Russian popular-science writer Yakov Perelman makes physics fun in his classic book, offering real-world applications, demonstrations, and fascinating phenomena that remain relevant-and educational-to modern readers. This book explains many of the most entertaining aspects of the physical world and its principles, including optical illusions, light tricks and mirages, watermelon force, gravity and flight, travel to the moon, brain teasers, heat, boomerangs, "perpetual motion machines," echoes, and feats of strength.

Presented by Quid Pro Books as a "Digitally Remastered Book," (TM) this edition is unlike vintage republications that repeat printer errors or copying artifacts from the original. Instead, the process markedly reduces underlines, blotches, stray marks, and broken words. The effect retains and preserves the original presentation and its accuracy (unlike all-new renderings which introduce scan/OCR error), while offering a more complete and pleasant reading experience . . . to a new generation of students and curious readers.

The first book on the topic, with each chapter written by pioneers in the field, this essential resource details the fundamental theory, applications, and future developments of liquid cell electron microscopy. This book describes the techniques that have been developed to image liquids in both transmission and scanning electron microscopes, including general strategies for examining liquids, closed and open cell electron microscopy, experimental design, resolution, and electron beam effects. A wealth of practical guidance is provided, and applications are described in areas such as electrochemistry, corrosion and batteries, nanocrystal growth, biomineralization, biomaterials and biological processes, beam-induced processing, and fluid physics. The book also looks ahead to the future development of the technique, discussing technical advances that will enable higher resolution, analytical microscopy, and even holography of liquid samples. This is essential reading for researchers and practitioners alike.

This manual is designed as an intensive introduction to the various tools of molecular biology. It introduces all the basic methods of molecular biology including cloning, PCR, Southern (DNA) blotting, Northern (RNA) blotting, Western blotting, DNA sequencing, oligo-directed mutagenesis, and protein expression.
Key Features
* Provides well-tested experimental protocols for each technique
* Lists the reagents and preparation of each experiment separately
* Contains a complete schedule of experiments and the preparation required
* Includes study questions at the end of each chapter

Books of Related Interest From Van Nostrand Reinhold Carcinogenically Active Chemicals A Reference Guide By Richard J. Lewis, Sr., 1088 pages, 7 x 10, ISBN 0-442-31875-8 More than 3400 chemicals verified or suspected as carcinogens are listed in this massive sourcebook. Data on each chemical are drawn from leading cancer research and regulatory agencies, and based on animal experiments, human case histories, or conclusions of expert review groups. Each entry contains experimental data relating to the carcinogenicity or mutagenicity of the entry with literature citations, and includes the conclusions of IARC, OSHA, ACGIH, DFG MAK, and NIOSH. Indexes are provided on human tumor sites, synonyms, CAS numbers, and a complete reference list is included. Hazardous Chemicals Desk Reference Second Edition By Richard J. Lewis, Sr., 1100 pages, 7 x 10, ISBN 0-442-00497-4 This complete update and revision of the renowned First Edition provides immediate access to vital information on approximately 5000 hazardous chemicals and compounds commonly used in industry, manufacturing, laboratories, and the workplace. Entries feature a concise review of toxicity and other hazards, including a helpful 1-to-3 hazard rating, important reference information such as chemical synonyms and CAS, NIOSH, and DOT number identifiers, standards for exposure limits, and general physical properties. The toxic and hazard review paragraph for each entry offers a detailed analysis of poisonous, irritant, corrosive, explosive, and carcinogenic properties. The entries provide a reliable guide to a full spectrum of short term and chronic human health effects associated with improper handling and exposure to these chemicals. Dangerous Properties of Industrial Materials Seventh Edition By N. Irving Sax and Richard J. Lewis, Sr., 4283 pages, 3 volumes, 8 1/2 x 11, ISBN 0-442-28020-3 This classic reference has been thoroughly revised and updated. It now provides more than 20,000 chemical entries, as compared to 18,000 entries offered in the Sixth Edition. Every entry has been reviewed and brought up-to-date, with physical properties checked, clinical data reviewed, synonyms added, and cross-references to the latest issues of Dangerous Properties of Industrial Materials Report included. Exposure standards have also been revised and expanded to include OSHA PELS, ACGIH Threshold Limit Values, Short- Term Exposure Limits, Biological Exposure Indices, and Maximum Allowable Concentrations (from the German Research Institute). Food Additives Handbook By Richard J. Lewis, Sr., 600 pages, 6 7/8 x 10, ISBN 0-442-20508-2 More than 1350 food additives, including direct and indirect additives, packaging materials, and pesticide residue, are covered in this handbook. Wide-ranging information on each additive includes physical properties, generic use, foods where used, hazards to the consumer and worker who handles large quantities and usage regulations. Key data are provided on unintentional additionals. Safety and nutritional issues relevant to add are discussed. Two sets of cross indexes speed up access.

