Clinical Microbiology, Volume 664 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Synthesis of chemical probes to study bacterial adenylating enzymes, Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux, Combining informatics with ABPP to identify serine hydrolyses in bacteria, A Ligand Selection Strategy Identifies Chemical Probes Targeting the Proteases of SARS-CoV-2, Activity-based probes for bacterial histidine kinases, Metabolomic approaches to enzyme function and pathway discovery, Identification of bile salt hydrolase activity in gut microbiota, and much more. Other chapters cover Multiplex fluorescence screening and identification using multiplex TMT, Customized Peptidoglycan Surfaces to Investigate Innate Immune Recognition via SPR, Site-Specific Siderocalin Binding to Ferric and Ferric-Free Enterobactin As Revealed by Mass Spectrometry, Proteomics of short-chain fatty acid probes in Salmonella, Development and application of highly sensitive labeling reagents for amino acids, and a variety of other timely topics.

Green Sustainable Process for Chemical and Environmental Engineering and Science: Biomedical Application of Biosurfactant in Medical Sector highlights the numerous applications of biosurfactants in the field of medicine, especially as a replacement to synthetic drugs which have developed several levels of resistance over the years. Special emphasis is laid on their application as non-pyrogenic and non-toxic immunological adjuvants and their inhibitory characteristics against H+, K+, -ATPase and defense against gastric ulcers, along with their practical application as anti-adhesive coating agents for medical insert materials. The book addresses issues by combining knowledge of their production with information on a range of medical applications. Drawing on the knowledge of its expert team of global contributors, this book provides useful insights for all those currently or potentially interested in developing or applying biosurfactants in their own work.

Petroleum Industry Wastewater: Advanced and Sustainable Treatment Methods discusses the status of different approaches and advanced processes involved in the treatment of petrochemical and petroleum industry wastewater. The book focuses on advanced, sustainable, and environmentally friendly technologies for removing toxic pollutants from contaminated waters. The book also explores the environmental aspects and impacts of the petroleum industry discharge wastewater, their effect on aquatic life, and possible ways to deal with these effects. Keeping the global water crisis and fast depletion of natural fresh water in mind, more immediate knowledge, information, implication, and effective utilization of available resources are required than we anticipated. The book brings a wide range of methodologies and perspectives under one roof in a comprehensive manner.

Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2. In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization.

Development in Wastewater Treatment Research and Processes: Microbial Degradation of Xenobiotics through Bacterial and Fungal Approach covers the active and applicable role that bacteria and fungi play in the degradation of xenobiotic compounds from the environment. The book gives up-to-date information on recent advancements in the field of environmental xenobiotics and how they disturb a plant's metabolism. The book also gives information on aerobic and anaerobic degradation of xenobiotic compounds through bacteria or fungi and/or a combined approach. Finally, the book covers the characteristics of environmental microbiology, biochemical engineering, agricultural microbiology, environmental engineering, and soil bioremediation.

Advancements in Polymer-Based Membranes for Water Remediation describes the advanced membrane science and engineering behind the separation processes within the domain of polymer-based membrane systems in water remediation. Emphasis has been put on several aspects, ranging from fundamental concepts to the commercialization of pressure and potential driven membranes, updated with the latest technological progresses, and relevant polymer materials and application potential towards water treatment systems. Also included in this book are advances in polymers for membrane application in reverse osmosis, nanofiltration, ultrafiltration, microfiltration, forward osmosis, and polymeric ion-exchange membranes for electrodialysis and capacitive deionization. With its critical analyzes and opinions from experts around the world, this book will garner considerable interest among actual users, i.e., scientists, engineers, industrialists, entrepreneurs and students.

Advances in Oil-Water Separation: A Complete Guide for Physical, Chemical, and Biochemical Processes discusses a broad variety of chemical, physical and biochemical processes, including skimming, membrane separation, adsorption, onsite chemical reactions, burning and usage of suitable microbial strains for onsite degradation of oil. It critically reviews all current developments in oil-water separation processes and technologies, identifies gaps and illuminates the scope for future research and development in the field. This book provides researchers, engineers and environmental professionals working in oil recovery and storage with solutions for disposal of waste oil and separation of oil from water in a sustainable, environmentally-friendly way. As the book provides a complete state-of-art overview on oil-water separation technologies, it will also ease literature searches on oil-water separation technologies.

