This well-written text thoroughly addresses two quality of life issues in patients with a variety of neurological disorders: sexual and reproductive function. The de vasta stating effects of a variety of neurological diseases are well known to both the lay and medical communitIes, and are treated in numerous texts. However, as we continue to experience therapeutic breakthroughs in the tields of neurology and rehabilitation medicine, physicians and patients must become more aware of the issues discussed in this text. It is particularly important, as emphasized throughout the chapters, that the physician or therapist initiate conversations with the patients concerning both the possibility of parenting a child, as well as the ability of the patient to enhance his/her sexual functioning. Commonly in the patient who is otherwise perfectly normal, there is a reluctance to discuss these topics and couples often feel embarrassed to initiate a conversation with their physi cians. This reluctance to initiate a discussion is even more apparent in patients with a variety of neurological disorders, in which there are overriding fears concerning both function and survival, as well as deep concerns about their own attractiveness, and their sexual and repro ductive ability."

'Raw. Vulnerable. Open. Truthful . . . This is a book that will open up the floor for even more honest conversations about the side of yoga we don't often see.' - Angie Tiwari @tiwariyoga How did an ancient spiritual practice become the preserve of the privileged? Nadia Gilani has been practising yoga for twenty-five years. She has also worked as a yoga teacher. Yoga has saved her life and seen her through many highs and lows; it has been a faith, a discipline, and a friend, and she believes wholeheartedly in its radical potential. However, over her years in the wellness industry, Nadia has noticed not only yoga's rising popularity, but also how its modern incarnation no longer serves people of colour, working class people, or many other groups who originally pioneered its creation. Combining her own memories of how the practice has helped her with an account of its history and transformation in the modern west, Nadia creates a love letter to yoga and a passionate critique of the billion-dollar industry whose cost and inaccessibility has shut out many of those it should be helping. By turns poignant, funny, and shocking, The Yoga Manifesto excavates where the industry has gone wrong, and what can be done to save the practice from its own success.

Sunshine plays an important role in all aspects of life but there has been little social analysis of the sun and its place in our world. Recently experts have warned us that the sun's rays are dangerous. Yet, a suntan can still be taken as a sign of health. How did we arrive at this ambivalent relationship to the sun and what does this say about our changing attitudes to the human body and environment? Rise and Shine takes as its starting point a view of sunlight as part of our material and social culture. How did the use of sunlight to treat tuberculosis and rickets in the early twentieth century alter our relationship with the sun? When was suntan lotion invented? By drawing on a range of archival and historical sources, Rise and Shine traces the network of social and medical forces that constitute our current, sometimes problematic, relationship with sun and sunlight.

A must for parents, teachers and counselors, this book targets preadolescent girls aiming to engage them in educational activites that will empower them to avoid eating disorders. The author examines eating disorders from sociocultural and feminist perspectives showing how disorders are most often caused by overexposure to media messages, an unrealistic cultural fascination with thinness, by continuous anaylsis of our bodies and a disordered cultural view of food. Then Menassa presents a 10-session guide to prevention that engages girls in activities to spur and empower their independent thinking and reasoning. For example, girls become watchdogs of the media and write to companies that present women in a negative light in their advertisements. The girls challenge ingrained beliefs and replace them with healthier ones. Preadolescence is a time when girls' minds are malleable and they are willing to challenge established activities, such as media presentations. Once girls hit puberty, many will have already developed disordered eating behaviors; many will have been on several diets; therefore, beginning the work to decode and combat harmful messages before that stage is crucial.

Authors are very experienced in the field Techniques are easy to follow and comprehensive allowing therapists to direct families to continue exercises at home Additional printable resources for families Testimonials from families supported by the Total Speech approach are included The advantage of the proposed book is the combining of clinical experience with describing techniques that are not commonly used or acknowledged (i.e. using tactile input in addition to auditory and visual) to support the speech of children with additional or complex needs.

This volume features contributions from participants of the ESRF symposium on "Immunotherapy in 2020a "Visions and Trends for Targeting Inflammatory Diseases" held in Potsdam near Berlin, Germany, in October 2006.

