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Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology

The Autism-Friendly Cookbook (Paperback): Lydia Wilkins The Autism-Friendly Cookbook (Paperback)
Lydia Wilkins
R652 R492 Discovery Miles 4 920 Save R160 (25%) Ships in 12 - 17 working days

The Autism-Friendly Cookbook was created by journalist Lydia Wilkins for autistic adults and teens to turn to when cooking for friends, lacking inspiration, or on those low-energy days. With recipes to suit any occasion, the book is written in clear, jargon-free language which makes 'the obvious' obvious. Recipes are categorised by meal with additional guidance on the level of energy needed to tackle them, with options for low-energy or meltdown days, or days when you're able to take on a new challenge. They contain adaptations and options to suit different dietary needs including vegetarian, vegan, gluten-free and dairy-free, and additional modifications for those who are sensory seekers, sensory avoiders or who want to expand their repertoire in the kitchen. With contributions from individuals within the autistic community and options for quick meals, special occasions and more. With autistic people at its heart, the book also contains helpful tips and advice for parents and teachers looking to find out more.

Our House is on Fire - Scenes of a Family and a Planet in Crisis (Hardcover): Malena Ernman, Greta Thunberg, Beata Ernman,... Our House is on Fire - Scenes of a Family and a Planet in Crisis (Hardcover)
Malena Ernman, Greta Thunberg, Beata Ernman, Svante Thunberg 1
R521 R425 Discovery Miles 4 250 Save R96 (18%) Ships in 9 - 15 working days

The profoundly moving story of how love, courage and determination brought Greta Thunberg's family back from the brink 'Urgent, lucid, courageous ... a must-read message of hope ... It is a glimpse of a saner world' David Mitchell, Guardian This is the story of a happy family whose life suddenly fell apart, never to be the same again. Of two devoted parents plunged into a waking nightmare as their eleven-year-old daughter Greta stopped speaking and eating, and her younger sister struggled to cope. They desperately searched for answers, and began to see how their children's suffering reached far beyond medical diagnoses. This crisis was not theirs alone: they were burned-out people on a burned-out planet. And so they decided to act. Our House is on Fire shows how, amid forces that tried to silence them, one family found ways to strengthen, heal, and gain courage from the love they had for each other - and for the living world. It is a parable of hope and determination in an emergency that affects us all.

Cognitive Retraining Using Microcomputers (Paperback): Veronica A. Bradley, John L. Welch, Clive E. Skilbeck Cognitive Retraining Using Microcomputers (Paperback)
Veronica A. Bradley, John L. Welch, Clive E. Skilbeck
R1,039 Discovery Miles 10 390 Ships in 12 - 17 working days

Originally published in 1993, the previous decade had seen considerable development in the field of neuropsychological rehabilitation following brain damage, and the use of computerized methods attracted attention and stimulated controversy. This practically-oriented text reviews representative examples from the literature at the time relating to the training of cognitive systems with the emphasis on studies describing the use of computerized methods. The topic is discussed in context and the contents include sections on cognitive change in neurological disorders, assessment techniques, the interaction between cognition and behaviour and the advantages and disadvantages of the use of microcomputers. The authors describe the evaluation of a computerized cognitive retraining programme run at the Regional Neurological Centre in Newcastle-upon-Tyne and draw on their experience of running such programmes to give practical guidance to those wishing to set up cognitive retraining programmes.

Cognitive Approaches in Neuropsychological Rehabilitation (Paperback): Xavier Seron, Gerard Deloche Cognitive Approaches in Neuropsychological Rehabilitation (Paperback)
Xavier Seron, Gerard Deloche
R1,034 Discovery Miles 10 340 Ships in 12 - 17 working days

Originally published in 1989, presenting a new perspective on cognitive therapy in neuropsychology, these papers examine a cognitively-oriented, single-case methodology in neuropsychological rehabilitation. The recommended strategy is in-depth analysis of the precise nature of the impaired as well as the preserved processing components in the individual patient. The objective is to design a therapeutic course based on individual patient needs that is justified by the theoretical interpretation of the location of the deficit in his or her cognitive architecture.

