This readable text presents findings from the life science experiments conducted during and after space missions. It provides an insight into the space medical community and the real challenges that face the flight surgeon and life science investigator.

Determining the amenability of personality disorders to psychotherapy& mdash;a patient's capacity to benefit from verbal approaches to treatment& mdash;is important in helping clinicians determine the treatability of cases. Michael Stone here shares the factors he has observed over long years of practice that can help practitioners evaluate patients, stressing the amenability of the various disorders to amelioration. By focusing on which patients are likely to respond well to therapeutic intervention and which will prove most resistive, his book will help therapists determine with what kinds of patients they will most likely succeed and with which ones failure is almost a certainty.

Stone establishes the attributes that affect this amenability& mdash;such as the capacity for self-reflection, motivation, and life circumstances& mdash;as guidelines for evaluating patients, then describes borderline and other personality-disordered patients with varying levels of amenability, from high to low. This coverage progresses from patients belonging to the DSM "anxious cluster," along with the depressive-masochistic character and the hysteric character, to patients who demonstrate an intermediate level of amenability to psychotherapy. He introduces the interrelationship between borderline personality disorder and dissociative disorders and discusses treatability among certain patients in Clusters "A" and "C," as well as others with narcissistic, histrionic, depressive disorders. Final chapters address the most severe aberrations of personality and the limitations they impose on the efficacy of therapy. "Personality-Disordered Patients" is filled with practical, clinically focusedinformation. This guideline structured book: Covers all personality disorders-including ones not addressed in the latest DSM such as sadistic, depressive, hypomanic, and irritable-explosive Identifies both attributes necessary for treatability and factors associated with low treatability Pays particular attention to borderline disorders, which represent the most discussed conditions and are among the most challenging to psychotherapists Reviews personality traits whose presence, if intense-even if unaccompanied by a definable personality disorder-creates severe problems for psychotherapy

Numerous case studies throughout the book provide examples that will help therapists determine which of their own patients are most likely to benefit from their efforts and thereby establish their own limits of effectiveness. By alerting practitioners to when therapy is likely to fail, these guidelines can help them avoid the professional disappointment of being unable to reach the most intractable patients.

The subject of medical entomology contin- factors such as insecticide susceptibility, vec- ues to be of great importance. Arthropodborne tor competence, host preference and similar im- diseases such as malaria, yellow fever, dengue portant phenomena. Now, a variety of new and filariasis continue to cause considerable methods are available to study genes, and to human suffering and death. Problems in ani- genetically alter important characteristics in mal production, wildlife and pets of humans vectors as a potential means of controlling hu- caused by arthropods still exact a large eco- man and animal diseases. nomic toll. In the past 2 decades, the invasion Many of the traditional tasks of medical en- of exotic pests and pathogens has presented tomologists continue to be important. Arthro- new problems in several countries, including pod systematics is important because the need the USA. For example, the year 1999 saw the for accurate identification of arthropods is vital invasion of the eastern USA by Aedes japonicus, to an understanding of natural disease cycles. an Asian mosquito, and West Nile virus, a mos- Systematics has been made even more challeng- quito-transmitted African arbovirus related to ing because of the current appreciation of the St. Louis encephalitis virus. number of groups of sibling species among vec- At the same time old and new health prob- tors of important disease pathogens. New mo- lems with arthropods occur, the traditional ap- lecular tools are assisting in separating these proaches to arthropod control have become forms.

