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Books > Science & Mathematics > Science: general issues > Scientific equipment & techniques, laboratory equipment
Replication, the independent confirmation of experimental results and conclusions, is regarded as the "gold standard" in science. This book examines the question of successful or failed replications and demonstrates that that question is not always easy to answer. It presents clear examples of successful replications, the discoveries of the Higgs boson and of gravity waves. Failed replications include early experiments on the Fifth Force, a proposed modification of Newton's Law of universal gravitation, and the measurements of "G," the constant in that law. Other case studies illustrate some of the difficulties and complexities in deciding whether a replication is successful or failed. It also discusses how that question has been answered. These studies include the "discovery" of the pentaquark in the early 2000s and the continuing search for neutrinoless double beta decay. It argues that although successful replication is the goal of scientific experimentation, it is not always easily achieved.
Photoemission (also known as photoelectron) spectroscopy refers to the process in which an electron is removed from a specimen after the atomic absorption of a photon. The first evidence of this phenomenon dates back to 1887 but it was not until 1905 that Einstein offered an explanation of this effect, which is now referred to as ""the photoelectric effect"". Quantitative Core Level Photoelectron Spectroscopy: A Primer tackles the pragmatic aspects of the photoemission process with the aim of introducing the reader to the concepts and instrumentation that emerge from an experimental approach. The basic elements implemented for the technique are discussed and the geometry of the instrumentation is explained. The book covers each of the features that have been observed in the X-ray photoemission spectra and provides the tools necessary for their understanding and correct identification. Charging effects are covered in the penultimate chapter with the final chapter bringing closure to the basic uses of the X-ray photoemission process, as well as guiding the reader through some of the most popular applications used in current research.
Limited resources and other factors pose major challenges for engineering, technology, and science educators ability to provide adequate laboratory experience for students. An Internet accessible remote laboratory, which is an arrangement that allows laboratory equipment to be controlled remotely, addresses these difficulties and allows more efficient laboratory management. Internet Accessible Remote Laboratories: Scalable E-Learning Tools for Engineering and Science Disciplines collects current developments in the multidisciplinary creation of Internet accessible remote laboratories. This book offers perspectives on teaching with online laboratories, pedagogical design, system architectures for remote laboratories, future trends, and policy issues in the use of remote laboratories. It is useful resource for graduate and undergraduate students in electrical and computer engineering and computer science programs, as well as researchers who are interested in learning more about the current status of the field, as well as various approaches to remote laboratory design.
Spark scientific curiosity from a young age with this six-level course through an enquiry-based approach and active learning. Collins International Primary Science fully meets the requirements of the Cambridge Primary Science Curriculum Framework from 2020 and has been carefully developed for a range of international contexts. The course is organised into four main strands: Biology, Chemistry, Physics and Earth and Space and the skills detailed under the 'Thinking and Working Scientifically' strand are introduced and taught in the context of those areas. For each Workbook at Stages 1 to 6, we offer: A write-in Workbook linked to the Student's Book New language development activities help build science vocabulary Earth and Space content covers the new curriculum framework Thinking and Working Scientifically deepens and enhances the delivery of Science skills Actively learn through practical activities that don't require specialist equipment or labs Scaffolding allows students of varying abilities to work with common content and meet learning objectives Supports Cambridge Global Perspectives (TM) with activities that develop and practise key skills Provides learner support as part of a set of resources for the Cambridge Primary Science curriculum framework (0097) from 2020 This series is endorsed by Cambridge Assessment International Education to support the new curriculum framework 0097 from 2020.
Spark scientific curiosity from a young age with this six-level course through an enquiry-based approach and active learning. Collins International Primary Science fully meets the requirements of the Cambridge Primary Science Curriculum Framework from 2020 and has been carefully developed for a range of international contexts. The course is organised into four main strands: Biology, Chemistry, Physics and Earth and Space and the skills detailed under the 'Thinking and Working Scientifically' strand are introduced and taught in the context of those areas. For each Student's Book at Stages 1 to 6, we offer: A full colour and highly illustrated Student's Book Photo-rich spreads show that science is 'real' and puts it into context Earth and Space content covers the new curriculum framework Thinking and Working Scientifically deepens and enhances the delivery of Science skills Actively learn through practical activities that don't require specialist equipment or labs Scaffolding allows students of varying abilities to work with common content and meet learning objectives Supports Cambridge Global Perspectives (TM) with activities that develop and practise key skills Provides learner support as part of a set of resources for the Cambridge Primary Science curriculum framework (0097) from 2020 This series is endorsed by Cambridge Assessment International Education to support the new curriculum framework 0097 from 2020.
The first edition of this classic book has become the authoritative reference for physicists desiring to master the finer points of statistical data analysis. This second edition contains all the important material of the first, much of it unavailable from any other sources. In addition, many chapters have been updated with considerable new material, especially in areas concerning the theory and practice of confidence intervals, including the important Feldman?Cousins method. Both frequentist and Bayesian methodologies are presented, with a strong emphasis on techniques useful to physicists and other scientists in the interpretation of experimental data and comparison with scientific theories. This is a valuable textbook for advanced graduate students in the physical sciences as well as a reference for active researchers.
Annual Reports in Computational Chemistry is a new periodical
providing timely and critical reviews of important topics in
computational chemistry as applied to all chemical disciplines.
Topics covered include quantum chemistry, molecular mechanics,
force fields, chemical education, and applications in academic and
industrial settings. Each volume is organized into (thematic)
sections with contributions written by experts. Focusing on the
most recent literature and advances in the field, each article
covers a specific topic of importance to computational chemists.
