This issue covers a wide range of topics related to genitourinary imaging, across a variety of imaging modalities.? An update is given on dual-energy CT in urologic imaging.? Imaging of the retroperitoneum is also discussed. Imaging of infectious and inflammatory diseases of kidneys is reviewed, as is imaging of the features of common and uncommon neoplasms of the bladder.? Multimodality imaging of the ureter, unusual renal masses, and adrenal imaging are all addressed in detail.? Finally, advances in pediatric urologic imaging are reviewed.

As with most joints in the body, MR imaging is highly effective at imaging the shoulder.? This issue reviews the use of MR imaging to rotator cuff disease and external impingement, Internal impingement syndromes, SLAP injuries and microinstability, and glenohumeral instability.? Also included in this issue are separate articles on technical update on MRI of the shoulder, novel anatomic concepts in MR imaging of the rotator cuff, and anatomic variants and pitfalls of the labrum, glenoid cartilage, and glenohumeral ligaments.? The issue also provides reviews of MR Imaging of the postoperative shoulder, MR imaging of the pediatric shoulder, and the throwing shoulder from the orthopedist's perspective.

Since the publication of the best-selling, highly acclaimed first edition, the technology and clinical applications of medical imaging have changed significantly. Gathering these developments into one volume, Webb s Physics of Medical Imaging, Second Edition presents a thorough update of the basic physics, modern technology and many examples of clinical application across all the modalities of medical imaging.

New to the Second Edition

• Extensive updates to all original chapters
• Coverage of state-of-the-art detector technology and computer processing used in medical imaging
• 11 new contributors in addition to the original team of authors
• Two new chapters on medical image processing and multimodality imaging
• More than 50 percent new examples and over 80 percent new figures
• Glossary of abbreviations, color insert and contents lists at the beginning of each chapter

Keeping the material accessible to graduate students, this well-illustrated book reviews the basic physics underpinning imaging in medicine. It covers the major techniques of x-radiology, computerised tomography, nuclear medicine, ultrasound and magnetic resonance imaging, in addition to infrared, electrical impedance and optical imaging. The text also describes the mathematics of medical imaging, image processing, image perception, computational requirements and multimodality imaging. "

PET/CT holds great promise for the management of many types of infection and inflammation.? This issue discusses many of these uses, starting with arthroplasty-associated infection.? FDG PET/CT also has utility in inflammatory bowel disease.? This issue also discusses the utilization of FDG PET and PET/CT in the evaluation of diabetic foot, and in monitoring therapeutic effect in patients without malignancy. PET/CT is reviewed regarding its use in patients with sarcoidosis or IgG4 disease.? Also covered is the application of FDG PET/CT in detecting the source of fever of unknown origin. Artherosclerosis and vasculitis can be assessed by PET/CT and FDG PET/CT can also be used in the management of severe infection in patients with malignancies.? Finally, the issue discusses the use of PET and PET/CT in the evaluation of osteomyelitis.

This issue of Ultrasound Clinics? explores the role that ultrasound plays in diagnosing and treating common disorders of the head and neck. Future applications of ultrasound technology are also discussed. Articles in this issue include "Head and Neck Ultrasound: Why Now?; Ultrasound physics in a nutshell; Head and Neck Anatomy and Ultrasound Correlation; Interpretation of Ultrasound; The Expanding Ultility of Office-Based Ultrasound for the Head and Neck Surgeon;The Role of Ultrasound in Thyroid Disorders; Techniques for Parathyroid Localization and Ultrasound;Ultrasound-Guided Procedures for the Office; Head and Neck Ultrasound in the Pediatric Population; and Emerging Technology in Head and Neck Ultrasonography.

This book collates past and current research on one of the most promising emerging modalities for breast cancer detection. Readers will discover how, as a standalone technology or in conjunction with another modality, microwave imaging has the potential to provide reliable, safe and comfortable breast exams at low cost. Current breast imaging modalities include X- ray, Ultrasound, Magnetic Resonance Imaging, and Positron Emission Tomography. Each of these methods suffers from limitations, including poor sensitivity or specificity, high cost, patient discomfort, and exposure to potentially harmful ionising radiation. Microwave breast imaging is based on a contrast in the dielectric properties of breast tissue that exists at microwave frequencies. The book begins by considering the anatomy and dielectric properties of the breast, contrasting historical and recent studies. Next, radar-based breast imaging algorithms are discussed, encompassing both early-stage artefact removal, and data independent and adaptive beamforming algorithms. In a similar fashion, microwave tomographic reconstruction algorithms are reviewed in the following chapter, introducing the reader to both the fundamental and more advanced algorithms. Apart from imaging, the book also reviews research efforts in extracting clinically useful information from the Radar Target Signature of breast tumours, which is used to classify tumours as either benign or malignant. Finally, the book concludes by describing the current state of the art in terms of prototype microwave breast imaging systems, with a particular emphasis on those which have progressed to the clinical evaluation stage. This work is motivated by the fact that breast cancer is one of the leading causes of death amongst women in Europe and the US, and the second most common cancer in the world today. Such an important area of research will appeal to many scholars and practitioners.p>