From Simon & Schuster, Man and Microbes respected science writer Arno Karlen presents a dramatic panorama of the natural history of disease. Man and Microbes makes clear that infection is a natural and necessary part of life. It shows how the search for food, shelter, and a safer, more prosperous life has altered the environment, changed the dance of adaptation between humans and microbes, and generated new diseases

go beyond standard medical treatment to treat yourself to wellness
Suffering from a serious condition? Do you have questions that your doctor may not have answered-and are you wondering if you're doing everything you possibly can to get and stay well?
Turn to this authoritative, compassionate resource when you're seeking further guidance and reassurance. Written by a certified holistic nurse and approved by the most respected professional association of holistic nurses, American Holistic Nurses' Association Guide to Common Chronic Conditions offers a blend of traditional, alternative, and complementary advice that works in conjunction with your doctor's care. Based on the latest scientific research, this holistic self-care guide covers twenty chronic conditions, providing you with the total picture of your condition and explaining in clear, friendly language what you can do to complement your doctor's prescribed treatment. Holistic nurses engage in therapeutic partnerships with their clients, and this book will work with you to help you understand your condition and teach you specific, safe actions you can take to feel better and improve your health.
* Offers a host of self-care measures
* Presents thorough explanations of each condition, from diagnosis to enhanced wellness
* Addresses side effects and reactions to medicines, treatments, and surgery
* Includes cutting-edge research that supports each self-care approach

During the last 8-10 years the research on homocysteine has become very active. Hundreds of articles are now published each year. A disturbed homocysteine metabolism can be an underlying factor for pregnancy complications and fetal malformations, cardiovascular disease, dementia, psychiatric and neurologic disorders and possibly carcinogenesis. A disturbed homocysteine metabolism can in most cases be normalized by treatment with folate and/or vitamines B12 and B6. Many of these findings therefore directly concern most practitioners.

Clinical Imaging of the Small Intestine offers a complete review of small bowel radiology and its applications. With contributions from leading international authorities, the book provides the reader with the pertinent aspects of gastrointestinal radiology, specifically the problems of technique and interpretation that confront radiologists.The second edition was revised to include: - CT and MRI of the small bowel; - Sonography of the small bowel; - Assessing the activity of Crohn's disease with MRI; - Vascular disorders and small bowel obstructions; - Immune deficiency diseases; - Differential diagnosis based on both pathologic and radiologic findings; - New Figures and expanded index.The comprehensive scope of coverage makes this book a highly specialized but nonetheless state-of-the-art reference for those practitioners who have an interest in learning more about intestinal imaging, including radiologists, gastroenterologists and surgeons.

The maturation phenomenon, first described by Ito et al. in 1975, refers to postischemic changes that develop hours or days after an ischemic insult. The delayed neuronal death of CA1 pyramidal cells of the hippocampus is a classic example. The report of the phenomenon boosted research in the field, as it became evident that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention. Since then a growing number of studies have improved our knowledge on mechanisms of cell death and recovery. This volume contains the presentations of the 4th international symposium, held in New Orleans in October/November 1999, grouped in sections covering apoptosis and/or necrosis, neuronal recovery vs. death, and protection against infarction. It outlines the present status of investigations and provides further stimulation for research in this field.

A complete guide to the side-effects and treatments - both conventional and alternative - for endometriosis, from a respected name in the field who also suffers from endometriosis.

Endometriosis is a debilitating reproductive and immunological disease that affects 7-10 million American women each year. The disease occurs when the same kind of tissue that lines the walls of the uterus grows outside the uterus in the pelvic cavity or some other area of the body, usually significantly affecting the woman's fertility and often causing pelvic pain. And as with any condition that affects fertility, the results are often emotional and psychological as well as physical.

As someone who suffers from endometriosis, and who has connections to a wide network of healthcare professionals, Morris is the perfect person to guide sufferers through diagnosis, treatment and living well with the condition. Like the previous titles in our successful Living Well series, this book will offer a holistic approach to living with the disease. The author will offer strategies for coping with the psychological aspects of endometriosis, including how best to tell others about the condition; treatment options including alternative and complementary treatment plans; dealing with infertility; and weighing the hysterectomy option. The author will draw on her relationship with fellow sufferers as well as medical professionals to help readers, making this the most comprehensive guide to endometriosis available.

Kerry-Ann Morris was diagnosed with endometriosis in 1999. Since then she has become one of the most active members of the endometriosis community, and has started an outreach website for the disease.She has relationships with many fellow sufferers and experts in the medical community, making her the perfect author for a book on holistic treatment.

