This issue of Radiologic Clinics of North America focuses on Practical Pediatric Imaging, and is edited by Dr. Edward Lee. Articles will include: Practical Imaging Approach to Traumatic Brain Injuries in Children; Pediatric Thoracic Normal Variants: What Should Radiologists Need to Know?; Respiratory Distress in Neonates: Underlying Etiologies and Imaging Assessment; Child with Cough and Fever: Up to Date Imaging Evaluation and Management; Thoracic Neoplasms in Children: Contemporary Perspectives and Imaging Assessment; Cardiovascular Malformations in Children: Current Indications, Techniques, and Imaging Findings; Neonatal Gastrointestinal Emergencies: Step-by-Step Approach; Pediatric Abdominal Neoplasms: An Overview and Update; Musculoskeletal Traumatic Injuries in Children: Characteristic Imaging Findings; Practical Imaging Evaluation of Foreign Bodies in Children: What Is New?; Syndromic Disorders Associated with Pediatric Tumors: Spectrum of Diseases and Imaging Findings; Practical Indication-Based Pediatric Nuclear Medicine Studies: Update and Review; and more!

Radiological Imaging: The Theory of Image Formation, Detection, and Processing is intended to prepare the student to do research in radiological imaging, to teach general image science within a radiographic context, and to help the student gain fluency with the essential analytical tools of linear systems theory and the theory of stochastic processes that are applicable to any imaging system. The book contains chapters devoted to the discussion of linear systems, Poisson processes, analysis of radiographic systems, radiographic image detectors, and the various aspects of three-dimensional or tomographic imaging. Computed tomography, psychophysics, and scattered radiation and its effect on image are also elucidated. Radiology technicians will find the book very invaluable.

This issue of Radiologic Clinics of North America focuses on Breast Imaging, and is edited by Dr. Sarah M. Friedewald. Articles will include: Evidence to Support Screening Women in Their 40s; Evidence to Support Screening Women Annually; High Risk Screening and Use of Risk Assessment Models; Breast Tomosynthesis: Clinical Evidence; Breast Tomosynthesis: Practical Considerations; Synthesized Digital Mammography Imaging; Breast Density Legislation and Clinical Evidence; Whole Breast Screening Ultrasound Implemenation; Breast MRI in the Newly Diagnosed Breast Cancer Patient; MRI: Future Imaging Techniques; Breast PET-MR; Update on Pre-Operative Needle Localization Techniques, and more!

This books brings together multi-disciplinary expertise to provide comprehensive information about molecular imaging of infectious diseases. Also described are the development of new imaging technologies for infectious disease and their translation to the clinic. The overall goal of Imaging Infections: From Bench to Bedside is to spur interest and innovation in this emerging field. We anticipate that these technologies will not only allow unique insights into understanding pathogenesis of infections but also expedite bench-to-bedside translation of new therapeutics. While molecular imaging is already in common use in the clinic, this book demonstrates how it could also become a valuable tool for clinical studies, patient care, public health, and for enabling precision medicine for infectious diseases.

Modern life is increasingly relying on digital technology, which in turn runs on mathematics. However, this underlying math is hidden from us. That is mostly a good thing since we do not want to be solving equations and calculating fractions just to get things done in our everyday business. But the mathematical details do matter for anyone who wants to understand how stuff works, or wishes to create something new in the jungle of apps and algorithms. This book takes a look at the mathematical models behind weather forecasting, climate change prediction, artificial intelligence, medical imaging and computer graphics. The reader is expected to have only a curious mind; technical math skills are not needed for enjoying this text.

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies.The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. Novel biomedical applications have been included, where appropriate. All the chapters have been thoroughly reworked and the artwork updated.

This volume covers state-of-the-art applications of solid-state and solution nuclear magnetic resonance( NMR) spectroscopy to study protein structure, dynamics and interactions. Chapters detail various aspects of data acquisition and processing, determination of the structure, multi-timescale dynamics of entities ranging from individual proteins to large macromolecular complexes to intact viral assemblies. The final two chapters will highlight the promise of NMR beyond field strengths of 1 GHz to study the structure, dynamics and interactions of a larger class of proteins and protein complexes of extraordinary biological interest. Written in the highly successful Methods in Molecular Biology series format, chapters provide detailed laboratory protocols and troubleshooting tips that would be of great practical help to NMR spectroscopists with different levels of expertise. Authoritative and cutting-edge, Protein NMR: Methods and Protocol aims to ensure successful results in the further study of this vital field.