Various aspects, including diagnosis, therapy, and prognosis, of two brain tumors (meningioma and schwannoma) , of brain tumors are discussed in this volume. Insights on the understanding of molecular pathways involved in brain tumor biology are explained. For example, the role of E-cadherin gene instability, carbonic anhydrase 11, urokinase plasminogen activator, and Wnt signaling is discussed in detail. Such information will lead to the development of effective aniicancer drugs. The role of molecular genetics and epigenetic mechanisms in schwannomas is explained. Also, is explained the role of cyclin D1 in vestibular schwannoma. The determination of subtypes of meningiomas using perfusion magnetic resonance imaging is explained. Diagnosis of incidentally discovered meningioma and cystic papillary meningioma is also included. Diagnosis of facial nerve schwannoma, vestibular schwannoma, and intermediate nerve schwannoma is explained. Treatments for atypical meningioma, oncocytic meneingioma, intracranial meningioma, and cavernous are presented. Therapeutic methods such as neurosurgery, Gamma knife radiosurgery, and adjuvant radiation for this cancer are included. Large number of other treatments, including radiosurgery, retrosigmoidal craniotomy, and immunotherapy, for vestibular schwannoma patients are detailed.

Gain a complete understanding of sonography physics and instrumentation related to clinical practice. Technology for Diagnostic Sonography provides clear, in-depth coverage of physics principles, ultrasound transducers, pulse echo instrumentation, Doppler instrumentation, clinical safety, and quality control. It includes the latest information on real-time imaging techniques, plus a comprehensive discussion of image artifacts. With wide-ranging online review questions, it also offers ample opportunities to assess your learning progress. Written by sonography and testing expert Wayne Hedrick, Technology for Diagnostic Sonography simplifies this difficult topic and allows you to demonstrate your knowledge of physics and instrumentation on exams with the ultimate goal of preparing you for success in clinical practice. A focus on essential physics and instrumentation provides the exact technical content you need to prepare for clinical sonography practice. Accessible, conversational writing style with real-world analogies explains physics concepts and makes this difficult topic less intimidating. Examples and sample problems help you make the connection between theory and practical applications. The latest information on equipment and scanning methods ensures an understanding of how to competently and safely use ultrasound instrumentation. Comprehensive discussion of image artifacts with illustrative examples helps you recognize and eliminate artifacts. Detailed description of performance testing with tissue mimicking phantoms allows assessment of the proper operation of B-mode scanners. Practical guidance on the clinical use of mechanical index and thermal index enables practice of the ALARA principle when scanning patients. Full-color format shows scans as they appear in the clinical setting. Key terms and other learner-friendly features focus your study on important information. Summaries of essential principles and equations reinforce the most important concepts. Extensive review questions on a companion Evolve website allow realistic assessment of your knowledge.

This issue provides a complete update on PET imaging of lymphoma, starting with a clinical assessment of lymphoma and the role of medical imaging. The role of structural imaging in lymphoma is then discussed.? From a Nuclear Medicine perspective, FDG-PET in lymphoma is reviewed, as is the role of FDG-PET in pediatric lymphoma.? Next, the role of non-FDG tracers in lymphoma is reviewed.? Other articles cover the role of fMRI and optical imaging in lymphoma, the role of diffusion-weighted MRI in lymphoma, FDG-PET in personalization of therapy in patients with lymphoma, and PET and radiation oncology in lymphoma.

This volume of Methods in Enzymology is thethird of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike.
The third of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cellsThe chapters provide hints and tricks not available in primary research publicationsIt is an invaluable resource for academics, researchers and students alike"

Cutting edge information for all oral and maxillofacial surgeons on computed tomography and guided surgery! Topics include comparison of CT and cone beam technologies, stereolithographic modeling and surgical guide concepts, virtual technologies in dentoalveolar evaluation and surgery, computer guided planning and placement of dental implants, utilization in the treatment of facial trauma, digital technologies in pathology and reconstruction, 3D technologies in craniofacial and orthognathic surgery, evaluation and fabrication of custom cosmetic facial implants, and extraoral craniofacial applications.