Chronic obstructive pulmonary disease (COPD) is an increasingly important health problem world-wide. Whereas most other leading diseases have shown a decline in the past decades, COPD morbidity and mortality is on a steady increase. Exacerbations are usually defined as an increase in cough, a change in the colour or quantity of sputum, and a worsening dyspnea. The role of bacterial infections and the efficacy of antimicrobial therapy in acute exacerbations of chronic bronchitis (AECD) is still controversial. Exacerbations of chronic bronchitis are a common occurrence in clinical practice and are a leading cause of antibiotic prescription among respiratory infections. It is still uncertain whether each new exacerbation may deteriorate the natural history of chronic bronchitis. Undoubtedly, every episode includes a temporary worsening in lung function and may therefore pose the threat of respiratory failure or death in more severely obstructed patients.

International specialists in Microbiology, Infectious Diseases, Internal Medicine, Cardiology Immunology, Pneumonology, Neurology and Epidemiology gathered to this workshop to discuss and enhance interdisciplinary knowledge on the possible etiological role of Chlamydia pneumoniae, a widespread human respiratory infection, in the pathogenesis of chronic inflammatory diseases with major public health impact such as atherosclerosis, cardiovascular disease, adult-onset asthma bronchiale, chronic obstructive pulmonary diseases, reactive arthritis, morbus Alzheimer and multiple sclerosis. Current deficits and goals in the standardisation of diagnostic tools, basic and applied research, design of epidemiological and monitoring of therapy studies were identified. A special feature of this book is the comprehensive collection of state-of-the-art review articles in the various fields with many references.

You can feel great again!

"Syndrome X proactively lays out a nutritious, tasty, and simple diet plan to get us back to the basics of healthy nutrition."–Lendon H. Smith, M.D., New York Times bestselling author of Feed Your Body Right

"Syndrome X is the best new book to help you understand the facts about nutrition, health, and aging. . . . It is full of new information and insights most readers have never had access to before. Everyone who values his or her health will want to read the book and then individualize the program to suit his or her needs–the authors have made this easier than ever to do."–Richard A. Kunin, M.D., author of Mega-Nutrition

What is Syndrome X? It’s a resistance to insulin–the hormone needed to burn food for energy–combined with high cholesterol or triglycerides, high blood pressure, or too much body fat. Syndrome X ages you prematurely and significantly increases your risk of heart disease, hypertension, obesity, eye disease, nervous system disorders, diabetes, Alzheimer’s, cancer, and other age-related diseases.

Syndrome X is the first book to tell you how to fight the epidemic disorder that is derailing the health of nearly a third of North Americans. It outlines a complete three-step program–including easy-to-follow diets, light physical activity, and readily available vitamins and nutritional supplements–that will safeguard you against developing Syndrome X or reverse it if you already have it.

An Irish Times book of the year 2022 A powerful, probing book about PTSD. As a journalist Keane has covered conflict and brutality across the world for more than thirty years, from Rwanda, Sudan, South Africa, Somalia, Iraq, Afghanistan, Ukraine and many more. Driven by an irresistible compulsion to be where the night is darkest, he made a name for reporting with humanity and empathy from places where death and serious injury were not abstractions, and tragedy often just a moment's bad luck away. But all this time he struggled not to be overwhelmed by another story, his acute 'complex post-traumatic stress disorder', a condition arising from exposure to multiple instances of trauma experienced over a long period. This condition has caused him to suffer a number of mental breakdowns and hospitalisations. Despite this, and countless promises to do otherwise, he has gone back to the wars again and again. Why? In this powerful and intensely personal book, Keane interrogates what it is that draws him to the wars, what keeps him there and offers a reckoning of the damage done. PTSD affects people from all walks of life. Trauma can be found in many places, not just war. Keane's book speaks to the struggle of all who are trying to recover from injury, addiction and mental breakdown. It is a survivor's story drawn from lived experience, told with honesty, courage and an open heart.

