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Books > Medicine > Pre-clinical medicine: basic sciences > General

Fundamentals of Anatomy & Physiology, Global Edition + Mastering a&P with Pearson Etext (Mixed media product, 11 Ed): Edwin... Fundamentals of Anatomy & Physiology, Global Edition + Mastering a&P with Pearson Etext (Mixed media product, 11 Ed)
Edwin Bartholomew
R2,643 Discovery Miles 26 430 Ships in 12 - 17 working days

For courses in two-semester A&P. This package includes Pearson Mastering (TM) Anatomy & Physiology Using Art Effectively to Teach the Toughest Topics in A&P Fundamentals of Anatomy & Physiology helps students succeed in the challenging A&P course with an easy-to-understand narrative, precise visuals, and steadfast accuracy. With the 11th Edition, the author team draws from recent research exploring how students use and digest visual information to help students use art more effectively to learn A&P. New book features encourage students to view and consider figures in the textbook, and new narrated videos guide students through complex physiology figures to help them deconstruct and better understand complicated processes. Instructors can also request a new handbook by Lori Garrett, entitled The Art of Teaching A&P: Six Easy Lessons to Improve Student Learning, which explores some of the most common challenges encountered when using art to teach A&P, alongside strategies to address these challenges. This package includes Pearson Mastering (TM) Anatomy & Physiology, an online homework, tutorial, and assessment product designed to engage students and improve results by helping students stay on track in the course and quickly master challenging A&P concepts. Features in the text are supported by Pearson Mastering (TM) Anatomy & Physiology assignments, including new SmartArt Videos, Interactive Physiology 2.0, Dynamic Study Modules, Learning Catalytics, Spotlight Figure Coaching Activities, lab study tools, Get Ready for A&P, plus a variety of Art Labeling Questions, Clinical Application Questions, and more. Mastering should only be purchased when required by an instructor. Please be sure you have the correct ISBN and Course ID. Instructors, contact your Pearson rep for more information.

Serum/Plasma Proteomics - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2011): Richard J.... Serum/Plasma Proteomics - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2011)
Richard J. Simpson, David W. Greening
R4,285 Discovery Miles 42 850 Ships in 10 - 15 working days

Blood science has become a cornerstone of multiple disciplines, including clinical chemistry, disease diagnosis, and therapeutic monitoring. Over the past decade, we have witnessed the advent of increasingly powerful proteomics technologies that allow greater fundamental insights into the blood proteome. These technological improvements have, in part, fuelled the quest for the discovery of novel blood-based biomarkers of disease. Serum/Plasma Proteomics: Methods and Protocols is a comprehensive resource of protocols for areas, pre-analytical through to analytical, of plasma and serum proteomics. Divided into five convenient sections, this detailed volume covers fractionation strategies for in-depth blood proteome analysis, defined procedures for blood collection, handling and storage, detailed protocols for performing both antibody-based and non-antibody based quantitative assays, proteome analysis of blood cell compartments, circulating nanomebraneous vesicles and blood-related fluids, and finally data management, statistical design, and bioinformatic challenges. This book, contributed to by leading experts in the field, provides a valuable foundation for the development and application of blood-based proteomics. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Serum/Plasma Proteomics: Methods and Protocols, with its well-honed methodologies, seeks to serve both professionals and investigators new to the field in an effort to further our knowledge of this fundamental science.

Class 1 Oxidoreductases - EC 1 (Paperback, Softcover reprint of the original 2nd ed. 2009): Antje Chang Class 1 Oxidoreductases - EC 1 (Paperback, Softcover reprint of the original 2nd ed. 2009)
Antje Chang; Edited by Dietmar Schomburg, Ida Schomburg
R8,642 Discovery Miles 86 420 Ships in 10 - 15 working days

The Springer Handbook of Enzymes provides concise data on 4,457 enzymes - and here is the second, updated edition. The enzymes are sufficiently well characterized for application in analytical, synthetic and biotechnology processes as well as in food industry. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus synonym index.

Class 1 Oxidoreductases X - EC 1.9 - 1.13 (Paperback, Softcover reprint of the original 2nd ed. 2006): Antje Chang Class 1 Oxidoreductases X - EC 1.9 - 1.13 (Paperback, Softcover reprint of the original 2nd ed. 2006)
Antje Chang; Edited by Dietmar Schomburg, Ida Schomburg
R8,621 Discovery Miles 86 210 Ships in 10 - 15 working days

The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.

