This issue of PET Clinics focuses on Molecular Imaging and Precision Medicine, Part II, and is edited by Dr. Rathan Subramaniam. Articles will include: Precision Medicine in Esophageal Cancer; Precision Medicine and PET/CT in Melanoma; Precision Medicine and PET/CT in Hepatobilliary and Pancreatic Cancer; Precision Medicine and PET/CT in Gastric Cancer; Precision Medicine and PET/CT in Skeletal and Soft Tissue Sarcomas; Precision Medicine and PET/MRI; Precision Medicine and PET/CT in Uterine and Ovarian Cancers; Precision Medicine and PET/CT in Cardiovascular Disorders, and more!

Radiological Imaging: The Theory of Image Formation, Detection, and Processing is intended to prepare the student to do research in radiological imaging, to teach general image science within a radiographic context, and to help the student gain fluency with the essential analytical tools of linear systems theory and the theory of stochastic processes that are applicable to any imaging system. The book contains chapters devoted to the discussion of linear systems, Poisson processes, analysis of radiographic systems, radiographic image detectors, and the various aspects of three-dimensional or tomographic imaging. Computed tomography, psychophysics, and scattered radiation and its effect on image are also elucidated. Radiology technicians will find the book very invaluable.

This book reviews the state of the art in deep learning approaches to high-performance robust disease detection, robust and accurate organ segmentation in medical image computing (radiological and pathological imaging modalities), and the construction and mining of large-scale radiology databases. It particularly focuses on the application of convolutional neural networks, and on recurrent neural networks like LSTM, using numerous practical examples to complement the theory. The book's chief features are as follows: It highlights how deep neural networks can be used to address new questions and protocols, and to tackle current challenges in medical image computing; presents a comprehensive review of the latest research and literature; and describes a range of different methods that employ deep learning for object or landmark detection tasks in 2D and 3D medical imaging. In addition, the book examines a broad selection of techniques for semantic segmentation using deep learning principles in medical imaging; introduces a novel approach to text and image deep embedding for a large-scale chest x-ray image database; and discusses how deep learning relational graphs can be used to organize a sizable collection of radiology findings from real clinical practice, allowing semantic similarity-based retrieval.The intended reader of this edited book is a professional engineer, scientist or a graduate student who is able to comprehend general concepts of image processing, computer vision and medical image analysis. They can apply computer science and mathematical principles into problem solving practices. It may be necessary to have a certain level of familiarity with a number of more advanced subjects: image formation and enhancement, image understanding, visual recognition in medical applications, statistical learning, deep neural networks, structured prediction and image segmentation.

This issue of Neuroimaging Clinics of North America focuses on Functional Connectivity, and is edited by Dr. Jay Pillai. Articles will include: Applications of rs-fMRI to presurgical mapping: sensorimotor mapping; Dynamic functional connectivity methods; Machine learning applications to rs-fMRI analysis; Frequency domain analysis of rs-fMRI; Applications of rs-fMRI to epilepsy; Data-driven analysis methods for rs-fMRI; Applications of rs-fMRI to presurgical mapping: language mapping; Limitations of rs-fMRI in the setting of focal brain lesions; Applications of rs-fMRI to neuropsychiatric disease; Applications of rs-fMRI to Traumatic Brain Injury; Applications of rs-fMRI to neurodegenerative disease; Graph theoretic analysis of rs-fMRI; and more!

Volume 22, entitled Metal Ions in Bio-Imaging Techniques, of the series Metal Ions in Life Sciences deals with metal ions as tools in imaging. This dates back to the first half of the past century, when barium sulfate was orally given to patients undergoing X-ray examination. The use of contrast agents has since developed into a large interdisciplinary field encompassing not only medicine, but also chemistry, material sciences, physics, biology, engineering, and computer sciences. MILS-22 provides deep and current insights in 17 stimulating chapters on the new research frontiers of this fast growing field on bio-imaging ... and beyond. For example, adding bio-sensing yields theranostic agents, meaning diagnosis and therapy linked in the same molecule; ions of Gd, Mn, Fe, Co, Ir, 99mTc, etc., are involved. Other important topics are, e.g., metal complexes in paramagnetic Chemical Exchange Transfer (paraCEST), radiometals for Positron Emission Tomography (PET) imaging, or paramagnetic metal ion probes for 19F magnetic resonance imaging. MILS-22 is written by 57 internationally recognized experts from 12 countries, that is, from the US via Europe to China. The impact of this vibrant research area is manifested by more than 2300 references and nearly 120 figures, mostly in color, and several informative tables. To conclude, Metal Ions in Bio-Imaging Techniques is an essential resource for scientists working in the wide range from material sciences, enzymology, analytic, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that also excellent information for teaching is provided.

