Electrical Impedance: Principles, Measurement, and Applications provides a modern and much-needed overview of electrical impedance measurement science and its application in metrology, sensor reading, device and material characterizations. It presents up-to-date coverage of the theory, practical methods, and modeling. The author covers the main impedance measurement techniques, stressing their practical application. The book includes a large set of measurement setup schematics, and diagrams and photos of standards and devices. It also offers an extensive list of references to both historical and recent papers on devices, methods, and traceability issues. Reviews the main definitions of the quantities related to impedance, some theorems of particular interest, the issue of impedance representation, and introduces the problem of impedance definition Lists devices, appliances, circuits, and instruments employed as building blocks of impedance measurement setups Classifies the main impedance measurement methods, including details on their implementation when a specific impedance definition is chosen Discusses the increasing use of mixed-signal electronics in impedance measurement setups Covers applications including details on the measurement of electromagnetic properties of materials Introduces impedance metrology, including artifact impedance standards, and the realization and reproduction of SI impedance units

The key to the successful development of distributed measurement and control systems is the communications link. Emphasising the importance of communications standards, this topical text describes and discusses serial data highways developed for measurement and control applications. Such standards demand conformity to a protocol which ensures reliable transmissions between digital field devices, using a common communications interface. This comprehensive overview of the large family of data highways currently in use addresses all aspects of the practical implementation of industrial control systems. Features include:

• Up-to-date overview of serial networking technology for measurement and control applications.
• Review of the fundamental concepts and relative merits of twelve serial network communication standards.
• A valuable insight into a wide range of market sectors where proprietary, national and international standards now apply.
• Discussion of each established or evolving serial data highway in the context of its application.

This text is an invaluable reference source for engineers and product designers in measurement and control seeking to increase their awareness of developments in the complete range of market sectors. For anyone contemplating the development of a communications standard, this will prove an indispensable frame of reference. In addition to providing detailed information about the serial bus, this unique book will furnish advanced students of electronic and electrical engineering with a broader view of their subject and encourage a more product-oriented approach. Serial Networked Field Instrumentation forms part of the Wiley Series in MeasurementScience and Technology. Chief Editor: Peter Sydenham Australian Centre for Test and Evaluation, University of South Australia. This series was founded to coincide with the recognition of measurement science and instrument technology as fields with their own scholarship and techniques.

Although elemental semiconductors such as silicon and germanium are standard for energy dispersive spectroscopy in the laboratory, their use for an increasing range of applications is becoming marginalized by their physical limitations, namely the need for ancillary cooling, their modest stopping powers, and radiation intolerance. Compound semiconductors, on the other hand, encompass such a wide range of physical and electronic properties that they have become viable competitors in a number of applications. Compound Semiconductor Radiation Detectors is a consolidated source of information on all aspects of the use of compound semiconductors for radiation detection and measurement. Serious Competitors to Germanium and Silicon Radiation Detectors Wide-gap compound semiconductors offer the ability to operate in a range of hostile thermal and radiation environments while still maintaining sub-keV spectral resolution at X-ray wavelengths. Narrow-gap materials offer the potential of exceeding the spectral resolution of germanium by a factor of three. However, while compound semiconductors are routinely used at infrared and optical wavelengths, their development in other wavebands has been plagued by material and fabrication problems. So far, only a few have evolved sufficiently to produce commercial detection systems. From Crystal Growth to Spectroscopic Performance Bringing together information scattered across many disciplines, this book summarizes the current status of research in compound semiconductor radiation detectors. It examines the properties, growth, and characterization of compound semiconductors as well as the fabrication of radiation sensors, with particular emphasis on the X- and gamma-ray regimes. It explores the limitations of compound semiconductors and discusses current efforts to improve spectral performances, pointing to where future discoveries may lie. A timely resource for the established researcher, this book serves as a comprehensive and illustrated reference on material science, crystal growth, metrology, detector physics, and spectroscopy. It can also be used as a textbook for those new to the field of compound semiconductors and their application to radiation detection and measurement.

