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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Toxicology (non-medical)

Ecotoxicology of Amphibians and Reptiles (Hardcover, 2nd edition): Donald W. Sparling, Greg Linder, Christine A. Bishop, Sherry... Ecotoxicology of Amphibians and Reptiles (Hardcover, 2nd edition)
Donald W. Sparling, Greg Linder, Christine A. Bishop, Sherry Krest
R6,705 Discovery Miles 67 050 Ships in 9 - 17 working days

Building on the success of its popular predecessor, the second edition of Ecotoxicology of Amphibians and Reptiles presents newly available findings on the species that are important environmental indicators. This new edition covers nearly twice as many topics as the first, including recent developments in the ecotoxicology of amphibians and reptiles, the current status of these animals, and intrinsic factors that affect their susceptibility to contaminants. The book also provides the latest information on specific groups of contaminants and their effects and body burdens in herpetafauna. After a review of how contaminants interact with other ecological factors, the text explores concerns for the future. New in the second edition: New research on the effects of pesticides, heavy metals, endocrine disrupting chemicals, and UVB Increased focus on the effects of contaminants rather than merely reporting residue information A synthesis of information on atrazine and its effects on gonads at low concentrations Coverage of the potentially alarming new cadre of chemicals that have recently or are about to come on the market for which there is very little or no information Important advances in surveying and monitoring One of the major factors behind the writing of the first edition was the worldwide phenomenon of declining amphibian populations. Although this decline has not abated, the breadth of research into its causes has expanded significantly. With chapter contributors carefully selected by the team of editors as leaders in their fields, this book provides an authoritative compendium of the most recent information on effects and residues coupled with a syntheses of what these numbers mean to science and policy.

Endocrine Toxicology (Hardcover, 3rd edition): J. Charles Eldridge, James T. Stevens Endocrine Toxicology (Hardcover, 3rd edition)
J. Charles Eldridge, James T. Stevens
R3,936 R3,738 Discovery Miles 37 380 Save R198 (5%) Ships in 12 - 19 working days

Examines endocrine toxicologya (TM)s increased importance in environmental safety issues due to legislative directives established over the past ten years.

With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system.

Covering all principal areas of EPA concern, Endocrine Toxicology, Third Edition provides:

  • putative endocrine disruptors and mechanisms of endocrine toxicity
  • the history and status of the regulatory process
  • mechanisms of toxic effects in various hormonal systems
  • comparisons of the endocrine responses in humans, livestock, and wildlife
  • testing methods in mammalian, fish, avian, and amphibian models
  • valuable insight into the approaches of various personnel in the field, including: government officials who make and oversee policy; scientists in charge of development and validation of testing methods; basic researchers who identify toxic mechanisms; and manufacturers responsible for environmentally benign product certification
Algal Toxins: Nature, Occurrence, Effect and Detection (Hardcover, 2008 ed.): Valtere Evangelista, Laura Barsanti, Anna Maria... Algal Toxins: Nature, Occurrence, Effect and Detection (Hardcover, 2008 ed.)
Valtere Evangelista, Laura Barsanti, Anna Maria Frassanito, Vincenzo Passarelli, Paolo Gualtieri
R5,812 Discovery Miles 58 120 Ships in 10 - 15 working days

This volume contains the lectures and seminars given at the NATO Advanced Study Institute on "Sensor Systems for Biological Threads: The Algal Toxins Case," held in Pisa, Italy in October, 2007. The Institute was sponsored and funded by the Scientific Affairs Division of NATO. It is my pleasant duty to thank this institution. This ASI offered updated information on how far the research on algal toxins has gone in the exploration of structures, biosynthesis and regulation of toxins, and the development of technology for bio-monitoring these c- pounds. Algae can form heavy growths in ponds, lakes, reservoirs and sl- moving rivers throughout the world; algae can house toxins which are - ually released into water when the cells rupture or die. Hundreds of toxins have been identified so far. Detection methods, including rapid screening, have been developed to help us learning more about them, especially to find out which toxins are a real threat for people and what conditions encourage their production and accumulation. Early detection of algal toxins is an - portant aspect for public safety and natural environment, and significant efforts are underway to develop effective and reliable tools that can be used for this purpose.

