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Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Chemical engineering

Tellurite Glasses Handbook - Physical Properties and Data, Second Edition (Paperback, 2nd edition): Raouf A.H. El-Mallawany Tellurite Glasses Handbook - Physical Properties and Data, Second Edition (Paperback, 2nd edition)
Raouf A.H. El-Mallawany
R2,681 Discovery Miles 26 810 Ships in 12 - 17 working days

Tellurite Glasses Handbook: Physical Properties and Data, Second Edition covers the current dominant physical properties of this prototype glass system. Focusing on thermal, elastic, acoustic, electrical, and optical properties, this second edition incorporates the latest scientific data and up-to-date applications of tellurite glass. New Topics in the Second Edition Nanocomposites Three-dimensional structural models Novel glass-forming systems Innovative ways to combine all physical properties simultaneously, creating new points for research Addressing the knowledge gap among physicists, chemists, and material scientists in their understanding of tellurite glasses' properties, this edition gathers essential thermal, mechanical, electrical, and optical data in one source. It emphasizes the physics and technology of twenty-first century processing, fabrication, and behavior of tellurite glass and glass-ceramic materials. It is the first and only comprehensive source of physical constants and properties of these unique noncrystalline solids. After an introductory chapter on the composition of tellurite glasses, the book explores elastic, acoustic, thermal, electrical, and optical properties. Each chapter includes basic theories on a particular physical property, related experimental techniques, and representative data. The book uniquely presents a compilation of scientific data from the last 60 years as well as practical and strategic applications based on the properties of tellurite glasses.

Computational Techniques for Process Simulation and Analysis Using MATLAB (R) (Paperback): Niket S. Kaisare Computational Techniques for Process Simulation and Analysis Using MATLAB (R) (Paperback)
Niket S. Kaisare
R2,231 Discovery Miles 22 310 Ships in 12 - 17 working days

MATLAB (R) has become one of the prominent languages used in research and industry and often described as "the language of technical computing". The focus of this book will be to highlight the use of MATLAB (R) in technical computing; or more specifically, in solving problems in Process Simulations. This book aims to bring a practical approach to expounding theories: both numerical aspects of stability and convergence, as well as linear and nonlinear analysis of systems. The book is divided into three parts which are laid out with a "Process Analysis" viewpoint. First part covers system dynamics followed by solution of linear and nonlinear equations, including Differential Algebraic Equations (DAE) while the last part covers function approximation and optimization. Intended to be an advanced level textbook for numerical methods, simulation and analysis of process systems and computational programming lab, it covers following key points * Comprehensive coverage of numerical analyses based on MATLAB for chemical process examples. * Includes analysis of transient behavior of chemical processes. * Discusses coding hygiene, process animation and GUI exclusively. * Treatment of process dynamics, linear stability, nonlinear analysis and function approximation through contemporary examples. * Focus on simulation using MATLAB to solve ODEs and PDEs that are frequently encountered in process systems.

Computational Techniques for Process Simulation and Analysis Using MATLAB (R) (Hardcover): Niket S. Kaisare Computational Techniques for Process Simulation and Analysis Using MATLAB (R) (Hardcover)
Niket S. Kaisare
R3,592 Discovery Miles 35 920 Ships in 12 - 17 working days

MATLAB (R) has become one of the prominent languages used in research and industry and often described as "the language of technical computing". The focus of this book will be to highlight the use of MATLAB (R) in technical computing; or more specifically, in solving problems in Process Simulations. This book aims to bring a practical approach to expounding theories: both numerical aspects of stability and convergence, as well as linear and nonlinear analysis of systems. The book is divided into three parts which are laid out with a "Process Analysis" viewpoint. First part covers system dynamics followed by solution of linear and nonlinear equations, including Differential Algebraic Equations (DAE) while the last part covers function approximation and optimization. Intended to be an advanced level textbook for numerical methods, simulation and analysis of process systems and computational programming lab, it covers following key points * Comprehensive coverage of numerical analyses based on MATLAB for chemical process examples. * Includes analysis of transient behavior of chemical processes. * Discusses coding hygiene, process animation and GUI exclusively. * Treatment of process dynamics, linear stability, nonlinear analysis and function approximation through contemporary examples. * Focus on simulation using MATLAB to solve ODEs and PDEs that are frequently encountered in process systems.