The importance of proper geometric dimensioning and tolerancing as a means of expressing the designer's functional intent and controlling the inevitable geometric and dimensional variations of mechanical parts and assemblies, is becoming well recognized. The research efforts and innovations in the field of tolerancing design, the development of supporting tools, techniques and algorithms, and the significant advances in computing software and hardware all have contributed to its recognition as a viable area of serious scholarly contributions. The field of tolerancing design is successfully making the transition to maturity where deeper insights and sound theories are being developed to offer explanations, and reliable implementations are introduced to provide solutions. Machine designers realized very early that manufacturing processes do not produce the nominal dimensions of designed parts. The notion of associating a lower and an upper limit, referred to as tolerances, with each dimen sion was introduced. Tolerances were specified to ensure the proper function of mating features. Fits of mating features included clearances, location fits, and interference fits, with various sub-grades in each category assigned a tolerance value depending on the nominal size of the mating features. During the inspection process, a part is rejected if a dimension fell outside the specified range. As the accuracy requirements in assemblies became tighter, designers had to consider other critical dimensions and allocate tolerances to them in order to ensure the assembly's functionality."

A great deal of research is being done in the areas of artificial vision and neural networks. Although much of this research has been theoretical in nature, many of the techniques developed through these efforts are now mature enough for use in practical applications. Automated Visual Inspection Using Artificial Neural Networks explains the application of recently emerging technology in the areas of artificial vision and neural networks to automated visual inspection. The information is organised in a clear, informative manner, bridging the gap between theoretical research and practical application. Significantly this book includes: * broad coverage of all aspects of the automated visual inspection problem, * details of the HAVENET neural network and the CAMERA vision model, and * detailed descriptions of practical applications of intelligent visual inspection.

Planning, measuring, and paying attention to details form the basis for all successful engineering operations. Measurements pervade everything we do and must be viewed from a systems perspective. A comprehensive all-encompassing guide to measurements, Handbook of Measurements: Benchmarks for Systems Accuracy and Precision focuses on high-level engineering computations essential for benchmarks and technical innovation. The book uses a systems framework and a technically rigorous approach to systems linking of measurements-an approach that sets it apart from other handbooks. The popular saying "measure twice and cut once" bears out the importance of measurements in human endeavors. This handbook covers both qualitative and quantitative topics of measurement. It opens with a chapter on the fundamentals of measurement and includes coverage of human-centric measurements, such as measurement of personnel productivity and contractor performance. It concludes with three appendices on measurement, references, conversion factors, equations, formulas, and statistics for measurement. It is well understood that humans cannot manage anything that cannot be measured. All elements involved in our day-to-day decision making involve some form of measurement, whether in the kitchen, retail, sports, service operations, geographical exploration, health care delivery, worker productivity, clothing design, engineering product design, or space craft launching. Measuring an attribute of a system and then analyzing it against some standard, some specification, some best practice, or some benchmark empower a decision maker to take appropriate and timely actions. This book gives you a guide for sustainable practices to ensure accurate measurements, helping you make decisions backed by metrics.

Gives a comprehensive view on the nanomaterials used in plasmonic optical fiber biosensors Includes synthesis, characterization, and usage for detection of different analytes Discusses trends in the design of wavelength-based optical fiber sensors Reviews micro- and nanostructured biosensing devices Explores application of plasmonic sensors in the biosensing field

