JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

An accessible, comforting and practical book for anyone experiencing anxiety, from the author of The Recovery Letters and How to Tell Depression to Piss Off. Despite more and more people opening up about their mental health, anxiety is still taboo. We're not supposed to be anxious; we're supposed to be resilient and able to 'get on with it'. We are expected to excel while juggling a hectic, pressurised schedule at home and at work, despite the lines between the two being more blurred than ever. This book dispels that taboo. It is for anyone who has experienced general anxiety disorder, trauma-related anxiety, clinical anxiety and those with 'low-level' anxieties. At once empathetic and entertaining, How to Tell Anxiety to Sod Off offers 40 ways to get to a better place with anxiety. They are born out of the author's personal experience of managing his own anxiety and his many years of working as a counselor helping people with their mental health.

Do you suffer from ongoing pain or other chronic medical symptoms such as fatigue, lower back pain, arthritis, acid indigestion, insomnia, or migraines? Do you feel as though your symptoms are taking over your life?

Thirty percent of the population suffers from chronic debilitating illnesses and pain that respond only partially to conventional medicine, but this doesn't mean that there is no relief in sight. Dr. Arthur Barsky, psychiatrist and pioneer in the field of mind-body medicine, has found that changing the way you think about your illness can have a remarkable effect on how you experience your symptoms. The groundbreaking program he offers in "Stop Being Your Symptoms and Start Being Yourself" teaches patients to master the five psychological factors that make chronic symptoms persist through hundreds of exercises, worksheets, and patient examples.

You may not be able to completely eliminate your medical symptoms, but it is possible to control your symptoms rather than letting them control you--and this book shows you how.

Now in paperback, the bestselling exploration of the effects of the mind-body connection on stress and disease

Can a person literally die of loneliness? Is there such a thing as a ""cancer personality""? Drawing on scientific research and the author's decades of experience as a practicing physician, this book provides answers to these and other important questions about the effect of the mind-body link on illness and health and the role that stress and one's individual emotional makeup play in an array of common diseases.Explores the role of the mind-body link in conditions and diseases such as arthritis, cancer, diabetes, heart disease, IBS, and multiple sclerosisDraws on medical research and the author's clinical experience as a family physicianIncludes The Seven A's of Healing-principles of healing and the prevention of illness from hidden stress

Shares dozens of enlightening case studies and stories, including those of people such as Lou Gehrig (ALS), Betty Ford (breast cancer), Ronald Reagan (Alzheimer's), Gilda Radner (ovarian cancer), and Lance Armstrong (testicular cancer)

An international bestseller translated into fifteen languages, "When the Body Says No" promotes learning and healing, providing transformative insights into how disease can be the body's way of saying no to what the mind cannot or will not acknowledge.

A book which surveys the world of the skin and its microflora, in health and disease, and in animals as well as man. The approach is essentially an ecological one, moving from the physical and chemical properties of the skin as a microbial habitat, through a consideration of the various major groups of microorganisms associated with it, to an account of the complex associations between these microorganisms. The skin flora in health is introduced as a prelude to the understanding of microbial skin disease, and the mechanisms of pathogenicity are explained as the major groups of infective skin conditions are reviewed. The principles of treatment, disinfection and prevention receive proper attention, as does the important topic of hospital-acquired infection, where the skin is so often implicated. The text is accompanied by numerous tables containing a wealth of practical and experimental detail, and is extensively referenced. This is a book which will be essential to dermatologists, medical microbiologists, veterinarians and research workers in these fields.

Utilizing a syndrome-based approach, "Respiratory Infections "provides pulmonologists, infectious disease specialists, and immunologists with essential and thorough knowledge of respiratory infections and the multitude of diseases that make us these infections, including pneumonia, tuberculosis, HIV, and cystic fibrosis. The only source to bridge the gap between respiratory infections and infectious disease, this text advises the clinician on how to easily and rapidly identify, treat, and manage respiratory infections.A

Key features of this integral resource include:

