Volume 22, entitled Metal Ions in Bio-Imaging Techniques, of the series Metal Ions in Life Sciences deals with metal ions as tools in imaging. This dates back to the first half of the past century, when barium sulfate was orally given to patients undergoing X-ray examination. The use of contrast agents has since developed into a large interdisciplinary field encompassing not only medicine, but also chemistry, material sciences, physics, biology, engineering, and computer sciences. MILS-22 provides deep and current insights in 17 stimulating chapters on the new research frontiers of this fast growing field on bio-imaging ... and beyond. For example, adding bio-sensing yields theranostic agents, meaning diagnosis and therapy linked in the same molecule; ions of Gd, Mn, Fe, Co, Ir, 99mTc, etc., are involved. Other important topics are, e.g., metal complexes in paramagnetic Chemical Exchange Transfer (paraCEST), radiometals for Positron Emission Tomography (PET) imaging, or paramagnetic metal ion probes for 19F magnetic resonance imaging. MILS-22 is written by 57 internationally recognized experts from 12 countries, that is, from the US via Europe to China. The impact of this vibrant research area is manifested by more than 2300 references and nearly 120 figures, mostly in color, and several informative tables. To conclude, Metal Ions in Bio-Imaging Techniques is an essential resource for scientists working in the wide range from material sciences, enzymology, analytic, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that also excellent information for teaching is provided.

This issue of MRI Clinics of North America focuses on Breast Cancer, and is edited by Dr. Jessica Leung. Articles will include: Breast MRI: Atlas of anatomy, physiology, pathophysiology, and BI-RADS lexicon; Neoadjuvant therapy monitoring, including inflammatory breast cancer; Breast MRI biopsy considerations: Technique, histologic upgrading, and radiologic-pathologic concordance; Breast MRI techniques and developments: 1.5 vs 3T, diffusion, fast MRI, PET-MRI, and other developing techniques; ACR Accreditation, Performance Metrics, Reimbursement, and Economic Considerations in Breast MRI; Screening: high-risk and dense breasts, especially compared with tomosynthesis and ultrasound; Extent of breast disease, especially compared with tomosynthesis and ultrasound, with special focus on nodal assessment; Problem-solving tool for imaging finding and clinical symptoms of breast cancer; MRI compared with contrast-enhanced mammography; MRI compared with molecular breast imaging; MRI compared with positron emission mammography; How does MRI help care for my breast cancer patient? Perspective of a surgical oncologist; How does MRI help care for my breast cancer patient? Perspective of a medical oncologist; How does MRI help care for my breast cancer patient? Perspective of a radiation oncologist; and more!

Provides concise, handy and clear reference and in-depth knowledge of various ultrasound images in relation to various disease entities of different systems of the body so as to arrive at a correct diagnosis. Serves as an essential guide to practicing radiologists, sonologists, obstetricians and gynaecologists, physicians and surgeons and also to postgraduate students in their examination.

Dr. Leonard Swischuk, who is recognized for authoring several superb and widely read pediatric radiology textbooks, has produced yet another outstanding work on the important subject of imaging the cervical spine in children. A distinguished pediatric radiologist, he draws upon his extensive experience in the field and his gift for writing clear and readable text to provide practitioners with an insightful approach to pediatric cervical spine injuries. Those who work in trauma imaging will appreciate the wealth of practical guidelines contained in this thorough yet concise book. Dr. Swischuk's text is organized into six chapters. The first two discuss developmental anatomy and normal variants. Chapters three and four concentrate on congenital anomalies and on abnormalities of the dens. The final two chapters consider trauma and miscellaneous abnormalities of the cervical spine. The book has several notable strengths that are appealing to radiology residents, such as its succinct and well-organized overview of the topic. To help residents identify cases that they are likely to encounter during board exams and in practice, Dr. Swischuk selected excellent plain film examples from his personal collection that illustrate the conditions he discusses and reflect his emphasis on cervical radiography. The illustrated cases also include CT and MR images that clarify and qualify the plain film findings. Helpful reference lists complete each chapter and guide residents to resources for further reading. In addition, Dr. Swischuk 's direct writing style makes the complex content highly accessible, providing imaging residents with an invaluable introduction to pediatric cervical spine radiology.