The rapidly emerging fields of nanotechnology and nano-fabrication have enabled the creation of new sensors with dramatic improvements in sensitivity and range, along with substantial miniaturization. And, although there are many books on nanotechnology, recent advances in micro and nano-scale sensors and transducers are not adequately represented in most books. This book fills that gap. Micro- and Nano-Scale Sensors and Transducers provides a summary of the state of the art in sensor and transducer technology. Teaching you how to make more informed selections of sensors or transducers for particular applications, it describes the differences between new sensor and transducer technologies based on nanotechnology and nano-fabrication and the older or "classical" sensor technologies. The book presents the new structures of pressure sensors being used in such applications as mechanical pressure sensing, gas pressure sensing, and atmospheric pressure sensing. It illustrates the novel structures and characteristics of new motion and acceleration sensors. Describing highly sensitive miniature gas and smoke sensors based on nano-structured electrodes, the book presents novel techniques for detecting atmospheric moisture and moisture inside small electronic components. It also covers applications of optoelectronic and photonic sensors. The book examines multi-purpose biological and chemical analysis devices where each device is fully contained in one integrated circuit (Lab on a Chip) as well as other advanced chemical and biological sensors. It describes electric, magnetic, and RF / microwave sensors and their applications and also considers integrated sensor / actuator units and special-purpose sensors. Each chapter in the book includes a set of quizzes / short questions, along with answers.

Integrating aspects of engineering, application physics, and medical science, Solid-State Radiation Detectors: Technology and Applications offers a comprehensive review of new and emerging solid-state materials-based technologies for radiation detection. Each chapter is structured to address the current advantages and challenges of each material and technology presented, as well as to discuss novel research and applications. Featuring contributions from leading experts in industry and academia, this authoritative text: Covers modern semiconductors used for radiation monitoring Examines CdZnTe and CdTe technology for imaging applications including three-dimensional capability detectors Highlights interconnect technology for current pixel detectors Describes hybrid pixel detectors and their characterizations Tackles the integrated analog signal processing read-out front ends for particle detectors Considers new organic materials with direct bandgap for direct energy detection Summarizes recent developments involving lanthanum halide and cerium bromide scintillators Analyzes the potential of recent progress in the field of crystallogenesis, quantum dots, and photonics crystals toward a new concept of x- and gamma-ray detectors based on metamaterials Explores position-sensitivity photomultipliers and silicon photomultipliers for scintillation crystals Solid-State Radiation Detectors: Technology and Applications provides a valuable reference for engineers and scientists looking to enhance the performance of radiation detector technology for medical imaging and other applications.

Laser-Based Optical Detection of Explosives offers a comprehensive review of past, present, and emerging laser-based methods for the detection of a variety of explosives. This book: Considers laser propagation safety and explains standard test material preparation for standoff optical-based detection system evaluation Explores explosives detection using deep ultraviolet native fluorescence, Raman spectroscopy, laser-induced breakdown spectroscopy, reflectometry, and hyperspectral imaging Examines photodissociation followed by laser-induced fluorescence, photothermal methods, cavity-enhanced absorption spectrometry, and short-pulse laser-based techniques Describes the detection and recognition of explosives using terahertz-frequency spectroscopic techniques Each chapter is authored by a leading expert on the respective technology, and is structured to supply historical perspective, address current advantages and challenges, and discuss novel research and applications. Readers are left with an in-depth understanding and appreciation of each technology's capabilities and potential for standoff hazard detection.

Written for an advanced-level course in digital systems design, DIGITAL SYSTEMS DESIGN USING VHDL integrates the use of the industry-standard hardware description language VHDL into the digital design process. Following a review of basic concepts of logic design in Chapter 1, the author introduces the basics of VHDL in Chapter 2, and then incorporates more coverage of VHDL topics as needed, with advanced topics covered in Chapter 8. Rather than simply teach VHDL as a programming language, this book emphasizes the practical use of VHDL in the digital design process. For example, in Chapter 9, the author develops VHDL models for a RAM memory and a microprocessor bus interface; he then uses a VHDL simulation to verify that timing specifications for the interface between the memory and microprocessor bus are satisfied. The book also covers the use of CAD tools to synthesize digital logic from a VHDL description (in Chapter 8), and stresses the use of programmable logic devices, including programmable gate arrays. Chapter 10 introduces methods for testing digital systems including boundary scan and a built-in self-test.

