This book is a comprehensive review of the instrumental analytical methods and their use in environmental monitoring site assessment and remediation follow-up operations. The increased concern about environmental issues such as water pollution, air pollution, accumulation of pollutants in food, global climate change, and effective remediation processes necessitate the precise determination of various types of chemicals in environmental samples. In general, all stages of environmental work start with the evaluation of organic and inorganic environmental samples. This important book furnishes the fundamentals of instrumental chemical analysis methods to various environmental applications and also covers recent developments in instrumental chemical methods. Covering a wide variety of topics in the field, the book: * Presents an introduction to environmental chemistry * Presents the fundamentals of instrumental chemical analysis methods that are used mostly in the environmental work. * Examines instrumental methods of analysis including UV/Vis, FTIR, atomic absorption, induced coupled plasma emission, electrochemical methods like potentiometry, voltametry, coulometry, and chromatographic methods such as GC and HPLC * Presents newly introduced chromatographic methodologies such as ion electrophoresis, and combinations of chromatography with pyrolysis methods are given * Discusses selected methods for the determinations of various pollutants in water, air, and land Readers will gain a general review of modern instrumental method of chemical analysis that is useful in environmental work and will learn how to select methods for analyzing certain samples. Analytical instrumentation and its underlying principles are presented, along with the types of sample for which each instrument is best suited. Some noninstrumental techniques, such as colorimetric detection tubes for gases and immnosassays, are also discussed.

This title includes a number of Open Access chapters. The rate of identification of children with neurobiological disabilities has been on the increase in recent years. Millions of dollars in research are being spent to understand the factors influencing these increases. The articles within this compendium shed vital light on this issue, confirming that various "ordinary" chemical hazards-of the sort encountered by countless children in their everyday lives-are having serious impacts on development. This volume investigates the impact of exposure to tobacco smoke, household chemicals, lead, agricultural toxins, and flame retardants.

This title includes a number of Open Access chapters. This collection of timely chapters presents a nuanced study of environmental toxins and the risks they pose to children's development. The book details the impact of a number of commonplace environmental toxins, focusing on everyday exposure to tobacco smoke, lead, pesticides, and flame retardants. There is growing recognition that the impact of the environment on children's health is of critical importance for both current and future generations. In the last half-century, thousands of chemicals have been introduced into the environment with limited-although growing-research on the consequences of exposure. It has been proven that children and adolescents are far more vulnerable than adults to these environmental toxins by virtue of children's behaviors, higher metabolic rate, greater skin area relative to their volume, and still developing organ systems. Increased number of ear infections, poor asthma control, and learning disabilities are just some of the adverse outcomes that have been noted. This well-researched book: * Presents detailed information on why children are more vulnerable to everyday toxins * Discusses why new approaches to medical care are necessary that take into account children's unique physiology and development * Offers well-defined research on tobacco smoking on prenatal development as well as children's exposure to tobacco smoke during their early years, particularly the evidence of asthma and asthma-like symptoms * Examines the possible health effects of children born to mothers living in areas of natural gas development * Looks at the health effects of childhood exposure to environmental lead, using GIS technology to study areas of potentially high lead concentrations * Discusses the possible effects of agricultural pesticides on children's health during gestation * Presents studies on prenatal and adolescent exposure to PBDEs used as flame retardants in many household and commercial products to prevent fire This valuable book, edited by a pediatric clinician at Boston's Children's Hospital, provides a wealth of information on this important issue. The book concludes with an article by the World Health Organization, which offers a practical and comprehensive summary of a series of action steps. The book aims to create greater awareness to spur additional research, provide vital information to clinicians, and send a powerful message to government officials, putting pressure on them to develop policies that improve the quality of the environment and spare children the detrimental effects of such exposures.

This important new volume presents a plethora of research on the distribution of heavy metals in soils and rocks of natural habitats, farmlands, and urbanized areas along with the factors influencing their bioavailability. The authors evaluate the content of organic matter, soil acidity, mineral fertilizers, and more. Developed for ecologists and specialists in the field of environmental protection and the conservation of biological diversity, the book presents the problems of reducing the anthropogenic load on the surrounding countryside and focuses on sustainable agricultural development.