This market-leading manual for the first-year physics laboratory course offers a wide range of class-tested experiments designed specifically for use in small to mid-size lab programs. A series of integrated experiments emphasizes the use of computerized instrumentation and includes a set of "computer-assisted experiments" that allow you to gain experience with modern equipment. By analyzing data through two different methods, learners gain a greater understanding of the concepts behind the experiments. The Eighth Edition is updated with four new economical labs and thirty new Pre-Lab Demonstrations, designed to capture interest prior to the lab and requiring only widely available materials and items.

A treatment of the experimental techniques and instrumentation most often used in nuclear and particle physics experiments as well as in various other experiments, providing useful results and formulae, technical know-how and informative details. This second edition has been revised, while sections on Cherenkov radiation and radiation protection have been updated and extended.

Effective science communication is no easy task. While the effective conveyance of technical knowledge presents formidable roadblocks to sharing scientific knowledge and discoveries, certain communication tools like video and film production help to bridge this gap. This user's manual provides a complete set of easy-to-follow directions for video-making as well as tricks of the trade to leverage these skills to better inform the intended audience.

How One Man Invented a Color That Changed the World

"Garfield's engaging story of William Perkin's accidental discovery is an informative mix of science, history, and biography."—Boston Herald

In 1856 eighteen-year-old English chemist William Perkin accidentally discovered a way to mass-produce color. In a "witty, erudite, and entertaining" (Esquire) style, Simon Garfield explains how the experimental mishap that produced an odd shade of purple revolutionized fashion, as well as industrial applications of chemistry research. Occasionally honored in certain colleges and chemistry clubs, Perkin until now has been a forgotten man. 8 pages of color illustrations.

"By bringing Perkin into the open and documenting his life and work, Garfield has done a service to history."—Chicago Tribune

"[A]n inviting cocktail of Perkin biography, account of the dye industry and where it led, and social and cultural history up to the present."—American Scientist

"Garfield leaps gracefully back and forth in time, as comfortable in the Victorian past as he is in the brave new world of petrochemicals and biochemistry."—Kirkus Reviews starred review.

"[T]he delight of this book is seeing parallels to present-day trends."—"New York Times Book Review

Over the past decade, advances in the field of close-range photogrammetry have been rapid and the era of digital photogrammetry is well on its way. This book provides a complete account of the subject with contributions from international experts.;The methodology, algorithms, techniques and equipment necessary to achieve real-time digital photogrammetric solutions are presented, together with contemporary aspects of close-range photogrammetry. Advances in the theory are presented as are a range of important applications of photogrammetry which illustrate the flexibility and comprehensive nature of these techniques of three-dimensional measurement.

The definitive guide to the principles and practice of experimental organic chemistry - fully updated and now featuring more than 100 experiments The latest edition of this popular guide to experimental organic chemistry takes students from their first day in the laboratory right through to complex research procedures. All sections have been updated to reflect new techniques, equipment and technologies, and the text has been revised with an even sharper focus on practical skills and procedures. The first half of the book is devoted to safe laboratory practice as well as purification and analytical techniques; particularly spectroscopic analysis. The second half contains step-by-step experimental procedures, each one illustrating a basic principle, or important reaction type. Tried and tested over almost three decades, over 100 validated experiments are graded according to their complexity and all are chosen to highlight important chemical transformations and to teach key experimental skills. New sections cover updated health and safety guidelines, additional spectroscopic techniques, electronic notebooks and record keeping, and techniques, such as semi-automated chromatography and enabling technologies such as the use of microwave and flow chemistry. New experiments include transition metal-catalysed cross-coupling, organocatalysis, asymmetric synthesis, flow chemistry, and microwave-assisted synthesis. Key aspects of this third edition include: * Detailed descriptions of the correct use of common apparatus used in the organic laboratory * Outlines of practical skills that all chemistry students must learn * Highlights of aspects of health and safety in the laboratory, both in the first section and throughout the experimental procedures * Four new sections reflecting advances in techniques and technologies, from electronic databases and information retrieval to semi-automated chromatography * More than 100 validated experiments of graded complexity from introductory to research level * A user-friendly experiment directory * An instructor manual and PowerPoint slides of the figures in the book available on a companion website A comprehensive guide to contemporary organic chemistry laboratory principles, procedures, protocols, tools and techniques, Experimental Organic Chemistry, Third Edition is both an essential laboratory textbook for students of chemistry at all levels, and a handy bench reference for experienced chemists.

We cannot imagine a world without plastics. Plastic products make our daily life safe, healthy and convenient. Besides all the benefits, the current plastics economy gives rise to environmental concerns with respect to fossil oil depletion and plastic waste accumulation. In a circular economy, however, plastics can be redesigned for reusability and recyclability. This book makes the topic of sustainable plastics approachable for students and career starters alike, describing the nature and chemistry of (bio)polymers as well as how to create a closed loop of plastic materials.

