This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled "Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. "The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis. Truly, a new era has arrived with clinical use of nuclear medicine and molecular imaging for personalized medicine. This volume will benefit a wide variety of researchers in life science including those working in drug development, molecular imaging, and medical therapy as well as physicians who utilize diagnostic imaging.

Using a clear and concise format, Introduction to Radiologic and Imaging Sciences and Patient Care, 7th Edition delivers the latest radiologic, imaging science and patient care skills you need to prepare for certification and practice. This new edition includes updates on current digital imaging and instrumentation, providing you with the essential information and tools needed to master any introduction to radiologic sciences class. Chapter review questions and lab activities available online and on tear sheets in the text give you easy access to on-the-go learning. This text not only helps to prepare you for parts of the certification exam, but the content provides useful and practical information that is needed for professional practice and clinical success. Step-by-step procedures presented in boxed lists throughout the text supply you with easy to follow steps so you are well prepared for clinical success. Back-of-book review questions provide you with an opportunity for review and greater challenge. More than 300 photos and line drawings help you understand and visualize patient-care procedures. Strong pedagogy, including chapter objectives, key terms, outline and summaries helps you organize information and ensure that you understand what is most important in every chapter. NEW and UPDATED! Updates on current digital imaging and instrumentation provide you with the important information you need for clinical success. NEW! The latest technical terminology incorporated throughout text keeps you up-to-date with industry verbiage. NEW and UPDATED! Appendices containing practice standards, professional organizations, state licensing agencies, the ARRT code of ethics and patient care partnership offer you additional information about professional opportunities and obligations and prepare you for what you will encounter in the practice environment.

The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. A detailed, pattern-based approach to abdominal imaging interpretationDiagnostic Abdominal Imaging provides a comprehensive review of abdominal diseases based onpattern recognition. Utilizing more than 2,300 images, the book includes discussions of the x-ray, sonographic, CT, MRI, and nuclear radiology features of abdominal diseases. Since accurate imaging diagnosis of diseases can only be achieved with the appropriate clinical history, thecharacteristic clinical presentations of abdominal diseases are discussed in conjunction with the image findings. Presented in fifteen organ-based chapters that highlight differentiation of disease on the basis of imaging patterns, Diagnostic Abdominal Imaging discusses the full spectrum of malignant and nonmalignant abdominal disorders. Each discussion begins with the most salient histologic, pathologic, and clinical features of the disorder under discussion. This is followed by a systematic review of the imaging features of the disease as seen by all modalities. Unlike most radiology texts which are organized by pathology, Diagnostic Abdominal Imaging isorganized by imaging appearance-mimicking real-world practice. The book guides you through the process of imaging-based diagnosis and stresses the epidemiological, clinical, and imaging features that allow the most accurate prediction of disease. Features: More than 2,300 images Clear, concise guidelines for determining a diagnosis Imaging Notes emphasize the critical features of imaging interpretation Designed to simulate the routine daily analysis that leads to a diagnosis

The International Commission on Radiological Protection (ICRP) has developed and systematically updated the system of radiological protection, which now recommends optimisation of protection measures within or guided by appropriate restrictions, such as dose constraints or reference levels, in all circumstances. This applies to all exposure situations (planned, emergency and existing) and all categories of exposure (occupational, medical, and public). Optimisation of protection is intended to reduce exposures to levels that are as low as reasonably achievable, economic and societal considerations being taken into account, and to manage medical exposures commensurate with the medical purpose.

Biomathematical Problems in Optimization of Cancer Radiotherapy provides insight into the role of cell population heterogeneity in the optimal control of fractionated irradiation of tumors. The book emphasizes the mathematical modeling aspect of the problem and presents the state of the art in the stochastic description of irradiated cell survival. Some of the results are of general theoretical interest and can be applied to other areas of optimal control methodology. Detailed explanations of all mathematical statements are provided throughout the text. The book is excellent for biomathematicians, radiotherapists, oncologists, health physicists, and other researchers and students interested in the topic.

