Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. "The Effects of Drug Abuse on the Human Nervous System "presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers.
*A comprehensive reference on the effects of drug addiction on the human nervous system
*Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs
*Includes foundational science chapters on the biology of addiction
*Details challenges in diagnosis and treatment options

This issue of Nursing Clinics of North America is Guest Edited by Al Rundio, RN, at Drexel University and will focus on Addictions. Article topics will include Office-Based Opioid Treatment, Addictions and Pregnancy, Peer Assistance, Relapse Prevention for Addictions, Adolescents and Addiction, Use of Photo Voice in Addictions, Health Promotion and Prevention Strategies, Maintaining Sobriety and Recovery, and SBIRT (Screening Brief Interventio and Treatment.)

Why is music so important to most of us? How does music help us both in our everyday lives, and in the more specialist context of music therapy? This book suggests a new way of approaching these topical questions, drawing from Ansdell's long experience as a music therapist, and from the latest thinking on music in everyday life. Vibrant and moving examples from music therapy situations are twinned with the stories of 'ordinary' people who describe how music helps them within their everyday lives. Together this complementary material leads Ansdell to present a new interdisciplinary framework showing how musical experiences can help all of us build and negotiate identities, make intimate non-verbal relationships, belong together in community, and find moments of transcendence and meaning. How Music Helps is not just a book about music therapy. It has the more ambitious aim to promote (from a music therapist's perspective) a better understanding of 'music and change' in our personal and social life. Ansdell's theoretical synthesis links the tradition of Nordoff-Robbins music therapy and its recent developments in Community Music Therapy to contemporary music sociology and music studies. This book will be relevant to practitioners, academics, and researchers looking for a broad-based theoretical perspective to guide further study and policy in music, well-being, and health.

The most important writings on the psychoanalytic understandings and treatments of drug and vice addiction Drug abuse, alcoholism, compulsive gambling, and other destructive addictions plague our society. Theories of addiction locate its cause variously-in factors related to the substance, the addict's personality, or to the addict's environment. Arguments about effective treatment programs are fierce. Essential Papers on Addiction presents the most important writing and the various sides of the debate on the psychoanalytic understanding and treatment of addiction. Daniel Yalisove outlines the history of the treatment of addiction and introduces important psychoanalytic concepts used in understanding addicts. The book includes case studies which illustrate the course of addiction and presents the work of the most influential theorists in the field. Divided into eight sections focusing on historical work on addiction, psychoanalytic theories of addiction, transference and countertransference issues in treating addiction, psychoanalytic treatment for the addictions, psychoanalytic therapy and disease concepts, and psychiatric illness and addiction, this definitive volume includes contributions by the most experienced and renowned experts on the subject. Contributors include S. Freud, E. Glover, S. Rado, R. P. Knight, L. Wurmser, N. E. Zinberg, H. Krystal, D. Jacobs, R. Fine, J. Gustafson, C. L. Brown, M. L. Selzer, V. Davidson, J. Imhof, R. Hirsch, R. E. Terenzi, M. E. Chafetz, A. Silber, R. J. Rosenthal, E. M. Pattison, M. B. Sobell, L. C. Sobell, J. E. Zweben, E. Simmel, B. Brickman, E. J. Khantzian, R. D. Weiss, S. M. Mirin, A. T. McLellan, and H. J. Richards.

"Keane's work is thoughtful and thought provoking and incorporates elements of medical history and philosophy."--"Psychiatric Services"

"A theoretically engaging exploration of the arbitrariness of the field of addiction studies."
--Robert Granfield, co-author of "Coming Clean"

We assume that there is something wrong with addiction. But how exactly is it bad to be an addict? What's Wrong with Addiction? explores the ways in which our views of addiction categorize certain ways of being as unnatural, diseased, and self-destructive, often working to reinforce existing social hierarchies. Under the rubric of addiction, pleasure and desire are demonized, while the addict is viewed as damaged and in need of physical and moral rectificaiton.

Keane examines the ambiguities in medical science's quest to construct addiction in chemical and biological terms, revealing the strains in the oppositions between disease and health, and addiction and normality. She demonstrates how these strains have become more insistent as the net of addiction has spread wider, moving beyond chemical substances to other problems of consumption and conduct such as compulsive eating and sex addiction. The book also critically examines the ideals of health, freedom, and happiness found in popular self-help literature, suggesting that it is the practices of self-surveillance and self-interrogation promoted in recovery guides which actually produce the inner self as an object of concern.