Are you looking for concise, practical answers to questions that are often left unanswered by traditional pancreatic disease references? Are you seeking brief, evidence-based advice for complicated cases or complications? Curbside Consultation of the Pancreas: 49 Clinical Questions provides quick and direct answers to the thorny questions commonly posed during a "curbside consultation" between colleagues.Dr. Scott Tenner, Dr. Alphonso Brown, and Dr. Frank Gress have designed this unique reference, which offers expert advice, preferences, and opinions on tough clinical questions commonly associated with pancreatic disease. The unique Q&A format provides quick access to current information related to pancreatic disease with the simplicity of a conversation between two colleagues. Numerous images, diagrams, and references are included to enhance the text and to illustrate the treatment of pancreatic disease patients. Curbside Consultation of the Pancreas: 49 Clinical Questions provides information basic enough for residents while also incorporating expert advice that even high-volume clinicians will appreciate. Gastroenterologists, fellows and residents in training, surgical attendings, and surgical residents will benefit from the user-friendly and casual format and the expert advice contained within. Some of the questions that are answered: * How do I determine the amount of fluids to provide to patients with acute pancreatitis? * When should antibiotics be used in acute pancreatitis? * How do I determine the timing of re-feeding patients with acute pancreatitis? * What is the best way to treat pain in patients with chronic pancreatitis? * How should I define the best approach to a pseudocyst?

The increased incidence of pancreatic cancer in the Western world and its grave prognosis has resulted in an urgency for research in this area. Until now the available data on toxicology of the pancreas has been few and fragmentary, scattered throughout the literature. A benchmark volume, Toxicology of the Pancreas pulls together information in this neglected area of toxicological research and highlights fundamental research performed in the last ten years. Leaders in the field discuss important structures, the detoxification and toxification process at the cellular and sub-cellular level, the distribution of phase 1 and phase 2 drug-metabolizing enzymes and their role in pancreatic disease, and the role of diet and toxicants on pancreatic disease. The book also covers the role of altered genes in the integrity of the pancreas and explores comparative toxicology in humans and in the lab species used in testing. Illustrated with histological, electron microscopical, and immunohistochemical formats, this book provides a comprehensive and novel presentation of biological and toxicological data. It stands alone as a reliable resource of information easily accessible to professionals in different disciplines.

When "Rats, Lice and History" appeared in 1935, Hans Zinsser was a highly regarded Harvard biologist who had never written about historical events. Although he had published under a pseudonym, virtually all of his previous writings had dealt with infections and immunity and had appeared either in medical and scientific journals or in book format. Today he is best remembered as the author of "Rats, Lice, and History," which gone through multiple editions and remains a masterpiece of science writing for a general readership.

To Zinsser, scientific research was high adventure and the investigation of infectious disease, a field of battle. Yet at the same time he maintained a love of literature and philosophy. His goal in "Rats, Lice and History" was to bring science, philosophy, and literature together to establish the importance of disease, and especially epidemic infectious disease, as a major force in human affairs. Zinsser cast his work as the "biography" of a disease. In his view, infectious disease simply represented an attempt of a living organism to survive. From a human perspective, an invading pathogen was abnormal; from the perspective of the pathogen it was perfectly normal.

This book is devoted to a discussion of the biology of typhus and history of typhus fever in human affairs. Zinsser begins by pointing out that the louse was the constant companion of human beings. Under certain conditions-to wash or to change clothing-lice proliferated. The typhus pathogen was transmitted by rat fleas to human beings, who then transmitted it to other humans and in some strains from human to human.

"Rats, Lice and History" is a tour de force. It combines Zinsser's expertise in biology with his broad knowledge of the humanities

Joining the ranks of modern myth busters, Dr. Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth. Through a fresh and engaging examination of our evolutionary history, Dr. Moalem reveals how many of the conditions that are diseases today actually gave our ancestors a leg up in the survival sweepstakes. But Survival of the Sickest doesn't stop there. It goes on to demonstrate just how little modern medicine really understands about human health, and offers a new way of thinking that can help all of us live longer, healthier lives.

Are you looking for concise, practical answers to questions that are often left unanswered by traditional medical searches? Are you seeking brief, evidence-based advice for complicated cases or complications? "Curbside Consultation of the Colon: 49 Clinical Questions "provides quick and direct answers to the thorny questions commonly posed during a "curbside consultation" between colleagues.
Dr. Brooks D. Cash has designed this unique reference, which offers expert advice, preferences, and opinions on tough clinical questions commonly associated with the colon. The unique Q&A format provides quick access to current information related to the colon with the simplicity of a conversation between two colleagues. Numerous images, diagrams, and references are included to enhance the text and to illustrate the treatment of the colon.
"Curbside Consultation of the Colon: 49 Clinical Questions "provides information basic enough for residents while also incorporating expert advice that even high-volume clinicians will appreciate. Gastroenterologists, fellows and residents in training, surgical attendings, and surgical residents will benefit from the user-friendly and casual format and the expert advice contained within.
Some of the questions that are answered:
- What is the appropriate evaluation for fecal incontinence?
- What colonic infections are associated with AIDS?
- What are the current colorectal cancer screening and surveillance recommendations?
- What is the best way to manage chronic constipation?
- Where do probiotics fit into the management of IBS?
- How should diverticulitis be managed?
- What is colonic pseudo-obstruction and how is itmanaged?