The symposium presentations covered the main mechanisms of immunoregulation such as peripheral and central tolerance, epigenetic programming, immunologic memory, and regulatory networks in inflammation as well as novel experimental and clinical approaches for targeting inflammation in autoimmunity and transplantation. An important related question is how recent findings in immunological research can lead to improved diagnostics, new drugs, and better therapies. The targeting of novel pathways and immunoregulatory mechanisms, the challenge of immunologic memory for lastingly successful anti-inflammatory therapy, new approaches for adoptive T cell and polyclonal antibody therapies, and the individualization of immunomodulatory therapies are thereby topics of this volume.

From the President of the Research Society on Alcoholism The sixteenth volume of Recent Developments in Alcoholism contains the latest information on the field of alcoholism treatment research. This scholarly volume includes comprehensive reviews of the methodologies available to evaluate treatment outcome, state-of-the art psychosocial interventions, and recent advances in pharmacological adjuncts to treatment that are currently available and those on the brink of application. Other sections of the book address special issues in the treatment of alcohol dependence, including the treatment of the adolescents and other unique populations, the management of tobacco dependence, and the role of spirituality in recovery, among others. The clinician will find these reviews an important resource for learning about e- dence based treatments for alcoholism, and the researcher will find the synt- sis of recent developments informative and forward looking. The research agenda for the future rests soundly on the progress to date and additional advances in the treatment of alcoholism can be predicted in the near future. Stephanie O'Malley, Ph. D. President, Research Society on Alcoholism xi Preface From the President of the American Society of Addiction Medicine This excellent volume presents investigations covering a wide spectrum of scientific issues. It is also evident that many of these articles have clinical s- nificance, ranging from assessments of disorder, monitoring clinical progress, and behavioral and pharmacological interventions.

This book is the first to take into account the rapidly growing body of knowledge on the relation between sleep and PD. Gathering contributions from internationally recognized experts, it provides a unique source of in-depth information on sleep and circadian dysregulation in Parkinson's disease. The book is divided into two parts: the first comprises chapters on normal sleep-wake homeostasis, followed by changes that occur in PD and discussions of available tools for the assessment of sleep-wake cycles in PD. In the second part, sleep and circadian disorders associated with PD are described in individual chapters, including sections on epidemiology, etiology, pathogenesis, differential diagnosis, and treatment. Controversies in the field, such as the relations between cognition and sleep, fatigue and sleepiness, and the potential impact of surgical therapies on sleep-wake cycles are discussed separately. The book closes with a chapter on future directions and unmet needs in the field of sleep, circadian biology and PD. This comprehensive text offers a readily accessible resource for clinicians and researchers alike, addressing the needs of neurologists, sleep and movement disorders specialists, and all trainees and allied health professionals involved in the care of patients affected by Parkinson's disease.

Principles and Applications of Therapeutic Ultrasound in Healthcare introduces concepts, principles, construction, and applications of therapeutic ultrasound: from bench to bedside. A comprehensive examination of the industry and medical application of ultrasound therapy, this book highlights working principles, research progress, and system structures of therapeutic ultrasound. It describes the principles of therapeutic ultrasound, details the system construction, introduces current and emerging applications, and discusses developing therapeutic ultrasound technologies. Divided into two parts, the book first introduces the fundamentals of biomedical acoustics, discusses ultrasound calibration methods, and the structures of available therapeutic ultrasound systems before moving on to the various applications of ultrasound therapy used in clinics. It includes a variety of extensive clinical trials, outcome photos and illustrating figures, and a critical commentary on the challenges in this field. The author discusses topics that include: The derivation of wave equation The mathematical solution of the wave propagation The phenomena of reflection Refraction and transmission in the acoustic field from different acoustic sources The radiation pattern of the ultrasound transducer The acoustical properties of biological tissues Ultrasound-induced bioeffects Cavitation The design of the ultrasound transducer The characterization method of the produced acoustic field An easy reference offering full coverage of popular ultrasound therapies, Principles and Applications of Therapeutic Ultrasound in Healthcare provides a simple explanation of fundamental acoustics, including wave equation, propagation, nonlinearity, and transducer design. It also discusses other potential applications, and is geared toward academia, industry, and researchers.

