Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

An ancient doctor who advocated the therapeutic benefits of wine and passive exercise was bound to be successful. However, Asclepiades of Bithynia did far more than reform much of traditional Hippocratic therapeutic practice; he devised an extraordinary physical theory which he used to explain all biological phenomena in uniformly simple terms. His work laid the theoretical basis for the anti-theoretical medical sect called Methodism. For his trouble he was despised by his intellectual progeny and, more importantly perhaps, by Galen. None of his work survives intact, but copious ancient testimonia relating to him allow us to reconstruct many details of the theory. His ideas offer us a fascinating glimpse of how Hellenistic philosophy and medicine interacted, and provide an introduction to one of the most intriguing doctrinal disputes in Greek science.

This is a collection of important lecture and original articles and commentaries by Martin Perl, discoverer of the tau lepton and the third generation of elementary particles, and this year's Nobel Prize winner. This book contains a fascinating and realistic picture of experimental science based on the high energy physics research work carried out by him. Using reprints of his articles with his commentaries, the author presents the various aspects of experimental research in science: the pleasures and risks of experimental work; the pain and frustration with experiments that are useless or fail; the dreaming about experiments that were not carried out; the constant search for innovation and creativity in the work; and the special joy of discovery. The articles and commentaries range from the early days of bubble chambers and spark chambers in the 1950's to the author's present research, experiments at an electron-positron collider and a search for free quarks. The book is for the general reader as well as the scientist.

In this fascinating volume, scientist and teacher James S. Perlman shows us that science is not a dry, mechanistic process but a dynamic interplay between human beings and their surroundings, embodying their attempts to understand, anticipate, and cope with natural events. The interactive nature of science requires the use of our minds, imaginations, and sense-extending apparatus, such as telescopes and microscopes. We are reminded that scientists do not merely observe; they form ideas and images which they then project back upon nature to explain what they see. And these ideas and images are themselves influenced by the limitations of the observer as well as by prevailing social, intellectual, and technological conditions. In Science without Limits, Dr. Perlman takes us on an extraordinary voyage through history as he demonstrates the ways in which science developed as a distinctly human and evolving enterprise from early man to the present. On our journey Perlman introduces us to the great figures of Western science and how their discoveries modified existing ways of viewing the world.

Science and literature have always been strange bedfellows. Like puzzle pieces, they fit because they're different. Some of the greatest works of world literature have been inspired by the marvels of the scientific world. Scientists have written works of the imagination. Even formal scientific writings have been known to employ rhetoric. There is a tendency to think of literature--and the humanities in general--as having little to do with science. Yet scholars have conducted fruitful studies of the history and philosophy of science. With the rise of technology, scholars have also applied scientific analysis to the study of literature and the creative process. The intersection of scientific and humanistic inquiry is finally being mapped. This volume includes more than 650 A-Z entries on topics and themes in science and literature, significant writers, key scientists, seminal works, and important theories and methodologies.

This reference defines the rapidly emerging interdisciplinary field of literature and science. An introductory essay traces the history of the field, its growing reputation, and the current state of research. Broad in scope, the volume covers world literature from its beginnings to the present day and illuminates the role of science in literature and literary studies. A wide range of experts contributed entries to this volume, each of which concludes with a brief bibliography. The entire volume closes with a list of works for further reading.

Current environmental problems and technological risks are a challenge for a new institutional arrangement of the value spheres of Science, Politics and Morality. Distinguished authors from different European countries and America provide a cross-disciplinary perspective on the problems of political decision making under the conditions of scientific uncertainty. cases from biotechnology and the environmental sciences are discussed. The papers collected for this volume address the following themes: (i) controversies about risks and political decision making; (ii) concepts of science for policy; (iii) the use of social science in the policy making process; (iv) ethical problems with developments in science and technology; (v) public and state interests in the development and control of technology.