This book systematically introduces readers to the fundamental physics and a broad range of applications of acoustic levitation, one of the most promising techniques for the container-free handling of small solid particles and liquid droplets. As it does away with the need for solid walls and can easily be incorporated into analysis instruments, acoustic levitation has attracted considerable research interest in many fields, from fluid physics to material science. The book offers a comprehensive overview of acoustic levitation, including the history of acoustic radiation force; the design and development of acoustic levitators; the technology's applications, ranging from drop dynamics studies to bio/chemical analysis; and the insightful perspectives that the technique provides. It also discusses the latest advances in the field, from experiments to numerical simulations. As such, the book provides readers with a clearer understanding of acoustic levitation, while also stimulating new research areas for scientists and engineers in physics, chemistry, biology, medicine and other related fields.

A prize-winning medical writer offers an explanation of modern diagnostic medical imaging technologies-and the issues that result from their use and misuse. Medical Imaging describes the discovery and development of diagnostic imaging technologies, explaining how the technologies work and exploring some of the issues that such powerful and expensive technologies create. The book begins with the discovery of X-rays in 1895 and traces the history of imaging technology through today's tools, such as X-ray computed tomography, magnetic resonance imaging (MRI), functional imaging by positron emission tomography (PET), and single photon emission computed tomography (SPECT). The contribution of these expensive technologies to the rising cost of healthcare in the United States and the unequal distribution of imaging diagnostic facilities, particularly in developing countries, is also considered. In addition, the book explores ethical questions that have surfaced in the past, including the reportability of incidental findings during a scan and admissibility of medical images as evidence in courts of law , and such newly emerging issues as the application of imaging tools in lie detection and the mammography guidelines controversy of 2009. Various charts and illustrations show medical imaging modalities, Medicare medical imaging costs, distribution of imaging costs, physicians' fees by modality, nuclear imaging probes, and medical imaging physics A glossary defines key terms necessary to understanding medical imaging technology such as "positron," "half-life," and "tomography," as well as acronyms such as "MRI,", "PET," "SPECT," and "CT" Presents documents including early popular science articles on X-ray technology and its abuse

The second of two companion books which address the biology and clinical aspects of prostate cancer. This volume, Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, discusses both classic and the most recent imaging approaches for detection, early diagnosis and treatment of prostate cancer. The companion title, Cell & Molecular Biology of Prostate Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature.

Soft Computing Based Medical Image Analysis presents the foremost techniques of soft computing in medical image analysis and processing. It includes image enhancement, segmentation, classification-based soft computing, and their application in diagnostic imaging, as well as an extensive background for the development of intelligent systems based on soft computing used in medical image analysis and processing. The book introduces the theory and concepts of digital image analysis and processing based on soft computing with real-world medical imaging applications. Comparative studies for soft computing based medical imaging techniques and traditional approaches in medicine are addressed, providing flexible and sophisticated application-oriented solutions.

This issue of PET Clinics focuses on Lung Cancer, and is edited by Drs. Gang Cheng and Timothy Akhurst. Articles will include: FDG PET/CT for lung cancer staging; Lung neoplasms with low FDG avidity; FDG PET/CT evaluation of lung cancer in populations with high prevalence of granulomatous disease; Prognostic value of FDG PET/CT; Genomic characterization of lung cancer and its impact on the use and timing of PET in therapeutic response assessment; Treatment planning for radiation therapy; Future directions of PET imaging for lung cancer; PET for RT-planning in lung cancer; Genomic characterization of lung cancer and its impact on the use and timing of PET in therapeutic response assessment; and more!

Spin Resonance Spectroscopy: Principles and Applications presents the principles, recent advancements and applications of nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) in a single multi-disciplinary reference. Spin resonance spectroscopic techniques through NMR and EPR are widely used by chemists, physicists, biologists and medicinal chemists. This book addresses the need for new spin resonance spectroscopy content while also presenting the principles, recent advancements and applications of NMR and EPR simultaneously. Ideal for researchers and students alike, the book provides a single source of NMR and EPR applications using a dynamic, holistic and multi-disciplinary approach.

Completely up to date with the latest examination changes, Get Through First FRCR: MCQs for the Physics Module offers a valuable insight into the new Physics module of the First FRCR examination. Over 200 5-part True/False MCQs are presented according to syllabus topics, accurately reflecting the content, style and level of difficulty of the actual examination questions. All answers are supplemented with clear, detailed explanations to develop candidates' understanding and to explain why their answers are right, or wrong. Featuring a wealth of practice MCQs plus one full mock examination, this book has been designed for candidates to assess their knowledge, identify topics that require further study and to build up confidence in preparation for the exam day. Written by Specialty Trainees in Radiology, under the guidance and expertise of Jerry Williams, Consultant Medical Physicist, Get Through First FRCR: MCQs for the Physics Module is the essential revision tool for all First FRCR candidates preparing for the newly revised examination.

