This volume guides the practitioner in the current management of women with epilepsy, in a comprehensive and scientifically informed manner. Many chapters are devoted to the various aspects of pregnancy management for women with epilepsy, from reducing the risks of medication exposure to breast feeding. All female age groups are discussed and chapters on issues important for adolescents and the mature women are also included. The editors have included internationally recognized experts as contributors, to bring together a body of knowledge unparalleled in previous settings. This book should be a guide to management for women with epilepsy for years to come, due to its solid scientific basis and the comprehensive vision of the contributors.
* Features discussions on issues for women with epilepsy that span from the lab to the clinic
* Encompasses the current state of this evolving topic
* Organized in discreet clinical entities for easy reference with helpful tables and figures"

Epilepsy is one of the most common neurological disorders, and original observations in the field are often the key to diagnosis and successful treatment. Physicians new to the field as well as seasoned practitioners will benefit from more than one hundred case vignettes that explore the universe of epilepsy as it presents in daily practice. Some of these cases challenge long-held views about epilepsy and others bring the reader to the limits of our understanding of epilepsy, both in clinical and basic science. To improve the interface of clinical and basic science in epilepsy, basic scientists comment on the potential mechanisms underlying clinical observations, and clinicians assess the potential impact of recent results of experiments in the laboratory. This book highlights the importance that original observations have in inspiring both new treatments and continued research.
* Presents unique and challenging case vignettes in epilepsy contributed by eminent physicians in the field
* Provides practicing physicians with examples of how baffling cases were handled and solved
* A new section provides a translational perspective, with basic scientists discussing the potential mechanisms underlying original clinical observations, and clinical scientists discussing the clinical implications of experiments in the epilepsy laboratory

As people are living longer on average than ever before, the number of those with dementia will increase. Because many will live a considerable time at home with their diagnosis, we need to know more about the ways people can adapt to and learn to live with dementia in their everyday lives. Lars-Christer Hyden argues in this book that to do so will involve re-imagining what dementia really is and what it can mean to the afflicted and their loved ones. One of the most important everyday opportunities for sharing experiences is the simple act of storytelling. But when someone close to you gradually loses the ability to tell stories and cherish the shared history you have together, this is seen as a threat to the relationship, to the feeling of belonging together, and to the identity of the person diagnosed. Therefore, learning about how people with dementia can participate in storytelling along with their families and friends helps to sustain those relationships and identities. In Entangled Narratives, Hyden not only emphasizes the possibilities that are inherent in collaborative storytelling, but instructs professionals and otherwise healthy relatives to learn how to effectively listen and, ultimately, re-imagine their patients and loved ones as collaborative meaning-makers in their lives.

Neuroethics is concerned with the wide array of ethical, legal and social issues that are raised in research and practice. The field has grown rapidly over the last five years, becoming an active interdisciplinary research area involving a much larger set of academic fields and professions, including law, developmental psychology, neuropsychiatry, and the military.
Neuroethics and Practice helps to define and foster this emerging area at the intersection of neuroethics and clinical neuroscience, which includes neurology, neurosurgery, psychiatry and their pediatric subspecialties, as well as neurorehabiliation, clinical neuropsychology, clinical bioethics, and the myriad other clinical specialties (including nursing and geriatrics) in which practitioners grapple with issues of mind and brain. Chatterjee and Farah have brought together leading neuroethicists working in clinically relevant areas to contribute chapters on an intellectually fascinating and clinically important set of neuroethical topics, involving brain enhancements, brain imaging, competence and responsibility, severe brain damage, and consequences of new neurotechnologies. Although this book will be of direct interest to clinicians, as the first edited volume to provide an overall comprehensive perspective on neurethics across disciplines, it is also a unique and useful resource for a wide range of other scholars and students interested in ethics and neuroscience.

