Mental illness and the variety of conditions, disorders, and phobias associated with it impact not only the individual but also the family unit, the community, and society at large. Handbook of Cognitive Behavioral Therapy by Disorder: Case Studies and Application for Adults will better readers' understanding of a variety of these conditions in adults specifically and the applicability of CBT therapy as a treatment. Featuring chapters on schizophrenia, bipolar disorder, dysmorphia, depression, and anxiety, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues in adults. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.

This book discusses the emergence of diverse functional organizations in the visual pathway which could be spontaneously and solely initiated by the random feedforward wiring of neural circuits. It demonstrates that the structure of ON and OFF retinal ganglion cell (RGC) mosaics is projected onto V1 by retino-cortical feedforward mapping to induce higher cognitive functions. This book will be beneficial for both theoretical and experimental neuroscientists, as well as for researchers using brain-inspired neural network models.

dance, data, multimodal communication, dancers, neuro-cognitive science, contemporary dance, intangible cultural heritage, performing arts, cognitive linguistics, embodiment, design, and creativity studies

This volume contains a comprehensive compilation of chromogenic and fluorescent RNA in situ hybridization (ISH) technology in many of its various shades, forms, and applications. The book is organized into a number of parts and chapters focusing on the application of ISH methodologies to different animal species as used in Evolutionary Development (EvoDevo) and Biomedical research, and covering new developments in RNA visualization by fluorescent ISH (FISH). The described (F)ISH protocols employ effective strategies for signal enhancement and target amplification allowing for high signal intensities and drastically improved signal-to-noise ratios. Chromogenic and fluorescent ISH, as specified in the various chapters, are most essential for RNA expression profiling, applied to many fields of research including cellular, developmental, and evolutionary biology, neurobiology and neuropathology. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Essential and authoritative, In Situ Hybridization Methods provides detailed protocols for newcomers to ISH, and inspires researchers familiar with the technique to seek and find up-to-date methodology for new and specialized applications.

One in four of us experience a mental health problem each year, with anxiety and depression alone affecting over 500 million people worldwide.

Why are these conditions so widespread? What is it about modern life that has such an impact on our mental health? And why is there still so much confusion and stigma around these issues?

In Psycho-Logical, neuroscientist and bestselling author Dean Burnett answers these questions and more, revealing what is actually going on in our brains when we suffer mental health issues such as anxiety, depression and addiction.

Combining illuminating scientific research with first-hand insights from people who deal with mental health problems on a daily basis, this is an honest, entertaining and reassuring account of how and why these issues occur, and how to make sense of them.

Auditory behavior, perception, and cognition are all shaped by information from other sensory systems. This volume examines this multi-sensory view of auditory function at levels of analysis ranging from the single neuron to neuroimaging in human clinical populations. Visual Influence on Auditory Perception Adrian K.C. Lee and Mark T. Wallace Cue Combination within a Bayesian Framework David Alais and David Burr Toward a Model of Auditory-Visual Speech Intelligibility Ken W. Grant and Joshua G. W. Bernstein An Object-based Interpretation of Audiovisual Processing Adrian K.C. Lee, Ross K. Maddox, and Jennifer K. Bizley Hearing in a "Moving" Visual World: Coordinate Transformations Along the Auditory Pathway Shawn M. Willett, Jennifer M. Groh, Ross K. Maddox Multisensory Processing in the Auditory Cortex Andrew J. King, Amy Hammond-Kenny, Fernando R. Nodal Audiovisual Integration in the Primate Prefrontal Cortex Bethany Plakke and Lizabeth M. Romanski Using Multisensory Integration to Understand Human Auditory Cortex Michael S. Beauchamp Combining Voice and Face Content in the Primate Temporal Lobe Catherine Perrodin and Christopher I. Petkov Neural Network Dynamics and Audiovisual Integration Julian Keil and Daniel Senkowski Cross-Modal Learning in the Auditory System Patrick Bruns and Brigitte Roeder Multisensory Processing Differences in Individuals with Autism Spectrum Disorder Sarah H. Baum Miller, Mark T. Wallace Adrian K.C. Lee is Associate Professor in the Department of Speech & Hearing Sciences and the Institute for Learning and Brain Sciences at the University of Washington, Seattle Mark T. Wallace is the Louise B McGavock Endowed Chair and Professor in the Departments of Hearing and Speech Sciences, Psychiatry, Psychology and Director of the Vanderbilt Brain Institute at Vanderbilt University, Nashville Allison B. Coffin is Associate Professor in the Department of Integrative Physiology and Neuroscience at Washington State University, Vancouver, WA Arthur N. Popper is Professor Emeritus and research professor in the Department of Biology at the University of Maryland, College Park Richard R. Fay is Distinguished Research Professor of Psychology at Loyola University, Chicago