Use today's latest technology and methods to optimize imaging of complex skull base anatomy. This practical reference offers expert guidance on accurate preoperative lesion localization and the evaluation of its relationship with adjacent neurovascular structures. Features a wealth of information for radiologists and surgeons on current CT and MR imaging as they relate to skull base anatomy. Covers localizing skull base lesions, reaching the appropriate differential diagnosis, and deciding which surgical approach is best. Consolidates today's available information and guidance in this challenging area into one convenient resource.

This issue of Neuroimaging Clinics of North America focuses on Imaging of Brain Concussion, and is edited by Drs. Roy Riascos and Eliana E. Bonfante-Mejia. Articles will include: Traumatic Brain Injury: definition, neurosurgery, trauma-orthopedics, neuroimaging, and psychology-psychiatry; Multimodality advanced imaging for brain concussions; Perfusion weighted images in brain concussion; PET and SPECT in brain concussion; Imaging of chronic concussion; Imaging of concussion in young athletes; Imaging on concussion in blast injury; Conventional CT and MR in brain concussion; Structural imaging: structural MRI in concussion; Susceptibility weighted imaging and MR spectroscopy in concussion; Functional imaging fMRI - BOLD and resting state techniques in mTBI; Diffusion Weighted and Diffusion Tensor Imaging in mTBI; and more!

This issue of Neuroimaging Clinics of North America focuses on Dual Energy CT: Applications in Neurologic, Head and Neck Imaging, and is edited by Drs. Reza Forghani and Hillary R. Kelly. Articles will include: Dual Energy CT: Physical Principles and Approaches to Scanning, Part 1; Dual Energy CT: Physical Principles and Approaches to Scanning, Part 2; Dual Energy CT Applications for Differentiation of Intracranial Hemorrhage, Calcium, and Iodine; Dual Energy CT Angiography of the Head and Neck and Related Applications; Miscellaneous and Emerging Applications of Dual Energy CT for the Evaluation of Intracranial Pathology; Applications of Dual Energy CT for the Evaluation of Head and Neck Squamous Cell Carcinoma; Dual Energy CT Applications for the Evaluation of Cervical Lymphadenopathy; Miscellaneous and Emerging Applications of Dual Energy CT for the Evaluation of Pathologies in the Head and Neck; Dual Energy CT Applications for the Evaluation of the Spine; Applications of Dual Energy CT for Artifact Reduction in the Head, Neck, and Spine; Advanced Tissue Characterization and Texture Analysis using Dual Energy CT: Horizons and Emerging Applications; and more!

This issue of MRI Clinics of North America focuses on Update on Imaging Contrast Agents, and is edited by Drs. Carlos Zamora, Mauricio Castillo, Richard Semelka. Articles will include: Historical Perspective of Imaging Contrast Agents; Current Radiographic Iodinated Contrast Agents; Contrast-enhanced Sonography; Myelography: From Lipid-based to Gadolinium-based Contrast Agents; Acute Allergic Reactions with Gadolinium-based Contrast Agents: Diagnosis and Treatment; Deposition and Chronic Toxicity of Gadolinium-based Contrast Agents; Managing Allergic Reactions to Contrast Agents; Safety of Contrast Material Use in Children; Molecular Imaging and Contrast Agents; Contrast Agents for MR Imaging: Gadolinium, Manganese, SPIO, Superparamagnetic Iron Platinum, and Oral Agents; Contrast-induced Nephropathy: Pathophysiology, Manifestations, Prevention, and Management; and more!

This issue of Neuroimaging Clinics of North America focuses on Functional Connectivity, and is edited by Dr. Jay Pillai. Articles will include: Applications of rs-fMRI to presurgical mapping: sensorimotor mapping; Dynamic functional connectivity methods; Machine learning applications to rs-fMRI analysis; Frequency domain analysis of rs-fMRI; Applications of rs-fMRI to epilepsy; Data-driven analysis methods for rs-fMRI; Applications of rs-fMRI to presurgical mapping: language mapping; Limitations of rs-fMRI in the setting of focal brain lesions; Applications of rs-fMRI to neuropsychiatric disease; Applications of rs-fMRI to Traumatic Brain Injury; Applications of rs-fMRI to neurodegenerative disease; Graph theoretic analysis of rs-fMRI; and more!