Structure & Function of the Body - Hardcover (Hardcover, 16th edition): Kevin T. Patton, Gary A. Thibodeau Structure & Function of the Body - Hardcover (Hardcover, 16th edition)
Kevin T. Patton, Gary A. Thibodeau
R1,893 Discovery Miles 18 930 Ships in 9 - 15 working days

Get a solid understanding of the human body! Using simple, conversational language and vivid animations and illustrations, Structure & Function of the Body, 16th Edition introduces the normal structure and function of the human body and what the body does to maintain homeostasis. To help make difficult A&P concepts easy to understand, this new edition features thoroughly revised content and review questions which reflect the most current information available and a unique 22-page, semi-transparent insert of the human body. Plus, Connect It! boxes throughout directly correlate to online content giving you additional clinical and scientific insights essential to patient care! 22-page Clear View of the Human Body is a unique, full-color, semi-transparent insert depicting the human body (male and female) in layers. Conversational and clear writing style makes content easy to read and understand. Full-color design contains more than 400 drawings and photos. Updated study tips sections at the beginning of each chapter help break down difficult topics and guide you on how to best use book features to their advantage. Questions for student review are found throughout the chapters and cover critical thinking, open-ended, fill-in-the-blank, matching, multiple-choice, and other question formats. Special boxes such as Health and Well-Being boxes, Clinical Application boxes, Research and Trends boxes, and more help you apply what you have learned to your future career. Language of Science and Medicine section in each chapter includes key terms, word parts, and pronunciations to place a greater focus on medical terminology. Resources on the Evolve companion website include Animation Direct, audio summaries, audio glossary, a new online coloring book, review questions, and FAQs. NEW! Thoroughly revised chapters, illustrations, and review questions reflect the most current information available. NEW! Connect It! boxes refer you to online content providing additional clinical and scientific insights. NEW! A&P contributors join Dr. Patton to enhance the content and bring additional perspectives to the book.

Membrane Receptors, Channels and Transporters in Pulmonary Circulation (Paperback, 2010 ed.): Jason X.-J. Yuan, Jeremy P. T.... Membrane Receptors, Channels and Transporters in Pulmonary Circulation (Paperback, 2010 ed.)
Jason X.-J. Yuan, Jeremy P. T. Ward
R6,527 Discovery Miles 65 270 Ships in 10 - 15 working days

Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of expression and function of receptors, channels and transporters and their interrelationships contribute to the pathogenesis of pulmonary vascular disease; and iii) the therapeutic opportunities that may be revealed by enhancing our understanding of this area. The overall goal was to explore the mechanisms by which specific receptors, channels and transporters contribute to pulmonary vascular function in both health and disease, and how this knowledge may lead to novel interventions in lung dysplasia, pulmonary edema, lung injury, and pulmonary and systemic hypertension to reduce and prevent death from lung disease. Membrane Receptors, Channels and Transporters in Pulmonary Circulation is divided into six parts. Part 1 (Ion Channels in the Pulmonary Vasculature: Basics and New Findings) is designated for basic knowledge and recent findings in the research field of ion channels in pulmonary circulation. There are five chapters in Part I discussing the function, expression, distribution and regulation of various ion channels present in pulmonary vascular smooth muscle cells and how these channels are integrated to regulate intracellular Ca2+ and cell functions. Part II (TRP Channels in the Pulmonary Vasculature: Basics and New Findings) is composed of five chapters that are exclusively designed to discuss the role of a recently identified family of cation channels, transient receptor potential (TRP) channels, in the regulation of pulmonary vascular tone and arterial structure. Part III (Pathogenic Role of Ion Channels in Pulmonary Vascular Disease) includes four chapters that discuss how abnormal function and expression of various ion channels contribute to changes in cell functions and the development of pulmonary hypertension. Part IV (Receptors and Signaling Cascades in Pulmonary Arterial Hypertension) consists of five chapters devoted to the role of bone morphogenetic protein receptors, Notch receptors, serotonin receptors, Rho kinase and vascular endothelial growth factor receptors in the development of pulmonary arterial hypertension. Part V (Receptors and Transporters: Role in Cell Function and Hypoxic Pulmonary Vasoconstriction) includes four chapters designed to illustrate the potential mechanisms involved in oxygen sensing and hypoxia-induced pulmonary vasoconstriction and hypertension. Part VI (Targeting Ion Channels and Membrane Receptors in Developing Novel Therapeutic Approaches for Pulmonary Vascular Disease) consists five chapters which discuss the translational research involving on membrane receptors, channels and transporters, including their potential as novel drug targets. We hope that Membrane Receptors, Channels and Transporters in Pulmonary Circulation will allow readers to foster new concepts and new collaborations and cooperations among investigators so as to further understand the role of receptors, channels and transporters in lung pathophysiology. The ultimate goal is to identify new mechanisms of disease, as well as new therapeutic targets for pulmonary vascular diseases. An additional outcome should be enhanced understanding of the role of these entities in systemic vascular pathophysiology, since the conference will include researchers and clinicians with interests in both pulmonary and systemic circulations.

