Modern Approaches in Drug Discovery, Volume 611, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Target Identification and Validation, Cell Painting/High Content Imaging, Target ID using chemical probes, Mining the microbiome for targets, Data driven approaches for diversity and drug-likeness, Affinity-based screening, Fragment screening (X-ray), Array-based approaches, Hit-to-lead: assessment and improvement of drug-like properties, Hit assessment and prioritization, Lead Optimization: fine tuning and risk mitigation, and more.

Corrosion Atlas: A Collection of Illustrated Case Studies, Third Edition includes 679 case histories divided over 135 materials in 13 material groups, 25 systems (installations) and 44 different phenomena. It is an essential reference work on the design, fabrication, operation and maintenance of the extremely varied and often very complicated systems and machinery used in today's technology. Case histories, with cross-references and indexes, make this book a critical resource in the solution of many corrosion problems. In addition, it brings team members closer by presenting a common language for all parties. Finally, the book serves as an important educational aid for self-study. Because of its unique, extensive, clear and beautifully produced material, the book presents a much closer link between education and the practice of corrosion prevention and control.

Hydraulic Rubber Dam: An Effective Water Management Technology is the go-to source for information on the materials, manufacture, mechanics and functional benefit of rubber dams in water management. Readers will find a detailed background on water conservation and coverage, how inflatable rubber dam technology contributes to the picture, and information on the proper manufacture and use of rubber dams to increase water storage for release and delivery during drought. In addition, the book presents tactics on the even distribution of water across populations, how to increase water use efficiency, conservation, and how to prevent flooding. In particular, this book details specialist manufacturing techniques, including the development of rubber compounds and fabric, the bonding and anchoring systems which hold the rubber dam to the underlying concrete structure, and inflation and deflation mechanisms for rubber dams. The book provides a holistic lifecycle assessment of rubber dams to give additional insight to readers looking to deploy rubber dam technology.

Analysis of Pesticide in Tea: Chromatography-Mass Spectrometry Methodology is a comprehensive book, providing serial, rapid, high-throughput analytical methods for determining more than 600 pesticides in tea. There are increasing numbers of strict limit standards for pesticide residues in edible agricultural products in countries all over the world. The threshold for pesticide residues in tea is high for international trade. At present, 17 countries and international organizations have stipulated MRL levels for over 800 pesticide residues in tea. All methods described in this book are validated by an independent, U.S.-based organization (AOAC International), and all indexes have satisfied AOAC International's criteria. China has a history of 5000 years in growing tea and is a large tea producer with 80 million people involved in tea growing. China exports tea to over 100 countries worldwide, enjoying a high reputation for quality and variety.

Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research.

Postharvest Disinfection of Fruits and Vegetables describes available technologies to reduce microbial infection for maintaining postharvest quality and safety. The book analyzes alternative and traditional methodologies and points out the significant advantages and limitations of each technique, thus facilitating both cost and time savings. This reference is for anyone in the fresh produce industry who is involved in postharvest handling and management. It discusses, in detail, the latest disinfection approaches, low-cost treatment strategies, management and protocols to control fresh produce qualities, diseases and insect infestation.

Recycling of Polyethylene Terephthalate Bottles provides an overview of PET chemistry, highlighting the main degradation, depolymerization processes and pathways of PET, along with the applications of recycled monomers derived from PET waste. The latest methodologies of recycling and feedstock recovery are covered, providing critical foundational information. In addition, the book discusses a range of established methods of polymer recycling, with an emphasis on real world industrial case studies and the latest academic research. Users will find in-depth lifecycle and cost analysis of each waste management method, comparing the suitability and feasibility of each to support the decision -making process. Polyethylene Terephthalate (PET) is the most recycled plastic in the world, but still represents a significant amount of landfill waste. This book presents an update on new regulations, providing recommendations for new opportunities in this area, including new processing methods and applications for recycled PET.

Biological Emerging Risks in Foods, Volume 86, addresses the emerging biological risks in food from a global context. Specific sections in this new release include discussions on parasites in foods as an emerging issue and antimicrobial resistance in the food chain. Specific chapters cover Norovirus: the burden of the unknown, Hepatitis E virus: a new foodborne zoonotic concern, Parasites in foods: from a neglected position to an emerging issue, Antimicrobial resistance in the food chain: an emerging global concern, Salmonella in foods: a reemerging problem, Listeria monocytogenes in foods, and Campylobacter in the food chain.

Advances in Catalysis, Volume 62, fills the gap between journal papers and textbooks across a diverse areas of catalysis research. For more than 60 years, this series has recorded and presented the latest progress in the field of catalysis, providing the scientific community with comprehensive and authoritative reviews. This series is an invaluable and comprehensive resource for chemical engineers and chemists working in the field of catalysis in both academia and industry.