Macroporous Polymers - Production Properties and Biotechnological/Biomedical Applications (Paperback): Bo Mattiasson, Ashok... Macroporous Polymers - Production Properties and Biotechnological/Biomedical Applications (Paperback)
Bo Mattiasson, Ashok Kumar, Igor Yu Galeaev
R2,232 Discovery Miles 22 320 Ships in 12 - 17 working days

Macroporous polymers are rapidly becoming the material of choice for many tissue engineering, bioseparation, and bioprocessing applications. However, while important information is scattered about in many different publications, none, to date, have drawn this information together in user-friendly format, until now. Meeting the need for an accessible, organized resource, Macroporous Polymers: Production Properties and Biotechnological/Biomedical Applications supplies a systematic presentation of the production, characterization, and application of these polymers. The text discusses traditional methods of production, including phase separation polymerization, leaching, foaming, and double emulsion as well as emerging methods such as cryogelation. The chapters also detail the various applications of macroporous gels for the separation of biomolecules and for the cultivation of mammalian cells in bioreactors and for tissue engineering. The book underscores existing and potential problems while providing a solid background on which to base the evaluation of the scientific and commercial value of new developments. The editors bring together different viewpoints, summarize state-of-the-art achievement, and cover applications in biotechnology, downstream processing, and biomedicine. They have collected the latest research and molded it into a cohesive reference, closing the gap between macromolecular design and production of these gels/polymers and their possible applications. With the intensity of development in this area likely to increase, the foundation provided by this book can help you meet the challenges inherent in the development of new and better materials for new and better applications.

Hazard Assessment Of Ethylene Oxide (Hardcover): Leon Golberg Hazard Assessment Of Ethylene Oxide (Hardcover)
Leon Golberg
R2,788 Discovery Miles 27 880 Ships in 12 - 17 working days

Hazard assessment of EO has involved consideration of the chemical composition, characteristics, and reactivity of this material. Teratogenic effects of EO are only seen under extreme conditions that render the result questionable. Reproductive effects or minor severity occur only at high levels of exposer. Epidemiological and other studies of occupational exposure to EO in men and women have revealed no substantial evidence of potential to produce cancer in the work place.

Management of Hazardous Energy - Deactivation, De-Energization, Isolation, and Lockout (Paperback): Thomas Neil McManus Management of Hazardous Energy - Deactivation, De-Energization, Isolation, and Lockout (Paperback)
Thomas Neil McManus
R1,784 Discovery Miles 17 840 Ships in 12 - 17 working days

Hazardous energy present in systems, machines, and equipment has injured, maimed, and killed many workers. One serious injury can stop the growth of your business in its tracks. Management of Hazardous Energy: Deactivation, De-Energization, Isolation, and Lockout provides the practical tools needed to assess hazardous energy in equipment, machines, and systems, and covers how to manage hazardous energy through elimination or control in order to ensure worker safety and regulatory compliance. Written in plain English with a minimum of jargon, this book provides safety professionals with the knowledge they need to interact with specialists, designers, and engineers to ensure that appropriate and necessary protocols and safety practices and tools are put into place for assessing the dangers and steps taken to eliminate or control exposure to hazardous energy when needed. Approaching the subject from the bottom up, the author starts at the workplace level, to ensure that the right actions happen for the right reasons. The book explains a protocol for describing the flow of energy, including transformation and/or storage; for capturing the logic of decisions about control, including failure analysis and contingency planning; and ultimately for creating procedures that are technically sound and defensible. Creating simple procedures for ensuring worker safety and regulatory compliance, the book offers US and international strategies for hazardous energy management and contains examples to illustrate the application of concepts to specific areas.

Metal-Catalyzed Polymerization - Fundamentals to Applications (Hardcover): Samir Chikkali, Ashootosh V. Ambade, Bas De Bruin,... Metal-Catalyzed Polymerization - Fundamentals to Applications (Hardcover)
Samir Chikkali, Ashootosh V. Ambade, Bas De Bruin, Michael Shaver
R4,295 Discovery Miles 42 950 Ships in 12 - 17 working days

The proposed book focusses on metal mediated/catalyzed "controlled/living radical polymerization" (CRP/LRP) methods. It surveys a wide variety of catalyzed polymerization reactions, making it essentially a "one stop" review in the field. A significant contribution to polymer science is "metathesis polymerization" discovered by Grubbs and others. The book will cover various metathesis polymerization methods and implications in polymer industry.