This book covers the explosion of new information about the relationship between the brain and its blood supply since the first edition was published in 2009. With new knowledge and its impact on clinical care, neurovascular neuropsychology has become a recognized sub-specialty that has been integrated into health care systems in the US and abroad. The second edition brings to this larger audience the latest word on these matters, with new emphasis on women's issues, relevance to the pediatric population, insights from modern imaging, and advances in medical and surgical treatments such as heart transplantation, cardiovascular transarterial therapies, and noninvasive brain stimulation in connection with neurocognitive outcomes.

This edited reference addresses controversial clinical issues of the psychiatric aspects of epilepsy. The book explores the reasons behind the poor communication between psychiatrists and neurologists and suggests potential remedies to this important problem, and two chapters are devoted to examining whether psychiatrists and neurologists are properly trained to recognize and treat conditions that both disciplines commonly encounter in clinical practice. Identification of the causes behind the high rate of comorbidity between epilepsy and mood, anxiety, psychotic and attention deficit disorders is given high priority in the volume, and a specific review of the evidence of common pathogenic mechanisms that may be operant in epilepsy and these psychiatric disorders is included. Recently identified bidirectional relationship between mood disorders and epilepsy and its implication in the course and response to treatment of the seizure disorder are also explored. Several chapters are devoted to rectify common misunderstandings of the use of psychotropic drugs in patients with epilepsy, including the use of antidepressant and central nervous system stimulants. Finally, one chapter explores the possibility of organic causes of psychogenic non-epileptic seizures.
* Compiles into one source the important controversial issues of the psychiatric aspects of epilepsy, which have significant implications in clinical practice
* Authors are internationally recognized authorities in the field of psychiatric aspects of epilepsy

In 1997, Vagus Nerve Stimulation (VNS) therapy (Cyberonics, Houston, Texas) was approved by the United States Food and Drug Administration for the treatment of epilepsy refractory to antiepileptic medications. In 2005, VNS received FDA approval for treatment-resistant depression refractory to antidepressants, and Cyberonics recently received FDA approval for the clinical study of VNS for rapid cycling bipolar depression. Many researchers continue to investigate the anxiolytic effects of VNS in human and non-human animal models. The author presents a study of VNS effects on anxiety and the capacity of atropine methyl nitrate to attenuate these effects. The results indicate that VNS decreases anxiety in the laboratory animals tested. These findings provide evidence to support the testing and subsequent use of VNS therapy for the treatment of clinical anxiety in humans. Because many therapies that are effective in the treatment of depression effectively treat anxiety, VNS therapy should be effective and approvable for clinical anxiety. This book can serve as a research tool, training mechanism, or surgical guide to the implantation of the vagus nerve stimulating electrode in the laboratory rat. Hopefully, this resource provides information that facilitates FDA approval of VNS for treatment-resistant anxiety, a chronic, devastating and often debilitating illness.

Dysimmune Neuropathies provides readers with detailed, basic information that will enable users to recognize and differentiate each neuropathy to adequately guide an investigation and create a treatment plan. An overview of recent progress, avenues for future research, and the desired benefits are also covered. The book highlights the many developments in the field that have occurred in terms of pathophysiological mechanisms, particularly immunological, that have direct implications on treatment strategies. This book is a great reference for trainees, clinicians and researchers specializing in neurology, neuromuscular diseases and neurophysiology.

Alzheimer's is a devastating disease, robbing its victims of so much of themselves before the end. For caregivers facing this disease, a diagnosis of Alzheimer's disease can sound like the ultimate tragedy, the disease that will rob us of our loved one by inches. It doesn't have to be. While Alzheimer's and related dementias are serious and not easily understood diseases, a new guide can help families negotiate the difficult scientific, emotional, and practical issues of dealing with the disease. In a moving and easy to read format, Dr. Steinberg has laid out a true caregiver's guide to dealing with Alzheimer's disease, from the first signs to the final stages. Incorporating science, real-life case studies from his practice and from his extensive experience as a nationally recognized seminar speaker, as well as from his personal journey coping with his mother's illness, Dr. Steinberg leads the reader through a learning and healing process. In a candid and personal sharing of his experience, Dr. Steinberg helps the reader clearly understand what to expect, when to ask for help, how to cope with the changes and the inevitable pressures within the family, and how to continue to love as a loved one's disease threatens family stability and well-being. With his profound knowledge of the disease, its treatment and manifestations, and his great love and tenderness as the son of an Alzheimer's patient, Dr. Steinberg has created a truly memorable work.