This new book reviews the legal, ethical, risk management and safety issues facing today's radiological science professional. It discusses theories and their day-to-day application, guiding good decision making. Case studies and scenarios clearly illustrate concepts. Sample forms at the end of the text help readers prepare and draft forms, charts, procedures, and policies.Covers a full range of issues - decision making, malpractice, patients' rights, civil liability, record keeping, communication, education, and much more. Clarifies the importance of risk management and the need for developing a quality safety program to protect the patient, the practitioner, and the facility.Considers the practical applications of the Code of Ethics. Answers key questions about employment law.Presents specific plans for setting up education and evaluation programs. Includes sample forms for assessing competency. Provides an overview of the legal system and how it affects imaging and therapy.Offers two complete chapters that explain what and how to document. Includes sample forms for documentation and consent. Readers can simply review and adapt to their own health care settings.Features contributions by professionals with special expertise in law, risk management and education.

This book presents different approaches on multi-modality imaging with a focus on biomedical applications. Medical imaging can be divided into two categories: functional (related to physiological body measurements) and anatomical (structural) imaging modalities. In particular, this book covers imaging combinations coming from the usual popular modalities (such as the anatomical modalities, e.g. X-ray, CT and MRI), and it also includes some promising and new imaging modalities that are still being developed and improved (such as infrared thermography (IRT) and photoplethysmography imaging (PPGI)), implying potential approaches for innovative biomedical applications. Moreover, this book includes a variety of tools on computer vision, imaging processing, and computer graphics, which led to the generation and visualization of 3D models, making the most recent advances in this area possible. This is an ideal book for students and biomedical engineering researchers covering the biomedical imaging field.

This issue of Radiologic Clinics of North America focuses on Skull Base Imaging, and is edited by Dr. Nafi Aygun. Articles will include: Overview of Expanded Endonasal Approaches to the Skull Base for Radiologists; Imaging of Paranasal Sinuses and Anterior Skull Base; Imaging of the Sella Turcica and Pituitary Gland; Imaging of Diplopia; Imaging of the Central Skull Base; Imaging of Vascular Compression Syndromes (Including Trigeminal Neuralgia and Hemifacial Spasm); Imaging of the Posterior Skull Base (Lower Cranial Nerves Excluding the 7th and 8th Nerves); Imaging Evaluation and Treatment of Vascular Lesions at the Skull Base; Perineural Spread of Tumor in the Skull Base; Advanced Imaging Techniques of the Skull Base; High Resolution Imaging of the Skull Base; Imaging of Cerebrospinal Fluid Rhinorrhea and Otorrhea, and more!

This manual is a comprehensive guide to radiological imaging for the diagnosis of diseases and disorders in children. The fourth edition has been fully revised and features many new topics, providing the latest advances in the field. Divided into 35 chapters, the book covers all the main imaging modalities - CT, MRI, ultrasound and digital radiography, and their use in the diagnosis of disorders in different body systems. Numerous radiological images, tables and boxes further enhance the extensive text. Key points Comprehensive guide to radiological imaging in children Fully revised, fourth edition, featuring many new topics and latest advances Covers all the main imaging modalities accompanied by radiological photographs, tables and boxes Previous edition (9789350252055) published in 2011

This issue of Neuroimaging Clinics of North America focuses on Adult Brain Tumors, and is edited by Dr. Lara Brandao. Articles will include: Posterior Fossa Tumors in Adult Patients; Lymphomas and Adult Brain Tumors; Pre-Treatment Evaluation of Gliomas; Post Treatment Evaluation of Gliomas; Metastasis in Adult Brain Tumors; Extraparenchymal Lesions in Adult Brain Tumors; Interesting Case Studies in Adult Brain Tumors; Advanced MR Imaging Techniques in Daily Practice; and more!

This issue of Radiologic Clinics of North America focuses on Imaging of the Athlete, and is edited by Drs. Adam Zoga and Johannes Roedl. Articles will include: The Thrower's Shoulder; Multimodality Imaging and Imaging Guided Therapy for the Painful Elbow; The Skeletally Immature and Newly Mature Throwing Athlete; Imaging Throwing Injuries Beyond the Shoulder and Elbow; Imaging Adductor Injury and "The Inguinal Disruption"; Image Guided Core Intervention and Postop Imaging; Core Injuries Remote from the Pubic Symphysis; MRI and MR Arthrography of the Hip; Knee Meniscus Biomechanics and Microinstability; Imaging Turf Toe and Traumatic Forefoot Injury; Imaging the Postoperative Knee; The Hindfoot Arch: What Role does the Imager Play?; Using Imaging to Determine Return to Play; and more!