A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics (Paperback, 2010 ed.): Pierandrea Borea A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics (Paperback, 2010 ed.)
Pierandrea Borea
R5,716 Discovery Miles 57 160 Ships in 10 - 15 working days

This book, with its 16 chapters, documents the present state of knowledge of the adenosine A receptor. It covers a wide range of information, including data from 3 studies of theoretical, molecular and cellular pharmacology, signal transduction, integrative physiology, new drug discoveries and clinical applications. It fills an important gap in the literature since no alternative source of such information is currently available. Although the A receptor is increasingly being recognized for 3 its increasing number of biological roles throughout the body and many A receptor 3 ligands have proven useful in elucidating peripheral and central pathologies, many issues remain unresolved. Moreover, research activity in this field continues to grow exponentially, resulting in a constant flow of new information. The chapters in this book cover both basic science and the relevant applications and provide an authoritative account of the current status of the field. They have enabled my goal as editor to make "A Adenosine Receptors from Cell Biology to Pharmacology and 3 Therapeutics" an up to date, scientifically excellent, reference source, attractive to basic and clinical scientists alike, a reality. Detailed understanding of the physico-chemical aspects and molecular biology of the A receptor provides a solid basis for its future development as a target for 3 adenosine-based pharmacotherapies (Chapters 2 and 3).

New Challenges for Cancer Systems Biomedicine (Paperback, 2012 ed.): Alberto d'Onofrio, Paola Cerrai, Alberto Gandolfi New Challenges for Cancer Systems Biomedicine (Paperback, 2012 ed.)
Alberto d'Onofrio, Paola Cerrai, Alberto Gandolfi
R3,214 Discovery Miles 32 140 Ships in 10 - 15 working days

The future of oncology seems to lie in Molecular Medicine (MM). MM is a new science based on three pillars. Two of them are evident in its very name and are well known: medical science and molecular biology. However, there is a general unawareness that MM is firmly based on a third, and equally important, pillar: Systems Biomedicine. Currently, this term denotes multilevel, hierarchical models integrating key factors at the molecular, cellular, tissue, through phenotype levels, analyzed to reveal the global behavior of the biological process under consideration. It becomes increasingly evident that the tools to construct such complex models include, not only bioinformatics and modern applied statistics, as is unanimously agreed, but also other interdisciplinary fields of science, notably, Mathematical Oncology, Systems Biology and Theoretical Biophysics.

Biochemistry Behind the Symptoms (Paperback): Emine E. Abali, Roy Carman, Douglas Spicer Biochemistry Behind the Symptoms (Paperback)
Emine E. Abali, Roy Carman, Douglas Spicer
R1,279 Discovery Miles 12 790 Ships in 12 - 17 working days

Biochemistry Behind the Symptoms takes a problem-based approach to understanding and applying biochemistry for superior clinical outcomes. Organized around the common symptoms encountered by clinicians, this engaging text clarifies the connections between foundational science and clinical manifestations to help users form confident diagnoses throughout their clerkship and beyond. Each chapter explores the biochemical concepts behind underlying causes and demonstrates their ties to presenting symptoms through 5 realistic patient cases. Accompanying questions encourage discussion and guide users in building accurate differential diagnoses. Ideal for peer-to-peer learning environments or independent study, this practical approach strengthens users' application of fundamental knowledge and ensures the long-term retention essential to clinical success. 50 Patient Cases emphasize the biochemical concepts behind common patient symptoms through problem-based learning. Clinical Impression sections encourage critical thinking and train students step by step in building effective differential diagnoses. Basic Science Correlations in each Patient Case clarify the biochemical concepts underlying diagnosis with an engaging question-and-answer format. High-Yield Concepts summarized after each Patient Case reinforce students' comprehension of essential chapter concepts. Digital Animations immerse students in biochemical processes to enrich their understanding and diagnostic confidence.