A Spectrum of Solutions for Clients with Autism - Treatment for Adolescents and Adults (Hardcover): Rachel Bedard, Lorna Hecker A Spectrum of Solutions for Clients with Autism - Treatment for Adolescents and Adults (Hardcover)
Rachel Bedard, Lorna Hecker
R3,926 Discovery Miles 39 260 Ships in 12 - 17 working days

* Gives clinicians who work with ASD clients a book with expertise from various contributing disciplines to give them a treatment resource that can guide their daily work * Pulls together common treatment themes, while recognizing the true "spectrum" that occurs in treatment by offering 3 different voices in each chapter, with experts speaking to effective intervention, but from three different professional points of view on the same clinical topic. * Offers insights from well-known adults on the spectrum (Dr. Temple Grandin, Michael John Carley, and others) who can provide insight about what the ASD population needs from professionals

New Developments in Dementia Prevention Research - State of the Art and Future Possibilities (Paperback): Kate Irving, Eef... New Developments in Dementia Prevention Research - State of the Art and Future Possibilities (Paperback)
Kate Irving, Eef Hogervorst, Deborah Oliveira, Miia Kivipelto
R1,266 Discovery Miles 12 660 Ships in 12 - 17 working days

New Developments in Dementia Prevention Research addresses a dearth of knowledge about dementia prevention and shows the importance of considering the broader social impact of certain risk factors, including the role we each play in our own cognitive health throughout the lifespan. The book draws on primary and secondary research in order to investigate the relationship between modifiable factors, including vascular and psychosocial risks, that may affect the incidence of dementia. Bringing together world-leading expertise from applied science, medicine, psychology, health promotion, epidemiology, health economics, social policy and primary care, the book compares and contrasts scientific and service developments across a range of settings. Each chapter presents these themes in a way that will ensure best practice and further research in the field of dementia prevention is disseminated successfully throughout the world. Perhaps most importantly, chapters also question what type of social responsibility we are prepared to embrace in order to address the challenges inherent in dementia prevalence. New Developments in Dementia Prevention Research includes contributions from leading authorities in brain health and dementia prevention and provides an essential contribution to the discourse on dementia prevention. It will be of great interest to academics, researchers and postgraduate students engaged in the study of the psychological and social aspects of aging and dementia.

Digital Technologies in Movement Disorders, Volume 5 (Hardcover): Alvaro Sanchez Ferro, Mariana Hernandez Gonzalez-Monje Digital Technologies in Movement Disorders, Volume 5 (Hardcover)
Alvaro Sanchez Ferro, Mariana Hernandez Gonzalez-Monje
R5,699 Discovery Miles 56 990 Ships in 12 - 17 working days

Digital Technologies in Movement Disorders, Volume Five updates on the latest advances in new technologies for the care of common conditions, including Parkinson’s disease and other diseases. The book has been organized in four differentiated sections with chapters that cover an Introduction, key concepts, and overview of digital solutions, Applications of AI in MD, Digital Biomarkers in MD, Sensors basic concepts for the MD specialist, Wearable systems in MD, Quantitative gait analysis, The challenges and opportunities of remote evaluation in MD, Telemedicine in MD, ePROs, eCOA and other digital health solutions, HIFU, Telerrehabilition and other therapeutical applications of technology, and more.

Treating Nonepileptic Seizures - Therapist Guide (Paperback): W. Curt LaFrance Jr, Jeffrey Peter Wincze Treating Nonepileptic Seizures - Therapist Guide (Paperback)
W. Curt LaFrance Jr, Jeffrey Peter Wincze
R2,384 Discovery Miles 23 840 Ships in 10 - 15 working days