A revolutionary new understanding of the human brain and its changeable nature. The brain is a dynamic, electric, living forest. It is not rigidly fixed but instead constantly modifies its patterns - adjusting to remember, adapting to new conditions, building expertise. Your neural networks are not hardwired but livewired, reconfiguring their circuitry every moment of your life. Covering decades of research - from synaesthesia to dreaming to the creation of new senses - and groundbreaking discoveries from Eagleman's own laboratory, Livewired surfs the leading edge of science to explore the most advanced technology ever discovered.

The book explores two fundamental aspects of the human mind and their relation to one another. The first is the way that information is put to use in the mind. When we are doing a mental arithmetic problem, for example, how do we bring the relevant bits of information to mind and hold them there while carrying out the series of calculations? This is working memory, the subject of an enormous research literature in psychology, neuroscience, and a great many other disciplines. Characterizing the working memory process is now a major part of efforts to understand the human mind. How we characterize this process depends of course on how we characterize the human mind as a whole. In particular, is the mind made up of a number of distinct units, each carrying out a specialized function? There is considerable reason to say that it is, and this modular view of the mind has become prominent in a great deal of academic work, notably in cognitive neuroscience, with important implications for our understanding of how working memory works. But these implications have received surprisingly little consideration to this point. The aim of the book is to explore this relation between working memory and modularity, first in general terms and then using a specific modular view of the mind - the Modular Cognition Framework. The ideas are illustrated and further developed through an application to language and especially second language acquisition and use.

Nutrition and Sensation, Second Edition continues to explore how sensations unravel the hidden sensory universe which acts to control our appetite and nutritional desires. The sensory influence on food is found everywhere-whether it is the color of soda, the viscosity of maple syrup, or the aroma of chocolate-the sensory experience fuels consumption. This book continues to discuss the impact of olfaction, gustation, retronasal olfaction, vision, vestibular function, hearing, and somatosensory and tactile nature on nutrition. It also focuses on the use of the sensory system to treat nutritional disorders including obesity, with attention to the mechanisms encompassing smell and taste and how this can influence satiety and weight. Nutrition and Sensation, Second Edition provides a deeper understanding of the fascinating link between the sensory system and nutrition.

The growth of the field of eating disorder research has led to a vast array of empirical articles, and the development of new animal models that can be used to study these disorders continues to stimulate new research. Animal Models of Eating Disorders serves as a collection of detailed techniques contributed by experts in the field who are well-versed in the development and implementation of these models. Since eating disorders are complex and likely due to a combination of environmental, genetic, and social causes, the detailed chapters of this volume have been designed to highlight different contributing factors. Collectively, these chapters give a comprehensive and representative overview of both recently developed and classic methodologies used in the study of eating disorders. Written for the popular Neuromethods series, this work contains the kind of thorough description and implementation advice that promises successful results. Authoritative and practical, Animal Models of Eating Disorders aims to aid researchers in the use of animal models to assist in their investigation and characterization of the behaviors and neurochemical alterations associated with these devastating disorders.

This volume explores the latest methods that seek to address the vital questions being asked in neurotoxicology research. The chapters in this book cover a variety of available methods from the molecular level to the organism level, and both in vitro and in vivo approaches, including alternative model organisms. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Experimental Neurotoxicology Methods is a valuable resource for both young and experienced researchers who are looking for guidance to implement these methods in their laboratories or for understanding the data generated through these techniques.