Handbook of Optical Sensors provides a comprehensive and integrated view of optical sensors, addressing the fundamentals, structures, technologies, applications, and future perspectives. Featuring chapters authored by recognized experts and major contributors to the field, this essential reference: Explains the basic aspects of optical sensors and the principles of optical metrology, presenting a brief historical review Explores the role of optical waveguides in sensing and discusses sensor technologies based on intensity and phase modulation, fluorescence, and plasmonic waves Describes wavefront sensing, multiphoton microscopy, and imaging based on optical coherence tomography Covers optical fiber sensing, from light guiding in standard and microstructured optical fibers to sensor multiplexing, distributed sensing, and fiber Bragg grating Offers a broad perspective of the field and identifies trends that could shape the future, such as metamaterials and entangled quantum states of light Handbook of Optical Sensors is an ideal resource for practitioners and those seeking optical solutions for their specific needs, as well as for students and investigators who are the intellectual driving force of optical sensing.

Overview International System of Units (SI) (Print On-Demand Edition) is a one-of-a-kind book. It provides detailed information on the metric system, its origin, history, and how the base and derived units were established. The book has four chapters (Measurement Systems, the International System of Units, Metrication in the United States, and United States Metric Association), appendices, an afterword, and references. The book is principally aimed at educating students in the United States, but it will also be of interest to anyone who enjoys the popular sciences. This is a Print-On-Demand title. It has a CD-ROM companion (ISBN 978-0-8311-3466-2) for which publication has ceased. Dr. Edmund Isakov. Ph.D., has enjoyed a long and distinguished career in metalworking. He earned his Doctor of Philosophy degree in Mechanical Engineering at the V. Bakul Institute for Superhard Materials (Kiev, Ukraine). He is known for his work in research, development and applications of cuttting tools for milling, turning and boring. Dr. Isakov has authored Mechanical Properties of Work Materials and numerous articles and papers on metalcutting. He holds several U.S. patents and numerous U.S.S.R Inventor's Certificates pertaining to carbide and diamond tools. during nearly two decades at Kennametal, Inc., he became a noted authority on the technical analysis of cutting tools. Dr. Isakov is now an independent consulant and manufacturing sciences writer based in Florida. He is a senior member of SME.Introduction Chapter 1: Measurement Systems Brief history of the English System Brief history of the Metric System Chapter 2: International System of Units (SI) SI Base Units of Measurement SI Derived Units of Measurement Chapter 3: Metrication in the United States Brief history Current usage of the metric units Chapter 4: United States Metric Association (USMA) USMA establishment Brief history Summary of metric usage in the United States Appendix 1: Signatories to the Meter Convention (Treaty of the Meter) Appendix 2: Associate States of the CGPM Appendix 3: CGPM Meetings Appendix 4: Prefixes for Multiples and Submultiples of the SI units Appendix 5: Medals awarded to scientists, after whom the units of measurement are named Appendix 6: Standard Inductor Values Appendix 7: The Sixteen Bronze Statues Appendix 8: Temperature Conversion Formulas References Index - Biographical Names

This book captures the latest results and techniques for cooperative localization and navigation drawn from a broad array of disciplines. It provides the reader with a generic and comprehensive view of modeling, strategies, and state estimation methodologies in that fields. It discusses the most recent research and novel advances in that direction, exploring the design of algorithms and architectures, benefits, and challenging aspects, as well as a potential broad array of disciplines, including wireless communication, indoor localization, robotics, emergency rescue, motion analysis, etc.

