Digital Therapeutics for Mental Health and Addiction: The State of the Science and Vision for the Future presents the foundations of digital therapeutics with a broad audience in mind, ranging from bioengineers and computer scientists to those in psychology, psychiatry and social work. Sections cover cutting-edge advancements in the field, offering advice on how to successfully implement digital therapeutics. Readers will find sections on evidence for direct-to-consumer standalone digital therapeutics, the efficacy of integrating digital treatments within traditional healthcare settings, and recent innovations currently transforming the field of digital therapeutics towards experiences which are more personalized, adaptable and engaging. This book gives a view on current limitations of the technology, ideas for problem-solving the challenges of designing this technology, and a perspective on future research directions. For all readers, the content on cultural, legal and ethical dimensions of digital mental health will be useful.

This volume takes a fresh look at the problems of designing effective and humane service care delivery systems for the seriously mentally ill. The author addresses a number of major themes, including the differing definitions of mental illness and the differing treatment technologies that have logically developed from them, the varying theories regarding the structure and design of the service delivery system, and the policy dilemmas that lead to inconsistent and inequitable treatment. Demonstrating that there are wide areas of agreement among the disputing professionals. Chandler offers guidelines for finding these zones of agreement and achieving a consensus for realistically improving the system of care. The focus throughout is on the development of practical problem-solving strategies for professionals, advocates, patients, and their families. A particularly valuable feature is the inclusion of an in- depth case study that demonstrates the application of effective conflict resolution techniques in the mental health setting.

Following an introductory overview of the persistent problems of people with mental illnesses, Chandler analyzes the recurring themes and issues that have surrounded the mental health field since its earliest conception. She goes on to examine such issues as the failure of the deinstitutionalization policies for the seriously and persistently mentally ill and the changing roles and responsibilities of state and local governments, families, mental health providers, and welfare agencies. The remaining chapters explore the nature of advocacy in the mental health field. Chandler describes the framework and belief structures of prominent advocacy organizations, discusses the advocacy wars among the organizations and agencies whose goal it is to help the mentally ill, and delineates a negotiation strategy for meeting the needs of the mentally ill. Topics such as the rise of the National Alliance for the Mentally Ill, the growth of patient rights groups, and strategies for altering the definitions of mental illness receive extended treatment. In the final chapter, Chandler outlines the knowledge necessary to understand the complex issues surrounding the mentally ill and the skills necessary to work successfully in this field.

This wide-ranging survey of the state of the art in clinical pragmatics includes an examination of pragmatic disorders in previously neglected populations such as juvenile offenders, children and adults with emotional and behavioural disorders, and adults with non-Alzheimer dementias. This book makes a significant contribution to the discussion of pragmatic disorders by exploring topics which have a fast-rising profile in the field. These topics include disorders in which there are both pragmatic and cognitive components, and studies of the complex impacts of pragmatic disorders such as mental health problems, educational disadvantage and social exclusion. This book also presents a critical evaluation of our current state of knowledge of pragmatic disorders. The author focuses on the lack of integration between theoretical and clinical branches of pragmatics and argues that the work of clinicians is all too often inadequately informed by theoretical frameworks. She attempts to bridge these gaps by pursuing a closer alliance of clinical and theoretical branches of pragmatics. It is claimed that this alliance represents the most promising route for the future development of the field. At once a yardstick measuring progress thus far in clinical pragmatics, and also a roadmap for future research development, this single-author volume defines where we have reached in the field, as well as where we have to go next.

The book aims to review knowledge on the disorders of eating behaviour and body composition in some of the non-primate higher animals and to relate these to similar conditions in humans. With advances in understanding the nature of these disorders and their biological basis, it seems timely to assess what cross-species comparisons can tell us about the general underlying factors at work. This may also help to delineate what may be a general biological basis that humans share with their higher animal comrade species and what may distinguish human from non-human, particularly in a cultural context. This could help in combating better the problems of these conditions in the animal species as well as in man and in suggesting well-based preventive measures. As far as people are concerned the last two decades of the 20th century have shown a significant increase in obesity in the richer countries, particularly the USA (Table 1). Possibly associated with the obesity boom, there is an increasing awareness of other disorders of eating behaviour and body composition. These range from anorexia nervosa, at the other end of body composition to obesity, to others, such as bulimia, with more variable effects on body composition.