The primary aim of Treating Nonepileptic Seizures: Therapist Guide is to equip physicians, psychologists, therapists, nurses, and other practitioners with a validated, step-by-step treatment for psychogenic nonepileptic seizures (NES) that can improve the lives of patients with this disabling disorder. Patients with NES frequently present in neurology, psychiatry, psychology, and emergency departments. The disorder has been documented in the medical literature for centuries, and much is known about the phenomenology, seizure characteristics, psychiatric comorbidities, neuropsychological testing, and psychosocial aspects in NES. However, until recently, much less was known about the effective treatments of patients with psychogenic NES. This intervention provides guidance for clinicians in treating patients with NES and is designed to be used in conjunction with the patient workbook, Taking Control of Your Seizures. Session by session, the Workbook facilitates communication between treatment providers and individual patients with seizures. The authors' clinical experience with epilepsy and NES and research in developing the treatment approach for seizures directly informed the treatment model described. Many patients treated with the intervention have demonstrated improvements in seizures, symptoms, and quality of life.

Chronic PAIN - Assessment, Diagnosis, and Management (Paperback): Michael Margoles, Richard S. Weiner Chronic PAIN - Assessment, Diagnosis, and Management (Paperback)
Michael Margoles, Richard S. Weiner
R1,809 Discovery Miles 18 090 Ships in 12 - 17 working days

Chronic pain affects every aspect of life-physical well-being, mood, stamina, and feelings of self worth and self respect. This book focuses on conquering pain and its related problems through proper management. It offers numerous tools and concepts with which to attack chronic pain and win the battle that more than 35 million people in the U.S. alone fight every day. Virtually all specialists in the health care field must be concerned with pain management-this complete reference offers them strategies for helping their patients, and for patients to help themselves. Chronic Pain: Assessment, Diagnosis, and Management presents a variety of therapies for combating chronic pain, including: Applying external therapy Changing the way patients perceive pain through psychotherapy or other cognitive means Physical therapy and exercises Over-the-counter or prescription medicines to relieve pain, stress, and insomnia caused by discomfort Surgical options The book also contains never before published information on how to prescribe and administer opioids and opioid-containing analgesics for chronic, intractable, and non-malignant pain patients. There is hope for those suffering from chronic pain. This book outlines commonly overlooked problems that, if properly addressed, can make the difference between a patient recovering or effectively managing their pain-or not. Chronic Pain: Assessment, Diagnosis, and Management is full of practical advice and options for anyone suffering from chronic pain and for the doctors who treat them.

A Brief History of Intelligence - Why the Evolution of the Brain Holds the Key to the Future of Ai (Paperback): Max Bennett A Brief History of Intelligence - Why the Evolution of the Brain Holds the Key to the Future of Ai (Paperback)
Max Bennett
R430 Discovery Miles 4 300 Ships in 12 - 17 working days

A Brief History of Brains bridges the gap between AI and neuroscience by telling the evolutionary story of how the brain came to be. The entirety of the human brain’s 4-billion-year story can be summarised as the culmination of five evolutionary breakthroughs, starting from the very first brains, all the way to the modern human brains. Each breakthrough emerged from new sets of brain modifications, and equipped animals with a new suite of intellectual faculties. These five breakthroughs are the organising map to this book, and they make up our itinerary for our adventure back in time. Each breakthrough also has fascinating corollaries to breakthroughs in AI. Indeed, there will be plenty of such surprises along the way. For instance: the innovation that enabled AI to beat humans in the game of Go – temporal difference reinforcement learning – was an innovation discovered by our fish ancestors over 500 million years ago. The solutions to many of the current mysteries in AI – such as ‘common sense’ – can be found in the tiny brain of a mouse. Where do emotions come from? Research suggests that they may have arisen simply as a solution to navigation in ancient worm brains. Unravelling this evolutionary story will reveal the hidden features of human intelligence and with them, just how your mind came to be.