The book explores two fundamental aspects of the human mind and their relation to one another. The first is the way that information is put to use in the mind. When we are doing a mental arithmetic problem, for example, how do we bring the relevant bits of information to mind and hold them there while carrying out the series of calculations? This is working memory, the subject of an enormous research literature in psychology, neuroscience, and a great many other disciplines. Characterizing the working memory process is now a major part of efforts to understand the human mind. How we characterize this process depends of course on how we characterize the human mind as a whole. In particular, is the mind made up of a number of distinct units, each carrying out a specialized function? There is considerable reason to say that it is, and this modular view of the mind has become prominent in a great deal of academic work, notably in cognitive neuroscience, with important implications for our understanding of how working memory works. But these implications have received surprisingly little consideration to this point. The aim of the book is to explore this relation between working memory and modularity, first in general terms and then using a specific modular view of the mind - the Modular Cognition Framework. The ideas are illustrated and further developed through an application to language and especially second language acquisition and use.

* Suitable for researchers in mathematical neuroscience and potentially as supplementary reading for postgraduate students * Thoroughly researched and replete with references.

Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery methods for transgenes, will learn the characteristics of transgene delivery vectors, and come to understand the therapy for both neuro-oncologic and neurologic disorders.

The surge of philosophical interest in episodic memory has brought to light a number of controversial questions about this form of memory that have only recently begun to be addressed in detail. This book organises discussion around six such questions, offering two new chapters per question, from experts in the field. The questions are: I. What is the relationship between memory and imagination? II. Do memory traces have content? III. What is the nature of mnemonic confabulation? IV. What is the function of episodic memory? V. Do non-human animals have episodic memory? VI. Does episodic memory give us knowledge of the past? The book constitutes a valuable resource for researchers, teachers, and students alike. For researchers, it provides an up-to-date discussion of some of the main theories, arguments, and problems in the area. For teachers, the book can supply the readings for an entire course, or particular sections can provide the readings for specific units within a broader philosophy of memory course. For students, the book offers accessible discussions of some of the most recent topics in the philosophy of memory, which, when taken together, serve as a well-rounded introduction to the area.

Common sense philosophy holds that widely and deeply held beliefs are justified in the absence of defeaters. While this tradition has always had its philosophical detractors who have defended various forms of skepticism or have sought to develop rival epistemological views, recent advances in several scientific disciplines claim to have debunked the reliability of the faculties that produce our common sense beliefs. At the same time, however, it seems reasonable that we cannot do without common sense beliefs entirely. Arguably, science and the scientific method are built on, and continue to depend on, common sense. This collection of essays debates the tenability of common sense in the face of recent challenges from the empirical sciences. It explores to what extent scientific considerations-rather than philosophical considerations-put pressure on common sense philosophy. The book is structured in a way that promotes dialogue between philosophers and scientists. Noah Lemos, one of the most influential contemporary advocates of the common sense tradition, begins with an overview of the nature and scope of common sense beliefs, and examines philosophical objections to common sense and its relationship to scientific beliefs. Then, the volume features essays by scientists and philosophers of science who discuss various proposed conflicts between commonsensical and scientific beliefs: the reality of space and time, about the nature of human beings, about free will and identity, about rationality, about morality, and about religious belief. Notable philosophers who embrace the common sense tradition respond to these essays to explore the connection between common sense philosophy and contemporary debates in evolutionary biology, neuroscience, physics, and psychology.

