Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine sheds new light on various applications of microbial metabolites in the biomedical sector. The purpose of this book is to integrate the latest research advancements on the application of microbial metabolites in the medical industry into a single platform. In 10 chapters, the significance of biomedical applications and future therapeutic applications of microbial metabolites in human health are highlighted. Several chapters are dedicated to the role of microbial metabolites in precision medicine like the impact of the activities of microbial metabolites in antitumor and antidiabetic agents and immunosuppressive activities. It also provides a roadmap for drugs discovery based on antimicrobial products and the effect of microbial metabolites on humans' health and the immune system. The book finalizes with a chapter on the use of microbial metabolites in OMICS technology. Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine targets researchers from both academia and industry, professors, and graduate students from microbiology, molecular biology, biotechnology, and immunology.

Advancements in Polymer-Based Membranes for Water Remediation describes the advanced membrane science and engineering behind the separation processes within the domain of polymer-based membrane systems in water remediation. Emphasis has been put on several aspects, ranging from fundamental concepts to the commercialization of pressure and potential driven membranes, updated with the latest technological progresses, and relevant polymer materials and application potential towards water treatment systems. Also included in this book are advances in polymers for membrane application in reverse osmosis, nanofiltration, ultrafiltration, microfiltration, forward osmosis, and polymeric ion-exchange membranes for electrodialysis and capacitive deionization. With its critical analyzes and opinions from experts around the world, this book will garner considerable interest among actual users, i.e., scientists, engineers, industrialists, entrepreneurs and students.

Removal of Emerging Contaminants from Wastewater through Bio-nanotechnology showcases profiles of the nonregulated contaminants termed as "emerging contaminants," which comprise industrial and household persistent toxic chemicals, pharmaceuticals and personal care products (PPCPs), pesticides, surfactants and surfactant residues, plasticizers and industrial additives, manufactured nanomaterials and nanoparticles, microplastics, etc. that are used extensively in everyday life. The occurrence of "emerging contaminants" in wastewater, and their behavior during wastewater treatment and production of drinking water are key issues in the reuse and recycling of water resources. This book focuses on the exploitation of Nano-biotechnology inclusive of the state-of-the-art remediate strategies to degrade/detoxify/stabilize toxic and hazardous contaminants and restore contaminated sites, which is not as comprehensively discussed in the existing titles on similar topics available in the global market. In addition, it discusses the potential environmental and health hazards and ecotoxicity associated with the widespread distribution of emerging contaminants in the water bodies. It also considers the life cycle assessment (LCA) of emerging (micro)-pollutants with suitable case studies from various industrial sources.

An Integration of Phycoremediation Processes in Wastewater Treatment reviews the potential of microalgae to treat wastewater containing highly recalcitrant compounds whose degradation is not achieved by the conventional existing treatments. In addition, the book describes how the microalgae collected after wastewater treatment can be used for obtaining added-value products, hence closing the loop and contributing to a circular economy. Finally, the technoeconomical aspects of this green technology are addressed, along with the design and development of photobioreactors, genetic aspects, metagenomics and metabolomics.

Advances in Cancer Research, volume 153 provides a timely review of the biology, biochemistry, and current approaches to therapeutically target the RAS oncoprotein, the most frequently mutated oncogene family in human cancers. 2021 saw the approval of the first direct RAS inhibitor (sotorasib) for use in treating non-small cell lung cancers harboring KRAS(G12C) mutations. The successful approval and use of this drug highlights that the once "undruggable" RAS is indeed pharmacologically tractable. This volume provides an overview of efforts to develop additional approaches to therapeutically target oncogenic RAS. In addition, the reader will find excellent reviews on the history and research efforts to understand the biochemistry and oncogenic activity of RAS in human cancers.

Oncogenic Viruses: Fundamentals of Oncoviruses provides an overview of the history of human oncoviruses, how to discover and define an oncovirus, how viruses cause cancer in general, their oncogenic mechanisms and epidemiology, and the cancer biology of oncoviruses. The book is organized into five main parts that include history and discovery of virus-tumor complications, taxonomy and classification of oncoviruses, oncoviruses around the world, including epidemiology statistics and current methods. Finally, the book looks at the molecular epidemiology of DNA and RNA viruses and their role in the pathogenesis of human cancers.