Gastroesophageal reflux (GER) refers to symptoms and events that result from abnormal regurgitation of gastric contents into the esophagus. GER is a common clinical problem that affects large segments of the general population. The spectrum of problems associated with GER is now known to also involve extra-esophageal sites. Respiratory diseases, in particular bronchial asthma, can be exacerbated by multiple triggers, including GER. The relationship between the occurrence of gastroesophageal disorders and changes in respiratory function has been known for over a century, but the mechanism by which intraesophageal acid regurgitation can produce respiratory symptoms is still debated. The reasons for these concurrent pathological events are also not fully understood. Determining, for instance, whether reflux itself initiates or exacerbates asthma, or whether asthma or its treatment primarily causes GER is a matter of current investigation.

The Maturation Phenomenon, described by Ito et al. in 1975 [3) on the basis of his to logical observations in the hippocampus as well as other portions of the cerebral hemisphere, refers to the hours or days of delay in the development of pathological changes in various parameters of ischemic injury following the restoration of blood flow to the ischemic brain. There is a direct relationship between the intensity of ischemic insult and the speed and rate of maturation of ischemic injury, a lesser intensity being associated with slower and less severe development of the lesions. The delayed neuronal death of CAl pyramidal cells of the hippocampus [8) is a classic example. In the cerebral cortex, with increasing intensity of the ischemic insult, the maturation phenomenon of ischemic injuries intensifies, seamlessly, from less exten sive to more extensive disseminated selective neuronal necrosis (DSNN), and then further to cerebral infarction upon reaching a critical threshold [1,2,4,6,7). We also have found that following ischemic insults just under the threshold level required to induce infarction, only disseminated selective neuronal necrosis (DSNN) progresses, while following ischemic insults at the threshold level, initially only DSNN develops, followed by the evolution of a gradually enlarging infarcted focus [5, 7). The reporting of this phenomenon boosted research in the field, as it became evi dent that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention.

"Syndrome X proactively lays out a nutritious, tasty, and simple diet plan to get us back to the basics of healthy nutrition."–Lendon H. Smith, M.D., New York Times bestselling author of Feed Your Body Right

"Syndrome X is a well-written, easy–to–follow guide that provides life–saving information for the whole family. This book offers a smart and easy solution to the problem of insulin resistance. It also provides terrific information on how to lose weight without losing your mind in the process. The recipes are great—you'll want to keep a copy in your kitchen."–Carol Colman, New York Times bestselling coauthor of Shed 10 Years in 10 Weeks and Stop Depression Now

"Syndrome X could very well be the next public health crisis, and the information in this book can keep you from becoming another statistic. The nutritional and supplement advice in Syndrome X should help you stay healthy and lean."–Fred Pescatore, M.D.,author of Feed Your Kids Well and Thin For Good

"Syndrome X clearly shows the importance of antioxidant supplementation in keeping you healthy and preventing disease."–Lester Packer, Ph.D., author of The Antioxidant Miracle; director of the Packer Lab, The University of California at Berkeley

"Syndrome X is the best new book to help you understand the facts about nutrition, health, and aging. . . . It is full of new information and insights most readers have never had access to before. Everyone who values his or her health will want to read the book and then individualize the program to suit his or her needs the authors have made this easier than ever to do."–Richard A. Kunin, M.D., author of Mega-Nutrition

"A much-needed guide for the millions who have Syndome X and don't know it until they suffer serious health consequences. I am recommending it to my many patients who have this problem."–Priscilla Slagle, M.D., author of The Way Up from Down

"Superb. . . . The concepts in Syndrome X need to be understood by every person seeking or giving advice about symptoms like fatigue, lack of vigor, and mental fuzziness."–Hugh D. Riordan, M.D., President, the Center for the Improvement of Human Functioning

Male infertility is a clinician-orientied book aimed at the clinician dealing with the infertile couple because rational, effective management is only possible if the couple are considered together. The aim of the work is to provide advice to the clinician and to give reference to the underlying science. This will not only enable clinicians to understand the underlying science but will also give scientists an insight to clinical work. This blend of science and clinical work is reflected in the contributors who are experts drawn from both fields.

