The recovered possess the key to overcoming anorexia. Although individual sufferers do not know how the affliction takes hold, piecing their stories together reveals two accidental afflictions. One is that activity disorders-dieting, exercising, healthy eating-start as virtuous practices, but become addictive obsessions. The other affliction is a developmental disorder, which also starts with the virtuous-those eager for challenge and change. But these overachievers who seek self-improvement get a distorted life instead. Knowing anorexia from inside, the recovered offer two watchwords on helping those who suffer. One is "negotiate," to encourage compromise, which can aid recovery where coercion fails. The other is "balance," for the ill to pursue mind-with-body activities to defuse mind-over-body battles.

1. Metabolism of Ethanol.- 1.1. Pathways of Ethanol Oxidation.- 1.2. Alteration in the Metabolism of Ethanol after Chronic Ethanol Consumption.- 1.3. Effects of Liver Disease, Blood Flow, Circadian Rhythm, Gender, and Other Factors on Hepatic Alcohol Metabolism.- 1.4. Effects of Other Drugs on Ethanol Metabolism.- 1.5. Ethnic and Genetic Factors in Ethanol Metabolism.- 1.6. Extrahepatic Ethanol Metabolism.- 1.7. Summary.- References.- 2. Acetaldehyde and Acetate.- 2.1. Pathways of Acetaldehyde and Acetate Metabolism.- 2.2. Effect of Chronic Ethanol Consumption on Acetaldehyde and Acetate Metabolism.- 2.3. Effect of Liver Injury on Acetaldehyde Metabolism.- 2.4. Effects Attributable to Acetaldehyde and Acetate after Acute and Chronic Ethanol Consumption.- 2.5. Summary.- References.- 3. Alcohol, Hormones, and Metabolism.- 3.1. Hypothalamic-Pituitary-Thyroidal Axis.- 3.2. Parathormone and Calcitonin.- 3.3. Adrenocortical Function: Glucocorticoid Secretion.- 3.4. Adrenocortical Function: Mineralocorticoid Secretion.- 3.5. Adrenal Medullary Function.- 3.6. Growth Hormone.- 3.7. Antidiuretic Hormone and Oxytocin.- 3.8. Pancreatic and Gastrointestinal Hormones.- 3.9. Alteration of Carbohydrate Metabolism by Alcohol.- 3.10. Effects of Ethanol on Ketone Metabolism.- 3.11. Alcoholic Ketoacidosis.- 3.12. Hyperlactacidemia and Lactic Acidosis.- 3.13. Alcoholic Hyperuricemia and Its Relationship to Gouty Attacks.- References.- 4. Ethanol and Lipid Disorders, Including Fatty Liver, Hyperlipemia, and Atherosclerosis.- 4.1. Interaction of the Metabolism of Ethanol and Lipids.- 4.2. Pathogenesis of the Alcoholic Fatty Liver.- 4.3. Agents and Procedures that Prevent the Alcoholic Fatty Liver.- 4.4. Effects of Ethanol on Blood Lipids: Characteristics and Pathogenesis of Alcoholic Hyperlipemia.- 4.5. Ethanol, Atherosclerosis, and High-Density Lipoproteins.- 4.6. Interaction of Ethanol with Vascular Prostacyclin Production.- 4.7. Summary.- References.- 5. Effects of Ethanol on Amino Acid and Protein Metabolism.- 5.1. Effects of Ethanol on Nitrogen Balance and Body Protein Composition.- 5.2. Effects of Ethanol on Amino Acids.- 5.3. Effects of Ethanol on Hepatic Protein Synthesis.- 5.4. Effects of Ethanol on Hepatic Protein Secretion.- 5.5. Effects of Ethanol on Hepatic Protein Catabolism.- 5.6. Hepatic Accumulation of Protein after Chronic Ethanol Feeding.- 5.7. Dietary Requirements for Protein in the Alcoholic.- 5.8. Summary.- References.- 6. Interaction of Ethanol with Other Drugs.- 6.1. Interaction with Drug Absorption.- 6.2. Interaction with Plasma Protein Binding.- 6.3. Interaction with Hepatic Blood Flow.- 6.4. Interaction with Hepatic Cell Uptake.- 6.5. Interaction with Hepatic Metabolism.- 6.6. Pharmacological Interactions.- 6.7. Summary and Therapeutic Guidelines.- References.- 7. Alcohol and the Liver.- 7.1. Epidemiology of Alcoholic Liver Disease.- 7.2. Pathology and Symptomatology of the Various Stages of Alcoholic Liver Injury.- 7.3. Pathogenesis of Alcoholic Liver Injury.- 7.4. Diagnosis of Alcoholic Liver Injury.- 7.5. Prognosis and Treatment of Alcholic Liver Injury.- References.- 8. Alcohol and the Hematologic System.- 8.1. Red Cells.- 8.2. Platelets.- 8.3. Granulocytes.- 8.4. Monocytes and Macrophages.- 8.5. Lymphocytes.- 8.6. Other Factors Favoring Infection.- 8.7. Summary.- References.- 9. Immunologic Reactions in Alcoholic Liver Disease.- 9.1. Morphological Considerations.- 9.2. Genetic Factors.- 9.3. Immunoglobulins, Antibodies, and Immune Complexes.- 9.4. Hepatitis B Virus (HBV).- 9.5. Hepatitis C Virus (HCV).- 9.6. Serum Factors and Cytokine Activity.- 9.7. Cell-Mediated Alterations.- 9.8. Abnormal Antigen Expression on Liver Cells.- 9.9. Alcohol and Alteration of the Immune Response in Alcoholics without ALD.- 9.10. Summary.- References.- 10. Alcohol and the Digestive Tract.- 10.1. Introduction.- 10.2. Oropharynx and Salivary Glands.- 10.3. Esophagus.- 10.4. Stomach.- 10.5. Effect of Alcohol on the Small Intestine.- 10.6...