Written for animal researchers, this book provides a comprehensive guide to the design and statistical analysis of animal experiments. It has long been recognised that the proper implementation of these techniques helps reduce the number of animals needed. By using real-life examples to make them more accessible, this book explains the statistical tools employed by practitioners. A wide range of design types are considered, including block, factorial, nested, cross-over, dose-escalation and repeated measures and techniques are introduced to analyse the experimental data generated. Each analysis technique is described in non-mathematical terms, helping readers without a statistical background to understand key techniques such as t-tests, ANOVA, repeated measures, analysis of covariance, multiple comparison tests, non-parametric and survival analysis. This is also the first text to describe technical aspects of InVivoStat, a powerful open-source software package developed by the authors to enable animal researchers to analyse their data and obtain informative results.

By closing the gap between general programming books and those on laboratory automation, this timely book makes accessible to every laboratory technician or scientist what has traditionally been restricted to highly specialized professionals. Following the idea of "learning by doing", the book provides an introduction to scripting using AutoIt, with many workable examples based on real-world scenarios. A large portion of the book tackles the traditionally hard problem of instrument synchronization, including remote, web-based synchronization. Automated result processing, database operation, and creation of graphical user interfaces are also examined. Readers of this book can immediately profit from the new knowledge in terms of both increased efficiency and reduced costs in laboratory operation. Above all, laboratory technicians and scientists will learn that they are free to choose whatever equipment they desire when configuring an automated analytical setup, regardless of manufacturers suggested specifications.

Data Processing Handbook for Complex Biological Data provides relevant and to the point content for those who need to understand the different types of biological data and the techniques to process and interpret them. The book includes feedback the editor received from students studying at both undergraduate and graduate levels, and from her peers. In order to succeed in data processing for biological data sources, it is necessary to master the type of data and general methods and tools for modern data processing. For instance, many labs follow the path of interdisciplinary studies and get their data validated by several methods. Researchers at those labs may not perform all the techniques themselves, but either in collaboration or through outsourcing, they make use of a range of them, because, in the absence of cross validation using different techniques, the chances for acceptance of an article for publication in high profile journals is weakened.

Data Fitting in the Chemical Sciences Peter Gans, School of Chemistry, The University of Leeds, Leeds, UK Data fitting is a technique of central importance in modern experimental science. It is the means by which data is tested against a model of the experimental system, be it a theoretical or empirical model. In this book an all-round approach is adopted in which the first stage of data-fitting is seen as data collection, the second is numerical processing and the third a critical evaluation of the 'goodness' of fit in both statistical and common sense terms. Each stage is considered in detail: the sources and nature of experimental errors; the theory of least-squares fitting; probability theory; hypothesis testing, and the application of scientific criteria. The theory is complemented by three chapters on a wide range of applications. The emphasis of this book is on methodology: why certain procedures are preferred rather than how any one procedure is implemented. The author aims to assist people in extracting from their data its full information content, i.e. to use their data, not abuse it.

For those new to this technique, this guide provides basic tips, key skills, awareness and guidance on good practice of High Performance Liquid Chromatography (HPLC). It will help build understanding of the important issues to consider during analysis and how to develop further skills. HPLC is one of the most widely used techniques in industry to separate and analyse compounds through the mass transfer of analytes between stationary and mobile phases. This guide will prove an invaluable introduction to the technique. Starting with a look at the basic theory, the guide goes on to describe HPLC components, system parameters, suitability checks and testing. Later sections cover calibration, problem solving and data handling. High Performance Liquid Chromatography is one of the Practical Laboratory Skills Training Guides, a series that aims to make achieving best practice easy. These invaluable manuals will enable both experienced and inexperienced staff to get the essential basics of any experiment right simply by following the clear and easy to use instructions provided. The guides are written by experienced scientists and include minimal theory, plenty of practical exercises in order to assess competence, and trouble shooting information. Other titles are: Measurement of Mass; Measurement of Volume; Measurement of pH; and Gas Chromatography.

From building a bridge and crafting an automaton to making a guitar and creating a crane, Science Lab is packed with activities that young readers can do at home to explore, discover, and understand the way the world works.

How do boats stay afloat? How can seals stay warm in very cold temperatures? How can you make a ball levitate? With fun, hands-on projects and experiments, this book reveals how science, technology, engineering, and maths are woven through the world around us.

Simple steps guide readers through the stages of each project, with spotlights on the key science, technology, engineering, and maths learning involved in each project along the way. "Test and tweak" panels encourage young readers to experiment and take their projects to the next level, developing their independence, initiative, and creative thinking skills.