Ecotoxicology and Chemistry Applications in Environmental Management (Paperback): Sven Erik Jorgensen Ecotoxicology and Chemistry Applications in Environmental Management (Paperback)
Sven Erik Jorgensen
R1,857 Discovery Miles 18 570 Ships in 12 - 19 working days

Ecotoxicology and Chemistry Applications in Environmental Management describes how to set up an integrated, holistic approach to addressing ecotoxicological problems. It provides detailed explanations in answer to questions like "Why is it necessary to apply an integrated approach?" and "How does one apply an integrated environmental management approach?" Highlighted topics of the book include Environmental chemical calculations QSAR estimation methods Toxic substance interference with other environmental problems Using diagnostic ecological subdisciplines for solutions Cleaner production methods and technologies Environmental risk assessment Addressing one of the most difficult tasks today, this book provides a much-needed holistic view for translating scientific knowledge and research results into effective environmental management measures. Rooted in a seven-step method, it integrates examination and quantification of an environmental problem and describes the use of ecological diagnostic tools to develop a diagnosis for ecosystem health. It also presents methods for choosing and using solutions or combinations of solutions to tackle problems.

Particulate Plastics in Terrestrial and Aquatic Environments (Hardcover): Nanthi S. Bolan, M. B. Kirkham, Claudia Halsband,... Particulate Plastics in Terrestrial and Aquatic Environments (Hardcover)
Nanthi S. Bolan, M. B. Kirkham, Claudia Halsband, Dayanthi Nugegoda, Yong Sik Ok
R5,584 Discovery Miles 55 840 Ships in 12 - 19 working days

The manufacture of plastic as well as its indiscriminate disposal and destruction by incineration pollutes atmospheric, terrestrial, and aquatic ecosystems. Synthetic plastics do not break down; they accumulate in the environment as macro-, micro-, and nanoplastics. These particulate plastics are a major source of pollutants in soil and marine ecosystems. Particulate Plastics in Terrestrial and Aquatic Environments provides a fundamental understanding of the sources of these plastics and the threats they pose to the environment. The book demonstrates the ecotoxicity of particulate plastics using case studies and offers management practices to mitigate particulate plastic contamination in the environment. Features * Describes physical and chemical properties of particulate plastics in terrestrial and aquatic ecosystems * Presents information on characteristics of particulate plastics as impacted by weathering processes * Provides numerous approaches for managing particulate plastic contamination * Identifies sources of particulate plastics in the environment; distribution and characteristics of particulate plastics; and management strategies of particulate plastics Written by a global team of scientists, this book is for researchers in the fields of environmental safety and waste management or individuals interested in the impact of particulate plastics on environmental health.

High Performance Liquid Chromatography in Pesticide Residue Analysis (Paperback): Tomasz Tuzimski, Joseph Sherma High Performance Liquid Chromatography in Pesticide Residue Analysis (Paperback)
Tomasz Tuzimski, Joseph Sherma
R1,605 Discovery Miles 16 050 Ships in 12 - 19 working days

HPLC is the principal separation technique for identification of the pesticides in environmental samples and for quantitative analysis of analytes. At each stage of the HPLC procedure, the chromatographer should possess both the practical and theoretical skills required to perform HPLC experiments correctly and to obtain reliable, repeatable, and reproducible results. Developed to serve as a detailed practical guide, High Performance Liquid Chromatography in Pesticide Residue Analysis is a comprehensive source of information and training on state-of-the-art pesticide residue methods performed with the aid of HPLC. The book presents the pros and cons of HPLC as a flexible and versatile separation and analysis tool with multiple purposes and advantages in investigations of pesticides for food and plant drugs standardization, promotion of health, protection of new herbal medicines, and more.

Handbook of Pesticides - Methods of Pesticide Residues Analysis (Paperback): Leo M.L. Nollet, Hamir S. Rathore Handbook of Pesticides - Methods of Pesticide Residues Analysis (Paperback)
Leo M.L. Nollet, Hamir S. Rathore
R1,646 Discovery Miles 16 460 Ships in 12 - 19 working days

This handbook provides a systematic description of the principles, procedures, and technology of the modern analytical techniques used in the detection, extraction, clean up, and determination of pesticide residues present in the environment. This book provides the historical background of pesticides and emerging trends in pesticide regulation. The text discusses various techniques for analysis, including supercritical fluid extraction, disposable electrochemical biosensors, matrix solid-phase dispersion, volatmetric methods, and liquid chromatography. The authors also address the scope and limitation of NEEM products in plant protection as well as the analysis of medicinal plants.