RESEARCH FINDINGS: Drugs in the Workplace: Extent and Impact of Alcohol and Drug Usage/Problems in the Workplace/Workforce (J. Martin). Predictors of Drug Use and Implications for the Workplace (M. Newcomb). Drug Testing Programs: Drug Testing Methods and Interpretation of Results (B. Kapur). The Impact and Effectiveness of Drug Testing Programs in the Workplace (S. Macdonald). Legal Issues: Some Legal Aspects of Drug Testing in the Canadian Workplace (M. Pinsonneault). Constitutional and Statuatory Treatment of Drug Testing in the United States (R.L. Lieberwitz). Other Workplace Programs: Behavioral Tests to Assess Performance (B. Butler). Alternatives to Drug Testing (M. Shain). PERSPECTIVES ON DRUG TESTING: Unions' Perspective on Workplace Drug Testing (S. Alvi). Drug Testing, the War on Drugs, Workers, and the Workplace (J. Blackwell). 5 additional articles. Index.

This work will provide readers with uniquely systematic coverage of the field of speech and language pathology. Taking as its starting point the highly successful "Encyclopedia of Language and Linguistics," the book comprises selected updates from the original work combined with a high proportion of newly commissioned material which together give a comprehensive overview of the state of the art in speech and language pathology. The work is the most up-to-date and detailed reference available in this field.
The book addresses all main aspects related to speech and language comprehension and production, both in children and in normal adults. It also presents in a systematic way disorders of speech and language due to developmental and acquired causes, the most common forms of treatment and their degree of efficacy.

"Perioperative Addiction" addresses an issue that every anesthesiologist will encounter many times during the course of his or her career: the patient who arrives for operative care under the influence of legal or illegal drugs. The editors and contributors provide expert guidance on how to identify and manage the addicted patient, approaching the subject from the vantage points of the specific drug and of special patient populations.

Features:

Guidance for spotting and managing addicted patients

All common and important drugs of addiction, from opioids, cocaine, club drugs, and alcohol, to tobacco, marijuana, nitrous oxide, inhalants, and propofol

Special populations, including pregnant women, pain patients, adolescents, older patients, and healthcare professionals

Fascinating overview of the long history of addiction

Genetic basis of addiction, and the range of pharmacological treatments for addiction

One of the few books on the topic, this updated edition offers alternatives to disease models of addiction by exploring personal pathways to recovery. Focusing on alcohol and drug problems, it provides a literature review of 40 years of studies on self-change with particular emphasis on the current decade and methodological issues (starting with how much or how little treatment constitutes "treatment"). The 24 experts keep the coverage consistently readable, and dozens of brief narratives from individuals who have successfully recovered from an addictive behavior without formal help lend valuable personal perspectives.