Biotechnology of Metals: Principles, Recovery Methods and Environmental Concerns deals with all aspects of metal biotechnology in different areas, such as biogenesis, biomaterials, biomimetic strategies, biohydrometallurgy, mineral biobeneficiation, electrobioleaching, microbial corrosion, human implants, concrete biocorrosion, microbiology of environment pollution, and bioremediation. As the technology of this interdisciplinary science has diversified over the last five years, this book provides a valuable source for scientists and students in a number of disciplines, including geology, chemistry, metallurgy, microbiology, chemical engineering, environment, civil engineering, and biomedical engineering.

Chemical Projects Scale Up: How to Go from Laboratory to Commercial covers the chemical engineering steps necessary for taking a laboratory development into the commercial world. The book includes the problems associated with scale up, equipment sizing considerations, thermal characteristics associated with scale up, safety areas to consider, recycling considerations, operability reviews and economic viability. In addition to the process design aspects of commercializing the laboratory development, consideration is given to the utilization of a development in an existing plant.

Enzymes in Food Biotechnology: Production, Applications, and Future Prospects presents a comprehensive review of enzyme research and the potential impact of enzymes on the food sector. This valuable reference brings together novel sources and technologies regarding enzymes in food production, food processing, food preservation, food engineering and food biotechnology that are useful for researchers, professionals and students. Discussions include the process of immobilization, thermal and operational stability, increased product specificity and specific activity, enzyme engineering, implementation of high-throughput techniques, screening to relatively unexplored environments, and the development of more efficient enzymes.

Sustainable Composites for Aerospace Applications presents innovative advances in the fabrication, characterization and applications of LDH polymer nanocomposites. It covers fundamental structural and chemical knowledge and explores various properties and characterization techniques, including microscopic, spectroscopic and mechanical behaviors. Users will find a strong focus on the potential applications of LDH polymer nanocomposites, such as in energy, electronics, electromagnetic shielding, biomedical, agricultural, food packaging and water purification functions. This book provides comprehensive coverage of cutting-edge research in the field of LDH polymer nanocomposites and future applications, and is an essential read for all academics, researchers, engineers and students working in this area.

Therapeutic, Probiotic and Unconventional Foods compiles the most recent, interesting and innovative research on unconventional and therapeutic foods, highlighting their role in improving health and life quality, their implications on safety, and their industrial and economic impact. The book focuses on probiotic foods, addressing the benefits and challenges associated with probiotic and prebiotic use. It then explores the most recently investigated and well-recognized nutraceutical and medicinal foods and the food products and ingredients that have both an impact on human health and a potential therapeutic effect. The third and final section explores unconventional foods and discusses intriguing and debated foods and food sources. While research has been conducted on the beneficial biological effects of probiotics and therapeutic food, the use of these foods remains controversial. To overcome the suspicion of the use of alternative, homeopathic and traditional products as therapy, this book reveals and discusses the most recent and scientifically sound and confirmed aspects of the research.

Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It presents information on diagnoses, administration and release of therapeutics, distribution metabolism and excretion of drugs, compartmental pharmacokinetics, physiologically-based pharmacokinetics, pharmacodynamics, identifiability of models, numerical methods for models identification, design of experiments, in vitro and in vivo models, and more. As the pharma community is progressively acknowledging that a quantitative and systematic approach to drug administration, release, pharmacokinetics and pharmacodynamics is highly recommended to understand the mechanisms and effects of drugs, this book is a timely resource.

Methods in Chemical Process Safety, Volume Two, the latest release in a serial that publishes fully commissioned methods papers across the field of process safety, risk assessment, and management and loss prevention, aims to provide informative, visual and current content that appeals to both researchers and practitioners in process safety. This new release contains unique chapters on offshore safety, offshore platform safety, human factors in offshore operation, marine safety, safety during well drilling and operation, safety during processing (top side), safety during transportation of natural resources (offshore pipeline), and regulatory context

Carbon-Based Polymer Nanocomposites for Environmental and Energy Applications provides the fundamental physico-chemical characterizations of recently explored carbon-based polymer nanocomposites, such as carbon nanotubes, graphene and its derivatives, nanodiamond, fullerenes and other nano-sized carbon allotropes. The book also covers the applications of carbon-based polymer nanocomposite in the environmental and energy fields. Topics range from the various approaches that have been explored and developed for the fabrication of carbon-based polymer nanocomposite, to their applications in tackling environmental and energy related issues.