RNP Particles, Splicing and Autoimmune Diseases (Paperback, 1998 ed.): Johannes Schenkel RNP Particles, Splicing and Autoimmune Diseases (Paperback, 1998 ed.)
Johannes Schenkel
R1,522 Discovery Miles 15 220 Ships in 10 - 15 working days

The first insights into the site and mechanisms of RNA process- ing to functional mRNA in eukaryotic cells came from the group of Georgiev (Lukanidin et al. 1972) who demonstrated the association of rapidly labelled, heterogeneous nuclear RNA (hnRNA) with a limited number of specific proteins in the cell nucleus. These "informofers", i. e. packaged precursors of mRNA (pre-mRNA or hnRNA), are in a form presumably amenable to the action of nucleases. With the availability of better analytical techniques, the considerable heterogeneity of hnRNA associated proteins was revealed (Niessing and Sekeris 1970), suggesting a role that was more composite, rather than solely structural, for these proteins. Later studies investigated the RNA binding behavior of these proteins (Schenkel et al. 1988, 1989; Wilk et al. 1983). For a long time, the small nuclear RNAs, well characterized with respect to primary structure (reviewed by Reddy and Busch 1983), were naively ignored regarding their function. Several events then set the stage for a detailed study of the intricate mechanisms of the splicing process and other steps involved in hnRNA processing: (1) The demonstration of a second class of nuclear ribonucleoproteins (RNPs), composed of small nuclear RNAs (snRNAs) and another characteristic group ofheterogene- ous proteins (Lerner et al. 1980; Guialis et al. 1983); (2) the detec- tion of the association of snRNPs with hnRNPs by virtue of base pairing between hnRNA and snRNA (Flytzanis et al.

Clinical Chemistry (Paperback, 9th edition): William J. Marshall, Marta Lapsley, Andrew Day, Kate Shipman Clinical Chemistry (Paperback, 9th edition)
William J. Marshall, Marta Lapsley, Andrew Day, Kate Shipman
R1,535 Discovery Miles 15 350 Ships in 9 - 15 working days

Clinical Chemistry considers what happens to the body's chemistry when affected by disease. It provides introductory coverage of the scientific basis for biochemistry tests routinely used in medicine - including tests for the assessment of organ function, diagnosis and monitoring disease activity and therapy efficacy. Each topic area begins with a concise description of the underlying physiological and biochemical principles and then applies them to patient investigation and management. The regular use of case histories helps further emphasise clinical relevance and chapter key points, as well as provide a useful starting point for examination revision. The clear and engaging writing style appreciated by generations of readers has been retained in this latest (ninth) edition, while the content has been thoroughly updated throughout. The approach and scope of this trusted text makes it ideal for integrated medical curricula, for medical training and for students and practitioners of clinical and biomedical science. The complementary eBook version (with the printed book), including additional cases and self-assessment material, completes this superb learning package. Updated to incorporate the latest changes in practice - including new tests and the most recent evidence-based guidance 'Light bulb' sections give practical advice and clarify difficult concepts or potential pitfalls New 'Red flag' boxes highlight the results which should cause immediate concern to clinicians Updated references to core guidelines reflect latest best practice (Print) includes complete, downloadable eBook on Student Consult Also BONUS materials - interactive clinical cases and MCQs - to reinforce interpretive skills, check understanding and aid exam preparation Updated to incorporate the latest changes in practice - including new tests and the most recent evidence-based guidance - plus a new chapter on clinical chemistry in pediatrics. Figures, tables, boxes, and case studies aid understanding and learning. 'Light bulb' sections give practical advice and clarify difficult concepts or potential pitfalls. New 'Red flag' boxes highlight the results which should cause immediate concern to clinicians. Updated references to core guidelines reflect latest best practice. BONUS materials on Student Consult include interactive clinical cases and MCQs - to reinforce interpretive skills, check understanding and aid exam preparation. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Mehrschicht-CT - Ein Leitfaden (German, Hardcover, 2008 ed.): Roland Bruning, Axel Kuttner, Thomas Flohr Mehrschicht-CT - Ein Leitfaden (German, Hardcover, 2008 ed.)
Roland Bruning, Axel Kuttner, Thomas Flohr
R2,314 Discovery Miles 23 140 Ships in 12 - 17 working days

Dieses Buch bietet strukturierte und aktuellste Informationen zu allen Routineanwendungen der Mehrschicht- (Multidetektor-) Computertomographie, auch der neuesten Gerategeneration (Dual-Slice bzw. Dual-Layer).