Risk Assessment with Time to Event Models (Paperback): Mark Crane, Michael C. Newman, Peter F. Chapman, John S. Fenlon Risk Assessment with Time to Event Models (Paperback)
Mark Crane, Michael C. Newman, Peter F. Chapman, John S. Fenlon
R1,158 Discovery Miles 11 580 Ships in 12 - 19 working days

How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a pollutant for six months or more? Time to event methods are the key to answering these types of questions. Risk Assessment with Time to Event Models is the first comprehensive treatment of these methods in the context of ecological risk assessment. Leading experts from industry, academia, and government regulatory agencies explain how these methods can be used to extract more useful information from laboratory data than is present in simple summary statistics like 48-h LC50. The book offers a clear introduction to the field through several approaches, from the introductory to the more mathematical. Risk Assessment with Time to Event Models demonstrates the relevance of time in the analysis and reporting of toxicity data through the use of practical examples from the field of environmental toxicology. It also incorporates helpful analogies from other disciplines that commonly use time to event modeling.

Reviews of Environmental Contamination and Toxicology Volume 247 (Hardcover, 1st ed. 2019): Pim de Voogt Reviews of Environmental Contamination and Toxicology Volume 247 (Hardcover, 1st ed. 2019)
Pim de Voogt
R2,881 Discovery Miles 28 810 Ships in 10 - 15 working days

Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Environment and Chemicals in Agriculture (Hardcover, 1986 ed.): Winteringham Environment and Chemicals in Agriculture (Hardcover, 1986 ed.)
Winteringham
R8,538 Discovery Miles 85 380 Ships in 10 - 15 working days

This work contains the proceedings of the 1984 Environment and Chemicals in Agriculture symposium, held in Dublin, Ireland.

Why the Dose Matters - Assessing the Health Risk of Exposure to Toxicants (Hardcover): Urs A. Boelsterli Why the Dose Matters - Assessing the Health Risk of Exposure to Toxicants (Hardcover)
Urs A. Boelsterli
R4,783 Discovery Miles 47 830 Ships in 12 - 19 working days

• Familiarizes the reader with the basic terminology applied to toxicology • Explains how the exposure to a chemical is critically important when estimating the human health risk • Provides a balanced approach, neither spotlighting sensational findings nor downplaying potential real risks

Determination of Metals and Anions in Soils, Sediments and Sludges (Paperback): T. R Crompton Determination of Metals and Anions in Soils, Sediments and Sludges (Paperback)
T. R Crompton
R1,467 Discovery Miles 14 670 Ships in 12 - 19 working days

Determination of Metals and Anions in Soils, Sediments and Sludges is the first volume which comprehensively discusses the range of methods currently available for the analysis of metals and anions in soils, river and marine sediments and industrial sludges. There are specialist chapters on sampling, pollutant accumulation in sediments and bioaccumulation from soils to crops. A particular feature of this volume is its coverage of solid sewage, which is increasingly being applied to land as a fertilizer. An essential reference for chemists and toxicologists involved in water resource management, agrochemistry, fisheries and public health.

Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals (Paperback): Keith R. Solomon, Theo C.M.... Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals (Paperback)
Keith R. Solomon, Theo C.M. Brock, Dick De Zwart, Scott D. Dyer, Leo Posthuma, …
R2,120 Discovery Miles 21 200 Ships in 12 - 19 working days

A wide-ranging compilation of techniques, Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals describes methods of extrapolation in the framework of ecological risk assessment. The book, informally known as EXPECT, identifies data needs and situations where these extrapolations can be most usefully applied, making it a practical guide to the application of extrapolation procedures. It focuses on the extrapolation of chemical effects and covers the extrapolation of exposures in the context of interactions between toxicants and the matrix.

Endocrine Disrupters in Wastewater and Sludge Treatment Processes (Paperback): Jason W. Birkett, John N. Lester Endocrine Disrupters in Wastewater and Sludge Treatment Processes (Paperback)
Jason W. Birkett, John N. Lester
R2,016 Discovery Miles 20 160 Ships in 12 - 19 working days

Endocrine Disrupting Chemicals (EDCs) have been shown to produce changes in the endocrine system of organisms, leading to increases in cancers and abnormalities in reproductive structure and function. This book presents research on the endocrine-disrupting effects of sewage and industrial effluents, covering the sources, fate, and transport of EDCs, and sludge treatment and disposal options considered in regard to their implications for receiving environments. It also addresses the potential sources and analysis of these substances in waters, sediments, and sludges. In addition, the authors review current legislation and potential management strategies for endocrine disrupters in the environment.