First published in 1943, "Vitamins and Hormones" is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, "Vitamins and Hormones" continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

This volume focuses on obesity.

Key features:

* Contributions from leading authorities * Informs and updates on all the latest developments in the field

Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans.
Subject matter: obesity is an epidemic and G protein-coupled receptors are promising drug targets, with significant potential as new anti-obesity drugs.

Chapters are written by leading experts.

First published in 1943, "Vitamins and Hormones" is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, "Vitamins and Hormones" continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

This volume focuses on anorexia.

Key features:

* Contributions from leading authorities * Informs and updates on all the latest developments in the field

This issue of Sleep Medicine Clinics, Guest Edited by Max Hirshkowitz, PhD, D ABSM, will focus on Fatigue, with article topics including: Fatigue, Sleepiness, and Safety; Assessment, and Methodology; Fatigue and Neurological Disorders; Cardiopulmonary Disorders and Fatigue; Cancer and Fatigue; Psychiatric Disorders and Fatigue; Organ Transplantation and Fatigue; Fatigue in Other Medical Disorders; Sleep Disorders and Fatigue; The Pharmacology of Fatigue and Sleepiness; and Fatigue Management Strategies.

Edited by Kenneth A. Jacobson and Michael F. Jarvis
The roles of extracellular purines and pyrimidines in cellular homeostasis and disease etiology have come to be understood gradually over the past 40 years. However, due to the recent cloning and expression of receptors for ATP and adenosine, novel compounds have been developed with unique therapeutic potential for the treatment of thrombosis, stroke, epilepsy, chronic pain, immunological disorders, and cancer. As a result, the study of adenosine- and ATP-mediated responses in cellular regulation is entering a phase of opportunity and development unmatched since the days of serotonin receptor research in the 1970s.
The only definitive book on the topic, Purinergic Approaches in Experimental Therapeutics covers all of the major therapeutic applications of purinergic receptors and reflects the very latest developments in this new area of therapeutic research. Twenty-eight chapters, authored by an international group of contributors who are the leading authorities in the field, provide details on molecular pharmacology; medicinal chemistry; and therapeutic implications, including cardiology, metabolism, immunology, neurology, and cancer.
Among the topics covered:
* Purinergic Neurotransmission and Neuromodulation: A Historical Perspective
* Adenosine Receptor Subtypes: New Insights from Cloning and Functional Studies
* Modulators of Adenosine Uptake, Release, and Inactivation
* Cardiac Electrophysiology of Adenosine: Antiarrhythmic and Proarrhythmic Actions
* Purinergic Modulation of Gastrointestinal Function
* The Role of Adenosine in Asthma
* ATP in Brain Function
* ATP in the Treatment of Cancer

For researchers in pharmacology, physiology, molecular biology, and medicinal chemistry, Purinergic Approaches in Experimental Therapeutics heralds an exciting new era in the understanding of purinergic neurotransmission and the development of novel therapeutic modalities.

This brand new book is the first of its kind dedicated to exercise and fitness training after stroke. It aims to provide health and exercise professionals, and other suitably qualified individuals, with the necessary information to design and evaluate exercise and fitness programmes for stroke survivors that are safe and effective. The content is based on current evidence and aligned with national clinical guidelines and service frameworks, highlighting the importance of physical activity in self-management after stroke. The book has also been written for stroke survivors and carers who may be interested in physical activity after stroke. Exercise and Fitness Training After Stroke comprehensively discusses the manifestations of stroke and how stroke is managed, the evidence for exercise and fitness training after stroke, how to design, deliver, adapt and evaluate exercise, as well as how to set up exercise services and specialist fitness training programmes for stroke survivors. Includes detailed background in stroke pathology, stroke management and how post-stroke problems may affect the ability to participate in exercise Dedicated to evidence-based exercise prescription with special considerations, cautions and therapy-based strategies for safe practice Covers issues of a professional nature, including national occupational standards, exercise referral pathways, as well as risk assessment and management related to stroke survivors Quality content from a highly qualifi ed, experienced and respected multidisciplinary team