This issue of Radiologic Clinics of North America focuses on Imaging and Cancer Screening, and is edited by Dr. Dushyant Sahani. Articles will include: Imaging and Screening of Thyroid Cancer; Imaging and Screening of Lung Cancer; Imaging and Screening of Breast Cancer; Imaging and Screening of Liver Cancer; Imaging and Screening of Cancer of the Gall Bladder and Bile Ducts; Imaging and Screening of Pancreatic Cancer; Imaging and Screening of Kidney Cancer; Imaging and Screening of Cancer of the Small Bowel; Imaging and Screening of Colon Cancer; Imaging and Screening of Ovarian Cancer; Imaging and Screening of Genetic Syndromes; and more!

Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Head and Neck, fourth edition, is an invaluable resource for neuroradiologists, general radiologists, and trainees-anyone who requires an easily accessible, highly visual reference on today's head and neck imaging. Dr. Philip R. Chapman and his team of highly regarded experts provide up-to-date information on recent advances in disease identification, imaging techniques, and tumor staging to help you make informed decisions at the point of care. The text is lavishly illustrated, delineated, and referenced, making it a useful learning tool as well as a handy reference for daily practice. Serves as a one-stop resource for key concepts and information on head and neck imaging, including a wealth of new material and content updates throughout Features more than 2,800 illustrations including radiologic images, full-color illustrations, clinical and gross pathology photographs, and histology photographs, as well as an additional 2,200 digital images online Features numerous new chapters and updates from cover to cover including changes to staging of HPV-related/p16(+) oropharyngeal squamous cell carcinoma; new metastatic disease imaging recommendations, protocols, and treatments; and the latest knowledge on the genetics of various congenital conditions and syndromes Reflects new Lugano and WHO classifications for staging lymphomas; updates in the AJCC Cancer Staging Manual, 8th Edition; and updates from the 2018 ISSVA Classification regarding avoidance of outdated and inappropriate terminology and nomenclature that can lead to misdiagnosis or inappropriate treatments Uses bulleted, succinct text and highly templated chapters for quick comprehension of essential information at the point of care Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Dr. Gress has assembled top experts to discuss the latest advances of using endoscopic ultrasound for diagnostic and therapeutic purposes. The issue has review articles devoted to the following topics: EUS Elastography; Contrast-Enhanced EUS; New developments in EUS- FNA Tissue Acquisition; EUS FNA: Cytologic and histologic using new techniques for interpretation; New EUS Techniques for diagnosing pancreatic neoplasms; EUS for diagnosing and treating pancreatic cysts; The role of EUS in the diagnosis of Autoimmune Pancreatitis; Therapeutic EUS for cancer treatment; and EUS-guided techniques in biliary drainage, pancreatic drainage, necrosectomy, pelvic fluid collections, hemostasis techniques, and gastrojejunostomy. The issue ends with articles that look at training issues and the future of EUS. Readers should leave with the clinical information they need to embrace the latest advances of endoscopic ultrasonography.

Meticulously updated by board-certified oral and maxillofacial radiologist, Dr. Dania Tamimi and her team of sub-specialty experts, Specialty Imaging: Temporomandibular Joint and Sleep-Disordered Breathing, second edition, is a comprehensive reference ideal for anyone involved with TMJ imaging or SDB, including oral and maxillofacial radiologists and surgeons, TMJ/craniofacial pain specialists, sleep medicine specialists, head and neck radiologists, and otolaryngologists. This detailed, beautifully illustrated volume covers recent advances in the diagnosis and treatment of both the TMJ and SDB, including how related structures are affected. Employing a multifaceted, multispecialty approach, the clinical perspectives and imaging expertise of today's research specialists are brought together in a single, image-rich, easy-to-read text. Reflects the current emphasis on holistic diagnosis and treatment not just of the TMJ but of all related structures that can be adversely affected by any TMJ dysfunction  Examines a variety of presenting clinical signs or symptoms, discusses imaging strategies and  the associated conditions revealed by imaging, and helps you develop differential diagnoses  Provides current, detailed information on the relationship between TMJ disorders and SDB, how imaging shows the correlation between the two, and risk factors for SDB  Includes upper respiratory tract diagnoses, with multiple subsections on the nasal cavity, paranasal sinuses, nasopharynx, oropharynx, and hypopharynx, each with multiple new chapters  Features new chapters on ultrasonography of the TMJ and upper respiratory tract, new content on 3D and 4D modeling and surface rendering, a new section on imaging of upper respiratory tract procedures, and new content detailing the tie-in between occlusion and SDB  Includes an expanded Modalities section that includes new chapters on formulating a TMJ/upper respiratory tract report; plain film imaging of the TMJ and upper respiratory tract; CBCT analysis of the upper respiratory tract; dynamic MR of the TMJ and upper respiratory tract, and ultrasound of the TMJ   Covers the role that TMJ plays in facial growth and development, stomatognathic system function, and how TMJ abnormalities change the dimensions of the facial skeleton and surrounding structures  Contains over 5,000 print and online-only images (more than 300 are new), including radiologic images, full-color medical illustrations, and histologic and gross pathology photographs  Reflects updates to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC-TMD)-the major clinical classification method and a key tool to assess/diagnose TMJ issues and facilitate communication for consultants, referrals, and prognoses  Includes an eBook version?that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud 