Get high. Become addicted. Commit crimes. Get arrested and be sent to jail. Get released. Repeat. It's a cycle often destined to persist, in large part because the critical step that is often missing in the process, which is treatment geared toward ensuring that addicts are able to reenter society without the constant threat of imminent relapse. The Handbook of Evidence-Based Substance Abuse Treatment in Criminal Justice Settings probes the efficacy of corrections-based drug interventions, particularly behavioral treatment. With straightforward interpretation of data that reveals what works, what doesn't, and what needs further study, this volume navigates readers through the criminal justice system, the history of drug treatment for offenders, and the practical problems of program design and implementation. Probation and parole issues as well as concerns specific to special populations such as women, juvenile offenders, and inmates living with HIV/AIDS are also examined in detail. The Handbook's wide-ranging coverage includes: * Biology and genetics of the addicted brain. * Case management for substance-abusing offenders. * Integrated treatment for drug abuse and mental illness. * Evidence-based responses to impaired driving. * Monitoring technology and alternatives to incarceration. * The use of pharmacotherapy in rehabilitation. This must-have reference work is a comprehensive and timely resource for clinicians, researchers, and graduate students across a variety of disciplines including clinical psychology, criminology and criminal justice, counseling, and educational policy makers.

Covers all aspects of CTS: diagnosis - management - outcome assessment

Abundantly illustrated

This book takes a novel approach to the study of male eating disorders - an area that is often dominated by clinical discourses. The study of eating disorders in men has purportedly suffered from a lack of dedicated attention to personal and socio-cultural aspects. Delderfield tackles this deficiency by spotlighting a set of personal accounts written by a group of men who have experiences of disordered eating. The text presents critical interpretations that aim to situate these experiences in the social and cultural context in which these disorders occur. This discursive work is underpinned by an eclectic scholarly engagement with social psychology and sociology literature around masculinities, embodiment and fatness, belonging, punishment, stigma, and control; leading to understandings about relationships with food, body and self. This is undertaken with a reflexive element, as the personal intersects with the professional. This text will appeal to students, scholars and clinicians in social sciences, humanities, and healthcare studies, including public health.

In just under three decades, the world has witnessed an enormous rise in obesity with a parallel growth in cardiometabolic disease risk factors characterized by insulin resistance, dyslipidemia, and hypertension, together known as the metabolic syndrome - conditions previously unheard of in children and adolescents. During this time, we have little knowledge of the global and cumulative detrimental health effects of childhood obesity. As obese children age, not only will their health be negatively affected, but infertility and pregnancy complications associated with the metabolic syndrome will affect generations to come. The work force will undoubtedly be affected because of increased sick days and decreased work productivity. Identifying children and adolescents at the earliest stages of chronic disease onset should be the goal of clinical practice, yet there is no clear guidance for defining the risk of metabolic syndrome or appropriate risk-factor thresholds in these groups. If children are identified early in the disease process, lifestyle and clinical interventions can be instituted when they are potentially more effective. Pediatric Metabolic Syndrome: Comprehensive Clinical Review and Related Health Issues approaches the pediatric metabolic syndrome by elucidating its effects on specific organ systems and by considering the problem through understanding the social, psychological and economic consequences of it. The Editors have recruited an invited group of esteemed experts in the field to provide the most timely and informative approaches on how to deal with this health crisis. Through educating our practitioners, our future researchers, our health and community organizations, our legislators and our families and children, we have the best chance at improving the health trajectory of the next generation.

A psychiatrist examines how the world's four most important mind-altering substances- alcohol, cocaine, nicotine, and opiates-have played a significant role throughout human history, and explains how these powerful drugs affect the brain and cause addiction. Alcohol, cocaine, nicotine, and opiates have spurred some of the greatest human pleasure and pain across time. Providing information that ranges as widely as from ancient Egypt to modern times, this book comprehensively addresses the good, the bad, and the very ugliest aspects of these substances, examining their history, their effects on the brain and body, and on civilization itself. Frances R. Frankenburg, MD, employs accessible, everyday language to explain the neurology of addiction and describe how these "brain-robbing" substances work to hijack the brain's pleasure systems to create powerful addictions. The author also provides perspective into the intertwined, inescapable, and often uneasy relationship between these substances and human culture, economics, and politics-for example, how individuals become physically or psychologically addicted to alcohol, cocaine, nicotine, and opiates, while governments become financially "addicted" to the revenue, such as taxes, that can be collected from the sale and use of these substances. Presents a historical review of four plant-derived drugs-alcohol, cocaine, nicotine, and opiates-and their effects throughout human civilization, as well as a fascinating exploration of the mystery and misery of addiction Provides comprehensive explanations of medical and psychiatric effects of these drugs Supplies stories of people who made discoveries about these drugs or who had their lives altered by them Describes the discovery of the way in which the brain works Includes illustrations of brain pathways and of the four plants of origin for these drugs, and maps showing drug trade triangles