Naturalism and Pragmatism offers reflections on the pragmatic tradition from a fresh perspective: that of a working neuroscientist. Though naturalism and evolution are not the only topics of discussions, they are important themes of the book. Both pragmatism and modern behavioral science grew up in the wake of Darwin's theory of evolution. Indeed it is impossible to imagine either without evolutionary theory and the more general nineteenth-century trend of naturalism from which modern evolutionary theory emerged. And yet, for a variety of reasons, these common origins have not ensured a close affinity between pragmatic philosophy and the behavioral sciences. Among the wide diversity of scientific theories of human cognition and its evolutionary origins, only a few are congenial to pragmatism in its original or classical' form, which embraces the full range of human experience

British physicist John Tyndall dedicated much of his career to establishing the scientist as a cultural authority. His campaign to free science from the restraints of theology caused a national uproar, and in his popular books and lectures he promoted scientific education for all classes. Though he was often labeled a materialist, religion played a large role in Tyndall's vision of science, which drew on Carlyle and Emerson as well as his mentor Michael Faraday. Tyndall's ideas influenced the development of modern science, and in his efforts to create an authoritative role for scientists in society, he played a pivotal role in Victorian history.

Constructive empiricism is not just a view regarding the aim of science; it is also a view regarding the epistemological framework in which one should debate the aim of science. This is the focus of this book -- not with scientific truth, but with how one should argue about scientific truth.

Cassirer's thought-provoking essay Form and Technology (1930) considers the theoretical work performed by material instruments and, in so doing, it ascribes to technology a new dignity as a genuine tool of the mind in equal company with language and art. Germinating in this essay, we find an ambitious program for a new kind of philosophy of technology that resonates with contemporary approaches focusing on material apparatuses, relational and performative processes, and the embodied, embedded, and enacted nature of perception and cognition. Cassirer's approach, however, is unique in the way that it integrates logical concerns, championed by scientifically oriented philosophers, with the concerns of the historical and cultural sciences. The current revival of interest in Cassirer's thinking has precisely to do with its potential for bridging unproductive intellectual gaps. Form and Technology, especially, provides a rich resource for current attempts, across disciplines, to develop new conceptual and ontological frameworks. Cassirer's classic essay, translated here into English for the first time, is accompanied by ten critical essays that explore its current relevance.

Vitalism is understood as impacting the history of the life sciences, medicine and philosophy, representing an epistemological challenge to the dominance of mechanism over the last 200 years, and partly revived with organicism in early theoretical biology. The contributions in this volume portray the history of vitalism from the end of the Enlightenment to the modern day, suggesting some reassessment of what it means both historically and conceptually. As such it includes a wide range of material, employing both historical and philosophical methodologies, and it is divided fairly evenly between 19th and 20th century historical treatments and more contemporary analysis. This volume presents a significant contribution to the current literature in the history and philosophy of science and the history of medicine.

This book reconstructs key aspects of the early career of Descartes from 1618 to 1633; that is, up through the point of his composing his first system of natural philosophy, "Le Monde, " in 1629-33. It focuses upon the overlapping and intertwined development of Descartes projects in physico-mathematics, analytical mathematics, universal method, and, finally, systematic corpuscular-mechanical natural philosophy. The concern is not simply with the conceptual and technical aspects of these projects; but, with Descartes agendas within them and his construction and presentation of his intellectual identity in relation to them.

Descartes technical projects, agendas and senses of identity shifted over time, entangled and displayed great successes and deep failures, as he morphed from a mathematically competent, Jesuit trained graduate in neo-Scholastic Aristotelianism to aspiring prophet of a systematised corpuscular-mechanism, passing through stages of being a committed "physico-mathematicus," advocate of a putative universal mathematics, and projector of a grand methodological dream. In all three dimensions projects, agendas and identity concerns the young Descartes struggled and contended, with himself and with real or virtual peers and competitors, hence the title "Descartes-Agonistes" .

"

Human consciousness has perplexed philosophers, artists and scientists for centuries. Some hold it to be purely physical, while others believe it transcends the material world. Now comes a book that offers a new perspective - based entirely on evidence from the natural sciences - whereby materialism and dualism co-exist. The author - a distinguished pioneer of nonlinear dynamics - bases his argument on a hierarchical view of mental organization; a stairway. Atoms give rise to molecules, neurons form the brain and individual consciousness leads to shared culture. All steps are needed to complete the picture and each level derives from the previous one. The book shows specialists how each of their fields adds to the overall picture, while providing general readers with an introduction to this investigation.