The goal of external beam radiotherapy is to provide precise dose localisation in the treatment volume of the target with minimal damage to the surrounding normal tissues. Ion beams, such as protons and carbon ions, provide excellent dose distributions due primarily to their finite range, allowing a significant reduction of undesired exposure to normal tissues. Careful treatment planning is required for the given type and localisation of the tumour to be treated in order to maximise the treatment efficiency and minimise the dose to the normal tissues. Radiation exposure in the out-of-field volumes arises from secondary neutrons and photons, particle fragments, and photons from activated materials. These unavoidable doses should be considered from the standpoint of radiological protection of the patient. Radiological protection of medical staff at ion beam therapy facilities requires special attention. Appropriate management and control are required for the therapy equipment and also for the air in the treatment room which can be activated by the particle beam and its secondaries. Radiological protection and safety management should always be in conformity with regulatory requirements. The current regulations for occupational exposures in photon radiotherapy are applicable to ion beam radiotherapy with protons or carbon ions. Ion beam radiotherapy requires, however, a more complex treatment system than conventional radiotherapy, and appropriate training of the staff and suitable quality assurance programme are recommended to avoid possible accidental exposure to the patient, to minimise unnecessary doses to normal tissues and to minimise radiation exposure of staff.

Here is an informative book that provides theoretical perspectives on the study of fetal movement and introduces observational assessments that can be used in fetal research. It provides research tools that can be used to delineate early patterns of movement, preparing therapists for neonatal intervention and leading to a better understanding of functional activity of the fetus. Concepts in Fetal Movement Research describes various ideas in fetal development and contains original research on a variety of topics, including: the way in which events experienced in utero help neonatal interaction with parents inductive and deductive approaches to assessment development scapular movement activity/inactivity of the 12-20 week old fetus two different research tools for assessing fetal movement. future directions for research by physical therapists in collaboration with other researchersResearchers, clinicians, obstetricians, radiologists, sonographers, and neonatologists will all find this book full of helpful information. Concepts in Fetal Movement Research is an invaluable guide for both their research and their day-to-day work with patients.

In this report, the Commission provides updated guidance on radiological protection against radon exposure. The report has been developed considering the latest ICRP recommendations for the system of radiological protection, all available scientific knowledge about the risks of radon, and the experience gained by many organisations and countries in the control of radon exposure. The report describes the characteristics of radon exposure, covering sources and transfer mechanisms, the health risks associated with radon, and the challenges of managing radon exposure. The Commission recommends an integrated approach for controlling radon exposure, relying as far as possible on the management of buildings or locations in which radon exposure occurs, whatever the use of the building. This approach is based on the optimisation principle, and is graded reflecting the responsibilities of key stakeholders, notably in workplaces, and the intent of the national authorities to control radon exposure. The report also provides recommendations on managing radon exposure when workers' exposures are considered as occupational, and the appropriate requirements of the Commission should be applied.

Towards the end of this century we celebrate three great discoveries of the last one - of X-rays in 1895, of radioactivity in 1896 and of radium in 1898 - and recall the pioneering achievements that founded the new science of radiology and changed the face of medicine forever. Dr Mould's comprehensive centennial history makes a unique contribution to the telling of this entertaining story - in the unusual and accessible style of a 'radiological photograph album'. Over 700 historical illustrations, with full and informative captions, are supported by short introductory essays to blow the dust off our fascinating radiological past in an easily readable style. The focus of this book is on the historically more interesting earlier years - of discovery and invention, diagnosis and therapy, dosimetry, risk and protection. The photographic record is complemented by archival accounts of the pioneer scientists and physicians, and of their early patients, and is interspersed with a variety of radiological anecdotes. In the several chapters on diagnostic techniques, radiotherapy and nuclear medicine the history is nevertheless brought up to date so that the old methodologies may be contrasted with newer technologies. The medical theme is itself complemented by two interesting chapters on museum and industrial applications of radiography. The predominantly photographic presentation of this book is derived from the author's earlier but smaller A History of X-rays and Radium, no longer available yet still of enduring interest. Research has been based on original source material which is fully cited and the illustrations and text are comprehensively indexed for easy retrieval of the wide variety ofpeople, techniques, apparatus and examples featured throughout this radiological journey.