* Includes chapters on sleep phase disorders, sleep apnea, periodic limb movements, narcolepsy, limit setting disorders in children, enuresis, and night terrors.
* Provides a unique, behavioral approach to sleep medicine.

Phototherapy exemplifies scientific medicine. The major advances have resulted from effective collaborations between basic researchers and clinicians. This book is directed to clinicians and basic researchers who are interested in current and emerging implementations of phototherapy. It can serve as an introductory reference and a textbook for advanced undergraduate and graduate courses in medical physics and biomedical engineering. The emphasis is on the science underlying the various phototherapy procedures, which encompasses aspects of classical and molecular photophysics, biological photochemistry, photobiology and biophotonics. Topics that do not usually appear in other general sources include the theory and applications of tissue optics, Monte Carlo simulation, light dosimetry, and analytical modeling of laser surgery. Many illustrative problems with answers are provided to exemplify the more quantitative aspects of each topic.

Different from a textbook or academic journal, the File represents a collection of explicit descriptions about therapy interventions written by practitioners themselves. The description of the rationale for the therapy, the intervention itself and evaluation of outcomes are of paramount importance. Each contributor guides the reader through the thinking that they engaged in as they decided what to do, often with considerable frankness about the difficulties involved.
The File will be of equal value to experienced practitioners and students alike.

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While citizens experiment with illegal drugs, their governments experiment with regulations to prohibit drugs. Scholars, analysts, and policy makers who know what legal prohibitions other countries have tried and found successful will have a better chance of crafting effective drug policy for their countries. This special issue of "The Annals" describes the experiences of eleven countries: Australia, Canada, Columbia, Denmark, France, Iran, Jamaica, Mexico, Portugal, Russia, and Sweden. Articles are grouped by geography and wealth: the wealthy West, the western hemisphere, and the transition countries.

The drug problems of wealthy Western nations have generally worsened since the 1960s. Some have no clearly articulated vision behind their drug policy (e.g. Denmark); others have tough policies (e.g. Sweden). France and Portugal both recently instituted sharp changes in drug policy. While no outcome results are yet available from Portugal, France has experience a huge increase in the number of users in treatment. Australia s strong harm-reduction policy remains in place despite increasing heroin deaths and other drug-related problems.

U.S. consumption and U.S. international drug policies affect western hemisphere countries policy as well as generate problems for them. Although Mexican drug use remains at modest levels, the country faces violent and powerful criminal groups. The groups creation is related to Mexico s role as the principal source and primary transshipment route for drugs bound for the U.S. IN Jamaica, another route for cocaine shipped to the U.S. and another focus of U.S. international drug policy, drug trafficking has exacerbated the long-standing problem of politically related gang violence by increasing the moneys and weapons involved. Drug use is a relatively minor concern of Columbian policy, also under U.S. pressure; instead, it focuses on trafficking and related corruption and violence.

Iran and Russia are countries in transition. Contending with fundamental economic and social change following the collapse of the Soviet Union, Russia has had little political debate regarding its highly intolerant drug policy. Iran s drug policies have frequently shifted during its long history of dealing with opiate abuse, from harsh punishment to regulation of use and back again. Most recently, more therapeutically oriented approaches have been tried.

Two articles address geographically broader issues. One shows how U.S. politicians distorted results from a study of needle exchange in Vancouver. The other discusses creation of a new regulatory regime for governing developed nations banking systems, in the belief that illegal drugs account for a substantial fraction of suspicious financial transactions, particularly across national borders. "

This book uniquely combines cutting-edge medical, psychological, and sociocultural topics pertinent to eating disorders. In the medical realm, the book focuses on Eating Disorders' newly investigated associations with ADHD and sleep disorders, and on innovative treatments of osteoporosis in anorexia nervosa. Novel contributions in the psychological realm address families' trans-generational transmission of Eating Disorders-related difficulties and novel internet-based treatments for such families. Lastly, in the sociocultural realm, the book discusses social contagion and Pro-Ana websites as increasing risk for disordered eating in young women around the globe. This volume provides readers with more holistic perspectives of each realm and their interplay, to promote Eating Disorders' understanding, treatment, prevention, and research. It provides various professionals including mental health providers, physicians, nutritionists, and graduate students in these professions.

