This book presents a comprehensive description of phonons and their interactions in systems with different dimensions and length scales. Internationally-recognized leaders describe theories and measurements of phonon interactions in relation to the design of materials with exotic properties such as metamaterials, nano-mechanical systems, next-generation electronic, photonic, and acoustic devices, energy harvesting, optical information storage, and applications of phonon lasers in a variety of fields.

The emergence of techniques for control of semiconductor properties and geometry has enabled engineers to design structures in which functionality is derived from controlling electron behavior. As manufacturing techniques have greatly expanded the list of available materials and the range of attainable length scales, similar opportunities now exist for designing devices whose functionality is derived from controlling phonon behavior. However, progress in this area is hampered by gaps in our knowledge of phonon transport across and along arbitrary interfaces, the scattering of phonons with crystal defects, interface roughness and mass-mixing, delocalized electrons/collective electronic excitations, and solid acoustic vibrations when these occur in structures with small physical dimensions. This book providesa comprehensive description of phonons and their interactions in systems with different dimensions and length scales. Theories and measurements of phonon interactions are described in relation to the design of materials with exotic properties such as metamaterials, nano-mechanical systems, next-generation electronic, photonic, and acoustic devices, energy harvesting, optical information storage, and applications of phonon lasers in a variety of fields."

The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.

This thesis unites the fields of optical atomic clocks and ultracold molecular science, laying the foundation for optical molecular measurements of unprecedented precision. Building upon optical manipulation techniques developed by the atomic clock community, this work delves into attaining surgical control of molecular quantum states. The thesis develops two experimental observables that one can measure with optical-lattice-trapped ultracold molecules: extremely narrow optical spectra, and angular distributions of photofragments that are ejected when the diatomic molecules are dissociated by laser light pulses. The former allows molecular spectroscopy approaching the level of atomic clocks, leading into molecular metrology and tests of fundamental physics. The latter opens the field of ultracold chemistry through observation of quantum effects such as matter-wave interference of photofragments and tunneling through reaction barriers. The thesis also describes a discovery of a new method of thermometry that can be used near absolute zero temperatures for particles lacking cycling transitions, solving a long-standing experimental problem in atomic and molecular physics.

This book covers the main ideas, methods, recent developments and applications of quantum-limit optical spectroscopy to quantum information, resolution spectroscopy, measurements beyond quantum limits, measurement of decoherence and entanglement. Quantum-limit spectroscopy lies at the frontier of current experimental and theoretical techniques, and is one of the areas of atomic spectroscopy where the quantization of the field is essential to predict and interpret the existing experimental results. Currently, there is an increasing interest in quantum and precision spectroscopy both theoretically and experimentally, due to a significant progress in trapping and cooling of single atoms and ions. This progress allows to explore in the most intimate detail the ways in which light interacts with atoms and to measure spectral properties and quantum effects with a large precision. Moreover, it allows to perform subtle tests of quantum mechanics on the single atom and single photon scale which were hardly even imaginable as ``thought experiments'' a few years ago.

A collection of infrared and Raman spectra of 500 natural and synthetic polymers of industrial importance is presented in this book. A large variety of compounds are included, starting with linear polyolefins and finishing with complex biopolymers and related compounds. The spectra were registered using Infrared Fourier Transform Spectrometers in the laboratory of the All-Russia Institute of Forensic Sciences. The IR and Raman spectra are presented together on the same sheet. The accompanying data include general and structure formulae, CAS register numbers, and sample preparation conditions.

Features of this book:

Continues the long tradition of publishing specific and standard data of new chemical compounds.

For low-molecular weight substances, complementary IR and Raman spectra are featured on the same sample and printed on the same page. This "fingerprint" data allows the substance of the sample to be identified without doubt.

An important feature of this unique collection of data is the increase in the identification precision of unknown substances.

Peak tables are available in digital (ASCII) format, on a diskette delivered with the book. This allows the user to search for unknowns.

All the spectra in the collection are base-line corrected.

This book will be of interest to scientists involved in the synthesis of new polymeric materials, polymer identification, and quality control. Libraries of scientific institutes, research centers, and universities involved in vibrational spectroscopy will also find this collection invaluable."