Particle Toxicology (Paperback): Ken Donaldson, Paul Borm Particle Toxicology (Paperback)
Ken Donaldson, Paul Borm
R2,068 Discovery Miles 20 680 Ships in 12 - 19 working days

Exposure to particles in industry and mining and from accidental anthropogenic sources constitutes an ongoing threat. Most recently nanoparticles arising from advances in technology are exposing a wider population to pathogenic stimuli. The effects of inhaled particles are no longer confined to the lung as nanoparticles have the potential to translocate to the bloodstream, the brain, and other target sites. The new questions posed by nanoparticles underscore the importance of interdisciplinary research and exchange and highlight the need for new collaborations among disciplines in medicine, toxicology, chemistry, and material sciences. Particle Toxicology brings together the state of the science in particle physico-chemistry, cell biology, and toxicology in a single volume. While organized around the classical toxicology paradigm of exposure - dose - response, the book is unique in its emphasis on mechanistic toxicology. Preparing the reader with a brief historical overview and a conceptual framework for particle research, the book provides reviews on the mechanisms and properties of pathogenic particles and their effects on target cells at various sites in the body. The text describes how adverse effects are a consequence of deposition, translocation, and the complex issue of "dose" dominates. Contributions from leading researchers address particle-associated pro-inflammatory effects and inflammatory signaling, cellular and extracellular oxidative and nitrosative stress, particulate interactions in the pulmonary, cardiovascular, and central nervous systems, as well as genotoxic effects. Exemplar particles include quartz, asbestos, particulate material and nanoparticles. The book also covers mathematical modeling and human studies as avenues for future research. Responding to the evolving trend of consumer applications for particulate matter, Particle Toxicology provides the comprehensive resource for current knowledge from which to develop ne

Organic Pollutants - An Ecotoxicological Perspective, Second Edition (Paperback, 2nd edition): C.H. Walker Organic Pollutants - An Ecotoxicological Perspective, Second Edition (Paperback, 2nd edition)
C.H. Walker
R2,124 Discovery Miles 21 240 Ships in 12 - 19 working days

Difficult to measure accurately and deal with effectively, organic pollutants continue to be a major hazard in the environment. Significantly expanded, the second edition of Organic Pollutants: An Ecotoxicological Perspective describes the mechanistic basis of ecotoxicology, using major groups of pollutants as illustrative examples, and explores the problem of complex mixtures of chemicals. New in the Second Edition: Expanded coverage of complex pollution problems and the exploitation of recent scientific and technological developments to investigate them New chapters: Endocrine Disrupting Chemicals and their Environmental Impacts and Neurotoxicity and Behavioral Effects Additional information on biomarker approaches and new technologies, such as microarrays assays, developed to address complex pollution problems Tried-and-True Format Presents Updated Information Keeping the same format that made the first edition so popular, the text begins with coverage of the basic principles underpinning the environmental behavior and effects of organic pollutants. It then describes the properties and ecotoxicology of major pollutants, discusses some issues that arise after consideration of the material in the second part of the text, and explores future prospects. Mechanistic Approach Provides Basis for Development of New Strategies The book takes a bottom up approach, describing the mechanisms by which pollutants have harmful effects on living organisms and how these effects are translated into adverse changes at the population level. This mechanistic approach supplies the basis for development of new mechanistic biomarker assays, which in turn provide measures of toxic effect and not merely of exposure, and subsequently provide evidence of causality between pollutant levels and ecological changes.

Microbial Food Contamination (Paperback, 2nd edition): Charles L. Wilson, Ph.D. Microbial Food Contamination (Paperback, 2nd edition)
Charles L. Wilson, Ph.D.
R2,092 Discovery Miles 20 920 Ships in 12 - 19 working days