Functional somatic syndromes are defined as physical syndromes without an organic disease explanation, demonstrable structural changes, or established biochemical abnormalities. This book reviews the state of scientific and clinical understanding of the nine most common functional somatic syndromes. For each syndrome, expert contributors provide a brief historical perspective, a current definition, a case presentation, confirmatory and contradictory research findings, a discussion of the leading pathogenetic hypotheses, and guidelines for diagnosis and treatment. Chapters offer advice for the determination of disability of patients with these medically unexplained disorders, while describing both medical and psychiatric interventions. Stressing the importance of a sound therapeutic relationship as a basis for treatment, this is an invaluable resource for professionals in primary care and many other disciplines.

A practical primer for physicians wanting to learn about simple and complex urodynamic testing. The clear, concise workbook structure allows for quick reference to multichannel urodynamic tracings and their interpretation. Brief but thorough discussion of the underlying theory and concepts behind urodynamic testing enable readers to gain a firm grasp of the implications of test results in individual patients. It provides an understanding of all the techniques used for the evaluation and treatment of the incontinent or lower urinary tract dysfunctional female patient, and also includes a quick reference guide to outpatient treatment. In contrast to other didactic texts, this book allows readers to initiate testing programs and will thus be of practical benefit to all those interested in improving patient care.

Peroxisomal disorders constitute a major research front in clinical genetics, paediatrics and cell biology. Since 1983, the metabolic defect in some 20 different peroxisomal disorders has been described. The best known conditions include Zellweger syndrome, rhizomelic chondrodysplasia punctata and X-linked adrenoleukodystrophy and, in the most recent edition of The Metabolic and Molecular Basis Inherited Disease, edited by Scriver and colleagues, more than 100 pages are now devoted to the subject. Progress in our understanding of these conditions, and their diagnosis, results from the application of a variety of laboratory investigations. These include microscopic studies, analysis of metabolites (very long-chain fatty acids, bile acids, and plasmalogens), enzyme studies (peroxisomal beta-oxidation pathway and dihydroxyacetone phosphate acyltransferase), immunodetection of peroxisomal (membrane) proteins and molecular analysis of mutant DNA. In order to encourage a greater awareness in this field and the diagnostic protocols required, an international course was organised in Gent, Belgium, in May 1994, on the clinical and biochemical diagnosis of peroxisomal disorders. A number of international experts in the field who provided intensive hands-on experience over 3.5 days, have now collected their course work and reviews together in this Handbook. The volume is introduced by Sidney Goldfischer, who in 1973 was the first to recognise the absence of peroxisomes in Zellweger syndrome, but whose observations were not fully appreciated for a further decade. This handbook provides the most comprehensive and detailed account of laboratory methods for the diagnosis of peroxisomal disorders. The methods are clearly presented and well illustrated, and should allow laboratories to introduce these methods into their repertoire. Audience: Paediatricians, neurologists, clinical biochemists, pathologists, genetic counsellors, obstetricians, and GPs interested in the recognition, diagnosis and prenatal prevention of peroxisomal disorders.

Rontgenthoraxaufnahmen richtig interpretieren

Thoraxaufnahmen, die auf der Intensivstation aufgenommen werden, unterscheiden sich in der Aufnahmetechnik und in den veranderten physiologischen und anatomischen Verhaltnissen von Standard-Thoraxaufnahmen, die am Rasterwandstativ angefertigt werden. Die Interpretation dieser Bilder bereitet selbst erfahrenen Radiologen und Intensivmedizinern haufig Schwierigkeiten.