Advances in Cancer Research, volume 153 provides a timely review of the biology, biochemistry, and current approaches to therapeutically target the RAS oncoprotein, the most frequently mutated oncogene family in human cancers. 2021 saw the approval of the first direct RAS inhibitor (sotorasib) for use in treating non-small cell lung cancers harboring KRAS(G12C) mutations. The successful approval and use of this drug highlights that the once "undruggable" RAS is indeed pharmacologically tractable. This volume provides an overview of efforts to develop additional approaches to therapeutically target oncogenic RAS. In addition, the reader will find excellent reviews on the history and research efforts to understand the biochemistry and oncogenic activity of RAS in human cancers.

Microbiome Under Changing Climate: Implications and Solutions presents the latest biotechnological interventions for the judicious use of microbes to ensure optimal agricultural yield. Summarizing aspects of vulnerability, adaptation and amelioration of climate impact, this book provides an important resource for understanding microbes, plants and soil in pursuit of sustainable agriculture and improved food security. It emphasizes the interaction between climate and soil microbes and their potential role in promoting advanced sustainable agricultural solutions, focusing on current research designed to use beneficial microbes such as plant growth promoting microorganisms, fungi, endophytic microbes, and more. Changes in climatic conditions influence all factors of the agricultural ecosystem, including adversely impacting yield both in terms of quantity and nutritional quality. In order to develop resilience against climatic changes, it is increasingly important to understand the effect on the native micro-flora, including the distribution of methanogens and methanotrophs, nutrient content and microbial biomass, among others.

Advances in Dairy Microbial Products describes the importance and utility of microbial products used in dairy products. This book explains the makeup of these products in a scientifically sound yet simple manner. The appeal of this book is its holistic approach to addressing the different aspects of the dairy industry, from basic dairy microbial biochemistry to production of dairy products and their nutrient quality, and finally to machine learning applications in dairy industry. Comprised of chapters written and edited by international authorities and researchers with top expertise in dairy products, it offers both established and cutting-edge solutions to the numerous challenges commonly encountered in the industrial processing of milk and the production of milk products. This book offers a highly practical approach to the topic, addressing and tackling the problems faced in the workplace by dairy technologists. Researchers and practitioners will find this book to be an ideal source of thorough and up-to-date information on dairy microbial products while also appealing to beginners seeking to understand how advanced dairy technologies can increase the efficiency of current techniques.

The Microbiology of Central Nervous System Infections, Volume 3, discusses modern approaches to the diagnosis, treatment and prophylaxis of central nervous system (CNS) infections. This new release is divided into five sections that cover treatment strategies, imaging, molecular diagnosis, management of CNS infections with metal nanoparticles, and prophylaxis of CNS infections, including bacterial, viral and fungal infections. The last section contains a chapter on transmissible spongiform encephalopathies and modern trends in its diagnosis and treatment. University teachers, medical practitioners, graduate and postgraduate students, researchers in microbiology, and those in the pharmaceutical and laboratory diagnostic industries will find the book very important.

Microbiological Analysis of Foods and Food Processing Environments is a well-rounded text that focuses on food microbiology laboratory applications. The book provides detailed steps and effective visual representations with microbial morphology that are designed to be easily understood. Sections discuss the importance of the characteristics of microorganisms in isolation and enumeration of microorganisms. Users will learn more about the characteristics of microorganisms in medicine, the food industry, analysis laboratories, the protection of foods against microbial hazards, and the problems and solutions in medicine and the food industry. Food safety, applications of food standards, and identification of microorganisms in a variety of environments depend on the awareness of microorganisms in their sources, making this book useful for many industry professionals.

Many physico-chemical and operational factors influence the performance, treatment costs and long-term stability of biofilters for the treatment of wastewater. An Innovative Role of Biofiltration in Wastewater Treatment Plants focuses on identifying the factors that affect biofiltration, such as the hydraulic retention time of the biofiltration system, the type and characteristics of the filter and the attached biomass, explains their influence and provides guidelines on how to control these factors to optimize better operation with respect to pollutant control present in wastewater treatment plants (WWTPs). The fundamental basis of treatment in biofilters is the action of pollutant-degrading microorganisms and consequently the book also discusses in depth about the microbial ecology of biofiltration. In addition, it explores the applications of biofiltration including the removal of emerging pollutants.