It was during the course of the eighteenth and nineteenth centuries that the problem of chronic alcohol dependence in modern society and its consequent medical effects emerged. The topic of drunkenness figures prominently in the thinking and writing of social reformers, politicians, theorists, medical practitioners, and psychiatrists. Eventually, by the mid-nineteenth century, 'alcoholism' was named as the disease of habitual drunkenness. Possibly the most important book to predict this was Trotter's Essay, written in 1804. Through case studies based on wide experience, he detailed the manifestations of alcoholism, ventured therapeutic recommendations, and squarely termed drunkenness a disease - indeed, a mental disease. Originally published in 1988 as part of the Tavistock Classics in the History of Psychiatry series, Roy Porter's Introduction to this facsimile reprint locates Trotter's work within the wider history of the evolution of the idea of alcoholism. It also examines the Essay in the context of Trotter's own life and mind - a mind preoccupied with what he saw as the degenerative tendencies of modern civilization and with the wider issues of drug dependence.

Expanding Receptive and Expressive Skills through Stories (EXPRESS): Language Formulation in Children with Selective Mutism and Other Communication Needs is a resource that provides a specific treatment approach for professional speech-language pathologists working with children with selective mutism and other language delays or disorders including language learning disabilities, autism spectrum disorders, or for children learning English as a second language. It is a program for expanding receptive and expressive language skills at varying stages of language development, with five levels of communication to allow the clinician to start at the appropriate level for each child, and progress through the levels.The "EXPRESS" approach includes activity modules corresponding to classic children's stories. Children's literature is used as a tool for presenting activities designed to help children learn specific language skills, and supports the Common Core State Standards. Each of the modules requires the corresponding storybook that can be obtained individually or found within "The 20th Century Children's Book Treasury", a compendium that includes all the stories.Using "EXPRESS", children listen to the stories and through the activities presented acquire key concepts, ideas, and details about the material. Vocabulary is enhanced through drawing, describing, and demonstration. Children also have an opportunity to make inferences from the textual material through the question-answer routines developed for each story. Creativity and imagination are fostered using sentence formulation and story generation. "EXPRESS" also includes forms to help the clinician monitor progress and a PluralPlus companion website with video links to the stories and downloadable items from the book such as activity cards and scoring sheets.

Currently a great deal of public discourse around health is on the assumed relationship between childhood inactivity, young people's diets, and a putative steep rise in obesity. Children and young people are increasingly being identified as a population at 'risk' in relation to these health concerns. Such concerns are driving what might be described as new 'health imperatives' which prescribe the choices young people should make around lifestyle: physical activity, body regulation, dietary habits, and sedentary behaviour. These health imperatives are a powerful force driving major policy initiatives on health and education in a number of countries in the Western world. Schools in particular have been targeted for the implementation of a plethora of initiatives designed to help children and young people lose weight, become more active and change their eating patterns inside and outside school. Addressing these issues requires an innovative theoretical approach. Neither the fields of 'eating disorders' nor 'obesity research' has addressed these issues from a sociological and pedagogical perspective. The contributors to this edited collection draw on a range of social theories, including Michel Foucault and Basil Bernstein to interpret the data collected across three countries (Australia and New Zealand, United Kingdom) and from a range of primary and secondary schools. Each chapter addresses various aspects of the relationship between health imperatives as constituted in government policies, school programs and practices, their recontextualised in school practices and the impact of this on the subjectivities of children and teachers. This book was originally published as a special issue of Discourse: Studies in the Cultural Politics of Education.