Physics of Charged Macromolecules - Synthetic and Biological Systems (Hardcover, New title): Murugappan Muthukumar Physics of Charged Macromolecules - Synthetic and Biological Systems (Hardcover, New title)
Murugappan Muthukumar
R2,139 Discovery Miles 21 390 Ships in 12 - 17 working days

A concise introduction to the physics of charged macromolecules, from the basics of electrostatics to cutting-edge modern research developments. This accessible book provides a clear and intuitive view of concepts and theory, and features appendices detailing mathematical methodology. Supported by results from real-world experiments and simulations, this book equips the reader with a vital foundation for performing experimental research. Topics include living matter and synthetic materials including polyelectrolytes, polyzwitterions, polyampholytes, proteins, intrinsically disordered proteins, and DNA/RNA. Serving as a gateway to the growing field of charged macromolecules and their applications, this concept-driven book is a perfect guide for students beginning their studies in charged macromolecules, providing new opportunities for research and discovery.

Hydrogenation with Low-Cost Transition Metals (Paperback): Jacinto Sa, Anna Srebowata Hydrogenation with Low-Cost Transition Metals (Paperback)
Jacinto Sa, Anna Srebowata
R2,186 Discovery Miles 21 860 Ships in 12 - 17 working days

Hydrogenation with Low-Cost Transition Metals describes recent developments in the preparation of catalysts and their catalytic abilities in chemoselective hydrogenation for the production of fine chemicals and pharmaceutical compounds. Emphasizing the use of low-cost metals (Cu, Ni, Fe, and Ag) that are often present in the form of nanoparticles, the book provides valuable reaction mechanism schemes, engineering solutions, and perspective for the field.

Nanocomposite Membrane Technology - Fundamentals and Applications (Paperback): P. K. Tewari Nanocomposite Membrane Technology - Fundamentals and Applications (Paperback)
P. K. Tewari
R3,548 Discovery Miles 35 480 Ships in 12 - 17 working days

Nanocomposite Membrane Technology: Fundamentals and Applications is the first book to deliver an extensive exploration of nanocomposite membrane technology. This groundbreaking text offers an eloquent introduction to the field as well as a comprehensive overview of fundamental aspects and application areas. Approaching the subject from the materials point of view, this book: Discusses the history, synthesis, and characterization of nanocomposite membranes Examines water treatment, gas separation, and biomedical applications Addresses health, environmental, safety, and societal implications Considers processing challenges, including scalability issues Provides case studies of real-world implementations Nanocomposite Membrane Technology: Fundamentals and Applications covers each topic with enough clarity and detail to be a valuable source of information for beginners and experts alike. Thus, this book is the guide of choice for scientists and engineers in both industry and academia.

Statistical Optimization of Biological Systems (Paperback): Tapobrata Panda, Thomas Theodore, R. Arunkumar Statistical Optimization of Biological Systems (Paperback)
Tapobrata Panda, Thomas Theodore, R. Arunkumar
R2,108 Discovery Miles 21 080 Ships in 12 - 17 working days

A number of books written by statisticians address the mathematical optimization of biological systems, but do not directly address statistical optimization. Statistical Optimization of Biological Systems covers the optimization of bioprocess systems in its entirety, devoting much-needed attention to the experimental optimization of biological systems using statistical techniques. Employing real-life bioprocess optimization problems and their solutions as examples, this book: Describes experimental design from identifying process variables to selecting a screening design, applying response surface methodology, and conducting regression modeling Demonstrates the statistical analysis and optimization of different experimental designs, the results of which are used to establish important variables and optimum settings Details the optimization techniques employed to determine optimum levels of the process variables for both single- and multiple-response systems Discusses important experimental designs, such as evolutionary operation programs and Taguchi's designs Delineates the concept of hybrid experimental design using the essence of a genetic algorithm Statistical Optimization of Biological Systems examines the complex nature of biological systems, the need for optimization, and the rationale of statistical and non-statistical optimization methods. More importantly, the book explains how to successfully apply mathematical and statistical techniques to the optimization of biological systems.