Es enthalt ausfuhrliche Kapitel zum technischen Hintergrund und behandelt systematisch alle wichtigen Organsysteme: Herz, Kopf und Hals, Thorax und Abdomen mit parenchymalen Organen und Gastrointestinaltrakt.

Jedes Protokoll wird tabellarisch prasentiert; dies ermoglicht dem Benutzer einen schnellen Uberblick uber die gewunschten Anwendungen und die notwendigen Einstellungen des CT-Gerats.

Alle Beitrage sind verfasst von anerkannten Experten auf dem Gebiet der CT, die nicht nur ihre reiche klinische Erfahrung in jedem Anwendungsgebiet einbringen, sondern auch Anleitungen fur Indikationen, Arbeitsablauf, Nachbearbeitung und Rekonstruktionsalgorithmen erarbeitet haben."

POF-Handbuch - Optische Kurzstrecken-UEbertragungssysteme (German, Hardcover, 2., bearb. u. erg. Aufl. 2007): Olaf Ziemann,... POF-Handbuch - Optische Kurzstrecken-UEbertragungssysteme (German, Hardcover, 2., bearb. u. erg. Aufl. 2007)
Olaf Ziemann, Jurgen Krauser, Peter E. Zamzow, Werner Daum
R6,229 Discovery Miles 62 290 Ships in 12 - 17 working days

Ein halbes Jahrzehnt nach der ersten Auflage erscheint das Buch nun komplett neu bearbeitet und aktualisiert in doppeltem Umfang. Die Neugestaltung wurde vom Polymerfaser-Anwendungszentrum der FH Nurnberg geleitet, wobei viele eigene Messungen zur Bandbreite, zu den optischen Eigenschaften und zu moglichen Ubertragungskapazitaten an mehr als einem Dutzend optischer Dickkernfasern wiedergegeben werden.

Noch vor wenigen Jahren war die POF eine Nischentechnologie. Inzwischen fahren viele Millionen PKW mit POF-Bordnetzen. Mit dem rasanten Anstieg der privaten Breitbandanschlusse und dem gleichzeitigen Anwachsen der Bitraten, vor allem durch IP-TV getrieben, wird die POF auch mehr und mehr in Gebaudenetzen eingesetzt. Das Handbuch zeigt vorhandene kommerzielle Losungen ebenso wie das Potenzial fur zukunftige Anwendungen. Optische Wellenleiter, Polymerfasern als preiswerte Sensoren und vielfach parallele Datenverbindungen sind weitere Anwendungsfelder, die beschrieben werden. Uber 1000 Abbildungen, 600 Literaturstellen und zahlreiche Tabellen vervollstandigen den Text."

Artrite reumatoide e spondiloentesoartriti - Diagnostica per immagini ed imaging follow-up (Italian, Hardcover, 2007 ed.):... Artrite reumatoide e spondiloentesoartriti - Diagnostica per immagini ed imaging follow-up (Italian, Hardcover, 2007 ed.)
Giacomo Garlaschi, Fabio Martino
R1,544 Discovery Miles 15 440 Ships in 10 - 15 working days

Le recenti evoluzioni tecnologiche nella diagnostica per immagini hanno consentito gli cogliere le alterazioni anatomiche e funzionali che caratterizzano la fase di esordio delle artropatie degenerative ed infiammatorie. Nell'ambito di queste ultime, in particolare, l'imaging risulta non solo fondamentale nella diagnosi dello stadio early delle artriti ma anche nella definizione della loro evoluzione e della risposta al moderno trattamento terapeutico. La valutazione di una nuova semeiologia imaging, che si avvale notevolmente dell'impiego di mdc in relazione sia al power Doppler sia alla risonanza magnetica, ha consentito di restringere il gap tra istologia ed imaging nella diagnostica reumatologica.