Ethical Dimensions of Commercial and DIY Neurotechnologies Volume Three, the latest release in the Developments in Neuroethics and Bioethics series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding neuroethics and bioethics. Each chapter is written by an international board of authors.

ABOUT THE BOOK: It seemed nothing Tracy did for her son would work-testing, counseling, medication, therapy-and violent meltdowns were a daily occurrence. She agonized over What is next? What is to become of my beautiful son? Tracy's struggles were long and hard, but with a mother's determination, a supportive family, and God's love and intervention, she found strength, endurance, and unexpected open doors. To the Land of the Lost is a mom's gripping, true story account of the trials faced while parenting a child who has Asperger's syndrome. The story is gut wrenching and heartbreaking, while at the same time loving, uplifting, encouraging, and inspirational. To the Land of the Lost is a must read for any parent, caregiver, teacher, or friend of someone living with an autism spectrum disorder. **** ABOUT THE AUTHOR: Tracy M. Maguire lives in Dublin, Ireland, with her three children: Graham, Sophie, and James. Her eldest son, Graham, now almost 19 years old, has Asperger's syndrome. Tracy is passionate about encouraging parents who are raising a child with Asperger's and giving them hope in what can often feel like a hopeless situation.

Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions.

The purpose of this book is to educate readers regarding the efficacy of cognitive rehabilitation across a variety of neurological conditions, with specific emphasis on rehabilitation-related change detectable via neuroimaging. For ease of reference, this information is divided into separate chapters by neurological condition, since the nature of cognitive impairment and mechanism of rehabilitation may differ across populations. Also included are discussions of the use of neuroimaging in cognitive rehabilitation trials, rigorous design of cognitive rehabilitation trials to have greater scientific impact (e.g., obtaining Class I evidence), and future directions for the field. As such, the book is designed to be useful to both clinicians and researchers involved in the rehabilitation of such conditions so that they can make informed decisions regarding evidence-based treatment to deploy in clinical settings or to further study in research endeavors.

This book explores how theatre and performance can change the way we think about dementia and some of the environments in which dementia care takes place. Drawing on the author's creative practice and other performance projects in the UK, it explores some of the challenges and opportunities of making performance in care homes. Rather than focusing on the transformative potential of the arts, it asks how artists can engage with the different types of relationships that exist in a care community. These include the relationships that residents and staff have with each other as well as relationships with care spaces. Exploring the intersection between participatory performance and the everyday creativity of a care home, it argues that the arts have a cultural role to play in supporting dementia care as a relational practice. Moreover, it celebrates the intrinsic creativity of caregiving and how principles and practices of care work can inform theatre and performance in diverse ways.

International Review of Research in Mental Retardation is an ongoing scholarly look at research into the causes, effects, classification systems, syndromes, etc. of mental retardation. Contributors come from wide-ranging perspectives, including genetics, psychology, education, and other health and behavioral sciences.
Volume 35 of the series offers chapters on theory and research, social cognition and social competence in children with Down Sydrome, the Flynn Effect and the role of IQ, remaining open to quantitative, qualitative and mixed-method designs, active support, child abuse, and the role of siblings of children with mental retardation.
The wide range of topics covered in these chapters make Volume 35 of the International Review of Research in Mental Retardation a particularly valuable resource for academic researchers in developmental and cognitive psychology, as well as those in neuropsychology.
*Provides the most recent scholarly research in the study of mental retardation
*A vast range of perspectives is offered, and many topics are covered
*An excellent resource for academic researchers

This book provides an essential overview of the broad range of functional brain imaging techniques, as well as neuroscientific methods suitable for various scientific tasks in fundamental and clinical neuroscience. It also shares information on novel methods in computational neuroscience, mathematical algorithms, image processing, and applications to neuroscience. The mammalian brain is a huge and complex network that consists of billions of neural and glial cells. Decoding how information is represented and processed by this neural network requires the ability to monitor the dynamics of large numbers of neurons at high temporal and spatial resolution over a large part of the brain. Functional brain optical imaging has seen more than thirty years of intensive development. Current light-using methods provide good sensitivity to functional changes through intrinsic contrast and are rapidly exploiting the growing availability of exogenous fluorescence probes. In addition, various types of functional brain optical imaging are now being used to reveal the brain's microanatomy and physiology.