This book examines the rehabilitation of language disorders in adults, presenting new research, as well as expert insights and perspectives, into this area. The first chapter presents a study on personalised cueing to enhance word finding. Cynthia K. Thompson and her colleagues contribute a chapter describing The Northwestern Naming Battery and its use in examining for verb and noun deficits in stroke-induced and primary progressive aphasia. Heather Harris-Wright and Gilson J. Capilouto examine a multi-level approach to understanding the maintenance of global coherence in aphasia. Kathryn M. Yorkston and colleagues provide discussion on the training of healthcare professionals, and what speech and language pathology and medical education can learn from one another. Yorkston also presents a systematic review asking whether principles of motor learning can enhance retention and transfer of speech skills. Connie A. Tompkins present a single-participant experiment examining generalization of a novel treatment for coarse coding deficit in right hemisphere damage. Finally, Chris Code returns to the topic of apportioning time for aphasia treatment. This book was originally published as a special issue of Aphasiology.

"After decades of research on dysfunctional eating and lack of physical activity, research attention has finally turned to the role of digital technology in eating behaviors and eating disorders. This timely volume offers a thoughtful and wide collection of chapters discussing the possible effects of digital technologies, from those enhancing healthy eating behaviors to those that encourage disordered eating. Highly recommended for both professionals and scholars." Prof. Giuseppe Riva, Universita Cattolica del Sacro Cuore, Milan, Italy. This book examines in depth the multifaceted roles of digital technologies in the eating behaviors and eating disorders. Coverage reflects a broad theoretical and empirical knowledge of current trends in digital technology use in health behaviors, and their risks and benefits affecting wellbeing, with focus on eating behaviors and eating disorders. The authors use both qualitative and quantitative data to focus on the digital lived experiences of people and their eating related behaviors. Among the topics covered: The quality of eating-oriented information online Technology, body image, and disordered eating Eating-oriented online groups Using mobile technology in eating behaviors Usage of digital technology among people with eating disorders What healthcare professionals should know about digital technologies and eating disorders Technology-based prevention and treatment programs for eating disorders A potential source of discussion and debate in various fields across the social sciences, the health sciences, and psychology, Digital Technology, Eating Behaviors, and Eating Disorders will be especially useful to students, academics, researchers, and professionals working in the fields of eating behaviors and eating disorders.

Alcohol use is complex and multifaceted. Our understanding must be also. Alcohol use, both problematic and not, can be understood at many levels - from basic biological systems through to global public health interventions. To provide the multi-level perspective needed to address this complexity, the Handbook of Alcohol Use draws together an eclectic set of authors, including both researchers and practitioners, to examine the causes, processes and effects of alcohol consumption. Specifically, this book approaches the topic from biological, individual cognition, small group/systems, and domestic/global population perspectives. Each examines alcohol use differently and each offers its own ways to combat problematic behavior. While these alternative viewpoints are sometimes construed as incompatible or antagonistic, the current volume also explores how they can be complimentary. In summary, the Handbook of Alcohol Use brings together an international group of experts to explore how alcohol use can be understood from various perspectives and how these conceptualizations relate. In doing so, it allows us to understand alcohol consumption, and our responses to it, more from an account which spans 'from synapse to society'.

This latest addition to the Methods in Molecular Medicine series, Anti- ral Methods and Protocols, is opportune because there is an increasing int- est in discovering compounds that are effective against both chronic and acute viral infections. A number of the methods described in the volume are unp- lished and their inclusion indicates the speed at which this field is moving. This volume is not a review but each chapter contains methods validated by the experts who have spent time in developing the protocols. The hallmark of this series is the comprehensive way in which the me- ods are described, which includes a list of all the reagents needed for each protocol. Of importance is the section on tips and pitfalls that the authors have discovered while developing their protocols. The manual itself is designed to be used by researchers in universities and industry who are familiar with a range of biological techniques but who want to set up quickly a novel assay system. We encourage a dialog between readers and authors, which may also result in useful collaborations.