This volume covers state-of-the-art applications of solid-state and solution nuclear magnetic resonance( NMR) spectroscopy to study protein structure, dynamics and interactions. Chapters detail various aspects of data acquisition and processing, determination of the structure, multi-timescale dynamics of entities ranging from individual proteins to large macromolecular complexes to intact viral assemblies. The final two chapters will highlight the promise of NMR beyond field strengths of 1 GHz to study the structure, dynamics and interactions of a larger class of proteins and protein complexes of extraordinary biological interest. Written in the highly successful Methods in Molecular Biology series format, chapters provide detailed laboratory protocols and troubleshooting tips that would be of great practical help to NMR spectroscopists with different levels of expertise. Authoritative and cutting-edge, Protein NMR: Methods and Protocol aims to ensure successful results in the further study of this vital field.

This new book reviews the legal, ethical, risk management and safety issues facing today's radiological science professional. It discusses theories and their day-to-day application, guiding good decision making. Case studies and scenarios clearly illustrate concepts. Sample forms at the end of the text help readers prepare and draft forms, charts, procedures, and policies.Covers a full range of issues - decision making, malpractice, patients' rights, civil liability, record keeping, communication, education, and much more. Clarifies the importance of risk management and the need for developing a quality safety program to protect the patient, the practitioner, and the facility.Considers the practical applications of the Code of Ethics. Answers key questions about employment law.Presents specific plans for setting up education and evaluation programs. Includes sample forms for assessing competency. Provides an overview of the legal system and how it affects imaging and therapy.Offers two complete chapters that explain what and how to document. Includes sample forms for documentation and consent. Readers can simply review and adapt to their own health care settings.Features contributions by professionals with special expertise in law, risk management and education.

Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging provides a complete review of computer methods for atherosclerotic plaque reconstruction and characterization. The authors, with their expertise from biomedical engineering, computer science, and cardiology, offer a holistic view. The focus of the book is on the presentation of major imaging techniques, including their limitations. It includes details on the mechanical characterization and properties of plaques and appropriate constitutive models to describe the mechanical behavior of plaques. The authors explore the challenges of using multiple coronary imaging technologies, and provide the pros and cons of invasive vs. non-invasive techniques. Methods for plaque characterization and 3D reconstruction of coronary arteries using IVUS, OCT, and CT images are described. This book will help readers study new trends in image processing analysis and plaque characterization, implement automated plaque characterization methodologies, understand coronary imaging drawbacks, and comprehend 3 dimensional coronary artery and plaque reconstruction methods.

This issue of Radiologic Clinics of North America focuses on Skull Base Imaging, and is edited by Dr. Nafi Aygun. Articles will include: Overview of Expanded Endonasal Approaches to the Skull Base for Radiologists; Imaging of Paranasal Sinuses and Anterior Skull Base; Imaging of the Sella Turcica and Pituitary Gland; Imaging of Diplopia; Imaging of the Central Skull Base; Imaging of Vascular Compression Syndromes (Including Trigeminal Neuralgia and Hemifacial Spasm); Imaging of the Posterior Skull Base (Lower Cranial Nerves Excluding the 7th and 8th Nerves); Imaging Evaluation and Treatment of Vascular Lesions at the Skull Base; Perineural Spread of Tumor in the Skull Base; Advanced Imaging Techniques of the Skull Base; High Resolution Imaging of the Skull Base; Imaging of Cerebrospinal Fluid Rhinorrhea and Otorrhea, and more!