This richly illustrated, comprehensive guide will enable the reader to identify anatomy and ophthalmic disease as illustrated on optical coherence tomography (OCT). It is the most up-to-date atlas of OCT images, many of which have been obtained with the newer OCT technologies that offer excellent image quality and definition at a microscopic level. All of the major disease areas in ophthalmology are covered, including diabetic retinopathy, age-related macular degeneration, uveitis, glaucoma, retinal vascular disease, and genetic abnormalities, and further hot topics are also considered. The chapters are written by leading international ophthalmologists from famous academic centers, and the numerous high-quality OCT images ensure that the reader will easily be able to follow the key issues. This book, with its clinical emphasis, will have wide appeal for residents, fellows, and experienced practitioners in ophthalmology, as well as optometrists and medical students and graduates.

Gastrointestinal Imaging: Case Review, by Vincent Low, MD, FRANZCR, tests your ability to interpret a wide range of images seen in practice. The completely revised edition of this medical reference book in the popular Case Review Series features 200 cases organized by difficulty, making it ideal for quick reference and easy board review! Study effectively with content that mimics the new format of board exams as well as the everyday clinical experience - offering highly effective preparation for certification, recertification, and practice. Spend less time searching and more time learning with easy-to-navigate chapters focused on visual identification and diagnosis, and reorganized by degree of case difficulty and then by body part within each category. Stay current with the most recent findings and advancements in gastrointestinal radiology. Review 200 cases organized by level of difficulty, with multiple-choice questions, answers, and rationales that mimic the new format of certification and recertification exams. Effectively employ differential diagnosis procedures to distinguish among diseases and disorders with similar sonographic presentations. Alleviate exam anxiety and sharpen your clinical skills with visual guidance from entirely new high-quality, state-of-the-art images presenting a wide range of clinical situations. Challenge your knowledge of a full range of topics in gastrointestinal imaging with - 200 cases that mimic the new board format

Radiation Hormesis presents the only critical review of the effects of whole-body exposure to low doses of ionizing radiation in animals. This is a "must read" book for radiobiologists, health-conscious individuals, and serious environmentalists. Topics discussed include our radiation environment, radiation hormesis in cancer mortality, growth and development, reproduction and mutation, immunity, and cancer. Data is presented that indicates that low doses of ionizing radiation may actually be beneficial to human health. This information could invalidate the "zero thesis" and linear models used by most regulatory agencies. The implications regarding eliminating linear models and accepting radiation hormesis are also discussed.

Engage with the visual world of disease with this accessible introduction to molecular imaging. This book provides users of all levels with the characterization and measurement of biological processes on a cellular level, functioning within humans, and other living systems. This important new introduction to the field will enable the reader to recognize the major methods, modalities and varied applications of molecular imaging in an efficient and effective way. Featuring techniques from areas such as nuclear medicine, magnetic resonance spectroscopy, optical imaging, and nanotechnology, the book also covers the current movement towards precision medicine thereby driving exceptional hospital care, worldwide. Molecular Imaging provides valuable insight into the properties that improve patient diagnosis. Serving to inform experienced physicians, students, and beginners alike, this convenient introduction is tailored to an individual with the desire to effectively grasp the basic concepts of molecular imaging, under the constraints of a busy professional career.