Reviews of Not Saussure and The Explicit Animal: Not Saussure - 'I greatly enjoyed it...' - Bernard Bergonzi 'The Explicit Animal - '...his books are genuine contributions to professional debate...' - Stephen R.L. Clarke, Times Literary Supplement;Newton's Sleep examines the complementary roles of science and art in human life. Science has been criticised for being at best useful but spiritually derelict, and art for attempting to answer the spiritual needs of humankind while ignoring the material needs of millions who live in want. Newton's Sleep deals with the charges that science is spiritually empty and that art fails in its civilising mission by relating these aspects of human culture to the physical and metaphysical hungers of an explicit animal who lives in both the Kingdom of Means and the Kingdom of Ends. 'Tallis can, and frequently does, write extremely well. He also writes with considerable passion...Tallis...is perhaps best seen as an exceptionally interesting and broad-minded heir to Huxley, preaching the cause of the Church Scientific...' Richard Webster

This ninth volume is one of the most arnbitious in the Philosophy and Technology series. Edited by technopolitical philosopher Langdon Winner, it assembles an impressive collection of philosophers and political theorists to discuss one of the most important topics of the end of the twentieth century - the bearing of technology, in all its rarnifica tions, on the practice of democratic politics in the developed world. When set beside the previous volume in the series - Europe, America, and Teehnology - the two together open a philosophical dialogue of great significance about the ways technology challenges democracy at its very roots. Some philosophers think the attack is fatal. Others are optimistic that democratic means can be discovered, or invented, for the control of technology. Still others object to an optimism-versus-pes simism formulation of the issue. But alI agree that the issue is highly significant, one that demands serious philosophical inquiry. The Society for Philosophy and Technology was fortunate in being able to draw this group of writers to Bordeaux, France, in 1989, along with a large number of others whose contributions to the debate could not be included here. It is equally fortunate to have chosen Langdon Winner as president when the time carne to select the best of the papers to fashion this volume. University of Delaware PAUL T."

In Embodied Minds in Action, Robert Hanna and Michelle Maiese work out a unified treatment of three fundamental philosophical problems: the mind-body problem, the problem of mental causation, and the problem of action. This unified treatment rests on two basic claims. The first is that conscious, intentional minds like ours are essentially embodied. This entails that our minds are necessarily spread throughout our living, organismic bodies and belong to their complete neurobiological constitution. So minds like ours are necessarily alive. The second claim is that essentially embodied minds are self-organizing thermodynamic systems. This entails that our mental lives consist in the possibility and actuality of moving our own living organismic bodies through space and time, by means of our conscious desires. The upshot is that we are essentially minded animals who help to create the natural world through our own agency. This doctrine--the Essential Embodiment Theory--is a truly radical idea which subverts the traditionally opposed and seemingly exhaustive categories of Dualism and Materialism, and offers a new paradigm for contemporary mainstream research in the philosophy of mind and cognitive neuroscience.

What are individuals? How can they be identified? These are crucial questions for philosophers and scientists alike. Criteria of individuality seem to differ markedly between metaphysics and the empirical sciences - and this might well explain why no work has hitherto attempted to relate the contributions of metaphysics, physics and biology on this question. This timely volume brings together various strands of research into 'individuality', examining how different sciences handle the issue, and reflecting on how this scientific work relates to metaphysical concerns. The collection makes a major contribution to clarifying and overcoming obstacles to the construction of a general conception of the individual adequate for both physics and biology, and perhaps even beyond.

Wittgenstein criticised prevailing attitudes toward the sciences. The target of his criticisms was 'scientism': what he described as 'the overestimation of science'. This collection is the first study of Wittgenstein's anti-scientism - a theme in his work that is clearly central to his thought yet strikingly neglected by the existing literature. The book explores the philosophical basis of Wittgenstein's anti-scientism; how this anti-scientism helps us understand Wittgenstein's philosophical aims; and how this underlies his later conception of philosophy and the kind of philosophy he attacked. An outstanding team of international contributors articulate and critically assess Wittgenstein's views on scientism and anti-scientism, making Wittgenstein and Scientism essential reading for students and scholars of Wittgenstein's work, on topics as varied as the philosophy of mind and psychology, philosophical practice, the nature of religious belief, and the place of science in modern culture. Contributors: Jonathan Beale, William Child, Annalisa Coliva, David E. Cooper, Ian James Kidd, James C. Klagge, Daniele Moyal-Sharrock, Rupert Read, Genia Schoenbaumsfeld, Severin Schroeder, Benedict Smith, and Chon Tejedor.

Are science and technology independent of one another? Is technology dependent upon science, and if so, how is it dependent? Is science dependent upon technology, and if so how is it dependent? Or, are science and technology becoming so interdependent that the line dividing them has become totally erased? This book charts the history of technoscience from the late nineteenth century to the end of the twentieth century and shows how the military-industrial-academic complex and big science combined to create new examples of technoscience in such areas as the nuclear arms race, the space race, the digital age, and the new worlds of nanotechnology and biotechnology.

