of the implementation. This book empowers people in each function of a company, irrespective of which level they work in the company, and shows them the way to operate on a daily basis to achieve the company's strategy while simultaneously fulfilling their career goals. The book lays out a brief history of the evolution of lean concepts with a focus on lean accounting. This book guides the successful implementation and sustenance of lean and kaizen tools and provides answers to the questions: Who should lead the lean and kaizen implementation in the company? Where should the lean and kaizen journey begin? Which lean and kaizen tools should be implemented first? How important is capacity for the company? How much current capacity is wasted and how much free capacity is available? Where exactly are the resources being wasted in the company? How can the company reduce waste to release capacity for more production? Why should the daily management system and lean accounting system be implemented simultaneously with the lean production system? Why must managers understand the monetary value of their daily activities? Is there an easy way of making a profit and loss statement that is understood at each level in the company? Why is one-day closing of accounts important and how can it be done?

In this book we present recent studies that have been carried out on some widely used medicinal plants. The need for new and alternative treatments stem from the lack of efficiency of existing remedies for certain illnesses. We have compiled information that may be useful to researchers in their quest to develop new drugs.