This issue of Radiologic Clinics of North America focuses on Practical Pediatric Imaging, and is edited by Dr. Edward Lee. Articles will include: Practical Imaging Approach to Traumatic Brain Injuries in Children; Pediatric Thoracic Normal Variants: What Should Radiologists Need to Know?; Respiratory Distress in Neonates: Underlying Etiologies and Imaging Assessment; Child with Cough and Fever: Up to Date Imaging Evaluation and Management; Thoracic Neoplasms in Children: Contemporary Perspectives and Imaging Assessment; Cardiovascular Malformations in Children: Current Indications, Techniques, and Imaging Findings; Neonatal Gastrointestinal Emergencies: Step-by-Step Approach; Pediatric Abdominal Neoplasms: An Overview and Update; Musculoskeletal Traumatic Injuries in Children: Characteristic Imaging Findings; Practical Imaging Evaluation of Foreign Bodies in Children: What Is New?; Syndromic Disorders Associated with Pediatric Tumors: Spectrum of Diseases and Imaging Findings; Practical Indication-Based Pediatric Nuclear Medicine Studies: Update and Review; and more!

This issue of Radiologic Clinics of North America focuses on Breast Imaging, and is edited by Dr. Sarah M. Friedewald. Articles will include: Evidence to Support Screening Women in Their 40s; Evidence to Support Screening Women Annually; High Risk Screening and Use of Risk Assessment Models; Breast Tomosynthesis: Clinical Evidence; Breast Tomosynthesis: Practical Considerations; Synthesized Digital Mammography Imaging; Breast Density Legislation and Clinical Evidence; Whole Breast Screening Ultrasound Implemenation; Breast MRI in the Newly Diagnosed Breast Cancer Patient; MRI: Future Imaging Techniques; Breast PET-MR; Update on Pre-Operative Needle Localization Techniques, and more!

This books brings together multi-disciplinary expertise to provide comprehensive information about molecular imaging of infectious diseases. Also described are the development of new imaging technologies for infectious disease and their translation to the clinic. The overall goal of Imaging Infections: From Bench to Bedside is to spur interest and innovation in this emerging field. We anticipate that these technologies will not only allow unique insights into understanding pathogenesis of infections but also expedite bench-to-bedside translation of new therapeutics. While molecular imaging is already in common use in the clinic, this book demonstrates how it could also become a valuable tool for clinical studies, patient care, public health, and for enabling precision medicine for infectious diseases.

This book presents a comprehensive, state-of the-art guide and review of ultrasound applications for children and infants with surgical problems. It is meant as a single source to provide information about sonographic application, interpretation and technique for a diversity of pediatric surgical care providers, making it a useful tool for the ultrasound novice as well as the more advanced ultrasonographer. Sections address initial obstacles faced by a physician starting with ultrasound such as the scanning techniques, underlying anatomy and normal sonographic findings. The initial chapter provides an introduction and basic overview about ultrasound theory and techniques. Subsequent chapters focus on specific body parts and systems and their disease processes as it pertains to pediatric and neonatal patients. The text also includes a chapter on abdominal trauma and its evaluation with the FAST (focused abdominal sonography for trauma) exam. Diagnostic and Interventional Ultrasound in Pediatric Surgery serves as a useful resource for a broad spectrum of pediatric care providers, including a growing number of ultrasound users, surgeons and pediatricians alike.

This issue of Radiologic Clinics of North America focuses on Imaging of the Athlete, and is edited by Drs. Adam Zoga and Johannes Roedl. Articles will include: The Thrower's Shoulder; Multimodality Imaging and Imaging Guided Therapy for the Painful Elbow; The Skeletally Immature and Newly Mature Throwing Athlete; Imaging Throwing Injuries Beyond the Shoulder and Elbow; Imaging Adductor Injury and "The Inguinal Disruption"; Image Guided Core Intervention and Postop Imaging; Core Injuries Remote from the Pubic Symphysis; MRI and MR Arthrography of the Hip; Knee Meniscus Biomechanics and Microinstability; Imaging Turf Toe and Traumatic Forefoot Injury; Imaging the Postoperative Knee; The Hindfoot Arch: What Role does the Imager Play?; Using Imaging to Determine Return to Play; and more!