There are very few books available which are concerned with the unique communication problems that can come with traumatic brain injury (TBI). In recent years there has emerged a realisation that these difficulties in communication are closely tied to the cognitive, behavioural and social problems observed following traumatic brain injury. This is changing the way people with TBI are assessed and is generating new approaches to rehabilitation.
This volume will be of interest to psychologists, speech pathologists and therapists and linguists. Clinicians and researchers working with people with traumatic brain injury, and their students, will find it a comprehensive source of contemporary approaches to characterising the communication problems of people with TBI and for planning rehabilitation.

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Phytochemicals are components acting individually, additively or synergistically, usually as a component of whole food, that have the characteristics of providing protective, preventative and possibly curative roles in the pathogenesis of cancer and other chronic disease progressions. Nutraceutical is a term used to describe beneficial phytochemicals. The mechanisms of action of nutraceuticals may be one of several. Free radical scavenger and antioxidant nutraceuticals can nullify damage by any number of biochemical mechanisms, but some also exert benefit by enhancing immune function.

A conservative economic analysis was done in 1993 of solely hospital care costs and the roles that three nutrient antioxidants could exert on cardiovascular disease, breast cancer and cataracts. The study considered the potential impact of only three antioxidants, vitamins C and E, and beta-carotene, and the possible annual savings in hospital care costs alone, which could exceed 8 billion dollars. Expert public health physicians believe that as much as 700f disease is preventable.

The chapters in this book were organized to reveal existing and emerging knowledge of nutraceuticals found in garlic, soy and licorice. Lead chapters discuss the epidemiological evidence, and following chapters discuss chemical or biochemical evidence at the cellular level, as well as the presentation of some clinical data.

A major conclusion of the overall effort is that the science of nutraceuticals is very incomplete, but that findings to date have great promise.

This book represents the first serious attempt to explain the fundamental basis of ozonetherapy and is a relevant step towards achieving further progress. Ozone is now considered a real drug and, after reacting with body fluids, releases messengers and activates several mechanisms which are able to elicit multiple biological effects. The therapeutic window has been defined and, contrary to the dogma that ozone is toxic any way you deal with it', it has been shown that ozone toxicity can be tamed and even totally avoided.

New powerful methodologies have been devised and astonishing clinical results in vascular and infectious diseases have already been achieved. An exciting novelty is the induction of an adaptive response that implies the unsuspected possibility of arresting cell degeneration due to endogenous chronic oxidative stress. However, further basic and controlled clinical studies need to be performed to fully exploit ozone's therapeutic potentials and to establish the real validity of this therapy. Authoritative scientists and clinicians should abandon their prejudice and consider the profound difference between endogenous oxidative stress and the new concept of ozonetherapeutic shock'. If this happens, we could soon have a simple and inexpensive tool to restore health in millions of patients.

This book has been written in a plain scientific language and can be read by scientists and clinicians, as well as by patients keen on regaining a state of well being.

This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs.
* The revised fourth edition contains approximately 50% new material
* Includes information on all the latest drugs

Most people who block and stammer do not do so every time they speak Indeed, most people who stammer are consistently fluent in certain contexts. When by themselves, speaking to a pet or speaking to a person with whom they are comfortable they speak fluently. This behaviour has been a puzzle for people who stammer and for speech pathologists who think stammering is a purely physical problem for many years. Now the puzzle has finally been solved by this outstanding new book which details a completely new approach to treating this debilitating condition. Bob Bodenhamer explains that blocking results from the thinking (cognition) of the stammerer as he or she associates speaking with a lot of fear and anxiety about stammering. Most blocking is no more than a panic attack expressed in the muscles that control breathing and speaking. This book both explains the structure of blocking and provides the tools for gaining more fluency. Bob G Bodenhamer's related paperback title I Have a Voice: How to stop stuttering, 16.99.

