The second edition of Spectral Domain OCT is a practical guide to the investigation and diagnosis of retinal disease using the Topcon machine. Beginning with an overview of OCT, the book provides a step by step approach to image capture, analysis and interpretation. With the help of numerous case studies, OCT patterns in different types of retinal disease are ppresented as both 2D and 3D images. In addition, Spectral Domain OCT highlights features of the new Topcon 2000 machine with an enhanced speed of 27,000 A scans/second, improved software algorithms and extra facilities for anterior segment imaging.

Diffusion-weighted MR Imaging, Perfusion MR Imaging, and Diffusion Tensor Imaging provide information that is present in no other imaging modality. With Guest Editor Scott Reeder focusing on the body and Guest Editor Pratik Mukerjee exploring the neurological aspects of these three imaging modalities, this is a must-have resource for any radiologist involved in MR Imaging. It explores such subjects as: Diffusion weighted MR imaging in musculoskeletal radiology, Arterial Spin Labeled Perfusion Imaging, and Diffusion Tensor Imaging of Neurodegenerative Diseases.

New radiotracers will make possible the imaging of other parts of the body using PET. This issue reviews the latest advances and provides a look to the future of PET imaging.

Now that the applications of positron emission tomography (PET) are becoming more clearly understood, PET is now being used in pediatric population. Important considerations in its use on children are patient preparation and radiation exposure. This issue reviews the use of PET to image children with Hodgkin and non-Hodgkin lymphoma, brain tumors, and inflammatory bowel disease, among other conditions. Also included is the use of PET to assess response to therapy.

This issue takes a multimodality approach to imaging of osteoarthritis. Clinical issues including an overview of the disease and imaging as an aid to evaluate patient functionality are also reviewed. Not only are current standards for imaging covered but also newer techniques under development.

With the advent of combined modality imaging, it has become essential for the radiologists how structure and function relate to each other. Previously radiologists had to rely upon CT or MRI in order to tell the location of a problem but could not assess functionally what was going on within the patient. PET image has allowed radiologists to make a functional assessment to aid in the diagnosis and treatment planning for patients. This issue reviews the use of PET/CT and PET/MRI to evaluate patients with neurologic disorders, malignant and nonmalignant thoracic disorders, the cardiovascular system, breast diseases, musculoskeletal system, abdominal and pelvic disorders, and endocrine disorders.

Topics include: MR Imaging of the Pediatric Bone Marrow; The growing skeleton: MR appearances of developing cartilage; Infectious and Inflammatory Disorders; MRI of Pediatric Trauma; MRI of Pediatric Arthritis; MR Imaging of Primary Bone Tumors and Tumor-like Conditions in Children; MR Imaging of soft tissue masses in children; The hip: MR imaging of uniquely pediatric disorders; The knee: MR imaging of uniquely pediatric disorders; The foot and ankle: MR imaging of uniquely pediatric disorders; MRI in Congenital and Acquired Disorders of the Pediatric Upper Extremity.

A detailed description of up-to-date methods used for computer processing and interpretation of medical images is given. The scope of the book include images acquisition, storing with compression, processing, analysis, recognition and also its automatic understanding In introduction general overview of the computer vision methods designed for medical images is presented. Next sources of medical images are presented with their general characteristics. Both traditional (like X-ray) and very modern (like PET) sources of medical images are presented. The main emphasis is placed on such properties of medical images given by particular medical imaging methods which are important form the point of view of its computer processing, analysis and recognition. The consecutive parts of the book describe compression and processing methods, including many methods developed by authors especially for medical images. After parts describing analysis and recognition of medical images come most important part, in which the new method of automatic understanding of medical images is given. This new method of image interpretation, described in previous works of the same authors with applications for simple 2D images now is generalized for 3D images and for complex medical images with many objects observed and with complicated relations between these objects.

This issue takes a survey approach to the role of imaging of the musculoskeletal system. Starting with the role of conventional radio graphs, all modalities including MR, CT, ultrasound, and nuclear medicine are reviewed, as well as interventional applications, such as arthrography, radio frequency, and cryoablation of tumors.

Forensic anthropology deals with human remains usually in the skeletonized form. The application of microscopy to skeletal tissues is well established and used routinely in biomedical science. Its adaptation to forensic questions is an increasing area of interest, and publications utilizing microscopy have increased in the scientific literature. In Forensic Microscopy for Skeletal Tissues: Methods and Protocols, expert researchers in the forensic, archeological and paleontological disciplines, and detail many of the methods which are now commonly used to study skeletal material. These methods include differing forms of light, confocal, scanning electron and transmission electron microscopy. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Forensic Microscopy for Skeletal Tissues: Methods and Protocols bring together differing forms of microscopy that are used in association with forensic anthropology, or have relevance to questions concerning forensic anthropology.