The only review book of its kind, David M. Yousem's Non-Interpretive Skills prepares you for exam questions on every aspect of radiology that does not involve reading and interpreting images: communication, quality and safety, ethics, leadership, data management, business principles, analytics, statistics, and more. Ideal for residents and practitioners alike, this unique study tool contains hundreds of questions, answers, and rationales that cover the entire range of NIS content on the credentialing boards and MOC exams. Your exam preparation isn't complete without it! Exclusive test preparation on every NIS area, including business, ethics, safety, quality improvement, resuscitation techniques, and medications used by radiologists. 600 multiple-choice questions with answers and rationales provide a practical and solid foundation for exams and clinical practice. Author David M. Yousem, MD, MBA and his colleagues at the Johns Hopkins Department of Radiology share years of expertise in radiology education, quality assurance, and business topics. A single, easy-to-use source for thorough review of the NIS topics you'll encounter on exams and in your radiology practice. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

This issue of Neuroimaging Clinics of North America focuses on Adult Brain Tumors, and is edited by Dr. Lara Brandao. Articles will include: Posterior Fossa Tumors in Adult Patients; Lymphomas and Adult Brain Tumors; Pre-Treatment Evaluation of Gliomas; Post Treatment Evaluation of Gliomas; Metastasis in Adult Brain Tumors; Extraparenchymal Lesions in Adult Brain Tumors; Interesting Case Studies in Adult Brain Tumors; Advanced MR Imaging Techniques in Daily Practice; and more!

This issue of Hematology/Oncology Clinics of North America is devoted to Imaging of Neurological complications in Hematological disorders and will include articles on Blood Dyscriasis: Classification and Clinical Neurological Presentations, Imaging Manifestation of Anemia, CNS Complications of Hemorrhagic and Coagulation Disorders, Neurological and Head and Neck Manifestation of Sickle Cell Disease, Neuroimaging in Lymphoma, and many more!

This issue of Radiologic Clinics of North America focuses on Extranodal Lymphoma from Head to Toe, and is edited by Dr. Mark Murphey. Articles will include: Pathology of Extranodal Lymphoma; Pulmonary and Mediastinal Extranodal Lymphoma; Gastrointestinal Extranodal Lymphoma; Extranodal Lymphoma Involving the CNS and Spine; Genitourinary Extranodal Lymphoma; Musculoskeletal Extranodal Lymphoma; Pediatric Extranodal Lymphoma; Extranodal Lymphoma of the Breast; Cardiac Extranodal Lymphoma, and more!

This issue of MRI Clinics of North America focuses on MR in the Emergency Room. Articles will include: MR Imaging of Stroke; MR Imaging of Acute Head and Neck Infections; Use of MR in the Evaluation of Cranial Trauma; MR of Spinal Emergencies; Emergency MR Imaging of Musculoskeletal Trauma; Use of MR in Non-traumatic Musculoskeletal Emergencies; MR Imaging of Abdominal Pain in Pregnancy; MR of Pelvic and Gastrointestinal Emergencies; Use of MR in Pediatric Emergencies; Use of MR in Pancreatico-Biliary Emergencies; and more!

This issue of Radiologic Clinics of North America focuses on Imaging of Selected Multi-System Disorders. Articles will include: von Hippel-Lindau syndrome: Review of Genetics and Imaging; Cross-sectional Imaging Review of Tuberous Sclerosis; Multiple Endocrine Neoplasia Syndromes: A Comprehensive Imaging Review; Imaging Manifestations of Thoracic Tuberculosis; Imaging Spectrum of Extra-Thoracic Tuberculosis; MDCT and MRI Findings of Mycotic Infections; Imaging of Sarcoidosis: A Contemporary Review; Imaging of Inflammatory Myofibroblastic Tumor; Recent Advances in Imaging of IgG4-related Disease; Systemic Vasculopathy Syndromes: Overview of Imaging & Management; Taxonomy and Imaging Manifestations of Systemic Amyloidosis; State of the Art Imaging & Staging of Multiple Myeloma & Plasmacytoma; Solitary Fibrous Tumor: 2016 Imaging Update; and more!