Patient Handling in the Healthcare Sector - A Guide for Risk Management with MAPO Methodology (Movement and Assistance of... Patient Handling in the Healthcare Sector - A Guide for Risk Management with MAPO Methodology (Movement and Assistance of Hospital Patients) (Hardcover)
Olga Menoni, Natale Battevi, Silvia Cairoli
R5,339 Discovery Miles 53 390 Ships in 12 - 17 working days

Hospital staff and caregivers are regularly exposed to biomechanical overload risk, particularly at spine and shoulder level a risk factor that will continue to rise with the progressive aging of the population. Patient Handling in the Healthcare Sector: A Guide for Risk Management with MAPO Methodology (Movement and Assistance of Hospital Patients) details the analysis of patient handling risk using the MAPO method in different areas of healthcare and helps you develop strategies to mitigate them. Focusing on the organization of work, this approach gives you the tools to: Rapidly analyse the problem Rapidly identify solutions Effectively monitor the results of preventive actions One of the special features of this approach is that it employs tools that allow you to allocate financial resources to estimate what investments are needed to achieve specific results. This means taking the decision-making process out of the hands of ergonomics experts and putting it into those of healthcare facility administrators.

Introduction to Chemical Reactor Analysis (Hardcover, 2nd edition): R.E. Hayes, J P Mmbaga Introduction to Chemical Reactor Analysis (Hardcover, 2nd edition)
R.E. Hayes, J P Mmbaga
R5,389 Discovery Miles 53 890 Ships in 12 - 17 working days

Introduction to Chemical Reactor Analysis, Second Edition introduces the basic concepts of chemical reactor analysis and design, an important foundation for understanding chemical reactors, which play a central role in most industrial chemical plants. The scope of the second edition has been significantly enhanced and the content reorganized for improved pedagogical value, containing sufficient material to be used as a text for an undergraduate level two-term course. This edition also contains five new chapters on catalytic reaction engineering.Written so that newcomers to the field can easily progress through the topics, this text provides sufficient knowledge for readers to perform most of the common reaction engineering calculations required for a typical practicing engineer. The authors introduce kinetics, reactor types, and commonly used terms in the first chapter. Subsequent chapters cover a review of chemical engineering thermodynamics, mole balances in ideal reactors for three common reactor types, energy balances in ideal reactors, and chemical reaction kinetics. The text also presents an introduction to nonideal reactors, and explores kinetics and reactors in catalytic systems.The book assumes that readers have some knowledge of thermodynamics, numerical methods, heat transfer, and fluid flow. The authors include an appendix for numerical methods, which are essential to solving most realistic problems in chemical reaction engineering. They also provide numerous worked examples and additional problems in each chapter. Given the significant number of chemical engineers involved in chemical process plant operation at some point in their careers, this book offers essential training for interpreting chemical reactor performance and improving reactor operation. What's New in This Edition: Five new chapters on catalytic reaction engineering, including various catalytic reactions and

Deterministic Flexibility Analysis - Theory, Design, and Applications (Hardcover): Chuei-Tin Chang, Vincentius Surya Kurnia Adi Deterministic Flexibility Analysis - Theory, Design, and Applications (Hardcover)
Chuei-Tin Chang, Vincentius Surya Kurnia Adi
R4,894 Discovery Miles 48 940 Ships in 12 - 17 working days

Traditionally, design and control decisions are made in sequential stages over the life cycle of a chemical plant. In the design phase, the optimal operating conditions and the corresponding material and energy balance data are established mainly on the basis of economic considerations. In the subsequent step, the control systems are configured to maintain the key process conditions at the fixed nominal values. Because it is often desirable to address the operability issues at the earliest possible stage before stipulation of control schemes, the systematic incorporation of flexibility analysis in process synthesis and design has received considerable attention in recent years. This book focuses to a large extent on computation and implementation methods of deterministic performance measures, i.e., the steady-state, volumetric, dynamic and temporal flexibility indices, in various applications. The formal definitions of several available performance indices, their mathematical formulations, and the corresponding algorithms and codes are provided in sufficient detail to facilitate implementation. To show the utility of flexibility analyses, the book presents several practical case studies including membrane modules and heat-exchanger networks, solar-driven membrane distillation desalination systems, and hybrid power generation systems. It also includes MATLAB and GAMS codes.

