An award-winning memoir and instant "New York Times" bestseller that goes far beyond its riveting medical mystery, "Brain on Fire" is the powerful account of one woman's struggle to recapture her identity.
When twenty-four-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she'd gotten there. Days earlier, she had been on the threshold of a new, adult life: at the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?
In a swift and breathtaking narrative, Susannah tells the astonishing true story of her descent into madness, her family's inspiring faith in her, and the lifesaving diagnosis that nearly didn't happen. "A fascinating look at the disease that . . . could have cost this vibrant, vital young woman her life" ("People"), "Brain on Fire" is an unforgettable exploration of memory and identity, faith and love, and a profoundly compelling tale of survival and perseverance that is destined to become a classic.

"Diseases and Diagnoses" discusses why such social problems as addiction, sexually transmitted diseases, racial predisposition for illness, surgery and beauty, and electrotherapy, all of which concerned thinkers a hundred years ago, are reappearing at a staggering rate and in diverse national contexts. In the twentieth century such problems were viewed as only historical concerns. Yet in the twenty-first century, we once again find ourselves confronting their implications.

In this fascinating volume, Gilman looks at historical and contemporary debates about the stigma associated with biologically transmitted diseases. He shows that there is no indisputable way to measure when a disease or therapy will reappear, or how it may be perceived at any given moment in time. Consequently, Gilman focuses on the socio-cultural and political implications that the reappearance of such diseases has had on contemporary society. His approach is to show how culture (embedded in cultural objects) both feeds and is fed by the claims of medical science-as for example, the reappearance of "race" as a cultural as well as a medical category.

If the twentieth century was the "age of physics," in the latter part of the past century and certainly in the twenty-first century biological concerns are recapturing central stage. Achievements of the biological sciences are changing the public's sense of what constitutes cutting-edge science and medicine. None has captured the public imagination more effectively than the mapping of the human genome and the promise of genetic manipulation, which fuel what Gilman calls a "second age of biology." Although not without controversy, the role of genetics appears to be key. Gilman puts contemporary debates in historical context, showing how they feed social and cultural concerns as well as medical possibilities.

Research into the role of diet in chronic disease can be difficult to interpret. Measurement errors in different studies often produce conflicting answers to the same questions. Seventh-day Adventists and other groups with many vegetarian members are ideal study populations because they have a wide range of dietary habits that adds power and clarity to research findings.

This book analyses the results of such studies, focusing on heart disease and cancer. These studies support the benefits of a vegetarian diet and in addition provide evidence about the effects of individual foods and food groups on disease risk that is relevant to all who are interested in good health. The author places the findings in the broader context of well-designed nutritional studies of the general population. He discusses the degree of confidence we can have in particular relationships between diet and disease based on the strength of the evidence. The book is written in a clear style with an extensive glossary, and should be accessible to a wide audience.

Addressing a major field of interest for oncologists, cell biologists, and other biomedical researchers, Beyond Apoptosis provides an overview of how different biological mechanisms of cell death, senescence and mitotic catastrophe stop the growth of tumor cells treated with anticancer agents.

Written by internationally renowned contributors, this text includes:

• morphological illustrations, as well as a DVD containing documents and video clips from various time-lapse microscopic studies of cell death and mitotic catastrophe
• the role and limitations of apoptosis as a determinant of the toxicity of anticancer agents
• alternative mechanisms of the antiproliferative actions of anticancer drugs and radiation, such as non-apoptotic cell death, cell senescence, and mitotic catastrophe
• non-apoptotic forms of cell death, such as necrosis, paraptosis, autophagic cell death, and others
• morphological and kinetic differences of the various forms of cell death

Written with a broader perspective and knowledge, Cancer Supportive Care: Advances in Therapeutic Strategies presents state-of-the-art management options for the full range of symptoms, toxicities, and complications experienced by cancer patients. In addition to "bread and butter" topics such as pain control and nausea and vomiting, the book contains unique, ground-breaking discussions of symptom measurement, the role of growth factors, and late effects and cancer survivorship. Written by key opinion leaders in the field, Cancer Supportive Care: Advances in Therapeutic Strategies: assembles and synthesizes state-of-the-art information into one convenient resource, helping busy clinicians learn the most effective supportive care strategies available discusses emerging therapies and approaches covers topics not included in other cancer supportive care books, such as measurement of symptoms, growth factors, thromboembolism, skeletal complications, fatigue, the elderly cancer patient, cancer survivorship, and alternative and integrative therapies

Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides an authoritative discussion of strategies to effectively implement and interpret the new ASCO/NCCN directives. Standing as the only up-to-date source to readily examine exciting new translational science findings regarding the biology of cancer-associated thrombosis, as well as new clinical recommendations, this guide supplies an authoritative and current discussion of the mechanisms, management, and prevention of cancer-associated thrombosis.