Tingyue Gu's second edition provides a comprehensive set of nonlinear multicomponent liquid chromatography (LC) models for various forms of LC, such as adsorption, size exclusion, ion-exchange, reversed-phase, affinity, isocratic/gradient elution and axial/radial flow LC. Much has advanced since the first edition of this book and the author's software, described here, is now used for teaching and research in 32 different countries. This book comes together with a complete software package with graphical user interface for personal computers, offered free for academic applications. Additionally, this book provides detailed methods for parameter estimation of mass transfer coefficients, bed voidage, particle porosity and isotherms. The author gives examples of how to use the software for predicitons and scale-up. In contrast to the first edition, authors do not need to deal with complicated math. Instead, they focus on how to obtain a few parameters for simulation and how to compare simulation results with experimental data. After reading the detailed descriptions in the book, a reader is able to use the simulation software to investigate chromatographic behavior without doing actual experiments. This book is aimed at readers who are interested in learning about LC behaviors and at those who want to scale up LC for preparative- and large-scale applications. Both academic personnel and industrial practitioners can benefit from the use of the book. This new edition includes: - New models and software for pellicular (cored) beads in liquid chromatography - Introduction of user-friendly software (with graphical user interface) - Detailed descriptions on how to use the software - Step-by-step instructions on parameter estimation for the models - New mass-transfer correlations for parameter estimation - Experimental methods for parameter estimation - Several actual examples using the model for product development and scale-up - Updated literature review

This book explores the conversion for solar energy into renewable liquid fuels through electrochemical reactions. The first section of the book is devoted to the theoretical fundamentals of solar fuels production, focusing on the surface properties of semiconductor materials in contact with aqueous solutions and the reaction mechanisms. The second section describes a collection of current, relevant characterization techniques, which provide essential information of the band structure of the semiconductors and carrier dynamics at the interface semiconductor. The third, and last section comprises the most recent developments in materials and engineered structures to optimize the performance of solar-to-fuel conversion devices.

This volume is a collection of lectures presented during the 2009 International School on High-pressure Crystal- graphy, which took place at the Ettore Majorana Center for Scientific Culture, between June 4 and 14, 2009, in the very picturesque Sicilian town of Erice. st The 2009 school was the 41 course of the "International School of Cryst- lography" organized at the Majorana Center and was directed by Elena Figure 1. Audience, including local Boldyreva (Novosibirsk University) organizers (orange scarfs) and student and Przemyslaw Dera (University of participants during one of the lectures. Chicago). Unmatched support and excellent on-site organization was provided by the expert team consisting of Prof. Paola Spadon (Uniersity of Padova), Prof. Lodovico Riva di San Severino (University of Bologna), Elena Papinutto and Prof. John Irvin (University of California, San Franciso), aided by great team of young local organizers ("orange scarfs"). Major part of funding for the school was provided by a grant from the NATO Science for Peace and Security program, through which the 2009 Erice school was recognized as a NATO Advanced Study Institute (ASI).

As mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step procedures for the analysis of number of analytes of clinical importance. This versatile and expansive volume covers mass spectrometry methods for analytes including a variety of drugs, hormones, and metabolic compounds spanning the disciplines of toxicology, therapeutic drug monitoring, endocrinology, and pediatric metabolism. Written in the highly successful Methods in Molecular BiologyT series format, chapters include brief introductions to the analytes, lists of the necessary materials and reagents, readily reproducible analytical protocols, and detailed notes on troubleshooting and avoiding known pitfalls. Comprehensive and dependable, Clinical Applications of Mass Spectrometry: Methods and Protocols offers its readers a wide array of valuable methods for experienced mass spectrometric labs that are looking to introduce new analyses as well as for those laboratories currently considering the addition of this resourceful and vital technology. Written for: Biochemists, laboratory scientists, pharmacologists, toxicologists, and endocrinologists

Reflecting the expanding field's need for reliable protocols, Fluorescence Spectroscopy and Microscopy: Methods and Protocols offers techniques from a worldwide team of experts on this versatile and vital subject. The topics covered fall into four broad categories: steady-state fluorescence spectroscopy, time-resolved fluorescence spectroscopy, fluorescent probe development, and the various sub-categories of fluorescence microscopy, such as fluorescence recovery after photobleaching (FRAP), live cell FRET imaging (FRETim), fluorescence lifetime imaging (FLIM), fluorescence fluctuation spectroscopy (FFS), and single-molecule fluorescence spectroscopy (smFS). Written as a part of the popular Methods in Molecular Biology series, chapters include the kind of unambiguous detail and key implementation advice that proves essential for successful results. Comprehensive and practical, Fluorescence Spectroscopy and Microscopy: Methods and Protocols aims to guide both 'novice' and established scientists toward furthering their research with these invaluable techniques.