Divided into five parts, Microbial Food Contamination, Second Edition looks at emerging foodborne human pathogens andcomprehensively evaluates the microbiology, biochemistry, detection, risk, and threat of foodborne illness in today's global market. The first section introduces new insights into the pathogenic effect of E. coli, viral diseases, and protozoan parasites, as well as prions and other zoonotic diseases. It discusses mycotoxins and aflatoxins, particularly the carcinogenicity of aflatoxin B1 and the chemoprevention of liver cancer. Detection, Monitoring, and Control Presenting recent advances in the detection and monitoring of foodborne pathogens, section two reviews rapid electrochemical biosensors, new methods to detect prion diseases, and the use of polymerized chain reaction (PCR) for detection, identification, and typing of microorganisms. Section three examines control and prevention measures including Kosher and Halal food laws, and the use of naturally occurring antimicrobials, irradiation, and other physical control strategies. It also considers the genetic and biochemical control of aflatoxigenic fungi. International Regulation and Trade Globalization reduces traditional geographic borders that once prohibited pathogens from spreading and increases the risk of transnational outbreaks. The impact of this trend on international trade is evaluated in section four with a look at the implications of mad cow disease on the beef trade. It also provides an overview of programs to mitigate contamination such as the Codex Alimentarius and the International Food Safety Authorities Network. Bioterrorism Addressing the most frightening aspect of microbial contamination, section five explores bioterrorism and the different chemical, radiological, and biological agents that could be employed to deliberately contaminate food. Contributors take a critical look at present food protection strategie

Freshwater Bivalve Ecotoxicology (Paperback): Jerry L. Farris, John H. van Hassel Freshwater Bivalve Ecotoxicology (Paperback)
Jerry L. Farris, John H. van Hassel
R2,122 Discovery Miles 21 220 Ships in 12 - 19 working days

Responding to the growing need for an aggressive yet conservative approach to evaluating mussel populations, Freshwater Bivalve Ecotoxicology provides a collective review of the techniques and approaches for assessing contaminant impact on freshwater ecosystems. The editors incorporate coverage of research topics and management issues from a cross-section of scientists in the field. They explore current advances in general monitoring of population responses to stressors, fundamental concepts of ecotoxicology specific to burrowing bivalves, and useful insights that offer direction and priority for resolving specific problems challenging protection and conservation efforts. This book lays the groundwork with discussions of topics such as impact assessment, toxicokinetics, biomarkers, and pollution tolerance. The authors then explore fundamental concepts surrounding responses measured in freshwater bivalves as a consequence of chemical exposures or accumulated contaminants in target organs or tissues. They highlight the difficulties encountered with the laboratory culture of these organisms for toxicity testing or other controlled experiments, and examine the use of surrogate test organisms to relate sensitivities of response and reduce pressure on already impacted fauna. The book also reviews innovative field research using in situ bivalve toxicity testing, discusses effects-oriented tissue contaminant assessment, and concludes with threefour specific laboratory or combined field/laboratory ecotoxicology studies. A summary of methods from more than 75 laboratory toxicity studies conducted with freshwater mussels, the book provides an overview of a standardized method for conducting water-only acute and chronic laboratory toxicity tests with glochidia juvenile freshwater mussels. It focuses on studies that report measured contaminant treatments, had robust experimental designs, including replication of control and contaminant treatments, and were publish

Toxicology of Marine Mammals (Paperback): Joseph G. Vos, Gregory Bossart, Michel Fournier, Thomas O'Shea Toxicology of Marine Mammals (Paperback)
Joseph G. Vos, Gregory Bossart, Michel Fournier, Thomas O'Shea
R2,096 Discovery Miles 20 960 Ships in 12 - 19 working days

The activities of modern society have unleashed a range of toxic chemicals into the global environment. Many of these toxicants are now being detected in increasing quantities in the tissues of marine mammals, most notably in top predators who acquire relatively large amounts of toxic chemicals by ingesting contaminated prey. Toxicology of Marine Mammals focuses on the effects of natural and introduced toxicants on organs and systems in marine mammals. It provides overviews on health status and contamination, with subsequent chapters devoted to whales, pinnipeds, dolphins, polar bears, manatees, and sea otters. Internationally renowned researchers assess the mounting evidence for adverse effects on reproduction and the chemically-induced increased susceptibility to death from infectious diseases. The concluding chapter addresses perspectives and issues for the future. This compelling book features research from a vast geographic landscape ranging from the tropics to the Arctic, with case studies on intriguing areas of contamination such as the St. Lawrence River and the Baltic Sea. It identifies the severe threats that environmental contaminants pose to the health and future of marine mammals. It also makes an urgent call for legislation to regulate the incessant pollution ravaging our seas and devastating the marine mammal population worldwide. Toxicologists working in marine biology and veterinary medicine, conservation scientists, fisheries scientists, environmental scientists, and wildlife managers will all benefit from this comprehensive resource.

