"The Body Multiple" is an extraordinary ethnography of an ordinary disease. Drawing on fieldwork in a Dutch university hospital, Annemarie Mol looks at the day-to-day diagnosis and treatment of atherosclerosis. A patient information leaflet might describe atherosclerosis as the gradual obstruction of the arteries, but in hospital practice this one medical condition appears to be many other things. From one moment, place, apparatus, specialty, or treatment, to the next, a slightly different "atherosclerosis" is being discussed, measured, observed, or stripped away. This multiplicity does not imply fragmentation; instead, the disease is made to cohere through a range of tactics including transporting forms and files, making images, holding case conferences, and conducting doctor-patient conversations.

"The Body Multiple" juxtaposes two distinct texts. Alongside Mol's analysis of her ethnographic material--interviews with doctors and patients and observations of medical examinations, consultations, and operations--runs a parallel text in which she reflects on the relevant literature. Mol draws on medical anthropology, sociology, feminist theory, philosophy, and science and technology studies to reframe such issues as the disease-illness distinction, subject-object relations, boundaries, difference, situatedness, and ontology. In dialogue with one another, Mol's two texts meditate on the multiplicity of reality-in-practice.

Presenting philosophical reflections on the body and medical practice through vivid storytelling, "The Body Multiple" will be important to those in medical anthropology, philosophy, and the social study of science, technology, and medicine.

Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive organs. This volume reviews the latest research and developments in this field.

* Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

Despite great advances in prevention and in improving outcomes, heart disease remains a major source of morbidity and mortality in the Western world and, increasingly, in developing countries. The emotional impact of a diagnosis of heart disease can be significant, often increasing cardiac symptoms such as chest pain or palpitations. This addition to The Facts series stresses the importance and feasibility of primary prevention by appropriate life-style changes, whilst helping the reader to understand and cope with existing heart disease. The book is structured to provide information on topics ranging from basic cardiovascular anatomy and physiology - as needed to understand the various pathologies discussed - to symptoms, clinical situations, investigations and available treatments. Beside medical information, the reader will find practical advice on how to communicate with the cardiologist, and how to prepare for certain tests. A glossary with commonly encountered medical terms is also included. Although targeted mainly at cardiac patients with heart disease and their families, this book will also be useful for paramedics, specialist nurses, support groups, GPs and all those involved in treating heart patients in the community.

The Motoneurone and its Muscle Fibres presents a state-of-the-art summary of knowledge concerning the motoneurones, vital for innervating and commanding skeletal muscles. No muscle action would be possible without motoneurones. These cells are therefore absolutely essential for the execution of normal behaviour and for life support. It is their degeneration that leads to various kinds of motoneurone disease (e.g. ALS) that are often ultimately lethal. However, the study of motoneurones is also important for general insights as to how neurones work, because the motoneurone is probably the best understood kind of nerve cell so far in neuroscience. Motoneurones of the spinal cord were the first type of central nerve cell to be subjected to detailed physiological measurements, and much is known about how their activity is regulated by synapses from other central neurones. For most of the individual neurones within the central nervous system, the precise functional tasks are difficult to define. However, for motoneurones much is now known about their short- and long-term interactions with their main targets, the skeletal muscle fibres. Functions of neurones must be analyzed in relation to the response properties of their target cells. Therefore, this book deals with both, summarizing classical as well as recent knowledge concerning the motoneurone and its muscle fibres. This is the first time that so many aspects of this broad subject matter are treated in one comprehensive monograph.

The first edition of A Guide To Assessments That Work provided a much needed resource on evidence-based psychological assessment. Since the publication of the first edition, a number of advances have been made in the assessment field and a revised diagnostic system for mental disorders has been introduced. These changes are reflected in the second edition and new chapters have been included to cover the use of evidence-based assessment instruments and procedures in clinical practice and the use of evidence-based principles to integrate and interpret assessment data. This volume addresses the assessment of the most commonly encountered disorders or conditions among children, adolescents, adults, older adults, and couples. Strategies and instruments for assessing mood disorders, anxiety and related disorders, couple distress and sexual problems, health-related problems, and many other conditions are reviewed by leading experts. With a focus throughout on assessment instruments that are feasible, psychometrically sound, and useful for typical clinical requirements, this edition features the use of a rating system designed to provide evaluations of a measure's norms, reliability, validity, and clinical utility. Standardized tables summarize this information in each chapter, providing essential information on the most scientifically sound tools available for a range of assessment needs. With its focus on clinically relevant instruments and assessment tasks, this volume provides readers with the essential information for conducting the best evidence-based mental health assessments currently possible.

