A comprehensive overview of major 12-step programs, this practical manual also describes the nuances of the various programs that address the same addictive behavior to assist the clinician in assessing and referring clients to any 12-step program. One of the unique features of this book is a description of how 12-step program philosophy aligns with eight major psychotherapy orientations. Another feature is the integration of the client's individual needs and ego structure with the appropriateness and timing of a referral to a 12-step program within the overall therapeutic process.

In this day of managed care, it is essential for clinicians to make informed referrals. This book bridges the gap between the desire to refer and a comprehensive understanding of the intricacies of the various programs. Through the use of detailed description, case vignettes, and clinical examples, this book proves an invaluable resource assisting clinicians to guide their clients through the process of integrating psychotherapy with adjunctive 12-step program involvement. Also included is a description of terms used in 12-step programs that allows the clinicians to join the client in a common language.

Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances.

This volume, is developed from a collaborative study sponsored by the World Health Organization over a period of five years, the result of the combined effort of over 30 experts working in 19 different countries. The book presents a comprehensive survey of the development, policy, and procedures of methadone maintenance in countries with experience in this treatment. In addition to presenting a general overview of methadone's role in treating opioid addiction, the volume also focuses on specific questions of current interest, particularly the critical issue of methadone maintenance in the prevention of AIDS. Public health specialists and policymakers will find this book an invaluable source of information about what can be expected from methadone maintenance programs and why such programs have achieved some success in the rehabilitation of opiate users, while so many other attempts in this area have failed.

Following an introductory chapter, the contributors look at the impact of AIDS epidemiology on methadone policy. The role of methadone in addressing intravenous drug abuse and unsafe sex practices in drug dependent persons is explored in an attempt to assess the ability of methadone maintenance programs to stem the spread of AIDS. Subsequent chapters review the world literature on methadone in treating opioid dependency, explore national policies and practices regarding methadone maintenance, present an international survey of methadone's role, and analyze the present state of research on methadone. A bibliography and index complete the volume.

Drs. John Herman and Max Hirshkowitz have assembled an expert panel of authors in the topic of Sleep and Psychiatry in Adults. Articles include: Sleep Deprivation and Circadian Disruption; Sleep Disturbances in Depression; Interventions for Sleep Disturbance in Bipolar Disorder; Sleep and Mood During Pregnancy and the Postpartum Period,Sleep Disturbances and Suicide Risk; Insomnia and Anxiety, Interconnectedness of Psychological Suymptoms, Personality Traits, and Sleep Disruption; Sleep in Schizophrenia; Post-traumatic Stress Disorder and Sleep; Benzodiazepine and Benzodiazepine Receptor Agonists for Insomnia and Anxiety; Non-benzodiazpine GABA A1 Receptor Agonists for Insonmia; CBT for Insomnia and Depression; Hypnosis for Insomnia in Patients with Depression and Anxiety; and Bright Light Therapy for Seasonal Affective Disorders.

This issue of Immunology and Allergy Clinics, devoted to Obesity and Asthma, is edited by Dr. Anurag Agrawal. Articles in this issue include: Clinical Implications of the Obese Asthma Phenotypes; Childhood Obesity and the Risk of Allergy; Metabolic Asthma: Is there a link between obesity, asthma, and diabetes?; Role of Weight Management in Obese-Asthma Control; Obesity and Airway Disease: A Bioenergetic Problem?; Nutrition, Obesity, and Asthma: Exploring Epigenetic Programming; Obesity and Asthma: The Role of Environmental Pollutants; Novel Therapeutic Strategies for Adult Obese Asthmatics; and From ADMA to Asthma.