This is a practical handbook, whichwill provide an everyday reference for the inexperienced to provide artificial nutrition in a safe and effective manner. Total Parenteral Nutrition (TPN) is a means of providing nutrients to patients whom, for whatever reason, are unable to take food orally This book covers the whole range of factors involved in TPN, patient selection and suitability for TPN, contraindications to patients receiving TPN and the practicalities involved such as line selection. It examines the range of treatment options available that are alternatives to TPN. It is also a unique publication in that it considers the patients opinion, body image and lifestyle. Despite its broad coverage, the book is able to explain new techniques concisely, which will help readers professional development and increase their confidence in using these techniques.The books elementary nature makes it ideal for nurses or junior medical staff who are unfamiliar with this therapy or who lack knowledge about central venous catheters. Appendix contains step by step procedures referred to throughout the book that can be adapted by the reader to develop new local protocols.The book is illustrated with anatomical drawings and drawings of catheters which will give the reader a clearer understanding of aspects of TPN treatment. Focuses on the multidisciplinary team involved in TPN patient care i.e. pharmacists and dieticians. The editor is recognised and well respected in this field and has already published work in journals.

Why are young women today deeply unhappy with their own bodies? Why do even young girls inflict serious harm to themselves by dangerous patterns of bingeing and dieting? Drawing on a wide source of feminist perspectives this book examines this epidemic of body-hatred.

This comprehensive book pulls together the essential elements needed to assess sleep apnea patients for the transoral robotic surgical approach and how to optimize the surgery. Detailed information on patient selection, pre-operative work up, anesthesiological pre and post-operative management, surgery, complication prevention and management is provided along with background on sleep medicine and sleep surgery. Authored for ENT surgeons, head and neck specialists and neurologists, pneumonologists, sleep doctors as well for anesthesiologists, chapters offer solutions pulled from experts in the field of sleep surgery and information relevant to geographic areas worldwide.

Expanding Receptive and Expressive Skills through Stories (EXPRESS): Language Formulation in Children with Selective Mutism and Other Communication Needs is a resource that provides a specific treatment approach for professional speech-language pathologists working with children with selective mutism and other language delays or disorders including language learning disabilities, autism spectrum disorders, or for children learning English as a second language. It is a program for expanding receptive and expressive language skills at varying stages of language development, with five levels of communication to allow the clinician to start at the appropriate level for each child, and progress through the levels.The "EXPRESS" approach includes activity modules corresponding to classic children's stories. Children's literature is used as a tool for presenting activities designed to help children learn specific language skills, and supports the Common Core State Standards. Each of the modules requires the corresponding storybook that can be obtained individually or found within "The 20th Century Children's Book Treasury", a compendium that includes all the stories.Using "EXPRESS", children listen to the stories and through the activities presented acquire key concepts, ideas, and details about the material. Vocabulary is enhanced through drawing, describing, and demonstration. Children also have an opportunity to make inferences from the textual material through the question-answer routines developed for each story. Creativity and imagination are fostered using sentence formulation and story generation. "EXPRESS" also includes forms to help the clinician monitor progress and a PluralPlus companion website with video links to the stories and downloadable items from the book such as activity cards and scoring sheets.