This concise pocket guide to urological investigative procedures reviews the indications and pitfalls of tests before they are requested and suggests which investigations should be performed in individual urological conditions.

Part I describes principles, methodology, advantages and disadvantages of each investigation and covers all urological investigations/tests from simple X-ray of the abdomen (KUB) to PET scanning. Part II offers advice on the choice of investigations for individual urological conditions. For each investigation in Part I and urological condition in Part II, important bullet points are highlighted in a a ~boxa (TM) - useful during a busy ward round, out-patient clinic, or for last-minute consultation prior a viva examination.

This comprehensive yet easy-to-read hadbook is aimed at urological trainees, urology nurse specialists, recently qualified junior urologists as well as practicing urologists as part of review and audit of practices.

This readable text presents findings from the life science experiments conducted during and after space missions. It provides an insight into the space medical community and the real challenges that face the flight surgeon and life science investigator.

Making Sense of Illness is a fascinating investigation into the social and clinical factors that determine what constitutes a "legitimate" illness in the twentieth century. By examining six case studies of diseases that have emerged within the past fifty years--from what we now consider to be "straightforward" diseases such as coronary heart disease, to the currently widely-debated Chronic Fatigue Syndrome--Aronowitz examines the historical and cultural factors that influence how doctors think about illness; how illnesses are recognized, named, classified, and finally, what they "mean" in an individual and social context. The choices that are available to the investigators, clinicians, patients and the processes by which change occurs are factors that all play a great role in "legitimizing" an illness, and these are the roles that are seldom examined. By juxtaposing the histories of each disease, Aronowitz shows how cultural and historical precedents have determined research programs, public health activities, clinical decisions, and even the patient's experience of illness. This is a must-read for anyone interested in public health and the history of medicine in the United States.

The first edition of A Guide To Assessments That Work provided a much needed resource on evidence-based psychological assessment. Since the publication of the first edition, a number of advances have been made in the assessment field and a revised diagnostic system for mental disorders has been introduced. These changes are reflected in the second edition and new chapters have been included to cover the use of evidence-based assessment instruments and procedures in clinical practice and the use of evidence-based principles to integrate and interpret assessment data. This volume addresses the assessment of the most commonly encountered disorders or conditions among children, adolescents, adults, older adults, and couples. Strategies and instruments for assessing mood disorders, anxiety and related disorders, couple distress and sexual problems, health-related problems, and many other conditions are reviewed by leading experts. With a focus throughout on assessment instruments that are feasible, psychometrically sound, and useful for typical clinical requirements, this edition features the use of a rating system designed to provide evaluations of a measure's norms, reliability, validity, and clinical utility. Standardized tables summarize this information in each chapter, providing essential information on the most scientifically sound tools available for a range of assessment needs. With its focus on clinically relevant instruments and assessment tasks, this volume provides readers with the essential information for conducting the best evidence-based mental health assessments currently possible.

Reifying Women's Experiences with Invisible Illness: Illusions, Delusions, Reality provides a platform that recognizes that the experience of invisible illness is greatly influenced by context and personal circumstance. The contributors to this book include women who exude diversity as it relates to race and ethnicity, career, religious experience, education, social support, and interpersonal relationships. From recent college graduates to senior level professionals, these women share stories that create a space to advocate on behalf of the individual who is chronically ill rather than focusing on the often privileged perspective of medical professionals.

The subject of medical entomology contin- factors such as insecticide susceptibility, vec- ues to be of great importance. Arthropodborne tor competence, host preference and similar im- diseases such as malaria, yellow fever, dengue portant phenomena. Now, a variety of new and filariasis continue to cause considerable methods are available to study genes, and to human suffering and death. Problems in ani- genetically alter important characteristics in mal production, wildlife and pets of humans vectors as a potential means of controlling hu- caused by arthropods still exact a large eco- man and animal diseases. nomic toll. In the past 2 decades, the invasion Many of the traditional tasks of medical en- of exotic pests and pathogens has presented tomologists continue to be important. Arthro- new problems in several countries, including pod systematics is important because the need the USA. For example, the year 1999 saw the for accurate identification of arthropods is vital invasion of the eastern USA by Aedes japonicus, to an understanding of natural disease cycles. an Asian mosquito, and West Nile virus, a mos- Systematics has been made even more challeng- quito-transmitted African arbovirus related to ing because of the current appreciation of the St. Louis encephalitis virus. number of groups of sibling species among vec- At the same time old and new health prob- tors of important disease pathogens. New mo- lems with arthropods occur, the traditional ap- lecular tools are assisting in separating these proaches to arthropod control have become forms.