This compelling volume explores the various aspects of Native American healing found cross-culturally in North America, including Canadian and Inuit cultures. In Encyclopedia of Native American Healing, the extensive entries span topics such as renowned healers throughout history in the various cultures; societies and divisions into which healers were categorized; sacred objects employed in healing rituals and how each was used; the different types of healing ceremonies conducted; plants used to increase healing powers; symbolic motifs used in healing rituals; major concepts that form the healing traditions; and major scholars of Native American healing. This reference work will appeal to the interested layperson as well as students of Native American cultures.

Currently most published books on enteral nutrition support focus only on issues such as the rationale; specific nutrient requirements for various disease conditions; and practical approaches to the delivery, monitoring, and complications preventions while providing enteral nutrition support. None offer information relating to the developmental aspects of enteral foods, e.g. processing technology, types of ingredients, physicochemical and nutritional characteristics, shelf life evaluations, etc. These aspects are critical because they affect the overall acceptability, tolerance, and effectiveness of enteral nutrition support.

Medical Foods from Natural Sources discusses the development of the enteral foods from the natural sources for the patients, such as barley, rice, eggs, milk, etc., and presents methods on how to prepare enteral foods from natural sources for use. The book fills the gap in the literature by discussing the history of enteral nutrition; interpreting the statistics regarding worldwide need for enteral nutrition support and cost involved; enumerating the processing technology to develop natural ingredients-based enteral foods; and describing the results of prospective clinical trials and case studies conducted to evaluate the effectiveness of enteral foods based on natural ingredients.

When Downeast "local" Annette Fiorno is found at the bottom of a ravine, "outsider" and relapsed drug addict Jimmy Sedgwick is accused of murder. Unassuming Maine lawyer Rob Hanston and big shot attorney Shawn Marks form an unlikely legal team as they attempt to discredit the overwhelming evidence. Addiction on Trial, the first in a series of Shawn Marks Thrillers, revolves around the murder cases of Attorney Marks, an egotistical yet likable high-powered Boston attorney who can juggle an array of female companions without taking his eye off the legal challenges of his work. Addiction on Trial sends a powerful message of societal discrimination toward drug addicts and explores common misperceptions about what drug addiction really is - a chronic illness requiring a similar treatment approach as other chronic diseases. Medical and behavioral aspects of addiction are woven into the intrigue of this thriller, which culminates in a riveting murder trial.

The use of recreational drugs of abuse by large numbers of individuals in this country and abroad has aroused serious concerns about the consequences of this activity. For example, it is recognized that marijuana is currently widely used as a recreational drug in the United States as well as other countries. Similarly, abuse of cocaine, especially crack cocaine, is considered to be an epidemic. "The war on drugs" by the US Government was directly aimed at the illicit use of cocaine, marijuana, and opiates as well as other drugs of abuse. Furthermore, alcohol is also considered a major problem of abuse in this country as well as in many other countries. It is estimated there are at least 10 million alcoholics in the United States alone. A signi?cant portion of those hospitalized with infectious diseases are alcoholics. Similarly, there have been many reports of association between marijuana use and increased susceptibility to infection as well as a re- tion between use of opiates and infections. The relationship between drug abuse and increased incidence of various infections has stimulated increased investi- tion of whether and how such drugs affect immune function, especially imp- tant for resistance against infectious agents. During the last decades, a wide variety of studies have shown that drugs of abuse, including marijuana, cocaine, or opiates, as well as alcohol, alter both neurophysiological as well as pathological responses of individuals.

In this new volume in the series Research and Perspectives in Neurosciences the authors have presented and discussed their findings in the fields of speech and language disorders, X-linked mental retardation, gene therapy in the CNS, memory and learning disorders and other fields.

This book brings together critical perspectives on some of the recent claims associated with the obesity crisis. It develops both theoretical and conceptual arguments around the obesity debate, as well as taking a more practical focus in terms of implications for the health professions to outline an agenda for a 'critical weight studies'.