The Oxford Textbook of Medicine is the foremost international textbook of medicine. Unrivalled in its coverage of the scientific aspects and clinical practice of internal medicine and its subspecialties, it is a fixture in the offices and wards of physicians around the world, as well as being a key resource for medico-legal practitioners. Accessible digitally with regular updates, as well as in print, readers are provided with multiple avenues of access depending on their need and preference. More comprehensive, more authoritative, and more international than any other textbook; Oxford Textbook of Medicine focuses on offering both perspective and practical guidance on clinical management and prevention of disease. Introductory sections focus on the patient experience, medical ethics and clinical decision making, outlining a philosophy which has always characterized the Oxford Textbook of Medicine. It is humane, thought-provoking, and aims to instill in readers an understanding of the role of medicine in society and the contribution it can make to the health of populations, and it does not shy away from discussion of controversial aspects of modern medicine. As always, there is detailed coverage of all areas of internal medicine by the world's very best authors. The Oxford Textbook of Medicine seeks to embody advances in understanding and practice that have arisen through scientific research. The integration of basic science and clinical practice is unparalleled, and throughout the book the implications of research for medical practice are explained. The core clinical medicine sections offer in-depth coverage of the traditional specialty areas. The Oxford Textbook of Medicine has unsurpassed detail on infectious diseases: the most comprehensive coverage to be found in any textbook of medicine. Other sections of note include stem cells and regenerative medicine; inequalities in health; medical aspects of pollution and climate change; travel and expedition medicine; bioterrorism and forensic medicine; pain; medical disorders in pregnancy; nutrition; and psychiatry and drug related problems in general medical practice. The section on acute medicine is designed to give rapid access to information when it is needed quickly. In response to ongoing user feedback there have been substantial changes to ensure that the Oxford Textbook of Medicine continues to meet the needs of its readers. Chapter essentials give accessible overviews of the content and a new design ensures that the textbook is easy to read and navigate. The evidence-base and references continue to be at the forefront of research. New to this edition is that purchasers of the print version of the Oxford Textbook of Medicine sixth edition will have free access on Oxford Medicine Online to all the content plus regular updates for the life of the edition.

This title includes proceedings of the 3rd European Congress on Obesity, Nice, France, 1991.

The Gunner Goggles Series is the first exam prep resource written by a high-scoring peer group of medical students, ensuring the most practical and efficient study guidance. It organizes topics around the USMLE and NBME content outlines for the required shelf exams and features state-of-the-art Augmented Reality (AR) mobile application to extend learning beyond the book. This innovative series features AR opportunities throughout the text for an integrated print-mobile experience that maximizes learning and test preparation. The Gunner Goggle function allows you to scan pages for integrated AR links, unlocking animations, visuals, and 3D models that clarify complex anatomy, conditions, and concepts in a remarkably effective and unique manner. Gunner Goggles Series: Medicine is one of seven authoritative exam preparation guides that use cutting-edge AR technology to fully prepare you for the NBME clinical shelf exams, the USMLE Step 2 Clinical Knowledge (CK) exam, and successful clinical rotations. Topics are organized around the USMLE and NBME content outlines for specific shelf exams, and information is presented in a highly templated, concise manner. The Augmented Reality application allows you to efficiently study and learn using an integrated print-mobile approach. In addition to unlocking animations and other visuals, AR app access also includes additional content, links to provide feedback to the authors, community pages, and more. All test topics are covered in just enough detail to help you hone in on key points you must know for exam success. Unique! Every disease is described by its stem clues (buzzwords that appear in question stems) and prophylactic measures (PPx), mechanism (MoD), diagnostic tests (Dx) and treatment/management principles (Tx/Mgmt) - the four "Physician Tasks" that the NBME requires students to know about each disease. You'll also get real-world tips for your clinical rotations from your peers - information that won't show up on the shelf exam but is ideal for maximum impact when on rounds (knowing the prognosis for a specific disease, for example). Plus . effective study techniques, sample study schedules, tips and tricks to better retain information learned from review questions, and methods to self-generate mnemonics. Edited, written, and crowdsourced by high-performing medical students and residents and reviewed by experts in the field to ensure accuracy, relevancy, and accessibility. Titles in the Gunner Goggles series: Family Medicine . Print ISBN: 978-0-323-51034-9 . e-Book ISBN: 978-0-323-52756-9 Medicine . Print ISBN: 978-0-323-51035-6 . e-Book ISBN: 978-0-323-52758-3 Neurology . Print ISBN: 978-0-323-51036-3 . e-Book ISBN: 978-0-323-52760-6 Ob-Gyn . Print ISBN: 978-0-323-51037-0 . e-Book ISBN: 978-0-323-52768-2 Pediatrics . Print ISBN: 978-0-323-51038-7 . e-Book ISBN: 978-0-323-52763-7 Psychiatry . Print ISBN: 978-0-323-51039-4 e-Book ISBN: 978-0-323-52765-1 Surgery . Print ISBN: 978-0-323-51040-0 . e-Book ISBN: 978-0-323-52767-5

Critical Care Neurology, Part II: Neurology of Critical Illness focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU.