Microbes in Land Use Change Management details the various roles of microbial resources in management of land uses and how the microbes can be used for the source of income due to their cultivation for the purpose of biomass and bioenergy production. Using various techniques, the disturbed and marginal lands may also be restored eco-friendly in present era to fulfil the feeding needs of mankind around the globe. Microbes in Land Use Change Management provides standard and up to date information towards the land use change management using various microbial technologies to enhance the productivity of agriculture. Needless to say that Microbes in Land Use Change Management also considers the areas including generation of alternative energy sources, restoration of degraded and marginal lands, mitigation of global warming gases and next generation -omics technique etc. Land use change affects environment conditions and soil microbial community. Microbial population and its species diversity have influence in maintaining ecosystem balance. The study of changes of microbial population provides an idea about the variation occurring in a specific area and possibilities of restoration. Meant for a multidisciplinary audience Microbes in Land Use Change Management shows the need of next-generation omics technologies to explore microbial diversity.

Advances in Microbial Physiology, Volume 79, the latest release in this serial that highlights new advances in the field, presents interesting and timely chapters authored by an international board of subject matter experts.

Advances in Applied Microbiology, Volume 117 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology.

Advances in Virus Research, Volume 111, the latest release in a serial that highlights new advances in the field, presents interesting and timely chapters authored by an international board of subject matter experts.

Microbial Biodegradation and Bioremediation: Techniques and Case Studies for Environmental Pollution, Second Edition describes the successful application of microbes and their derivatives for bioremediation of potentially toxic and relatively novel compounds in the environment. Our natural biodiversity and environment is in danger due to the release of continuously emerging potential pollutants by anthropogenic activities. Though many attempts have been made to eradicate and remediate these noxious elements, thousands of xenobiotics of relatively new entities emerge every day, thus worsening the situation. Primitive microorganisms are highly adaptable to toxic environments, and can reduce the load of toxic elements by their successful transformation and remediation. This completely updated new edition presents many new technologies and techniques and includes theoretical context and case studies in every chapter. Microbial Biodegradation and Bioremediation: Techniques and Case Studies for Environmental Pollution, Second Edition serves as a single-source reference and encompasses all categories of pollutants and their applications in a convenient, comprehensive format for researchers in environmental science and engineering, pollution, environmental microbiology, and biotechnology.

A Complete Guidebook on Biofilm Study has emphasized the biofilm-related issues in the present context related to research and development. For this purpose, experimental design and relevant experimental protocols for the biofilm studies have been highlighted here. In addition to that, inhibitors from natural or synthetic sources against microbial biofilm development have been addressed. This approach has been further substantiated by bioinformatics as well as nanotechnology-based reports. Both, the image processing related to biofilm study and the characters of substratum associated with biofilm development have also been included for a better understanding of the beginners in this field. Further, how biofilm helps and/or hampers in food processing and waste management system, that discussion has been considered in this book. Similarly, human benefits from biofilm and reverse of it have also been included considering host-pathogen interaction, immunity aspects, and others.

The Future of Effluent Treatment Plants: Biological Treatment Systems is an advanced and updated version of existing biological technologies that includes their limitations, challenges, and potential application to remove chemical oxygen demand (COD), refractory chemical oxygen demand, biochemical oxygen demand (BOD), color removal and environmental pollutants through advancements in microbial bioremediation. The book introduces new trends and advances in environmental bioremediation with thorough discussions of recent developments. In addition, it illustrates that the application of these new emerging innovative technologies can lead to energy savings and resource recovery. The importance of respiration, nitrogen mineralization, nitrification, denitrification and biological phosphorus removal processes in the development of a fruitful and applicable solution for the removal of toxic pollutants from wastewater treatment plants is highlighted. Equally important is the knowledge and theoretical modeling of water movement through wastewater ecosystems. Finally, emphasis is given to the function of constructed wetlands and activated sludge processes.