Ultrasound continues to be one of the most important diagnostic tools in medicine and is used by a wide range of healthcare professionals across many applications. This book provides a practical, clinically relevant guide for all practitioners working in the field of abdominal ultrasound. Its aim is to enable the operator to maximize the diagnostic information and recognize the limitations of ultrasound scans. Accessible, step-by-step approach Covers the basic related anatomy, technique and ultrasound appearances together with the most common pathological processes Written at a level suitable for both students and practitionersThis new edition features: 4-colour figures throughout New chapters on 'Ultrasound in infectious diseases' and 'Safety and musculoskeletal disorders Expanded sections on the bowel, and Contrast agent techniques.

A unique case-based approach to learning how to interpret gastrointestinal images

"Gastrointestinal Imaging Cases" features more than 150 gastrointestinal cases grouped according to organ system. Emphasizing clinical application, each case includes presentation, findings, differential diagnosis, comments, pearls, and numerous images. The book offers an efficient, systematic, and visual approach to help you better understand gastrointestinal imaging and sharpen your diagnostic skills. Covering a wide range of general clinical topics of interest to practicing imaging clinicians, "Gastrointestinal Imaging Cases" covers the liver, biliary, pancreas, esophagus, gastroduodenal, small bowel, colorectal, and omentum, mesentry, abdominal wall, and peritoneum.

The book's easy-to-navigate organization is specifically designed for use at the workstation. The concise, quick-read text, numerous images, and helpful pearls speed and simplify the learning process.

FEATURES Organ-specific organization More than 975 multi-modality images More than 150 classic case presentations with a strong focus on differential diagnosis Covers a wide range of clinical topics Consistent chapter organization

ABOUT THE McGRAW-HILL RADIOLOGY SERIES

This series offers indispensable workstation reference material for the practicing radiologist. Within this series is a full range of practical, clinically relevant works that are divided into three categories: Patterns: Organized by modality, these books provide a pattern-based approach to constructing practical differential diagnoses. Variants: Structured by modality as well as anatomy, these graphic references aid the radiologist in reducing false positive rates. Cases: Classic case presentations with an emphasis on differential diagnoses and clinical context.

Interpreting an ECG correctly and working out what to do next can seem like a daunting task to the non-specialist, yet it is a skill that will be invaluable to any doctor, nurse, or paramedic when evaluating the condition of a patient.
Making Sense of the ECG has been written specifically with this in mind, and will help the student and more experienced healthcare practitioner to identify and answer crucial questions, including:
Are these abnormalities significant?
How to I distinguish between VT and SVT?
Has the patient had a myocardial infarction?
How do I measure the QT interval?
Should I refer this patient to a cardiologist?
This practical, easy-to-read and easy-to-remember guide to the ECG as a tool for diagnosis and management has been fully updated in its fourth edition to reflect the latest guidelines.

This book provides a comprehensive account of the role of echocardiography in patients with mitral valve disease. The normal echocardiographic anatomy of the mitral valve is first presented, and the applications of echocardiography in mitral valve disease are then covered in detail by experts from different subspecialties in cardiology. Topics include etiology, pathophysiology, diagnosis, assessment of severity, and role of echocardiography in percutaneous and surgical techniques. The highly readable text is supported by a wealth of color images obtained with 3D echocardiography, currently the gold standard for the evaluation of mitral valve disease. The interdisciplinary approach used in describing the diagnostic and therapeutic applications will make this book useful for the clinical cardiologist as well as the echocardiographer. It will allow cardiologists to advance their knowledge in the field and will serve as an excellent updating tool for professionals engaged in echocardiography and cardiac diagnostic imaging.

Radiology Illustrated: Gastrointestinal Tract is the second of two volumes designed to provide clear and practical guidance on the diagnostic imaging of abdominal diseases. The book presents approximately 300 cases with 1500 carefully selected and categorized illustrations of gastrointestinal tract diseases, along with key text messages and tables that will help the reader easily to recall the relevant images as an aid to differential diagnosis. Essential points are summarized at the end of each text message to facilitate rapid review and learning. Additionally, brief descriptions of each clinical problem are provided, followed by case studies of both common and uncommon pathologies that illustrate the roles of the different imaging modalities, including ultrasound, radiography, computed tomography, and magnetic resonance imaging.