Practical Guide to Industrial Safety - Methods for Process Safety Professionals (Hardcover): Nicholas P. Cheremisinoff Practical Guide to Industrial Safety - Methods for Process Safety Professionals (Hardcover)
Nicholas P. Cheremisinoff
R6,998 Discovery Miles 69 980 Ships in 12 - 17 working days

This practical reference concentrates on high-risk health and safety concerns found in the chemical, petroleum, laboratory, and manufacturing industries, particularly inhalation hazards and direct chemical exposure-emphasizing risks regulated by the Occupational Health and Safety Administration (OSHA). Guides safety specialists in managing operations, implementing accident prevention principles, and applying emergency response practices Describing accident investigation principles, assessment of confined space operations, and National Fire Protection Association (NFPA) hazard ratings, Practical Guide to Industrial Safety examines chemical dangers in the production of polymers, rubber products, sulfuric and phosphoric acids, and insecticides techniques in the diagnosis, management, measurement, and control of indoor air quality personal protective equipment for the eyes, hands, face, head, and feet when handling chemicals, asbestos, and other synthetic mineral fibers precautionary measures for controlled substances, liquefied gases, flammables, combustibles, corrosives, and ethers in the laboratory concepts of industrial hygiene methods for the prevention of inhalation hazards in refineries and more Offering a comprehensive compilation of useful Web sites for a variety of health, safety, and emergency issues, Practical Guide to Industrial Safety is an effective reference for process safety professionals; safety, health, chemical, industrial, and environmental process safety engineers and consultants; regulatory and occupational safety officials; and upper-level undergraduate and graduate students in these disciplines.

Applied Parameter Estimation for Chemical Engineers (Hardcover): Peter Englezos, Nicolas Kalogerakis Applied Parameter Estimation for Chemical Engineers (Hardcover)
Peter Englezos, Nicolas Kalogerakis
R7,617 Discovery Miles 76 170 Ships in 12 - 17 working days

This book determines adjustable parameters in mathematical models that describe steady state or dynamic systems, presenting the most important optimization methods used for parameter estimation. It focuses on the Gauss-Newton method and its modifications for systems and processes represented by algebraic or differential equation models.

Linking Aquatic Exposure and Effects - Risk Assessment of Pesticides (Paperback): Theo C. Brock Linking Aquatic Exposure and Effects - Risk Assessment of Pesticides (Paperback)
Theo C. Brock
R2,220 Discovery Miles 22 200 Ships in 12 - 17 working days

Time-variable exposure profiles of pesticides are more often the rule than exception in the surface waters of agricultural landscapes. There is, therefore, a need to adequately address the uncertainties arising from time-variable exposure profiles in the aquatic risk assessment procedure for pesticides. Linking Aquatic Exposure and Effects: Risk Assessment of Pesticides provides guidance and recommendations for linking aquatic exposure and ecotoxicological effects in the environmental assessment of agricultural pesticides. Leading international scientists share their expertise in aquatic exposure assessment, aquatic ecotoxicology, and the risk assessment and management of plant protection products. The book incorporates the tools and approaches currently available for assessing the environmental risks of time-variable exposure profiles of pesticides. It also discusses the science behind these techniques. This volume covers the extrapolation techniques, including models that address the environmental fate, toxicokinetics, toxicodynamics, and ecological effects, for performing accurate aquatic environmental risk assessments of pesticides. It explains how to link aquatic exposure and effects in the risk assessment procedure for plant protection products.