A UN report presented to the UN Human Rights Council in 2017 recognized that, "although pesticide use has been correlated with a rise in food production, it has had catastrophic impacts" on human health and the environment. The report acknowledged that "increased food production has not succeeded in eliminating hunger worldwide because of the many interacting factors involved. Reliance on hazardous pesticides is a short-term solution that undermines the rights to adequate food and health for present and future generations." It is hoped that the knowledge available in Synthetic Pesticide Use in Africa: Impact on People, Animals, and the Environment will both enlighten the reader to present serious concerns on the use of synthetic pesticides, and motivate society to make the changes necessary for the sustainable production of safe, nutritious, and affordable food for the anticipated 250 billion inhabitants of this Earth in 2050. Key Features: * Explains the relationship of synthetic pesticides to escalating noncommunicable human and animal diseases in Africa and developing countries. * Discusses the impact of the herbicide glyphosate on the health of humans, animals, and the environment. * Reviews the disease causing mode of action of glyphosate and other synthetic pesticides on nutrient density and human and animal bodies. * Warns of the special vulnerability of children to synthetic pesticide toxicity. * Recommends needed legal initiatives to use synthetic pesticides more judiciously. The book is divided into seven (7) sections: I. General Impact, explains the general impact of synthetic pesticides on the African people, their animals, and environment. II. Human Health, covers the impact of synthetic pesticides on the human body, while III, Children's Health, focuses on the special vulnerability of children to synthetic pesticides. IV. Animal Health describes the synthetic pesticide threats to animal production and sustainability. V. Environmental Health presents the threat of synthetic pesticides to soil microbiota and sustainable remediations. VI. Control Strategies discusses biologically-based alternatives to synthetic pesticides. Finally, VII. Reglatory Control presents some legal initiatives to combat the misuse of synthetic pesticides.

During the recent decades, social, political and academic endeavours have been made to improve environmental quality and reduce pollution. In particular, the ocean, sea and coastal areas show varying degrees of impact from the multiple human activities carried out in the terrestrial as well as in the aquatic environment. Ecology is a science which studies the relationship between organisms and the surrounding environment and in the modern era, the marine world is getting increasing attention. For centuries it has been the final reservoir of human garbage; later it became an oil farm with a concomitant increase of coastal population growth and unplanned growth of the fishing industry and the increasing use of sea routes for cargo transport and recreational uses (cruises). All this led to rising contamination with negative effects on biota and even human health. It is then imperative to know the current situation of the world's oceans: that is the main purpose of this book, to document at a glance the latest research in the field of ocean pollution.

This is the first comprehensive book on the biology and ecology of pufferfish, also known as blowfish, swellfish, and globefish. Covering 197 species of pufferfish recorded so far from the marine, brackish, and freshwater ecosystems of the world, this important volume expounds on the toxins and associated poisonings of pufferfish. Importantly, the volume also explores the many uses of pufferfish, such as in aquariums, for their nutritional and culinary value, and for their emerging uses in the treatment of pain. Topics covered include: biology and ecology of pufferfish profiles of the world's marine, brackish, and freshwater pufferfish species characteristics of TTX (tetrodotoxin) and STX (saxitoxin) of pufferfish pufferfish poisoning and symptoms: treatment and management aquarium uses of pufferfish nutritional and pharmaceutical values of pufferfish diseases and parasites of pufferfish and their management

This book presents a comprehensive review of the most recent studies on the impact of contaminants on the marine environment. Conventional and new information, as well as the latest techniques, are presented, which can be applied to several types of marine organisms from bacteria and fungi to animals and algae. Specific topics discussed include the impact of different contaminants on different organisms as well as different approaches and their outcomes in terms of impact assessment. The integration of these techniques is also discussed in order to attain sentinel species and biomarkers to be applied for assessing ecological quality and impact assessment programs and studies.