Handbook of Animal Models of Infection is a complete revision of a three-volume text that was published in 1986. It incorporates the major advances in the field during the past decade, in particular those concerning molecular biological procedures and new models that have been developed. It focuses on both methods and techniques, which makes it an essential and comprehensive reference as well as a benchtop manual. The Handbook will help investigators save time and effort in formulating an approach to test a new potential therapeutic agent or combination of agents for "in vivo" efficacy and to position the therapy for specific infections where it may have therapeutic promise. The book is divided into five sections; the first covering the general methodologies, followed by sections describing experimental bacterial, mycotic, parasitic, and viral infections.
Key Features
* Discusses ethical and safety aspects in an introductory background section
* Covers principles of animal care and current techniques appropriate for the use of animal models of infection
* Details a wide range of animals including rodents, rabbits, cats, and primates
* Provides hands-on descriptions of how to set up the model
* Discusses the major advantages and limitations of each model
* Ensures full coverage of bacterial, fungal, viral, and parasitic infections

The ability to communicate is amazing. No other human ability is so complicated, so sophisticated, so important to civilization-and yet so taken for granted. How tragic would life be without the marvelous ability to communicate? In "Simply Amazing: Communication Sciences and Disorders," Dr. Dennis C. Tanner explores the stages of the communication chain and examines the act of speech communication from the speaker's thoughts to the listener's understanding of them.

Relying on more than forty years of experience studying, teaching, researching, and providing clinical services in the communication sciences discipline, Tanner provides a frank and informative discussion about the subject, including both conventional and offbeat theories of human communication, unique and sometimes bizarre disorders, and intriguing patients.

Through anecdotes, examples, illustrations, case studies, and personal asides of the amazing human ability to communicate-as well as the myriad disorders, defects, delays, and disabilities that can lay waste to it-"Simply Amazing: Communication Sciences and Disorders" provides keen insight into the world of communication.

Compulsive buying is a serious, often secretive affliction, with profound emotional, social, occupational, and financial consequences. As many as a quarter of us have problems with buying, and studies suggest that between one and six percent of the population are full-fledged compulsive buyers. I Shop, Therefore I Am: Compulsive Buying and the Search for Self brings together, for the first time, the most important thinking about this disorder. As more and more therapists encounter compulsive buying (whether as a presenting problem or revealed in the course of ongoing therapy), the need for an in-depth clinical understanding of the disorder has grown. Dr. Benson has responded admirably to that need with a practical, comprehensive, and wonderfully readable work. While the book focuses a wide-angled lens on the many aspects of compulsive buying, it emphasizes understanding the disorder as a desperate search for self in people whose identity is not securely established. It defines the syndrome of compulsive consumption, examines the range and variations within it, discusses assessment and associated disorders, and delineates successful treatment modalities. Offering insights from a broad spectrum of therapies psychopharmacology, psychodynamic therapy, cognitive-behavioral treatment, couples and group therapy, self-help, and financial counseling this book is an indispensable toolbox for the increasing number of therapists who see patients with shopping, buying, or debting problems. A Jason Aronson Book"

Neuronal Nicotinic Receptors: Pharmacology and Therapeutic Opportunities
Edited by Stephen P. Arneric and Jorge D. Brioni
Nicotine's efficacy in the treatment of pain and anxiolysis, and its usefulness as a memory enhancer, have been suspected for many years, but research into the molecular biology of nicotinic acetylcholine receptors (nAChRs) traditionally has focused on smoking cessation. Now, thanks to recent technological advances in the molecular biology and electrophysiology of nAChRs, an abundance of evidence has emerged in support of nAChR ligands in the treatment of a range of CNS disorders, including Alzheimer's disease, Parkinson's disease, neuropathic pain, attention deficit disorder, and depression.
Featuring contributions from an international team of experts in the field, this volume provides researchers and clinicians with a comprehensive review of nAChRs, their molecular biology, pharmacology, and clinical implications. Moving from the molecular to the clinical levels, the authors explore the latest developments in all areas of nAChR research, including:
* Molecular biology and biochemistry of nAChRs
* The physiological roles of nAChRs
* Pharmacokinetics of nicotine-like alkaloids
* Recent breakthroughs and emerging trends in nAChR medicinal chemistry
* Current and emerging therapeutic applications of novel nAChR ligands.

A timely, authoritative review of basic research into nAChRs and their role in the development of new therapeutic strategies in the treatment of a range of various CNS diseases, Neuronal Nicotinic Receptors: Pharmacology and Therapeutic Opportunities is required reading for neuroscientists, pharmacologists, medicinal chemists, biological psychiatrists, and psychopharmacologists.