The Developing Brain and its Connections (Hardcover): Lynne M. Bianchi The Developing Brain and its Connections (Hardcover)
Lynne M. Bianchi
R5,845 Discovery Miles 58 450 Ships in 12 - 17 working days

Written by a single author in a clear and consistent writing style, presents a logical and easy to follow discussion about each phase of neural development Presents an accessible approach to developmental neurobiology for students who do not have an extensive background in neuroscience or cell and molecular biology Clear, informative, and easy-to-follow illustrations support the concepts presented in the text Highlights neurodevelopmental and neurodegenerative disorders where relevant and therapeutic approaches to neurological diseases

Autism Causes Vaccines - Stories of Neurodiverse Inventors and Discoveries (Paperback): Joe Biel Autism Causes Vaccines - Stories of Neurodiverse Inventors and Discoveries (Paperback)
Joe Biel
R175 R143 Discovery Miles 1 430 Save R32 (18%) Ships in 10 - 15 working days
The Human Brain during the First Trimester 21- to 23-mm Crown-Rump Lengths - Atlas of Human Central Nervous System Development,... The Human Brain during the First Trimester 21- to 23-mm Crown-Rump Lengths - Atlas of Human Central Nervous System Development, Volume 4 (Hardcover)
Shirley A. Bayer, Joseph Altman
R3,464 Discovery Miles 34 640 Ships in 12 - 17 working days

1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal neorological development 3) Appeals to neuroanatomists, developmental biologists and clinical practioners. 4) Persistent relevantce - brain development is not going to change.

Reinforcement Sensitivity Theory - A Metatheory for Biosocial Criminology (Paperback): Anthony Walsh Reinforcement Sensitivity Theory - A Metatheory for Biosocial Criminology (Paperback)
Anthony Walsh
R1,240 Discovery Miles 12 400 Ships in 12 - 17 working days

Some of the brightest minds in criminology who were nurtured on the strictly environmentalist paradigm of the 20th century have declared that biosocial criminology is the paradigm for the 21st century. This book attempts to unite this ever-growing field with the premier neurobiological theory of personality, otherwise known as reinforcement sensitivity theory (RST). Anthony Walsh places the highly variable number of biosocial approaches under a single theoretical umbrella, whilst providing a unique integrative framework. As the leading neurobiological theory of personality and behavior in psychology today, RST focuses around the age-old question of how naturally selfish social animals can achieve their wants and needs without alienating others in their social groups. RST posits that evolution has built into humans three interacting systems: the behavioral approach system; the behavioral inhibition system; and the fight/flight/freeze system. RST identifies the neurobiological and genetic functions underlying each system and has found a cascade of supporting evidence. Throwing new light on many areas of concern to criminologists, such as psychopathy, violence, ADHD, and schizophrenia, this book will be of interest to scholars and upper-level students in the field. Additional features such as Focus Boxes and diagrams delve into measurement techniques and brain areas.

The Human Brain Colouring Book (Paperback, 1st ed): Marion C. Diamond, Arnold B. Scheibel, L.M. Elson The Human Brain Colouring Book (Paperback, 1st ed)
Marion C. Diamond, Arnold B. Scheibel, L.M. Elson
R544 R414 Discovery Miles 4 140 Save R130 (24%) Ships in 12 - 17 working days

Developed by internationally renowned neurosurgeons, this unique book is designed for students of psychology and the biological sciences, and medical, dental, and nursing students.

Nature's Gift to Neuroscience - A Tribute to Sydney Brenner and John Sulston (Hardcover): Chun-Fang Wu, Joy Alcedo Nature's Gift to Neuroscience - A Tribute to Sydney Brenner and John Sulston (Hardcover)
Chun-Fang Wu, Joy Alcedo
R3,941 Discovery Miles 39 410 Ships in 12 - 17 working days

In the 1960s, Sydney Brenner proposed to use the nematode worm Caenorhabditis elegans to discover the control mechanisms of animal development and to reveal how a small number of neurons generate different behaviours, giving birth to a vibrant community that uses this animal model for their studies. Brenner was aided in his aim by John Sulston, who mapped the C. elegans cell lineages - from a single cell to the multicellular adult - which transformed the field of developmental biology. As a tribute to these two men, this book captures the perspectives of some of the early pioneers of the worm community, from Martin Chalfie, Robert Waterston and Donald Moerman to Catherine Rankin, Antony Stretton and John White. It also includes contributions from subsequent generations of the community, who explore the development and function of the C. elegans nervous system. This book features how this animal has become one of the best models for elucidating the biology of different sensory modalities and their complex behavioural outputs, or how this animal's survival strategies have contributed to our understanding of ageing and neurodegeneration. Thus, this volume documents the development of the C. elegans neuroscience field, from infancy to maturity. The chapters in this book were originally published as a special issue of the Journal of Neurogenetics.