Modern technology using state-of-the-art equipment can now identify almost any toxin relevant to a legal issue. Techniques include gas chromatography, mass spectrometry, high-pressure liquid chromatography, and the combination of these methods. Forensic Toxicology: Medico-legal Case Studies demonstrates how the science of forensic toxicology acts as a bridge between medicine and law. Tracking the progression of toxicology findings from the laboratory to the courtroom, it prepares practicing toxicologists to write reports and testify at depositions and in court. The book explains the organization of clinical laboratories and includes sections on accreditation, quality control, method validation, and other critical topics. It provides an overview of the U.S. legal system, describes the process of writing a toxicology report, and offers techniques for deposition and courtroom testimony. Covering a broad range of topics, the book offers detailed analysis of situations ranging from the rare and unusual to those that toxicologists most often confront, including: Determining serum/blood ethanol levels Ethylene glycol poisoning Plant and animal toxins Alcohol intoxication and breathalyzer tests Synergistic effects of alcohol and drugs Prescription drug overdose Toxic torts Workers' compensation issues Written in an accessible and well-organized style, this volume is an essential guide for forensic toxicologists at all levels who need to understand how to best present the science of toxicology in the forensic arena.

Marine environment can be affected by several pollutants such as the presence of elements and their chemical species, pharmaceuticals, nanoparticles and other emerging contaminants. Environmental monitoring can be assessed by genomics, proteomics (i.e. redox proteomics), chemical speciation analysis and metallomics, metabolomics as well as other advanced strategies. The present book is a useful methodological tool for researchers and specialists in the field of analytical chemistry, environmental sciences, biochemistry, genomics and toxicology. The book includes for the first time the methodological aspects and applications related to chemical speciation and -omics strategies applied to marine environment.

Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) provides the most recent summary of toxicity data relevant to mammals, birds, reptiles, and amphibians, and provides values for use in risk assessment applications. Predicting the bioaccumulation of PFAS in terrestrial wildlife (including humans) has proven to be extremely complex. As a group, PFAS act differently than traditional non-ionic organic molecules, where PFAS can break down and reform, whereas some are demonstrated to be extremely persistent. Where sufficient data are provided, this book establishes toxicity reference values (TRVs), which are derived to assist in characterizing environmental sources of contamination and making risk-based decisions. Features: Provides toxicity reference values (TRVs) for vertebrates (mammals, birds, amphibians) for PFAS, where sufficient data are available, and includes objective supporting background information. Assigns a level of confidence to each TRV to provide the risk assessor with an understanding of the relative uncertainty associated with each value. Presents toxicity data in the formats of scatter diagrams and tables for quick review and assessment. Provides TRVs relevant for screening and decision making This book serves as a useful aid for risk assessors and managers in those industries that have sites contaminated with PFAS, consultants tasked with evaluating risks at such sites, and staff at regulatory agencies at various governmental levels, who need to know how much contamination is considered safe for wildlife. It will also appeal to researchers with an interest in filling the gaps in the current toxicological data for PFAS exposure.

Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

The coastal tropics comprise some of the most sensitive and yet the most understudied ecosystems in the world. Coastal plains and river valleys are also home to agriculture on a vast scale, and it is not surprising to find that streams and rivers receive the majority of agricultural runoff, carrying the residues of insecticides, fungicides and other pesticides into estuaries and coastal zones. There is a growing awareness of the urgent need to develop strategies to help productive, healthy and economically viable agriculture to coexist with natural resources. Pesticide Residues in Tropical Coastal Ecosystems brings together toxicology experts from around the world to assess pesticide burdens in many of the major food-producing tropical countries. It provides a unique set of case studies, chronicling pesticide usage and its ecotoxicological impact in coastal regions. A practical guide to recent research findings and applications, it is essential reading for environmental professionals, ecotoxicologists, marine chemists and agrochemists.

First Published in 1977, this set offers a comprehensive guide into the Toxic Substances Control Act of 1976. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for environmental health professionals, toxicologists, and other practitioners in their respective fields.

First Published in 1977, this set offers a comprehensive guide into the Toxic Substances Control Act of 1976. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for environmental health professionals, toxicologists, and other practitioners in their respective fields.