Why do racial and ethnic controversies become attached, as they often do, to discussions of modern genetics? How do theories about genetic difference become entangled with political debates about cultural and group differences in America? Such issues are a conspicuous part of the histories of three hereditary diseases: Tay-Sachs, commonly identified with Jewish Americans; cystic fibrosis, often labeled a "Caucasian" disease; and sickle cell disease, widely associated with African Americans.

In this captivating account, historians Keith Wailoo and Stephen Pemberton reveal how these diseases -- fraught with ethnic and racial meanings for many Americans -- became objects of biological fascination and crucibles of social debate. Peering behind the headlines of breakthrough treatments and coming cures, they tell a complex story: about different kinds of suffering and faith, about unequal access to the promises and perils of modern medicine, and about how Americans consume innovation and how they come to believe in, or resist, the notion of imminent medical breakthroughs.

With Tay-Sachs, cystic fibrosis, and sickle cell disease as a powerful backdrop, the authors provide a glimpse into a diverse America where racial ideologies, cultural politics, and conflicting beliefs about the power of genetics shape disparate health care expectations and experiences.

Over 50% of known flaviviruses have been associated with human disease. The "Flavivirus" genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.
Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research.
* Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions
* Descibes the technologies that have contributed to our current knowledge about the Flaviviruses
* Identifies the major problems faced in understanding the virus-host interactins that result in disease
* An exhaustive compendium of current and past knowledge on the Flavivirus family

Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. An increasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.

Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemic stroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence is reviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing a practical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.

Subcortical Stroke is a new and fully revised edition of Lacunar and Other Subcortical Infarctions (OUP, 1995).

Stroke is one of the most common causes of death and subcortical stroke accounts for 20-30% of all cerebrovascular infarctions. Our understanding of stroke processes in general, and subcortical stroke in particular, has advanced considerably in recent years. Research findings from the fields of neurochemistry, imaging and genetics have provided insight and input to our understanding of this condition, and this new edition provides an opportunity to describe these advances, and to relate the findings to the clinical expression, neural mechanism, prognosis and treatment of subcortical stroke. In addition, new subcortical syndromes such as CADASIL are covered, as is subcortical haemorrhage.

This book presents a comprehensive and authoritative review of the field with contributions from the leading international experts.

Subcortical Stroke is for stroke physicians, neurologists and those researching cerebrovascular diseases.

Infectious disease pandemics are a rising threat in our globalizing world. This agenda-setting collection provides international analysis of the pressing sociological concerns they confront us with, from cross-border coordination of public health governance to geopolitical issues of development and social equity. * Focuses on vital sociological issues raised by resurgent disease pandemics * Detailed analysis of case studies as well as broader, systemic factors * Contributions from North America, Europe and Asia provide international perspective * Bold, agenda-setting treatment of a high-profile topic

The importance of appropriate and effective management of patient with long term chronic conditions cannot be underestimated, and both the Department of Health and the public are expecting much from the improvements and changes outlined in the recently published review by Lord Darzi.
"Case Management of Long Term Conditions" aims to provide all appropriate practitioners across all the professions (nurses, pharmacists, physiotherapists including social care practitioners) who might be involved in delivery of proactive case management with a practical understanding of how their knowledge and skills can be utilised to improve outcomes for people with Chronic Long Term Conditions. The text contains some broad reflections on care and service delivery based on reviews of evidence and views from clinicians in the use of these skills and competencies to deliver improved outcomes for these clients.