Thermodynamics and Ecological Modelling (Paperback): Sven E. Jorgensen Thermodynamics and Ecological Modelling (Paperback)
Sven E. Jorgensen
R2,118 Discovery Miles 21 180 Ships in 12 - 19 working days

Thermodynamics is used increasingly in ecology to understand the system properties of ecosystems because it is a basic science that describes energy transformation from a holistic view. In the last decade, many contributions to ecosystem theory based on thermodynamics have been published, therefore an important step toward integrating these theories and encouraging a more wide spread use of them is to present them in one volume. An ecosystem consists of interdependent living organisms that are also interdependent with their environment, all of which are involved in a constant transfer of energy and mass within a general state of equilibrium or dis-equilibrium. Thermodynamics can quantify exactly how "organized" or "disorganized" a system is - an extremely useful to know when trying to understand how a dynamic ecosystem is behaving. A part of the Environmental and Ecological (Math) Modeling series, Thermodynamics and Ecology is a book-length study - the first of its kind - of the current thinking on how an ecosystem can be explained and predicted in terms of its thermodynamical behavior. After the introductory chapters on the fundamentals of thermodynamics, the book explains how thermodynamic theory can be specifically applied to the "measurement" of an ecosystem, including the assessment of its state of entropy and enthalpy. Additionally, it will show economists how to put these theories to use when trying to quantify the movement of goods and services through another type of complex living system - a human society.

Activated Charcoal in Medical Applications (Paperback, 2nd edition): David Cooney Activated Charcoal in Medical Applications (Paperback, 2nd edition)
David Cooney
R2,089 Discovery Miles 20 890 Ships in 12 - 19 working days

Highlighting activated charcoal's great effectiveness in treating drug overdoses and poisonings in both humans and animals, this comprehensive, single-source reference brings together vital information from every significant study on the use of activated charcoal for medical purposes-describing all available charcoal products and their characteristics. Details activated charcoal's ability to reduce the systemic absorption of a vast array of drugs, chemicals, and biochemical substances-including analgesics, antipyretics, sedatives, alkaloids, snake venoms, and bacterial and fungal toxins.

Human Developmental Toxicants - Aspects of Toxicology and Chemistry (Paperback): James L. Schardein, Orest T Macina Human Developmental Toxicants - Aspects of Toxicology and Chemistry (Paperback)
James L. Schardein, Orest T Macina
R2,067 Discovery Miles 20 670 Ships in 12 - 19 working days

Presenting the first database of its kind, this unique reference illustrates the relationships between the chemistry and developmental toxicity of a number of important pharmaceuticals and industrial toxicants. Human Developmental Toxicants contains up-to-date and concise information on the chemical structures, properties, and biological activities for 50 known agents that adversely affect prenatal and postnatal human development in terms of growth, viability, structure, and function. This book presents data linking chemical and structural properties of specific toxicants as they relate to toxic effects, dosage, timing, and route of exposure. Focusing on one compound per chapter, the book also includes associated biological data from animals for each agent covered. Accompanying downloadable resources summarize all of the data discussed in the text within an electronic database. In addition, the CD contains three-dimensional structure representations and 49 calculated physicochemical and topological parameters of the selected molecules. This information is useful for building structure activity relationship (SAR) models linking the chemical properties with observed human developmental toxicity. As scientists continue to explore how chemicals alter human development, Human Developmental Toxicants contains the necessary information to further identify which chemical properties are responsible for adverse effects. This reference provides toxicologists, teratologists, chemists and other scientists with the latest data and information needed to perform risk assessments, predict chemicals that may produce developmental toxicity, and regulate harmful exposure.

Tolerance to Environmental Contaminants (Paperback): Claude Amiard-Triquet, Philip S. Rainbow, Michele Romeo Tolerance to Environmental Contaminants (Paperback)
Claude Amiard-Triquet, Philip S. Rainbow, Michele Romeo
R2,129 Discovery Miles 21 290 Ships in 12 - 19 working days