This issue, edited by Dr. Babak Mokhlesi, features comprehensive discussion on the subject of Hypoventilation. Articles include: The History of Hypoventilation Syndromes; Pathophysiology of Hypoventilation During Sleep, Sleep Hypoventilation: Diagnostic Considerations and Technological Limitations; Advances in Positive Airway Pressure Treatment Modalities for Hypoventilation Syndromes; Scoring Abnormal Respiratory Events on Polysomnography During Noninvasive Ventilation; Obesity Hypoventilation Syndrome: Epidemiology and Diagnosis; Outcomes for Obese Patients with Chronic Respiratory Failure: Results from Observational and Randomized Controlled Trials; Non-PAP Treatment Modalities in Obesity-Hypoventilation Syndrome: Role of Exercise, Nonsurgical and Surgical Weight Reduction, Tracheostomy, Respiratory Stimulants, and Oxygen, and more!

Stimulant drugs are widely used in the treatment of ADHD in children and adults. Hundreds of studies over the past 60 years have demonstrated their effectiveness in improving attention span, increasing impulse control, and reducing hyperactivity and restlessness. Despite widespread interest in these compounds, however, their mechanisms of action in the central nervous system have remained poorly understood. Recent advances in the basic and clinical neurosciences now afford the possibility of elucidating these mechanisms. The current volume is the first to bring this expanding knowledge to bear on the central question of why and how stimulants exert their therapeutic effects. The result is a careful, comprehensive, and insightful integration of material by well-known scientists that significantly advances our understanding of stimulant effects and charts a course for future research. Part I presents a comprehensive description of the clinical features of ADHD and the clinical repsonse to stimulants. Part II details the cortical and subcortical neuroanatomy and functional neurophysiology of dopamine and norepinephrine systems with respect to the regulation of attention, arousal, activity, and impulse control on the basis of animal studies. Part III is devoted to clinical research, including recent studies of neuroimaging, genetics, pharmacodynamic and pharmacokinetic properties of stimulants, effects on cognitive functions, neurophysiological effects in humans with and without ADHD and in non-human primates, and comparison of stimulants and non-stimulants in the treatment of ADHD. Part IV is a masterful synthesis that presents alternative models of stimulant drug action and generates key hypotheses for continued research. The volume will be of keen interest to researchers and clinicians in psychiatry, psychology, and neurology, neuroscientists studying stimulants, and those persuing development of new drugs to treat ADHD.

As bariatric procedures become more commonplace, the safety and quality of bariatric surgery continues to rise. Risk factors remain inconsistent from hospital to hospital and procedure to procedure, however, highlighting the necessity for comprehensive education on the prevention and management of their resulting complications. In response to this need, Prevention and Management of Complications in Bariatric Surgery is the first book to compile the most up-to-date prevention and management strategies in this field. Edited by leading experts, it provides sound recommendations for collecting, monitoring, and analyzing outcomes, with an emphasis on quality and process improvement. Its scope is tremendously comprehensive, covering everything from common complications, such as leaks, bleeding, wound infections, and venous thromboembolism; to rare-but-deadly complications, such as Wernicke's encephalopathy and rhabdomyolsis as well as the emergency management of various life-threatening complications, including internal hernia, gastric nectrosis from banding, pulmonary embolus, and bleeding. Readers also learn about early-day, late-day, and intraoperative complications, for which the authors provide evidence-based recommendations for swift and accurate diagnosis, preventive strategies, and best practices in medical and surgical management. Comprehensive and accessible, this book is a valuable resource for bariatric surgeons and surgical trainees, physicians, and nurses who participate in the perioperative care of the bariatric patient.

This issue by Dr. Judith Owens focuses on sleep behavioral problems with articles covering topics such as Addressing Sleep Problems in Children with Anxiety Disorders, Behavioral Treatment of Insomnia in Children with Attention Deficit Hyperactivity Disorder (ADHD), Application of Cognitive Behavioral Therapy for Insomnia (CBT) in the Pediatric Population, Treatment of Delayed Sleep Phase Disorder (DSPD) in Adolescents, Tricks of the Trade: Practical Techniques for Managing Behavioral Sleep Problems in Young Children ,Quality of Life in Children with Narcolepsy, Myofunctional Therapy in the Treatment of Pediatric Sleep Disordered Breathing, Improving Positive Airway Pressure (PAP) Adherence in Children, Creating the "Child-Friendly" Sleep Lab, Controversies in Treatment of Pediatric Insomnia.