Metabolic bone degeneration (osteoporosis) affects millions of people--primarily postmenopausal women--and is directly responsible for debilitating hip, vertebral, and limb fractures in the elderly. Incorporating advances made within just the past five years, The Osteoporotic Syndrome: Detection, Prevention, and Treatment serves as an up-to-date, practical guide to the major clinical aspects of osteoporosis. The text is liberally illustrated with detailed figures.
As a resource for the clinician dealing with metabolic bone degeneration, this book represents an excellent source of information on the diagnosis and day-to-day management of osteoporosis.
Topics covered include
* Therapy with Vitamin D metabolites, sodium fluoride, thiazides, and isoflavones
* Biochemical markers of bone turnover
* Calcium, Vitamin D, and bone metabolism
* Estrogens and tissue selective estrogens for prevention and treatment of osteoporosis
* The effects of osteoporosis on orthopaedic surgery
* The therapy of glucocorticoid bone disease
* Effects of aging on bone structure and metabolism
* Management of osteoporotic patients in our health care delivery system
* The genetics of osteoporosis
* Bisphosphonate therapy for osteoporosis
* Calcitonin
* Bone mass measurement techniques in clinical practice
* Osteoporosis and the bone biopsy

Nitric oxide research has emerged as one of the most important areas in bone and joint diseases. First published in 1998, this book draws together knowledge on the actions of this mediator and its role in such common diseases as arthritis and osteoporosis. It introduces the basic biology and biochemistry of nitric oxide, the immune response and bone biology. It reviews in depth the facts we know today and the future promise of this exciting area of research. The book will give scientists and clinicians a unique insight into this increasingly important area. It also emphasises potential treatments which exploit our understanding of the role of nitric oxide in bone and joint disease.

The overall objective of this book is to provide standards for the knowledge, skills, and attitudes expected of all hospitalists and to provide a framework for ongoing professional and curriculum development for learners at all levels. The framework is intended for use by hospital medicine program directors, directors of medical student clerkships, residency programs, fellowships, and continuing medical education, as well as other educators involved in curriculum development. The competencies do not focus on specific content, but rather general learning objectives within the skills, knowledge, and attitudes related to each topic. Attaining competency in the areas defined in these chapters is expected to require post-residency training. This training is most likely to be obtained through a combination of work experience, local mentorship, and engagement in specific educational programs or fellowship. Hospitalists, directors, and educators can create specific instructional activities and methods chosen to reflect the characteristics of the intended learners and context of the practice environment.

Within each section, individual chapters on focused topics provide competencies in three domains of educational outcomes: the Cognitive Domain (Knowledge), the Psychomotor Domain (Skills), and the Affective Domain (Attitudes). To reflect the emphasis of hospital medicine practice on improving healthcare systems, a fourth section entitled Systems Organization and Improvement is also included. An attempt has been made to make the objectives timeless, allowing for creation of curriculum that can be nimble and reactive to new discoveries.

Although the entire document can be a resource for comprehensive program development, each chapter is intended to stand-alone and thus support curriculum development specific to the needs of individual programs.

This book is an introductory text to spinal disorders. Based on the highly successful forerunner to this volume, Practical Orthopaedic Medicine, the book still retains the original philosophy of this text which is to systematically cover all the joints discussing examination, diagnosis and treatment. The full spectrum of therapies is covered with particular emphasis on Maitland's widely practised spinal manipulation techniques - how they are assessed clinically and their role in the management of spinal problems. A complete review of the current literature has been undertaken and a valuable new chapter on the spine in sport has been added. This book will be essential reading for students and practitioners involved in sports medicine, orthopaedic medicine and physiotherapy.

Great American Diseases: Their Effects on the Course of North American History presents medical history as it pertains to the major infectious diseases of North America. The book is designed to provide an interesting and engaging introduction to microbiology, immunology and epidemiology. With the advent of COVID-19, this book will serve as a reference on the history of previous epidemics. The book presents pandemics in an easy-to-read volume and provides concise chapters on the history of a disease, progression of understanding on the pathogen (agent of the disease), and their social ramifications through the history of North America.

This text highlights the value of a team approach to appreciating the commplexity of spinal pain and a range of treatment approaches. Contributions from epidemiology, anatomy, pathology, biomechanics, clinical medicine orthopaedics, chiropractic, osteopathy and physiotherapy are presented. Each section is written by an experienced practitioner and provides a summary of pertinent material, seeking to improve the reader's understanding of the causes of cervical spine pain The volume is part of a series of three books bringing together a multidisciplinary approach to the management of mechanical spinal pain.

Metabolic Bone Disease, Third Edition is the new, expanded edition of the classic text, featuring the latest advancements and research information in this fast-moving field. The Third Edition includes the most up-to-date information on molecular mechanisms, basic biology, pathophysiology, and diagnosis and management strategies of metabolic bone disease.
Key Features
* Edited by "fathers of the field"
* An expanded version of a classic AP text
* Complete coverage of a fast-growing field