Occupational Health and Safety in the Food and Beverage Industry (Hardcover): Ebrahim Noroozi, Ali R. Taherian Occupational Health and Safety in the Food and Beverage Industry (Hardcover)
Ebrahim Noroozi, Ali R. Taherian
R3,538 Discovery Miles 35 380 Ships in 12 - 17 working days

The text highlights the importance of achieving a safe and healthy working environment in the food and beverage processing industry. It provides information on food and beverage manufacturing disease, injury management, safer steps for employees to get back to work, discusses food security, safety, biosecurity, defense food safety, and quality including food adulteration. * Discusses fundamentals of occupational health and safety in the food and beverage industry. * Highlight standards and legislations as related to occupational health and safety for food and beverage processing sectors. * Covers hazards, elements, accident prevention, various hazards present in food and beverage sectors, and their disease and injury management. * Explores ethical issues in agri-food processing sectors and their effects on sustainability. * Introduces importance, organization, and management for food and beverage processing sectors to prevent losses. The text is primarily written for professionals in the fields of occupational health and safety, food engineering, chemical engineering, and process engineering.

Handbook of Chemicals and Safety (Paperback): T. S. S. Dikshith Handbook of Chemicals and Safety (Paperback)
T. S. S. Dikshith
R2,190 Discovery Miles 21 900 Ships in 12 - 17 working days

A host of chemical substances have become essential parts of human activities and requirements for societal development. Any kind of misuse and/or negligence in handling these substances can cause health disorders, poisoning, and fatalities among unprotected workers and members of the public exposed to contaminated food, water, and air. Carefully organized for ease of use, Handbook of Chemicals and Safety provides a tool for the management of a range of chemical substances commonly used, handled, stored, transported, and disposed of as wastes. Written in an accessible style with just the right amount of technical rigor, the book covers: General fundamentals and specific hazards and effects of chemical substances The basics of exposures and responses to chemical substances in the work environment Toxic responses in different body systems General perspective on the problem of chemical exposures and the possible health effects The author includes substances such as industrial solvents, pesticides, metals, air pollutants, toxic gases, drugs, and other items. He supplies the chemical abstract system (CAS) number, IUPAC name, molecular formula, synonyms and trade names, use and exposure, toxicity and health effects, and carcinogen factors. He also includes information on exposure limits, methods of proper storage, and waste disposal. An important reference on exposure to different categories of chemical substances, the book stresses the importance of preparedness in any safety program. Taking a broad and interdisciplinary approach to chemicals and workplace safety, it provides guidance on the judicious management of chemical substances.

Ecological Models for Regulatory Risk Assessments of Pesticides - Developing a Strategy for the Future (Hardcover): Pernille... Ecological Models for Regulatory Risk Assessments of Pesticides - Developing a Strategy for the Future (Hardcover)
Pernille Thorbek, Valery E. Forbes, Fred Heimbach, Udo Hommen, Hans-Hermann Thulke, …
R5,480 Discovery Miles 54 800 Ships in 12 - 17 working days

Bringing together more than thirty influential regulators, academics, and industry scientists, Ecological Models for Regulatory Risk Assessments of Pesticides: Developing a Strategy for the Future provides a coherent, science-based view on ecological modeling for regulatory risk assessments. It discusses the benefits of modeling in the context of registrations, identifies the obstacles that prevent ecological modeling being used routinely in regulatory submissions, and explores the actions needed to overcome these obstacles. The book focuses on the following issues: Uncertainties in the process of model development, such as design, analysis, documentation, and communication The availability of data and background information needed for optimal modeling The limited knowledge of modeling The lack of confidence in the outcome of ecological models and their reliability in pesticide risk assessment It also suggests future solutions to these challenges, including: A guidance document on the modeling process Case studies that show how ecological models can provide reliable ecologically relevant risk assessments Training the people who generate or evaluate results obtained by ecological models Focusing on ecological models, such as unstructured population models, stage-structured matrix models, and individual- or agent-based models, this volume helps regulatory authorities, manufacturers, and scientists assess the risk of plant protection products in nontarget organisms. Armed with this knowledge, readers will better understand the challenges of using ecological modeling in the regulatory process.