Fundamental Biomaterials: Polymers provides current information on findings and developments of biopolymers and their conversion from base materials to medical devices. Chapters analyze the types of polymers and discuss a range of biomedical applications. It is the first title in a three volume set, with each reviewing the most important and commonly used classes of biomaterials and providing comprehensive information on classification, materials properties, behavior, biocompatibility and applications. The book concludes with essential information on wear, lifetime prediction and cytotoxicity of biomaterials. This title will be of use to researchers and professionals in development stages, but will also help medical researchers understand and effectively communicate the requirements of a biomaterial for a specific application. Further, with the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for large number of students at undergraduate and post graduate levels.

Lipid Modification by Enzymes and Engineered Microbes covers the state-of-the art use of enzymes as natural biocatalysts to modify oils, also presenting how microorganisms, such as yeast, can be designed. In the past ten years, the field has made enormous progress, not only with respect to the tools developed for the development of designer enzymes, but also in the metabolic engineering of microbes, the discovery of novel enzyme activities, and in reaction engineering/process development. For the first time, these advances are covered in a single-volume that is edited by leading enzymatic scientist Uwe Borchscheuer and authored by an international team of experts.

Process Systems Engineering for Pharmaceutical Manufacturing: From Product Design to Enterprise-Wide Decisions, Volume 41, covers the following process systems engineering methods and tools for the modernization of the pharmaceutical industry: computer-aided pharmaceutical product design and pharmaceutical production processes design/synthesis; modeling and simulation of the pharmaceutical processing unit operation, integrated flowsheets and applications for design, analysis, risk assessment, sensitivity analysis, optimization, design space identification and control system design; optimal operation, control and monitoring of pharmaceutical production processes; enterprise-wide optimization and supply chain management for pharmaceutical manufacturing processes. Currently, pharmaceutical companies are going through a paradigm shift, from traditional manufacturing mode to modernized mode, built on cutting edge technology and computer-aided methods and tools. Such shifts can benefit tremendously from the application of methods and tools of process systems engineering.

Actinobacteria: Diversity and Biotechnological Applications: New and Future Developments in Microbial Biotechnology and Bioengineering, a volume in the series New and Future Developments in Microbial Biotechnology and Bioengineering series, offers the latest on the biotechnology of Kingdom actinobacteria, covering unique niches like their endosphere, rhizospheric soil and contaminated sites, etc. The book also covers the bioactive secondary metabolites obtained from actinobacteria and describes the application of microorganism (Actinobacteria) in plant growth promotion and in environmental cleanup. Finally, the book describes the biocontrol aspects of actinobacteria and how they can control fungal phytopathogens and the production of secondary metabolites.

Bridging Scales in Modelling and Simulation of Reacting Flows, Part B, Volume 53, presents key methods used to bridge scales in the simulation of reacting multiphase flows. It looks at the different aspects of such flows (transport phenomena, reactions) and includes illustrations of the methods on a variety of applications, along with the contribution of key groups in the field. Sections in this new release include multi-scale methods for fluidized bed reactors, a discussion of advances in coarse-grained discrete particle methods with industrial applications, and spatial filtering for scale bridging and its application to transport in dense bidisperse particle beds, and more.

Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Application, Volume 79, highlights the most recent LC-MS evolutions through a series of contributions by world renowned scientists that will lead the readers through the most recent innovations in the field and their possible applications. Many authoritative books on LC-MS are already present in market, describing in detail the different interfaces and their principles of operation. This book focuses more on new trends, starting with the innovations of each technique, to the most progressive challenges of LC-MS.

Nanoparticle Technology Handbook, Third Edition, is an updated and expanded authoritative reference providing both the theory behind nanoparticles and the practical applications of nanotechnology. This third edition features twenty new chapters, providing a reference much broader in scope than the previous edition. Over 140 experts in nanotechnology and/or particle technology contributed to this new edition. The book not only includes the theory behind nanoparticles, but also the practical applications of nanotechnology. It examines future possibilities and new innovations and contains important knowledge on nanoparticle characterization and the effect of nanoparticles on the environment and humans. Nanoparticle technology is a new and revolutionary technology, which is increasingly used in electronic devices and nanomaterials. It handles the preparation, processing, application and characterization of nanoparticles and has become the core of nanotechnology as an extension of conventional fine particle/powder technology. Nanoparticle technology plays an important role in the implementation of nanotechnology in many engineering and industrial fields, including electronic devices, advanced ceramics, new batteries, engineered catalysts, functional paint and ink, drug delivery system, biotechnology, etc., making use of the unique properties of nanoparticles, which are completely different from those of bulk materials.

The Alkaloids, Volume 79 is the latest in a series that has covered the topic for more than 60 years. It is considered to be the leading book series in the field of alkaloid chemistry, with more than 70 volumes that cover all aspects of alkaloids, including their chemistry, biology and pharmacology. Each release includes high-quality, timeless reviews written by renowned experts in the field, with this release focusing on pyrrolizidine alkaloids.