 Overview The fifth edition features one completely new chapter covering The Measurement of Geometric Dimensions and Tolerances, while providing comprehensive state-of-the-art treatment of all known dimensional measurement devices and techniques. The Handbook of Dimensional Measurement is a unique resource organized into chapters by gage (gauge) type and function. Individual chapters move from simple to complex, from timeless measurement techniques to the most modern and innovative. As the single best (and most recognized and respected) reference on engineering measurement, the Fifth Edition improves its position as the most comprehensive source for dimensional measurement information available! Features Includes a completely new chapter covering The Measurement of Geometric Dimensions and Tolerances.   Includes an improved and expanded illustration program, with 50 new figures and new digital photographs. Supplements discussions with nearly 600 illustrations, line drawings and photographs. Includes improvements and innovations made by the leading manufacturers of dimensional measurement equipment, hardware, and machinery from the last edition. Describes equipment, hardware, and machinery in explicit narrative detail. Brings all references to national and international standards up-to-date.   Introduction Line Graduated Measuring Instruments Fixed Gages Gage Blocks Comparative Length Measurements with Mechanical and Electronic Indicators Pneumatic Gaging Electronic Gages Engineering Microscopes Optical Projectors Angle Measurements The Measurement of Straightness, Flatness and Perpendicularity The Systems and Applications of Measuring Machines Profile Measurements The Measurement of Roundness and Circular Contours Surface Texture Measurement Screw Thread Gaging and Measurement The Measurement of Gears Process Control Gaging Automated Dimensional Measurements New Developments in Dimensional Measurement The Measurement of Geometric Dimensions and Tolerances Appendix A: Principle Changes and Technological Improvements by Chapter Appendix B: National and International Standards Referenced Index

Localization of transmitters and receiving sensors is achieved by measuring radiation emitted by a source to a set of sensors, which are either on a definite pattern, known as an array, or one randomly located at irregular points, known as a distributed sensor array. This book discusses how to determine the position of sensors and transmit information to a central node, also known as the anchor node. Time of arrival, time difference of arrival, frequency time of arrival, and strength of received signal are also covered. The reader will learn effective algorithms and implementation, as well as numerical examples, with the inclusion of lab experiments. It discusses time synchronization, including the rotating laser beam to measure distance, in detail.

Condition monitoring of electrical machines and drive systems is a vital factor to achieve efficient and profitable operation of a large variety of industrial processes. Similarly, parameter estimation is important for the machine designer, and invaluable to the operator of modern drives implementing various types of controllers. It is also necessary to know the machine parameters for a number of simulation purposes. The chapters in this volume cover recent trends and advances in these and other areas, including sections on on-line and off-line parameter estimation of smooth-air-gap and salient-pole electrical machines, their diagnosis, and condition monitoring. New real-time monitoring devices, vibroacoustic techniques, and the symptoms and possible causes of failures of electrical machines are also discussed. In the book a unified and in-depth physical and mathematical analysis of the various parameter estimators and condition monitoring methods is presented. For this purpose, where possible, space phasor theory is utilized and the most recent and modern developments in the field are incorporated. The book is intended for academic and professional electrical engineers, and all those responsible for the performance, maintenance, and design of electrical machines and drive systems.

Why is knowledge of soil stress and deformation state important for off-road locomotion? How do you measure soil stress and deformation under wheel loads? What are the actual values of stresses and deformation in soil or snow under a passing wheel? Providing answers to these questions and more, Dynamics of Wheel-Soil Systems: A Soil Stress and Deformation-Based Approach is a practical reference for anyone who works with experiment design and data analysis of soil stress and deformation measurements under vehicle load. Based on the author's 15 years of experience in field experimentation on wheel-soil dynamics, the book describes methods and devices for soil stress and deformation measurements and presents numerical data from full-scale field experiments. These methods offer practical solutions to methodological problems that may arise during the design and preparation of field experiments. Provides technical information on measuring, modeling, and optimizing off-road vehicle traction-including a novel method for describing off-road traction Provides rare experimental data on soil stress and deformation under a variety of wheeled and tracked vehicles Supplies solutions for designing, building, and using soil or snow pressure transducers and sensors Compiles original experimental data on soil degradation due to agricultural machinery traffic and soil compaction Explains how to create dynamic models of wheel-soil systems based on experimental data A valuable reference on an important area of terramechanics, this book shows how to analyze and model wheel-soil interactions to create more effective designs for a range of vehicle types.