This reference discusses best practices for the management of patients with cancers of the esophagus, stomach, colon, liver, and pancreas. Focusing on a wide variety of GI carcinomas by organ and tumor type, this source provides expert coverage of diagnostic, staging, and treatment procedures by seasoned oncologists and radiologists, and offers in-depth discussions of current research regarding tumor markers, molecular biology, and clinical presentation.

A must for the busy clinician, this source:

• spans the existing evidence from experienced opinion leaders in the field of gastrointestinal oncology
• pairs organ-based chapters so that surgical and non-surgical oncologists provide perspectives on the same condition supplies an up-to-date and relevant summary of the key topics in gastrointestinal oncology, supported by clear scientific evidence
• combines surgical and medical approaches to cancers in specific organs, supplying a rigorous evidence-based approach to the evaluation of various treatments
• addresses critical topics in the area including the management and prevention of cancers around the gastroesophageal junction, rectal cancer, and gastrointestinal stromal tumors
• considers the latest developments in surgical, radiation, and chemotherapeutic management

Considering the impact of translational breakthroughs on the early detection, diagnosis, prevention, and treatment of breast cancer, this all-encompassing guide collects cutting-edge research on the most promising strategies and agents likely to impact the management and long-term outcomes of women with breast cancer. This book will provide current information on rapidly evolving translational therapies, as well as improved strategies for the selection of patients for these treatments.

about the book... Assisting clinicians in the differential diagnosis of the wide range of disorders responsible for fever of unknown origin (FUO), this source stands as the only recent and comprehensive differential diagnosis of these conditions. This guide provides a clear overview of diagnostic approaches and offers expert recommendations that are invaluable to anyone caring for patients with prolonged undiagnosed fever. Written by clinicians for clinicians, this single authoritative source emphasizes the syndromic approach in the diagnosis of FUOs...discusses the etiology and distribution of disorders causing FUOs...and stresses the importance of a focused history, physical examination, and laboratory tests in the differential diagnosis of the FUO patient. about the editor... BURKE A. CUNHA is Chief, Infectious Disease Division, Winthrop-University Hospital, Mineola, New York, and Professor of Medicine, State University of New York School of Medicine, Stony Brook. Dr. Cunha is the author or coauthor of more than 150 abstracts, 100 electronic publications, 1000 articles, and 150 book chapters. He has edited 20 books on various infectious disease topics and is Editor-in-Chief of the journals Infectious Disease Practice and Antibiotics for Clinicians. Dr. Cunha is a Fellow of the Infectious Diseases Society of America. Dr. Cunha is internationally recognized as a teacher-clinician and is the recipient of many teaching awards including the prestigious Aesculapius Award. Dr. Cunha is a Master the American College of Physicians awarded for lifetime achievement as a master clinician and teacher of infectious diseases. Dr. Cunha received the M.D. degree from Pennsylvania State UniversityCollege of Medicine, Hershey.

About the book: Standing alone as the first definitive and comprehensive book on the subject, this guide describes the most recent studies on the brain-gut connection and psychosocial issues related to patients experiencing visceral pain. Bringing together leading experts from the top-tiers of the science, this source provides 33 engaging chapters and spans basic concepts in pharmacology, neurobiology, physiology, and psychology to provide a practical approach to the treatment of chronic pain. Examining a condition that affects up to 25% of the general U.S. population, this source is the only book on the subject to cover both clinical syndromes and neurobiology and ranges from basic mechanisms to diagnosis and clinical treatment of specific syndromes including inflammatory bowel disease, functional abdominal pain, dyspepsia, non-cardiac chest pain, and pelvic pain syndromes; analyses the latest scientific advances including the role of functional imaging in patient care; integrates fundamental scientific concepts with a practical clinical approach; and; supplies 250 figures, and more than 16 color photographs. About the editors: P.Jay Pasricha is Chief, Division of Gastroenterology research that includes pain and motility disorders. Dr. Pasricha has served on numerous national gastroenterological committees and on NIH panels. He holds several patents related to gastrointestinal diagnostics and therapeutics and is a consultant to many companies. He received the M.D. degree (1982) from the All-India Institute of Medical Sciences, New Delhi. William D. Willis is Director, Cecil H. and Ida M. Green Chair, and Chief of the Division of Comparative Neurobiology, Marine Biomedical Institute; Professor and Chairman, Department of Anatomy & Neurosciences; and Professor, Department of Physiology & Biophysics; University of Texas Medical Branch, Galveston. Dr.Willis has been President of the Society for Neuroscience (1984-1985), the Association of Neuroscience Departments and Programs (1982-1983), and the American Pain Society (1982-1983). He has also been on the Executive Committee of the American Association of Anatomists (1982-1986) and the Council of the International Association for the Study of Pain (1984-1990). He received the M.D. degree (196) from the University of Texas Southwestern Medi Gebghart is Head, Department of Pharmacology, University of Iowa, Iowa City. The author or editor of numerous professional publications, he is editor-in-chief of the Journal of Pain and is the recipient of the Purdue Pharma Prize for Pain Research (2004).