This book draws on the latest research to discuss the history and development of high-entropy alloys and ceramics in bulk, film, and fiber form. High-entropy materials have recently been developed using the entropy of mixing and entropy of configuration of materials, and have proven to exhibit unique properties superior to those of conventional materials. The field of high-entropy alloys was born in 2004, and has since been developed for both scientific and engineering applications. Although there is extensive literature, this field is rapidly transforming. This book highlights the cutting edge of high-entropy materials, including their fundamentals and applications. Above all, it reflects two major milestones in their development: the equi-atomic ratio single-phase high-entropy alloys; and the non-equi-atomic ratio dual-phase high-entropy alloys.

This book presents the latest advances in ultrafast science, including both ultrafast optical technology and the study of ultrafast phenomena. It covers picosecond, femtosecond, and attosecond processes relevant to applications in physics, chemistry, biology, and engineering. Ultrafast technology has a profound impact in a wide range of applications, amongst them biomedical imaging, chemical dynamics, frequency standards, material processing, and ultrahigh-speed communications. This book summarizes the results presented at the 19th International Conference on Ultrafast Phenomena and provides an up-to-date view of this important and rapidly advancing field.

This book gives a detailed account of the holistic research carried out on the analytical data obtained historically on the products of the Nantgarw and Swansea porcelain manufactories which existed for a few years only during the second decade of the 19th Century. A background to the establishment of the two factories, which are linked through the persons of the enigmatic William Billingsley and his kiln manager, Samuel Walker, involves the sourcing of their raw materials and problems associated with the manufacture and distribution of the finished products. A description of the minerals and additives used in porcelain production is recounted to set the scene for the critical evaluation of the comprehensive analytical data which have been published on Nantgarw and Swansea porcelains. For the first time, the author has adopted a nondestructive technique, Raman spectroscopy, to interrogate perfect samples of Nantgarw and Swansea porcelain, as well as a selection of shards from an archaeological excavation carried out at a waste dump at the Nantgarw China Works site. Following these experiments, several questions relating to the porcelain bodies of Swansea and Nantgarw china can be answered and a protocol established for the preliminary evaluation of items of suspect attribution to confirm or not the correctness of their assignment to these Welsh porcelain factories.

Sean Ashton's doctoral thesis, which he finished at the Technical University in Munich, describes the challenge of constructing a Differential Electrochemical Mass Spectrometer instrument (DEMS). DEMS combines an electrochemical cell with mass spectrometry via a membrane interface, allowing gaseous and volatile electrochemical reaction species to be monitored online. The thesis carefully introduces the fuel cell electrocatalyst development concerns before reviewing the pertinent literature on DEMS. This is followed by the presentation and discussion of the new extended design, including a thorough characterization of the instrument. The capabilities of the new setup are demonstrated in two research studies: The methanol oxidation reaction on Pt and PtRu catalysts, and the electrochemical corrosion of fuel cell catalyst supports. Despite both topics having long since been studied, new insights can be obtained through careful investigations with the new DEMS instrument that are of great, general interest. The thesis and the instrument thus show the way for future investigations in the field.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 260 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.
Key Features
* Liquid chromatography
* Electrophoresis
* Mass spectrometry

Nuclear Magnetic Resonance Probes of Molecular Dynamics describes the theoretical basis and experimental techniques that make modern NMR spectroscopy a powerful and flexible tool for probing molecular dynamics in chemical, physical, and biochemical systems. Individual chapters, written by leaders in the development and application of NMR from around the world, treat systems that range from synthetic polymers, liquid crystals, and catalysts to proteins and oligonucleotides and techniques that include deuterium NMR, magic angle spinning, multidimensional spectroscopy, and magnetic resonance imaging. A combination of elementary and advanced material makes the book a useful introduction to the field for students at the graduate level as well as an important reference for practising NMR spectroscopists.