Grundlagen der Technischen Dokumentation - Anleitungen verstandlich und normgerecht erstellen (German, Hardcover, 1. Auflage):... Grundlagen der Technischen Dokumentation - Anleitungen verstandlich und normgerecht erstellen (German, Hardcover, 1. Auflage)
Lars Kothes
R3,135 Discovery Miles 31 350 Ships in 12 - 17 working days

Technische Dokumentation ist die Aufbereitung und Publikation technischer Sachverhalte und Abl ufe. Dabei spielen die Strukturierung der Information, die pr gnante Formulierung von Texten, die visuelle Aufbereitung und die Wahl des Mediums eine wesentliche Rolle. Die Ber cksichtigung von Gesetzen, Normen und Richtlinien kann dazu beitragen, Hersteller vor Schadensersatzforderungen zu sch tzen. Das Buch vermittelt grundlegendes Wissen f r die externe Technische Dokumentation von Maschinen, Anlagen und anderen technischen Produkten.

Peptide Synthesis and Applications (Hardcover, 2005 ed.): John Howl Peptide Synthesis and Applications (Hardcover, 2005 ed.)
John Howl
R2,950 Discovery Miles 29 500 Ships in 10 - 15 working days

Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.

Darmgesundheit und Mikrobiota - Ein Überblick über die Bedeutung der Darmbakterien für die Gesundheit (Paperback, 2015 ed.):... Darmgesundheit und Mikrobiota - Ein Überblick über die Bedeutung der Darmbakterien für die Gesundheit (Paperback, 2015 ed.)
Dirk Haller, Gabriele Hörmannsperger
R409 Discovery Miles 4 090 Ships in 12 - 17 working days

Dirk Haller und Gabriele Hörmannsperger geben einen Überblick über die zentrale Rolle des Darms und seiner Bewohner für die Gesundheit und vermitteln zusätzlich einen ersten Eindruck von den komplexen und dynamischen Interaktionen zwischen D+armbakterien und Wirt. Denn Forschungsergebnisse der letzten Jahre weisen darauf hin, dass die lange unbeachteten Darmbakterien (intestinale Mikrobiota) eine unerwartet zentrale Rolle für die Aufrechterhaltung der Gesundheit einnehmen. Die Forschung beschäftigt sich aktuell intensiv damit, die Grundlagen für ein funktionierendes und gesundheitsförderndes mikrobielles Ökosystem zu identifizieren. Dieses Wissen kann zukünftig für die Entwicklung gezielter Maßnahmen zur Prävention und Therapie Mikrobiota-assoziierter Erkrankungen eingesetzt werden.

Introduction to Oncogenes and Molecular Cancer Medicine (Paperback, 1998 ed.): Dennis W. Ross Introduction to Oncogenes and Molecular Cancer Medicine (Paperback, 1998 ed.)
Dennis W. Ross
R1,567 Discovery Miles 15 670 Ships in 10 - 15 working days

Scientists now understand that cancer is a genetic disease and cutting -edge molecular therapies are making their way from the laboratory into clinical practice. Introduction to Oncogenes and Molecular Cancer Medicine provides the physician with a solid understanding of molecular biology and its applications for the diagnosis and treatment of cancer. The book reviews the basic molecular principles and the basic principles of cancer medicine, including controls of cell growth and senescence, carcinogenesis, tumorogenesis, and epidemiology. The second part of the book gives clinical examples to demonstrate the basic science principles, including chapters on leukemia, colon cancer, and breast cancer. A chapter on molecular diagnostics and screening plus a chapter on new molecular anti-cancer therapies give the reader a look at current cutting-edge therapies as well as as the future of molecular cancer medicine. A useful glossary defines new terminology at-a-glance. Introduction to Oncogenes and Molecular Cancer Medicine is for all physicians seeking a better understanding of the modern molecular principles of cancer medicine. Written in a user-friendly, conversational format, this text will be welcomed by all physicians eager to sharpen their own understanding of molecular cancer medicine as well as to help them provide patients with balanced information on the advances and limitations of current treatment options.