The splendid achievements of Japanese mathematics and natural sciences during the second half of our 20th century have been a revival, a Renaissance, of the practical sciences developed along with the turn toward Western thinking in the late 19th century. The equally admirable results of Japanese philosophers (and historians) of science in our time followed upon a period less congenial to Western interests in the philosophical questions linked to modern science; and this reluctance to confront the epistemology, not even the humane significance, of the sciences went along with devotion to other Western trends. Thus, with the 'new' Japan of the Meiji restoration of 1868, and the early introduction of Western philosophy in the subsequent decade by Nishi Amane, a period of intellectual attraction to utilitarian, positivist, evolutionary, even materialist outlooks was soon replaced by devotion to scholarly work on Kant and Hegel, on ethical and general philosophical idealism. These studies often could emulate the critical spirit (the philosopher Onishe Hajime, praised for his own critical independence, was known as the Japanese Kant) but the neo Kantian and neo-Hegelian developments were not much affected by either empirical sciences or theoretical speculations about Nature. The pre-eminent philosopher of Japan ofthe first half of our century was Nishida Kitaro, with a pioneering treatise A Study of the Good, who, with his leading student Tanabe Hajime, formed the 'Kyoto School' of pre-war philosophy."

This book gives a state-of-the-art survey of current research in logic and philosophy of science, as viewed by invited speakers selected by the most prestigious international organization in the field. In particular, it gives a coherent picture of foundational research into the various sciences, both natural and social. In addition, it has special interest items such as symposia on interfaces between logic and methodology, semantics and semiotics, as well as updates on the current state of the field in Eastern Europe and the Far East.

to the Moral Challenges H. Tristram Engelhardt, Jr. and Aaron E. Hinkley 1 Taking Finitude Seriously in a Chinese Cultural Context Across the world, health care policy is a moral and political challenge. Few want to die young or to suffer, yet not all the money in the world can deliver physical immortality or a life free of suffering. In addition, health care needs differ. As a result, unless a state coercively forbids those with the desire and means to buy better basic health care to do so, access to medicine will be unequal. No co- try can afford to provide all with the best of care. In countries such as China, there are in addition stark regional differences in the quality and availability of health care, posing additional challenges to public policy-making. Further, in China as elsewhere, the desire to lower morbidity and mortality risks has led to ever more resources being invested in health care. When such investment is supported primarily by funds derived from taxation, an increasing burden is placed on a country's economy. This is particularly the case as in China with its one-child policy, where the proportion of the elderly population consuming health care is rising. Thesepolicychallengesarecompoundedbymoraldiversity. Defacto, humansdo not share one morality. Instead, they rank cardinal human goods and right-making conditions in different orders, often not sharing an af?rmation of the same goods or views of the right.

The author attempts to show that scientific realism is compatible with the presence of idealization in the sciences. His main contention is that idealized theories can be treated as counterfactuals about how things are in worlds that are similar to but simpler than the actual world.

In three volumes, a distinguished group of scholars from a variety of disciplines in the natural and social sciences, the humanities and the arts contribute essays in honor of Robert S. Cohen, on the occasion of his 70th birthday. The range of the essays, as well as their originality, and their critical and historical depth, pay tribute to the extraordinary scope of Professor Cohen's intellectual interests, as a scientist-philosopher and a humanist, and also to his engagement in the world of social and political practice. The essays presented in Physics, Philosophy, and the Scientific Community (Volume I of Essays in Honor of Robert S. Cohen) focus on philosophical and historical issues in contemporary physics: on the origins and conceptual foundations of quantum mechanics, on the reception and understanding of Bohr's and Einstein's work, on the emergence of quantum electrodynamics, and on some of the sharp philosophical and scientific issues that arise in current scientific practice (e.g. in superconductivity research). In addition, several essays deal with critical issues within the philosophy of science, both historical and contemporary: e.g. with Cartesian notions of mechanism in the philosophy of biology; with the language and logic of science - e.g. with new insights concerning the issue of a physicalistic' language in the arguments of Neurath, Carnap and Wittgenstein; with the notion of elementary logic'; and with rational and non-rational elements in the history of science. Two original contributions to the history of mathematics and some studies in the comparative sociology of science round off this outstanding collection.