Der Weg zur korrekten Interpretation: - Rontgen- und Aufnahmetechnik - Strahlenschutz und -belastung - Klinische Problematik und Interpretation von Thoraxaufnahmen auf der Intensivstation.

Neu in der 2. Auflage:

Bildmaterial moderner Aufnahmeverfahren

Indikationsstellung fur CT-Aufnahmen

Vergleich von Projektionsradiographie und Schnittbildradiographie und mogliche Pitfalls

Ein Praxisbuch von Radiologen, Intensivmedizinern und Medizinphysikern zum Lernen und Nachschlagen. Ein Muss fur jeden auf der Intensivstation tatigen Arzt "

Cryptorchidism remains a common but poorly understood anomaly affecting 2%-5% of children. Major controversies exist over the timing and type of treat ment (i. e. surgical vs hormonal therapy) and whether intervention prevents sub sequent infertility and testicular cancer. Part of the dilemma is caused by lack of understanding of the normal process of descent, despite intensive research and study since the eighteenth century, when Hunter and von Haller first described the gubernaculum (caudal genito-inguinal ligament) and processus vaginalis (Williams and Hutson 1991a). More needs to be known, not only of the normal mechanism, but also of the ways that it can be deranged to produce undescended testes. This review describes the recent results of studies on normal descent, with emphasis on our studies of the different stages of descent. As the reader will appreciate, the ever-more complex models proposed to account for normal tes ticular descent predict that undescended testes will be caused by a multitude of anomalies affecting different stages of the process. A description is given of current hypotheses of the aetiology of cryptorchidism, correlating these with studies of cryptorchid animal models. For a more detailed description of the numerous ideas about the mechanism, the reader is referred to Heyns and Hutson (1995) and other monographs (Fonkalsrud and Mengel 1981; Abney and Keel 1989)."

Adhesions can cause a wide range of problems, complaints and hazards, even after simple abdominal procedures, such as appendectomy, with complications ranging from recurrent discomfort and pain to intestinal obstruction. Postsurgical adhesions increase the risk of following operations of the abdominal and thoracic cavity. They impair peritoneal dialysis and chemotherapy and play a crucial part in laparoscopic procedures. Adhesion-related problems account for a large amount of clinical work and have a significant socioeconomic impact. This book presents the current knowledge on the aetiopathogenesis of adhesion formation as well as the available methods for their prevention and control. Experts in the field contribute to clinical standards for preventive measures to control the formation of postoperative adhesions

An all-in-one illustrated guide to human anatomy with encyclopedic coverage from bones and muscles to systems and processes. This in-depth manual to the human body's physical structure, chemical workings, and potential problems is a must-have reference to help further your studies or knowledge of how our bodies work.

Each page of The Human Body Book, updated to reflect the latest medical advances, is illustrated with colourful and comprehensive diagrams, which are thoroughly annotated to take you right into the cells and fibres that are responsible for keeping the human body ticking.

The opening chapter, Integrated Body, explains how the parts of the body work together at various levels of size and hierarchy to produce the living whole. It also contains an overview of the major body systems, enlivened by real-life 3D medical scans of the entire body. The chapters that follow provide coverage of the body function by function, system by system. Eleven main body systems are covered in turn, with each section ending on common injuries, diseases, and disorders afflicting that system. The book concludes with a chapter on Growth and Development which looks in detail at how the body changes over the course of a human lifespan.

The articles in Issue 4 of JOURNAL OF INHERITED METABOLIC DISEASE, Volume 16 (1993) contain the main lectures presented at the 30th Annual Symposium of the Society for the Study of Inborn Errors of Metabolism (SSIEM), Leuven, Belgium, 1992, which was dedicated to Inherited Metabolic Diseases and the Brain'. Topics discussed included: Inborn errors and brain fluids, neurotransmitter disorders, inborn errors and demyelination, and recent developments. Participants from many countries provided a state-of-the-art review which will be of interest to clinicians and research workers alike in many different disciplines.