Electromyography remains a main diagnostic tool within neurology. This issue of Neurologic Clinics addresses the most recent developments in the clinical application of EMG. Articles in this issue include: Nerve conduction studies: Basic Concepts and Patterns of Abnormalities; Needle Electromyography-Basic Concepts andInterpretation of Recorded Potentials;Electrodiagnostic Evaluation of Carpal TunnelSyndrome;Electrodiagnostic Evaluation of Ulnar Neuropathyand Other Upper Extremity Mononeuropathy; Lower Extremity Mononeuropathies;Electrodiagnostic Evaluation of Brachial Plexopathies; Evaluation ofRadiculopathies;Electrodiagnostic Approach to Motor NeuronDiseases;Electrophysiologic Findings in PeripheralNeuropathies; Evaluation of Neuromuscular Junction Disorders in the EMGLaboratory;Electrodiagnostic Findings inMyopathy;Electrodiagnostic Approach to CranialNeuropathies; Technical Issues with Nerve Conduction Studies and Needle EMG;andCoding and Reimbursement of ElectrodiagnosticStudies.

This volume of Methods in Enzymology is the first of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike.
Expert authors who are leaders in the fieldExtensively referenced and useful figures and tablesProvides hints and tricks to facilitate reproduction of methods

Topics include: MRI of the preterm and term neonate with hypoxic ischemic injury; MRI of neonatal infections; MRI of neonatal stroke; Neonates with seizures: What to consider, How to image?;? Metabolic diseases of the newborn; Fetal MRI: Imaging versus imagining?; Postmortum MRI: An alternative to autopsy?; MRI of spinal dysraphia: What to consider?; Diffusion Tensor Imaging of the neonatal spinal cord; How to prepare and care for a critical sick neonate in a MRI environment; Functional (BOLD) imaging of the newborn; Advanced functional MRI; Dedicated MR antennae for neonatal imaging; Shaken infant syndrome/ Imaging of child abuse; Congenital Cardiac Defects and MR guided planning of surgery; Congenital Cardiovascular Malformation: Non-invasive imaging; MR guided cardiovascular interventions in noenates and infants; Musculoskeletal imaging of the newborn.

Since the early 20th century, medical imaging has been dominated by monochrome imaging modalities such as x-ray, computed tomography, ultrasound, and magnetic resonance imaging. As a result, color information has been overlooked in medical image analysis applications. Recently, various medical imaging modalities that involve color information have been introduced. These include cervicography, dermoscopy, fundus photography, gastrointestinal endoscopy, microscopy, and wound photography. However, in comparison to monochrome images, the analysis of color images is a relatively unexplored area. The multivariate nature of color image data presents new challenges for researchers and practitioners as the numerous methods developed for monochrome images are often not directly applicable to multichannel images. The goal of this volume is to summarize the state-of-the-art in the utilization of color information in medical image analysis.

A global pool of surgeons and researchers using 3-dimensional imaging for facial plastic surgery present topics on: Image fusion in pre-operative planning; The use of 3D imaging tools including stereolithographic modeling and intraoperative navigation for maxillo-mandibular and complex orbital reconstruction; Custom-made, three-dimensional, intraoperative surgical guides for nasal reconstruction; The benefits and limits of using an integrated 3D virtual approach for maxillofacial surgery; 3D volume assessment techniques and computer-aided design and manufacturing for pre-operative fabrication of implants in head and neck reconstruction; A comparison of different new 3D imaging technologies in facial plastic surgery; 3-D photography in the objective analysis of volume augmentation including fat augmentation and dermal fillers; Assessment of different rhinoplasty techniques by overlay of before and after 3D images; 3D volumetric analysis of combined facial lifting and volumizing (volume enhancement); 3-D facial measurements and perceptions of attractiveness; Teaching 3-D sculpting to Facial Plastic Surgeons, 3-D insights on aesthetics; Creation of the virtual patient for the study of facial morphology; 3-dimensional video analysis of facial movement; 3D modeling of the behavior of facial soft tissues for understanding facial plastic surgery interventions

This issue of Radiologic Clinics updates the reader with the latest clinical information on the imaging of bone and soft-tissue tumors.? An article on how to approach patients with bone lesions leads off the issue followed by reviews of analysis of solitary lesions of bone, imaging of benign bone tumors, imaging of primary malignant bone tumors, and imaging of hematopoietic tumors and metastases involving bone.? Soft tissue tumors are also reviewed in articles from the clinician's perspective and with the use of MRI.? The use of MRI in the imaging of children with soft tissue masses is also covered.? Articles on mimics of bone and soft tissue tumors, biopsy and intervention, post-therapy imaging, and advanced MRI techniques round out the issue.

Ultrasound is used frequently as the modality of choice for vascular imaging.? It's unique ability to demonstrate blood flow make it particularly effective.? Reviewed in this issue are the US applications in the imaging of the heart, kidneys, and liver.? Also covered are imaging of US for imaging of the carotid artery and in deep vein thrombosis.? Lastly an article highlighting ways to optimize Doppler US is included.