Aerosol therapy has significantly improved the treatment of a variety of respiratory diseases. Besides the treatment of respiratory diseases there is currently also a great interest to use the lungs as a portal to introduce drugs for systemic therapy.
The success of therapy with the application of aerosolized medicaments depends on the possibility to deliver the proper amount of drug to the appropriate sites in the respiratory system, thus limiting the side effects to a minimum. Aerosolized delivery of drugs to the lung is optimized if, for a given chemical composition of a medicine, the target of deposition and the required mass of drug to be deposited are precisely defined.
The next step is the specification of the number of respirable particles or droplets, to be generated by appropriate devices. Another very important factor for successful aerosol therapy is the condition of the patient coupled with his or her inhalation technique.

A former drug addict turned behavioural neuroscientist reveals how drugs work in the brain ― and what we can do to fight addiction.

Judith Grisel was a daily drug user when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey.

In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Delving into the science of one of the world’s most pressing health problems, she reveals what is different about the brains of addicts even before they first pick up a drink or drug, and highlights the changes that take place in the brain and behaviour as a result of chronic using.

With compassion and clarity, Grisel describes what drove her to addiction, what helped her recover, and her belief that a ‘cure’ for addiction will not be found in our individual brains but in the way we interact with our communities.

It was during a pleasant and warm (both literally and figuratively) two- week period in October, 1991 that a number of researchers, scholars and c1inicians from diverse lands gathered at the beautiful Chateau de Bonas, near Toulouse, France to discuss psychological, neuropsychological and neurolinguistic aspects of reading and writing disorders. The occasion for the serious disputations of theories, research findings and c1inical appli- cations was the Advanced Study Institute (ASI) under the auspices of the Scientific Affairs Division of the North Atlantic Treaty Organization (NATO). There was much sharing of mutual experiences, and considerable debate on some issues. There were also friendly exchanges, 'international' ping-pong, tennis matches, and bicyc1e races, and even some convivial- ity akin to that of a c1ass reunion with members telling their stories of yesterday and visions of tomorrow. All these serious scientific disputations and the friendly exchanges would not have been possible without the major assistance from NATO and other institutions and individuals. We wish to express our deep appre- ciation to Dr. L. v. da Cunha ofNATO Scientific Affairs Division, Dr. Tilo Kester and Mrs. Barbara Kester of the International Transfer of Science and Technology (ITST) for their active support and substantial assistance throughout the Advanced Study Institute; Mr. Charles Stockman and his staff of the Chateau de Bonas for looking after our stay there; Christi Martin and Xi-Wu Feng of Oklahoma State University, and the University of Saskatchewan generally for facilitating our work.

Nick Charles MBE is a pioneer in treating alcohol dependency. As the founder of both the Chaucer Clinic and the Gainsborough Foundation, he was the first person to be honoured by the Queen 'for services to people with alcohol problems' and his work - over four decades - has helped tens of thousands of people. But Nick's decorated success overlays an extraordinary and unforgettable personal journey, for Nick was once an alcoholic vagrant sleeping rough on the streets of London. In 50 Years of Hard Road, Nick details his time in the abyss of alcohol addiction; a period that despatched relationships, his health, his career, and so much more. Forced to live on the streets for four years, Nick recalls the tough times, the characters he met, and the ever-present call of alcohol, but also how he slowly built up two carrier bags-worth of painstaking research into alcohol and its effects on his fellow man. It was through the documents in these carrier bags that Nick's life was to change forever when, in the mid-1970s, he was taken under the wing of a doctor who cared for those on skid row. This dedicated medic recognised the treasure trove of information Nick had developed. 50 Years of Hard Road is a remarkable, uplifting, and often humorous story of one man's journey from the depths of life-crushing alcohol dependency, to running alcohol clinics and programmes across the country. It describes an incredible life filled with high points, low points, and amazing adventures in-between.

Alcoholism: A Review of Its Characteristics, Etiology, Treatment, and Controversies provides an accurate picture of the current state of research and treatment effectiveness in the field of alcoholism. Using compelling evidence, Irving Maltzman describes how the field has been distorted by the behavior therapy approach. A distinguished experimental psychologist at the University of California, Los Angeles, Professor Maltzman has written a comprehensive, important work marked by incisive argument. Alcoholism is an excellent reference for academics as well as professionals working in addictions treatment.