Neurocinema-The Sequel - A History of Neurology on Screen (Hardcover): Eelco F.M. Wijdicks Neurocinema-The Sequel - A History of Neurology on Screen (Hardcover)
Eelco F.M. Wijdicks
R3,348 Discovery Miles 33 480 Ships in 12 - 17 working days

1.Compares the real history of neurology with the "reel" history 2. Includes discussion and interpretation of 180 films with neurologic topics 3.Features defining photographs from many famous films 4.Features original material from the Silent Film era

Autism Parent to Parent - Sanity-Saving Advice for Every Parent with a Child on the Autism Spectrum (Paperback): Shannon Penrod Autism Parent to Parent - Sanity-Saving Advice for Every Parent with a Child on the Autism Spectrum (Paperback)
Shannon Penrod
R528 R440 Discovery Miles 4 400 Save R88 (17%) Ships in 10 - 15 working days

Your child has been diagnosed with Autism Spectrum Disorder and you are feeling overwhelmed and alone. Suddenly you need to become an expert in treatment, diet, language development, social skills, special education law, insurance and a million other things! What you'd really like to know is how to deal with Aunt Martha's questions at the family reunion! Autism: Parent to Parent is your guide to all of this and more. Veteran parent Shannon Penrod hosts Autism Live, the #1 rated Autism Podcast worldwide, now she is giving you all her best resources, strategies, tips and information to help you and your child survive and thrive. Autism: Parent to Parent covers everything you need to know such as: What do you say to pushy relatives? How do you get the best treatment options? How do you deal with school? Most importantly, how do you deal with all the emotions that come with day-to-day life? Ms. Penrod covers all a parent of an individual with ASD needs to know, with honesty, humor and humility while empowering you to rise to meet all the challenges and triumphs on your journey.

Understanding ADHD - A Guide to Symptoms, Management and Treatment (Hardcover): Anna Maria Re, Agnese Capodieci Understanding ADHD - A Guide to Symptoms, Management and Treatment (Hardcover)
Anna Maria Re, Agnese Capodieci
R4,054 Discovery Miles 40 540 Ships in 12 - 17 working days

This essential guide provides accessible, concise, evidence-based guidelines on Atttention Deficit Hyperactivity Disorder (ADHD), offering a deeper scientific understanding of the condition and its consequences. It offers ideas and insights for managing the condition in daily family life and promoting the most effective self-regulation strategies for children and adolescents, allowing parents to better understand the origins of their child's behaviour and avoid potential negative consequences. In this straightforward text, Capodieci and Re set out the basic theories on ADHD and cover key topics including parent-child relationships, helping children understand their condition, friendships with peers, comorbidities, classroom strategies, and how families and professionals can best work together. Taking into account the most recent updates to the DSM-5 definition of ADHD, the authors emphasise the importance of a multifocal approach to the treatment of ADHD, involving the child's teachers, parents and peers, to better develop family and peer relationships. They offer strategies for the classroom, for good sleep and for healthy eating and physical activity, and support for any other learning, language, movement and emotional problems an ADHD child might have. Understanding ADHD will be essential reading for parents of children with ADHD, as well as health, education and social care professionals involved in the field.