"John Russ is the master of explaining how image processing gets applied to real-world situations. With Brent Neal, he s done it again in Measuring Shape, this time explaining an expanded toolbox of techniques that includes useful, state-of-the-art methods that can be applied to the broad problem of understanding, characterizing, and measuring shape. He has a gift for finding the kernel of a particular algorithm, explaining it in simple terms, then giving concrete examples that are easily understood. His perspective comes from solving real-world problems and separating out what works in practice from what is just an abstract curiosity."

Tom Malzbender, Hewlett-Packard Laboratories, Palo Alto, California, USA

Useful for those working in fields including industrial quality control, research, and security applications, Measuring Shape is a handbook for the practical application of shape measurement. Covering a wide range of shape measurements likely to be encountered in the literature and in software packages, this book presents an intentionally diverse set of examples that illustrate and enable readers to compare methods used for measurement and quantitative description of 2D and 3D shapes. It stands apart through its focus on examples and applications, which help readers quickly grasp the usefulness of presented techniques without having to approach them through the underlying mathematics.

An elusive concept, shape is a principal governing factor in determining the behavior of objects and structures. Essential to recognizing and classifying objects, it is the central link in manmade and natural processes. Shape dictates everything from the stiffness of a construction beam, to the ability of a leaf to catch water, to the marketing and packaging of consumer products. This book emphasizes techniques that are quantitative and produce a meaningful yet compact set of numerical values that can be used for statistical analysis, comparison, correlation, classification, and identification.

Written by two renowned authors from both industry and academia, this resource explains "why" users should select a particular method, rather than simply discussing how to use it. Showcasing each process in a clear, accessible, and well-organized way, they explore why a particular one might be appropriate in a given situation, yet a poor choice in another. Providing extensive examples, plus full mathematical descriptions of the various measurements involved, they detail the advantages and limitations of each method and explain the ways they can be implemented to discover important correlations between shape and object history or behavior. This uncommon assembly of information also includes sets of data on real-world objects that are used to compare the performance and utility of the various presented approaches.

"[Contains] more lengthy mathematical derivations than most {comparable books] ... for arrays, provides for a unique, stand-alone mathematical description that can be adopted by anyone trying to communicate the theoretical foundation for their array design...has insights from a practitioner that are unique. The MATLAB (R) scripts alone are worth the price." -Daniel C. Ross, Ph. D, Northrop Grumman Corporation Electronically Scanned Arrays: MATLAB (R) Modeling and Simulation is considered the first book to provide comprehensive modeling/simulation programs used to design and analyze Electronically Scanned Arrays (ESA), a key technology internationally in the scientific and engineering communities. Several books have been written about ESAs, but most cover only fundamental theory. Few, if any, provide the insightful, easy-to-use simulation tools found in this book. Obviously, MATLAB (R) is one of the greatest tools available for exploring and understanding science and engineering concepts, and we use MATLAB functions to easily and instantly calculate ESA patterns. However, to achieve a truly insightful and in-depth analysis of subarray architectures, conformal arrays, etc., it is imperative that users first develop a firm grasp of ESA fundamentals. Covers largely unexplored topics, such as reliability aspects and the application of ESAs in space This volume helps readers build that elemental understanding of how ESAs work. It also provides code to run as an aid, so that readers don't have to start from scratch. The book expands on ESA principles and provides a modeling framework, using MATLAB to model applications of ESAs (i.e. pattern optimization, space-based applications, and reliability analysis). Presented code serves as an excellent vehicle to help readers master the analysis and simulation of ESAs. Exploring how difficult problems can be simplified with short, elegant solutions, this is an invaluable resource for students and others new to ESAs, as well as experienced practicing engineers who model ESAs at the systems level.

First volume covers the issues related to the components and systems of transport machines. Design issues of machine elements operating in extreme conditions are also addressed. Covers the dynamics of hydraulic, electro-hydraulic and mechanical-hydraulic systems. Examines selected technical and economic issues of gas transport. Covers topics of modelling of production processes with the transport of products.