3D Cell-Based Biosensors in Drug Discovery Programs - Microtissue Engineering for High Throughput Screening (Paperback):... 3D Cell-Based Biosensors in Drug Discovery Programs - Microtissue Engineering for High Throughput Screening (Paperback)
William S. Kisaalita
R2,213 Discovery Miles 22 130 Ships in 12 - 17 working days

Advances in genomics and combinatorial chemistry during the past two decades inspired innovative technologies and changes in the discovery and pre-clinical development paradigm with the goal of accelerating the process of bringing therapeutic drugs to market. Written by William Kisaalita, one of the foremost experts in this field, 3D Cell-Based Biosensors in Drug Discovery Programs: Microtissue Engineering for High Throughput Screening provides the latest information - from theory to practice - on challenges and opportunities for incorporating 3D cell-based biosensors or assays in drug discovery programs. The book supplies a historical perspective and defines the problem 3D cultures can solve. It also discusses how genomics and combinatorial chemistry have changed the way drug are discovered and presents data from the literature to underscore the less-than-desirable pharmaceutical industry performance under the new paradigm. The author uses results from his lab and those of other investigators to show how 3D micro environments create cell culture models that more closely reflect normal in vivo-like cell morphology and function. He makes a case for validated biomarkers for three-dimensionality in vitro and discusses the advantages and disadvantages of promising tools in the search of these biomarkers. The book concludes with case studies of drugs that were abandoned late in the discovery process, which would have been discarded early if tested with 3D cultures. Dr. Kisaalita presents evidence in support of embracing 3D cell-based systems for widespread use in drug discovery programs. He goes to the root of the issue, establishing the 3D cell-based biosensor physiological relevance by comparing 2D and 3D culture from genomic to functional levels. He then assembles the bioengineering principles behind successful 3D cell-based biosensor systems. Kisaalita also addresses the challenges and opportunities for incorporating 3D cell-based biosensors or cultures in current discovery and pre-clinical development programs. This book makes the case for widespread adoption of 3D cell-based systems, rendering their 2D counterparts, in the words of Dr. Kisaalita "quaint, if not archaic" in the near future.

Ion Exchange and Solvent Extraction - A Series of Advances, Volume 19 (Paperback): Bruce A Moyer Ion Exchange and Solvent Extraction - A Series of Advances, Volume 19 (Paperback)
Bruce A Moyer
R2,254 Discovery Miles 22 540 Ships in 12 - 17 working days

The growth in the world's nuclear industry, motivated by peaking world oil supplies, concerns about the greenhouse effect, and domestic needs for energy independence, has resulted in a heightened focus on the need for next-generation nuclear fuel-cycle technologies. Ion Exchange and Solvent Extraction: A Series of Advances, Volume 19 provides a comprehensive look at the state of the science underlying solvent extraction in its role as the most powerful separation technique for the reprocessing of commercial spent nuclear fuel. Capturing the current technology and scientific progress as it exists today and looking ahead to potential developments, the book examines the overall state of solvent extraction in reprocessing, new molecules for increased selectivity and performance, methods for predicting extractant properties, and actinide-lanthanide group separation. The contributors also explore the simultaneous extraction of radionuclides by mixing extractants, the cause and nature of third-phase formation, the effects of radiation on the solvent and its performance, analytical techniques for measuring process concentrations, new centrifugal contactors for more efficient processing, and new chemistry using novel media. The long-term vision of many professionals in the field entails a proliferation-free nuclear energy economy in which little or no waste is stored or released into the environment and all potential energy values in spent nuclear fuel are recycled. This text opens a window on that possibility, offering insight from world leaders on the cutting edge of nuclear research.

Polymer Thermodynamics - Blends, Copolymers and Reversible Polymerization (Paperback): Kal Renganathan Sharma Polymer Thermodynamics - Blends, Copolymers and Reversible Polymerization (Paperback)
Kal Renganathan Sharma
R2,354 Discovery Miles 23 540 Ships in 12 - 17 working days

Polymer Thermodynamics: Blends, Copolymers and Reversible Polymerization describes the thermodynamic basis for miscibility as well as the mathematical models used to predict the compositional window of miscibility and construct temperature versus volume-fraction phase diagrams. The book covers the binary interaction model, the solubility parameter approach, and the entropic difference model. Using equation of state (EOS) theories, thermodynamic models, and information from physical properties, it illustrates the construction of phase envelopes. The book presents nine EOS theories, including some that take into account molecular weight effects. Characteristic values are given in tables. It uses the binary interaction model to predict the compositional window of miscibility for copolymer/homopolymer blends and blends of copolymers and terpolymers with common monomers. It discusses Hansen fractional solubility parameter values, six phase diagram types, the role of polymer architecture in phase behavior, and the mathematical framework for multiple glass transition temperatures found in partially miscible polymer blends. The author also illustrates biomedical and commercial applications of nanocomposites, the properties of various polymer alloys, Fick's laws of diffusion and their implications during transient events, and the use of the dynamic programming method in the sequence alignment of DNA and proteins. The final chapter reviews the thermodynamics of reversible polymerization and copolymerization. Polymer blends offer improved performance/cost ratios and the flexibility to tailor products to suit customers' needs. Exploring physical phenomena, such as phase separation, this book provides readers with methods to design polymer blends and predict the phase behavior of binary polymer blends using desktop computers.