Experiential evidence shows that pain is associated with common meanings. These include a meaning of threat or danger, which is experienced as immediately distressing or unpleasant; cognitive meanings, which are focused on the long-term consequences of having chronic pain; and existential meanings such as hopelessness, which are more about the person with chronic pain than the pain itself. This interdisciplinary book - the second in the three-volume Meanings of Pain series edited by Dr Simon van Rysewyk - aims to better understand pain by describing experiences of pain and the meanings these experiences hold for the people living through them. The lived experiences of pain described here involve various types of chronic pain, including spinal pain, labour pain, rheumatic pain, diabetic peripheral neuropathic pain, fibromyalgia, complex regional pain syndrome, endometriosis-associated pain, and cancer-related pain. Two chapters provide narrative descriptions of pain, recounted and interpreted by people with pain. Language is important to understanding the meaning of pain since it is the primary tool human beings use to manipulate meaning. As discussed in the book, linguistic meaning may hold clues to understanding some pain-related experiences, including the stigmatisation of people with pain, the dynamics of patient-clinician communication, and other issues, such as relationships between pain, public policy and the law, and attempts to develop a taxonomy of pain that is meaningful for patients. Clinical implications are described in each chapter. This book is intended for people with pain, their family members or caregivers, clinicians, researchers, advocates, and policy makers.

Humans are storytelling animals. Stories are what make our societies possible. Countless books celebrate their virtues. But Jonathan Gottschall, an expert on the science of stories, argues that there is a dark side to storytelling we can no longer ignore. Storytelling, the very tradition that built human civilization, may be the thing that destroys it. In The Story Paradox, Gottschall explores how a broad consortium of psychologists, communications specialists, neuroscientists, and literary quants are using the scientific method to study how stories affect our brains. The results challenge the idea that storytelling is an obvious force for good in human life. Yes, storytelling can bind groups together, but it is also the main force dragging people apart. And it's the best method we've ever devised for manipulating each other by circumventing rational thought. Behind all civilization's greatest ills-environmental destruction, runaway demagogues, warfare-you will always find the same master factor: a mind-disordering story. Gottschall argues that societies succeed or fail depending on how they manage these tensions. And it has only become harder, as new technologies that amplify the effects of disinformation campaigns, conspiracy theories, and fake news make separating fact from fiction nearly impossible. With clarity and conviction, Gottschall reveals why our biggest asset has become our greatest threat, and what, if anything, can be done. It is a call to stop asking, "How we can change the world through stories?" and start asking, "How can we save the world from stories?"

This volume explores current viewpoints and knowledge gaps in the field of traumatic brain injury (TBI). The chapters in this book cover topics ranging from development of in vitro and animal TBI models, to diagnostic imaging and disease monitoring in patients. Designing pre-clinical and clinical trials is also discussed. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Practical and thorough, Pre-Clinical and Clinical Methods in Brain Trauma Research is a valuable resource for both scientists and clinical researchers interested in learning about important techniques and their applications in the field of TBI.

Human Choice in International Law is an exploration of human choice in international legal and political decision making. This book investigates the neurobiology of how people choose and the history of how personal choice has affected decisions about international peace and security. It charts important decision moments in international law about genocide, intervention into armed conflict and nuclear weapons at the central institutions of the international legal order. Professor Spain Bradley analyzes the role that particular individuals, serving as international judges or Security Council representatives, play in shaping decision outcomes and then applies insights from neuroscience to assert the importance of analyzing how cognitive processes such as empathy, emotion and bias can influence such decisionmakers. Drawing upon historical accounts and personal interviews, this book reveals the beauty and struggle of human influences that shape the creation and practice of international law.

The study of the brain and behavior is illuminated with the discovery of invariances. Experimental brain research uncovers constancies amidst variation, with respect to interventions and transformations prescribed by experimental paradigms. Place cells, mirror neurons, event related potentials and areas differentially active in fMRI, all illustrate the pervasive role of invariances in neural systems in relation to their function.

This book highlights an innovative approach for extracting terminological cores from subject domain-bounded collections of professional texts. The approach is based on exploiting the phenomenon of terminological saturation. The book presents the formal framework for the method of detecting and measuring terminological saturation as a successive approximation process. It further offers the suite of the algorithms that implement the method in the software and comprehensively evaluates all the aspects of the method and possible input configurations in the experiments on synthetic and real collections of texts in several subject domains. The book demonstrates the use of the developed method and software pipeline in industrial and academic use cases. It also outlines the potential benefits of the method for the adoption in industry.