This book forms the third part of the "Handbook of Measurement Science" series. While the first two volumes dealt with the theoretical and practical fundamentals of measurement science, this third volume concentrates upon the factors which are responsible for the emergence of new measurement systems. The legal aspects of measurement, the many uses of measurement systems and the recent advances in design and manufacturing techniques are all explored in depth. Emphasis is also given to the new technologies which are influencing measurement systems such as microelectronics, fibre optics and biosensors.

Fundamental to the control of mechatronic devices, the servomechanism applies feedback from the device in question to regulate its position, velocity, or some other physical attribute. Successful mastery of servo control requires an understanding of a wide range of engineering disciplines, making it difficult and time-consuming to master it all-and even harder to find an all-encompassing guide that shows you how. DC Servos: Application and Design with MATLAB (R) is designed and written with this problem in mind. It breaks down the practical knowledge required from the various branches of applied science-electrical and mechanical engineering, analog electronics, mechanics, control theory, digital electronics, embedded computing, and firmware design-into a cohesive and usable framework. Today, DC servos are working around the world in countless applications-CD players, ink-jet printers, robots, machining centers, vending machines, eyeglass manufacturing machines, home appliances, and automotive seat positioners, just to name a few. This book balances coverage of theoretical and practical aspects of application and design of DC servomechanisms. It also provides detailed coverage of feedback transducers, particularly the application of optical encoders to real systems. It covers how to use the MATLAB (R) Control System Toolbox specifically for servo design, to make the design process faster and more interactive. It also presents two complete, bench-tested reference designs that can be duplicated using readily available parts, so you can build your own servo and see it in action. Author Stephen M. Tobin is an expert in motion control and electro-optical instrumentation and a respected consultant in the medical device and manufacturing automation communities. In order to instill confidence in the engineers, scientists, students, and hobbyists designing the ever more complex machines of the 21st century, Tobin guides the reader on a short journey through "servo school," imparting his lifelong passion for motion control along the way.

This text provides an introduction to the important physics underpinning current technologies, highlighting key concepts in areas that include linear and rotational motion, energy, work, power, heat, temperature, fluids, waves, and magnetism. This revision reflects the latest technology advances, from smart phones to the Internet of Things, and all kinds of sensors. The author also provides more modern worked examples with useful appendices and laboratories for hands-on practice. There are also two brand new chapters covering sensors as well as electric fields and electromagnetic radiation as applied to current technologies.

The recent explosion in the use of analytical chemistry, particularly in the biological sciences, has led to a need for fast, reliable and highly sensitive tools able to handle small sample sizes. This book illustrates how microfluidics and lab-on-a-chip devices can satisfy the growing need for miniaturized and enhanced analysis. They lend themselves well to mass spectrometric detection as they use samples in the low microlitre range and are handled on a chip. Miniaturization and Mass Spectrometry focuses on one particular technique, mass spectrometry, whose popularity has increased dramatically in the last two decades with the increase in use of biological analysis and the development of two "soft" ionization techniques, ESI and MALDI. These enable the analysis of large but fragile biological molecules such as DNA, proteins and oligosaccharides. The book starts with an introduction to the coupling of microfluidics to mass spectrometry techniques. It then goes on demonstrate the advantages of such a coupling: the MS analysis benefits from improved sample preparation when performed on a chip while MS yields more information on the sample handled on the chip compared to conventional optical detection. A history on the developments in this field, starting from the off-chip coupling to the on-chip ionization, is also provided. Daniel Figeys, a pioneer in the development of microfluidic systems for MS analysis, describes the early beginnings of this hyphenated analysis technique. Solutions to couple microfluidic systems to the two most popular ionization methods, ESI and MALDI, are presented throughout the chapters. Various examples are given of the application of this microfluidics-MS hyphenated analysis technique to proteomics, metabolomics, organic chemistry and forensics. Coverage is not limited to academic research. The development of commercialized systems and their current use for routine biological analysis are also presented. Lastly, a future vision of the integration of the mass spectrometer on the chip is raised, as a last step to yield fully portable systems for on-site analysis.