Interfacial Electroviscoelasticity and Electrophoresis (Paperback): Jyh-Ping Hsu, Aleksandar M. Spasic Interfacial Electroviscoelasticity and Electrophoresis (Paperback)
Jyh-Ping Hsu, Aleksandar M. Spasic
R2,183 Discovery Miles 21 830 Ships in 12 - 17 working days

In the 20 years since the pilot plant experiments used to develop the concept of electroviscoelasticity, inroads have been made in the understanding of its many related processes. Interfacial Electroviscoelasticity and Electrophoresis meets a massive scientific challenge by presenting deeper research and developments in the basic and applied science and engineering of finely dispersed particles and related systems. Introducing more profound and in-depth treatises related to the liquid-liquid finely dispersed systems (i.e., emulsions and double emulsions), this book describes a new theory developed through the authors' work. These findings are likely to impact other research and applications in a wide array of other fields, considering that the modeling of liquid-liquid interfaces is key to numerous chemical manufacturing processes, including those used for emulsions, suspensions, nanopowders, foams, biocolloids, and plasmas. The authors cover phenomena at the micro, nano, and atto-scales, and their techniques, theory, and supporting data will be of particular interest to nanoscientists, especially with regard to the breaking of emulsions. This groundbreaking book: Takes an interdisciplinary approach to elucidate the momentum transfer and electron transfer phenomena Covers less classical chemical engineering insight and modern molecular and atomic engineering Reviews basic theory of electrokinetics, using the electrophoresis of rigid particles as an example Built around the central themes of hydrodynamic, electrodynamic, and thermodynamic instabilities that occur at interfaces, this book addresses recently developed concepts in the physics, chemistry, and rheological properties of those well-studied interfaces of rigid and deformable particles in homo- and hetero-aggregate dispersed systems. The book also introduces the key phenomenon of electrophoresis, since it is widely adopted either as an analytical tool to characterize the surface properties of colloid-sized particles or in the separation and purification process of both laboratory and industrial scales. The applications and implications of the material presented in the book represent a major contribution to the advanced fundamental, applied, and engineering research of interfacial and colloidal phenomena.

The Role of the Chemist in Automotive Design (Paperback): H. K. Phlegm The Role of the Chemist in Automotive Design (Paperback)
H. K. Phlegm
R2,037 Discovery Miles 20 370 Ships in 12 - 17 working days

From the development of polymers that make cars lighter to fuels that make them run cleaner, the chemist's role in the automotive industry has evolved to be one that is more outside the laboratory than in it. Drawing on the author's 20 years of experience in vehicle design and laboratory experience, The Role of the Chemist in Automotive Design elucidates how the skills of chemists are put to use in the automotive industry and their effect on all phases of design. A glance through the table of contents provides an overview of the issues commonly encountered by chemists in the automotive industry. The author discusses fuels cells, lithium ion batteries, carbon nanotubes, and nickel metal hydride technology, all of which require the technical knowledge of a chemist but cross the lines of various disciplines. He also covers future technology including items such as battery technology, fuel cell membranes, and environmentally friendly plastics such as nylons that use castor oil as a primary component. The book examines environmental concerns such as CARB legislation and how the industry plans to deal with the new legislation with strategies such as Ozone Reduction Catalyst. The increasing technological, environmental, and economic issues facing the auto industry underscores the need for a basic reference that covers technologies that can be used to make vehicle more fuel efficient, environmentally friendly, and cost efficient. Exploring the expanding role chemists will play in future automotive design and technology, this book delineates the areas and technologies that require the technical knowledge of a chemist but that cross the lines of many disciplines.

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