Keeping pace with the changing face of genetics in ophthalmology, this Second Edition contains new chapters on molecular genetics, thrombophilia, and genetically triggered retinal vascular diseases, as well as offers many new subchapters highlighting current research by recognized leaders in the field.

This authoritative and comprehensive 1996 publication looks in depth at a range of medical syndromes characterised by serious and unpredicted internal overheating of the body. These episodes may arise suddenly and unexpectedly in certain individuals, with life-threatening consequences, either as a result of heat stress, exceptional physical exertion or in response to certain common anaesthetics and some drugs, including ecstasy. The chapters focus on the full range of these syndromes, their metabolic and physiological basis, the important pre-disposing factors for the prediction of those at risk, and the medical management of these conditions. The volume includes important contributions from authors of international repute and incorporates a wealth of information from the Leeds malignant hyperthermia investigation unit. This compilation will be of interest to those wanting to understand these disorders.

From Simon & Schuster, Man and Microbes respected science writer Arno Karlen presents a dramatic panorama of the natural history of disease. Man and Microbes makes clear that infection is a natural and necessary part of life. It shows how the search for food, shelter, and a safer, more prosperous life has altered the environment, changed the dance of adaptation between humans and microbes, and generated new diseases

go beyond standard medical treatment to treat yourself to wellness
Suffering from a serious condition? Do you have questions that your doctor may not have answered-and are you wondering if you're doing everything you possibly can to get and stay well?
Turn to this authoritative, compassionate resource when you're seeking further guidance and reassurance. Written by a certified holistic nurse and approved by the most respected professional association of holistic nurses, American Holistic Nurses' Association Guide to Common Chronic Conditions offers a blend of traditional, alternative, and complementary advice that works in conjunction with your doctor's care. Based on the latest scientific research, this holistic self-care guide covers twenty chronic conditions, providing you with the total picture of your condition and explaining in clear, friendly language what you can do to complement your doctor's prescribed treatment. Holistic nurses engage in therapeutic partnerships with their clients, and this book will work with you to help you understand your condition and teach you specific, safe actions you can take to feel better and improve your health.
* Offers a host of self-care measures
* Presents thorough explanations of each condition, from diagnosis to enhanced wellness
* Addresses side effects and reactions to medicines, treatments, and surgery
* Includes cutting-edge research that supports each self-care approach

Clinical Imaging of the Small Intestine offers a complete review of small bowel radiology and its applications. With contributions from leading international authorities, the book provides the reader with the pertinent aspects of gastrointestinal radiology, specifically the problems of technique and interpretation that confront radiologists.The second edition was revised to include: - CT and MRI of the small bowel; - Sonography of the small bowel; - Assessing the activity of Crohn's disease with MRI; - Vascular disorders and small bowel obstructions; - Immune deficiency diseases; - Differential diagnosis based on both pathologic and radiologic findings; - New Figures and expanded index.The comprehensive scope of coverage makes this book a highly specialized but nonetheless state-of-the-art reference for those practitioners who have an interest in learning more about intestinal imaging, including radiologists, gastroenterologists and surgeons.

This concise 1993 volume proposes a standardized approach to the investigation of infertility. The volume provides clear guidelines and a logical sequence of steps which will quickly lead the clinician or physician to an accurate diagnosis of the underlying cause of infertility. This standardized approach to the management of infertility will lead to more efficient, systematic and economic care for the infertile couple. The diagnostic charts, which may be photocopied, provide an unambiguous route to diagnosis of the underlying cause of infertility, whilst the text fully explains and describes the essential clinical tests. The volume summarizes the results gained from the study of more than 10,000 infertile couples, who were investigated as part of the WHO's programme to counter the widespread personal distress caused by infertility. It is hoped that the standardized approach presented here will go some way towards countering this major problem.

The maturation phenomenon, first described by Ito et al. in 1975, refers to postischemic changes that develop hours or days after an ischemic insult. The delayed neuronal death of CA1 pyramidal cells of the hippocampus is a classic example. The report of the phenomenon boosted research in the field, as it became evident that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention. Since then a growing number of studies have improved our knowledge on mechanisms of cell death and recovery. This volume contains the presentations of the 4th international symposium, held in New Orleans in October/November 1999, grouped in sections covering apoptosis and/or necrosis, neuronal recovery vs. death, and protection against infarction. It outlines the present status of investigations and provides further stimulation for research in this field.