Because of their constant use and intricate architecture, the foot and ankle can be the source of many problems. As a result, imaging is crucial for diagnostic purposes and so that treatment decisions can be made. This issue reviews imaging of soft-tissue lesions, osteochondral lesions, and metatarsalgia. Sonography of the hind and mid foot, Imaging of Lis Franc injury, and imaging of the diabetic pedal osteomyelitis are also covered among other topics.

MRI in Practice continues to be the number one reference book and study guide for the registry review examination for MRI offered by the American Registry for Radiologic Technologists (ARRT). This latest edition offers in-depth chapters covering all core areas, including: basic principles, image weighting and contrast, spin and gradient echo pulse sequences, spatial encoding, k-space, protocol optimization, artefacts, instrumentation, and MRI safety. The leading MRI reference book and study guide. Now with a greater focus on the physics behind MRI. Offers, for the first time, equations and their explanations and scan tips. Brand new chapters on MRI equipment, vascular imaging and safety. Presented in full color, with additional illustrations and high-quality MRI images to aid understanding. Includes refined, updated and expanded content throughout, along with more learning tips and practical applications. Features a new glossary. MRI in Practice is an important text for radiographers, technologists, radiology residents, radiologists, and other students and professionals working within imaging, including medical physicists and nurses.

This volume addresses the various techniques and novel applications of mass spectrometry imaging (MSI) and its role as a discovery tool in the field of proteomics, lipidomics, and metabolomics. The chapters in this book demonstrate how MSI can be applied to many areas of research such as clinical pathology, translational medicine, toxicology, biomarkers and response studies, and potential incorporation of MSI into forensic workflows. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Innovative and comprehensive, Imaging Mass Spectrometry: Methods and Protocols is a valuable resource for research scientists and clinicians who are interested in further studies of MSI technologies.

This book covers all the existing imaging modalities currently in use in imaging departments, providing a sound basis for understanding how individual systems work. It is designed to be accessible to students without minimising the content. Although conventional imaging is being phased out, it still exists in certain areas, e.g. dental surgeries, and therefore is reduced in size and placed in an Appendix. The text has been restructured in list form to increase clarity and aid study Pedagogic features include an introduction and summary for each chapter Glossaries of imaging terms and computer buzz words, and a key to commonly used abbreviations are included New edition is completely rewritten: Digital imaging is main focus CT, ultrasound, MRI and NMR imaging added 'Conventional' imaging retained as an Appendix Text simplified, and block diagrams, flow charts and tables added to increase accessibility of content

This book provides a complete overview of all modalities used for hand and wrist imaging, along with a complete overview of the various disease entities that can be diagnosed. As a state-of-the-art overview of hand and wrist imaging it is a reference work for radiologists, hand surgeons, orthopedists, traumatologists, rheumatologists and internists and their residents in training. The chapters are written by experts in musculoskeletal radiology from various European countries and the USA.

As a spectroscopic method, Nuclear Magnetic Resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Acids" and "NMR of Carbohydrates, Lipids and Membranes." For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an in valuable source of current methods and applications. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.

Medical Imaging Informatics provides an overview of this growing discipline, which stems from an intersection of biomedical informatics, medical imaging, computer science and medicine. Supporting two complementary views, this volume explores the fundamental technologies and algorithms that comprise this field, as well as the application of medical imaging informatics to subsequently improve healthcare research. Clearly written in a four part structure, this introduction follows natural healthcare processes, illustrating the roles of data collection and standardization, context extraction and modeling, and medical decision making tools and applications.

Medical Imaging Informatics identifies core concepts within the field, explores research challenges that drive development, and includes current state-of-the-art methods and strategies.

This book represents volume 2 of a 3-volume monograph on Particle Penetration and Radiation Effects. While volume 1 addressed the basic theory of scattering and stopping of swift point charges, i.e., protons, antiprotons and alpha particles, the present volume focuses on ions heavier than helium as well as molecules and clusters over an energy range from a few keV/u to a few hundred MeV/u. The book addresses the foundations in atomic-collision physics of a wide variety of application areas within materials and surface science and engineering, micro and nano science and technology, radiation medicine and biology as well as nuclear and particle physics. Problems have been added to all chapters. This should make the book useful for both self-study and advanced university courses. An effort has been made to establish a unified notation throughout the monograph.