Microbial Biodegradation and Bioremediation: Techniques and Case Studies for Environmental Pollution, Second Edition describes the successful application of microbes and their derivatives for bioremediation of potentially toxic and relatively novel compounds in the environment. Our natural biodiversity and environment is in danger due to the release of continuously emerging potential pollutants by anthropogenic activities. Though many attempts have been made to eradicate and remediate these noxious elements, thousands of xenobiotics of relatively new entities emerge every day, thus worsening the situation. Primitive microorganisms are highly adaptable to toxic environments, and can reduce the load of toxic elements by their successful transformation and remediation. This completely updated new edition presents many new technologies and techniques and includes theoretical context and case studies in every chapter. Microbial Biodegradation and Bioremediation: Techniques and Case Studies for Environmental Pollution, Second Edition serves as a single-source reference and encompasses all categories of pollutants and their applications in a convenient, comprehensive format for researchers in environmental science and engineering, pollution, environmental microbiology, and biotechnology.

Advances in Microbial Physiology, Volume 79, the latest release in this serial that highlights new advances in the field, presents interesting and timely chapters authored by an international board of subject matter experts.

Advances in Applied Microbiology, Volume 117 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology.

Advances in Virus Research, Volume 111, the latest release in a serial that highlights new advances in the field, presents interesting and timely chapters authored by an international board of subject matter experts.

Removal of Emerging Contaminants from Wastewater through Bio-nanotechnology showcases profiles of the nonregulated contaminants termed as "emerging contaminants," which comprise industrial and household persistent toxic chemicals, pharmaceuticals and personal care products (PPCPs), pesticides, surfactants and surfactant residues, plasticizers and industrial additives, manufactured nanomaterials and nanoparticles, microplastics, etc. that are used extensively in everyday life. The occurrence of "emerging contaminants" in wastewater, and their behavior during wastewater treatment and production of drinking water are key issues in the reuse and recycling of water resources. This book focuses on the exploitation of Nano-biotechnology inclusive of the state-of-the-art remediate strategies to degrade/detoxify/stabilize toxic and hazardous contaminants and restore contaminated sites, which is not as comprehensively discussed in the existing titles on similar topics available in the global market. In addition, it discusses the potential environmental and health hazards and ecotoxicity associated with the widespread distribution of emerging contaminants in the water bodies. It also considers the life cycle assessment (LCA) of emerging (micro)-pollutants with suitable case studies from various industrial sources.

An Integration of Phycoremediation Processes in Wastewater Treatment reviews the potential of microalgae to treat wastewater containing highly recalcitrant compounds whose degradation is not achieved by the conventional existing treatments. In addition, the book describes how the microalgae collected after wastewater treatment can be used for obtaining added-value products, hence closing the loop and contributing to a circular economy. Finally, the technoeconomical aspects of this green technology are addressed, along with the design and development of photobioreactors, genetic aspects, metagenomics and metabolomics.

Tackling the issue of water and wastewater treatment nowadays requires novel approaches to ensure that sustainable development can be achieved. Water and wastewater treatment should not be seen only as an end-of-pipe solution but instead the approach should be more holistic and lead to a more sustainable process. This requires the integration of various methods/processes to obtain the most optimized design. Integrated and Hybrid Process Technology for Water and Wastewater Treatment discusses the state-of-the-art development in integrated and hybrid treatment processes and their applications to the treatment of a vast variety of water and wastewater sources. The approaches taken in this book are categorized as (i) resources recovery and consumption, (ii) optimal performance, (iii) physical and environmental footprints, (iv) zero liquid discharge concept and are (v) regulation-driven. Through these categories, readers will see how such an approach could benefit the water and wastewater industry. Each chapter discusses challenges and prospects of an integrated treatment process in achieving sustainable development. This book serves as a platform to provide ideas and to bridge the gap between laboratory-scale research and practical industry application.

Microbes in Land Use Change Management details the various roles of microbial resources in management of land uses and how the microbes can be used for the source of income due to their cultivation for the purpose of biomass and bioenergy production. Using various techniques, the disturbed and marginal lands may also be restored eco-friendly in present era to fulfil the feeding needs of mankind around the globe. Microbes in Land Use Change Management provides standard and up to date information towards the land use change management using various microbial technologies to enhance the productivity of agriculture. Needless to say that Microbes in Land Use Change Management also considers the areas including generation of alternative energy sources, restoration of degraded and marginal lands, mitigation of global warming gases and next generation -omics technique etc. Land use change affects environment conditions and soil microbial community. Microbial population and its species diversity have influence in maintaining ecosystem balance. The study of changes of microbial population provides an idea about the variation occurring in a specific area and possibilities of restoration. Meant for a multidisciplinary audience Microbes in Land Use Change Management shows the need of next-generation omics technologies to explore microbial diversity.

Advances in Cancer Research, Volume 152, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.

Advances in Applied Microbiology, Volume 116 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology, with this release focusing on the lipid production by oleaginous yeasts.