This book provides a comprehensive overview of diagnostic imaging in infectious diseases. It starts with a general review of infectious diseases, including their classification, characteristics and epidemiology. In separate chapters, the authors then introduce the radionuclide imaging of 50 kinds of infectious diseases. Volume 1 covers 21 viral infections. Volume 2 has 29 chapters discussing 24 bacterial infections and 5 parasitic infections. Each disease is clearly illustrated using cases combined with high-quality computed tomography (CT) and magnetic resonance imaging (MRI). The book provides a valuable reference source for radiologists and doctors working in the area of infectious diseases.

Epileptogenic lesions are often small and do not change over time. Moreover, several genetically determined epilepsy syndromes exist, and by definition are not caused by underlying structural lesions. As a result of these circumstances, there is frequently a degree of uncertainty over whether an epileptogenic lesion is being overlooked or simply is not present. MRI can play an important role in resolving such uncertainty and localizing epileptogenic foci. This book aims to provide the clinical and imaging information required in order to decide whether an MRI scan is appropriate and whether it is likely to be sufficient to detect a lesion. The first part of the book presents background information on epilepsy and explains how to perform an MRI examination. Detailed attention is paid to functional MRI and post-processing, and the examination of subcategories of patients is also discussed. The second part of the book then documents the MRI findings obtained in the full range of epileptogenic lesions with the aid of high-quality images. Throughout, emphasis is placed on guiding the reader in the correct interpretation of the imaging findings. Both radiologists and referring physicians will find this book to be an indispensable guide to the optimal use of MRI in epilepsy.

This book provides a comprehensive overview of diagnostic imaging in infectious diseases. It starts with a general review of infection diseases, including their classification, characteristics and epidemiology. In separate chapters, the authors then introduce the radionuclide imaging of 50 kinds of infectious diseases. Volume 1 covers 21 viral infections. Volume 2 has 29 chapters discussing 24 bacterial infections and 5 parasitic infections. Each disease is clearly illustrated using cases combined with high-quality computed tomography (CT) and magnetic resonance imaging (MRI). The book provides a valuable reference source for radiologists and doctors working in the area of infectious diseases.

The book offers a comprehensive and up-to-date guide to the cutting edge arthroscopic transosseous techniques for the treatment of rotator cuff tears, which are gradually taking over from the common open surgical approach, defined as the gold standard for RCR. With the help of numerous figures, it presents step by step a novel all-arthroscopic anchorless transosseous suture technique that is less invasive and easier to perform. After discussing the etiopathogenesis, histopathology and radiological classification of rotator cuff tears, the book reviews all possible arthroscopic procedures and explores in detail suture management, describing single and double tunnel options. It also examines the complications and post-operative rehabilitation and imaging, while the closing chapter addresses the economic aspects of daily use. Intended primarily for arthroscopic surgeons interested in the field of shoulder joint repair, this exhaustive guide is also a valuable resource for residents and shoulder specialists.

This comprehensive book describes in detail how nuclear medicine and radiology can meet the needs of the sports medicine physician by assisting in precise diagnosis, clarification of pathophysiology, imaging of treatment outcome and monitoring of rehabilitation. Individual sections focus on nuclear medicine and radiologic imaging of injuries to the head and face, spine, chest, shoulder, elbow and forearm, wrist and hand, pelvic region, knee, lower leg, ankle and foot. The pathophysiology of sports injuries frequently encountered in different regions of the body is described from the perspective of each specialty, and the potential diagnostic and management benefits offered by the new hybrid imaging modalities - SPECT/CT, PET/CT, and PET/MRI - are explained. In addition, a range of basic and general issues are addressed, including imaging of the injuries characteristic of specific sports. It is hoped that this book will promote interdisciplinary awareness and communication and improve the management of injured recreational or elite athletes.