This book comprehensively examines chemotherapy-induced peripheral neuropathy (CIPN), a common dose-limiting condition that negatively affects both the quality of life of cancer patients and disease outcomes. CIPN remains a challenging area for both clinical care and research, as there are multiple unresolved issues. Written by leading international experts, the book discusses the natural history of CIPN, the latest predictors of toxicity, instruments for evaluating symptoms, and prevention/therapeutic strategies, as well as patients' experiences of this common clinical syndrome. Lastly it highlights avenues for future research to enhance our understanding of CIPN. Providing essential information on the management of CIPN and the latest research in the field, this book is a valuable resource for researchers and healthcare providers working with patients with various malignant diseases.

State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer s disease, Parkinson s disease, stroke, viral encephalitides and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters."

Brain-Inspired IT III is the third volume of the Brain-Inspired IT series intended for researchers and students who are involved or interested in the brain sciences, technology, and engineering. Brain-Inspired IT III includes 4 invited papers, 7 COE papers, 57 selected papers from the Third International Symposium BrainIT 2006, which was held in Kitakyushu, Japan, on September 27-29, 2006. The last two International symposiums BrainIT 2004 and 2005 were great success, and provided the participants with good opportunities to exchange valuable information and various ideas from multidisciplinary research area. We made a survey of the current state-of-the-art and explored the possibility to establish new research fields in the Brain-Inspired Information Technology. The first 4 invited papers are contributed by outstanding researchers in the area, Dr. M. Kawato (ATR Computational Neuroscience Laboratories), Prof. Ryohei Kanzaki (The University of Tokyo), Prof. Asla Pitkanen (University of Kuopio), Prof. Helge Ritter (Bielefeld University), who were presented in the special and invited sessions of BrainIT2006 to discuss how the brain processes the information and how we apply the processing to technology. Technical papers cover vision system, other sensory systems, cognition and languages, learning and memory, behavior and emotion, motor controls, dynamics, neural computation, neural networks, and brain-inspired intelligent machines. Hopefully this Brain-Inspired IT series will be a key milestone for researchers and students to pioneer the new field Brain-Inspired Information Technology.

This book provides readers with the information they need to better understand Alzheimer's disease. Written in easy-to-understand language, it is aimed at those who may have a parent, grandparent, or other loved one struggling with this condition. Alzheimer's disease is a neurodegenerative disorder that causes problems with thinking, memory, and behavior. Such symptoms as memory loss usually develop slowly but get worse over time, eventually becoming severe enough to interfere with daily activities and bodily functions. What You Need to Know about Alzheimer's Disease is part of Greenwood's Inside Diseases and Disorders series. This series profiles a variety of physical and psychological conditions, distilling and consolidating vast collections of scientific knowledge into concise, readable volumes. A list of "Top 10" essential questions begins each book, providing quick-access answers to readers' most pressing concerns. The text follows a standardized, easily navigable structure, with each chapter exploring a particular facet of the topic. In addition to covering such basics as causes, signs and symptoms, diagnosis, and treatment options, books in this series delve into issues that are less commonly addressed but still critically important, such as effects on loved ones and caregivers. Case illustrations highlight key themes discussed in the book and are accompanied by insightful analyses and recommendations. Content approaches the subject in a holistic manner, covering often-overlooked areas, such as societal perceptions and impact on family and friends An Essential Questions section provides quick-access answers to the questions that readers are most likely to have Case Illustrations provide relatable, real-world examples of concepts discussed in the text An annotated Directory of Resources points readers toward useful books, organizations, and websites, acting as a gateway to further research