This book documents the history of ideas about problem gambling and its link to addictive disorders. The book uses a combination of literature review and conceptual and linguistic analysis to explore the way ideas about problem gambling gave changed over time. It examines the religious, socio-cultural, and medical influences on the development of the concept of problem gambling as a disease, along with the ways in which such ideas were influenced by attitudes about substance abuse. The history of mental illness, notably as it pertains to themes such as loss of control over behavior, is also addressed. The book ends with a discussion of the current status and future prospects, with an eye to which ideas about problem gambling and addictions seem most promising and which should perhaps be left behind.

Dr. Peter Gay has put together a team of expert authors centering on the topic of Central Sleep Apnea. Focus will include articles on CSA due to other Medical Disorders, Cheyne-Stokes Respiration, Central Sleep Apnea and Cardiovascular Disease, Complex Sleep Apnea, Adaptive servo-ventilation Treatment, Drug induced central apneas- Mechanism and Therapies, ICSD-2 and AASM Practice Parameters, Alternative approaches to treatment of Central Sleep Apnea, and Infant central apnea

Cell Press Reviews: Cancer Therapeutics informs, inspires, and connects cancer researchers at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publicatio offers a broad view of some of the most compelling topics in cancer therapeutics including: Genetic approaches for personal oncologyTargeting epigenetic dysregulation and protein interaction networksVaccines and antibodies in cancer immunotherapyTumor heterogeneity and chemotherapy resistanceTumor associated macrophages in anticancer treatment

Contributions come from leading voices in the field, including: - Daniel A. Haber, Director of Massachusetts General Hospital Cancer Center and Professor at Harvard Medical School - Tony Kouzarides, Professor at the University of Cambridge, Deputy Director of the Wellcome Trust/Cancer Research UK Gurdon Institute, and a founder of the cancer drug discovery company Chroma Therapeutics - Charles L. Sawyers, Chair of the Human Oncology and Pathogenesis Program at Memorial Sloan Kettering Cancer Center, President of the American Association for Cancer Research, member of the presidentially appointed National Cancer Advisory Board, and recipient of the 2013 Breakthrough Prize in Life Sciences

Cell Press Reviews: Cancer Therapeutics is part of the Cell Press Reviewsseries, which features reviews published in "Cell Press" primary research and "Trends" reviews journals.
Provides timely, comprehensive articles on a wide range of topics in cancer therapeutics
Offers insight from experts on genetic, molecular, and cellular aspects of cancer therapy
Features reviews on basic science advances translated into drug discovery and therapeutic approaches
Includes articles originally published in "Cell, Cancer Cell, Trends in Genetics, Trends in Molecular Medicine," and "Trends in Pharmacological Sciences""

This issue of Sleep Medicine Clinics will be Guest Edited by Jim Barker, MD CPE, FACP, FCCP, FAASM Shirley Fong Jones, MD, FCCP of Scott and White Memorial Hospital and will focus on Obstructive Sleep Apnea. Article topics include Weight loss, Pharmacologic therapy of obstructive sleep apnea, Alternative Therapies, Masks and Interfaces, Outcomes of treatment of hypersomnia for OSA, Effects of therapy on CV outcomes, Complex Sleep Apnea, Oral appliances, Cost of therapy, Medicolegal aspects of treatment, Residual sleepiness, Therapy and Metabolic Outcomes, and Therapies for Children with OSA.

Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. "The Effects of Drug Abuse on the Human Nervous System "presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers.
*A comprehensive reference on the effects of drug addiction on the human nervous system
*Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs
*Includes foundational science chapters on the biology of addiction
*Details challenges in diagnosis and treatment options

This issue of Nursing Clinics of North America is Guest Edited by Al Rundio, RN, at Drexel University and will focus on Addictions. Article topics will include Office-Based Opioid Treatment, Addictions and Pregnancy, Peer Assistance, Relapse Prevention for Addictions, Adolescents and Addiction, Use of Photo Voice in Addictions, Health Promotion and Prevention Strategies, Maintaining Sobriety and Recovery, and SBIRT (Screening Brief Interventio and Treatment.)

Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. "Neurobiology of Alcohol Dependence "highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence.
Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependenceChapters authored by leaders in the field around the globe the broadest, most expert coverage available"

The most important writings on the psychoanalytic understandings and treatments of drug and vice addiction Drug abuse, alcoholism, compulsive gambling, and other destructive addictions plague our society. Theories of addiction locate its cause variously-in factors related to the substance, the addict's personality, or to the addict's environment. Arguments about effective treatment programs are fierce. Essential Papers on Addiction presents the most important writing and the various sides of the debate on the psychoanalytic understanding and treatment of addiction. Daniel Yalisove outlines the history of the treatment of addiction and introduces important psychoanalytic concepts used in understanding addicts. The book includes case studies which illustrate the course of addiction and presents the work of the most influential theorists in the field. Divided into eight sections focusing on historical work on addiction, psychoanalytic theories of addiction, transference and countertransference issues in treating addiction, psychoanalytic treatment for the addictions, psychoanalytic therapy and disease concepts, and psychiatric illness and addiction, this definitive volume includes contributions by the most experienced and renowned experts on the subject. Contributors include S. Freud, E. Glover, S. Rado, R. P. Knight, L. Wurmser, N. E. Zinberg, H. Krystal, D. Jacobs, R. Fine, J. Gustafson, C. L. Brown, M. L. Selzer, V. Davidson, J. Imhof, R. Hirsch, R. E. Terenzi, M. E. Chafetz, A. Silber, R. J. Rosenthal, E. M. Pattison, M. B. Sobell, L. C. Sobell, J. E. Zweben, E. Simmel, B. Brickman, E. J. Khantzian, R. D. Weiss, S. M. Mirin, A. T. McLellan, and H. J. Richards.

"Keane's work is thoughtful and thought provoking and incorporates elements of medical history and philosophy."--"Psychiatric Services"

"A theoretically engaging exploration of the arbitrariness of the field of addiction studies."
--Robert Granfield, co-author of "Coming Clean"

We assume that there is something wrong with addiction. But how exactly is it bad to be an addict? What's Wrong with Addiction? explores the ways in which our views of addiction categorize certain ways of being as unnatural, diseased, and self-destructive, often working to reinforce existing social hierarchies. Under the rubric of addiction, pleasure and desire are demonized, while the addict is viewed as damaged and in need of physical and moral rectificaiton.

Keane examines the ambiguities in medical science's quest to construct addiction in chemical and biological terms, revealing the strains in the oppositions between disease and health, and addiction and normality. She demonstrates how these strains have become more insistent as the net of addiction has spread wider, moving beyond chemical substances to other problems of consumption and conduct such as compulsive eating and sex addiction. The book also critically examines the ideals of health, freedom, and happiness found in popular self-help literature, suggesting that it is the practices of self-surveillance and self-interrogation promoted in recovery guides which actually produce the inner self as an object of concern.

Why is music so important to most of us? How does music help us both in our everyday lives, and in the more specialist context of music therapy? This book suggests a new way of approaching these topical questions, drawing from Ansdell's long experience as a music therapist, and from the latest thinking on music in everyday life. Vibrant and moving examples from music therapy situations are twinned with the stories of 'ordinary' people who describe how music helps them within their everyday lives. Together this complementary material leads Ansdell to present a new interdisciplinary framework showing how musical experiences can help all of us build and negotiate identities, make intimate non-verbal relationships, belong together in community, and find moments of transcendence and meaning. How Music Helps is not just a book about music therapy. It has the more ambitious aim to promote (from a music therapist's perspective) a better understanding of 'music and change' in our personal and social life. Ansdell's theoretical synthesis links the tradition of Nordoff-Robbins music therapy and its recent developments in Community Music Therapy to contemporary music sociology and music studies. This book will be relevant to practitioners, academics, and researchers looking for a broad-based theoretical perspective to guide further study and policy in music, well-being, and health.