Wastewater Treatment Reactors: Microbial Community Structure analyzes microbial community structure in relation to changes in physico-chemical parameters, the gene content (metagenome) or gene expression (metatranscriptome) of microbial communities in relation to changes in physico-chemical parameters, physiological aspects of microbial communities, enrichment cultures or pure cultures of key species in relation to changes in physico-chemical parameters, and modeling of potential consequences of changes in microbial community structure or function for higher trophic levels in a given habitat. As several studies have been carried out to understand bulking phenomena and the importance of environmental factors on sludge settling characteristics, which are thought to be strongly influenced by flocculation, sludge bulking, foaming and rising, this book is an ideal resource on the topics covered.

Lactic Acid Bacteria in Food Biotechnology: Innovations and Functional Aspects describes the latest advancements in LAB applications in the development of functional foods and fermented foods, biotechnological products using LAB, i.e., bio chemicals (organic acids, bacteriocins, etc.), bioactive and functional biomolecules, comparative genomics of probiotic LAB, and genetically modified LAB in food industry. Bridging the gap between LAB-mediated fermented foods and bioactive compounds, vis-a-vis molecular aspects, this book enables the transition from research to application. The book details applications of LAB in fermented/functional foods including cereals, vegetables, fish, meat cheese, other dairy products, and much more. Other sections cover their biochemistry and biotechnology aspects, bio preservation by bio molecules produced by LAB, bioactive metabolites and biosurfactants, including their value in health and wellness and exploring the genomics of LAB from food to health. Finally, the book addresses genetically modified lactic acid bacteria in food and beverages.

Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Advances in Cancer Research, Volume 152, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.

Advances in Applied Microbiology, Volume 116 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology, with this release focusing on the lipid production by oleaginous yeasts.

Stromal Signaling in Cancer, Volume 154 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics surrounding cancer research. Each chapter is written by an international board of authors.

Microbiome Stimulants for Crops: Mechanisms and Applications provides the latest developments in the real-world development and application of these crop management alternatives in a cost-effective, yield protective way. Sections address questions of research, development and application, with insights into recent legislative efforts in Europe and the United States. The book includes valuable information regarding mechanisms and the practical information needed to support the growing microbial inoculant and biostimulant industry, thus helping focus scientific research in new directions.

Tackling the issue of water and wastewater treatment nowadays requires novel approaches to ensure that sustainable development can be achieved. Water and wastewater treatment should not be seen only as an end-of-pipe solution but instead the approach should be more holistic and lead to a more sustainable process. This requires the integration of various methods/processes to obtain the most optimized design. Integrated and Hybrid Process Technology for Water and Wastewater Treatment discusses the state-of-the-art development in integrated and hybrid treatment processes and their applications to the treatment of a vast variety of water and wastewater sources. The approaches taken in this book are categorized as (i) resources recovery and consumption, (ii) optimal performance, (iii) physical and environmental footprints, (iv) zero liquid discharge concept and are (v) regulation-driven. Through these categories, readers will see how such an approach could benefit the water and wastewater industry. Each chapter discusses challenges and prospects of an integrated treatment process in achieving sustainable development. This book serves as a platform to provide ideas and to bridge the gap between laboratory-scale research and practical industry application.

The book Methods in Silkworm Microbiology is the first ever publication that provides in-depth reviews on the latest progresses about silkworm -pathogen interactions, diseases and management practices for sustainable development of sericulture. Different molecular and immunodiagnostic methods for the detection of pathogens have been comprehensively addressed. Most recent advancements on the role of Micro RNAs in silkworm and pathogen interactions are provided with suitable illustrations. Recent technological advances and emerging trends in exploring silkworm gut microbial communities towards translation research, particularly to understand microbiome functions have been highlighted. Information on various immune mechanisms of silkworm against invading pathogens is summarized. The book further highlights the silkworm gut microbiota as a potential source for biotechnological applications.

Development in Wastewater Treatment Research and Processes: Microbial Degradation of Xenobiotics through Bacterial and Fungal Approach covers the active and applicable role that bacteria and fungi play in the degradation of xenobiotic compounds from the environment. The book gives up-to-date information on recent advancements in the field of environmental xenobiotics and how they disturb a plant's metabolism. The book also gives information on aerobic and anaerobic degradation of xenobiotic compounds through bacteria or fungi and/or a combined approach. Finally, the book covers the characteristics of environmental microbiology, biochemical engineering, agricultural microbiology, environmental engineering, and soil bioremediation.