Diseases once believed to be confined to the tropics, such as parasitic, mycobacterial, fungal, bacterial, and viral infections are still a major cause of mortality and moribidity in the tropics, yet can affect the developed world in an era of increased global travel and migration. Neuroimaging technique developments over the last several decades have helped clinicians better understand and diagnose these conditions. Experts from tropical countries share their experiences regarding tropical disorders, some of which are rare in the western world, but possible to appear in patients and not readily recognized by specialists not familiar with these diseases.

Topics in this issue include: Relevance of neuroimaging in the diagnosis and management of tropical neurologic disorders; Pathology of Tropical Diseases; Viral Infections of the Central Nervous System; Central Nervous System Tuberculosis; Parasitic diseases of nervous system; Neuroimaging in Post-infectious Demyelination and Nutritional Disorders of the Central Nervous System; CNS Fungal Infections in the Tropics; Neuroimaging Epilepsy in the Tropics; Neuroimaging in Cranio-Vertebral Anomalies as seen in Tropics; Vascular Brain Pathologies; Neurobrucellosis; Hirayama Disease; Transverse Myelitis; and Pyomyositis.

Congenital spine and spinal cord malformations; Congenital brain malformations (except cortical malformations); Malformations of cortical development; Congenital cystic neck lesions; A simplified approach to pediatric vascular malformations of the head and neck; Congenital face, maxillofacial anomalies; Congenital arterial and venous anomalies of brain, spine and neck; Fetal neuroimaging; Temporal bone malformations; Pediatric orbit; Neurosurgeon's perspective to congenital brain and spine malformations

This issue provides an overview of anatomy for the practicing radiologist using MR.? Neuroanatomy is covered in separate articles on the brain, neck, spine, and skull base.? Body imaging is reviewed in articles on chest, abdomen, breast, and pelvis, and finally, the musculoskeletal system is thoroughly displayed by articles on shoulder, elbow, wrist and hand, knee, and ankle and foot.? Long bones of the upper and lower extremities are reviewed in separate articles as well.

Because of the number and variety of illnesses that can affect the pediatric respiratory system, being able to interpret thoracic images of children is important for the general radiologist.? This issue of Radiologic Clinics starts off with an overview of lung and pleural infections.? Reviews of small and large airway diseases are followed by separate articles on the uses of ultrasound, MR, and nuclear medicine to image pediatric patients.? Also included are articles on lung and vascular anomalies, thoracic trauma, and cardiac disease.? The issue is completed with articles on fetal lung imaging and radiation safety.

This book examines non-invasive, electrical-based methods for disease diagnosis and assessment of heart function. In particular, a formalized signal model is proposed since this offers several advantages over methods that rely on measured data alone. By using a formalized representation, the parameters of the signal model can be easily manipulated and/or modified, thus providing mechanisms that allow researchers to reproduce and control such signals. In addition, having such a formalized signal model makes it possible to develop computer tools that can be used for manipulating and understanding how signal changes result from various heart conditions, as well as for generating input signals for experimenting with and evaluating the performance of e.g. signal extraction methods. The work focuses on bioelectrical information, particularly electrical bio-impedance (EBI). Once the EBI has been measured, the corresponding signals have to be modelled for analysis. This requires a structured approach in order to move from real measured data to the model of the corresponding signals. This book proposes a generic framework for this procedure. It can be used as a guide for modelling impedance cardiography (ICG) and impedance respirography (IRG) signals, as well as for developing the corresponding bio-impedance signal simulator (BISS).

Breast sonography is commonly used to evaluate mammographic and palpable abnormalities, and this issue covers all of the current applications currently in use. Sonography also plays a role in screening for breast cancer and in evaluating the extent of disease in the breast and the regional lymph nodes. This issue also reviews the use of ultrasound to perform biopsies, guide catheters, and deliver radiation therapy.

Since scientists began experimenting with green fluorescent proteins in the middle of the 1990s, these proteins have become one of the most important tools available to researchers in modern medicine and biology. By using them to illuminate other proteins that were previously invisible even under microscope, scientists are now able to observe facets of disease that would have otherwise gone undetected. Green fluorescent proteins are a part of over three million experiments a year, and are invaluable for tasks such as tracking HIV, breeding bird flu-resistant chickens, and confirming the existence of cancerous stem cells. In Illuminating Disease, Marc Zimmer introduces us to these revolutionary proteins, acquainting readers both with the researchers responsible for the proteins' discovery as well as their wide utility. The book details the history of genetically modified fluorescent parasites and viruses, which provide scientists with new information about the spread of diseases. Green fluorescent proteins have played crucial roles in the research of malaria, AIDS/HIV, swine and bird flu, dengue, cancer, and chagas. They allow scientists and doctors to understand these diseases better, by quite literally illuminating various microscopic pieces that otherwise would have gone unseen. The book is richly illustrated, showing the many visually striking uses of GFP. Many of these scans have won awards in biological imaging competitions. Illuminating Disease is an accessible and illustrated introduction to one of the most important developments in medical research of the last several decades.