With a focus on STEM subjects (science, technology, engineering, and maths) across school curricula to prepare children for the modern world, Science Lab will inspire and engage inquisitive young readers. It's perfect for school projects, homework help, and firing up imaginations.

Bestselling author Theodore Gray has spent more than a decade dreaming up, executing, photographing, and writing about extreme scientific experiments, which he then published between 2009 and 2014 in his monthly Popular Science column "Gray Matter." Previously published in book form by Black Dog in two separate volumes (Mad Science and Mad Science 2), these experiments, plus 5 more all-new ones, will now be combined in one complete book. Packaged in a smaller, chunkier format Completely Mad Science is 432 pages of dazzling chemical demonstrations, illustrated in spectacular full-color photographs. Some of the completely mad experiments in the book include: Casting a model fish out of mercury (demonstrating how this element behaves very differently depending upon temperature); the famous Flaming Bacon Lance that can cut through steel (demonstrating the amount of energy contained in fatty foods like bacon); creating nylon thread out of pure liquid by combining molecules of hexamethylenediamine and sebacoyl chloride; making homemade ice cream using a fire extinguisher and a pillow case; powering your iPhone using 150 pennies and an apple, and many, many more. It's the ultimate collection for Gray's millions of fans.

About 40 % of current atomic force microscopy (AFM) research is performed in liquids, making liquid-based AFM a rapidly growing and important tool for the study of biological materials. This book focuses on the underlying principles and experimental aspects of AFM under liquid, with an easy-to-follow organization intended for new AFM scientists. The book also serves as an up-to-date review of new AFM techniques developed especially for biological samples. Aimed at physicists, materials scientists, biologists, analytical chemists, and medicinal chemists. An ideal reference book for libraries. From the contents: Part I: General Atomic Force Microscopy * AFM: Basic Concepts * Carbon Nanotube Tips in Atomic Force Microscopy with * Applications to Imaging in Liquid * Force Spectroscopy * Atomic Force Microscopy in Liquid * Fundamentals of AFM Cantilever Dynamics in Liquid * Environments * Single-Molecule Force Spectroscopy * High-Speed AFM for Observing Dynamic Processes in Liquid * Integration of AFM with Optical Microscopy Techniques Part II: Biological Applications * DNA and Protein-DNA Complexes * Single-Molecule Force Microscopy of Cellular Sensors * AFM-Based Single-Cell Force Spectroscopy * Nano-Surgical Manipulation of Living Cells with the AFM

Analytical techniques are powerful tools in a chemist's armoury and this book identifies some of the most important chemical techniques currently in use, along with their applications. Aimed at those with some familiarity with modern chemical techniques, as well as those completely new to them, the book covers much of the basic theory without emphasising the mathematics and physics involved. Where appropriate, descriptions of the instrumentation and sample preparation are included, as are problems with example solutions. More advanced ideas are presented in highlighted boxes, so the novice can happily skip these if desired. Modern Chemical Techniques is based on a series of 'hands-on' symposia that enabled individuals to update their chemical skills and learn about the newest methods, techniques, and instrumentation available. The resource material presented at the symposia is published here, developed and extended into an accessible, illustrated book, making the valuable information it contained available to a much wider audience.

This issue of Dermatologic Clinics, guest edited by Jane M. Grant-Kels, Giovanni Pellacani, and Caterina Longo, is devoted to Confocal Microscopy. Articles in this timely issue include: Basics of Confocal Microscopy and the Complexity of Diagnosing Skin Tumors: New Imaging Tools in Clinical Practice, Diagnostic Workflows, Cost-estimate and New Trends; Opening a Window Into Living Tissue: Histopathologic Features of Confocal Microscopic Findings in Skin Tumors; Addressing the Issue of Discriminating Nevi from Early Melanomas: Dues and Pitfalls; Melanoma Types and Melanoma Progression: The Different Faces; Lentigo Maligna, Macules of the Face and Lesions on Sun-damaged Skin: Confocal makes the Difference; Glowing in the dark: use of confocal microscopy in dark pigmented lesions; Enlightening the Pink: Use of Confocal Microscopy in Pink Lesions; Shining into the White: The Spectrum of Epithelial Tumors from Actinic Keratosis to SCC; Application of Wide-probe and Handy-probe for Skin Cancer Diagnosis: Pros and Cons; Confocal Microscopy for Special Sites and Special Uses; Confocal Algorithms for Inflammatory Skin Diseases and Hair Diseases; In Vivo and Ex Vivo Confocal Microscopy for Dermatologic and Mohs' Surgeons; Telediagnosis with Confocal Microscopy: A Reality or a Dream?; "Well-aging": Early Detection of Skin Aging Signs; The Role of Confocal Microscopy in Clinical Trials for Treatment Monitoring; and Fluorescence (multiwave) Confocal Microscopy.

Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.