Vitamin C - The state of the art in disease prevention sixty years after the Nobel Prize (Paperback, illustrated edition):... Vitamin C - The state of the art in disease prevention sixty years after the Nobel Prize (Paperback, illustrated edition)
Rodolfo Paoletti, Helmut Sies, Joachim Bug, Enzo Grossi, Andrea Poli
R1,506 Discovery Miles 15 060 Ships in 10 - 15 working days

Vitamin C, or ascorbic acid, has a long and multifaceted scientific history. In 1937, the Nobel Prize for Physiology and Medicine was awarded to Albert Szent-Gyorgyi'in recognition of his discoveries concerning the biological oxida tion processes with special reference to vitamin C', and the Nobel Prize for Chemistry was shared by Sir Norman W. Haworth, who was the first to synthesize the vitamin. Vitamin C is a potent antioxidant, and this action represented the theoretical basis for various lines of investigation on this molecule in which the potential role of ascorbic acid in the prevention and treatment of a series of dis eases, whose pathogenesis is linked to an excess of free radicals such as athero sclerosis and cancer, have been examined. These data have been analyzed in detail by experts in biochemistry, epidemi ology, and preventive and clinical medicine in the International Symposium Vitamin C, the state of the art in disease prevention sixty years after the Nobel Prize, held in Monte Carlo from October 31 to November 1, 1997, under the aus pices and the scientific endorsement of the Nutrition Foundation of Italy and with the financial support of Bracco SpA and Merck."

Clinical Applications of PCR (Paperback, 1998 ed.): Y. M. Dennis Lo Clinical Applications of PCR (Paperback, 1998 ed.)
Y. M. Dennis Lo
R4,468 Discovery Miles 44 680 Ships in 10 - 15 working days

The polymerase chain reaction (PCR) is one of the most important molecular biological methods ever devised, with numerous applications to cli- cal molecular medicine. Since its description in 1985, PCR has undergone tremendous improvements, and many variations on the basic PCR theme have been published. With such a large volume of PCR-related literature, a clinical scientist wishing to use the technique will have a difficult task loc- ing the relevant information to implement it effectively. There is thus clearly a need for an up-to-date volume with detailed protocols to facilitate the setting up of those techniques most relevant to clinical applications. Unlike some other books on this topic, Clinical Applications of PCR includes only methods that are of direct relevance in clinical settings. The book is organized in three parts: an introductory section, a section on general methodology, and a final section with specific clinical applications. The first section covers the basic principles of PCR and is most useful to those new to molecular diagnosis. The next chapter includes useful tips for setting up a PCR laboratory. Section 2 then outlines some of the most commonly used PCR-based techniques in molecular diagnosis. Section 3 includes carefully chosen examples that represent typical applications of PCR in diverse clinical fields, encompassing hematology, oncology, genetics, and microbiology.

Catalytic RNA (Paperback, Softcover reprint of the original 1st ed. 1997): Fritz Eckstein, David M.J. Lilley Catalytic RNA (Paperback, Softcover reprint of the original 1st ed. 1997)
Fritz Eckstein, David M.J. Lilley
R2,967 Discovery Miles 29 670 Ships in 10 - 15 working days

In recent years, unprecedented advances in many aspects of the molecular biology of nucleic acids have been witnessed. The area of RNA chemistry has undergone a kind of explosion, with a huge interest in RNA-mediated catalysis. At the same time, our structural understanding of DNA-protein interactions has increased enormously, and the related area of RNA-protein interactions is beginning to gather pace. This softcover edition from the successful series Nucleic Acids and Molecular Biology is devoted to the structure and mechanism of ribozymes, and their potential exploitation. The subject has both important evolutionary implications and potential practical application in the development of therapeutic agents for diseases such as AIDS.

Roentgenthorax auf Intensivstationen (German, Hardcover, 2., korr. u. erw. Aufl. 2004): Gunter Luska Roentgenthorax auf Intensivstationen (German, Hardcover, 2., korr. u. erw. Aufl. 2004)
Gunter Luska; Contributions by Heiner Boetticher, W Kuckelt, R. Sassen, L Schwarze
R1,958 Discovery Miles 19 580 Ships in 12 - 17 working days

Rontgenthoraxaufnahmen richtig interpretieren

Thoraxaufnahmen, die auf der Intensivstation aufgenommen werden, unterscheiden sich in der Aufnahmetechnik und in den veranderten physiologischen und anatomischen Verhaltnissen von Standard-Thoraxaufnahmen, die am Rasterwandstativ angefertigt werden. Die Interpretation dieser Bilder bereitet selbst erfahrenen Radiologen und Intensivmedizinern haufig Schwierigkeiten.

Der Weg zur korrekten Interpretation: - Rontgen- und Aufnahmetechnik - Strahlenschutz und -belastung - Klinische Problematik und Interpretation von Thoraxaufnahmen auf der Intensivstation.