Unrepressed Unconscious, Implicit Memory, and Clinical Work (Hardcover): Giuseppe Craparo, Clara Mucci Unrepressed Unconscious, Implicit Memory, and Clinical Work (Hardcover)
Giuseppe Craparo, Clara Mucci
R3,840 Discovery Miles 38 400 Ships in 9 - 15 working days

Unrepressed Unconscious, Implicit Memory, and Clinical Work analyses the psychological and neurobiological characteristics of what nowadays goes under the name of "unrepressed unconscious", as opposed to Freud's earlier version of a kind of "repressed unconscious" encountered and described initially in his work with hysterical patients. Pioneering Italian psychoanalyst and neuroscientist Mauro Mancia has distinguished this seminal Freudian concept from an earlier version of the unconscious (preverbal and pre-symbolic) that he terms "unrepressed", and which he describes as "having its foundations in the sensory experiences the infant has with his mother (including hearing her voice, which recalls prosodic experiences in the womb). In connection with this description of two different kinds of unconscious, a 'double' system of memory has been identified: if a traumatic event or series of events takes place when the nervous system is not ready to encode them linguistically and register them within the declarative memory system, they leave a trace within the implicit memory and particularly within the right brain, which both Mancia and Schore see as the seat of implicit memory.

The Living Well with Dementia Course - A Workbook for Facilitators (Paperback): Richard Cheston, Ann Marshall The Living Well with Dementia Course - A Workbook for Facilitators (Paperback)
Richard Cheston, Ann Marshall
R1,092 Discovery Miles 10 920 Ships in 9 - 15 working days

The Living Well with Dementia Course: A Workbook for Facilitators will be an indispensable guide to providing support to people after they have received a dementia diagnosis. The workbook provides facilitators with a realistic but positive approach to helping people with dementia understand and adjust to their condition, helping them to live as well as possible. This workbook outlines the Living Well with Dementia course, a post-diagnostic course for people who have recently received a diagnosis of dementia. Its session-by-session structure, along with e-resources including handouts for course participants, will help facilitators provide a realistic but positive approach to support after a diagnosis. Aimed at facilitators, and drawing on the authors' many years of clinical and research experience, The Living Well with Dementia Course workbook will be of great assistance to healthcare professionals and support workers in many different settings, including specialist NHS dementia services, primary care services and the voluntary and community sector.

Concussive Brain Trauma - Neurobehavioral Impairment and Maladaptation (Paperback, 2nd edition): Rolland S. Parker Concussive Brain Trauma - Neurobehavioral Impairment and Maladaptation (Paperback, 2nd edition)
Rolland S. Parker
R1,858 Discovery Miles 18 580 Ships in 12 - 17 working days

Focusing on a public health problem affecting millions of people of all ages, the second edition of Concussive Brain Trauma: Neurobehavioral Impairment and Maladaptation reflects Dr. Rolland S. Parker's more than 25 years of neuropsychological practice and research in traumatic brain injury and stress, and his prior experience as a clinical psychologist. Unique in its coverage of the personality changes, family dysfunction, and stress that often occur in the wake of concussive brain trauma, this book uses case examples to illustrate persistent and acute alterations of consciousness, as well as cognitive, mood, personality, and social effects of head injury in order to guide appropriate treatment. With six additional chapters, this edition covers: Post-concussive syndrome, biomechanical causes of trauma, and acute and chronic phases of co-morbid brain and somatic injury The physiological basis for behavior and posttraumatic dysregulation of systems Disorders related to pain, sensation, and motor activities Headaches, consciousness, cognition, cerebral personality, and psychodynamic disorders Developmental effects of children's concussive injury Blast injuries characteristic of modern war Unfamiliar signs not included in the usual list of post-concussive symptoms With a firm multi-disciplinary foundation, this book aids the concerned practitioner in rendering a more complete and accurate assessment, recognizing gaps in prior documentation, and conducting a more complete examination to acquire omitted information. It also shows how to achieve the benefit of higher accuracy in assessing disability, planning rehabilitation, and offering compensation. The book stands alone as an in-depth, authoritative guide to closed head injury and traumatic brain injury.