Annual Reports in Computational Chemistry is a 'must' for
researchers and students wishing to stay up-to-date on current
developments in computational chemistry.
Micro-Raman Spectroscopy introduces readers to the theory and application of Raman microscopy. Raman microscopy is used to study the chemical signature of samples with little preperation in a non-destructive manner. An easy to use technique with ever increasing technological advances, Micro-Raman has significant application for researchers in the fields of materials science, medicine, pharmaceuticals, and chemistry.
The knowledge base of chromatography continued to expand throughout
the 1990s owing to its many applications to problems of
contemporary interest in industry, life and environmental sciences.
Organizing this information into a single text for a diverse group
of scientists has become increasingly difficult. The present book
stemmed from the desire to revise Chromatography Today, written by
the same author with Salwa K. Poole, and published in 1991. This
title is considered to be one of the definitive texts on
chromatography. It was soon realized however, that a simple
revision would not provide the desired result of a contemporary
picture of the practice of chromatography at the turn of the
century. The only workable solution was to start afresh,
maintaining the same general philosophy and concept for
Chromatography Today where possible, while creating essentially a
new book.
This monograph focuses on modern femtosecond laser microscopes for two photon imaging and nanoprocessing, on laser tweezers for cell micromanipulation as well as on fluorescence lifetime imaging (FLIM) in Life Sciences. The book starts with an introduction by Dr. Wolfgang Kaiser, pioneer of nonlinear optics and ends with the chapter on clinical multiphoton tomography, the novel high resolution imaging technique. It includes a foreword by the nonlinear microscopy expert Dr. Colin Sheppard. Contents Part I: Basics Brief history of fluorescence lifetime imaging The long journey to the laser and its use for nonlinear optics Advanced TCSPC-FLIM techniques Ultrafast lasers in biophotonics Part II: Modern nonlinear microscopy of live cells STED microscopy: exploring fluorescence lifetime gradients for super-resolution at reduced illumination intensities Principles and applications of temporal-focusing wide-field two-photon microscopy FLIM-FRET microscopy TCSPC FLIM and PLIM for metabolic imaging and oxygen sensing Laser tweezers are sources of two-photon effects Metabolic shifts in cell proliferation and differentiation Femtosecond laser nanoprocessing Cryomultiphoton imaging Part III: Nonlinear tissue imaging Multiphoton Tomography (MPT) Clinical multimodal CARS imaging In vivo multiphoton microscopy of human skin Two-photon microscopy and fluorescence lifetime imaging of the cornea Multiscale correlative imaging of the brain Revealing interaction of dyes and nanomaterials by multiphoton imaging Multiphoton FLIM in cosmetic clinical research Multiphoton microscopy and fluorescence lifetime imaging for resection guidance in malignant glioma surgery Non-invasive single-photon and multi-photon imaging of stem cells and cancer cells in mouse models Bedside assessment of multiphoton tomography
Measurements and experiments are made each and every day, in fields as disparate as particle physics, chemistry, economics and medicine, but have you ever wondered why it is that a particular experiment has been designed to be the way it is. Indeed, how do you design an experiment to measure something whose value is unknown, and what should your considerations be on deciding whether an experiment has yielded the sought after, or indeed any useful result? These are old questions, and they are the reason behind this volume. We will explore the origins of the methods of data analysis that are today routinely applied to all measurements, but which were unknown before the mid-19th Century. Anyone who is interested in the relationship between the precision and accuracy of measurements will find this volume useful. Whether you are a physicist, a chemist, a social scientist, or a student studying one of these subjects, you will discover that the basis of measurement is the struggle to identify the needle of useful data hidden in the haystack of obscuring background noise.
These essays draw on recent and versatile work by museum staff, science educators, and teachers, showing what can be done with historical scientific instruments or replicas. Varied audiences - with members just like you - can be made aware of exciting aspects of history, observation, problem-solving, restoration, and scientific understanding, by the projects outlined here by professional practitioners. These interdisciplinary case studies, ranging from the cinematic to the hands-on, show how inspiration concerning science and the past can give intellectual pleasure as well as authentic learning to new participants, who might include people like you: students, teachers, curators, and the interested and engaged public. Contributors are Dominique Bernard, Paolo Brenni, Roland Carchon, Elizabeth Cavicchi, Stephane Fischer, Peter Heering, J.W. Huisman, Francoise Khantine-Langlois, Alistair M. Kwan, Janet Laidla, Pierre Lauginie, Panagiotis Lazos, Pietro Milici, Flora Paparou, Frederique Plantevin, Julie Priser, Alfonso San-Miguel, Danny Segers, Constantine (Kostas) Skordoulis, Trienke M. van der Spek, Constantina Stefanidou, and Giorgio Strano.
THIS VOLUME, WHICH IS DESIGNED FOR STAND-ALONE USE IN TEACHING AND
RESEARCH, FOCUSES ON QUANTUM CHEMISTRY, AN AREA OF SCIENCE THAT
MANY CONSIDER TO BE THE CENTRAL CORE OF COMPUTATIONAL CHEMISTRY.
TUTORIALS AND REVIEWS COVER
This manual is designed as an intensive introduction to the various
tools of molecular biology. It introduces all the basic methods of
molecular biology including cloning, PCR, Southern (DNA) blotting,
Northern (RNA) blotting, Western blotting, DNA sequencing,
oligo-directed mutagenesis, and protein expression. |
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