This issue of MRI Clinics of North America focuses on Imaging of the Female Pelvis, and is edited by Katherine Maturen. Articles will include: MR Imaging of Adnexal Mass Characterization; MR Imaging of Abnormal Placentation; MR Imaging of the Pelvic Floor; MR-Pathologic Correlation of Ovarian Neoplasms; MR Imaging of Benign Uterine Pathologies; MR Imaging for Gynecologic Brachytherapy; MR Imaging of Mullerian Fusion Anomalies; MR Imaging in Cervical Cancer; MR Imaging in Female Pelvic Emergencies; MR Imaging in Endometrial Cancer; MR Imaging of the Female Perineum; PET/MR in Gynecologic Oncology; MR Imaging of Vulvar and Vaginal Cancer; and more!

This issue of Radiologic Clinics of North America focuses on Imaging of Rheumatology, and is edited by Dr. Giuseppe Guglielmi. Articles will include: What the Rheumatologist is Looking For and What the Radiologist Should Know; Conventional Radiology in Rheumatoid Arthritis; Conventional Radiology in Spondyloarthritis; Conventional Radiology in Crystal Arthritis: Gout, Calcium Pyrophosphate Deposition, and Basic Calcium Phosphate Crystals; Ultrasound in Arthritis; Computed Tomography and Magnetic Resonance Imaging in Rheumatoid Arthritis; Computed Tomography and Magnetic Resonance Imaging in Spondyloarthritis; Computed Tomography and Magnetic Resonance Imaging in Crystal Arthritis; SAPHO and Recurrent Multifocal Osteomyelitis; Paediatric Vasculitis; Myopathies; Juvenile Arthritis and Other Pediatric Rheumatologic Disorders; Imaging of Post-Traumatic Arthritis, Aseptic Necrosis, Septic Arthritis, Sudek's Osteodystrophy, and Cancer Mimicking Arthritis; Imaging in Osteoarthritis; Interventions and Therapy in Rheumatology, and more!

This issue of PET Clinics focuses on Molecular Imaging and Precision Medicine, Part II, and is edited by Dr. Rathan Subramaniam. Articles will include: Precision Medicine in Esophageal Cancer; Precision Medicine and PET/CT in Melanoma; Precision Medicine and PET/CT in Hepatobilliary and Pancreatic Cancer; Precision Medicine and PET/CT in Gastric Cancer; Precision Medicine and PET/CT in Skeletal and Soft Tissue Sarcomas; Precision Medicine and PET/MRI; Precision Medicine and PET/CT in Uterine and Ovarian Cancers; Precision Medicine and PET/CT in Cardiovascular Disorders, and more!

This issue of Radiologic Clinics of North America focuses on Practical Pediatric Imaging, and is edited by Dr. Edward Lee. Articles will include: Practical Imaging Approach to Traumatic Brain Injuries in Children; Pediatric Thoracic Normal Variants: What Should Radiologists Need to Know?; Respiratory Distress in Neonates: Underlying Etiologies and Imaging Assessment; Child with Cough and Fever: Up to Date Imaging Evaluation and Management; Thoracic Neoplasms in Children: Contemporary Perspectives and Imaging Assessment; Cardiovascular Malformations in Children: Current Indications, Techniques, and Imaging Findings; Neonatal Gastrointestinal Emergencies: Step-by-Step Approach; Pediatric Abdominal Neoplasms: An Overview and Update; Musculoskeletal Traumatic Injuries in Children: Characteristic Imaging Findings; Practical Imaging Evaluation of Foreign Bodies in Children: What Is New?; Syndromic Disorders Associated with Pediatric Tumors: Spectrum of Diseases and Imaging Findings; Practical Indication-Based Pediatric Nuclear Medicine Studies: Update and Review; and more!