This issue of PET Clinics focuses on PET-Based Molecular Imaging in Evolving Personalized Management Design, and is edited by Drs. Abass Alavi and Sandip Basu. Articles will include: PET-Based Personalized Medicine: An Unavoidable Path for the Foreseeable Future; Personalized Management Approaches in Lymphoma: Help from PET; PET-CT in Head-Neck Malignancies: the Implications for Personalized Clinical Practice; PET Imaging of Skeletal Metastases and its Role in Personalising Further Management; PET-Based Molecular Imaging in Designing a Personalized Management Model in Neuroendocrine Tumors; Personalized Clinical Decision Making in GI Malignancies: Where Can PET Help?; PET in Breast Carcinoma: Can it Aid in Developing a Personalized Treatment Design; PET and Thyroid Cancer: Can it Help in Evolving a Personalized Treatment Design?; PET Imaging Towards Individualized Management of Urological and Gynaecological Malignancies; The Possible Role of PET Imaging towards Individualized Management of Bone and Soft Tissue Malignancies; PET-Based Personalized Management of Inflammatory Disorders; PET-Based Radiation Oncology; PET-Based Interventional Radiology; The Current and Evolving Role of PET in Personalized Management of Lung Carcinoma, and more!

There are more than 63,000 new cases of uterine and endometrial cancer each year in the United States, up from approximately 41,000 when the first edition of Uterine Cancer was published in 2009. A book focusing on these cancers was timely, with emergent sophistication in diagnosis increasingly impacting clinical decision-making. However, five years later, the need for an updated book on this topic is even stronger as oncologists recognize opportunities to impact the outcome on women that are increasingly diagnosed with these malignancies. Uterine Cancer: Screening, Diagnosis, and Treatment, Second Edition, part of the Current Clinical Oncology series, enhances the awareness on this somewhat neglected area of therapeutics, helping to integrate targeted therapies into the management of women with uterine cancer. Written by experts in the field in a highly practical and comprehensive manner, it is a must-have for all gynecological residents and fellows, as well as gynecological oncologists, medical oncologists, radiation oncologists, and family practice doctors who wish to provide their patients with the best possible care.

This book presents new methods of analyzing and processing hyperspectral medical images, which can be used in diagnostics, for example for dermatological images. The algorithms proposed are fully automatic and the results obtained are fully reproducible. Their operation was tested on a set of several thousands of hyperspectral images and they were implemented in Matlab. The presented source code can be used without licensing restrictions. This is a valuable resource for computer scientists, bioengineers, doctoral students, and dermatologists interested in contemporary analysis methods.

This issue of Radiologic Clinics of North America focuses on CT Angiography. Articles will include: CT Angiography - A Review and Technical Update; CT Angiography of Thoracic Aorta; CT Angiography of Abdominal Aorta; CT Angiography of the Liver, Spleen, and Pancreas; CT Angiography of the Bowel and Mesentery; CT Angiography of the Renal Circulation; CT Angiography of the Lower Extremities; CT Angiography of the Upper Extremities; Pediatric Considerations in CT Angiography; CT Angiography of the Neurovascular Circulation; Role of MRA in the Era of Modern CT Angiography; CT Angiography for Preoperative Thoracoabdominal Flap Planning; and more!

Imaging of Paranasal Sinuses is explored in this important Neuroimaging Clinics issue. Articles include: Current trends in sinonasal imaging; Normal anatomy and anatomic variants of the paranasal sinuses on CT; Pre-treatment imaging in inflammatory sinonasal disease; The role of CT and MRI in imaging of fungal sinusitis; Imaging approach to sinonasal tumors; The role of CT and MRI in imaging of sino-nasal tumors; The role of CT and MRI in the skull base in evaluation of sino-nasal disease; Post-treatment imaging of the paranasal sinuses following endoscopic sinus surgery; Post-treatment imaging of the paranasal sinuses following treatment for sinonasal neoplasia; and more!