The modern vision of the micromechanism of friction and wear is explored, from the examination of ideal and real crystal structure and adhesion properties to the dynamics of solid frictional interaction. The fundamental quantum-mechanical and relativity principles of particle interaction are considered as basis of friction micro-process examination. The changes in solid structure originated from the influence of different kinds of force fields are considered. The principal possibility of relativity effect manifestation by friction is explained. The critical state of friction - triboplasma - was studied. Structural peculiarities of triboplasma, the kinetics of its transformation during frictional interaction as well as the influence of plasma and postplasma processes on tribojunction friction characteristics and complex formation by friction were examined. The book addresses to tribology researchers.

Photobiology integrates a wide variety of scientific disciplines. As more people become aware of the many ways light interacts with chemical and biological systems, the need for a concise treatment of photobiology has become more critical. Kohen "et al." Have written just such a book, intended both as a textbook and as a reference.
The authors begin by providing a brief description of the nature of light, how it affects matter, and the means and methods of measuring it. A major section of the book is devoted to how light influences living systems, including discussions of photosynthesis, bioluminescence, regulatory mechanisms, and visual transduction of light. The last half of the book is devoted to the biomedical aspects of light, including photoimmunology, photoallergic reactions and other forms of light sensitivity, the optical properties of skin, and various ways that light can be used in therapy treatments.
Useful to photobiologists as a comprehensive overview, this book should also appeal to biomedical researchers and advanced students of photobiology.

"Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC): Methods and ""Protocols "provides a synopsis of a large array of different SILAC methods by presenting a set of protocols that have been established by renowned scientists and their working groups. These include methods and protocols for the labeling of various model organisms as well as advanced strategies relying on SILAC, e.g. for the analysis of protein interactions, the mapping of posttranslational modifications or the characterization of subcellular proteomes. Written in the highly successful "Methods in Molecular Biology "series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, "Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC): ""Methods and Protocols "will serve students and experienced scientists alike as a valuable reference of how to make use of the SILAC technology for their own research.

This book highlights the various topics in which luminescence and electrochemistry are intimately coupled. The topic of this book is clearly at the frontier between several scientific domains involving physics, chemistry and biology. Applications in these various fields naturally also need to be mentioned, especially concerning displays and advanced investigation techniques in analytical chemistry or for biomedical issues.

This book describes the design, construction, and characterization of a new type of aberration-corrected, neutral-atom lens. Atom beam control plays a crucial role in many different fields, ranging from fundamental physics research and materials science to applied nanotechnology. Despite this, atom-optical elements like lenses and mirrors remain relatively underdeveloped compared to their counterparts in other optics fields. Although aberration correction is addressed quite comprehensively in photon and electron lenses, no credible research efforts have yet produced the same technology for neutral atoms. It reports on progress towards a neutral atom imaging device that will be useful in a range of applications, including nanofabrication and surface microscopy. It presents a novel technique for improving refractive power and correcting chromatic aberration in atom lenses based on a fundamental paradigm shift from continuous, two-dimensional focusing to a pulsed, three-dimensional approach. Simulations of this system suggest that it will pave the way towards the long-sought goal of true atom imaging on the nanoscale. The book further describes the construction of a prototype lens, and shows that all of the technological requirements for the proposed system are easily satisfied. Using metastable neon from a supersonic source, the prototype was characterized for three different focal lengths and a diverse range of apertures. Despite some manufacturing imperfections, lower distortion and higher resolution than has been shown in any previous hexapole lens was observed. Comparison with simulations corroborates the underlying theory and encourages further refinement of the process.

A thorough assessment of the applications of inorganic mass spectrometry

Mass spectrometry is a powerful analytical technique used to identify unknown compounds, to quantify known materials, and to elucidate the structural and chemical properties of molecules. Inorganic mass spectrometry focuses on the analysis of metals and elements rather than organic compounds. Applications of Inorganic Mass Spectrometry describes developments in mass spectrometric instrumentation, together with applications in metrology, nuclear science, cosmochemistry, geoscience, environmental science, and planetary science.

Divided into two parts, the first part of the book reviews the numerous technological advances that have occurred in mass spectrometry since 1947, a date regarded as the birth of modern mass spectrometry. The second part offers an up-to-date description of the many applications of inorganic mass spectrometry and includes a comprehensive set of references for each application.

It is doubtful that any other analytical instrument has had such a significant impact in so many fields of science as mass spectrometry. Applications of Inorganic Mass Spectrometry provides researchers, scientists, and engineers with an essential reference for this vital science.