Sleep disorders are a widely recognized consequence of many neurological pathologies. This issue of Neurologic Clinics features the following articles: Sleep Physiology; Sleep Assessment Tools for the Neurologist; Fitting Sleep into Neurological Practice;? Insomnia; Parasomnias and look-alikes; Sleep Apnea: Obstructive and central; Restless Legs syndrome; Circadian Rhythm; Pediatric Sleep Disorders; Dementia;? Stroke; Epilepsy; CNS Immunological and Infectious; Movement Disorders; Neuromuscular; Headache; Traumatic Brain Injury; and? Psychiatry in Sleep.

This issue of Sleep Medicine Clinics, Guest Edited by Richard Castriotta, MD of the University of Texas, will focus on Sleep and Neurorehabilitation. Article topics will include TBI and Sleep, Circadian Rhythm Disorders, Insomnia, and Stroke and Sleep.

This issue of Sleep Medicine Clinics, Guest Edited by Teofilo Lee-Chiong MD, will focus on Biology of Sleep, with article topics including: Neurology of Sleep; Normal Sleep and Circadian Rhythms: Neurobiologic Mechanisms Underlying Sleep and Wakefulness; Physiology of Sleep Disordered Breathing; Evaluation of the Patient Who Has Sleep Complaints: A Case-Based Method Using the Sleep Process Matrix; Sleep States, Memory Processing, and Dreams; Neurobiologic Mechanisms in Chronic Insomnia; Sleep Behavior and Sleep Regulation from Infancy through Adolescence: Normative Aspects; Biological Timekeeping; Neurologic Basis of Sleep Breathing Disorders; Genetics of Sleep Timing, Duration, and Homeostasis in Humans; Sleep in Normal Aging; Modulation of Endocrine Function by Sleep-Wake Homeostasis and Circadian Rhythmicity; Cardiac Activity and Sympathovagal Balance During Sleep; Sleep and Cytokines; Neuropharmacology of Sleep and Wakefulness; Staging Sleep; Respiratory Physiology During Sleep; and Cyclic Alternating Pattern (CAP), Sleep Disordered Breathing, and Automatic Analysis

Nutrition in the Prevention and Treatment of Disease has been proving itself in the classroom for nearly 10 years and is praised as being accessible, applicable and a valuable textbook. It focuses specifically on the relationship between disease and nutrition, an area of ever increasing interest and concern as health care costs and availability continue to be an issue worldwide. Now reaching beyond just the individual healthcare concern, the potential for nutritional interventions to improve health status is also of heightened interest to public health professionals who are faced with an aging, obese, at-risk-of-diabetes population who may or may not have access to insurance. This textbook is the foundation of understanding how nutrition can be used to improve health status.

New to this edition:

100% overall new material. 26 new authors or co-authors and all chapters have been completed updated

4 completely new chapters: "

Surgery for Severe Obesity

Snacking and Energy Balance in Humans

Phytochemicals in the Prevention and Treatment of Obesity and Its Related Cancers

Bioavailability and Metabolism of Bioactive Compounds from Foods "

New section on "Dietary Bioactive Compounds for Health" explores bioactive components present in edible plants of particular interest for the prevention of disease

New to the obesity section is a chapter on the management of patients who have undergone surgical treatment for obesity
Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences librariesIntegration of food issues with nutrition provides a unique perspective to disease prevention/controlMaterial in the book is up-to-date with current researchIndividual sections of the book can be used for mini-courses or in-depth studyDiversity of material makes this text useful for nutritional scientists and also for upper division nutrition course work

Portable Sleep monitoring is a very important method of diagnosis and follow-up for sleep-disordered breathing.? This state-of-the-art issue reviews the most recent information on classification, technical specifications and types of portable monitors, use and limitations of portable monitoring with integration into positive airway pressure treatment. use of portable monitors in children and in patients with oral appliances.? Use of portable monitoring for SDB treatment with upper airway surgery is also discussed.? Current published standards incliding CMS requirements for portable monitoring are reviewed.? Outcome measures, illustrative cases, and a comparison with polysomnogram are included.? Finally, future directions are discussed.