This first reference to comprehensively address both the medical and surgical management of diseases affecting the colon, this source spans the wide array of colorectal disorders including rectal prolapse, irritable bowel syndrome, benign and malignant colonic tumors, fissures and ulcers, and Crohn's colitis, among other ailments. With chapters by world leaders in the field, this guide analyzes diagnostic and imaging techniques for disease evaluation and management including advances in colonoscopy, radiology, and surgery.

'Billy Connolly says he's no idea who Parkinson was and just wishes he'd kept his disease to himself. He should read this book.' Jeremy Paxman Parkinson's disease is one of the most common forms of dementia, with 10,000 new cases each year in the UK alone, and yet few know anything about the man the disease is named after. In 1817 - exactly 200 years ago - James Parkinson (1755-1824) defined the disease so precisely that we still diagnose it today by recognising the symptoms he identified. The story of this remarkable man's contributions to the Age of the Enlightenment is told through his three passions - medicine, politics and fossils. As a political radical Parkinson was interrogated over a plot to kill King George III and revealed as the author of anti-government pamphlets, a crime for which many were transported to Australia; while helping Edward Jenner set up smallpox vaccination stations across London, he wrote the first scientific study of fossils in English, which led to fossil-hunting becoming the nation's latest craze - just a glimpse of his many achievements. Cherry Lewis restores this neglected pioneer to his rightful place in history, while creating a vivid and pungent portrait of life as an 'apothecary surgeon' in Georgian London.

Providing a detailed coverage that is impossible in broader-based textbooks, "Urogenital Ultrasound, Second Edition", is a comprehensive study of genitourinary ultrasound that has been completely revised to keep up-to-date with this rapidly changing field. Reflecting the obviously visual nature of ultrasound imaging, "Urogenital Ultrasound, Second Edition" contains more than 1,000 images, including those from more technically advanced ultrasound machines than were in the first edition. Aiding the reader in recognizing various disease states and recommending effective therapeutic or surgical measures, this new edition also covers all recent developments, explained in a pragmatic style that is easily read and understood.

A detailed compilation of the latest research and recommendations for the diagnosis and assessment of esophageal disorders, this reference delves into a wide range of applications and technologies currently utilized in the field including radiology, endoscopy, endoscopic ultrasonography, manometry, ambulatory manometry, pH testing, catheter-free pH testing, bilitec monitoring, and impedance plethysmography.

This reference is the most current and comprehensive source on the many aspects of sarcoidosis, covering topics ranging from the basic science and pathophysiology of the disease to patient evaluation and treatment. It provides a detailed analysis of the pulmonary aspects of the condition and includes chapters on radiographic manifestations, bronchoalveolar lavage research, pulmonary function studies, and proposed markers for the diagnosis and management of the disease.

The increased incidence of pancreatic cancer in the Western world and its grave prognosis has resulted in an urgency for research in this area. Until now the available data on toxicology of the pancreas has been few and fragmentary, scattered throughout the literature. A benchmark volume, Toxicology of the Pancreas pulls together information in this neglected area of toxicological research and highlights fundamental research performed in the last ten years. Leaders in the field discuss important structures, the detoxification and toxification process at the cellular and sub-cellular level, the distribution of phase 1 and phase 2 drug-metabolizing enzymes and their role in pancreatic disease, and the role of diet and toxicants on pancreatic disease. The book also covers the role of altered genes in the integrity of the pancreas and explores comparative toxicology in humans and in the lab species used in testing. Illustrated with histological, electron microscopical, and immunohistochemical formats, this book provides a comprehensive and novel presentation of biological and toxicological data. It stands alone as a reliable resource of information easily accessible to professionals in different disciplines.

The Understanding GERD chart presents a detailed overview of the symptoms and causes of Gastroesophageal Reflux Disease (GERD). Several views show normal esophagus and stomach anatomy, as well as GERD, esophagitis and Barrett's esophagus. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).

Pain is the number-one reason American visit their doctors, Back pain, muscle aches, arthritis affect millions of people daily, limiting their activities and costing billions in medical care. Much of this suffering is unnecessary. Where It Hurts and Why can help readers take charge of their pain and become proactive in their own recovery. Individual chapters provide detailed recommendations for specific areas of the body, and also instructions for immediate treatment of acute pain.