Tolerance, the ability of populations to cope with the chemical stress resulting from toxic contaminants, has been described in many organisms from bacteria to fungi, from phytoplankton to terrestrial flowering plants, and from invertebrates such as worms to vertebrates like fish and amphibians. The building of tolerance, be it by physiological acclimation or genetic adaptation, can have great consequences for the local biodiversity, and hence the ecology and ecosystem functioning of many of the world's habitats. Understanding the frequency of the occurrence of tolerance has tremendous implications for the sustainability of biodiversity and ecosystem functioning. Tolerance to Environmental Contaminants takes a multidisciplinary approach across contaminant types, habitats, organisms, biological levels of organization and scientific disciplines. The book examines the general principles governing the acquisition and biological consequences of tolerance, genetically or physiologically based, at different levels of biological organization, taxonomically from bacteria and archaea to flowering plants and vertebrates, and within organisms from molecular biology and biochemistry through physiology to whole organism, community, and ecosystem levels of organization. Presenting a state-of-the-art synthesis of the many aspects of the phenomenon of tolerance to environmental contaminants, this volume covers mechanisms of defense involved in the acquisition of tolerance, different classes of environmental contaminants, positive and negative ecological consequences of tolerance and the impact of tolerance in bacteria, plants, and insects on society. The reviews presented in this book supply the tools for carrying out more informed and therefore more reliable risk-benefit analyses when assessing the ecotoxicological risks to life in any of the contaminated habitats that now surround us in our industrialized society.

Jet Fuel Toxicology (Paperback): Mark L Witten, Errol Zeiger, Glenn David Ritchie Jet Fuel Toxicology (Paperback)
Mark L Witten, Errol Zeiger, Glenn David Ritchie
R2,051 Discovery Miles 20 510 Ships in 12 - 19 working days

Currently serving as a resource for the National Center for Toxological Research in their work with the Gulf Coast oil spill, this book presents current research conducted primarily by the airforce on the toxic effects of JP-8 jet fuel on the pulmonary, immune, dermal, and nervous systems. In all, the book considers 13 toxicology studies of significance, the results of which are currently shaping US armed services policy. It will enable all of the hydrocarbon industry to make better choices regarding fuel handling. Due to its widespread use, jet fuel is thought to be the largest toxicant exposure risk for U.S. Armed Services personnel. Taking a proactive approach to the potential dangers of repeated human exposure to hydrocarbon fuels, the Air Force Office of Scientific Research (AFOSR) sponsored a number of research projects during the last 20 years investigating health effects resulting from specific exposure to JP-8 (Jet Propellant-8). Jet Fuel Toxicology summarizes the newest and most important results of these extensive research programs carried out by hydrocarbon fuel research groups throughout the U.S. Each book chapter highlights one specific research area from the many topical areas comprising jet fuel toxicology. After examining the contents and general action of JP-8, the book looks at how the fuel affects various body functions highlighted by: Effects on daily inhalation on the respiratory system Acute and long-term neurotoxicological and neurobehavioral effects Both local and systemic toxicity following exposure through the skin Immunotoxicity from pulmonary and dermal exposures Genetic damage, as evidenced in studies of the blood and bone marrow of mice In all, the book considers 13 major toxicology areas of study, the results of which will enable all of the hydrocarbon industry to make

Aquatic Macrophyte Risk Assessment for Pesticides (Paperback): Lorraine Maltby, Dave Arnold, Gertie Arts, Jo Davies, Fred... Aquatic Macrophyte Risk Assessment for Pesticides (Paperback)
Lorraine Maltby, Dave Arnold, Gertie Arts, Jo Davies, Fred Heimbach, …
R2,085 Discovery Miles 20 850 Ships in 12 - 19 working days

Given the essential role that primary producers play in aquatic ecosystems, it is imperative that the potential risk of pesticides to the structure and functioning of aquatic plants is adequately assessed. An integration of regulatory and research information from key specialists in the area of environmental regulation, Aquatic Macrophyte Risk Assessment for Pesticides provides a state-of-the-art guide to ecotoxicological risk assessment. Written by well-known experts in the field of aquatic risk assessment, this book is a practical reference for the assessment of the risk of pesticides with herbicidal activity to aquatic macrophytes. The book supplies a concise, coherent, and science-based view from influential regulators, academics, and industry scientists. They address the selection of additional species, critical regulatory endpoints, and assessing the risk of plant protection products to aquatic macrophytes. They also present a clear description of key issues in macrophyte risk assessment, information on macrophyte test methods, suitable measurement endpoints, and data evaluation and interpretation. Filled with recommendations distilled from existing regulatory experiences of aquatic macrophyte risk assessment, the book includes case studies to identify issues, data gaps, and inadequacies in study design. It also identifies improvements to risk assessment that could be implemented immediately and those for which further research is needed. An authoritative resource, the book points the way to an improved approach to aquatic macrophyte risk assessment.

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