This issue of Nursing Clinics includes the following topics: Nursing interventions for smoking cessation; tobacco cessation clinics; Cessation strategies for pregnant and postpartum mothers; Evidence-based cessation strategies and policies for college-age smokers; Evidence-based cessation strategies for rural communities; Gender differences and tobacco cessation; Optimizing tobacco cessation outcomes; Community based participatory research and cessation interventions; Use of quit-lines for cessation; Advocacy and smoke-free laws; Hookah use in adolescents and adults; Chewing tobacco; and E-cigarettes.

First published in 1943, "Vitamins and Hormones" is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, "Vitamins and Hormones" continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

This volume focuses on sleep hormones.

Key features:

* Contributions from leading authorities * Informs and updates on all the latest developments in the field

This issue on Sleep Electroencephalography (EEG) gives an overview of Electrophysiological readings in sleep with such articles as "The Nuts and Bolts of EEG? and "How the Sleep/Wake EEG Changes Across the Lifespan.? Identifying abnormal EEG activity and patterns in the Electroencephalographic readings is also discussed.? The issue then further focuses in on Seizures and the EEG; specifically, how EEG can be used to diagnosis and identify seizure disorders and differentiate seizures from other paroxysmal nocturnal events, and to diagnose other primary sleep disorders in people with epilepsy.

Excessive Sleepiness, or hypersomnia, is one of the most common sleep complaints.? In this issue, Dr. Alon Avidan of UCLA brings together a set of articles that offer a completely updated overview of hypersomnia, from neurophysiology of sleepiness and wakefulness to quality of life issues and public health.? The main focus of the issue is the diagnosis and treatment of hypersomnia, including objective and subjective measurement of sleepness, biomarkers of sleepiness, narcolepsy, and hypersomnia in medical, neurological and psyhchiatric comorbidities. Excessive sleepiness among specific patient populations (children, elderly) and periodic hypersomnia are discussed.? Pharmacotherapy of hypersomnia is given special attention, as are behavioural treatments.

Sleep Loss and Obesity: Intersecting Epidemics represents a major contribution to the field of sleep medicine. It is a comprehensive review of the neurobiology of sleep, circadian timing and obesity, the deleterious effects of sleep loss and obesity on health, and the worrisome associated social and medical costs in a range of patient populations and overall to society. The number of individuals who are obese has reached alarming levels. As a result, the incidence of Type 2 diabetes, cardiovascular disorders, heart disease, and kidney failure have also increased. The surgeon general estimates that the total annual cost of obesity in the US is about $117 billion. This cost is expected to escalate significantly because the number of overweight and obese children is increasing rapidly. Indeed, the new generation is expected to have a shorter life-span then their parents. In addition, sleep loss is emerging as an important contributing factor to obesity. People who sleep less or are sleep deprived tend to eat more, especially carbohydrates, and have a higher body mass index. Increased weight restricts the upper airway, causing obstructive sleep apnea and further sleep loss. In the end there is a vicious cycle of weight gain and sleep loss. In the past few years there has been a tremendous growth in our understanding of brain mechanisms controlling energy metabolism. Interestingly the neurons regulating waking also regulate feeding. There is also a mechanism that regulates the timing of feeding and sleep. In shift-workers this system is likely to be disturbed, and this has an adverse impact on both feeding and sleep. Sleep Loss and Obesity: Intersecting Epidemics is the first title to clearly examine how obesity and sleep loss are interacting epidemics. This fascinating title makes the link between energy metabolism, sleep and circadian timing; identifies poor sleep as a risk-factor for obesity in children and adults and offers treatment strategies for obstructive sleep apnea and obesity. This book will be a vital source of information for all physicians interested in sleep disorders and obesity. It will also be of value to neuroscientists, health system administrators, and policy makers.

As technology becomes an increasingly vital aspect of modern social interaction, the field of disability informatics and web accessibility has made significant progress in consolidating theoretical approaches and exploring new application domains for those with motor and cognitive disabilities. Disability Informatics and Web Accessibility for Motor Limitations explores the principles, methods, and advanced technological solutions in the use of assistive technologies to enable users with motor limitations. This book is essential for academia, industry, and various professionals in fields such as web application designers, rehabilitation scientists, ergonomists, and teachers in inclusive and special education. This publication is integrated with its pair book Assistive Technologies and Computer Access for Motor Disabilities.