The field of inflammatory bowel disease has evolved in many ways. The first has been the revolution in medical therapy for the disease. With the advent of biologic therapy, the aspirational goal of therapy has become mucosal healing. These medications have also made it possible to avoid or delay surgery for ulcerative colitis and Crohn's disease. Although non-invasive strategies such as MR or CT enterography or stool-based assays are helpful, they have not been able to replace the prognostic information provided by endoscopy. Simultaneously, the quality and spectrum of tools available to perform endoscopy has widened. High resolution endoscopes are now the norm and are nearly as good as chromoendoscopy for identifying dysplasia in ulcerative colitis patients. Most gastroenterologists also perform dilations but do not generally do this for patients with IBD. Finally, newer devices such as enteroscopes, endoscopic ultrasound, and endomicroscopes are being incorporated into the algorithms to diagnose and treat complications of IBD. This issue highlights all of these advances by the experts in their fields.

This issue of Radiologic Clinics of North America focuses on Diffuse Lung Disease, and is edited by Dr. Jeffrey Kanne. Articles will include: Idiopathic Interstitial Pneumonias: An Update; Collagen-Vascular Diseases; Hypersensitivity Pneumonitis; Acute Lung Injury; Occupational Lung Diseases; Pulmonary Vasculitis; Eosinophilic Lung Diseases; Large Airways Diseases; Small Airways Diseases; Smoking Related Lung Diseases; Pulmonary Hypertension; and more!

The only review book of its kind, David M. Yousem's Non-Interpretive Skills prepares you for exam questions on every aspect of radiology that does not involve reading and interpreting images: communication, quality and safety, ethics, leadership, data management, business principles, analytics, statistics, and more. Ideal for residents and practitioners alike, this unique study tool contains hundreds of questions, answers, and rationales that cover the entire range of NIS content on the credentialing boards and MOC exams. Your exam preparation isn't complete without it! Exclusive test preparation on every NIS area, including business, ethics, safety, quality improvement, resuscitation techniques, and medications used by radiologists. 600 multiple-choice questions with answers and rationales provide a practical and solid foundation for exams and clinical practice. Author David M. Yousem, MD, MBA and his colleagues at the Johns Hopkins Department of Radiology share years of expertise in radiology education, quality assurance, and business topics. A single, easy-to-use source for thorough review of the NIS topics you'll encounter on exams and in your radiology practice. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

This book presents new methods of analyzing and processing hyperspectral medical images, which can be used in diagnostics, for example for dermatological images. The algorithms proposed are fully automatic and the results obtained are fully reproducible. Their operation was tested on a set of several thousands of hyperspectral images and they were implemented in Matlab. The presented source code can be used without licensing restrictions. This is a valuable resource for computer scientists, bioengineers, doctoral students, and dermatologists interested in contemporary analysis methods.

This book presents a comprehensive, state-of the-art guide and review of ultrasound applications for children and infants with surgical problems. It is meant as a single source to provide information about sonographic application, interpretation and technique for a diversity of pediatric surgical care providers, making it a useful tool for the ultrasound novice as well as the more advanced ultrasonographer. Sections address initial obstacles faced by a physician starting with ultrasound such as the scanning techniques, underlying anatomy and normal sonographic findings. The initial chapter provides an introduction and basic overview about ultrasound theory and techniques. Subsequent chapters focus on specific body parts and systems and their disease processes as it pertains to pediatric and neonatal patients. The text also includes a chapter on abdominal trauma and its evaluation with the FAST (focused abdominal sonography for trauma) exam. Diagnostic and Interventional Ultrasound in Pediatric Surgery serves as a useful resource for a broad spectrum of pediatric care providers, including a growing number of ultrasound users, surgeons and pediatricians alike.

This book talks about photoplethysmography (PPG) techniques based on computer-aided data processing. In particular, it presents the results of a co-operative Indo-German project on the topic between Indian Institute of Technology at Chennai and RWTH Aachen University. Measuring system design, experimental details and some preliminary results obtained so far within the framework of this project are presented here. From the investigations carried out so far using the PPG sensors in conjunction with breathing sensors, it has been possible to monitor the 0.125 to 0.15 Hz rhythms in the arterial volumetric changes and to study the influence of breathing on them. These rhythms, which according to medical experts have relevance to psychosomatic conditions e.g. stress or relaxation, can also be addressed to by ancient Indian practices like yoga and meditation. This book presents the results of studying the effects of Indian relaxation techniques like pranayama, meditation, etc. in comparison to western relaxation techniques like autogenic training. So far it has been established that the Indian techniques of relaxation like yoga and meditation are very effective in generating low frequency rhythms in the skin perfusion as monitored by optical sensors. According to medical experts, these low frequency rhythms have a very important bearing on the human physiology and have potential therapeutic implications. This book is meant to provide an overview of the current state-of-knowledge and encourage the next generation of scientists/engineers to carry this work forward, especially on the novel PPG application fields that are of growing importance like pain and stress assessment, detection of peripheral venous saturation and local arterio-venous oxygen consumption as well as contactless space resolved skin perfusion studies with modern camera based PPG technology.