Drug Repositioning - Approaches and Applications for Neurotherapeutics (Paperback): Joe L Dudley, Laura Berliocchi Drug Repositioning - Approaches and Applications for Neurotherapeutics (Paperback)
Joe L Dudley, Laura Berliocchi
R2,148 Discovery Miles 21 480 Ships in 12 - 17 working days

Nervous system diseases represent a major health concern worldwide. Although important financial and professional investment, their etiology and pathophysiology still remain mostly elusive. Moreover, the clinical need of disease-modifying therapies is still unmet. In the last decades, traditional R&D has failed in identifying new effective therapies in many medical areas and drug repositioning has recently emerged as a promising alternative strategy to de novo drug discovery to improve and accelerate therapeutic development. For the first time, Drug Repositioning: Approaches and Applications for Neurotherapeutics reviews history and advances in drug repositioning, with a special focus on therapeutics for nervous system diseases. International experts from Academia, Industry and Non-profit organisations will provide different views on drug repositioning advantages, challenges and specific applications, which will be covered for nervous system diseases including Alzheimer's, Parkinson's, Huntington's diseases, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, ischemic stroke, and psychiatric disorders. This book provides a balanced overview and synthesis of drug repositioning concept, methods and applications for neurotherapeutics. It represents a valuable resource for students, scientists and clinicians working in academic settings, industry and government agencies within the fields of neuroscience, pharmacology, neurology, pharmaceutical sciences, drug discovery and development.

Mapping of Nervous System Diseases via MicroRNAs (Paperback): Christian Barbato, Francesca Ruberti Mapping of Nervous System Diseases via MicroRNAs (Paperback)
Christian Barbato, Francesca Ruberti
R1,654 Discovery Miles 16 540 Ships in 12 - 17 working days

In recent years, understanding of microRNA (miRNA) biogenesis, the molecular mechanisms by which miRNAs regulate gene expression, and the functional roles of miRNAs has expanded. Mapping of Nervous System Diseases via MicroRNAs provides an up-to-date review on the function of miRNA in neurological diseases as well as advancements in technology for therapeutic modulation of miRNA activity. MicroRNAs are small RNA molecules that regulate gene expression post-transcriptionally. A growing body of evidence suggests that miRNAs are dysregulated in several neurological disorders. In addition to reviewing general concepts and novel insights on brain function in relation to miRNA, this book also examines the role of miRNA in: Neurological diseases Neurodegenerative diseases Neuropsychiatric diseases Neurodevelopmental diseases The book also discusses the significance of miRNAs as diagnostic tools, biomarkers, agents, and targets in the detection and treatment of neurological diseases. Each chapter contains material regarding future diagnostic and therapeutic advances. Molecular and cellular neurobiological studies of miRNA-mediated gene silencing in the nervous system have opened new frontiers for the development of new diagnostic tests and genetic therapies for neurological diseases. Covering the full range of relevant concepts and giving a look into present and future possibilities, Mapping of Nervous System Diseases via MicroRNAs is a necessary cutting-edge reference for neurologists, neuropathologists, and researchers and practitioners in a wide range of related fields.

Dementia as Social Experience - Valuing Life and Care (Paperback): Gaynor MacDonald, Jane Mears Dementia as Social Experience - Valuing Life and Care (Paperback)
Gaynor MacDonald, Jane Mears
R1,268 Discovery Miles 12 680 Ships in 12 - 17 working days

A diagnosis of dementia changes the ways people engage with each other - for those living with dementia, as well their families, caregivers, friends, health professionals, neighbours, shopkeepers and the community. Medical understandings, necessary as they are, provide no insights into how we may all live good lives with dementia. This innovative volume brings together an interdisciplinary group of researchers and practitioners to focus on dementia as lived experience. It foregrounds dementia's social, moral, political and economic dimensions, investigating the challenges of reframing the dementia experience for all involved. Part I critiques the stigmas, the negativity, language and fears often associated with a dementia diagnosis, challenging debilitating representations and examining ways to tackle these. Part II examines proactive practices that can support better long-term outcomes for those living with dementia. Part III looks at the relational aspects of dementia care, acknowledging and going beyond the notion of person-centred care. Collectively, these contributions highlight the social and relational change required to enhance life for those with dementia and those who care for them. Engaging in a critical conversation around personhood and social value, this book examines the wider social contexts within which dementia care takes place. It calls for social change, and looks for inspiration to the growing movement for relational care and the caring society. Dementia as Social Experience is important reading for all those people who, in various ways, are living with dementia, as well as for those working in this area as clinicians, researcher and carers.

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