This book is a valuable contribution to the debate about the harmful effects of environmental toxicants on human health, which is a growing concern in the 21st century. Complementary chapters decipher the phenomena and highlight the latest developments in environmental toxicology, providing readers with a comprehensive overview of environmental toxicology and human health. Since the toxicants in question are not only chemical or biological in nature, but also include man-made electromagnetic fields, the book explores in detail multidisciplinary approaches to environmental toxicology, with a focus on the following five aspects: 1. The effects of man-made electromagnetic fields (RF-EMF) on human health proposed mechanisms and biological effects and measures). 2. An overview of nanotoxicity, nanomedicine and cancer research. 3. A bio-computational approach to the molecular interaction of environmental carcinogens with DNA. 4. The toxicology of environmental pollutants in the air, dust, soil, water and natural toxins in the environment: exposure and health. 5. Social insects as environmental indicators of ecotoxicological effects in different ecosystems. The book analyzes the carcinogenic, mutagenic, genotoxic and neurotoxic effects of both anthropogenic and natural toxins present in water, soil, air and our surroundings in the form of electro-pollution or electro-smog.

Reviews of Environmental Contamination and Toxicology provides concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Heavy metals and metalloids, singly or in combination, induce toxic manifestations either through acute or chronic pathology. In particular, long-term chronic exposure to diverse heavy metals and metalloids to humans and animals can lead to numerous physical, muscular, neurological, nephrological, and diverse degenerative diseases and dysfunctions, including multiple sclerosis, muscular dystrophy, Parkinson's and Alzheimer's diseases, cardiovascular disorders, and several others. Recognized heavy metals such as lead, mercury, arsenic, cadmium, thallium, and hexavalent chromium are known for enormous toxicity. The immediate vital signs of acute heavy metal exposure include nausea, vomiting, diarrhea, and acute abdominal pain. Mercury has been identified as the most toxic heavy metal, and mercury poisoning is known as acrodynia or pink disease. Similarly, lead, another toxic heavy metal, was at one time an integral part of painting. Metal Toxicology Handbook further explains and discusses the varying attributes of metals, discussing toxicity, safety, and proper human utilization of metals. Beginning with a broad overview of metals, metalloids, redox biology, and neurodegeneration and going further into the roles, benefits, and toxicity of metals with each section, the text contains 28 chapters from eminent researchers and scientists in their respective fields and is a must-have for anyone researching the potential toxicity in metals. Key Features Discusses the pathology of metal toxicity Highlights the benefits of metals Explains the mechanism and salient features of restoring metabolic homeostasis Highlights dose-dependent beneficial and adverse effects of vanadium safety and toxicity The initial introductory section provides a broad overview of metals, metalloids, redox biology, and neurodegeneration. The second section discusses the pathology of metal toxicity in two chapters, while the third section highlights the mechanism and salient features of restoring metabolic homeostasis in two chapters. The fourth section demonstrates the aspect of radionuclides toxicity. In a change of pace, the fifth section discusses the benefits of metals in four chapters. The sixth section, titled "Toxic Manifestations by Diverse Heavy Metals and Metalloids," provides fourteen chapters that discuss the toxicological mechanism and manifestation of individual metals. The editors have crafted a commentary titled "A Treatise on Metal Toxicity" and summarized a vivid scenario of metal toxicity and its consequences.

The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and management, Animal-centric Care and Management: Enhancing Refinement in Biomedical Research takes Russell and Burch's definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals. The team of expert authors, from the fields of laboratory animal science, ethology, biology as well as animal training, provide ideas for creating housing conditions and handling procedures that induce, to the best of current abilities and knowledge, a long-term positive state of mind in the animals under our care. This book is written for animal caretakers, animal health technicians, researchers, animal facility managers, laboratory animal veterinarians, and anyone who engages in work with living experimental animals or is interested in the continuous improvement of laboratory animal welfare. This interdisciplinary guide will act as a catalyst, resulting in multiple viewpoints and fields collaborating to optimize laboratory animal welfare.

The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and management, Animal-centric Care and Management: Enhancing Refinement in Biomedical Research takes Russell and Burch's definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals. The team of expert authors, from the fields of laboratory animal science, ethology, biology as well as animal training, provide ideas for creating housing conditions and handling procedures that induce, to the best of current abilities and knowledge, a long-term positive state of mind in the animals under our care. This book is written for animal caretakers, animal health technicians, researchers, animal facility managers, laboratory animal veterinarians, and anyone who engages in work with living experimental animals or is interested in the continuous improvement of laboratory animal welfare. This interdisciplinary guide will act as a catalyst, resulting in multiple viewpoints and fields collaborating to optimize laboratory animal welfare.

Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy, and significant areas of accomplished or needed endeavor in the total field of xenobiotics in any segment of the environment, as well as toxicological implications.

Microbe-Assisted Phytoremediation of Environmental Pollutants: Recent Advances and Challenges provides comprehensive information on the principles and practical knowledge of microbe-assisted phytoremediation of organic and inorganic pollutants for environmental safety. This book describes the physiological, biochemical, microbiological, and molecular basis of microbe-assisted phytoremediation and contains many relevant topics to fill the gaps in developing an understanding of microbe-assisted phytoremediation of environmental pollutants. The book provides state-of-the-art knowledge on fundamental, practical, and purposeful utilization of plant-associated bacteria (plant growth-promoting rhizobacteria [PGPR] and endophytes) and arbuscular mycorrhizal fungi for plant-growth promotion and enhanced phytoremediation of environmental pollutants in the contaminated matrix. Features: Provides a state-of-the-art overview of microbe-assisted phytoremediation Emphasizes the roles of PGPR, endophytes, and mycorrhizal fungi in assisted phytoremediation Elucidates biochemical and molecular mechanisms of microbe-assisted phytoremediation Details field studies and success stories of microbe-assisted phytoremediation Explores advances, challenges, and future directions in microbe-assisted phytoremediation The book serves as a valuable resource for researchers, ecotoxicologists, environmental scientists and engineers, environmental microbiologists and biotechnologists, environmental health and risk scientists, environmental science managers and administrators, remediation practitioners, environmental policymakers, and students at the postgraduate and doctoral levels in the relevant fields who wish to work on microbe-assisted phytoremediation of pollutants for environmental safety and sustainability.

Crisis Management of Chronic Pollution: Contaminated Soil and Human Health deals with a long term pollution problem, generated by the former use of organochlorine pesticides. Through a case study of the chlordecone pollution in the French West Indies, the authors illustrate a global and systemic mobilization of research institutions and public services. This "management model", together with its major results, the approach and lessons to be learned, could be useful to other situations. This book gathers all the works that have been carried out over the last ten years or more and links them to decision makers' actions and stakeholders' expectations. This reference fills a gap in the literature on chronic pollution.

Building on the success of its popular predecessor, the second edition of Ecotoxicology of Amphibians and Reptiles presents newly available findings on the species that are important environmental indicators. This new edition covers nearly twice as many topics as the first, including recent developments in the ecotoxicology of amphibians and reptiles, the current status of these animals, and intrinsic factors that affect their susceptibility to contaminants. The book also provides the latest information on specific groups of contaminants and their effects and body burdens in herpetafauna. After a review of how contaminants interact with other ecological factors, the text explores concerns for the future. New in the second edition: New research on the effects of pesticides, heavy metals, endocrine disrupting chemicals, and UVB Increased focus on the effects of contaminants rather than merely reporting residue information A synthesis of information on atrazine and its effects on gonads at low concentrations Coverage of the potentially alarming new cadre of chemicals that have recently or are about to come on the market for which there is very little or no information Important advances in surveying and monitoring One of the major factors behind the writing of the first edition was the worldwide phenomenon of declining amphibian populations. Although this decline has not abated, the breadth of research into its causes has expanded significantly. With chapter contributors carefully selected by the team of editors as leaders in their fields, this book provides an authoritative compendium of the most recent information on effects and residues coupled with a syntheses of what these numbers mean to science and policy.

Examines endocrine toxicologya (TM)s increased importance in environmental safety issues due to legislative directives established over the past ten years.

With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system.

Covering all principal areas of EPA concern, Endocrine Toxicology, Third Edition provides:

• putative endocrine disruptors and mechanisms of endocrine toxicity
• the history and status of the regulatory process
• mechanisms of toxic effects in various hormonal systems
• comparisons of the endocrine responses in humans, livestock, and wildlife
• testing methods in mammalian, fish, avian, and amphibian models
• valuable insight into the approaches of various personnel in the field, including: government officials who make and oversee policy; scientists in charge of development and validation of testing methods; basic researchers who identify toxic mechanisms; and manufacturers responsible for environmentally benign product certification