The Migraine Brain, edited by David Borsook, Arne May, Peter J. Goadsby, and Richard Hargreaves, makes a major contribution to the field, addressing the increasingly sophisticated neuroimaging techniques that have allowed researchers to begin to define functional and anatomical characteristics of migraine and other less-common types of headache. Of particular focus is how imaging is changing the way we understand migraine. This includes changes in function, structure and chemistry of the migraine brain. Included are sections that focus on particular aspects of migraine, for example the migraine aura: those symptoms that cause visual sensitivity (blinding white light), sensory difficulty (loud noises, painful touch, and hot/cold spells), slurred language, and motor dysfunction.
Extensively illustrated throughout, The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches.
A collation of the top thinkers in the field and the only book of its kind, The Migraine Brain is necessary reading for neurologists and neuroscientists.

This issue of Hematology/Oncology Clinics of North America is devoted to Imaging of Neurological complications in Hematological disorders and will include articles on Blood Dyscriasis: Classification and Clinical Neurological Presentations, Imaging Manifestation of Anemia, CNS Complications of Hemorrhagic and Coagulation Disorders, Neurological and Head and Neck Manifestation of Sickle Cell Disease, Neuroimaging in Lymphoma, and many more!

This issue of MRI Clinics of North America focuses on MR Imaging of the Spine, and is edited by Dr. Mario Muto. Articles will include: Diagnostic Approach to Pediatric Spin Pathology; Neuroimaging of Scoliosis and Sagittal Balance; Neuroimaging of the Degenerative Spine; Neuroimaging of Spinal Instability; Neuroimaging of the Traumatic Spine; Neuroimaging of Spine Infections; Neuroimaging of the Post Operative Spine; Neuroimaging of Spinal Canal Stenosis; Neuroimaging of Spinal Tumors, and more!

Neuroimaging, Part Two, a volume in The Handbook of Clinical Neurology series, illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This second volume covers imaging of the adult spine and peripheral nervous system, as well as pediatric neuroimaging. In addition, it provides an overview of the differential diagnosis of the most common imaging findings, such as ring enhancement on MRI, and a review of the indications for imaging in the most frequent neurological syndromes. The volume concludes with a review of neuroimaging in experimental animals and how it relates to neuropathology. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, with the entire field moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to the new horizon in the study of neurological disorders.

This issue of PET Clinics focuses on PET-Based Molecular Imaging in Evolving Personalized Management Design, and is edited by Drs. Abass Alavi and Sandip Basu. Articles will include: PET-Based Personalized Medicine: An Unavoidable Path for the Foreseeable Future; Personalized Management Approaches in Lymphoma: Help from PET; PET-CT in Head-Neck Malignancies: the Implications for Personalized Clinical Practice; PET Imaging of Skeletal Metastases and its Role in Personalising Further Management; PET-Based Molecular Imaging in Designing a Personalized Management Model in Neuroendocrine Tumors; Personalized Clinical Decision Making in GI Malignancies: Where Can PET Help?; PET in Breast Carcinoma: Can it Aid in Developing a Personalized Treatment Design; PET and Thyroid Cancer: Can it Help in Evolving a Personalized Treatment Design?; PET Imaging Towards Individualized Management of Urological and Gynaecological Malignancies; The Possible Role of PET Imaging towards Individualized Management of Bone and Soft Tissue Malignancies; PET-Based Personalized Management of Inflammatory Disorders; PET-Based Radiation Oncology; PET-Based Interventional Radiology; The Current and Evolving Role of PET in Personalized Management of Lung Carcinoma, and more!

This issue of Radiologic Clinics of North America focuses on Extranodal Lymphoma from Head to Toe, and is edited by Dr. Mark Murphey. Articles will include: Pathology of Extranodal Lymphoma; Pulmonary and Mediastinal Extranodal Lymphoma; Gastrointestinal Extranodal Lymphoma; Extranodal Lymphoma Involving the CNS and Spine; Genitourinary Extranodal Lymphoma; Musculoskeletal Extranodal Lymphoma; Pediatric Extranodal Lymphoma; Extranodal Lymphoma of the Breast; Cardiac Extranodal Lymphoma, and more!