Neu in der 2. Auflage:

Bildmaterial moderner Aufnahmeverfahren

Indikationsstellung fur CT-Aufnahmen

Vergleich von Projektionsradiographie und Schnittbildradiographie und mogliche Pitfalls

Ein Praxisbuch von Radiologen, Intensivmedizinern und Medizinphysikern zum Lernen und Nachschlagen. Ein Muss fur jeden auf der Intensivstation tatigen Arzt "

Visualization in Biomedical Computing - 4th International Conference, VBC '96, Hamburg, Germany, September 22 - 25, 1996,... Visualization in Biomedical Computing - 4th International Conference, VBC '96, Hamburg, Germany, September 22 - 25, 1996, Proceedings (Paperback, 1996 ed.)
Karl H. Hoehne, Ron Kikinis
R3,047 Discovery Miles 30 470 Ships in 10 - 15 working days

This book constitutes the refereed proceedings of the 4th International Conference on Visualization in Biomedical Computing, VBC '96, held in Hamburg, Germany, in September 1996.
The 73 revised full papers presented were selected from a total of 232 submissions. The book reports the state of the art in the field of computer based visualization in medicine and biology. The papers are organized in sections on visualization; image processing; segmentation; registration; brain: description of shape; brain: characterization of pathology; brain: visualization of function; simulation of surgery and endoscopy; image guided surgery and endoscopy.

Tauchmedizin - Barotrauma Gasembolie - Dekompression Dekompressionskrankheit Dekompressionscomputer (German, Hardcover, 5th 5.,... Tauchmedizin - Barotrauma Gasembolie - Dekompression Dekompressionskrankheit Dekompressionscomputer (German, Hardcover, 5th 5., Vollst. Uberarb. Aufl. 2002 ed.)
A.A Buhlmann, E B Voellm, P Nussberger
R2,658 Discovery Miles 26 580 Ships in 12 - 17 working days

Bereits in der 5. Auflage erfolgreich! Sowohl Grundlagen der Tauchmedizin als auch Ergebnisse der experimentellen tauchmedizinischen Forschung werden behandelt. Die Probleme des Tieftauchens mit Gasgemischen, des Sporttauchens mit Luft im konventionellen Bereich und der stundenlangen UEberexposition der Caissonarbeiter in Tunneln werden abgehandelt. Seit 1985 wird bei Gasembolie, Dekompressionskrankheit des Gehirns/Ruckenmarks und Innenohrschaden die Behandlung mit hyperbarem Sauerstoff (HBO) angewandt; die Ergebnisse werden mit aussagekraftigen Zahlen belegt. Das Rechenmodell ZH-L8 ADT, bei Tauchcomputern der jungsten Generation in Anwendung, wird beschrieben. Ein aussagefahiger UEberblick uber praktische Tauchmedizin, experimentelle Forschung und Aufbau und Funktion von Dekompressionscomputern!

Facing the Pancreatic Dilemma - Update of Medical and Surgical Pancreatology (Paperback): Paolo Pederzoli Facing the Pancreatic Dilemma - Update of Medical and Surgical Pancreatology (Paperback)
Paolo Pederzoli; Edited by (associates) M. Falconi; Edited by Giorgio Cavallini, Claudio Bassi
R2,994 Discovery Miles 29 940 Ships in 10 - 15 working days

This volume is a compendium of the lectures, presentations, and workshops of the International Congress entitled "Facing the Pancreatic Dilemma" and of the 17th Meeting of the Italian Association for the Study of the Pancreas, held in Verona on 16 -19 June 1993. Pancreatology is still a relatively young science. Many pathophysiological aspects of pancreatic disease are as yet obscure, and a fair number of the etio pathogenetic mechanisms adduced are no more than hypothetical. We have therefore chosen to compare and contrast in a single volume the various hypo theses and interpretations put forward by leading experts in the field. In view of the swift evolution of this branch of medical science, it is sound policy to bear in mind that yesterday's heresies have become today's orthodoxy, and that todays's heresies may well turn out to be accepted orthodoxy in a not too distant future. The various "pancreatic dilemmas" are addressed systematically in these pages, and we believe that the book will prove an invaluable tool for the special ist and for any physician dealing with pancreatic disease. The book also represents a tribute by the Verona School of Pancreatology to the memory of Prof. L. A. Scuro, founder of the School and one of the outstanding Italian pioneers of pancreatology."

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